@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKQ2: (2017-10-28 )
MPKIKPIKLVIIVVCIAIIAVLAWKFLKPKQQQPQYITAEVTRGDIENNVLATGTLDATKLISVGAQVSGQVKKMYVQLGDQVKQGQLIAQIDSTTQENSLKTSDANIKNLEAQRLQQVASLNEKQLEYRRQQQMYAQDATPRADLESAEAAYKTAQAQVKALDAQIESAKVTRSTAQTNIGYTRIVAPTDGTVVAIVTEEGQTVNANQSAPTIVKIAKLQNMTIKAQVSEADIMKVEKGQQVYFTTLGDETKRYATLRQIEPAPDSISSESNSTTSSTTSSAVYYNALFDVPNTDGKLRIDMTAQVYIVLNSAKNALLVPSSALSSKQFSGQRKQQGQSADKASSTPSAERKHQGNGARLERLNLTPEQKQLIEQGKATLSVVRVLQADGTTKPTQILVGINNRVNAQVLAGLKQGDQVVIADSSENSAASANSGNNRRRGPMGM
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160......--.170.......180.......190.......200.......210.--......220.......230.......----240--------.--.......250-.--..----.-....260.----......270.......280.......290...-.-----...300.......310.----......320......-.330.......340.......350.......360.......370.......380.......390........400...-....410.......420.......430.......440....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MPKIKP
I
K
L
V
I
I
V
V
C
I
A
I
I
A
V
L
A
W
K
FLKPKQQQP
Q
Y
I
T
A
E
VTRGDIEN
N
V
L
A
TGTL
D
A
T
K
L
I
S
V
G
A
Q
VS
G
Q
V
K
K
M
Y
V
Q
LGDQVKQG
Q
L
I
A
QIDSTTQENSLKTSDANIKN
L
E
A
Q
R
L
Q
Q
V
A
SL
N
E
K
Q
L
E
Y
R
R
Q
Q
Q
M
Y
AQDATPRAD
L
E
S
A
E
A
A
Y
K
T
A
Q
A
Q
V
K
A
L
DAQIE--S
A
K
V
TRSTAQTNI
G
Y
T
R
I
VAPTD
G
T
V
V
A
I
VTEEGQTVNANQSA
P
T
--
I
V
K
I
A
K
LQN
M
T
I
K
A
QVSEA
D
I
M
K
VEK----G
Q
---------
Q
--
V
Y
F
T
TLGD-E-
T
--
K
R
----
Y
-
A
T
LRQIEP----APDSISSESNSTTSSTTS
S
A
V
Y
Y
N
A
L
FDVPNT-D-----
G
K
L
R
I
D
M
T
A
Q
V
Y
I
V
L
NS----AK
N
A
L
L
VPSSALSSK-QFS
G
Q
R
K
QQGQSADKASSTPSAERKHQGNG
A
R
L
E
R
LNL
T
P
E
Q
K
Q
L
I
E
QG
K
A
T
L
S
V
V
R
V
L
QAD-GTTK
P
T
Q
I
L
V
GINNR-V
N
A
Q
V
L
A
GLKQG
D
Q
V
V
I
ADSSENSAASANSGNNRRRGPMGM
60
HHSearch
82.41
41%
-32
- C4 -
-
5NIK
-
?
G:
[32-368]
-------------------------------
P
V
P
T
Y
Q
T
L
I
V
R
P
G
D
L
Q
Q
S
V
L
A
T
G
K
L
D
A
L
R
K
V
D
V
G
A
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V
S
G
Q
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T
L
S
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
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L
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R
Q
Q
A
E
A
E
L
K
L
A
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V
T
Y
S
R
Q
Q
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L
A
Q
T
Q
A
V
S
Q
Q
D
L
D
N
A
A
T
E
M
A
V
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
--
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
A
A
Q
Q
A
P
N
--
I
L
T
L
A
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
--
A
W
F
T
V
L
G
D
-
Q
L
T
--
R
Y
----
E
-
G
Q
I
K
D
V
L
P
----
T
P
E
K
V
------------
N
D
A
I
F
Y
Y
A
R
F
E
V
P
N
P
-
N
-----
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
----
V
K
N
V
L
T
I
P
L
S
A
L
G
D
P
-
V
G
D
N
------------------------------------------------
R
Y
K
V
K
L
L
R
-
N
-
G
E
T
R
E
R
E
V
T
I
G
A
R
N
D
-
T
D
V
E
I
V
K
G
L
E
A
G
D
E
V
V
I
G
E
A
K
P
G
------------------
2
PsiBlast_PDB
79.52
35%
-33
- C4 -
-
5NIL
-
?
D:
[32-370]
-----------------------------
P
V
--
P
T
Y
Q
T
L
I
V
R
P
G
D
L
Q
Q
S
V
L
A
T
G
K
L
D
A
L
R
K
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
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M
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L
R
A
Q
R
Q
Q
A
E
A
E
L
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L
A
R
V
T
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S
R
Q
Q
R
L
A
Q
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Q
A
V
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Q
Q
D
L
D
N
A
A
T
E
M
A
V
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
--
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
A
A
Q
Q
A
P
N
--
I
L
T
L
A
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
--
A
W
F
T
V
L
G
D
-
Q
-
L
--
T
R
----
Y
E
G
Q
I
K
D
V
L
P
----
T
P
E
K
V
------------
N
D
A
I
F
Y
Y
A
R
F
E
V
P
N
P
-
N
-----
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
----
V
K
N
V
L
T
I
P
L
S
A
L
G
D
---------------------
P
V
G
D
N
R
Y
K
----------------------------
V
K
L
L
R
-
N
-
G
E
T
R
E
R
E
V
T
I
G
A
R
N
D
-
T
D
V
E
I
V
K
G
L
E
A
G
D
E
V
V
I
G
E
A
K
P
G
A
A
----------------
1
PsiBlast_PDB
79.52
35%
-33
- C4 -
-
5NIK
-
?
D:
[32-370]
-----------------------------
P
V
--
P
T
Y
Q
T
L
I
V
R
P
G
D
L
Q
Q
S
V
L
A
T
G
K
L
D
A
L
R
K
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
E
L
R
A
Q
R
Q
Q
A
E
A
E
L
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
Q
T
Q
A
V
S
Q
Q
D
L
D
N
A
A
T
E
M
A
V
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
--
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
A
A
Q
Q
A
P
N
--
I
L
T
L
A
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
--
A
W
F
T
V
L
G
D
-
Q
-
L
--
T
R
----
Y
E
G
Q
I
K
D
V
L
P
----
T
P
E
K
V
------------
N
D
A
I
F
Y
Y
A
R
F
E
V
P
N
P
-
N
-----
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
----
V
K
N
V
L
T
I
P
L
S
A
L
G
D
---------------------
P
V
G
D
N
R
Y
K
----------------------------
V
K
L
L
R
-
N
-
G
E
T
R
E
R
E
V
T
I
G
A
R
N
D
-
T
D
V
E
I
V
K
G
L
E
A
G
D
E
V
V
I
G
E
A
K
P
G
A
A
----------------
81
Fugue
74.44
45%
-57
- C4 -
-
3FPP
-
MACA_ECOLI
A:
[43-308]
------------------------------------------
P
G
D
L
Q
Q
S
V
L
A
T
G
K
L
D
A
L
R
K
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
E
L
R
A
Q
R
Q
Q
A
E
A
E
L
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
Q
T
Q
A
V
S
Q
Q
D
L
D
N
A
A
T
E
M
A
V
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
--
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
A
A
Q
Q
A
P
N
--
I
L
T
L
A
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
--
A
W
F
T
V
L
G
D
-
Q
-
L
--
T
R
----
Y
E
G
Q
I
K
D
V
L
P
----
T
P
E
------------
K
V
N
D
A
I
F
Y
Y
A
R
F
E
V
P
N
P
-
N
-----
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
----
V
K
N
V
L
T
----------------------------------------------------------------------------------------------------------------------------------
61
HHSearch
70.76
42%
-47
- C4 -
-
3FPP
-
MACA_ECOLI
B:
[42-308]
-----------------------------------------
R
P
G
D
L
Q
Q
S
V
L
A
T
G
K
L
D
A
L
R
K
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V
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A
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G
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S
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A
I
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K
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D
Q
L
L
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E
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A
E
N
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I
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E
V
E
A
T
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M
E
L
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A
Q
R
Q
Q
A
E
A
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L
A
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Y
S
R
Q
Q
R
L
A
Q
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A
V
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Q
Q
D
L
D
N
A
A
T
E
M
A
V
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
--
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
T
R
I
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A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
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I
A
A
Q
Q
A
P
N
--
I
L
T
L
A
D
M
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A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
--
A
W
F
T
V
L
G
D
-
Q
L
T
--
R
Y
----
E
-
G
Q
I
K
D
V
L
P
----
T
P
E
K
V
------------
N
D
A
I
F
Y
Y
A
R
F
E
V
P
N
P
-
N
-----
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
----
V
K
N
V
L
T
----------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
70.33
35%
-57
- C4 -
-
3FPP
-
MACA_ECOLI
A:
[43-308]
------------------------------------------
P
G
D
L
Q
Q
S
V
L
A
T
G
K
L
D
A
L
R
K
V
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V
G
A
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G
Q
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D
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A
E
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Q
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E
A
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E
L
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A
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R
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Q
A
E
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A
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A
A
T
E
M
A
V
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Q
A
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G
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I
D
A
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--
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A
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--
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M
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A
M
L
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K
A
Q
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S
E
A
D
V
I
H
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P
----
G
Q
---------
K
--
A
W
F
T
V
L
G
D
-
Q
-
L
--
T
R
----
Y
E
G
Q
I
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D
V
L
P
----
T
P
E
K
V
------------
N
D
A
I
F
Y
Y
A
R
F
E
V
P
N
P
-
N
-----
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
----
V
K
N
V
L
T
----------------------------------------------------------------------------------------------------------------------------------
68
HHSearch
58.10
41%
-81
- C4 -
-
4DK1
-
MEXA_PSEAE
A:
[34-332]
-------------------------------------
T
E
E
V
K
R
G
N
I
E
K
N
V
V
A
T
G
S
I
E
S
I
N
T
V
D
V
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A
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V
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G
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Y
V
K
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G
Q
Q
V
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K
G
D
L
L
A
E
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D
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A
T
Y
E
A
D
Y
Q
S
A
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A
N
L
A
S
T
Q
--------------
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
--------------
A
Y
L
--
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
I
T
S
P
I
D
G
T
V
I
S
T
P
V
S
E
G
Q
T
V
N
S
N
Q
T
T
P
T
--
I
I
K
V
A
D
L
S
K
M
R
I
K
P
E
I
S
E
G
D
I
T
K
V
K
A
----
G
Q
---------
D
--
V
T
F
T
I
L
S
D
-
N
K
T
--
V
Y
----
H
-
A
K
I
D
S
V
D
P
----
A
T
T
T
I
S
D
-----------
S
A
V
Y
Y
Y
A
N
I
I
V
E
N
P
-
E
-----
H
V
L
R
I
G
M
T
T
E
N
N
I
K
I
A
D
----
V
Q
N
V
L
F
I
P
N
L
A
V
Q
--------------------------------------------------------------------------
E
I
G
V
Q
N
D
-
F
Q
T
E
V
K
S
G
L
T
E
G
E
K
V
V
I
S
-----------------------
62
HHSearch
55.96
42%
-17
* C4 *
-
4DK0
-
?
A:
[32-378]
-----------------------------------
Y
L
T
E
E
V
K
R
G
N
I
E
K
N
V
V
A
T
G
S
I
E
S
I
N
T
V
D
V
G
A
Q
V
S
G
K
I
T
K
L
Y
V
K
L
G
Q
Q
V
K
K
G
D
L
L
A
E
I
D
S
T
T
Q
I
N
T
L
N
T
R
K
A
A
L
A
S
Y
Q
A
Q
L
V
A
R
K
T
A
Y
D
V
A
L
S
N
Y
Q
R
L
S
K
L
Y
G
Q
K
A
T
S
L
D
T
L
N
T
A
K
A
T
L
N
N
A
K
A
E
M
D
V
V
Q
E
N
I
K
--
Q
A
E
I
E
V
N
T
A
E
T
N
L
G
Y
T
K
I
T
S
P
I
D
G
T
V
I
S
T
P
V
S
E
G
Q
T
V
N
S
N
Q
T
T
P
T
--
I
I
K
V
A
D
L
S
K
M
R
I
K
P
E
I
S
E
G
D
I
T
K
V
K
A
----
G
Q
---------
D
--
V
T
F
T
I
L
S
D
-
N
K
T
--
V
Y
----
H
-
A
K
I
D
S
V
D
P
----
A
T
T
T
I
S
D
-----------
S
A
V
Y
Y
Y
A
N
I
I
V
E
N
P
-
E
-----
H
V
L
R
I
G
M
T
T
E
N
N
I
K
I
A
D
----
V
Q
N
V
L
F
I
P
N
L
A
V
Q
---
Q
D
--------------------------------------------------
K
Y
V
V
N
V
L
N
----
T
T
Q
E
R
E
I
E
I
G
V
Q
N
D
-
F
Q
T
E
V
K
S
G
L
T
E
G
E
K
V
V
I
S
Q
----------------------
8
PsiBlast_PDB
55.13
22%
-94
- C4 -
-
4L8J
3
?
A:
[26-194]
----------------------------------------------------
S
G
M
V
E
A
V
E
Y
V
K
L
A
F
R
V
S
G
Q
I
I
N
L
P
V
V
E
G
Q
R
V
K
K
G
Q
L
I
A
A
I
D
P
--------------
R
D
I
S
L
Q
Y
A
A
D
K
A
A
Y
E
T
A
A
A
Q
V
E
R
N
K
R
L
L
G
R
Q
A
I
S
L
Q
E
Y
E
I
S
V
A
N
Y
--------------
Q
--
K
A
K
S
A
Y
E
L
S
T
N
N
M
R
D
T
K
L
L
A
P
F
D
G
S
I
E
T
R
L
V
E
N
Y
Q
R
V
N
S
G
E
G
-----
I
V
R
L
V
N
T
R
K
L
R
I
K
F
T
V
P
D
-
D
Y
L
Y
L
L
R
----
A
K
---------
D
--
A
T
F
K
V
E
F
D
-
T
-
Y
--
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
54.48
33%
-81
- C4 -
-
4DK1
-
MEXA_PSEAE
A:
[34-332]
-------------------------------------
T
E
E
V
K
R
G
N
I
E
K
N
V
V
A
T
G
S
I
E
S
I
N
T
V
D
V
G
A
Q
V
S
G
K
I
T
K
L
Y
V
K
L
G
Q
Q
V
K
K
G
D
L
L
A
E
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
--------------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
----------------
A
R
I
N
L
R
Y
T
K
I
T
S
P
I
D
G
T
V
I
S
T
P
V
S
E
G
Q
T
V
N
S
N
Q
T
T
P
T
--
I
I
K
V
A
D
L
S
K
M
R
I
K
P
E
I
S
E
G
D
I
T
K
V
K
A
----
G
Q
---------
D
--
V
T
F
T
I
L
S
D
N
K
-
T
--
V
Y
----
H
-
A
K
I
D
S
V
D
P
----
A
T
T
T
I
S
D
-----------
S
A
V
Y
Y
Y
A
N
I
I
V
E
N
P
-
E
-----
H
V
L
R
I
G
M
T
T
E
N
N
I
K
I
A
D
----
V
Q
N
V
L
F
I
P
N
L
A
V
---------
Q
-----------------------------------------------------------------
E
I
G
V
Q
N
D
-
F
Q
T
E
V
K
S
G
L
T
E
G
E
K
V
V
I
S
-----------------------
69
HHSearch
54.42
20%
-32
- C4 -
-
4L8J
5
?
A:
[7-325]
--------------------------------
V
R
P
V
K
T
A
T
V
S
S
Q
S
V
I
-
L
K
D
F
S
G
M
V
E
A
V
E
Y
V
K
L
A
F
R
V
S
G
Q
I
I
N
L
P
V
V
E
G
Q
R
V
K
K
G
Q
L
I
A
A
I
D
P
R
D
I
S
L
Q
Y
A
A
D
K
A
--------------
A
Y
E
T
A
A
A
Q
V
E
R
N
K
R
L
L
G
R
Q
A
I
S
L
Q
E
Y
E
I
S
V
A
N
Y
Q
K
----------------
A
K
S
A
Y
E
L
S
T
N
N
M
R
D
T
K
L
L
A
P
F
D
G
S
I
E
T
R
L
V
E
N
Y
Q
R
V
N
S
G
E
---
G
--
I
V
R
L
V
N
T
R
K
L
R
I
K
F
T
V
P
D
D
Y
L
Y
L
L
R
A
----
K
D
A
--------
T
--
F
K
V
E
F
D
T
Y
-
K
G
T
--
V
F
----
N
-
A
R
L
E
E
Y
L
D
----
I
S
T
D
G
---------------
T
G
I
P
V
T
I
I
I
D
D
A
-
A
FDRTI
Y
D
V
K
P
G
F
T
C
N
I
R
L
A
S
D
I
APFI
E
E
K
L
M
N
V
P
L
S
A
V
F
G
D
-
S
E
N
K
------------------------------------------------
N
T
Y
V
W
I
V
K
-
D
-
N
K
V
N
R
R
E
V
T
V
Y
S
P
T
G
E
A
N
L
L
I
S
K
G
L
K
P
G
E
T
V
V
T
A
G
V
Y
Q
L
V
E
G
Q
R
I
K
-----------
4
PsiBlast_PDB
52.83
36%
-17
- C4 -
-
4DK0
-
?
A:
[32-377]
-----------------------------------
Y
L
T
E
E
V
K
R
G
N
I
E
K
N
V
V
A
T
G
S
I
E
S
I
N
T
V
D
V
G
A
Q
V
S
G
K
I
T
K
L
Y
V
K
L
G
Q
Q
V
K
K
G
D
L
L
A
E
I
D
S
T
T
Q
I
N
T
L
N
T
R
K
A
A
L
A
S
Y
Q
A
Q
L
V
A
R
K
T
A
Y
D
V
A
L
S
N
Y
Q
R
L
S
K
L
Y
G
Q
K
A
T
S
L
D
T
L
N
T
A
K
A
T
L
N
N
A
K
A
E
M
D
V
V
Q
E
N
I
K
--
Q
A
E
I
E
V
N
T
A
E
T
N
L
G
Y
T
K
I
T
S
P
I
D
G
T
V
I
S
T
P
V
S
E
G
Q
T
V
N
S
N
Q
T
T
P
T
--
I
I
K
V
A
D
L
S
K
M
R
I
K
P
E
I
S
E
G
D
I
T
K
V
K
A
----
G
Q
---------
D
--
V
T
F
T
I
L
S
D
N
K
-
T
--
V
Y
----
H
-
A
K
I
D
S
V
D
P
----
A
T
T
T
I
S
D
-----------
S
A
V
Y
Y
Y
A
N
I
I
V
E
N
P
-
E
-----
H
V
L
R
I
G
M
T
T
E
N
N
I
K
I
A
D
----
V
Q
N
V
L
F
I
P
N
L
A
V
---------
Q
--
Q
----
D
K
--------------------------------------
Y
V
V
N
V
L
N
----
T
T
Q
E
R
E
I
E
I
G
V
Q
N
D
-
F
Q
T
E
V
K
S
G
L
T
E
G
E
K
V
V
I
S
-----------------------
71
HHSearch
52.78
19%
-60
- C4 -
-
4KKS
-
?
A:
[23-283]
-------------------------------
Y
R
F
P
V
I
A
M
K
V
K
K
G
I
L
S
D
Y
L
S
L
N
G
D
V
D
T
K
V
K
A
D
I
F
P
D
A
V
G
K
I
T
S
L
R
I
K
L
G
A
Y
V
Q
K
G
Q
I
V
A
T
L
D
P
S
R
P
G
S
----------------------------------------------------------------------------------
V
Y
L
K
S
P
V
R
A
P
I
S
G
Y
I
L
N
I
T
K
K
I
G
E
T
V
N
P
Q
S
---
N
--
I
A
V
V
G
R
I
D
T
K
Q
I
L
T
Y
V
S
E
K
Y
I
S
N
I
K
V
----
G
N
---------
D
--
A
I
I
E
V
G
A
Y
-
S
N
E
--
K
F
----
K
-
A
K
V
S
E
I
S
P
----
I
L
D
S
K
--------------
S
R
T
I
E
V
Y
L
T
P
I
G
S
N
L
-----
D
K
L
I
I
G
M
F
S
K
I
K
L
I
T
K
R
----
F
K
D
V
I
K
I
S
R
E
A
V
V
E
R
-
E
G
--------------------------------------------------
K
K
F
V
F
K
V
D
L
E
S
K
S
V
Q
M
L
P
I
T
V
L
F
E
I
D
-
N
I
V
A
L
S
G
E
V
E
E
N
D
L
I
V
V
E
G
M
S
A
L
S
N
G
S
L
I
N
L
----------
14
PsiBlast_PDB
51.61
23%
-29
- C4 -
-
5V5S
-
ACRA_ECOLI
D:
[58-314]
-----------------------------------------------------
G
R
T
S
A
Y
R
I
A
E
V
R
P
Q
V
S
G
I
I
L
K
R
N
F
K
E
G
S
D
I
E
A
G
V
S
L
Y
Q
I
D
P
A
T
Y
Q
A
T
Y
D
S
A
K
G
D
L
A
-------
K
A
Q
A
A
A
N
I
A
Q
L
T
V
N
R
Y
Q
K
L
L
G
T
Q
Y
I
S
K
Q
E
Y
D
Q
A
L
A
D
A
Q
Q
A
N
A
A
V
T
A
A
K
A
A
V
E
--
T
A
R
I
-------
N
L
A
Y
T
K
V
T
S
P
I
S
G
R
I
G
K
S
N
V
T
E
G
A
L
V
Q
-
N
G
Q
A
T
A
--
L
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
S
S
N
D
F
L
R
L
K
------
Q
---------
E
--
L
A
N
G
T
L
K
Q
-
E
-
N
--
G
K
------
A
K
V
S
L
I
T
S
DGIK
F
P
Q
D
G
T
L
E
F
S
D
V
T
V
D
Q
T
T
G
C
I
T
L
R
A
I
F
--
P
N
P
-
D
-----
H
T
L
L
P
G
M
F
V
R
A
R
L
E
E
G
L
----
N
P
N
A
I
L
V
P
Q
Q
G
V
T
---------------------------------------------------------------------------------------------------------------------------
84
Fugue
51.50
19%
-74
- C4 -
-
1T5E
1
MEXA_PSEAE
A:
[29-259]
-------------------------------------------------
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
--------------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
----------------
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
A
-
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
----
E
L
---------
A
--
S
G
Q
L
E
R
A
G
-
D
-
N
--
A
A
----
K
-
V
S
L
K
L
E
D
G
----
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
P
N
P
-
N
-----
N
E
L
L
P
G
M
F
V
H
A
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------
67
HHSearch
51.36
20%
-10
- C4 -
-
2V4D
-
MEXA_PSEAE
G:
[13-337]
---------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
--------------
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
----------------
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
---
A
NA
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
ELAS
G
Q
LERAGDNAA
K
--
V
S
L
K
L
E
D
G
-
S
Q
Y
--
P
L
----
E
-
G
R
L
E
F
S
E
V
----
S
V
D
E
G
--------------
T
G
S
V
T
I
R
A
V
F
P
N
P
-
N
-----
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
----
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
--------------------------------------------------
Q
A
T
A
L
V
V
N
A
Q
-
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
-
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
----------
73
HHSearch
50.13
22%
-52
- C4 -
-
2F1M
-
ACRA_ECOLI
D:
[54-297]
-------------------------------------------------
T
E
L
P
G
R
T
S
A
Y
R
I
A
E
V
R
P
Q
V
S
G
I
I
L
K
R
N
F
K
E
G
S
D
I
E
A
G
V
S
L
Y
Q
I
D
P
A
T
Y
Q
A
T
Y
D
S
A
K
G
D
L
A
K
A
Q
-------
A
A
A
N
I
A
Q
L
T
V
N
R
Y
Q
K
L
L
G
T
Q
Y
I
S
K
Q
E
Y
D
Q
A
L
A
D
A
Q
Q
A
N
A
-------
A
V
T
--
A
A
K
A
A
V
E
T
A
R
I
N
L
A
Y
T
K
V
T
S
P
I
S
G
R
I
G
K
S
N
V
T
E
G
A
L
V
Q
N
G
Q
-
A
T
A
--
L
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
S
--------------
G
---------
K
--
A
K
V
S
L
I
T
S
-
D
G
I
KF
P
Q
----
D
-
G
T
L
E
F
S
D
V
----
T
V
D
Q
T
--------------
T
G
S
I
T
L
R
A
I
F
P
N
P
-
D
-----
H
T
M
M
P
G
M
F
V
R
A
R
L
------------------------------------------------------------------------------------------------------------------------------------------------
65
HHSearch
49.62
20%
-32
- C4 -
-
1VF7
-
MEXA_PSEAE
J:
[26-260]
----------------------------------------------
T
L
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
--------------
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
----------------
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
G
Q
---
A
NA
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
ELAS
G
Q
LERAGDNAA
K
--
V
S
L
K
L
E
D
G
-
S
Q
Y
--
P
L
----
E
-
G
R
L
E
F
S
E
V
----
S
V
D
E
G
--------------
T
G
S
V
T
I
R
A
V
F
P
N
P
-
N
-----
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
-----------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
49.60
23%
-23
- C4 -
-
5NG5
-
ACRA_ECOLI
E:
[34-290]
-----------------------------------------------------
G
R
T
S
A
Y
R
I
A
E
V
R
P
Q
V
S
G
I
I
L
K
R
N
F
K
E
G
S
D
I
E
A
G
V
S
L
Y
Q
I
D
P
A
T
Y
Q
A
T
Y
D
S
A
K
G
D
L
A
K
-------
A
Q
A
A
A
N
I
A
Q
L
T
V
N
R
Y
Q
K
L
L
G
T
Q
Y
I
S
K
Q
E
Y
D
Q
A
L
A
D
A
Q
Q
A
N
A
A
V
T
A
A
K
A
A
V
E
--
T
A
R
I
-------
N
L
A
Y
T
K
V
T
S
P
I
S
G
R
I
G
K
S
N
V
T
E
G
A
L
V
Q
-
N
G
Q
A
T
A
--
L
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
S
S
N
D
M
M
R
L
K
------
Q
---------
E
--
L
A
N
G
T
L
K
Q
-
E
-
N
--
G
K
AKVS
L
-
I
T
S
D
G
I
K
F
----
P
Q
D
G
T
L
E
F
S
D
V
T
V
D
Q
T
T
G
S
-
I
T
L
R
A
I
F
--
P
N
P
-
D
-----
H
T
M
M
P
G
M
F
V
R
A
R
L
E
E
G
L
----
N
P
N
A
I
L
V
P
Q
Q
G
V
T
---------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
49.17
24%
6
- C4 -
-
3LNN
-
?
A:
[45-300]
------------------------------------------------
N
L
P
A
M
I
E
A
D
P
A
K
L
V
K
V
L
P
P
L
A
G
R
I
V
S
L
N
K
Q
L
G
D
E
V
K
A
G
D
V
L
F
T
I
D
S
---------
A
D
L
A
Q
A
N
S
D
A
A
K
A
R
A
A
M
T
M
A
R
R
N
L
D
--
R
Q
R
E
L
D
K
S
E
I
A
A
K
R
D
F
E
Q
A
Q
S
D
Y
D
Q
A
A
S
E
S
Q
R
A
D
A
R
L
A
Q
L
G
A
K
G
G
G
T
L
Q
A
G
G
G
H
I
L
A
V
R
S
P
I
N
G
R
V
V
D
L
N
A
A
T
G
--
A
Y
W
N
D
T
T
A
S
--
L
M
T
V
A
D
L
S
H
V
F
V
T
A
N
A
Q
E
K
D
L
G
H
V
Y
V
----
G
Q
---------
S
A
T
V
K
F
D
A
Y
D
D
---------------------
P
----
Q
P
G
K
V
R
Y
V
G
Q
I
L
D
A
D
T
R
T
T
K
V
--
R
M
V
F
D
--
N
P
-
D
-----
G
R
L
R
P
G
M
F
A
Q
A
T
F
-
L
S
Q
----
P
H
E
G
I
V
V
P
M
S
A
I
V
Q
S
-
G
F
----------------------------------------------------------------------------------------------------------------------