@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA3723: (2016-02-20 )
MSLLFEPLSLRQITLPNRIAVSPMCQYSAQEGLANDWHLVHLGSRAVGGAGLVIVEATAVLPEGRITADDLGIWSDAHVEPLHRITRFIESQGAVAGVQLAHAGRKASTWRPWLGKHGSVPIGDGGWIPVAPSAIPFDPQHTTPEALSEAQIEALVQAFVRAAERSLAAGFKVAEVHAAHGYLLHQFLSPLSNQRRDQYGGCFENRIRLLLQVTAAVRKAWPQELPLFVRLSATDWVEDGWNPDETVELARHLKDLGVDLIDVSSGGTAANAEIPVGPGYQTEFAERVKKEAGIASGTVGMITEPVQAEHILRTGQADLILLARELLRDPYWPLHAADELRNEQMPWPPQYLRAAHRSTPPRKSLEMQ
Atome Classification :
(33 SA)
.........10........20........--30.--.-......-------.40........50........60.-----...-....70........80........90........100.....----------..-110....---...120.--......130...-...------.140....-------...150-....-...160.....-..170.......180.......190.....--..200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSLLFEPL
S
L
R
Q
ITLPNRIAV
S
P
M
C
Q
Y
S
A
--Q-E--G-LAND
W
H
-------
L
V
H
LGSRAVG
G
A
G
L
V
I
V
E
A
T
A
VLP-----EGR-ITADDLGIWSDA
H
V
E
P
L
H
R
I
T
R
F
I
E
SQGA
V
A
G
V
Q
L
AHAGRKA----------ST-WR
P
W
LGK---HGSVPIG--DGG
W
I
PVAPSAI-PFD------PQHT
T
P
E
A
-------
L
S
E
A
Q
I
-
E
A
L
V
-
Q
A
F
V
R
A
A
E
R
S
L
-AAG
F
K
V
A
E
V
H
A
A
H
G
Y
L
L
H
Q
F
L
S
P
L
S
N
Q
R
R
D
--QYG
G
C
F
E
N
R
I
R
L
L
L
Q
V
T
A
A
V
R
K
AWPQEL
P
L
F
V
R
LSATDWVEDGW
N
P
D
E
T
V
E
L
A
R
H
L
K
D
LGV
D
L
I
D
VSSGGTAANAEIPVGPGY
Q
T
E
F
A
E
R
V
K
K
E
AGIASGTV
G
M
ITEP
V
Q
A
E
H
I
L
RTGQ
A
D
L
I
L
L
A
R
E
L
L
RDPYWPL
H
A
A
D
E
LRNEQMPW
P
P
Q
Y
L
R
A
A
HRSTPPRKSLEMQ
22
PsiBlast_CBE
96.06
56%
-91
- C4 -
3HGJ
2
?
C:
[2-348]
-
A
L
L
F
T
P
L
E
L
G
G
L
R
L
K
N
R
L
A
M
S
P
M
C
Q
Y
S
A
--
T
L
E
--
G
-
E
V
T
D
W
H
-------
L
L
H
Y
P
T
R
A
L
G
G
V
G
L
I
L
V
E
A
T
A
V
E
P
-----
L
G
R
-
I
S
P
Y
D
L
G
I
W
S
E
D
H
L
P
G
L
K
E
L
A
R
R
I
R
E
A
G
A
V
P
G
I
Q
L
A
H
A
G
R
K
A
----------
G
T
-
A
R
P
W
------
E
G
G
K
P
L
G
-----
W
R
V
V
G
P
S
P
I
-
P
F
D
------
E
G
Y
P
V
P
E
P
-------
L
D
E
A
G
M
-
E
R
I
L
-
Q
A
F
V
E
G
A
R
R
A
L
-
R
A
G
F
Q
V
I
E
L
H
M
A
H
G
Y
L
L
S
S
F
L
S
P
L
S
N
Q
R
T
D
--
A
Y
G
G
S
L
E
N
R
M
R
F
P
L
Q
V
A
Q
A
V
R
E
V
V
P
R
E
L
P
L
F
V
R
V
S
A
T
D
W
G
E
G
G
W
S
L
E
D
T
L
A
F
A
R
R
L
K
E
L
G
V
D
L
L
D
C
S
S
G
G
V
V
L
R
V
R
I
P
L
A
P
G
F
Q
V
P
F
A
D
A
V
R
K
R
V
G
L
R
T
G
A
V
G
L
I
T
T
P
E
Q
A
E
T
L
L
Q
A
G
S
A
D
L
V
L
L
G
R
V
L
L
R
D
P
Y
F
P
L
R
A
A
K
A
L
-
G
V
A
P
E
V
P
P
Q
Y
Q
R
G
--------------
1
PsiBlast_PDB
95.73
56%
-95
- C4 -
3HF3
3
?
A:
[2-348]
-
A
L
L
F
T
P
L
E
L
G
G
L
R
L
K
N
R
L
A
M
S
P
M
C
Q
Y
S
A
--
T
L
E
--
G
-
E
V
T
D
W
H
-------
L
L
H
Y
P
T
R
A
L
G
G
V
G
L
I
L
V
E
A
T
A
V
E
P
-----
L
G
R
-
I
S
P
Y
D
L
G
I
W
S
E
D
H
L
P
G
L
K
E
L
A
R
R
I
R
E
A
G
A
V
P
G
I
Q
L
A
H
A
G
R
K
A
----------
G
T
-
A
R
P
W
------
E
G
G
K
P
L
G
-----
W
R
V
V
G
P
S
P
I
-
P
F
D
------
E
G
Y
P
V
P
E
P
-------
L
D
E
A
G
M
-
E
R
I
L
-
Q
A
F
V
E
G
A
R
R
A
L
-
R
A
G
F
Q
V
I
E
L
H
M
A
H
G
Y
L
L
S
S
F
L
S
P
L
S
N
Q
R
T
D
--
A
Y
G
G
S
L
E
N
R
M
R
F
P
L
Q
V
A
Q
A
V
R
E
V
V
P
R
E
L
P
L
F
V
R
V
S
A
T
D
W
G
E
G
G
W
S
L
E
D
T
L
A
F
A
R
R
L
K
E
L
G
V
D
L
L
D
C
S
S
G
G
V
V
L
R
V
R
I
P
L
A
P
G
F
Q
V
P
F
A
D
A
V
R
K
R
V
G
L
R
T
G
A
V
G
L
I
T
T
P
E
Q
A
E
T
L
L
Q
A
G
S
A
D
L
V
L
L
G
R
V
L
L
R
D
P
Y
F
P
L
R
A
A
K
A
L
-
G
V
A
P
E
V
P
P
Q
Y
Q
R
G
--------------
25
PsiBlast_CBE
95.63
56%
-93
- C4 -
3HF3
2
?
C:
[2-348]
-
A
L
L
F
T
P
L
E
L
G
G
L
R
L
K
N
R
L
A
M
S
P
M
C
Q
Y
S
A
--
T
L
E
--
G
-
E
V
T
D
W
H
-------
L
L
H
Y
P
T
R
A
L
G
G
V
G
L
I
L
V
E
A
T
A
V
E
P
-----
L
G
R
-
I
S
P
Y
D
L
G
I
W
S
E
D
H
L
P
G
L
K
E
L
A
R
R
I
R
E
A
G
A
V
P
G
I
Q
L
A
H
A
G
R
K
A
----------
G
T
-
A
R
P
W
------
E
G
G
K
P
L
G
-----
W
R
V
V
G
P
S
P
I
-
P
F
D
------
E
G
Y
P
V
P
E
P
-------
L
D
E
A
G
M
-
E
R
I
L
-
Q
A
F
V
E
G
A
R
R
A
L
-
R
A
G
F
Q
V
I
E
L
H
M
A
H
G
Y
L
L
S
S
F
L
S
P
L
S
N
Q
R
T
D
--
A
Y
G
G
S
L
E
N
R
M
R
F
P
L
Q
V
A
Q
A
V
R
E
V
V
P
R
E
L
P
L
F
V
R
V
S
A
T
D
W
G
E
G
G
W
S
L
E
D
T
L
A
F
A
R
R
L
K
E
L
G
V
D
L
L
D
C
S
S
G
G
V
V
L
R
V
R
I
P
L
A
P
G
F
Q
V
P
F
A
D
A
V
R
K
R
V
G
L
R
T
G
A
V
G
L
I
T
T
P
E
Q
A
E
T
L
L
Q
A
G
S
A
D
L
V
L
L
G
R
V
L
L
R
D
P
Y
F
P
L
R
A
A
K
A
L
-
G
V
A
P
E
V
P
P
Q
Y
Q
R
G
--------------
21
PsiBlast_CBE
95.58
56%
-94
- C4 -
3HGJ
4
?
D:
[2-348]
-
A
L
L
F
T
P
L
E
L
G
G
L
R
L
K
N
R
L
A
M
S
P
M
C
Q
Y
S
A
--
T
L
E
--
G
-
E
V
T
D
W
H
-------
L
L
H
Y
P
T
R
A
L
G
G
V
G
L
I
L
V
E
A
T
A
V
E
P
-----
L
G
R
-
I
S
P
Y
D
L
G
I
W
S
E
D
H
L
P
G
L
K
E
L
A
R
R
I
R
E
A
G
A
V
P
G
I
Q
L
A
H
A
G
R
K
A
----------
G
T
-
A
R
P
W
------
E
G
G
K
P
L
G
-----
W
R
V
V
G
P
S
P
I
-
P
F
D
------
E
G
Y
P
V
P
E
P
-------
L
D
E
A
G
M
-
E
R
I
L
-
Q
A
F
V
E
G
A
R
R
A
L
-
R
A
G
F
Q
V
I
E
L
H
M
A
H
G
Y
L
L
S
S
F
L
S
P
L
S
N
Q
R
T
D
--
A
Y
G
G
S
L
E
N
R
M
R
F
P
L
Q
V
A
Q
A
V
R
E
V
V
P
R
E
L
P
L
F
V
R
V
S
A
T
D
W
G
E
G
G
W
S
L
E
D
T
L
A
F
A
R
R
L
K
E
L
G
V
D
L
L
D
C
S
S
G
G
V
V
L
R
V
R
I
P
L
A
P
G
F
Q
V
P
F
A
D
A
V
R
K
R
V
G
L
R
T
G
A
V
G
L
I
T
T
P
E
Q
A
E
T
L
L
Q
A
G
S
A
D
L
V
L
L
G
R
V
L
L
R
D
P
Y
F
P
L
R
A
A
K
A
L
-
G
V
A
P
E
V
P
P
Q
Y
Q
R
G
--------------
23
PsiBlast_CBE
95.33
56%
-94
- C4 -
3HGJ
2
?
B:
[2-348]
-
A
L
L
F
T
P
L
E
L
G
G
L
R
L
K
N
R
L
A
M
S
P
M
C
Q
Y
S
A
--
T
L
E
--
G
-
E
V
T
D
W
H
-------
L
L
H
Y
P
T
R
A
L
G
G
V
G
L
I
L
V
E
A
T
A
V
E
P
-----
L
G
R
-
I
S
P
Y
D
L
G
I
W
S
E
D
H
L
P
G
L
K
E
L
A
R
R
I
R
E
A
G
A
V
P
G
I
Q
L
A
H
A
G
R
K
A
----------
G
T
-
A
R
P
W
------
E
G
G
K
P
L
G
-----
W
R
V
V
G
P
S
P
I
-
P
F
D
------
E
G
Y
P
V
P
E
P
-------
L
D
E
A
G
M
-
E
R
I
L
-
Q
A
F
V
E
G
A
R
R
A
L
-
R
A
G
F
Q
V
I
E
L
H
M
A
H
G
Y
L
L
S
S
F
L
S
P
L
S
N
Q
R
T
D
--
A
Y
G
G
S
L
E
N
R
M
R
F
P
L
Q
V
A
Q
A
V
R
E
V
V
P
R
E
L
P
L
F
V
R
V
S
A
T
D
W
G
E
G
G
W
S
L
E
D
T
L
A
F
A
R
R
L
K
E
L
G
V
D
L
L
D
C
S
S
G
G
V
V
L
R
V
R
I
P
L
A
P
G
F
Q
V
P
F
A
D
A
V
R
K
R
V
G
L
R
T
G
A
V
G
L
I
T
T
P
E
Q
A
E
T
L
L
Q
A
G
S
A
D
L
V
L
L
G
R
V
L
L
R
D
P
Y
F
P
L
R
A
A
K
A
L
-
G
V
A
P
E
V
P
P
Q
Y
Q
R
G
--------------
26
PsiBlast_CBE
95.25
56%
-92
- C4 -
3HF3
2
?
B:
[2-348]
-
A
L
L
F
T
P
L
E
L
G
G
L
R
L
K
N
R
L
A
M
S
P
M
C
Q
Y
S
A
--
T
L
E
--
G
-
E
V
T
D
W
H
-------
L
L
H
Y
P
T
R
A
L
G
G
V
G
L
I
L
V
E
A
T
A
V
E
P
-----
L
G
R
-
I
S
P
Y
D
L
G
I
W
S
E
D
H
L
P
G
L
K
E
L
A
R
R
I
R
E
A
G
A
V
P
G
I
Q
L
A
H
A
G
R
K
A
----------
G
T
-
A
R
P
W
------
E
G
G
K
P
L
G
-----
W
R
V
V
G
P
S
P
I
-
P
F
D
------
E
G
Y
P
V
P
E
P
-------
L
D
E
A
G
M
-
E
R
I
L
-
Q
A
F
V
E
G
A
R
R
A
L
-
R
A
G
F
Q
V
I
E
L
H
M
A
H
G
Y
L
L
S
S
F
L
S
P
L
S
N
Q
R
T
D
--
A
Y
G
G
S
L
E
N
R
M
R
F
P
L
Q
V
A
Q
A
V
R
E
V
V
P
R
E
L
P
L
F
V
R
V
S
A
T
D
W
G
E
G
G
W
S
L
E
D
T
L
A
F
A
R
R
L
K
E
L
G
V
D
L
L
D
C
S
S
G
G
V
V
L
R
V
R
I
P
L
A
P
G
F
Q
V
P
F
A
D
A
V
R
K
R
V
G
L
R
T
G
A
V
G
L
I
T
T
P
E
Q
A
E
T
L
L
Q
A
G
S
A
D
L
V
L
L
G
R
V
L
L
R
D
P
Y
F
P
L
R
A
A
K
A
L
-
G
V
A
P
E
V
P
P
Q
Y
Q
R
G
--------------
2
PsiBlast_PDB
95.09
56%
-92
- C4 -
3HGJ
4
?
A:
[2-348]
-
A
L
L
F
T
P
L
E
L
G
G
L
R
L
K
N
R
L
A
M
S
P
M
C
Q
Y
S
A
--
T
L
E
--
G
-
E
V
T
D
W
H
-------
L
L
H
Y
P
T
R
A
L
G
G
V
G
L
I
L
V
E
A
T
A
V
E
P
-----
L
G
R
-
I
S
P
Y
D
L
G
I
W
S
E
D
H
L
P
G
L
K
E
L
A
R
R
I
R
E
A
G
A
V
P
G
I
Q
L
A
H
A
G
R
K
A
----------
G
T
-
A
R
P
W
------
E
G
G
K
P
L
G
-----
W
R
V
V
G
P
S
P
I
-
P
F
D
------
E
G
Y
P
V
P
E
P
-------
L
D
E
A
G
M
-
E
R
I
L
-
Q
A
F
V
E
G
A
R
R
A
L
-
R
A
G
F
Q
V
I
E
L
H
M
A
H
G
Y
L
L
S
S
F
L
S
P
L
S
N
Q
R
T
D
--
A
Y
G
G
S
L
E
N
R
M
R
F
P
L
Q
V
A
Q
A
V
R
E
V
V
P
R
E
L
P
L
F
V
R
V
S
A
T
D
W
G
E
G
G
W
S
L
E
D
T
L
A
F
A
R
R
L
K
E
L
G
V
D
L
L
D
C
S
S
G
G
V
V
L
R
V
R
I
P
L
A
P
G
F
Q
V
P
F
A
D
A
V
R
K
R
V
G
L
R
T
G
A
V
G
L
I
T
T
P
E
Q
A
E
T
L
L
Q
A
G
S
A
D
L
V
L
L
G
R
V
L
L
R
D
P
Y
F
P
L
R
A
A
K
A
L
-
G
V
A
P
E
V
P
P
Q
Y
Q
R
G
--------------
90
HHSearch
95.00
58%
-90
- C4 -
3HGJ
4
?
A:
[2-347]
-
A
L
L
F
T
P
L
E
L
G
G
L
R
L
K
N
R
L
A
M
S
P
M
C
Q
Y
S
A
T-
L
-
E
--
G
-
E
V
T
D
W
H
-------
L
L
H
Y
P
T
R
A
L
G
G
V
G
L
I
L
V
E
A
T
A
V
E
P
-----
L
G
R
-
I
S
P
Y
D
L
G
I
W
S
E
D
H
L
P
G
L
K
E
L
A
R
R
I
R
E
A
G
A
V
P
G
I
Q
L
A
H
A
G
R
K
A
----------
G
T
-
A
R
P
W
E
G
G
-----
K
--
P
L
--
G
W
--
R
V
V
G
P
S
P
I
-
P
F
D
------
E
G
Y
P
V
P
E
P
-------
L
D
E
A
G
M
-
E
R
I
L
-
Q
A
F
V
E
G
A
R
R
A
L
-
R
A
G
F
Q
V
I
E
L
H
M
A
H
G
Y
L
L
S
S
F
L
S
P
L
S
N
Q
R
T
D
--
A
Y
G
G
S
L
E
N
R
M
R
F
P
L
Q
V
A
Q
A
V
R
E
V
V
P
R
E
L
P
L
F
V
R
V
S
A
T
D
W
G
E
G
G
W
S
L
E
D
T
L
A
F
A
R
R
L
K
E
L
G
V
D
L
L
D
C
S
S
G
G
V
V
L
R
V
R
I
P
L
A
P
G
F
Q
V
P
F
A
D
A
V
R
K
R
V
G
L
R
T
G
A
V
G
L
I
T
T
P
E
Q
A
E
T
L
L
Q
A
G
S
A
D
L
V
L
L
G
R
V
L
L
R
D
P
Y
F
P
L
R
A
A
K
A
L
-
G
V
A
P
E
V
P
P
Q
Y
Q
R
---------------
24
PsiBlast_CBE
94.55
56%
-93
- C4 -
3HF3
3
?
D:
[2-348]
-
A
L
L
F
T
P
L
E
L
G
G
L
R
L
K
N
R
L
A
M
S
P
M
C
Q
Y
S
A
--
T
L
E
--
G
-
E
V
T
D
W
H
-------
L
L
H
Y
P
T
R
A
L
G
G
V
G
L
I
L
V
E
A
T
A
V
E
P
-----
L
G
R
-
I
S
P
Y
D
L
G
I
W
S
E
D
H
L
P
G
L
K
E
L
A
R
R
I
R
E
A
G
A
V
P
G
I
Q
L
A
H
A
G
R
K
A
----------
G
T
-
A
R
P
W
------
E
G
G
K
P
L
G
-----
W
R
V
V
G
P
S
P
I
-
P
F
D
------
E
G
Y
P
V
P
E
P
-------
L
D
E
A
G
M
-
E
R
I
L
-
Q
A
F
V
E
G
A
R
R
A
L
-
R
A
G
F
Q
V
I
E
L
H
M
A
H
G
Y
L
L
S
S
F
L
S
P
L
S
N
Q
R
T
D
--
A
Y
G
G
S
L
E
N
R
M
R
F
P
L
Q
V
A
Q
A
V
R
E
V
V
P
R
E
L
P
L
F
V
R
V
S
A
T
D
W
G
E
G
G
W
S
L
E
D
T
L
A
F
A
R
R
L
K
E
L
G
V
D
L
L
D
C
S
S
G
G
V
V
L
R
V
R
I
P
L
A
P
G
F
Q
V
P
F
A
D
A
V
R
K
R
V
G
L
R
T
G
A
V
G
L
I
T
T
P
E
Q
A
E
T
L
L
Q
A
G
S
A
D
L
V
L
L
G
R
V
L
L
R
D
P
Y
F
P
L
R
A
A
K
A
L
-
G
V
A
P
E
V
P
P
Q
Y
Q
R
G
--------------
5
PsiBlast_PDB
93.63
49%
-102
- C4 -
3GR7
3
NAMA_GEOKA
A:
[3-337]
-
T
M
L
F
S
P
Y
T
I
R
G
L
T
L
K
N
R
I
V
M
S
P
M
C
M
Y
S
C
DT
K
-
D
--
G
-
A
V
R
T
W
H
-------
K
I
H
Y
P
A
R
A
V
G
Q
V
G
L
I
I
V
E
A
T
G
V
T
P
-----
Q
G
R
-
I
S
E
R
D
L
G
I
W
S
D
D
H
I
A
G
L
R
E
L
V
G
L
V
K
E
H
G
A
A
I
G
I
Q
L
A
H
A
G
R
K
S
----------
Q
---------------
V
P
------
G
E
I
-
I
A
P
S
A
V
-
P
F
D
------
D
S
S
P
T
P
K
E
-------
M
T
K
A
D
I
-
E
E
T
V
-
Q
A
F
Q
N
G
A
R
R
A
K
-
E
A
G
F
D
V
I
E
I
H
A
A
H
G
Y
L
I
N
E
F
L
S
P
L
S
N
R
R
Q
D
--
E
Y
G
G
S
P
E
N
R
Y
R
F
L
G
E
V
I
D
A
V
R
E
V
W
--
D
G
P
L
F
V
R
I
S
A
S
D
Y
H
P
D
G
L
T
A
K
D
Y
V
P
Y
A
K
R
M
K
E
Q
G
V
D
L
V
D
V
S
S
G
A
I
V
P
-
A
R
M
N
V
Y
P
G
Y
Q
V
P
F
A
E
L
I
R
R
E
A
D
I
P
T
G
A
V
G
L
I
T
S
G
W
Q
A
E
E
I
L
Q
N
G
R
A
D
L
V
F
L
G
R
E
L
L
R
N
P
Y
W
P
Y
A
A
A
R
E
L
-
G
A
K
I
S
A
P
V
Q
Y
E
R
G
--------------
34
PsiBlast_CBE
93.41
49%
-103
- C4 -
3GR7
3
NAMA_GEOKA
B:
[3-337]
-
T
M
L
F
S
P
Y
T
I
R
G
L
T
L
K
N
R
I
V
M
S
P
M
C
M
Y
S
C
DT
K
-
D
--
G
-
A
V
R
T
W
H
-------
K
I
H
Y
P
A
R
A
V
G
Q
V
G
L
I
I
V
E
A
T
G
V
T
P
-----
Q
G
R
-
I
S
E
R
D
L
G
I
W
S
D
D
H
I
A
G
L
R
E
L
V
G
L
V
K
E
H
G
A
A
I
G
I
Q
L
A
H
A
G
R
K
S
----------
Q
---------------
V
P
------
G
E
I
-
I
A
P
S
A
V
-
P
F
D
------
D
S
S
P
T
P
K
E
-------
M
T
K
A
D
I
-
E
E
T
V
-
Q
A
F
Q
N
G
A
R
R
A
K
-
E
A
G
F
D
V
I
E
I
H
A
A
H
G
Y
L
I
N
E
F
L
S
P
L
S
N
R
R
Q
D
--
E
Y
G
G
S
P
E
N
R
Y
R
F
L
G
E
V
I
D
A
V
R
E
V
W
--
D
G
P
L
F
V
R
I
S
A
S
D
Y
H
P
D
G
L
T
A
K
D
Y
V
P
Y
A
K
R
M
K
E
Q
G
V
D
L
V
D
V
S
S
G
A
I
V
P
-
A
R
M
N
V
Y
P
G
Y
Q
V
P
F
A
E
L
I
R
R
E
A
D
I
P
T
G
A
V
G
L
I
T
S
G
W
Q
A
E
E
I
L
Q
N
G
R
A
D
L
V
F
L
G
R
E
L
L
R
N
P
Y
W
P
Y
A
A
A
R
E
L
-
G
A
K
I
S
A
P
V
Q
Y
E
R
G
--------------
33
PsiBlast_CBE
92.93
49%
-99
- C4 -
3GR8
3
NAMA_GEOKA
B:
[3-337]
-
T
M
L
F
S
P
Y
T
I
R
G
L
T
L
K
N
R
I
V
M
S
P
M
C
M
Y
S
C
DT
K
-
D
--
G
-
A
V
R
T
W
H
-------
K
I
H
Y
P
A
R
A
V
G
Q
V
G
L
I
I
V
E
A
T
G
V
T
P
-----
Q
G
R
-
I
S
E
R
D
L
G
I
W
S
D
D
H
I
A
G
L
R
E
L
V
G
L
V
K
E
H
G
A
A
I
G
I
Q
L
A
H
A
G
R
K
S
----------
Q
---------------
V
P
------
G
E
I
-
I
A
P
S
A
V
-
P
F
D
------
D
S
S
P
T
P
K
E
-------
M
T
K
A
D
I
-
E
E
T
V
-
Q
A
F
Q
N
G
A
R
R
A
K
-
E
A
G
F
D
V
I
E
I
H
A
A
H
G
Y
L
I
N
E
F
L
S
P
L
S
N
R
R
Q
D
--
E
Y
G
G
S
P
E
N
R
Y
R
F
L
G
E
V
I
D
A
V
R
E
V
W
--
D
G
P
L
F
V
R
I
S
A
S
D
Y
H
P
D
G
L
T
A
K
D
Y
V
P
Y
A
K
R
M
K
E
Q
G
V
D
L
V
D
V
S
S
G
A
I
V
P
-
A
R
M
N
V
Y
P
G
Y
Q
V
P
F
A
E
L
I
R
R
E
A
D
I
P
T
G
A
V
G
L
I
T
S
G
W
Q
A
E
E
I
L
Q
N
G
R
A
D
L
V
F
L
G
R
E
L
L
R
N
P
Y
W
P
Y
A
A
A
R
E
L
-
G
A
K
I
S
A
P
V
Q
Y
E
R
G
--------------
87
HHSearch
92.57
51%
-96
- C4 -
3GR7
3
NAMA_GEOKA
A:
[2-340]
N
T
M
L
F
S
P
Y
T
I
R
G
L
T
L
K
N
R
I
V
M
S
P
M
C
M
Y
S
C
DT
K
-
D
--
G
-
A
V
R
T
W
H
-------
K
I
H
Y
P
A
R
A
V
G
Q
V
G
L
I
I
V
E
A
T
G
V
T
P
-----
Q
G
R
-
I
S
E
R
D
L
G
I
W
S
D
D
H
I
A
G
L
R
E
L
V
G
L
V
K
E
H
G
A
A
I
G
I
Q
L
A
H
A
G
R
K
S
----------
Q
V
-
P
G
---------------------
E
I
I
A
P
S
A
V
-
P
F
D
------
D
S
S
P
T
P
K
E
-------
M
T
K
A
D
I
-
E
E
T
V
-
Q
A
F
Q
N
G
A
R
R
A
K
-
E
A
G
F
D
V
I
E
I
H
A
A
H
G
Y
L
I
N
E
F
L
S
P
L
S
N
R
R
Q
D
--
E
Y
G
G
S
P
E
N
R
Y
R
F
L
G
E
V
I
D
A
V
R
E
V
W
--
D
G
P
L
F
V
R
I
S
A
S
D
Y
H
P
D
G
L
T
A
K
D
Y
V
P
Y
A
K
R
M
K
E
Q
G
V
D
L
V
D
V
S
S
G
A
I
V
P
A
R
M
-
N
V
Y
P
G
Y
Q
V
P
F
A
E
L
I
R
R
E
A
D
I
P
T
G
A
V
G
L
I
T
S
G
W
Q
A
E
E
I
L
Q
N
G
R
A
D
L
V
F
L
G
R
E
L
L
R
N
P
Y
W
P
Y
A
A
A
R
E
L
-
G
A
K
I
S
A
P
V
Q
Y
E
R
G
W
R
F
-----------
6
PsiBlast_PDB
92.32
49%
-99
- C4 -
3GR8
4
NAMA_GEOKA
A:
[3-337]
-
T
M
L
F
S
P
Y
T
I
R
G
L
T
L
K
N
R
I
V
M
S
P
M
C
M
Y
S
C
DT
K
-
D
--
G
-
A
V
R
T
W
H
-------
K
I
H
Y
P
A
R
A
V
G
Q
V
G
L
I
I
V
E
A
T
G
V
T
P
-----
Q
G
R
-
I
S
E
R
D
L
G
I
W
S
D
D
H
I
A
G
L
R
E
L
V
G
L
V
K
E
H
G
A
A
I
G
I
Q
L
A
H
A
G
R
K
S
----------
Q
---------------
V
P
------
G
E
I
-
I
A
P
S
A
V
-
P
F
D
------
D
S
S
P
T
P
K
E
-------
M
T
K
A
D
I
-
E
E
T
V
-
Q
A
F
Q
N
G
A
R
R
A
K
-
E
A
G
F
D
V
I
E
I
H
A
A
H
G
Y
L
I
N
E
F
L
S
P
L
S
N
R
R
Q
D
--
E
Y
G
G
S
P
E
N
R
Y
R
F
L
G
E
V
I
D
A
V
R
E
V
W
--
D
G
P
L
F
V
R
I
S
A
S
D
Y
H
P
D
G
L
T
A
K
D
Y
V
P
Y
A
K
R
M
K
E
Q
G
V
D
L
V
D
V
S
S
G
A
I
V
P
-
A
R
M
N
V
Y
P
G
Y
Q
V
P
F
A
E
L
I
R
R
E
A
D
I
P
T
G
A
V
G
L
I
T
S
G
W
Q
A
E
E
I
L
Q
N
G
R
A
D
L
V
F
L
G
R
E
L
L
R
N
P
Y
W
P
Y
A
A
A
R
E
L
-
G
A
K
I
S
A
P
V
Q
Y
E
R
G
--------------
4
PsiBlast_PDB
91.30
48%
-98
- C4 -
3KRZ
3
?
A:
[2-336]
-
S
I
L
H
M
P
L
K
I
K
D
I
T
I
K
N
R
I
M
M
S
P
M
C
M
Y
S
A
--
S
T
D
--
G
-
M
P
N
D
W
H
-------
I
V
H
Y
A
T
R
A
I
G
G
V
G
L
I
M
Q
E
A
T
A
V
E
S
-----
R
G
R
-
I
T
D
H
D
L
G
I
W
N
D
E
Q
V
K
E
L
K
K
I
V
D
I
C
K
A
N
G
A
V
M
G
I
Q
L
A
H
A
G
R
K
C
----------
N
---------------
I
S
Y
E
--
D
----
V
V
G
P
S
P
I
-
K
A
G
------
D
R
Y
K
L
P
R
E
-------
L
S
V
E
E
I
-
K
S
I
V
-
K
A
F
G
E
A
A
K
R
A
N
-
L
A
G
Y
D
V
V
E
I
H
A
A
H
G
Y
L
I
H
E
F
L
S
P
L
S
N
K
R
K
D
--
E
Y
G
N
S
I
E
N
R
A
R
F
L
I
E
V
I
D
E
V
R
K
N
W
P
E
N
K
P
I
F
V
R
V
S
A
D
D
Y
M
E
G
G
I
N
I
D
M
M
V
E
Y
I
N
M
I
K
D
-
K
V
D
L
I
D
V
S
S
G
G
L
-
L
N
V
D
I
N
L
Y
P
G
Y
Q
V
K
Y
A
E
T
I
K
K
R
C
N
I
K
T
S
A
V
G
L
I
T
T
Q
E
L
A
E
E
I
L
S
N
E
R
A
D
L
V
A
L
G
R
E
L
L
R
N
P
Y
W
V
L
H
T
Y
----
T
S
K
E
D
W
P
K
Q
Y
E
R
A
F
K
------------
3
PsiBlast_PDB
91.09
48%
-97
- C4 -
3KRU
3
?
A:
[2-336]
-
S
I
L
H
M
P
L
K
I
K
D
I
T
I
K
N
R
I
M
M
S
P
M
C
M
Y
S
A
--
S
T
D
--
G
-
M
P
N
D
W
H
-------
I
V
H
Y
A
T
R
A
I
G
G
V
G
L
I
M
Q
E
A
T
A
V
E
S
-----
R
G
R
-
I
T
D
H
D
L
G
I
W
N
D
E
Q
V
K
E
L
K
K
I
V
D
I
C
K
A
N
G
A
V
M
G
I
Q
L
A
H
A
G
R
K
C
----------
N
---------------
I
S
Y
E
--
D
----
V
V
G
P
S
P
I
-
K
A
G
------
D
R
Y
K
L
P
R
E
-------
L
S
V
E
E
I
-
K
S
I
V
-
K
A
F
G
E
A
A
K
R
A
N
-
L
A
G
Y
D
V
V
E
I
H
A
A
H
G
Y
L
I
H
E
F
L
S
P
L
S
N
K
R
K
D
--
E
Y
G
N
S
I
E
N
R
A
R
F
L
I
E
V
I
D
E
V
R
K
N
W
P
E
N
K
P
I
F
V
R
V
S
A
D
D
Y
M
E
G
G
I
N
I
D
M
M
V
E
Y
I
N
M
I
K
D
-
K
V
D
L
I
D
V
S
S
G
G
L
-
L
N
V
D
I
N
L
Y
P
G
Y
Q
V
K
Y
A
E
T
I
K
K
R
C
N
I
K
T
S
A
V
G
L
I
T
T
Q
E
L
A
E
E
I
L
S
N
E
R
A
D
L
V
A
L
G
R
E
L
L
R
N
P
Y
W
V
L
H
T
Y
----
T
S
K
E
D
W
P
K
Q
Y
E
R
A
F
K
------------
32
PsiBlast_CBE
90.90
48%
-97
- C4 -
3KRU
3
?
B:
[2-336]
-
S
I
L
H
M
P
L
K
I
K
D
I
T
I
K
N
R
I
M
M
S
P
M
C
M
Y
S
A
--
S
T
D
--
G
-
M
P
N
D
W
H
-------
I
V
H
Y
A
T
R
A
I
G
G
V
G
L
I
M
Q
E
A
T
A
V
E
S
-----
R
G
R
-
I
T
D
H
D
L
G
I
W
N
D
E
Q
V
K
E
L
K
K
I
V
D
I
C
K
A
N
G
A
V
M
G
I
Q
L
A
H
A
G
R
K
C
----------
N
---------------
I
S
Y
E
--
D
----
V
V
G
P
S
P
I
-
K
A
G
------
D
R
Y
K
L
P
R
E
-------
L
S
V
E
E
I
-
K
S
I
V
-
K
A
F
G
E
A
A
K
R
A
N
-
L
A
G
Y
D
V
V
E
I
H
A
A
H
G
Y
L
I
H
E
F
L
S
P
L
S
N
K
R
K
D
--
E
Y
G
N
S
I
E
N
R
A
R
F
L
I
E
V
I
D
E
V
R
K
N
W
P
E
N
K
P
I
F
V
R
V
S
A
D
D
Y
M
E
G
G
I
N
I
D
M
M
V
E
Y
I
N
M
I
K
D
-
K
V
D
L
I
D
V
S
S
G
G
L
-
L
N
V
D
I
N
L
Y
P
G
Y
Q
V
K
Y
A
E
T
I
K
K
R
C
N
I
K
T
S
A
V
G
L
I
T
T
Q
E
L
A
E
E
I
L
S
N
E
R
A
D
L
V
A
L
G
R
E
L
L
R
N
P
Y
W
V
L
H
T
Y
----
T
S
K
E
D
W
P
K
Q
Y
E
R
A
F
K
------------
8
PsiBlast_PDB
90.76
47%
-100
- C4 -
1Z42
5
NAMA_BACSU
A:
[5-336]
---
L
F
T
P
I
T
I
K
D
M
T
L
K
N
R
I
V
M
S
P
M
C
M
Y
S
S
--
H
-
E
KD
G
-
K
L
T
P
F
H
-------
M
A
H
Y
I
S
R
A
I
G
Q
V
G
L
I
I
V
E
A
S
A
V
N
P
-----
Q
G
R
-
I
T
D
Q
D
L
G
I
W
S
D
E
H
I
E
G
F
A
K
L
T
E
Q
V
K
E
Q
G
S
K
I
G
I
Q
L
A
H
A
G
R
K
A
----------
E
L
-----------
E
G
D
I
-----------
F
A
P
S
A
I
-
A
F
D
------
E
Q
S
A
T
P
V
E
-------
M
S
A
E
K
V
-
K
E
T
V
-
Q
E
F
K
Q
A
A
A
R
A
K
-
E
A
G
F
D
V
I
E
I
H
A
A
H
G
Y
L
I
H
E
F
L
S
P
L
S
N
H
R
T
D
--
E
Y
G
G
S
P
E
N
R
Y
R
F
L
R
E
I
I
D
E
V
K
Q
V
W
--
D
G
P
L
F
V
R
V
S
A
S
D
Y
T
D
K
G
L
D
I
A
D
H
I
G
F
A
K
W
M
K
E
Q
G
V
D
L
I
D
C
S
S
G
A
L
-
V
H
A
D
I
N
V
F
P
G
Y
Q
V
S
F
A
E
K
I
R
E
Q
A
D
M
A
T
G
A
V
G
M
I
T
D
G
S
M
A
E
E
I
L
Q
N
G
R
A
D
L
I
F
I
G
R
E
L
L
R
D
P
F
F
A
R
T
A
A
K
Q
L
-
N
T
E
I
P
A
P
V
Q
Y
E
R
---------------
9
PsiBlast_PDB
90.71
47%
-99
- C4 -
1Z44
7
NAMA_BACSU
A:
[5-336]
---
L
F
T
P
I
T
I
K
D
M
T
L
K
N
R
I
V
M
S
P
M
C
M
Y
S
S
--
H
-
E
KD
G
-
K
L
T
P
F
H
-------
M
A
H
Y
I
S
R
A
I
G
Q
V
G
L
I
I
V
E
A
S
A
V
N
P
-----
Q
G
R
-
I
T
D
Q
D
L
G
I
W
S
D
E
H
I
E
G
F
A
K
L
T
E
Q
V
K
E
Q
G
S
K
I
G
I
Q
L
A
H
A
G
R
K
A
----------
E
L
-----------
E
G
D
I
-----------
F
A
P
S
A
I
-
A
F
D
------
E
Q
S
A
T
P
V
E
-------
M
S
A
E
K
V
-
K
E
T
V
-
Q
E
F
K
Q
A
A
A
R
A
K
-
E
A
G
F
D
V
I
E
I
H
A
A
H
G
Y
L
I
H
E
F
L
S
P
L
S
N
H
R
T
D
--
E
Y
G
G
S
P
E
N
R
Y
R
F
L
R
E
I
I
D
E
V
K
Q
V
W
--
D
G
P
L
F
V
R
V
S
A
S
D
Y
T
D
K
G
L
D
I
A
D
H
I
G
F
A
K
W
M
K
E
Q
G
V
D
L
I
D
C
S
S
G
A
L
-
V
H
A
D
I
N
V
F
P
G
Y
Q
V
S
F
A
E
K
I
R
E
Q
A
D
M
A
T
G
A
V
G
M
I
T
D
G
S
M
A
E
E
I
L
Q
N
G
R
A
D
L
I
F
I
G
R
E
L
L
R
D
P
F
F
A
R
T
A
A
K
Q
L
-
N
T
E
I
P
A
P
V
Q
Y
E
R
---------------
29
PsiBlast_CBE
90.63
48%
-99
- C4 -
3KRZ
2
?
B:
[3-336]
--
I
L
H
M
P
L
K
I
K
D
I
T
I
K
N
R
I
M
M
S
P
M
C
M
Y
S
A
--
S
T
D
--
G
-
M
P
N
D
W
H
-------
I
V
H
Y
A
T
R
A
I
G
G
V
G
L
I
M
Q
E
A
T
A
V
E
S
-----
R
G
R
-
I
T
D
H
D
L
G
I
W
N
D
E
Q
V
K
E
L
K
K
I
V
D
I
C
K
A
N
G
A
V
M
G
I
Q
L
A
H
A
G
R
K
C
----------
N
---------------
I
S
Y
E
--
D
----
V
V
G
P
S
P
I
-
K
A
G
------
D
R
Y
K
L
P
R
E
-------
L
S
V
E
E
I
-
K
S
I
V
-
K
A
F
G
E
A
A
K
R
A
N
-
L
A
G
Y
D
V
V
E
I
H
A
A
H
G
Y
L
I
H
E
F
L
S
P
L
S
N
K
R
K
D
--
E
Y
G
N
S
I
E
N
R
A
R
F
L
I
E
V
I
D
E
V
R
K
N
W
P
E
N
K
P
I
F
V
R
V
S
A
D
D
Y
M
E
G
G
I
N
I
D
M
M
V
E
Y
I
N
M
I
K
D
-
K
V
D
L
I
D
V
S
S
G
G
L
-
L
N
V
D
I
N
L
Y
P
G
Y
Q
V
K
Y
A
E
T
I
K
K
R
C
N
I
K
T
S
A
V
G
L
I
T
T
Q
E
L
A
E
E
I
L
S
N
E
R
A
D
L
V
A
L
G
R
E
L
L
R
N
P
Y
W
V
L
H
T
Y
----
T
S
K
E
D
W
P
K
Q
Y
E
R
A
F
K
------------
88
HHSearch
90.39
50%
-93
- C4 -
1Z41
5
NAMA_BACSU
A:
[2-338]
A
R
K
L
F
T
P
I
T
I
K
D
M
T
L
K
N
R
I
V
M
S
P
M
C
M
Y
S
S
HE
K
-
D
--
G
-
K
L
T
P
F
H
-------
M
A
H
Y
I
S
R
A
I
G
Q
V
G
L
I
I
V
E
A
S
A
V
N
P
-----
Q
G
R
-
I
T
D
Q
D
L
G
I
W
S
D
E
H
I
E
G
F
A
K
L
T
E
Q
V
K
E
Q
G
S
K
I
G
I
Q
L
A
H
A
G
R
K
A
----------
E
L
-
E
G
-------------------
D
--
I
F
A
P
S
A
I
-
A
F
D
------
E
Q
S
A
T
P
V
E
-------
M
S
A
E
K
V
-
K
E
T
V
-
Q
E
F
K
Q
A
A
A
R
A
K
-
E
A
G
F
D
V
I
E
I
H
A
A
H
G
Y
L
I
H
E
F
L
S
P
L
S
N
H
R
T
D
--
E
Y
G
G
S
P
E
N
R
Y
R
F
L
R
E
I
I
D
E
V
K
Q
V
W
--
D
G
P
L
F
V
R
V
S
A
S
D
Y
T
D
K
G
L
D
I
A
D
H
I
G
F
A
K
W
M
K
E
Q
G
V
D
L
I
D
C
S
S
G
A
L
V
H
A
D
-
I
N
V
F
P
G
Y
Q
V
S
F
A
E
K
I
R
E
Q
A
D
M
A
T
G
A
V
G
M
I
T
D
G
S
M
A
E
E
I
L
Q
N
G
R
A
D
L
I
F
I
G
R
E
L
L
R
D
P
F
F
A
R
T
A
A
K
Q
L
-
N
T
E
I
P
A
P
V
Q
Y
E
R
G
W
-------------
69
PsiBlast_CBE
57.79
31%
-86
- C4 -
2G5W
2
OPR3_ARATH
A:
[12-246]
---
L
F
S
S
Y
K
M
G
R
F
D
L
S
H
R
V
V
L
A
P
M
T
R
C
R
A
--
L
-
N
--
G
-
V
P
N
A
A
L
-------
A
E
Y
Y
A
Q
R
T
T
P
G
-
G
F
L
I
S
E
G
T
M
V
S
P
-----
G
S
A
-
G
F
P
H
V
P
G
I
Y
S
D
E
Q
V
E
A
W
K
Q
V
V
E
A
V
H
A
K
G
G
F
I
F
C
Q
L
W
H
V
G
R
A
S
H---------
A
V
-
Y
Q
P
N
G
G
S
P
I
S
S
T
N
K
P
I
S
--
E
N
R
W
R
V
L
L
P
D
G
S
-
H
V
--------
K
Y
P
K
P
R
A
-------
L
E
A
S
E
I
-
P
R
V
V
-
E
D
Y
C
L
S
A
L
N
A
I
-
R
A
G
F
D
G
I
E
I
H
G
A
H
G
Y
L
I
D
Q
F
L
K
D
G
I
N
D
R
T
D
--
Q
Y
G
G
S
I
A
N
R
C
R
F
L
K
Q
V
V
E
G
V
V
S
A
----------------------------------------------------------------------------------------------------------------------------------------------------
82
PsiBlast_CBE
57.73
31%
-83
- C4 -
4E2B
6
?
A:
[10-243]
---
L
L
R
P
L
K
L
G
R
Y
T
L
R
N
R
I
I
M
A
P
L
T
R
C
Q
A
--
T
-
E
-------
D
G
H
VPRT
E
S
M
L
K
Y
Y
E
D
R
A
--
S
A
G
L
I
I
A
E
A
T
M
V
Q
P
-----
N
Y
T
-
G
F
L
T
E
P
G
I
Y
S
D
A
Q
I
E
E
W
R
K
I
V
D
A
V
H
K
K
G
G
L
I
F
L
Q
L
I
H
A
G
R
A
G
I
P
E
K
I
L
Q
QPK
S
D
-
Q
D
P
L
A
G
R
LLA
A
S
A
I
P
I
K
--
D
-
H
R
I
P
A
Y
F
A
A
S
-
G
E
K
------
E
T
Y
G
V
P
E
E
-------
L
T
D
D
E
V
R
N
G
I
I
-
P
L
F
V
E
G
A
K
N
A
I
F
K
A
G
F
D
G
V
E
I
H
G
A
N
G
Y
L
L
D
A
F
F
R
E
S
S
N
K
R
Q
S
GP
Y
A
G
T
T
I
D
T
R
C
Q
L
I
Y
D
V
T
K
S
V
C
D
A
----------------------------------------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
56.76
31%
-89
- C4 -
2G5W
2
OPR3_ARATH
B:
[12-240]
---
L
F
S
S
Y
K
M
G
R
F
D
L
S
H
R
V
V
L
A
P
M
T
R
C
R
A
--
L
-
N
--
G
-
V
P
N
A
A
L
-------
A
E
Y
Y
A
Q
R
T
T
P
G
-
G
F
L
I
S
E
G
T
M
V
S
P
-----
G
S
A
-
G
F
P
H
V
P
G
I
Y
S
D
E
Q
V
E
A
W
K
Q
V
V
E
A
V
H
A
K
G
G
F
I
F
C
Q
L
W
H
V
G
R
A
S
H---------
A
V
-
Y
Q
P
N
G
G
S
PIS
S
T
N
K
P
I
S
--
E
N
R
W
R
V
L
L
P
D
G
S
-
H
V
--------
K
Y
P
K
P
R
A
-------
L
E
A
S
E
I
-
P
R
V
V
-
E
D
Y
C
L
S
A
L
N
A
I
-
R
A
G
F
D
G
I
E
I
H
G
A
H
G
Y
L
I
D
Q
F
L
K
D
G
I
N
D
R
T
D
--
Q
Y
G
G
S
I
A
N
R
C
R
F
L
K
Q
V
V
E
G
V
V
S
A
----------------------------------------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
56.50
31%
-85
- C4 -
3HGR
2
OPR1_SOLLC
B:
[16-237]
---
L
M
S
P
C
K
M
G
K
F
E
L
C
H
R
V
V
L
A
P
L
T
R
Q
R
S
--
Y
-
G
--
Y
-
I
P
Q
P
H
A
-------
I
L
H
Y
S
Q
R
S
T
N
G
-
G
L
L
I
G
E
A
T
V
I
S
E
-----
T
G
I
-
G
Y
K
D
V
P
G
I
W
T
K
E
Q
V
E
A
W
K
P
I
V
D
A
V
H
A
K
G
G
I
F
F
C
Q
I
W
H
V
G
R
V
S
----------
N
K
D
F
Q
P
-------
N
G
E
D
P
I
S
CT
D
R
G
L
T
P
Q
I
M
S
N
G
-
I
D
I
------
A
H
F
T
R
P
R
R
-------
L
T
T
D
E
I
-
P
Q
I
V
-
N
E
F
R
V
A
A
R
N
A
I
-
E
A
G
F
D
G
V
E
I
H
G
A
H
G
Y
L
I
D
Q
F
M
K
D
Q
V
N
D
R
S
D
--
K
Y
G
G
S
L
E
N
R
C
R
F
A
L
E
I
V
E
A
V
-------------------------------------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
55.33
31%
-83
- C4 -
3HGR
2
OPR1_SOLLC
A:
[16-237]
---
L
M
S
P
C
K
M
G
K
F
E
L
C
H
R
V
V
L
A
P
L
T
R
Q
R
S
--
Y
-
G
--
Y
-
I
P
Q
P
H
A
-------
I
L
H
Y
S
Q
R
S
T
N
G
-
G
L
L
I
G
E
A
T
V
I
S
E
-----
T
G
I
-
G
Y
K
D
V
P
G
I
W
T
K
E
Q
V
E
A
W
K
P
I
V
D
A
V
H
A
K
G
G
I
F
F
C
Q
I
W
H
V
G
R
V
S
----------
N
K
D
F
Q
P
-------
N
G
E
D
P
I
S
CT
D
R
G
L
T
P
Q
I
M
S
N
G
-
I
D
I
------
A
H
F
T
R
P
R
R
-------
L
T
T
D
E
I
-
P
Q
I
V
-
N
E
F
R
V
A
A
R
N
A
I
-
E
A
G
F
D
G
V
E
I
H
G
A
H
G
Y
L
I
D
Q
F
M
K
D
Q
V
N
D
R
S
D
--
K
Y
G
G
S
L
E
N
R
C
R
F
A
L
E
I
V
E
A
V
-------------------------------------------------------------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
55.11
33%
-74
- C4 -
4JIC
2
?
A:
[2-218]
-
T
S
L
F
E
P
A
Q
A
G
D
I
A
L
A
N
R
I
V
M
A
P
L
T
R
N
R
S
--
P
-
G
--
A
-
I
P
N
N
L
N
-------
A
T
Y
Y
E
Q
R
A
T
--
A
G
L
I
V
T
E
G
T
P
I
S
Q
-----
Q
G
Q
-
G
Y
A
D
V
P
G
L
Y
K
R
E
A
I
E
G
W
K
K
I
T
D
G
V
H
S
A
G
G
K
I
V
A
Q
I
W
H
V
G
R
I
S
----------
H
T
-
S
---
L
Q
P
---
H
G
G
Q
P
V
A
--
P
S
A
I
T
A
K
S
K
T
Y
I
-
I
N
D
D
G
T
G
A
F
A
E
T
S
E
P
R
A
-------
L
T
I
D
D
I
-
G
L
I
L
-
E
D
Y
R
S
G
A
R
A
A
L
-
E
A
G
F
D
G
V
E
I
H
A
A
N
G
Y
L
I
E
Q
F
L
K
S
S
T
N
Q
R
T
D
--
D
Y
G
G
S
I
E
N
R
A
R
F
L
L
E
V
V
D
A
V
-------------------------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
53.93
34%
-84
- C4 -
3TJL
6
?
A:
[15-224]
----
F
Q
S
I
K
V
G
N
N
T
L
Q
T
K
I
V
Y
P
P
T
T
R
F
R
A
--
L
-
E
--
D
H
T
P
S
D
L
Q
-------
L
Q
Y
Y
G
D
R
S
T
F
P
G
T
L
L
I
T
E
A
T
F
V
S
P
-----
Q
A
S
G
Y
E
G
A
A
P
G
I
W
T
D
K
H
A
K
A
W
K
V
I
T
D
K
V
H
A
N
G
S
F
V
S
T
Q
L
I
F
L
G
R
V
A
----------
D
----
P
A
V
M
K
---
T
R
---------
G
L
N
P
V
S
A
S
A
T
Y
E
S
D
------
A
A
K
E
A
A
E
A
V
GN
P
V
R
A
L
T
T
Q
E
V
-
K
D
L
V
Y
E
A
Y
T
N
A
A
Q
K
A
M
-
D
A
G
F
D
Y
I
E
L
H
A
A
H
G
Y
L
L
D
Q
F
L
Q
P
C
T
N
Q
R
T
D
--
E
Y
G
G
S
I
E
N
R
A
R
L
I
L
E
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
53.72
34%
-83
- C4 -
4DF2
4
?
A:
[15-224]
----
F
Q
S
I
K
V
G
N
N
T
L
Q
T
K
I
V
Y
P
P
T
T
R
F
R
A
--
L
-
E
--
D
H
T
P
S
D
L
Q
-------
L
Q
Y
Y
G
D
R
S
T
F
P
G
T
L
L
I
T
E
A
T
F
V
S
P
-----
Q
A
S
G
Y
E
G
A
A
P
G
I
W
T
D
K
H
A
K
A
W
K
V
I
T
D
K
V
H
A
N
G
S
F
V
S
T
Q
L
I
F
L
G
R
V
A
----------
D
----
P
A
V
M
K
---
T
R
---------
G
L
N
P
V
S
A
S
A
T
Y
E
S
D
------
A
A
K
E
A
A
E
A
V
GN
P
V
R
A
L
T
T
Q
E
V
-
K
D
L
V
Y
E
T
Y
T
N
A
A
Q
K
A
M
-
D
A
G
F
D
Y
I
E
L
H
A
A
H
G
Y
L
L
D
Q
F
L
Q
P
C
T
N
Q
R
T
D
--
E
Y
G
G
S
I
E
N
R
A
R
L
I
L
E
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
52.05
34%
-82
- C4 -
3UPW
6
?
A:
[15-224]
----
F
Q
S
I
K
V
G
N
N
T
L
Q
T
K
I
V
Y
P
P
T
T
R
F
R
A
--
L
-
E
--
D
H
T
P
S
D
L
Q
-------
L
Q
Y
Y
G
D
R
S
T
F
P
G
T
L
L
I
T
E
A
T
F
V
S
P
-----
Q
A
S
G
Y
E
G
A
A
P
G
I
W
T
D
K
H
A
K
A
W
K
V
I
T
D
K
V
H
A
N
G
S
F
V
S
T
Q
L
I
F
L
G
R
V
A
----------
D
----
P
A
V
M
K
---
T
R
---------
G
L
N
P
V
S
A
S
A
T
Y
E
S
D
------
A
A
K
E
A
A
E
A
V
GN
P
V
R
A
L
T
T
Q
E
V
-
K
D
L
V
Y
E
A
Y
T
N
A
A
Q
K
A
M
-
D
A
G
F
D
Y
I
E
L
H
A
A
H
G
Y
L
L
D
Q
F
L
Q
P
C
T
N
Q
R
T
D
--
E
Y
G
G
S
I
E
N
R
A
R
L
I
L
E
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
51.61
33%
-73
- C4 -
4M5P
4
?
A:
[15-224]
----
F
Q
S
I
K
V
G
N
N
T
L
Q
T
K
I
V
Y
P
P
T
T
R
F
R
A
--
L
-
E
--
D
H
T
P
S
D
L
Q
-------
L
Q
Y
Y
G
D
R
S
T
F
P
G
T
L
L
I
T
E
A
T
F
V
S
P
QASGW
E
G
A
-
A
P
----
G
I
W
T
D
K
H
A
K
A
W
K
V
I
T
D
K
V
H
A
N
G
S
F
V
S
T
Q
L
C
F
L
G
R
V
A
----------
D
----
P
A
V
M
K
T
--
R
G
L
N
P
V
S
--
A
S
A
T
Y
E
S
D
A
A
K
E
-
A
A
E
------
A
V
G
N
P
V
R
A
-------
L
T
T
Q
E
V
-
K
D
L
V
Y
E
A
Y
T
N
A
A
Q
K
A
M
-
D
A
G
F
D
Y
I
E
L
H
A
A
H
G
Y
L
L
D
Q
F
L
Q
P
C
T
N
Q
R
T
D
--
E
Y
G
G
S
I
E
N
R
A
R
L
I
L
E
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------
83
PsiBlast_CBE
46.91
45%
-97
- C4 -
4RNX
1
OYE1_SACPS
B:
[5-83]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
------
P
Q
H
S
-----------
L
T
K
D
E
I
-
K
Q
Y
I
-
K
E
Y
V
Q
A
A
K
N
S
I
-
A
A
G
A
D
G
V
E
I
H
S
A
N
G
Y
L
L
N
Q
F
L
D
P
H
S
N
T
R
T
D
--
E
Y
G
G
S
I
E
N
R
A
R
F
T
L
E
V
V
D
A
L
V
E
A
----------------------------------------------------------------------------------------------------------------------------------------------------
84
PsiBlast_CBE
46.57
45%
-95
- C4 -
4RNX
2
OYE1_SACPS
A:
[5-83]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
------
P
Q
H
S
-----------
L
T
K
D
E
I
-
K
Q
Y
I
-
K
E
Y
V
Q
A
A
K
N
S
I
-
A
A
G
A
D
G
V
E
I
H
S
A
N
G
Y
L
L
N
Q
F
L
D
P
H
S
N
T
R
T
D
--
E
Y
G
G
S
I
E
N
R
A
R
F
T
L
E
V
V
D
A
L
V
E
A
----------------------------------------------------------------------------------------------------------------------------------------------------