@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu00010: (2016-06-01 )
MENILDLWNQALAQIEKKLSKPSFETWMKSTKAHSLQGDTLTITAPNEFARDWLESRYLHLIADTIYELTGEELSIKFVIPQNQDVEDFMPKPQVKKAVKEDTSDFPQNMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIDHNPSAKVVYLSSEKFTNEFINSIRDNKAVDFRNRYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNTLHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPSSKPKVITIKEIQRVVGQQFNIKLEDFKAKKRTKSVAFPRQIAMYLSREMTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLADDEQLQQHVKEIKEQLK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140-----.........150.......160.......170.......180.......190.......200..--.-.-.-..210.......220.---...-------...230.......--------240........250.......260.......270.......280.......290.......300.......310.-.....--..320.......330---.........340.......350.......360.......370......--.380.-......390......-----.400.......410.......420.......430.......440....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
E
N
I
L
D
L
W
N
Q
A
L
A
Q
I
E
K
K
LSKP
S
F
E
T
W
M
K
STKAHSLQG
D
T
L
T
I
TA
P
N
E
F
A
R
D
W
L
E
S
R
Y
L
H
L
I
A
D
T
I
Y
E
LTGE
E
L
S
I
K
F
V
IPQNQ
D
V
E
D
FMP
K
P
Q
V
K
K
A
V
K
ED
T
S
DF
P
Q
N
MLNPK
Y
T
F
D
T
F
V
IGSGN
R
F
A
H
A
A
S
L
A
VAEAP-------AKAY
N
P
L
F
I
YGGVGL
G
K
T
H
L
M
H
A
I
G
H
Y
V
IDHNPS
A
K
V
V
Y
L
S
S
E
K
F
T
N
E
F
I
N
S
IRDNKA
V
D
F
R
N
R--Y-R-N-V
D
V
L
L
IDD
I
Q
F
LAGK
E
---
Q
T
Q
-------
E
E
F
F
H
T
F
N
T
L
H
EE--------S
K
-
Q
I
V
ISSDRPPKEIP
T
L
E
D
R
L
R
S
R
FEWGLITDITPP
D
L
E
T
R
I
A
I
L
R
K
K
AKAEGLDI
P
N
E
V
M
L
Y
I
A
N
Q
ID
S
-
N
I
-
R
E
L
E
G
--
A
L
I
R
V
V
A
Y
S
S
L
IN-----KDI
N
A
D
L
A
A
E
A
L
K
D
IIPSSK
P
K
V
I
T
I
K
E
I
Q
R
V
VGQQF
N
I
K
L
E
D
FKAKK--RTKSV-A
F
P
R
Q
I
A
M
Y
L
S
R
EMT-----DSS
L
P
K
I
G
E
E
FGGRDH
T
T
V
I
H
A
H
E
K
I
S
K
L
LA
D
D
E
Q
L
Q
Q
H
V
K
E
I
K
E
QLK
43
HHSearch
93.57
38%
-90
- C2 -
1L8Q
2
DNAA_AQUAE
A:
[3-319]
-------------------------------------------------------------------------------------------------------------
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
-------
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
K
R
--
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
--
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
---
R
T
Q
-------
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
E
-
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
-
N
V
-
R
E
I
E
G
--
K
I
K
L
I
K
L
K
G
F
E
G
L
--------
E
R
--
K
---------
E
R
-
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
--
R
N
K
R
T
-
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
-----
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
K
--
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
-
23
PsiBlast_CBE
93.07
39%
-90
- C2 -
3R8F
3
DNAA_AQUAE
D:
[2-297]
------------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
-------
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
--
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
--
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
---
R
T
Q
-------
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
-
N
V
-
R
E
I
E
G
KI
K
L
I
K
L
K
G
F
E
G
L
E
R
-----
K
E
--------------
R
K
E
R
D
K
L
M
Q
I
V
E
F
---
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
---
N
K
R
T
-
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
-----
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
--------------------------
24
PsiBlast_CBE
92.66
39%
-89
- C2 -
3R8F
4
DNAA_AQUAE
C:
[2-297]
------------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
-------
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
--
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
--
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
---
R
T
Q
-------
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
-
N
V
-
R
E
I
E
G
KI
K
L
I
K
L
K
G
F
E
G
L
E
R
-----
K
E
--------------
R
K
E
R
D
K
L
M
Q
I
V
E
F
---
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
---
N
K
R
T
-
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
-----
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
--------------------------
25
PsiBlast_CBE
92.41
39%
-88
- C2 -
3R8F
4
DNAA_AQUAE
B:
[2-297]
------------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
-------
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
--
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
--
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
---
R
T
Q
-------
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
-
N
V
-
R
E
I
E
G
KI
K
L
I
K
L
K
G
F
E
G
L
E
R
-----
K
E
--------------
R
K
E
R
D
K
L
M
Q
I
V
E
F
---
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
---
N
K
R
T
-
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
-----
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
--------------------------
3
PsiBlast_PDB
92.31
39%
-90
- C2 -
3R8F
4
DNAA_AQUAE
A:
[2-297]
------------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
-------
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
--
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
--
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
---
R
T
Q
-------
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
-
N
V
-
R
E
I
E
G
K
I
K
L
I
K
L
K
G
F
E
G
L
E
R
-----
K
E
--------------
R
K
E
R
D
K
L
M
Q
I
V
E
F
---
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
---
N
K
R
T
-
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
-----
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
--------------------------
5
PsiBlast_PDB
91.87
38%
-90
- C2 -
1L8Q
2
DNAA_AQUAE
A:
[2-296]
------------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
-------
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
--
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
--
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
---
R
T
Q
-------
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
-
N
V
-
R
E
I
E
G
K
I
K
L
I
K
L
K
G
F
E
G
L
E
R
-----
K
E
--------------
R
K
E
R
D
K
L
M
Q
I
V
E
F
---
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
--
R
N
K
R
T
-
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
-----
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
--------------------------
26
PsiBlast_CBE
90.65
39%
-85
- C2 -
2HCB
2
DNAA_AQUAE
D:
[1-295]
------------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
-------
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
--
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
--
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
---
R
T
Q
-------
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
-
N
V
-
R
E
I
E
G
KI
K
L
I
K
L
K
G
F
E
G
L
E
R
-----
K
E
--------------
R
K
E
R
D
K
L
M
Q
I
V
E
F
---
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
---
N
K
R
T
-
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
-----
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
--------------------------
27
PsiBlast_CBE
90.22
39%
-86
- C2 -
2HCB
3
DNAA_AQUAE
C:
[1-295]
------------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
-------
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
--
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
--
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
---
R
T
Q
-------
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
-
N
V
-
R
E
I
E
G
KI
K
L
I
K
L
K
G
F
E
G
L
E
R
-----
K
E
--------------
R
K
E
R
D
K
L
M
Q
I
V
E
F
---
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
---
N
K
R
T
-
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
-----
S
A
S
L
I
E
I
A
R
A
F
---
D
H
T
T
V
I
H
A
--------------------------
4
PsiBlast_PDB
90.02
39%
-91
- C2 -
2HCB
3
DNAA_AQUAE
A:
[1-295]
------------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
-------
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
--
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
--
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
---
R
T
Q
-------
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
-
N
V
-
R
E
I
E
G
K
I
K
L
I
K
L
K
G
F
E
G
L
E
R
-----
K
E
--------------
R
K
E
R
D
K
L
M
Q
I
V
E
F
---
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
--
R
--
R
T
-
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
-----
S
A
S
L
I
E
I
A
R
A
F
K
--
D
H
T
T
V
I
H
A
--------------------------
28
PsiBlast_CBE
89.88
39%
-86
- C2 -
2HCB
3
DNAA_AQUAE
B:
[1-295]
------------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
-------
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
--
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
--
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
---
R
T
Q
-------
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
-
N
V
-
R
E
I
E
G
K
I
K
L
I
K
L
K
G
F
E
G
L
E
R
-----
K
E
--------------
R
K
E
R
D
K
L
M
Q
I
V
E
F
---
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
---
N
K
R
T
-
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
-----
S
A
S
L
I
E
I
A
R
A
F
K
--
D
H
T
T
V
I
H
A
--------------------------
1
PsiBlast_PDB
89.66
37%
-106
- C2 -
2Z4R
2
DNAA_THEMA
A:
[96-335]
------------------------------------------------------------------------------------------------------
T
P
------
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
-------
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
D
L
R
V
M
Y
I
T
S
E
K
F
L
N
D
L
V
D
S
M
K
E
G
K
L
N
E
F
R
E
K
--
Y
-
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
---
G
V
Q
-------
T
E
L
F
H
T
F
N
E
L
H
D
S
--------
G
K
-
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
-
N
L
-
R
R
L
R
G
--
A
I
I
K
L
L
V
Y
K
E
T
T
G
-----
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
K
P
----------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
89.54
37%
-107
- C2 -
2Z4S
2
DNAA_THEMA
A:
[96-335]
------------------------------------------------------------------------------------------------------
T
P
------
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
-------
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
D
L
R
V
M
Y
I
T
S
E
K
F
L
N
D
L
V
D
S
M
K
E
G
K
L
N
E
F
R
E
K
--
Y
-
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
---
G
V
Q
-------
T
E
L
F
H
T
F
N
E
L
H
D
S
--------
G
K
-
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
-
N
L
-
R
R
L
R
G
--
A
I
I
K
L
L
V
Y
K
E
T
T
G
-----
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
K
P
----------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
89.42
37%
-106
- C2 -
2Z4R
2
DNAA_THEMA
B:
[96-335]
------------------------------------------------------------------------------------------------------
T
P
------
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
-------
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
D
L
R
V
M
Y
I
T
S
E
K
F
L
N
D
L
V
D
S
M
K
E
G
K
L
N
E
F
R
E
K
--
Y
-
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
---
G
V
Q
-------
T
E
L
F
H
T
F
N
E
L
H
D
S
--------
G
K
-
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
-
N
L
-
R
R
L
R
G
--
A
I
I
K
L
L
V
Y
K
E
T
T
G
-----
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
K
P
----------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
89.18
37%
-105
- C2 -
2Z4R
2
DNAA_THEMA
C:
[96-335]
------------------------------------------------------------------------------------------------------
T
P
------
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
-------
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
D
L
R
V
M
Y
I
T
S
E
K
F
L
N
D
L
V
D
S
M
K
E
G
K
L
N
E
F
R
E
K
--
Y
-
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
---
G
V
Q
-------
T
E
L
F
H
T
F
N
E
L
H
D
S
--------
G
K
-
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
-
N
L
-
R
R
L
R
G
--
A
I
I
K
L
L
V
Y
K
E
T
T
G
-----
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
K
P
----------------------------------------------------------------------------------------------------------
42
HHSearch
88.69
36%
-105
- C2 -
2Z4S
2
DNAA_THEMA
A:
[96-335]
------------------------------------------------------------------------------------------------------------
T
P
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
-------
G
-
R
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
D
L
R
V
M
Y
I
T
S
E
K
F
L
N
D
L
V
D
S
M
K
E
G
K
L
N
E
F
R
E
K
--
Y
-
R
K
K
-
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
---
G
V
Q
-------
T
E
L
F
H
T
F
N
E
L
H
D
S
--------
G
K
-
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
-
N
L
-
R
R
L
R
G
--
A
I
I
K
L
L
V
Y
K
E
T
T
G
-----
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
K
P
----------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
65.08
23%
-69
- C2 -
3SC3
2
?
A:
[14-224]
------------------------------------------------------------------------------------------------------------------------
Y
P
A
A
G
N
D
E
L
I
G
A
L
K
S
A
A
S
G
---------
D
G
V
Q
A
I
Y
L
W
G
P
V
K
S
G
R
T
H
L
I
H
A
---------
A
C
A
R
A
N
E
L
E
R
R
S
F
Y
I
P
L
--
G
I
H
A
S
I
S
T
A
L
L
E
G
--
L
-
E
-
Q
-
F
D
L
I
C
I
D
D
V
D
A
V
A
G
H
P
---
L
W
E
-------
E
A
I
F
D
L
Y
N
R
V
A
E
Q
--------
K
R
G
S
L
I
V
S
A
S
A
S
P
M
E
A
G
F
V
L
P
D
L
V
S
R
M
H
W
G
L
T
Y
Q
L
Q
P
M
M
D
D
E
K
L
A
A
L
Q
R
R
A
A
M
R
G
L
Q
L
P
E
D
V
G
R
F
L
L
N
R
M
A
R
-
D
L
-
R
T
L
F
D
--
V
L
D
R
L
D
K
A
S
M
V
H
Q
-----
R
K
L
T
I
P
F
V
K
E
M
L
R
---------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
64.92
100%
-102
- C1 -
4TPS
-
DNAA_BACSU
B:
[4-84]
M
E
N
I
L
D
L
W
N
Q
A
L
A
Q
I
E
K
K
L
S
K
P
S
F
E
T
W
M
K
S
T
K
A
H
S
L
Q
G
D
T
L
T
I
T
A
P
N
E
F
A
R
D
W
L
E
S
R
Y
L
H
L
I
A
D
T
I
Y
E
L
T
G
E
E
L
S
I
K
F
V
I
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
63.86
19%
-52
- C2 -
4WW0
2
FTSH_AQUAE
A:
[10-372]
-------------------------------------------------------------------------------------------------------------
E
E
K
P
K
V
T
F
K
D
V
A
G
I
E
E
V
K
E
E
V
K
E
I
I
E
Y
L
K
D
P
V
K
F
Q
K
L
G
G
R
P
P
K
G
V
L
L
Y
G
E
P
G
V
G
K
T
L
L
A
K
A
I
A
G
E
A
H
-----
V
P
F
I
S
V
S
G
S
D
F
V
E
M
F
V
G
V
G
A
A
R
V
R
D
L
F
E
T
A
--
K
K
H
-
A
-
P
C
M
I
F
I
D
E
I
D
A
V
G
R
--E
R
E
Q
T
L
-------
N
Q
L
L
V
E
M
D
G
F
D
T
S
--------
D
G
-
I
I
V
I
A
A
T
N
R
P
D
I
---
L
D
P
A
L
L
R
P
G
R
F
D
R
Q
I
F
I
P
K
P
D
V
R
G
R
Y
E
I
L
K
V
H
A
R
N
K
K
L
-
A
K
D
V
D
L
E
F
V
A
R
A
T
P
G
L
T
G
-
A
D
L
E
N
--
L
L
N
E
A
A
L
L
A
A
R
K
G
K----
E
E
I
T
M
E
E
I
E
E
A
L
D
R
I
T
M
-----
T
I
S
P
K
E
K
E
K
I
A
I
H
E
A
G
H
A
L
M
G
L
V
S
D
D
D
D
K
V
H
K
I
S
I
I
P
------------HIYD
K
K
D
L
Y
N
K
I
L
V
L
L
G
G
R
A
A
E
E
V
F
F
G
K
D
G
I
T
T
G
A
E
N
D
---------------
58
HHSearch
59.92
20%
-86
- C2 -
3PFI
1
RUVB_CAMJE
A:
[27-235]
-------------------------------------------------------------------------------------------------------------------
N
F
D
G
Y
I
G
Q
E
S
I
K
K
N
L
N
V
F
I
A
A
A
K
K
R
-------
N
E
C
L
D
H
I
L
F
S
G
P
A
G
L
G
K
T
T
L
A
N
I
I
S
Y
E
M
S
A
N
-----
I
K
T
T
A
A
P
M
I
E
K
--
S
G
-----
D
L
A
A
I
L
T
N
--
L
-
S
-
E
-
G
D
I
L
F
I
D
E
I
H
R
L
S
P
-----
A
I
E
-------
E
V
L
Y
P
A
M
E
D
Y
R
L
-A
Q
T
I
K
I
D
L
P
K
-
F
T
L
I
G
A
T
T
R
A
G
---
M
L
S
N
P
L
R
D
R
F
G
M
--
Q
F
R
L
E
F
Y
K
D
S
E
L
A
L
I
L
Q
K
A
A
L
K
L
N
K
T
C
E
E
K
A
A
L
E
I
A
K
R
S
R
S
-
T
P
-
R
I
A
L
R
--
L
L
K
R
V
R
D
F
A
D
------------------------------------------------------------------------------------------------------------------------------------
55
HHSearch
59.53
19%
-73
- C2 -
3B9P
1
A:
[54-288]
------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
G
L
L
L
F
G
P
P
G
N
G
K
T
L
L
A
R
A
V
A
T
E
C
S
-----
A
T
F
L
N
I
S
A
A
S
L
T
S
K
Y
V
G
D
G
E
K
L
-
V
R
A
L
F
A
V
A
R
H
-
M
-
Q
-
P
S
I
I
F
I
D
E
V
D
S
L
L
S
E
R
------EAS
R
R
L
K
T
E
F
L
V
E
F
D
G
L
P
-----------
R
-
I
V
V
L
A
A
T
N
R
P
Q
E
---
L
D
E
A
A
L
R
R
F
T
K
--
R
V
Y
V
S
L
P
D
E
Q
T
R
E
L
L
L
N
R
L
L
Q
K
Q
G
S
P
L
D
T
E
A
L
R
R
L
A
K
I
T
D
G
-
Y
S
G
S
D
L
T
A
--
L
A
K
D
A
A
L
E
P
I
R
E
L
NISAM
R
A
I
T
E
Q
D
F
H
S
S
L
K
R
I
R
R
S
V
A
P
Q
S
---------
L
-
N
S
-
Y
E
K
W
S
----------------------------------------------------------------------------------