@TOME V3
(Feb 2022)

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3D Common Core:

Structural Clustering:

Modeller Result :

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : THIK_ECOLI_: (2019-02-06 )
MPFRSNNPITRDELLSRFFPQYHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGAVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRPLRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ

Atome Classification :

(20 SA) -----------------------......---...10........-----------20-------.--------.--.--------------.....30.......-.40-..---------.----------......50......-..60..-......70-.-.----..---...-------.-------80------.-----.--------------......90....-..----.-------------.-----.-----100.......110.-.-------..-------------...120.---------------.--------.-------------....----.130--------........---------140---------------..-----------------....------...150....---.--..160.......170....---...-------180---.-....-....190.----......200...---------------------.---------------------.---------------------..210.....--------.-----.220----.------------.--------.....230.......240.......250..---.-....260.......270...-----------
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) -----------------------MPFRSN---NPITRDELLSRFF-----------PQ-------Y--------H--P--------------VTTFNSGLSGGSFL-IE--HQ---------G----------QRFVVRQPHDPDAP-QSAFLR-QYRALSQL-P-A----CI---APK-------P-------HL------Y-----L--------------RDWMVVD-YLPG-AV----K-------------T-----Y-----LPDTNELAGLLYYL-H-------QQ-------------PRFGW-R---------------I--------T-------------LLPL----LEL---------YWQQSDPA---------R-----------------RT-----------------VGWL------RMLKRLRKAR---E--PRPLRLSPLHMDVHAGNLV---HSA-------S-----G-LKLI-DWEYAGDG----DIALELAAVWVE---------------------N---------------------T---------------------EQHRQLVNDY--------A-----TRAK----I------------Y--------PAQLWRQVRRWFPWLLMLKAGWFEYRWRQT---G-DQQFIRLADDTWRQLL-IKQ-----------
35 HHSearch 79.2816% -40 - C3 - - 5FUT CHKA_HUMAN A:[8-369] ---------------------------TR---RRAY--LWCKEFL-----------PGAWRGLREDE-------F--H--------------ISVIRGGLSNMLFQ-CS--LP---------DTTATLGDEP-RKVLLRLYG-----GAEAMVL-ESVMFAIL-AER----SL---GPK-------L-------YG------I-----FPQGRL---------EQFIPSR-RLDT-EE----L-------------S-----L-----PDISAEIAEKMATF-H-------GM-------------KMPFN-K---------------EPK------W-------------LFGT----MEK---------YLKEVLRIKFTEESRIKKLHKL-------------LS-----------------YNLP------LELENLRSLL---E--STPSPVVFCHNDCQEGNIL---LLEGRENSEKQ-----K-LMLI-DFEYSSYN----YRGFDIGNHFCE---------------------WMYDYSYEKYPFFRANIRKYPTK---------------------KQQLHFISSY--------L-----PAFQ----NDFENLSTEEKSII--------KEEMLLEVNRFALASHFLWGLWSIVQAKISS--I-EFGYMDYAQARFDAY----------------
34 HHSearch 78.8716% -37 - C3 - - 5FTG CHKA_HUMAN A:[8-369] ---------------------------TR---RRAY--LWCKEFL-----------PGAWRGLREDE-------F--H--------------ISVIRGGLSNMLFQ-CS--LP---------DTTATLGDEP-RKVLLRLYG-------EAMVL-ESVMFAIL-AER----SL---GPK-------L-------YG------I-----FPQGRL---------EQFIPSR-RLDT-EE----L-------------S-----L-----PDISAEIAEKMATF-H-------GM-------------KMPFN-K---------------EPK------W-------------LFGT----MEK---------YLKEVLRIKFTEESRIKKLHKL-------------LS-----------------YNLP------LELENLRSLL---E--STPSPVVFCHNDCQEGNIL---LLEGRENSEKQ-----K-LMLI-DFEYSSYN----YRGFDIGNHFCE---------------------WMYDYSYEKYPFFRANIRKYPTK---------------------KQQLHFISSY--------L-----PAFQ----NDFENLSTEEKSII--------KEEMLLEVNRFALASHFLWGLWSIVQAKISS--I-EFGYMDYAQARFDAY----------------
29 HHSearch 77.2117% -23 - C3 - - 3C5I ? D:[14-352] ----------------------------P---LYIK--KICLEKV-----------PE-------WNHFTEDN-L--R--------------VKQIL--LTNQLFE-VG--LK---------EETANNYNSIRTRVLFRIYGKHVDE-LYNTIS-EFEVYKTM-SKY----KI---APQ-------L-------LN------T-----FNGGRI---------EEWLYGD-PLRI-DD----L-------------K-----N-----PTILIGIANVLGKF-H-------TL-------------SRKRH-LPEH------------WDRTP----C-------------IFKM----MEK---------WKNQLFKY---------KNIEKYNC----------DIHKYI-------------KESD------KFIKFMKVYSKS-D--NLANTIVFCHNDLQENNII---NTN-------K-----C-LRLI-DFEYSGFN----FLATDIANFFIE---------------------TSIDYSVSSYPFFEIDKKKYISY---------------------ENRKLFITAY--------L-----SNYLDKVVP------------TPKL-----IDEILEAVEVQALGAHLLWGFWSIIRGYQTKSYN-EFDFFLYAEQRLKMY----------------
24 HHSearch 75.3718% -42 - C3 - - 1NW1 - CKA2_CAEEL A:[58-415] --------------------------------------MLCARFL-----------GG-------AWKTVPLEHL--R--------------ISRIKGGMSNMLFL-CR--LSEVYPPIRNEP----------NKVLLRVYFNPE-T-ESHLVA-ESVIFTLL-SER----HL---GPK-------L-------YG------I-----FSGGRL---------EEYIPSR-PLSC-HE----I-------------S-----L-----AHMSTKIAKRVAKV-H-------QL-------------EVPIW-KEP-------------D--------Y-------------LCEA----LQR---------WLKQLTGT---------VDAEHRFDLPEECGVSSVNC-----------------LDLA------RELEFLRAHI---S--LSKSPVTFCHNDLQEGNIL---LPK-------------R-LVLI-DFEYASYN----YRAFDFANHFIE---------------------W---------------------TIDYDIDEAPFYKIQTENFPENDQMLEFFLNY--------L-----REQG----N------------TRENELYKKSEDLVQETLPFVPVSHFFWGVWGLLQVELSP--V-GFGFADYGRDRLSLY----------------
25 HHSearch 74.4518% -40 - C3 - - 1NW1 - CKA2_CAEEL B:[58-415] --------------------------------------MLCARFL-----------GG-------AWKTVPLEHL--R--------------ISRIKGGMSNMLFL-CR--LSEVYPPIRNEP----------NKVLLRVYFNPE-T-ESHLVA-ESVIFTLL-SER----HL---GPK-------L-------YG------I-----FSGGRL---------EEYIPSR-PLSC-HE----I-------------S-----L-----AHMSTKIAKRVAKV-H-------QL-------------EVPIW-KEP-------------D--------Y-------------LCEA----LQR---------WLKQLTGT---------VDAEHRFDLPEECGVSSVNC-----------------LDLA------RELEFLRAHI---S--LSKSPVTFCHNDLQEGNIL---LPK-------------R-LVLI-DFEYASYN----YRAFDFANHFIE---------------------W---------------------TIDYDIDEAPFYKIQTENFPENDQMLEFFLNY--------L-----REQG----N------------TRENELYKKSEDLVQETLPFVPVSHFFWGVWGLLQVELSP--V-GFGFADYGRDRLSLY----------------
42 HHSearch 70.7317% 6 - C3 - - 5IWU ? A:[1-299] ------------------------MSKDI---KQVI--EIAKKHN-----------LF-------LKE------E--T--------------IQFNESGLDFQAVF-AQ--DNN--------G----------IDWVLRLPRRED-V-MPRTKV-EKQALDLV-NKY----AISFQAPN-------W-------II------YTEELIA--------------YKKLDGV-PAGT-ID----HNIGNYIWEIDINNV-----P-----ELFHKSLGRVLAEL-H-------SI-------------PSNKA-AA--------------LDLVVH---T-------------PEEA----RMS---------MKQRMDAV---------RA----------------KF-----------------GVGE------NLWNRWQAWLNDDD--MWPKKTGLIHGDVHAGHTM---IDKD------A-----NVTGLI-DWTEAKVT----DVSHDFIFNYRA---------------------FG--------------------E---------------------EGLEALILAY--------K-----EIGG----Y------------Y--------WPKMKEHIIELNAAY---PVSIAEFA-LVS---G-IEEYEQMAKEALEV-----------------
43 HHSearch 70.1117% 7 - C3 - - 5UXA - ? A:[2-299] -------------------------SKDI---KQVI--EIAKKHN-----------LF-------LKE------E--T--------------IQFNESGLDFQAVF-AQ--DNN--------G----------IDWVLRLPRRED-V-MPRTKV-EKQALDLV-NKY----AISFQAPN-------W-------II------YTEELIA--------------YKKLDGV-PAGT-ID----HNIGNYIWEIDINNV-----P-----ELFHKSLGRVLAEL-H-------SI-------------PSNKA-AA--------------LDLVVH---T-------------PEEA----RMS---------MKQRMDAV---------RA----------------KF-----------------GVGE------NLWNRWQAWLNDDD--MWPKKTGLIHGDVHAGHTM---IDKD------A-----NVTGLI-DWTEAKVT----DVSHDFIFNYRA---------------------FG--------------------E---------------------EGLEALILAY--------K-----EIGG----Y------------Y--------WPKMKEHIIELNAAY---PVSIAEFA-LVS---G-IEEYEQMAKEALEV-----------------
48 SP3 70.0417% -19 - C3 - - 1NW1 - CKA2_CAEEL A:[32-426] ---------------GMKELLSTMDLDTDANTIPELKERAHMLCARFLGGAWKTVPLE-------H--------L--R--------------ISRIKGGMSNMLFL-CR--LS---------EVYPPIRNEP-NKVLLRVYF-NPET-ESHLVA-ESVIFTLLSE-R----HL---GPK-------L-------YG------I-----F--------------SGGRLEE-YIPS-RP----L-------------SCHEISL-----AHMSTKIAKRVAKV-H-------QL-------------EVPIW-KEP-------------D--------Y-------------LCEA----LQR---------WLKQLTGT---------V-----------------DAEHRFDLPEECGVSSVNCLDLA------RELEFLRAHI---S--LSKSPVTFCHNDLQEGNIL---LP--------K-----R-LVLI-DFEYASYN----YRAFDFANHFIEWTIDYDIDEAPFYKIQTENFPE---------------------N---------------------DQMLEFFLNY--------L-----REQG----N------------TRENELYKKSEDLVQETLPFVPVSHFFWGVWGLLQVELS---PVGFGFADYGRDRLSLYFKHKQLLKNLA-----
40 HHSearch 69.4917% -16 - C3 - - 5IGI ? A:[7-299] --------------------------ADT---SQLY--ALAARHG-----------LK-------LH-------G--P--------------LTVNELGLDYRIVI-AT--VDD--------G----------RRWVLRIPRRAE-V-SAKVEP-EARVLAML-KNRL---PFA--VPD-------W-------RV------A-----NAELVAYPMLEDSTA-VIQPGS-STPD-WVVP--Q-------------D-----S-----EVFAESFATALAAL-H-------AV-------------PISAA-V---------------DA-------GMLIRTPTQ-----ARQK----VAD---------DVDRVRRE---------FVV---------------ND-----------------KRLH------RWQRWLDDDS------SWPDFSVVVHGDLYVGHVL---IDNTE-----R-----V-SGMI-DWSEARVD----DPAIDMAAHLMV---------------------F---------------------GE--------------------EGLAKLLLTY--------E-----AAGG----R------------V--------WPRLAHHIAERLAFGAVTYALF----ALDS---G-NEEYLAAAKAQLAA-----------------
60 Fugue 68.9211% -7 - C3 - - 2QG7 - ? A:[50-458] YPITESNLRILEGEDRSEKAKELLKKYVS---NVFENEKTLYIYC-----------KY-------V--------M--LHYGKDLVNPNEVDSLEFQIINGTNILIK-VKDMSK---------Q----------AKYLIRLYGPTDEI-INRERE-KKISCILY-N-K----NI---AKK-------I-------YV------F-----F--------------TNGRIEE-FMDG-YA----L-------------S-----REDIKNPKFQKLIAKNLKLL-HDIKLNENLY-------------KELQV-T---------------QKVPGTRPSF-------------LWNT----IWK---------YFHLLNEE---------R-----------------KKICSFDAKANILKLIDF-DVLR------DSIVEVESLC---K--RENSPIVLCHCDLLSSNIINTVGEG-------D-----S-ISFI-DFEYSCPM----ERAYDIANHFNE---------------------YAGFNCDWDLTPS---------K---------------------EEEYHFIMHY--------L-----GTDD----E------------E--------LINQLIREIQPFYICSHINWGLWSLLQGMH-----SFDFINYGMTRLTASC-LPIFRSKV------
69 Fugue 68.6713% -11 - C3 - - 2PPQ - KHSE_AGRFC A:[5-320] --------------------------------TDIT-EDELRNFL-----------TQ-------Y--------DVGS--------------LTSYKGIAENSNFL-LH--TT---------K----------DPLILTLYEKKNDL-PFFLGLMQHLAAKGL-S-C----PL---PLPRKDGELLG-------EL------S-----G--------------RPAALIS-FLEGMWL----R-------------K-----P-----EAKHCREVGKALAAMH-------LAS------------EGFEI-K---------------R--------P-------------NALS----VDG---------WKVLWDKS---------E-----------------ER-----------------ADEVEKGLREEIRPEIDYLA---AHWPKDLPAGVIHADLFQDNVF---FLG-------D-----E-LSGLIDFYFACND----LLAYDVSICLNAWCFEKDGAY------------N---------------------V---------------------TKGKALLEGY--------QSVRPLSEAE----L------------E--------ALPLLSRGSALRFFLTRLYDWLTTPAGALV---V-KKDPLEYLRKLRFHRT-IANVAEYGLA----
30 HHSearch 68.5316% 8 - C3 - - 3DXQ - ? B:[2-281] ---------------------------MT---DEAR--AKLAAIP-----------ML-------AGY------T--G--------------PLERLGGLTNLVFR-A-------------------------GDLCLRIP---------NRAN-EAVAAREA-AKA----GV---SPE-------V-------LH------V-----DPATGVMV-------TRYIAGAQTMSP-EK----F-------------KT----R-----PGSPARAGEAFRKL-H-------GS-------------GAVFPFR---------------F--------E-------------LFAM----IDD---------YLKVLSTK---------NVTLPA------------GY-----------------HDVV------REAGGVRSAL---A--AHPLPLAACHCDPLCENFL---DTG-------E-----R-MWIV-DWEYSGMN----DPLWDLGDLSVE---------------------GKFN------------------A---------------------NQDEELMRAY--------F-----GGEA--------------------------RPAERGRVVIYKAMCDLLWTLWGLIQLAND---NPVDDFRAYADGRFARC----------------
39 HHSearch 68.5117% -11 - C3 - - 5IGH - ? A:[7-299] --------------------------ADT---SQLY--ALAARHG-----------LK-------LH-------G--P--------------LTVNELGLDYRIVI-AT--VDD--------G----------RRWVLRIPRRAE-V-SAKVEP-EARVLAML-KNRL---PFA--VPD-------W-------RV------A-----NAELVAYPMLEDSTAMVIQPGS-STPD-WVVP--Q-------------D-----S-----EVFAESFATALAAL-H-------AV-------------PISAA-V---------------DA-------GMLIRTPTQ-----ARQK----VAD---------DVDRVRRE---------FVV---------------ND-----------------KRLH------RWQRWLDDDS------SWPDFSVVVHGDLYVGHVL---IDNTE-----R-----V-SGMI-DWSEARVD----DPAIDMAAHLMV---------------------F---------------------GE--------------------EGLAKLLLTY--------E-----AAGG----R------------V--------WPRLAHHIAERLAFGAVTYALF----ALDS---G-NEEYLAAAKAQLAA-----------------
65 Fugue 67.4216% 5 - C3 - - 1ZYL - SRKA_ECOLI A:[4-328] ---------------------SAFTFQTL---HPDTIMDALFEHG-----------IR-------V--------D--S--------------GLTPLNSYENRVYQ-FQD-ED---------R----------RRFVVKFYRPERWT-ADQILE-EHQFALQL-V-NDEVPVA---APV-------AFNGQTLLNH------Q-----G--------------FYFAVFP-SVGG-RQFE--A-------------D-----N-----IDQMEAVGRYLGRM-H-------QTGRKQLFIHRPTIGLNEYL-I---------------E--------P-------------RKLF----EDA---------TLIPSGLK---------A-----------------AF-----------------LKAT------DELIAAVTAH---W--REDFTVLRLHGDCHAGNIL---WR--------D-----G-PMFV-DLDDARNGPAVQDLWMLLNGDKAE---------------------Q---------------------R---------------------MQLETIIEAYEEFSEFDTA-----EIGL----I------------E--------PLRAMRLVYYLAWLMRRWADPAFPKNFPWL---T-GEDYWLRQTATFIEQA-KVLQEPPLQLTPMY
32 HHSearch 67.2414% -7 - C3 - - 3CSV ? A:[4-302] --------------------------SRE---DEIR--DFLATHG-----------YA-------D--------W--N--------------RTP--------RYQRLR--SP---------TG---------AKAVLMDWSPEE---GGDTQP-FVDLAQYL-RNL----DIS--APE-------I-------YA------E-----EHARGLLL-------IEDLGDA-LFTE-VINNDPA-------------Q-----E-----MPLYRAAVDLLIHL-H-------DA-------------QTPEL-AR--------------L--------DPET----------LSEMTRLAFSE---------YRYAILGD---------A-----------------AE-----------------DNRK------RFEHRFAQIL---SA-QLEGDMVFVHRDFHAQNLL---WLP-------EREGLAR-VGVI-DFQDAKLG----HRAYDLVSLLQD---------------------A---------------------RRDVPA----------------QVEAQMIDHY--------I-----QATG----V------------D--------ESHFRSAYAVIAVQRNMRILGIFARLSQRF---G-KRHYIEFVPRVWAHFE-R-------------
23 HHSearch 66.2315% 7 - C3 - - 2QG7 - ? E:[112-450] -----------------------------------------------------------------------------E--------------FQIING-ITNILIK-VK--DMSK-------Q----------AKYLIRLYGPKTDE-IINRER-EKKISCIL-YNK----NI---AKK-------I-------YV------F-----FTNGRI---------EEFMDGY-ALSR-ED----I-------------K-----N-----PKFQKLIAKNLKLL-H-------DI-------------KLNEN-LYKELQVTQKVPGTRPS--------F-------------LWNT----IWK---------YFHLLNEE---------RKKICSFDAKANILKLI-DF-----------------DVLR------DSIVEVESLC---K--RENSPIVLCHCDLLSSNII---NTVGG-----D-----S-ISFI-DFEYSCPM----ERAYDIANHFNE---------------------YAGFNCDWDLTPS---------K---------------------EEEYHFIMHY--------L-----GTDD----EE-----------L--------INQLIREIQPFYICSHINWGLWSLLQGMHS---S-DFDFINYGMTRLTASC---------------
26 HHSearch 65.5115% 17 - C3 - - 4R78 ? A:[21-281] ---------------------------ME---KIIK--EKISSLL-----------SQ-------EEEV-----L--S--------------VEQL-GGMTNQNYL-AK--TT---------N----------KQYIVKFFGKGTEK-LINRQD-EKYNLELL-KDL----GLD--VKN-------Y-------LFDIEAGIK-----V--------------NEYIESAITLDS-TS------------------------I-----KTKFDKIAPILQTI-H-------TS-------------AKELR-GE--------------F--------A-------------PFEE----IKK---------YESLIEEQ---------IPYA--------------NY-----------------ESVR------NAVFSLEKRL---A--DLGVDRKSCHIDLVPENFI---ESPQ------G-----R-LYLI-DWEYSSMN----DPMWDLAALFLE---------------------SEFT------------------S---------------------QEEETFLSHY--------E-----SDQ---------------------------TPVSHEKIAIYKILQDTIWSLWTVYKEEQ-------------------------------------
22 HHSearch 65.1615% 10 - C3 - - 2QG7 - ? D:[112-450] -----------------------------------------------------------------------------E--------------FQIINGG-TNILIK-VK--DMSK-------Q----------AKYLIRLYGPKTD----NRER-EKKISCIL-YNK----NI---AKK-------I-------YV------F-----FTNGRI---------EEFMDGY-ALSR-ED----I-------------K-----N-----PKFQKLIAKNLKLL-H-------DI-------------KLNEN-LYKELQVTQKVPGTRPS--------F-------------LWNT----IWK---------YFHLLNEE---------RKKICSFDAKANILKLI-DF-----------------DVLR------DSIVEVESLC---K--RENSPIVLCHCDLLSSNII---NTVG------D-----S-ISFI-DFEYSCPM----ERAYDIANHFNE---------------------YAGFNCDWDLTPS---------K---------------------EEEYHFIMHY--------L-----GTDD----EE-----------L--------INQLIREIQPFYICSHINWGLWSLLQGMHS---S-DFDFINYGMTRLTASC---------------
27 HHSearch 63.8715% 19 - C3 - - 4R7B - ? A:[21-281] ---------------------------ME---KIIK--EKISSLL-----------SQ-------EEEV-----L--S--------------VEQL-GGMTNQNYL-AK--TT---------N----------KQYIVKFFGKGTEK-LINRQD-EKYNLELL-KDL----GLD--VKN-------Y-------LFDIEAGIK-----V--------------NEYIESAITLDS-TS------------------------I-----KTKFDKIAPILQTI-H-------TS-------------AKELR-GE--------------F--------A-------------PFEE----IKK---------YESLIEEQ---------IPYA--------------NY-----------------ESVR------NAVFSLEKRL---A--DLGVDRKSCHIDLVPENFI---ESPQ------G-----R-LYLI-DWEYSSMN----DPMWDLAALFLE---------------------SEFT------------------S---------------------QEEETFLSHY--------E-----SDQ---------------------------TPVSHEKIAIYKILQDTIWSLWTVYKEEQ-------------------------------------
45 HHSearch 63.1415% -16 - C3 - - 3F7W ? A:[3-287] --------------------------------NSVA--ARVTELT-----------GR-------EV-------A--A--------------VAERGHSHRWHLYR-VE--LAD--------G----------TPLFVKALPDDAPALDGLFRA-EALGLDWL-GRSF---GSP--VPQ-------V-------AG------W-----D--------------DRTLAME-WVDE-RP----P-------------------T-----PEAAERFGHQLAAM-H-------LA-------------GAESF-G---------------A--------TWDGYIGPLPMDNTPRST----WPEFYAEQRILPYLRRAADR---------GA----------------LT-----------------PGDV------RLVEKVLDALDHLA--GDPEPPARIHGDLWNGNVL---WQD-------D-----G-AVVI-DPA-AHGG----HREADLAMLALF---------------------G---------------------L---------------------PYLDRVRDAY--------N-----EVAP-----------------L--------AEGWRARIPLHQLHPLLVHVCLFG------------AAYRTTLVDTARAAL-R-------------