@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VUA3: (2017-12-17 )
MNKPLLLVFHPDLSQSKVNRALVATLKDQDKIDIVDIQKLYNGSLDIMNDGAIEAQRLISASHIILQFPIYWYSVPPIFKAWMDAVLTRMFYLFYEQEGQHIEGKPLYLHITVGNLSSAYQKLGQNGFTLDELMAPLKATARRCGLIWHPPHVIFNANQLNENDITEQTSLSLKQFEQWGIFNNNSFILVLSQKKRTSEKSEVRTML
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........-10.----.----.--..-...20........-30.........40----------------------------.-....----------------------------.---------------------------...50........60..--......70........80........90.....--.-------------..100.........110.......120..--.....130...-.-...140.......150--........160.......170.......180.......190.......200.....-------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNK
P
L
L
L
V
F-HPD----L----
S
--
Q
S
-
K
V
N
R
A
L
V
A
TLKDQ-D-KI
D
I
V
D
I
Q
K
L
-----------------------------Y-NGS
L
----------------------------
D
---------------------------IMNDG
A
I
E
A
Q
R
L
ISA
S
H
--
I
I
L
QF
P
I
Y
W
YSV
P
P
I
F
K
A
W
M
D
A
V
L
T
R
M
F
Y
L
F
YE--Q-------------EGQ--HIEGK
P
L
Y
L
H
I
T
VG
N
L
S
S
A
Y
Q
K
LG--QNGF
T
L
D
E
L
M
A
-
P
-
L
K
A
T
A
R
RCGLIWHPP---
H
V
I
F
NANQLNENDIT
E
Q
T
S
L
S
L
K
Q
F
E
Q
WGIFNN
N
S
F
I
L
V
LSQKKRTS
E
K
S
E
V
R
TML-------
4
PsiBlast_PDB
89.29
30%
-173
- C2 -
-
3L9W
1
KEFC_ECOLI (first)
A:
[240-407]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
I
Y
A
-
H
P
Y
----
P
----
H
--
H
S
-
H
A
N
K
R
M
---
L
E
Q
A
-
R
-
T
L
E
G
V
E
I
R
S
L
-----------------------------
Y
-
Q
L
Y
P
----------------------------
D
---------------------------
F
N
I
D
I
A
A
E
Q
E
A
L
S
R
A
D
L
--
I
V
W
Q
H
P
M
Q
W
Y
S
I
P
P
L
L
K
L
W
I
D
K
V
F
S
H
G
W
A
--
Y
G
--
H
-------------
G
G
T
--
A
L
H
G
K
H
L
L
W
A
V
T
T
G
G
G
E
S
H
F
E
I
G
A
--
H
P
G
F
--
D
V
L
S
Q
-
P
-
L
Q
A
T
A
I
Y
C
G
L
N
W
L
P
P
---
F
A
M
H
C
T
F
I
C
D
D
E
T
L
E
G
Q
A
R
H
Y
K
Q
R
L
L
E
W
-----------------------------------
5
PsiBlast_PDB
87.96
30%
-169
- C2 -
-
3L9X
1
KEFC_ECOLI (first)
A:
[240-407]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
I
Y
A
-
H
P
Y
----
P
----
H
--
H
S
-
H
A
N
K
R
M
---
L
E
Q
A
-
R
-
T
L
E
G
V
E
I
R
S
L
-----------------------------
Y
-
Q
L
Y
P
----------------------------
D
---------------------------
F
N
I
D
I
A
A
E
Q
E
A
L
S
R
A
D
L
--
I
V
W
Q
H
P
M
Q
W
Y
S
I
P
P
L
L
K
L
W
I
D
K
V
F
S
H
G
W
A
--
Y
G
--
H
-------------
G
G
T
--
A
L
H
G
K
H
L
L
W
A
V
T
T
G
G
G
E
S
H
F
E
I
G
A
--
H
P
G
F
--
D
V
L
S
Q
-
P
-
L
Q
A
T
A
I
Y
C
G
L
N
W
L
P
P
---
F
A
M
H
C
T
F
I
C
D
D
E
T
L
E
G
Q
A
R
H
Y
K
Q
R
L
L
E
W
-----------------------------------
3
PsiBlast_PDB
87.39
30%
-164
- C2 -
-
3EYW
1
KEFC_ECOLI (first)
A:
[240-407]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
I
Y
A
-
H
P
Y
----
P
----
H
--
H
S
-
H
A
N
K
R
M
---
L
E
Q
A
-
R
-
T
L
E
G
V
E
I
R
S
L
-----------------------------
Y
-
Q
L
Y
P
----------------------------
D
---------------------------
F
N
I
D
I
A
A
E
Q
E
A
L
S
R
A
D
L
--
I
V
W
Q
H
P
M
Q
W
Y
S
I
P
P
L
L
K
L
W
I
D
K
V
F
S
H
G
W
A
--
Y
G
--
H
-------------
G
G
T
--
A
L
H
G
K
H
L
L
W
A
V
T
T
G
G
G
E
S
H
F
E
I
G
A
--
H
P
G
F
--
D
V
L
S
Q
-
P
-
L
Q
A
T
A
I
Y
C
G
L
N
W
L
P
P
---
F
A
M
H
C
T
F
I
C
D
D
E
T
L
E
G
Q
A
R
H
Y
K
Q
R
L
L
E
W
-----------------------------------
126
HHSearch
86.44
27%
-175
- C2 -
-
3L9W
1
KEFC_ECOLI
B:
[185-406]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
M
I
L
I
I
Y
A
-
H
P
Y
----
P
----
H
--
H
S
-
H
A
N
K
R
M
L
E
Q
A
R
T
L
-
E
-
G
V
E
I
R
S
L
Y
Q
L
-----------------------------
Y
--
P
------------------------------
D
---------------------------
F
N
I
D
I
A
A
E
Q
E
A
L
S
R
A
D
L
--
I
V
W
Q
H
P
M
Q
W
Y
S
I
P
P
L
L
K
L
W
I
D
K
V
F
S
H
G
W
A
Y
G
H
-----------------
G
G
T
--
A
L
H
G
K
H
L
L
W
A
V
T
T
G
G
G
E
S
H
F
E
I
G
A
----
H
P
G
F
D
V
L
S
Q
-
P
-
L
Q
A
T
A
I
Y
C
G
L
N
W
L
P
P
---
F
A
M
H
C
T
F
I
C
D
D
E
T
L
E
G
Q
A
R
H
Y
K
Q
R
L
L
E
------------------------------------
105
Fugue
84.74
28%
-11
- C2 -
-
3EYW
2
KEFC_ECOLI (first)
B:
[5-411]
M
R
V
I
I
A
G
FG
R
F
G
Q
I
T
G
R
L
L
L
S
S
G
V
K
M
V
V
L
D
HDPDH
I
E
T
L
R
K
F
GMKVFYGDATR
M
D
L
L
E
S
A
GAAKAEVLINAIDD
P
Q
T
N
L
Q
L
T
E
M
V
K
E
HFPH
L
Q
I
I
A
R
A
RD
V
D
H
Y
I
R
L
R
Q
A
GVEKPERET
F
E
G
A
L
K
T
G
R
L
A
L
E
S
L
GLG
P
Y
E
A
R
E
R
A
D
V
F
R
R
F
N
I
Q
M
V
E
E
M
A
M
V
END
T
K
A
R
A
A
V
Y
K
R
T
S
A
M
I
L
I
I
Y
A
-
H
P
Y
----
P
----
H
--
H
S
-
H
A
N
K
R
M
L
E
Q
A
R
T
L
-
E
-
G
V
E
I
R
S
L
Y
Q
L
-----------------------------
Y
-
P
-------------------------------
D
---------------------------
F
N
I
D
I
A
A
E
Q
E
A
L
S
R
A
D
L
--
I
V
W
Q
H
P
M
Q
W
Y
S
I
P
P
L
L
K
L
W
I
D
K
V
F
S
H
G
W
A
--
Y
G
--
H
-------------
G
G
T
--
A
L
H
G
K
H
L
L
W
A
V
T
T
G
G
G
E
S
H
F
E
I
G
A
--
H
P
G
--
F
D
V
L
S
Q
-
P
-
L
Q
A
T
A
I
Y
C
G
L
N
W
L
P
P
---
F
A
M
H
C
T
F
I
C
-------------------------------
D
D
E
T
L
E
G
Q
A
R
H
Y
K
Q
R
L
L
E
W
Q
E
A
H
21
PsiBlast_CBE
82.80
33%
-87
- C2 -
-
5LVA
1
?
B:
[3-164]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
V
L
A
F
-
H
P
N
----
M
----
E
--
Q
S
-
V
V
N
R
A
F
A
D
T
L
K
D
A
-
P
-
G
I
T
L
R
D
L
Y
Q
E
-----------------------------
Y
P
D
E
A
I
----------------------------
D
---------------------------
V
------
E
K
E
Q
K
L
C
E
E
H
D
R
I
V
F
Q
F
P
L
Y
W
Y
S
S
P
P
L
L
K
K
W
L
D
H
V
L
--
L
Y
G
W
A
Y
G
--
T
-------------
N
G
T
--
A
L
R
G
K
E
F
M
V
A
V
S
A
G
A
P
E
E
A
Y
Q
A
G
G
--
S
N
H
Y
A
I
S
E
L
L
R
-
P
-
F
Q
A
T
S
N
F
I
G
T
T
Y
L
P
P
---
Y
V
F
Y
Q
A
G
T
A
G
K
S
E
L
A
E
G
A
T
--------------------------------------------
112
HHSearch
82.52
35%
-96
- C2 -
-
5LVA
1
?
B:
[3-161]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
V
L
A
F
-
H
P
N
----
M
----
E
--
Q
S
-
V
V
N
R
A
F
A
D
T
L
K
D
A
-
P
-
G
I
T
L
R
D
L
Y
Q
E
-----------------------------
Y
P
D
-----------------------------------------------------------
E
A
I
D
V
E
K
E
Q
K
L
C
E
E
H
D
R
--
I
V
F
Q
F
P
L
Y
W
Y
S
S
P
P
L
L
K
K
W
L
D
H
V
L
L
Y
G
W
A
Y
G
T
-----------------
N
G
T
--
A
L
R
G
K
E
F
M
V
A
V
S
A
G
A
P
E
E
A
Y
Q
A
G
G
--
S
N
H
Y
A
I
S
E
L
L
R
-
P
-
F
Q
A
T
S
N
F
I
G
T
T
Y
L
P
P
---
Y
V
F
Y
Q
A
G
T
A
G
K
S
E
L
A
E
-----------------------------------------------
113
HHSearch
82.30
35%
-91
- C2 -
-
5LVA
2
?
A:
[1-161]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
L
V
L
A
F
-
H
P
N
----
M
----
E
--
Q
S
-
V
V
N
R
A
F
A
D
T
L
K
D
A
-
P
-
G
I
T
L
R
D
L
Y
Q
E
-----------------------------
Y
P
D
-----------------------------------------------------------
E
A
I
D
V
E
K
E
Q
K
L
C
E
E
H
D
R
--
I
V
F
Q
F
P
L
Y
W
Y
S
S
P
P
L
L
K
K
W
L
D
H
V
L
L
Y
G
W
A
Y
G
T
-----------------
N
G
T
--
A
L
R
G
K
E
F
M
V
A
V
S
A
G
A
P
E
E
A
Y
Q
A
G
G
--
S
N
H
Y
A
I
S
E
L
L
R
-
P
-
F
Q
A
T
S
N
F
I
G
T
T
Y
L
P
P
---
Y
V
F
Y
Q
A
G
T
A
G
K
S
E
L
A
E
-----------------------------------------------
116
HHSearch
81.05
24%
-70
- C2 -
-
4GI5
5
?
A:
[22-232]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
K
V
L
L
I
Y
A
-
H
P
E
----
P
----
R
S
L
N
G
-
A
L
K
N
F
A
I
R
H
L
Q
Q
A
G
H
-
E
V
Q
V
S
D
L
Y
A
M
-----------------------------
R
W
K
A
G
Y
----------------------------
D
ADDSGAPPVGEFWRPT
L
D
S
K
Q
A
F
A
Q
GT
Q
S
A
D
I
V
A
E
Q
E
K
L
L
W
A
D
T
--
V
I
F
Q
F
P
L
W
W
F
S
M
P
A
I
M
K
G
W
I
D
R
V
Y
A
W
G
F
A
Y
G
V
G
--
E
H
S
DRHWGDRY---
G
E
G
--
T
F
V
G
K
R
A
M
L
I
V
T
A
G
G
W
A
E
H
Y
S
P
R
G
--
I
N
-
G
P
I
D
D
I
L
F
-
P
I
Q
H
G
M
L
F
Y
P
G
F
E
V
L
P
P
---
L
V
F
Y
R
T
D
K
T
D
A
G
Q
F
A
D
Q
C
A
--------------------------------------------
115
HHSearch
80.07
24%
-68
- C2 -
-
4GI5
9
?
B:
[22-232]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
K
V
L
L
I
Y
A
-
H
P
E
----
P
----
R
S
L
N
G
-
A
L
K
N
F
A
I
R
H
L
Q
Q
A
G
H
-
E
V
Q
V
S
D
L
Y
A
M
-----------------------------
R
W
K
A
G
Y
----------------------------
D
ADDSGAPPVGEFWRPT
L
D
S
K
Q
A
F
A
Q
GT
Q
S
A
D
I
V
A
E
Q
E
K
L
L
W
A
D
T
--
V
I
F
Q
F
P
L
W
W
F
S
M
P
A
I
M
K
G
W
I
D
R
V
Y
A
W
G
F
A
Y
G
V
G
--
E
H
S
DRHWGDRY---
G
E
G
--
T
F
V
G
K
R
A
M
L
I
V
T
A
G
G
W
A
E
H
Y
S
P
R
G
--
I
N
-
G
P
I
D
D
I
L
F
-
P
I
Q
H
G
M
L
F
Y
P
G
F
E
V
L
P
P
---
L
V
F
Y
R
T
D
K
T
D
A
G
Q
F
A
D
Q
C
A
--------------------------------------------
1
PsiBlast_PDB
79.83
33%
-85
- C2 -
-
5LVA
2
?
A:
[2-164]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
L
V
L
A
F
-
H
P
N
----
M
----
E
--
Q
S
-
V
V
N
R
A
F
A
D
T
L
K
D
A
-
P
-
G
I
T
L
R
D
L
Y
Q
E
-----------------------------
Y
P
D
E
A
I
----------------------------
D
---------------------------
V
------
E
K
E
Q
K
L
C
E
E
H
D
R
I
V
F
Q
F
P
L
Y
W
Y
S
S
P
P
L
L
K
K
W
L
D
H
V
L
--
L
Y
G
W
A
Y
G
--
T
-------------
N
G
T
--
A
L
R
G
K
E
F
M
V
A
V
S
A
G
A
P
E
E
A
Y
Q
A
G
G
--
S
N
H
Y
A
I
S
E
L
L
R
-
P
-
F
Q
A
T
S
N
F
I
G
T
T
Y
L
P
P
---
Y
V
F
Y
Q
A
G
T
A
G
K
S
E
L
A
E
G
A
T
--------------------------------------------
119
HHSearch
78.26
26%
-41
- C2 -
-
4FGL
4
NQO2_HUMAN
A:
[5-203]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
K
V
L
I
V
Y
A
-
H
Q
E
----
P
----
K
S
F
N
G
-
S
L
K
N
V
A
V
D
E
L
S
R
Q
G
C
-
T
V
T
V
S
D
L
Y
A
M
-----------------------------
N
F
E
P
R
A
TDKDITGTLSNPEVFN
Y
G
V
E
T
H
E
A
Y
K
Q
R
S
---------------------------
L
A
S
D
I
T
D
E
Q
K
K
V
R
E
A
D
L
--
V
I
F
Q
F
P
L
Y
W
F
S
V
P
A
I
L
K
G
W
M
D
R
V
L
C
Q
G
F
A
F
D
I
P
--
G
FY-----------
D
S
G
--
L
L
Q
G
K
L
A
L
L
S
V
T
T
G
G
T
A
E
M
Y
T
K
T
G
--
V
N
-
G
D
S
R
Y
F
L
W
P
L
-
Q
H
G
T
L
H
F
C
G
F
K
V
L
A
P
---
Q
I
S
F
A
P
E
I
A
S
E
E
E
R
-------------------------------------------------
2
PsiBlast_PDB
78.02
26%
-40
- C2 -
-
3F2V
1
?
A:
[2-177]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
K
T
L
I
I
L
A
-
H
P
N
----
I
----
S
--
Q
S
-
T
V
H
K
H
W
S
D
A
V
R
Q
H
T
D
-
R
F
T
V
H
E
L
Y
A
V
-----------------------------
Y
P
Q
G
K
I
----------------------------
D
---------------------------
V
----
A
A
E
Q
K
L
I
E
T
H
D
S
--
L
V
W
Q
F
P
I
Y
W
F
N
C
P
P
L
L
K
Q
W
L
D
E
V
L
T
--
Y
G
W
A
Y
G
--
S
-------------
K
G
K
--
A
L
K
G
R
K
I
A
L
A
V
S
L
G
A
P
A
A
D
Y
R
A
D
G
--
A
V
G
C
S
V
A
E
V
L
R
-
P
-
F
E
L
T
A
K
Y
C
N
A
D
Y
R
P
P
F
T
F
H
T
--------
S
E
A
A
R
Q
E
V
E
R
S
A
R
D
Y
L
A
W
-----------------------------------
118
HHSearch
78.00
25%
-43
- C2 -
-
1QR2
2
NQO2_HUMAN
A:
[2-202]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
K
V
L
I
V
Y
A
-
H
Q
E
----
P
----
K
S
F
N
G
-
S
L
K
N
V
A
V
D
E
L
S
R
Q
G
C
-
T
V
T
V
S
D
L
Y
A
M
-----------------------------
N
F
E
P
R
A
TDKDITGTLSNPEVFN
Y
G
V
E
T
H
E
A
Y
K
Q
R
S
---------------------------
L
A
S
D
I
T
D
E
Q
K
K
V
R
E
A
D
L
--
V
I
F
Q
F
P
L
Y
W
F
S
V
P
A
I
L
K
G
W
M
D
R
V
L
C
Q
G
F
A
F
D
I
P
--
G
FY-----------
D
S
G
--
L
L
Q
G
K
L
A
L
L
S
V
T
T
G
G
T
A
E
M
Y
T
K
T
G
--
V
N
-
G
D
S
R
Y
F
L
W
P
L
-
Q
H
G
T
L
H
F
C
G
F
K
V
L
A
P
---
Q
I
S
F
A
P
E
I
A
S
E
E
E
R
K
G
-----------------------------------------------
127
HHSearch
76.24
27%
-100
- C2 -
-
3HA2
1
?
B:
[1-161]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
T
L
I
I
V
A
-
H
P
E
----
L
AR--
S
N-
T
Q
-
P
F
F
K
A
A
I
E
N
F
S
-----
N
V
T
W
H
P
L
V
A
---------------------------------------------------------------------------------------------
D
F
N
V
E
Q
E
Q
S
L
L
L
Q
N
D
R
--
I
I
L
E
F
P
L
Y
W
Y
S
A
P
A
L
L
K
Q
W
M
D
T
V
M
T
T
K
F
A
T
G
H
------------------
Q
Y
--
A
L
E
G
K
E
L
G
I
V
V
S
T
G
D
N
G
N
A
F
Q
A
G
A
--
A
E
K
F
T
I
S
E
L
M
R
-
P
-
F
E
A
F
A
N
K
T
K
M
M
Y
L
P
I
---
L
A
V
H
Q
F
L
Y
L
E
P
D
A
Q
Q
R
L
L
V
A
Y
Q
-----------------------------------------
122
HHSearch
73.03
23%
-65
- C2 -
-
1GG5
2
NQO1_HUMAN
A:
[2-195]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
R
A
L
I
V
L
A
-
H
S
E
----
R
----
T
S
F
N
Y
-
A
M
K
E
A
A
A
A
A
L
K
K
K
G
W
-
E
V
V
E
S
D
L
Y
A
M
-----------------------------
N
F
N
P
I
I
SRKDITGKLKDPANFQ
Y
P
A
E
S
V
L
A
Y
K
E
G
H
---------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
--
V
I
F
Q
F
P
L
Q
W
F
G
V
P
A
I
L
K
G
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
AM
Y
-------------
D
K
G
--
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
G
--
I
H
-
G
D
M
N
V
I
L
W
-
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
---
Q
L
T
Y
S
I
G
H
T
------------------------------------------------------
103
Fugue
72.87
23%
-34
- C2 -
-
1QR2
2
NQO2_HUMAN
A:
[1-230]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
K
K
V
L
I
V
Y
A
H
Q
E
----
P
----
K
S
F
N
G
-
S
L
K
N
V
A
V
D
E
L
S
R
Q
-
G
C
T
V
T
V
S
D
L
Y
A
M
NFEPRATDKDITGTLSNPEVFN
Y
G
V
E
T
H
E
A
-
Y
K
Q
R
----------------------------
S
---------------------------
L
A
S
D
I
T
D
E
Q
K
K
V
R
E
A
D
L
--
V
I
F
Q
F
P
L
Y
W
F
S
V
P
A
I
L
K
G
W
M
D
R
V
L
C
Q
G
F
A
F
D
I
P
--
G
-------------
F
Y
D
SG
L
L
Q
G
K
L
A
L
L
S
V
T
T
G
G
T
A
E
M
Y
T
K
T
G
--
V
N
G
D
S
R
Y
F
L
W
P
-
L
-
Q
H
G
T
L
H
F
C
G
F
K
V
L
A
P
---
Q
I
S
F
A
P
E
I
A
S
E
E
E
R
K
G
M
V
A
A
W
S
Q
R
L
Q
T
I
W
K
E
E
P
I
P
C
T
A
H
W
H
F
G
Q
-------------------
121
HHSearch
72.66
23%
-75
- C2 -
-
1D4A
2
NQO1_HUMAN
C:
[2-195]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
R
A
L
I
V
L
A
-
H
S
E
----
R
----
T
SF
N
Y
-
A
M
K
E
A
A
A
A
A
L
K
K
K
G
W
-
E
V
V
E
S
D
L
Y
A
M
-----------------------------
N
F
N
P
I
I
SRKDITGKLKDPANFQYPAESVLAYKEG
H
---------------------------
L
S
P
D
I
V
A
E
Q
K
K
L
E
A
A
D
L
--
V
I
F
Q
F
P
L
Q
W
F
G
V
P
A
I
L
K
G
W
F
E
R
V
F
I
G
E
F
A
Y
T
Y
A
AM
Y
-------------
D
K
G
--
P
F
R
S
K
K
A
V
L
S
I
T
T
G
G
S
G
S
M
Y
S
L
Q
G
--
I
H
-
G
D
M
N
V
I
L
W
-
P
I
Q
S
G
I
L
H
F
C
G
F
Q
V
L
E
P
---
Q
L
T
Y
S
I
G
H
T
------------------------------------------------------
123
HHSearch
70.97
20%
-51
- C2 -
-
4S24
4
?
A:
[4-177]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
N
V
L
I
I
N
A
-
M
K
E
F
AHS
K
----
G
A-
L
N
L
T
L
T
N
V
A
A
D
F
L
R
E
S
G
H
-
Q
V
K
I
T
T
V
D
Q
---------------------------------------------------------------------------------------------
G
Y
D
I
E
S
E
I
E
N
Y
L
W
A
D
T
--
I
I
Y
Q
M
P
A
W
W
M
G
E
P
W
I
L
K
K
Y
I
D
E
V
F
T
D
G
H
G
R
L
Y
Q
--
S
DGRTATKGYG---
S
G
G
--
L
I
Q
G
K
T
Y
M
L
S
V
T
W
N
A
P
R
E
A
F
T
D
P
E
QF
F
H
G
V
G
V
D
G
V
Y
L
-
P
-
F
H
K
A
N
Q
F
L
G
M
K
P
L
P
T
---
F
M
C
N
D
V
I
K
Q
------------------------------------------------------
129
HHSearch
70.33
20%
-42
- C2 -
-
3RPE
2
?
B:
[25-198]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
N
V
L
I
I
N
A
-
M
K
E
----
F
AHSK
G
A
L
N
L
-
T
L
T
N
V
A
A
D
F
L
R
E
S
G
H
-
Q
V
K
I
T
T
V
D
Q
---------------------------------------------------------------------------------------------
G
Y
D
I
E
S
E
I
E
N
Y
L
W
A
D
T
--
I
I
Y
Q
M
P
A
W
W
M
G
E
P
W
I
L
K
K
Y
I
D
E
V
F
T
D
G
H
G
R
L
Y
Q
--
S
DGRTRSDATKGYG
S
G
G
--
L
I
Q
G
K
T
Y
M
L
S
V
T
W
N
A
P
R
E
A
F
T
D
P
E
QF
F
H
G
V
G
V
D
G
V
Y
L
-
P
-
F
H
K
A
N
Q
F
L
G
M
K
P
L
P
T
---
F
M
C
N
D
V
I
K
Q
------------------------------------------------------