@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4735: (2016-03-01 )
MPKGLKRAVSALLITFLVYCLLGFLLIPGIGLRVANQQLAQYATVPARLERIEFNPFSLELTLWGLRLGEEKNPQLAFRRLYANLQLDSLWKRQLHLADVELEGPHTELLFGEKGQLNLASLFRIPPSESPEPEQPSDPFPLRIDRIQLAEGSLHFQDLRPSEPVDFSFDPLGFELHNLSTLPDDGAKMTLVATGPNGGRLDWEGDLTLVPITSRGHLSVKDIQLKAWWPYVRDNAPLVLENGVVSLSSDYRLDLSKDTQLLLDKAALKLADFSINSPQGKPLAKLASLDVAATTLDLAKQEVVLGEVRSQGLEAWAAREKDGQLDWQKLFADFTPPPRKAPAPKPAENTDPAAAPTDAAKTTSEPATDGAAKAAAIASGEASKDRPAEKDASVAETERATDDKESAKAAEGAADKVAKQETSKAPKTGKATGQETAKTAEIDKAASDSPQQLADTAKTPPPESTKASAETPAKPWNIVLRDAQLRGYKAHLVDRQPATEVPLEVGPLDLDLQNVDSLGKTPFDLKLKTGLGNRGQVQASGQVVLDPVSARLKVSTRDIDLRVAQAYISPFIRLELRSGFLGSELAVDLKSVEPLAFSVDGSAEVSQLHTLDTIKDRDFVKWTKLTLNGLAYRHEDSLSIQSVSFEEPYARFIINEDRSTNVSELIIPQPASSSGKTAAESKNAPASKPLGIHIGGVRINNGSANFADLTLMPPFGTAIQQLSGEVGTLDTRNSQPAKVDIKGKVDKYAPVTIAGELDPFDPLKKLDITTSFKRVELTTLTPYSGKFAGYRIRKGRLNLDLHYQIERSQLKAENKVLLEGLQLGEKVDSPDAVDLPVKLAVALLKDTKGNIDIQLPVAGDLNNPEFSVMPIVWQTLRNLVLRAVQAPFKFIAGLAAGGNEDLGTVPFAAGSDELTPEAQANLDKLADALKERPALRLEVEGVASAAADGPSIGAKRLELEYQNTYYRMLQRRGDKVPSDAKQLEVPENMQAPLLEGIYRTRLKQQPPAEWKELDSDERTAKMREAVIASWAKSQVLLRQIGQARATRIKDYLVEKGQLPDDRIYLIDVSFAEGEDKGNVDTQLHLDSE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810......---------.820.......830.....--..840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
P
K
G
L
K
R
A
V
S
A
L
L
I
T
F
L
V
Y
C
L
L
G
F
L
L
IPGI
G
L
R
V
A
N
Q
Q
L
A
Q
YATV
P
A
R
L
E
R
I
EFNP
F
S
L
E
L
T
L
W
G
L
RLGEEK
N
P
Q
L
A
F
R
R
L
Y
A
NL
Q
L
D
S
L
W
K
RQL
H
L
A
D
V
E
LEGPHT
E
L
L
FGEKGQL
N
L
A
S
LFRIPPSESPEPEQPSDPF
P
L
R
I
D
R
I
Q
LAEG
S
L
H
F
QDLRPSEPVDFSFDPL
G
F
E
LHNLSTLPDDG
A
K
M
T
L
V
A
TGPNGG
R
L
DWEG
D
L
T
L
V
P
ITSRG
H
L
S
V
K
D
I
Q
L
K
A
W
WPYVRDNA
P
L
V
L
EN
G
V
V
SLSS
D
Y
R
LDLSK
D
T
Q
L
L
L
D
K
A
A
L
K
L
A
D
F
SINSPQGK
P
L
A
K
L
ASLD
V
A
A
T
T
L
D
L
A
K
Q
E
V
V
L
G
E
V
R
S
Q
G
L
E
A
W
AAREKDGQ
L
D
W
Q
K
L
F
A
DFTPPPRKAPAPKPAENTDPAAAPTDAAKTTSEPATDGAA
K
A
A
A
IASGEASKDRPAEKDASVAETERATDD
K
E
S
A
KAAEG
A
A
D
K
V
A
K
Q
E
TSKAPKTGKATGQETAKTAEIDKAASD
S
P
Q
Q
L
A
D
TAKTPPPESTKASAETPAKP
W
N
I
V
L
RDAQLRG
Y
K
A
H
LVDRQPATEVPLEVGPLDL
D
L
Q
N
V
D
S
LGKT
P
F
D
L
K
L
KTGLGNR
G
Q
V
Q
AS
G
Q
V
V
L
DPVS
A
R
L
K
V
STRD
I
D
L
R
V
A
Q
A
Y
IS
P
F
I
R
L
E
L
RSGFLGSE
L
A
V
DLKSVE
P
L
A
F
SVDGSA
E
V
S
Q
L
HTLDTIKDRD
F
V
K
W
T
K
L
T
LN
G
L
A
YRHEDSL
S
I
Q
SVSFEEP
Y
A
R
F
I
INEDRSTN
V
S
E
L
IIPQPASSSGKTAAESKNAPASK
P
L
G
I
H
I
G
G
V
R
INNGSANFA
D
L
T
LMPP
F
G
T
A
I
Q
Q
L
SGEVGTLDTRNSQP
A
K
V
D
IKGKVDKYA
P
V
T
I
AGELDPFDPLKKLDITT
S
F
K
R
V
E
L
T
T
LTPYSGKFA
G
Y
R
I
RK
G
R
L
N
L
D
L
H
Y
Q
I
E
R
S
QLKAE
N
K
V
L
L
---------
E
G
L
QLGEKVDSPDAVD
L
P
V
--
K
L
A
V
A
L
L
KDTKG
N
I
D
I
Q
L
PVAGDLNNPE
F
S
V
M
P
I
V
W
Q
T
L
R
N
L
V
L
R
A
V
Q
A
P
F
K
F
I
A
G
LAAGGNEDLGTVPFAAGSDELT
P
E
A
QA
N
L
D
K
L
A
D
A
L
K
ERP
A
L
R
L
E
VEGVASAAADGPSIG
A
K
R
L
E
L
EY
Q
N
T
Y
Y
R
M
L
Q
RRGDKVPSD
A
K
QLEVPENMQ
A
P
L
L
E
G
I
Y
R
T
R
LKQQP
P
A
E
W
K
ELDS
D
E
R
T
A
K
M
R
E
A
V
I
A
S
W
A
K
S
Q
V
L
L
R
Q
I
G
Q
A
R
A
T
R
I
K
D
Y
L
V
EKGQLPDD
R
I
Y
L
I
D
V
S
FAEGEDKGNV
D
T
Q
L
H
LDSE
46
Fugue
80.68
12%
-6
- C2 -
2ZF8
-
?
A:
[1-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
M
G
K
R
Y
V
A
T
P
Q
Q
S
Q
W
E
M
V
V
N
T
P
L
E
C
Q
L
V
H
P
I
P
S
F
G
D
A
V
F
S
S
R
A
N
K
K
I
N
L
D
F
E
L
K
M
R
R
P
M
G
E
T
R
N
V
S
L
I
SMPPPWRPG
E
H
A
D
R
I
T
N
L
K
F
F
K
Q
F
D
G
Y
V
GG
Q
T
A
W
G
I
L
S
E
L
E
K
G
R
Y
P
T
F
S
Y
Q
D
W
Q
S
R
D
Q
R
I
E
V
A
L
S
S
V
L
F
Q
N
K
Y
N
A
F
S
D
C
I
S
N
L
L
K
--
Y
S
F
E
D
I
A
F
T
I
L
H
Y
E
R
Q
G
D
Q
L
T
K
A
S
K
K
R
L
S
Q
I
A
D
Y
I
R
H
N
Q
D
I
D
L
V
L
V
A
T
Y
S
--------
A
S
Q
S
L
S
E
R
R
A
E
S
L
R
D
Y
F
Q
S
L
G
----
L
P
E
D
R
I
Q
V
Q
G
Y
G
R
V
V
I
S
L
G
R
T
Q
-----------------------------------------------------------------------------------------
24
HHSearch
77.97
24%
28
* C5 *
2HQS
2
PAL_ECOLI
H:
[6-88]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
V
Y
F
D
L
D
K
Y
D
I
R
S
D
F
A
Q
M
L
D
A
H
A
N
F
L
R
S
N
P
S
Y
K
V
T
V
E
G
H
A
D
E
R
G
T
P
-------------------------------------------------------------------------------------
E
Y
N
I
S
L
G
E
R
R
A
N
A
V
K
M
Y
L
Q
G
K
-
G
V
S
A
D
Q
I
S
I
V
S
Y
G
K
E
-----------------
6
PsiBlast_PDB
72.31
23%
39
- C5 -
1Y1Q
3
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
72.10
23%
34
- C5 -
1RYZ
-
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
72.07
23%
40
- C5 -
1SJ9
-
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
71.83
23%
34
- C5 -
1Y1R
1
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
71.80
23%
33
- C5 -
4OGK
3
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
71.69
23%
37
- C5 -
4E1V
3
UDP_SALTY
A:
[9-138]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
71.68
23%
44
- C5 -
3DDO
2
UDP_SALTY
A:
[9-145]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
71.29
23%
34
- C5 -
2HRD
4
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
71.20
23%
36
- C5 -
1ZL2
2
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
70.95
23%
36
- C5 -
1Y1S
3
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
70.66
23%
37
- C5 -
2PGA
3
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
70.60
23%
40
- C5 -
1Y1T
1
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
70.49
23%
39
- C5 -
3FWP
3
UDP_SALTY
A:
[9-138]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
70.37
23%
34
- C5 -
2HWU
2
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
70.35
23%
41
- C5 -
2HN9
2
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
70.06
23%
42
- C5 -
2HSW
-
UDP_SALTY
A:
[1009-1135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
69.82
23%
39
- C5 -
3DPS
-
UDP_SALTY
A:
[9-135]
-----------------------------
L
G
L
T
K
N
D
L
Q
G
A
Q
L
A
I
V
P
G
D
P
E
R
V
E
-----------
K
I
A
A
L
M
D
K
P
V
K
L
A
S
H
R
E
F
T
S
W
R
A
E
-
L
D
G
K
A
V
I
V
C
S
T
G
I
G
G
P
S
T
S
I
A
V
E
E
L
A
Q
L
G
I
R
T
F
L
R
I
G
T
T
G
A
I
Q
P
H
I
N
V
G
D
V
L
V
T
T
A
S
V
R
L
D
G
A
S
L
H
F
A
P
M
E
F
P
A
V
A
D
F
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
69.73
26%
37
- C5 -
2AIZ
1
PAL_HAEIN
P:
[27-111]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
Y
N
T
V
Y
F
G
F
D
K
Y
D
I
T
G
E
Y
V
Q
I
L
D
A
H
A
A
Y
L
N
A
T
P
A
A
K
V
L
V
E
G
N
T
D
E
R
G
T
P
-------------------------------------------------------------------------------------
E
Y
N
I
A
L
G
Q
R
R
A
D
A
V
K
G
Y
L
A
G
K
-
G
V
D
A
G
K
L
G
T
V
S
Y
G
E
------------------