@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0108: (2017-12-15 )
MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAYIPKNYIVKANGNSVITGTEFLSAISSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQASSLNKQLVKLRAKEAIFQKFEQSLNEKYNRMSNSGEEQEYYGKVEYYLSQLNSENYNNGTQYSKIQDEYTKLNKITAERNQLDADLQTLQNELIQLQQQGDSPSLSDTTSADDKAKLETKILEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLVSELGTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLVPLKQGMSIQQGQTIAEVSGKEKGYYVEAFVLASDISRVSKGAKVDVAITGVNSQKYGTLKGQVRQIDSGTISQETKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
Atome Classification :
(20 SA)
.........10........20........30........40........--50........60........---70........80........90........100.......110----.......120.....----------..130.......140.......150.......160.-----......170.......180.......190---.......200........210.......-220.......230.......240...------....250.......260.......270.........280.......290.......300.......310.......320......-.330-.---........340.......350......----.360-------.........370.......380.......390.......400.......410.......420.......430.......440.......450
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MKLYNKSE
L
R
Y
S
R
I
F
FDKRPP
A
F
A
F
I
L
I
I
S
T
A
I
I
L
S
G
A
L
V
G
A
A
YIPK
N
Y
--
I
V
KANG
N
S
V
I
T
G
T
E
F
L
S
A
IS---SG
K
V
V
T
L
HKSEG
D
M
VNA
G
D
V
I
I
S
LSSGQEGL
Q
A
S
S
L
N
K
Q
L
V
K
L
----
R
A
K
E
A
I
F
Q
K
F
E
Q
S
L
N
----------
E
K
Y
N
RMSNSG
E
E
Q
E
Y
Y
G
K
V
E
Y
Y
L
S
Q
LNSENYNNGTQ-----
Y
S
K
I
Q
D
E
Y
T
K
L
N
K
I
TAERNQL
D
A
D
L
Q
T
L
Q
---
N
E
L
I
Q
L
Q
QQ-GDSPSLSDTTSAD
D
K
A
K
L
-
E
T
K
I
L
E
I
T
T
K
I
E
A
L
KTNITSKNSEI
D
------
S
Q
Q
S
N
I
K
D
M
N
RTYNDP
T
S
Q
A
Y
N
I
Y
A
--
Q
L
V
S
E
LGTARSNNNK
S
I
T
E
L
EANLGVATGQDKA
H
S
I
LAPNE
G
T
L
H
Y
L
V
PLKQGMSIQQ-G
Q
---
T
---
I
A
E
VSGKEK
G
Y
Y
V
E
A
F
V
L
A
S
D
I
S
R
VSK----G
A
---------
K
V
D
V
A
I
TGVNSQKYGTLK
G
Q
V
R
QIDSGTISQETKEG
N
I
S
L
Y
K
V
M
I
E
L
E
T
L
T
LKHGS
E
T
V
V
L
QKDM
P
V
E
V
R
I
V
YD
K
E
T
Y
L
D
W
I
L
E
M
LSFKQ
44
Fugue
86.73
19%
-99
- C4 -
-
4TKO
2
?
B:
[3-349]
------------------
H
R
I
E
Y
A
I
T
--------------------
N
A
V
--
F
V
K
A
D
E
------
L
S
Y
L
S
F
R
V
---
S
G
K
V
I
E
V
Y
K
D
L
G
D
Y
V
K
R
G
E
A
L
A
K
L
D
P
T
Y
Y
E
L
E
K
R
T
L
E
K
K
M
S
A
L
----
L
E
K
K
---
K
A
L
E
I
K
I
Q
----------
K
L
E
K
G
L
H
I
S
L
S
A
K
K
L
----------------------------
K
V
E
S
L
K
K
K
R
E
A
L
R
E
K
L
L
Q
V
E
E
K
I
K
L
V
K
---
L
D
W
E
R
Y
K
S
L
-
F
Q
K
----
G
L
I
P
R
R
K
F
E
E
V
-
D
T
N
L
K
V
L
L
H
E
R
E
Y
L
E
K
S
I
Q
E
I
N
T
E
I
K
------
R
A
K
K
G
I
E
N
A
R
N
E
F
K
T
I
E
E
L
K
K
E
L
--------------
S
S
L
E
E
E
I
K
S
L
K
E
R
I
K
T
A
E
Q
K
I
K
D
T
V
L
I
A
P
F
D
G
V
V
A
K
R
-
F
I
S
R
G
D
V
V
R
A
-
G
Q
---
P
---
A
F
A
L
V
N
P
E
S
-
F
Y
V
E
V
L
L
E
E
T
K
L
K
G
V
K
V
----
G
N
---------
K
A
Y
V
R
L
D
A
Y
P
D
I
L
---
F
E
G
V
V
E
E
I
S
P
-----------
V
Q
R
I
P
V
K
I
K
I
T
K
G
D
L
S
L
------
L
R
V
G
M
G
G
E
V
E
I
R
R
T
----------------
21
HHSearch
78.69
19%
29
- C4 -
-
4TKO
2
?
B:
[3-349]
--------------------------------------------
H
R
I
E
Y
--
A
I
T
N
A
V
F
V
K
A
D
E
L
S
Y
L
S
F
R
V
---
S
G
K
V
I
E
V
Y
K
D
L
G
D
Y
V
K
R
G
E
A
L
A
K
L
D
P
T
Y
Y
E
L
E
K
R
T
L
E
K
K
M
S
A
L
----
L
E
K
K
K
A
L
E
I
K
I
Q
K
L
E
----------
K
G
L
H
I
S
-------------------
L
S
A
K
K
L
K
V
E
S
L
-----
K
K
K
R
E
A
L
R
E
-------
K
L
L
Q
V
E
E
K
I
K
L
V
K
LDW
E
R
Y
K
S
L
F
Q
K
-
G
L
I
P
R
----------------------
R
K
F
E
E
V
D
T
N
L
K
V
L
L
H
E
R
E
------
Y
L
E
K
S
I
Q
E
I
N
T
E
I
K
R
A
K
K
G
I
E
N
A
R
N
EF
K
T
I
E
E
L
K
K
E
L
S
S
L
E
E
E
I
K
S
L
K
E
R
I
K
T
A
E
Q
K
I
K
D
T
V
L
I
A
P
F
D
G
V
V
A
K
R
-
F
I
S
R
G
D
V
V
R
A
-
G
Q
---
P
---
A
F
A
L
V
N
P
-
E
S
F
Y
V
E
V
L
L
E
E
T
K
L
K
G
V
K
V
----
G
N
---------
K
A
Y
V
R
L
D
A
Y
P
---
D
I
L
F
E
G
V
V
E
E
I
S
P
-----------
V
Q
R
I
P
V
K
I
K
I
T
K
G
------
D
L
S
L
L
R
V
G
M
G
G
E
V
E
I
R
R
T
----------------
23
HHSearch
72.71
19%
-6
* C4 *
-
3FPP
-
MACA_ECOLI
B:
[43-302]
-------------------------------------------
P
G
D
L
Q
Q
--
S
V
L
A
T
G
K
L
D
A
L
R
K
V
D
V
G
A
Q
V
---
S
G
Q
L
K
T
L
S
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
E
L
----
R
A
Q
R
Q
Q
A
E
A
E
L
K
-----------------------------------------------------------
L
A
-------
R
V
T
-------
Y
-------
S
R
Q
Q
R
L
A
Q
T
-
Q
A
V
S
Q
----------------------
Q
D
L
D
N
A
A
T
E
M
A
V
--------------------------------------------
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
-
T
T
L
Q
G
Q
T
V
I
A
-
A
Q
Q
A
P
N
---
I
L
T
L
A
D
M
-
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
A
W
F
T
V
L
G
D
Q
---
L
T
R
Y
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
N
----
D
A
I
F
Y
Y
A
R
F
E
V
P
N
P
-------
N
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
---------------
22
HHSearch
72.07
19%
-2
- C4 -
-
5NIK
-
?
G:
[48-302]
------------------------------------------------
Q
--
S
V
L
A
T
G
K
L
D
A
L
R
K
V
D
V
G
A
Q
V
---
S
G
Q
L
K
T
L
S
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
E
L
----
R
A
Q
R
Q
Q
A
E
A
E
L
-----------------------------------------------------------
K
L
-------
A
R
V
T
-------
Y
-------
S
R
Q
Q
R
L
A
Q
T
-
Q
A
V
S
Q
----------------------
Q
D
L
D
N
A
A
T
E
M
A
V
--------------------------------------------
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
-
T
T
L
Q
G
Q
T
V
I
A
-
A
Q
QAP
N
---
I
L
T
L
A
D
M
-
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
A
W
F
T
V
L
G
D
Q
---
L
T
R
Y
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
N
----
D
A
I
F
Y
Y
A
R
F
E
V
P
N
P
-------
N
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
---------------
27
HHSearch
67.10
20%
0
- C- -
-
4DK1
-
MEXA_PSEAE
A:
[39-294]
-------------------------------------------
R
G
N
I
E
K
--
N
V
V
A
T
G
S
I
E
S
I
N
T
V
D
V
G
A
Q
V
---
S
G
K
I
T
K
L
Y
V
K
L
G
Q
Q
V
K
K
G
D
L
L
A
E
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
----
Q
E
Q
A
Q
R
----------------------------------------------------------------------------------------------
Y
K
L
L
V
A
D
-
Q
A
V
S
-----------------------------
K
Q
---------------------------------------------------
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
I
T
S
P
I
D
G
T
V
I
S
T
-
P
V
S
E
G
Q
T
V
N
S
-
N
Q
---
T
TPT
I
I
K
V
A
D
L
-
S
K
M
R
I
K
P
E
I
S
E
G
D
I
T
K
V
K
A
----
G
Q
---------
D
V
T
F
T
I
L
S
D
N
---
K
T
V
Y
H
A
K
I
D
S
V
D
P
A
T
T
T
I
S
D
---
S
A
V
Y
Y
Y
A
N
I
I
V
E
N
P
-------
E
H
V
L
R
I
G
M
T
T
E
N
N
I
K
I
A
D
---------------
33
HHSearch
53.29
16%
-167
- C4 -
-
3T53
-
CUSB_ECOLI
C:
[127-244]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
T
R
F
T
L
K
A
P
I
D
G
V
I
T
A
F
-
D
L
R
A
G
M
N
I
A
K
-
D
N
---
V
---
V
A
K
I
Q
G
M
-
D
P
V
W
V
T
A
A
I
P
E
S
I
A
W
L
V
K
D
----
A
S
---------
Q
F
T
L
T
V
P
A
R
P
---
D
K
T
L
T
I
R
K
W
T
L
L
P
G
V
D
A
A
------
T
R
T
L
Q
L
R
L
E
V
D
N
A
-------
D
E
A
L
K
P
G
M
N
A
W
L
Q
L
N
T
A
S
---------------
36
HHSearch
53.12
16%
-145
- C4 -
-
4KKS
-
?
A:
[94-209]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
P
V
R
A
P
I
S
G
Y
I
L
N
I
-
T
K
K
I
G
E
T
V
N
P
-
Q
S
---
N
---
I
A
V
V
G
R
I
-
D
T
K
Q
I
L
T
Y
V
S
E
K
Y
I
S
N
I
K
V
----
G
N
---------
D
A
I
I
E
V
G
A
Y
S
---
N
E
K
F
K
A
K
V
S
E
I
S
P
I
L
D
S
K
------
S
R
T
I
E
V
Y
L
T
P
I
G
S
------
N
L
D
K
L
I
I
G
M
F
S
K
I
K
L
I
T
K
R
---------------
24
HHSearch
52.74
16%
-27
- C4 -
-
2F1M
-
ACRA_ECOLI
D:
[54-297]
----------------------------------------------------
T
E
L
P
G
R
T
S
A
Y
R
I
A
E
V
R
P
Q
V
---
S
G
I
I
L
K
R
N
F
K
E
G
S
D
I
E
A
G
V
S
L
Y
Q
I
D
P
A
T
Y
Q
A
T
Y
D
S
A
K
G
D
L
A
K
A
----
Q
A
A
A
N
I
A
Q
L
T
-----------------------------------------------------------
V
----------------------------
N
R
Y
Q
K
L
L
G
T
-
Q
Y
I
S
---
K
-------------------
Q
E
Y
D
Q
A
L
---------------------------------------------------
A
D
A
Q
Q
A
N
A
A
V
T
A
A
K
A
A
V
E
T
A
R
I
N
L
A
Y
T
K
V
T
S
P
I
S
G
R
I
G
K
S
-
N
V
T
E
G
A
L
V
Q
N
-
G
Q
AT-
A
---
L
A
T
V
Q
Q
L
-
D
P
I
Y
V
D
V
T
Q
S
--------------
G
---------
K
A
K
V
S
L
I
T
S
D
G
I
-
K
F
P
Q
D
G
T
L
E
F
S
D
V
T
V
D
Q
T
------
T
G
S
I
T
L
R
A
I
F
P
N
P
-------
D
H
T
M
M
P
G
M
F
V
R
A
R
L
-------------------
1
PsiBlast_PDB
52.38
23%
138
- C3 -
-
4TKO
1
?
B:
[3-240]
-----------------------------------------------
H
R
--
I
E
Y
A
I
T
N
A
V
F
V
K
A
D
E
L
S
Y
L
S
FRV
S
G
K
V
I
E
V
Y
K
D
L
G
D
Y
V
K
R
G
E
A
L
A
K
L
D
P
T
Y
Y
E
L
E
K
R
T
L
E
K
K
M
S
A
L
LEKK
K
A
L
E
I
K
I
Q
K
L
E
K
G
L
H
ISLSAKKLKV
E
S
L
K
K
K
R
E
A
L
R
E
K
L
L
Q
V
E
E
K
I
K
L
V
K
L
D
W
E
R
Y
K
S
L
F
Q
KGLIP
R
R
K
F
E
E
V
D
T
N
L
K
V
L
L
H
E
R
E
Y
L
E
K
S
I
Q
E
I
N
---
T
E
-
I
K
R
A
K
K
-
G
I
E
N
A
R
N
E
F
K
T
------------------
I
E
E
L
K
K
E
L
S
S
L
E
E
E
I
K
------
S
L
K
E
R
I
K
T
A
E
Q
K
I
K
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
52.15
13%
-28
- C4 -
-
5C22
-
HLYDC_ECOLX
A:
[3-268]
---------------------------------------------------------------
S
K
E
I
K
P
I
E
---
N
S
I
V
K
E
I
I
V
K
E
G
E
S
V
R
K
G
D
V
L
L
K
L
T
A
L
G
A
E
A
D
T
L
K
T
Q
S
S
L
L
Q
T
----
R
L
E
Q
T
R
Y
Q
I
L
S
R
S
I
E
----------
L
N
K
L
P
E
L
K
L
P
D
E
P
Y
F
Q
----------
N
V
S
E
E
E
V
L
R
L
-----
T
S
L
I
K
E
Q
F
S
T
W
Q
N
Q
K
Y
Q
K
E
L
N
L
D
K
K
R
A
E
R
---
L
T
I
L
A
R
I
N
R
-
Y
E
N
L
S
R
V
E
K
S
R
L
D
D
F
R
S
L
-
L
H
K
Q
A
I
A
K
H
A
V
L
E
Q
E
N
K
Y
V
E
A
A
N
E
L
R
------
V
Y
K
S
Q
L
E
Q
I
E
S
E
I
L
S
A
K
E
E
Y
Q
L
V
T
R
--
L
F
K
N
E
I
L
D
K
L
R
Q
T
T
D
N
I
E
L
L
T
L
E
L
E
K
N
E
E
R
Q
Q
A
S
V
I
R
A
P
V
S
G
K
V
Q
Q
L
K
V
H
T
E
G
G
V
V
T
T
-
A
E
---
T
---
L
M
V
I
V
P
------------------------------------------------------------------------------------------------------------------------------
49
Fugue
50.05
27%
-23
- C4 -
-
5J0K
-
?
A:
[6-79]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
R
T
E
I
I
R
E
L
E
R
S
L
R
E
Q
E
E
L
A
K
R
L
K
E
L
L
---
R
E
L
E
R
L
Q
R
E
-
G
S
S
--------
D
E
D
V
R
E
L
-
L
R
E
I
K
E
L
V
E
E
I
E
K
L
A
R
E
Q
K
Y
L
V
E
E
L
K
------
R
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
48.78
15%
-8
- C4 -
-
2V4D
-
MEXA_PSEAE
G:
[22-263]
-------------------------------------------
A
Q
T
V
T
L
--
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
---
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
----
Q
E
Q
A
Q
R
Y
----------------------------------------------------------------------------------------------
K
L
L
V
A
D
-
Q
A
V
S
-----------------------------
K
Q
Q
---------------------------------------------------
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
-
A
V
T
E
G
A
L
V
T
N
-
G
Q
---
A
NA-
M
A
T
V
Q
Q
L
-
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
ELAS
G
Q
LERAGDNAA
K
V
S
L
K
L
E
D
G
S
---
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
------
T
G
S
V
T
I
R
A
V
F
P
N
P
-------
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
---------------
29
HHSearch
48.30
15%
-5
- C4 -
-
1VF7
-
MEXA_PSEAE
J:
[26-260]
-----------------------------------------------
T
L
--
N
T
E
L
P
G
R
T
N
A
F
R
I
A
E
V
R
P
Q
V
---
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
----
Q
E
Q
A
Q
R
----------------------------------------------------------------------------------------------
Y
K
L
L
V
A
D
-
Q
A
V
S
-----------------------------
K
Q
Q
---------------------------------------------------
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
-
A
V
T
E
G
A
L
V
T
N
-
G
Q
---
A
NA-
M
A
T
V
Q
Q
L
-
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
ELAS
G
Q
LERAGDNAA
K
V
S
L
K
L
E
D
G
S
---
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
------
T
G
S
V
T
I
R
A
V
F
P
N
P
-------
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
------------------
12
PsiBlast_PDB
44.69
27%
87
- C- -
-
3S5I
-
?
A:
[852-981]
--------------------------------------------------------------------------------------------------------------------------------------
L
K
----------
R
K
I
N
G
M
K
T
T
F
S
E
K
G
Y
A
I
L
M
K
Y
V
K
A
H
L
N
S
K
H
Y
A
H
N
I
I
-----
Y
G
-----
Y
E
N
Y
L
K
L
Q
E
Q
L
E
L
A
E
N
D
F
K
T
L
E
---
N
I
L
V
R
I
R
N
K
I
F
N
K
K
N
L
M
V
S
V
T
S
D
Y
G
A
----
L
K
H
L
F
V
N
S
N
-
E
S
L
K
-
N
L
V
S
Y
F
E
E
N
D
------
K
Y
---
I
N
D
M
Q
N
K
V
N
D
P
T
V
M
G
W
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
44.20
11%
76
- C4 -
-
3FPP
-
MACA_ECOLI
A:
[43-308]
---------------------------------------------
P
G
D
L
Q
Q
S
V
L
A
T
G
K
L
D
A
L
R
K
V
D
V
G
A
Q
V
---
S
G
Q
L
K
T
L
S
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
E
L
----
R
A
Q
R
Q
Q
A
E
A
E
L
K
L
A
R
----------
V
T
Y
S
R
Q
Q
R
L
A
Q
T
Q
A
V
-
S
Q
Q
D
L
D
N
A
A
T
E
M
A
V
K
Q
A
Q
I
G
-----
T
I
D
A
Q
I
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
T
R
I
V
A
P
M
---
A
G
E
V
T
Q
I
T
T
-
L
Q
G
Q
T
V
I
A
A
Q
Q
A
P
N
I
L
T
L
A
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
G
Q
K
A
W
F
T
V
LGD
Q
L
T
R
Y
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
N
D
A
I
F
Y
--
Y
A
R
F
E
V
P
N
P
N
G
L
L
R
L
D
M
-
T
A
Q
V
H
I
Q
L
T
D
V
K
N
V
L
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
43.38
16%
-110
- C- -
-
4KKU
-
?
A:
[115-230]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
P
V
R
A
P
I
S
G
Y
I
L
N
I
-
T
K
K
I
G
E
T
V
N
P
-
Q
S
---
N
---
I
A
V
V
G
R
I
-
D
T
K
Q
I
L
T
Y
V
S
E
K
Y
I
S
N
I
K
V
----
G
N
---------
D
A
I
I
E
V
G
A
Y
S
---
N
E
K
F
K
A
K
V
S
E
I
S
P
I
L
D
S
K
------
S
R
T
I
E
V
Y
L
T
P
I
G
S
------
N
L
D
K
L
I
I
G
-
F
S
K
I
K
L
I
T
K
R
---------------
13
PsiBlast_PDB
42.08
27%
93
* C2 *
-
3S5M
-
?
A:
[852-981]
--------------------------------------------------------------------------------------------------------------------------------------
L
K
----------
R
K
I
N
G
M
K
T
T
F
S
E
K
G
Y
A
I
L
M
K
Y
V
K
A
H
L
N
S
K
H
Y
A
H
N
I
I
-----
Y
G
-----
Y
E
N
Y
L
K
L
Q
E
Q
L
E
L
A
E
N
D
F
K
T
L
E
---
N
I
L
V
R
I
R
N
K
I
F
N
K
K
N
L
M
V
S
V
T
S
D
Y
G
A
----
L
K
H
L
F
V
N
S
N
-
E
S
L
K
-
N
L
V
S
Y
F
E
E
N
D
------
K
Y
---
I
N
D
M
Q
N
K
V
N
D
P
T
V
M
G
W
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
42.07
16%
27
- C4 -
-
3LNN
-
?
A:
[169-284]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
I
L
A
V
R
S
P
I
N
G
R
V
V
D
L
-
N
A
A
T
G
A
Y
W
N
D
T
T
A
---
S
---
L
M
T
V
A
D
L
-
S
H
V
F
V
T
A
N
A
Q
E
K
D
L
G
H
V
Y
V
----
G
Q
---------
S
A
T
V
K
F
D
A
Y
D
----
D
P
Q
P
G
K
V
R
Y
V
G
Q
I
L
D
A
D
------
T
R
T
T
K
V
R
M
V
F
D
N
P
-------
D
G
R
L
R
P
G
M
F
A
Q
A
T
F
L
S
Q
P
---------------
25
HHSearch
41.24
19%
209
- C4 -
-
4DK0
-
?
A:
[39-322]
-------------------------------------------
R
G
N
I
E
K
--
N
V
V
A
T
G
S
I
E
S
I
N
T
V
D
V
G
A
Q
V
---
S
G
K
I
T
K
L
Y
V
K
L
G
Q
Q
V
K
K
G
D
L
L
A
E
I
D
S
T
T
Q
I
N
T
L
N
T
R
K
A
A
L
A
S
Y
----
Q
A
Q
L
V
A
R
K
T
A
-----------------------------------------------------------
Y
D
V
A
L
S
N
--------------
Y
-------
Q
R
L
S
K
L
Y
G
Q
-
K
A
T
S
L
----------------------
D
T
L
N
T
A
K
A
T
-------
L
N
-------------------------------------
N
A
K
A
E
M
D
V
V
Q
E
N
I
K
Q
A
E
I
E
V
N
T
A
E
T
N
L
G
Y
T
K
I
T
S
P
I
D
G
T
V
I
S
T
-
P
V
S
E
G
Q
T
V
N
S
-
N
Q
---
T
T
P
T
I
I
K
V
A
D
L
-
S
K
M
R
I
K
P
E
I
S
E
G
D
I
T
K
V
K
A
----
G
Q
---------
D
V
T
F
T
I
L
S
D
N
---
K
T
V
Y
H
A
K
I
D
S
V
D
P
A
T
T
T
I
S
D
---
S
A
V
Y
Y
Y
A
N
I
I
V
E
N
P
-------
E
H
V
L
R
I
G
M
T
T
E
N
N
I
K
I
A
D
---------------
34
HHSearch
41.05
19%
-180
- C4 -
-
5C22
-
HLYDC_ECOLX
B:
[207-268]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
D
K
L
R
Q
T
T
D
N
I
E
L
L
T
L
E
L
E
K
N
E
E
R
Q
Q
A
S
V
I
R
A
P
V
S
G
K
V
Q
Q
L
K
V
H
T
E
G
G
V
V
T
T
-
A
E
---
T
---
L
M
V
I
V
P
------------------------------------------------------------------------------------------------------------------------------