@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : E8PLS8_THESS: (2019-01-28 )
MGLRKTYAKPYSRGISSPLEALRISPVVLSALKGLLSPDTLSRLTPLGGFEARVYTDGERVYKVYQPGEAHLAALEAERMARAGLGSFVLGVAQVEGQGILVIRHFPGKPFSPESFTPKALAALSHLFLSLHRLPEPGYVEREELSERLERFAESLGSVPEALSLIKALMREVTWVAGVEKRFCHRDAWAGNLLLKTQENPSHDDPEVLLVDWVRSGGDDPARDLALLKTGSLDLLGEKRAREALFRLVQFYPKEVRERLAFYVPLTYLHDLHWFRTKKPEGFLEALADKLPRALSFFQDCFPLRNRAC
Atome Classification :
(20 SA)
------------------.........10........20.....--...30.-...--.-------..-.------40......-..------50-----..--....----.-------.-------------.60.---..----...----------..----70-....-----------....---.80--..-..---.---.---...90-------.---.------------..-...-.-.100.......-110--.-.....-------..----.--120.....-----..130.----.-.---....-140---------------------------.-.----.----.---------.....150.--------...---------------..-------------.160----------------.---.---.---------.---..-------------...170.-.-----------.-----....------180------.-----......190......------.-200...-------...--------------.210------...---...-----...----------220--......-------.-.----------------.230-----------..-....-----------..------------.240--.---....-....250-------..--------.-----.-----------------....260.-...-...270..----.----.-----.....---280----.-----........----------290.......300.-......------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------MGL
R
K
T
Y
A
K
P
Y
SRGISS
P
L
E
A
LRI
S
P
--
V
V
L
S
A
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-
K
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L--L-------S
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T
L
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RLTPL-GG------
F
------
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--
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T----D-------G-------------
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---
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----YQP----------GE----
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---
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L
---
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F
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N
L
L
L
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TQ------E-NPSHDD-------P
E
V
--------------
L
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--------
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---
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----
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A
L
A
D
----------
K
L
P
R
A
L
S
F
F
Q
D
C
F
P
-LRNRAC------
49
HHSearch
83.83
23%
-25
- C7 -
-
3DXQ
-
?
B:
[19-288]
-----------------------------------------------------------------------------
Y
T
G
P
L
E
R
L
G
G
------
L
------
T
N
--
L
V
F
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----
A
-------
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-------------
D
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---
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--------------
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---
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--------
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P
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-----------------
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----------
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P
---------------
50
HHSearch
80.28
23%
-20
- C- -
-
3DXQ
-
?
A:
[19-288]
-----------------------------------------------------------------------------
Y
T
G
P
L
E
R
L
G
G
------
L
------
T
N
--
L
V
F
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----
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-------
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-------------
D
L
C
L
---
R
I
----
P
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-----------------Y-
I
N
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A
-----------
N
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A
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---
A
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---
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---
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---------
A
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-----------
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---
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P
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N
F
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D
T
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----------------------
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--------------
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--------
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A
--------
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--------
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P
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-----------------
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G
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-
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A
M
-
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D
L
L
--
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----
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F
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A
Y
A
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----------
R
F
A
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C
K
A
L
M
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T
P
---------------
51
HHSearch
79.56
18%
-28
- C7 -
-
1NW1
-
CKA2_CAEEL
A:
[52-420]
-----------------------------------------
L
K
E
--
R
A
H
M
L
C
-
A
R
F
--
L
-------
G
G
-
A
WKTVPL
E
H
L
R
I
S
R
I
K
G
G
------
M
------
S
N
--
M
L
F
L
----
C
R
L
-----
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EVYPPIRNEPN--
K
V
L
L
---
R
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----
Y
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N
----------
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----
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-
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P
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--------
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---
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------------
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-------
G
G
R
L
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Y
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A
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-----------------------------
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----
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----
Y
---------
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C
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L
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--------
K
Q
L
---------------
T
G
-------------
T
V
DAE
H
R
F
D
-----------
L
---
P
---
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ECGVSSVN
C
L
---
D
L
-------------
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F
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-----------
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I
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---
L
S
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------
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-----
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-----------------------
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L
--------------
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A
-----
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Y
N
----------
Y
----
R
A
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D
F
A
-------
N
-
H
----------------
F
I
-------------
E
W
T
I
D
Y
D
IDEAPF
Y
K
I
Q
T
E
N
------------
F
P
----
E
---
N
D
Q
M
-
L
E
F
F
L
N
--------
Y
L
--------
R
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Q
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N
TRENE
L
Y
K
K
S
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D
-----
L
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Q
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T
L
P
F
-
V
P
V
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--
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L
L
Q
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---
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G
F----
G
F
A
D
Y
G
R
D
----------
R
L
S
L
Y
F
K
H
K
Q
-----------------
52
HHSearch
78.34
18%
-28
- C7 -
-
1NW1
-
CKA2_CAEEL
B:
[52-420]
-----------------------------------------
L
K
E
--
R
A
H
M
L
C
-
A
R
F
--
L
-------
G
G
-
A
WKTVPL
E
H
L
R
I
S
R
I
K
G
G
------
M
------
S
N
--
M
L
F
L
----
C
R
L
-----
S
EVYPPIRNEPN--
K
V
L
L
---
R
V
----
Y
F
N
----------
P
E
----
T
E
-
S
H
L
V
-----------
A
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S
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---
I
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----
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A
----
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--
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A
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V
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Q
----
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-
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---
V
P
I
W
-
K
-----------------------------
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----
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----
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C
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F
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-----------
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L
Y
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Y
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K
H
K
Q
-----------------
43
Fugue
75.64
18%
21
- C7 -
-
4OCV
2
?
A:
[24-378]
-----T
N
E
A
L
F
D
V
A
S
H
FA
L
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T
V
D
S
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---
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---------------------
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N
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A
T
------
T
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K
A
R
A
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IDLDTIM
P
G
S
--------------
M
L
--------
F
D
F
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D
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I
R
F
-----
G
A
S
TAL-------
E
----
D
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D
L
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----------------
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A
-------------
Y
T
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A
---
R
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L
L
P
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--------
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Y
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-----
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N
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----------
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L
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E
Q
R
A
D
E
-
T
R
A
I
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A
D
V
M
E
T
T
58
HHSearch
74.13
14%
-22
- C7 -
-
5FTG
11
CHKA_HUMAN
A:
[9-374]
------------------------------------------
R
R
--
R
A
Y
L
W
C
-
K
E
F
--
L
-------
P
G
A
W
RGLRE-
D
E
F
H
I
S
V
I
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G
------
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L
F
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K
V
L
L
---
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L
----
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--------------------
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-----------
L
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---
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A
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---
L
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L
Y
--------
G
---
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------------
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------
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R
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E
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R
-
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----
L
-
D
T
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L
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----
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A
E
K
-----
M
A
T
F
H
G
----
M
-
K
---
M
P
F
N
-
K
-----------------------------
E
-
P
----
K
----
W
---------
L
F
G
T
M
E
K
Y
L
--------
K
E
V
---------------
L
R
-------------
I
K
FTE
E
S
R
I
-----------
K
K
L
-
H
K
L
L
S
---------
Y
---
N
L
-------------
P
L
E
L
E
N
L
R
S
-----------
L
L
E
---
S
T
P
S
------
P
V
V
------
F
-----
C
H
N
D
C
Q
E
G
N
I
L
L
L
E
G
------
R
-
E
-
N
S
E
K
-------
Q
K
L
--------------
M
L
--------
I
D
F
---
E
Y
S
-----
S
Y
N
----------
Y
----
R
G
F
D
I
G
-------
N
-
H
----------------
F
C
-------------
E
W
M
Y
D
Y
S
YEKYPF
F
R
A
N
I
R
K
------------
Y
P
----
T
---
K
K
Q
Q
-
L
H
F
I
S
S
--------
Y
L
--------
P
A
F
---
Q
NDFENLS
T
E
E
K
S
I
I
K
E
E
M
L
L
E
V
N
R
F
-
A
L
A
-
S
H
F
L
--
W
G
----
L
----
W
-----
S
I
V
Q
A
---
K
ISSI--
E
F----
G
Y
M
D
Y
A
Q
A
----------
R
F
D
A
Y
F
H
Q
K
R
-----------------
72
SP3
73.18
17%
-33
- C7 -
-
1NW1
-
CKA2_CAEEL
A:
[32-426]
-------------------
G
M
K
E
L
L
S
T
--
M
D
L
D
T
D
A
N
T
I
P
E
L
K
E
--
R
A
H
M
L
C
-
A
R
F
--
L
GGAWKTV
P
L
-
E
------
H
L
R
I
S
R
I
K
-
G
G
------
M
------
S
N
--
M
L
F
L
----
C
-------
R
L
S
EVYPPIRNEPN
K
V
L
L
---
R
V
----
Y
F
N
----------
P
E
T
E
S
H
L
--
V
A
E
S
-----------
V
I
F
T
---
L
L
---
S
E
-
R
H
---
L
---
G
---
P
K
L
Y
--------
G
---
I
------------
F
S
-------
G
G
R
L
E
E
Y
I
P
S
R
-
P
----
L
-
S
C
H
E
I
S
------
L
A
----
H
--
M
S
T
K
I
A
K
R
-----
V
A
K
V
H
Q
----
L
-
E
---
V
P
I
W
-
K
-----------------------------
E
-
P
----
D
----
Y
---------
L
C
E
A
L
Q
R
W
L
--------
K
Q
L
---------------
T
G
T
V
DAE
H
R
F
D
L
PEE
C
G
------------------
V
---
S
---
S
---------
V
---
N
C
-------------
L
D
L
A
R
E
L
-
E
-----------
F
-----
L
R
A
H
------
I
S
L
SKSPVT
F
-----
C
H
N
D
L
Q
E
G
N
I
L
L
P
K
R
L
V
L
I
DF
E
-
Y
A
S
Y
N
Y
-------
R
A
F
--------------
D
F
A
N
H
F
I
E
W
T
I
D
Y
---
D
I
D
-----
E
A
P
F
Y
K
I
Q
TENFP
E
----
N
D
Q
M
L
E
-------
F
-
F
----------------
L
N
--------------
Y
-
L
R
E
Q
-----------
G
N
------------
T
R
--------
E
N
E
L
-
Y
K
K
S
E
D
--------
L
V
--------
Q
-----
E
-----------------
T
L
P
----
F
-
V
P
V
-
S
H
F
F
--
W
G
----
V
----
W
-----
G
L
L
Q
V
---
E
------
L
SPVGF
G
F
A
D
Y
G
R
D
----------
R
L
S
L
Y
F
K
H
K
Q
L
L
K
N
-
L
A
----------
47
HHSearch
72.23
18%
4
- C7 -
-
4R78
2
?
A:
[38-304]
----------------------------------------------------------------------------
E
V
L
S
V
E
Q
L
-
G
G
------
M
------
T
N
--
Q
N
Y
L
----
A
K
T
TN---
K
-------------
Q
Y
I
V
---
K
F
----
F
G
K
----------
G
T
----
E
KL
I
N
R
Q
-----------
D
E
K
Y
---
N
L
E
L
L
K
D
-
L
G
---
L
---
D
V--
K
N
Y
L
--------
F
---
D
-------------
I
-
E
---
A
-
G
I
K
V
N
E
Y
I
E
S
A
I
T
----
L
-
D
S
T
S
--------
I
K
----
T
--
K
F
D
K
I
A
P
I
-----
L
Q
T
I
H
T
----
S
-
A
---
K
E
L
R
-
G
-------------------------------
E
----
F
----
A
---------
P
F
E
E
I
K
K
Y
E
--------
S
L
I
---------------
E
E
-------------
Q
I
------------------
P
YA-
N
---
Y
---------
E
---
S
V
-------------
R
N
A
V
F
S
L
E
K
-----------
R
L
A
---
D
L
G
V
------
D
R
K
------
S
-----
C
H
I
D
L
V
P
E
N
F
I
E
S
P
Q
---------
G
------------
R
L
--------------
Y
L
--------
I
D
W
---
E
Y
S
-----
S
M
N
----------
D
----
P
M
W
D
L
A
-------
A
-
L
----------------
F
L
-------------
E
S
E
F
T
S
Q
-----------
E
E
---------------------------
E
T
F
L
S
H
--------
Y
E
--------
S
DQ
T
P
-
V
-----------------
S
H
E
K
I
A
I
Y
-
K
I
L
-
Q
D
T
I
--
W
S
----
L
----
W
-----
T
V
Y
K
E
---
E
Q
-----
G
E----
D
F
G
D
Y
G
V
N
----------
R
Y
Q
R
A
V
K
G
L
A
S
Y
G
--------------
48
HHSearch
71.27
18%
12
- C7 -
-
4R7B
-
?
A:
[38-304]
----------------------------------------------------------------------------
E
V
L
S
V
E
Q
L
-
G
G
------
M
------
T
N
--
Q
N
Y
L
----
A
K
T
TN---
K
-------------
Q
Y
I
V
---
K
F
----
F
G
K
----------
G
T
----
E
KL
I
N
R
Q
-----------
D
E
K
Y
---
N
L
E
L
L
K
D
-
L
G
---
L
---
D
V--
K
N
Y
L
--------
F
---
D
-------------
I
-
E
---
A
-
G
I
K
V
N
E
Y
I
E
S
A
I
T
----
L
-
D
S
T
S
--------
I
K
----
T
--
K
F
D
K
I
A
P
I
-----
L
Q
T
I
H
T
----
S
-
A
---
K
E
L
R
-
G
-------------------------------
E
----
F
----
A
---------
P
F
E
E
I
K
K
Y
E
--------
S
L
I
---------------
E
E
-------------
Q
I
------------------
P
YA-
N
---
Y
---------
E
---
S
V
-------------
R
N
A
V
F
S
L
E
K
-----------
R
L
A
---
D
L
G
V
------
D
R
K
------
S
-----
C
H
I
D
L
V
P
E
N
F
I
E
S
P
Q
---------
G
------------
R
L
--------------
Y
L
--------
I
D
W
---
E
Y
S
-----
S
M
N
----------
D
----
P
M
W
D
L
A
-------
A
-
L
----------------
F
L
-------------
E
S
E
F
T
S
Q
-----------
E
E
---------------------------
E
T
F
L
S
H
--------
Y
E
--------
S
DQ
T
P
-
V
-----------------
S
H
E
K
I
A
I
Y
-
K
I
L
-
Q
D
T
I
--
W
S
----
L
----
W
-----
T
V
Y
K
E
---
E
Q
-----
G
E----
D
F
G
D
Y
G
V
N
----------
R
Y
Q
R
A
V
K
G
L
A
S
Y
G
--------------
34
Fugue
70.40
11%
-11
- C7 -
-
2QG7
-
?
A:
[50-458]
-YPITESNLRILEGED
R
S
E
K
A
K
E
L
L
K
K
Y
V
S
N
V
F
E
N
E
K
T
L
Y
I
Y
C
K
--
Y
V
M
L
H
Y
G
K
D
L
--
V
-------
N
P
-
N
------
E
V
D
S
L
E
F
Q
-
I
I
NGT
N
I
L
I
------
K
V
--
K
D
M
S
----
K
-------
Q
-------------
A
K
Y
L
---
I
R
----
L
Y
G
----------
P
T
----
D
--
E
I
I
N
-----------
R
E
R
E
---
K
K
---
I
S
-
C
I
---
L
---
Y
---
N
K
N
I
--------
A
---
K
------------
K
I
-
Y
V
F
F
T
-
N
G
R
I
E
E
F
M
D
G
Y
-
A
----
L
-
S
R
E
D
I
K
------
N
P
----
K
--
F
Q
K
L
I
A
K
N
-----
L
K
L
L
H
D
IKLN
E
-
N
---
L
Y
K
E
-
L
-----------------------------
Q
-
V
----
T
----
Q
KVPGTRPSF
L
W
N
T
I
W
K
Y
F
--------
H
L
L
---------------
N
E
-------------
E
R
K
KICSFDAKA
N
I
L
K
L
ID
F
D
---
V
---
L
---------
R
---
D
S
-------------
I
V
E
V
E
S
L
-
C
-----------
K
-----
R
E
N
S
------
P
I
V
------
L
-----
C
H
C
D
L
L
S
S
N
I
I
N
------------
T
V
G
E
G
-------
D
S
I
--------------
S
F
--------
I
D
F
---
E
Y
S
-----
C
P
M
----------
E
----
R
A
Y
D
I
A
-------
N
-
H
----------------
F
N
-------------
E
Y
-
A
G
F
N
-----------
C
D
------------
W
D
----
L
TPS
K
E
E
E
-
Y
H
F
I
M
H
--------
Y
L
GTDD
E
E
L
I
N
-----
Q
-----------------
L
I
R
E
I
Q
P
F
-
Y
I
C
-
S
H
I
N
--
W
G
----
L
----
W
-----
S
L
L
Q
G
---
M
------
H
-----
S
F
-----
D
----------
F
I
N
Y
G
M
T
R
L
T
A
S
C
L
-
P
I
F
R
S
K
V-----
57
HHSearch
68.95
14%
-4
- C7 -
-
5FUT
10
CHKA_HUMAN
A:
[9-374]
------------------------------------------
R
R
--
R
A
Y
L
W
C
-
K
E
F
--
L
-------
P
G
A
W
RGLRE-
D
E
F
H
I
S
V
I
R
G
G
------
L
------
S
N
--
M
L
F
Q
----
C
S
L
P----
D
TTATLGDEPR---
K
V
L
L
---
R
L
----
Y
G
------------------G
A
E
A
M
V
-----------
L
E
S
V
---
M
F
A
I
L
A
E
-
R
S
---
L
---
G
---
P
K
L
Y
--------
G
---
I
------------
F
P
-
Q
------
G
R
L
E
Q
F
I
P
S
R
-
R
----
L
-
D
T
E
E
L
S------
L
P
----
D
--
I
S
A
E
I
A
E
K
-----
M
A
T
F
H
G
----
M
-
K
---
M
P
F
N
-
K
-----------------------------
E
-
P
----
K
----
W
---------
L
F
G
T
M
E
K
Y
L
--------
K
E
V
---------------
L
R
-------------
I
K
FTE
E
S
R
I
-----------
K
K
L
-
H
K
L
L
S
---------
Y
---
N
L
-------------
P
L
E
L
E
N
L
R
S
-----------
L
L
E
---
S
T
P
S
------
P
V
V
------
F
-----
C
H
N
D
C
Q
E
G
N
I
L
L
L
E
G
------
R
-
E
-
N
S
E
K
-------
Q
K
L
--------------
M
L
--------
I
D
F
---
E
Y
S
-----
S
Y
N
----------
Y
----
R
G
F
D
I
G
-------
N
-
H
----------------
F
C
-------------
E
W
M
Y
D
Y
S
YEKYPF
F
R
A
N
I
R
K
------------
Y
P
----
T
---
K
K
Q
Q
-
L
H
F
I
S
S
--------
Y
L
--------
P
A
F
---
Q
NDFENLS
T
E
E
K
S
I
I
K
E
E
M
L
L
E
V
N
R
F
-
A
L
A
-
S
H
F
L
--
W
G
----
L
----
W
-----
S
I
V
Q
A
---
K
ISSI--
E
F----
G
Y
M
D
Y
A
Q
A
----------
R
F
D
A
Y
F
H
Q
K
R
-----------------
37
Fugue
68.71
16%
17
- C7 -
-
1NW1
-
CKA2_CAEEL
A:
[32-426]
G
M
K
E
L
L
S
T
MDLDTDANTI
P
E
L
K
E
R
A
H
M
L
C
A
R
F
L
G
G
A
W
K
T
V
P
L
E
H
--
L
R
I
S
R
I
-
K
G
G
--
M
-------
S
--
N
------
M
L
F
L
C
R
L
S
-
E
V
------
Y
------
P
P
--
I
R
N
E
----
P
-------
N
-------------
K
V
L
L
---
R
V
----
Y
F
N
----------
P
E
----
T
--
E
S
H
L
-----------
V
A
E
S
---
V
I
---
F
T
-
L
L
---
S
---
E
---
R
H
L
G
--------
P
---
K
------------
L
Y
-
G
I
F
-
S
-
G
G
R
L
E
E
Y
I
P
S
R
-
P
----
L
-
S
C
H
E
I
S
------
L
A
----
H
--
M
S
T
K
I
A
K
R
-----
V
A
K
V
H
Q
----
L
-
E
---
V
P
I
W
-
K
-----------------------------
E
-
P
----
D
----
Y
---------
L
C
E
A
L
Q
R
W
L
--------
K
Q
L
---------------
T
G
-------------
T
V
------------------
D
---
A
---
E
---------
H
---
R
F
D
L
PEECGVSSVN
C
L
D
L
A
R
E
L
-
E
-----------
F
-----
L
R
A
H
I
S
L
SKS
P
V
T
------
F
-----
C
H
N
D
L
Q
E
G
N
I
L
L
P
-----------------------
K
R
L
--------------
V
L
--------
I
D
F
---
E
Y
A
-----
S
Y
N
----------
Y
----
R
A
F
D
F
A
-------
N
-
H
F
I
E
W
T
IDYDIDEAPF
Y
K
I
-------------
Q
T
-
E
N
F
P
-----------
E
N
------------
D
Q
----
M
---
L
E
F
F
-
L
N
Y
L
R
E
Q
GNTRENE
L
Y
--------
K
-----
K
-----------------
S
E
D
L
V
Q
E
T
-
L
P
F
-
V
P
V
S
--
H
F
----
F
----
W
G
V
W
G
L
L
Q
V
E
L
---
S
------
P
-----
V
G
F
G
F
A
D
Y
----------
G
R
D
R
L
S
L
Y
F
K
H
K
Q
L
-
L
K
N
L
A
-------
62
HHSearch
66.22
15%
-28
- C7 -
-
3C5I
3
?
D:
[34-355]
----------------------------------------------------------------------------
D
N
L
R
V
K
Q
I
L--------
L
------
T
N
--
Q
L
F
E
----
V
G
L
K
----
E
E
T
A
N
N
Y
NSIRT--
R
V
L
F
---
R
I
----
Y
G
K
----------
H
V
----
D
EL
Y
N
T
I
-----------
S
E
F
E
---
V
Y
K
T
M
S
K
-
Y
K
---
I
---
A
---
P
Q
L
L
--------
N
---
T
------------
F
N
-------
G
G
R
I
E
E
W
L
Y
G
D
-
P
----
L
-
R
I
D
D
L
K
------
N
P
----
T
--
I
L
I
G
I
A
N
V
-----
L
G
K
F
H
T
----
L
-
S
---
R
K
R
H
-
L
P----------------------------
E
-
H
----
W
DRTP
C
---------
I
F
K
M
M
E
K
W
K
--------
N
Q
L
---------------
F
K
-------------
Y
K
NIEKYNC-----------
D
---
I
---
H
K
Y
I
------
K
---
E
S
-------------
D
K
F
I
K
F
M
-
K
-----------
V
Y
S
KSD
N
L
A
N
------
T
I
V
------
F
-----
C
H
N
D
L
Q
E
N
N
I
I
N
T
N
K
----------------------
C
L
--------------
R
L
--------
I
D
F
---
E
Y
S
-----
G
F
N
----------
F
----
L
A
T
D
I
A
-------
N
-
F
----------------
F
I
-------------
E
T
S
I
D
Y
S
VSSYPF
F
E
I
D
K
K
K
------------
Y
I
----
S
---
Y
E
N
R
-
K
L
F
I
T
A
--------
Y
L
--------
S
N
----
Y
L
DKVVPT
P
K
L
I
D
E
----
I
L
E
A
V
E
V
Q
-
A
L
G
-
A
H
L
L
--
W
G
----
F
----
W
-----
S
I
I
R
G
---
Y
QTKSYN
E
F----
D
F
F
L
Y
A
E
Q
----------
R
L
K
M
Y
D
D
Q
-------------------
73
SP3
65.67
21%
-1
- C1 -
-
1FP3
-
RENBP_PIG
A:
[1-402]
------------------
M
E
K
E
R
E
T
L
Q
A
W
K
E
R
V
G
Q
E
L
D
R
V
--
M
A
--
F
W
L
E
H
---------------
S
H
-
D
-----------
R
E
H
-
G
G
------
F
FTCLGR
D
G
--
R
V
Y
D
----
D
LKY
V
W
L
Q
G
-------------
R
Q
V
W
M
Y
C
R
L
----
Y
R
K
----------
L
-----
E
--
R
F
H
R
-----------
P
E
L
L
---
D
A
---
A
K
-
A
G
-------
G
---
E
F
L
L
--------
R
HAR
V
------------
A
P
-
P
E
K
-
K
-
C
A
F
V
L
T
R
-
D
G
R
-
P
----
V
K
V
Q
R
S
I
-------
F
S
----
E
--
C
F
Y
T
M
A
M
N
-----
E
L
W
R
V
-----
T
-
A
---
E
A
R
Y
-
Q
-----------------------------
S
E
A
----
V
----
D
---------
M
M
D
Q
I
V
H
W
V
RED-----
P
S
G
---------------
L
G
-------------
R
P
QLPGAVASES
M
A
V
P
M
---
M
---
L
---
L
---------
C
---
L
V
-------------
E
Q
L
G
E
E
D
-
E
E
L
A
G
R
Y
A
Q
L
G
H
W
-----
C
A
R
R
------
I
L
Q
------
H
-----
V
Q
R
D
G
Q
A
--
V
L
E
N
V
S
------
E
-
D
G
E
E
L
S
-------
G
C
L
GRHQN
P
G
H
A
L
E
A
G
W
F
L
--------
L
R
H
---
S
S
R
-----
S
G
D
----------
A
K
L
R
A
H
V
I
D
T
F
-------
L
-
L
----------------
L
P
F
R
S
G
WDADHGGLF
Y
F
-
Q
D
A
D
-----------
G
L
CPTQLEWAMKL
W
W
P
----
H
---
S
E
A
M
-
I
A
F
L
M
G
--------
Y
S
--------
E
SGD
P
-
A
-----------------
L
L
R
L
F
Y
Q
V
-
A
E
Y
-
T
F
R
Q
FR
D
-----
P
EYGE
W
-----
F
G
Y
L
N
---
R
------
E
-----
G
--
K
V
A
L
T
IKGGPFKGCF
H
V
P
R
C
L
A
M
C
E
E
M
L
S
A
L
L
S
R
L
A
------
71
SP3
65.46
16%
18
- C7 -
-
1J7L
1
KKA3_ENTFL
A:
[2-264]
-------------------------------------
A
K
M
R
I
S
------
P
E
L
-
K
K
L
--
I
-------
E
K
----------
Y
R
C
V
K
D
-
T
E
------
G
------
M
S
P
A
K
V
Y
K
----
L
V
G
EN---
E
-------------
N
L
Y
L
---
K
M
T
D
SR
Y
K
G
----------
T
T
----
Y
--
D
V
-
E
-----------
R
E
K
D
---
M
M
---
L
W
-
L
E
GKL
P
---
V
---
P
K
V
L
--------
H
---
F
------------
E
R
-
H
D
G
-
W
-
S
N
L
L
M
S
E
A
D
G
V
-
L
C
S
E
E
Y
-
E
D
E
Q
S
-------
P
E
----
K
--
I
I
E
L
Y
A
E
C
-----
I
R
L
F
H
S
----
I
-
D
ISD
C
P
Y
T
-
N
-----------------------------
S
-
L
----
D
----
S
---------
R
L
A
E
L
D
Y
L
L
N
N
DLADVD
C
E
N
WEED-----------
T
P
-------------
F
K
------------------
D
---
P
---
R
---------
E
---
L
Y
-------------
D
F
L
K
T
E
K
-
P
-----------
E
-----
E
E
L
V
---------------
F
-----
S
H
G
D
L
G
D
S
N
I
F
V
K
--------------
D
G
-------
K
V
S
--------------
G
F
--------
I
D
L
---
G
R
S
-----
G
R
A
----------
D
----
K
W
Y
D
I
A
-------
F
-
C
----------------
V
R
-------------
S
I
-
R
E
D
I
-----------
G
E
------------
E
Q
----
Y
---
V
E
L
F
-
F
D
L
L
G
I
--------
K
P
--------
D
------------------------
W
E
K
I
K
Y
Y
-
I
L
L
-
D
E
L
F
-------------------------------------------------------------------------------------
33
Fugue
65.30
21%
18
- C7 -
-
1J7L
1
KKA3_ENTFL
A:
[2-264]
----------------------------
A
K
M
R
I
S
P
E
L
K
K
L
I
E
K
Y
--
R
C
V
K
D
T
-
E
G
M
----------
S
P
-
A
------
K
V
Y
K
L
V
G
E
-
N
E
------
N
------
L
Y
--
L
K
M
T
----
D
-------
S
-------------
R
Y
-------------
K
----------
G
T
----
T
--
Y
D
V
E
-----------
R
E
K
D
---
M
M
---
L
W
-
L
E
---
G
---
K
LPV
P
K
V
L
--------
H
---
F
------------
E
R
-
H
D
G
-
W
-
S
N
L
L
M
S
E
A
D
G
V
-
L
----
C
-
S
E
E
Y
E
-------
D
E
QS
P
E
K
--
I
I
E
L
Y
A
E
C
-----
I
R
L
F
H
S
----
I
-
D
---
I
S
D
C
-
P
-----------------------------
Y
-
T
----
N
----
S
---------
L
D
S
R
L
A
E
L
D
--------
Y
L
L
N
N
DLADVDCENWEED
T
P
-------------
F
K
------------------
D
---
P
---
R
---------
E
---
L
Y
-------------
D
F
L
K
T
E
K
-
P
-------------------
E
E
------
E
L
V
------
F
-----
S
H
G
D
L
G
D
S
N
I
F
V
K
--------------
D
G
-------
K
V
S
--------------
G
F
--------
I
D
L
---
G
R
S
-----
G
R
A
----------
D
----
K
W
Y
D
I
A
-------
F
-
C
----------------
V
R
-------------
S
I
-
R
E
D
I
-----------
G
E
------------
E
Q
----
Y
---
V
E
L
F
-
F
D
L
L
G
I
--------
K
P
--------
D
------------------------
W
E
K
I
K
Y
Y
-
I
L
L
-
D
E
L
F
-------------------------------------------------------------------------------------
31
Fugue
64.02
11%
23
- C7 -
-
3I1A
2
?
A:
[3-330]
-------------------------------------
K
Q
P
I
Q
A
Q
--
Q
L
I
E
L
L
-
K
V
H
YG
I
-------
D
I
-
H
------
T
A
Q
F
I
Q
G
G
-
A
D
------
T
------
N
A
--
F
A
Y
Q
A
D
S
E
S
-------
K
-------------
S
Y
F
I
---
K
L
----
K
Y
G
----------
Y
H
----
D
--
E
I
N
L
-----------
S
I
I
R
---
L
L
---
H
D
-
S
G
---
I
---
K
---
E
I
I
F
PIHTLEAK
L
---
F
------------
Q
Q
-
L
K
H
-
F
-
K
I
I
A
Y
P
F
I
H
A
P
-
N
----
G
-
F
T
Q
N
L
-------
T
G
----
K
--
Q
W
K
Q
L
G
K
V
-----
L
R
Q
I
H
E
----
T
-
S
---
V
P
I
S
-
I
Q
Q
Q
LRKEIYSP
K
W
R
E
I
V
R
S
F
Y
NQIEFDNS
D
-
D
----
K
----
L
---------
T
A
A
F
K
S
F
F
N
--------
Q
N
S
---------------
A
A
-------------
I
H
------------------
R
---
L
---
V
---------
D
---
T
S
-------------
E
K
L
S
K
K
I
-
Q
-----------
P
-----
D
L
D
K
------
Y
V
L
------
C
------
H
S
D
I
H
A
G
N
V
L
V
G
--------------
N
E
-------
E
S
I
--------------
Y
I
--------
I
D
W
---
D
E
P
-----
M
L
A
----------
P
----
K
E
R
D
L
M
-------
F
-
I
----------------
G
G
-------------
G
V
-
G
N
V
W
-----------
N
K
------------
P
H
----
E
---
I
Q
Y
F
-
Y
E
G
Y
G
E
--------
I
N
--------
V
-----
D
------------------
K
T
I
L
S
Y
Y
-
R
H
E
-
R
I
V
E
--
D
I
A
V
Y
G
Q
----
D
-----
L
L
S
R
N
---
Q
------
N
-----
N
Q
S
R
L
E
S
F
----------
K
Y
F
K
E
M
F
D
P
N
N
V
V
E
-
I
A
F
A
T
E
------
38
Fugue
62.86
14%
1
- C7 -
-
2Q83
5
COTI_BACSU
A:
[11-346]
--------------------
L
S
A
E
D
A
K
K
L
T
E
L
A
E
N
V
L
Q
G
W
D
V
Q
A
--
E
K
I
D
V
I
-
Q
A
--------------
L
------
V
W
K
V
H
T
D
S
-
G
A
------
V
------
C
L
--
K
R
I
H
----
R
-------
P
-------------
E
K
K
A
---
L
F
----
S
I
F
----------
A
Q
----
D
--
Y
L
A
K
K
GMN
V
P
G
I
L
P
N
K
K
G
S
---
L
Y
---
S
K
-
H
G
---
S
---
F
---
L
F
V
V
--------
Y
---
D
W
I
E
G
R
P
F
E
LTV
K
Q
D
-
L
E
F
-
I
M
K
G
L
A
D
F
H
T
A
S
V
-
G
----
Y
-
Q
P
P
N
G
-------
V
P
----
I
F
T
K
L
G
R
W
P
N
H
-----
Y
T
K
R
C
K
----
Q
M
E
---
T
W
K
L
M
A
-----------------------------
E
-
A
----
E
----
K
---------
E
D
P
F
S
Q
L
Y
L
--------
Q
E
I
---------------
D
G
-------------
F
I
------------------
E
---
D
---
G
---------
L
---
R
I
-------------
K
D
R
L
L
Q
S
-
T
-----------
Y
-----
V
P
W
T
------
E
Q
L
------
K
K
S
P
N
L
C
H
Q
D
Y
G
T
G
N
T
L
L
G
--------------
E
N
-------
E
Q
I
--------------
W
V
--------
I
D
L
---
D
T
V
-----
S
F
D
----------
L
----
P
I
R
D
L
R
-------
K
M
I
----------------
I
P
-------------
L
L
-
D
T
T
G
-----------
V
W
------------
D
D
----
E
---
T
F
N
V
M
L
N
A
Y
E
S
--------
R
---------
A
-----
P
-----------------
L
T
E
E
Q
K
Q
V
M
F
I
D
M
L
F
P
Y
--
E
L
----
Y
----
D
-----
V
I
R
E
K
---
Y
------
V
-----
R
K
S
A
L
P
K
E
----------
E
L
E
S
A
F
E
Y
E
R
I
K
A
N
-
A
L
R
Q
L
I
------
42
Fugue
62.82
21%
-14
* C5 *
-
3WZM
-
?
A:
[15-278]
------------------
M
R
T
R
S
T
I
S
T
P
--
N
G
I
T
W
Y
Y
E
Q
E
G
T
G
P
--
D
V
V
L
V
----------------
P
-
D
------
G
L
G
E
C
Q
M
F
-
D
S
------
S
------
V
S
--
Q
I
A
A
----
Q
-------
G
-------------
F
R
V
T
---
T
F
----
D
M
P
----------
G
M
----
S
--
R
S
A
K
-----------
A
P
P
E
TYT
E
V
---
T
A
-
Q
K
---
L
---
A
---
S
Y
V
I
--------
S
---
V
------------
L
D
-
A
L
D
-------
I
K
H
--
A
T
-
V
----
W
-
G
C
A
S
G
-------
A
S
----
T
--
V
V
A
L
L
L
G
Y
PDRIR
N
A
M
C
H
E
----
L
-
P
---
T
K
-------------------------------------------------------
L
L
D
H
L
S
N
T
A
--------
V
L
-----------------
E
-------------
D
E
------------------
E
---
I
---
S
---------
K
---
I
L
-------------
A
N
V
M
L
N
------------------------------------------------
D
V
S
G
G
S
E
A
W
Q
A
M
------
G
-
D
E
V
H
A
R
-------
L
H
K
--------------
N
Y
--------
P
V
W
---
A
R
G
YPRTI
P
P
S
----------
A
----
P
V
K
D
L
E
-------
A
-
L
----------------
R
G
-------------
K
P
-
L
D
W
T
-----------
V
G
------------
A
A
----
T
---
P
T
E
S
-
F
F
D
N
I
V
--------
T
A
--------
T
-----
K
-----------------
A
G
-------
V
N
I
-
G
L
L
P
--
G
M
----
H
----
F
-----
P
Y
V
S
H
---
P
------
D
-----
V
F
A
K
Y
V
V
E
----------
T
T
Q
K
H
L
---------------------
65
HHSearch
62.46
13%
-15
- C7 -
-
3TDW
1
?
A:
[7-280]
----------------------------------------------
H
Y
T
T
M
I
-
M
T
Q
--
F
-------
P
D
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I
------
S
I
Q
S
V
E
S
L
G
E
G
------
F
------
R
N
--
Y
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L
----
V
N------
G
-------------
D
W
V
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---
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F
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Q
----
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A
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-----------
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---
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L
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L
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---
N
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P
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---
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------------
G
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V
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----
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-
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---
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I
-----------------------------
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V
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----
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---------
L
K
N
K
I
L
L
L
S
--------
E
A
V
---------------
E
D
-------------
Q
V
------------------
F
PLL
D
---
E
S
L
R
------
D
---
Y
L
-------------
T
L
R
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-----------
H
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------
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-----
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------
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L
T
--------------
G
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--------
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D
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---
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D
A
-----
A
I
S
----------
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----
P
D
Y
D
Y
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-------
Y
-
L
----------------
L
E
-------------
D
C
--
G
E
L
------------
F
---------------------------
T
R
Q
V
M
A
--------
Y
R
--------
G
EVD
L
D
T
-----------------
H
I
R
K
V
S
L
F
-
V
T
F
-
D
Q
V
S
--
Y
L
----
L
----
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-----
G
L
R
A
--------------------------------------------------------------