@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKE9: (2017-10-26 )
MKKPVPKIYRTTNWSSYNQALIKRGNISIWFDPKTQWYAQPQGKHGRNQTYSDAAIQCCLMIKSLFRLSLRMVTGFAQSLIKLCGLNWTAPDYSTLCRRQKRIDIAISYQQSRDGLHLLVDSTGLKFLGEGEWKRKKHQPAYRRQWRKLHIGIDAKTLQIRAVQLTTNNVSDSQVLGDLLDQIPLDERIDSVYTDGAYDTKHCRQVILDRDAHAVIPPRKNAKPWKDKKLRSLARNELLKTVKRLGRSLWKKWSGYHRRSLVETKMHCIK
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.....------....----10-....---.....20----.------...--------.------.---...30........40..---......--------50--------...-------......---60---------.---------------......------..70.....---------------------.-----------..------80...-.----------------------.-.--..90.....-----------.----..100--------..--..--..----.110.-------..-----------..--..120....---.-----.-.130--.---...-.-....140---..-.......150.-----------------..--.-----..--.160.......170-.....-...180..-.-....190.......200------.....-..-.210....--...220-.-..---...--------.-.-------------------230.-------------....---------...240----........250..------------....-..260.......270---------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKPV------PK
I
Y
----R--TTNW---S
S
Y
N
Q
A
-----
L
------
I
KR--------G------
N
---
I
S
I
W
FDPKT
Q
W
Y
AQPQG---KHGRNQ--------T---------
Y
S
D
-------
A
A
I
Q
C
C
---
L
----------
M
---------------
I
K
S
L
F
R
------
L
S
L
R
M
V
T
G
F
---------------------
A
-----------
Q
S
------
L
I
K
L
C-G----------------------L-N--WTAP
D
Y
S
T
L
-----------
C
----
R
RQ
K
R
--------
I
D
--
I
A
--
I
S
----
Y
QQSR-------D
G
-----------
L
H
--
L
L
VDSTG
L
K
---
F
-----L-GE----G---EWK-R-KKHQ
P
-----
A
Y
-
R
R
Q
W
R
K
L
H
I
G
I
-----------------
D
A
--
K
-----
T
L
--
Q
I
R
A
V
Q
L
TTNNV
S
--
D
S
Q
V
L
-
G
D
L
L
D
QIP-
L
-
D
E
R
I
D
S
V
YTDGAY
D
T
K
-------
H
C
R
Q
V
-
I
L-DRDAHAVI--PPRKN--A-KP---W
K
D
--------
K
-
K
-------------------
L
R
-
S
-------------
L
A
R
N
---------
E
L
L
K
T
-----
V
K
R
L
G
R
S
L
W
-
K
KW------------SGY
H
-
R
R
S
L
V
E
T
K
M
HCIK-----------------------------------------------------------------------
32
Fugue
58.66
18%
7
- C1 -
-
1YT3
-
RND_ECOLI
A:
[1-375]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
N
Y
Q
M
I
TT
D
D
A
L
A
S
L
C
E
A
V
R
A
F
------
P
A
I
A
----
L
--
D
T
E
F
---
V
R
T
R
T
Y
-----
Y
------
P
Q
L
--------
G
------
L
---
I
Q
L
-
F
D
G
E
H
L
A
L
I
D
P
L
G
ITD
W
S
P
L
K
A
--------
I
---------
L
R
D
-------
P
S
I
T
K
F
---
L
H
AG
S
E
D
L
E
--
V
---------------
F
L
N
V
F
G
ELPQP
L
I
D
T
Q
I
L
A
A
F
---------------------
C
GRPMSWG
F
---
A
S
------
M
V
E
E
Y
-
S
G
V
T
L
D
KSESRTDWLARPLT
E
R
Q
C
-
E
--
Y
A
A
A
D
V
W
Y
L
-----------
L
----
P
I
T
A
K
--------
L
M
--
V
E
--
T
E
A
S
GW
L
P
A
A
L
-------
D
E
-----------
C
R
--
L
M
Q
M
R
R
Q
E
V
---
V
-----
A
-
P
E
----
D
---
A
W
R
-
D
-
I
T
N
A
W
-----
Q
L
R
T
R
Q
L
A
C
L
Q
L
L
A
-----------------
D
W
--
R
-----
L
R
--
K
A
R
E
R
D
L
A
V
N
F
V
V
--
R
E
E
H
L
-
W
S
V
A
R
Y
M
P
-
G
S
L
G
E
L
D
S
L
G
L
S
G
S
E
I
R
F
-------
H
G
K
T
L
-
L
A
-
L
V
E
K
A
Q
T
L
--
P
E
D
A
L
--
P
-
Q
P
MLN
L
M
D
MPG
Y
R
K
A
F
K
-
A
-------------------
I
K
-
S
-------------
L
I
T
D
V
S
E
T
H
KISA
E
L
L
A
S
-----
R
R
Q
I
N
Q
L
L
N
-
W
H
W
KLKPQNNLPELI
S
G
W
R
-
G
E
L
M
A
E
A
L
H
N
L
L
Q
EYPQ-------------------------------------------------------------------
38
Fugue
57.99
15%
23
- C4 -
-
4IIK
3
SIDD_LEGPH
A:
[1-314]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
S
I
I
------
T
Q
I
C
NGVL
H
--
G
Q
S
Y
---
Q
S
G
S
N
D
-----
L
------
D
K
---------
G
------
N
---
S
E
I
F
A
S
S
L
-
F
V
H
L
N
E
Q
G
---
K
E
I
K
D
S
D
D
K
I
V
I
G
Y
T
---------
K
D
G
-------
M
A
F
Q
I
V
---
V
D
G
FYGCE
R
Q
A
V
---------------
F
S
F
I
D
N
------
Y
V
L
P
L
I
D
N
F
---------------------
S
-----------
L
D
------
L
T
R
Y
P
D
S
----------------------
K
-
K
--
V
T
E
S
L
I
H
T
I
-----------
Y
----
S
L
R
S
K
HAPLA
E
F
T
M
S
--
L
C
--
V
T
----
Y
Q
K
D
E
-------
Q
L
-----------
F
C
A
G
F
G
I
G
D
T
G
I
A
---
I
-----
K
R
N
E
----
G
---
T
------
I
E
Q
L
-----
V
C
-
H
T
E
V
D
G
F
K
D
A
F
-----------------
D
N
--
Y
-----
S
S
--
A
N
I
D
L
V
I
E
R
N
S
V
F
--
N
T
K
V
M
P
G
D
E
L
V
G
Y
T
Y
V
-
P
P
M
L
E
M
T
E
K
E
F
E
V
E
K
R
-------
I
V
R
H
L
-
N
L
-
D
P
G
N
F
D
D
K
--
D
P
L
F
S
Q
L
L
-
Q
V
---
V
K
S
--------
K
-
Q
-------------------
K
Q
-
L
-------------
V
E
Q
A
---------
K
E
T
G
Q
-----
I
Q
R
F
G
D
D
F
T
V
G
R
L
------------
V
I
P
D
-
Q
L
L
I
N
Q
L
R
I
H
A
L
S
-----------------------------------------------------------------------
37
Fugue
56.44
17%
14
- C3 -
-
4NWV
-
?
A:
[30-384]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVAPVAKANALRT
T
S
S
N
S
I
L
L
K
G
C
------
D
R
I
V
----
T
--
V
V
D
A
---
S
T
Y
D
A
G
--------------
S
--------
A
------
I
---
V
S
I
P
I
T
P
D
I
A
Y
R
L
G
S
T
A
---
R
T
F
Q
R
I
--------
K
---------
Y
R
S
-------
L
K
F
R
V
N
---
A
----------
Q
---------------
C
A
T
--
T
------
T
A
G
G
Y
V
A
G
F
---------------------
V
KDAADVLPTGT
A
S
------
I
P
Y
L
M
-
S
----------------------
N
-
T
G
S
F
T
Q
P
W
W
K
S
T
-----------
V
----
H
N
V
K
I
--------
P
Q
--
K
L
--
F
Y
----
T
E
A
P
T
-------
R
G
ADA
V
R
E
Y
C
P
G
Q
F
H
--
V
L
V
D
S
K
P
S
Q
I
C
P
V
-----
T
-
V
D
----
L
---
E
W
V
-
V
-
E
L
H
D
A
-----
T
F
-
R
K
E
S
D
Q
T
A
I
S
A
-----------------
I
V
AD
H
-----
T
L
--
N
V
Y
G
L
P
A
T
S
N
R
V
G
--
H
I
L
I
S
-
P
I
G
Q
T
P
K
D
-
L
-
T
P
T
R
F
A
T
F
F
G
F
L
P
D
D
K
-------
F
C
--
V
-
R
I
-
P
T
P
V
D
V
V
L
--
T
G
D
N
V
--
Y
-
Q
S
---
V
E
A
--------
T
-
H
-------------------
I
R
-
A
Y
L
V
N
GGL
G
I
D
F
H
L
A
A
Y
N
---------
D
T
T
H
T
-----
I
Q
P
I
I
P
T
L
W
-
N
V
Y
D
V----------
T
G
A
V
-
T
A
P
F
T
S
A
I
Y
D
N
H
V
W
T
HK
D
K
F
V
P
V
S
FQDEPIP
G
T
V
F
D
Y
L
Y
PRS------------------------------------------
36
Fugue
52.55
21%
24
- C7 -
-
5GNG
-
Y1552_HAEIN
A:
[1-214]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
T
K
F
Y
D
YQGE
H
L
I
L
----
Y
--
F
A
G
W
---
G
T
P
P
D
A
VNH
L
I
L
------
P
E
N
--------
H
------
D
---
L
L
I
C
Y
D
------
Y
Q
D
L
N
---
L
D
F
D
L
S
--------
A
---------
Y
R
H
---------
I
R
L
V
---
A
----------
W
---------------
S
M
G
V
W
-------
V
A
E
R
V
L
Q
G
I
----------------------------------
R
------
L
K
S
A
T
-
A
----------------------
V
-
N
--
G
T
G
L
P
C
D
D
-------------------------------
S
--
F
G
--
I
P
----
Y
A
I
F
K
-------
G
T
-----------
L
E
--
N
L
T
E
N
T
R
L
K
---
F
-----
E
-
R
R
----
I
C
GD
K
A
S
-
F
-
E
R
Y
Q
L
-----
F
P
-
A
R
P
F
D
E
I
H
Q
E
L
-----------------
T
A
--
L
-----
F
A
--
M
I
Q
Q
----------------------------
D
K
R
I
D
L
I
----------------
H
W
A
N
A
-
W
V
S
S
R
D
K
--
I
F
--
T
P
A
N
Q
--
H
-
Q
Y
---
W
A
L
--------
R
-
C
-------------------
A
V
-
Q
-------------
E
I
E
G
---------
E
H
Y
-
V
-----
F
S
R
-----
F
-
T
H
W
------------
S
A
L
W
-
D
-----------------------------------------------------------------------------------
31
Fugue
48.80
20%
29
- C4 -
-
4X0Q
6
DPOLQ_HUMAN
A:
[6-772]
S
L
S
I
I
DVASDQ
N
L
F
Q
T
F
I
K
E
W
R
C
KK
R
F
S
I
S
L
A
C
E
K
I
RDDTLVV
G
L
A
V
C
WGGR
D
A
Y
Y
F
S
LL
D
P
S
L
T
LK
D
R
M
W
Y
L
Q
S
C
L
RKESD
K
E
C
S
V
V
I
YDF
I
Q
S
Y
K
I
L
L
LSCGISLE
Q
S
Y
E
D
P
K
V
A
C
W
L
L
DPDSQEPT
L
H
S
I
V
T
S
FLPHELPLLEGMETSQGIQSLGLNAGSEHSGR
Y
R
A
S
V
E
S
I
L
I
F
N
S
M
N
Q
L
N
S
L
L
Q
K
E
NLQDVFRKV
E
M
P
S
Q
Y
C
L
A
L
L
E
L
N
G
I
G
F
S
T
A
E
C
E
S
Q
K
H
I
M
Q
A
K
L
D
A
I
E
T
Q
A
Y
Q
LAGHSFSFTS
S
D
D
I
A
E
VLFLE
L
K
L
P
PQFSTS
K
D
V
L
N
K
L
K
A
L
H
------
P
L
P
G
----
L
--
I
L
E
W
---
R
R
I
T
N
A
-----
I
T
KV
V
F
P
L
Q
R
--------
E
------
K
---
C
L
N
P
F
L
G
M
E
R
I
Y
P
V
S
Q
S
---
H
T
A
T
G
R
I
-------
T
---------
F
T
E
-------
P
N
I
Q
N
V
P
R
D
F
----------
E
---------------
I
K
M
G
M
P
------
F
S
I
S
M
-------------------------
R
-----------
H
A
------
F
V
P
F
P
-
G
----------------------
G
-
S
--
I
L
A
A
D
Y
S
----------------------
Q
--------
L
E
--
L
R
--
I
L
----
A
H
L
S
H
-------
D
R
-----------
R
L
--
I
Q
V
L
N
T
G
A
D
---
V
-----
F
-
R
S
----
I
---
A
A
E
-
W
-
K
M
I
E
P
ESVG
D
D
L
-
R
Q
Q
A
K
Q
I
C
Y
G
I
I
Y
GM-------------
G
A
--
K
-----
S
L
--
G
E
Q
M
------
G
I
K
--
E
N
D
A
A
-
C
Y
I
D
S
F
K
S
-
R
-
Y
T
G
I
N
Q
F
M
T
E
T
V
K
N
C
K
-------
R
D
G
F
V
-
Q
T
-
I
L
G
R
R
R
Y
L
--
P
G
I
K
D
--
N
-
N
P
---
Y
R
K
--------
A
-
H
-------------------
A
E
-
R
-------------
Q
A
I
N
---------
T
I
V
Q
G
S
A
A
D
I
V
K
I
A
T
V
N
I
Q
-
K
Q
L
------------
E
T
F
H
-
S
----
T
F
K
S
H
G
H
R
E
G
M
L
Q
S
DC
P
I
R
G
G
F
F
I
LQLHD
E
L
L
Y
E
V
A
EED
V
V
Q
V
A
Q
I
V
K
N
E
M
E
S
AVKLS
V
K
L
K
V
K
V
K
I
G
A
S
W
G
E
L
K
D
F
D
V
33
Fugue
46.00
19%
-13
* C7 *
-
5T6O
-
PHAC_CUPNH
A:
[1-389]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAFEVGRNVAVTEGAVVFENEY
F
Q
L
L
Q
Y
K
P
LTDKVHA
R
P
L
L
M
V
P
P
C
------
I
N
K
Y
----
Y
--
I
L
D
L
QPE
S
S
L
V
R
H
-----
V
------
V
E
Q
--------
G
------
H
T
V
F
L
V
S
W
R
N
P
D
A
S
M
A
G
S
T
--------
W
D
D
--------
Y
---------
I
E
H
-------
A
A
I
R
A
I
---
E
----------
V
---------------
A
R
D
I
S
G
------
Q
D
K
I
N
V
L
G
F
A
V
G
G
T
I
V
S
T
A
L
A
V
L
A
A
R
GEHP
A
-----------
A
S
------
V
T
L
L
T
-
T
----------------------
L
L
D
--
F
A
D
T
G
I
L
D
V
FVDEGHVQGAP
C
----
A
L
L
R
G
--------
L
E
--
L
A
N
T
F
S
----
F
L
R
P
N
-------
D
L
-----------
V
W
--
N
Y
V
V
D
N
Y
L
K
---
G
NTPVP
F
-
D
L
----
L
---
F
W
N
-
G
D
A
T
N
L
P
-----
G
P
-
W
Y
C
W
Y
L
R
H
T
Y
L
-----------------
Q
N
--
E
LKVPG
K
L
--
T
V
C
G
V
P
V
D
L
A
S
I
D
V
-
P
T
Y
I
Y
-
G
S
R
E
D
H
I
V
-----
P
W
T
A
A
Y
A
S
T
A
L
L
A
N
-------
K
L
R
F
V
-
L
G
-
A
S
G
H
I
A
G
V
I
N
P
P
A
K
N
--
K
R
S
H
---
W
T
N
--------
D
-
A
-------------------
L
P
-
E
-------------
S
P
Q
Q
---------
W
L
A
G
A
-----
I
E
H
H
G
-
S
W
W
-
P
D
W
------------
T
A
W
L
-
A
G
Q
A
G
A
K
R
A
A
P
A
N
YGNARYRAIEPAPGRYVKAKA--------------------------------------------------
39
Fugue
44.49
14%
-73
* C4 *
-
5AF3
1
VPB45_MYCTU
A:
[11-238]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
F
D
------
V
P
L
Y
----
T
--
L
A
E
A
---
S
R
Y
L
V
-------------
V
P
R
--------
A
------
T
---
L
A
T
W
A
D
Q
P
I
I
T
A
L
P
H
P
T
---
G
S
H
----------------------------------------
A
----------
R
---------------
L
P
F
V
G
I
------
A
E
A
Y
V
L
N
A
F
---------------------
R
-----------
R
A
------
G
V
P
M
----------------------------------------------------------
Q
R
--------
I
R
--
P
S
--
L
D
----
W
L
I
K
N
-------
V
G
-----------
P
H
--
A
L
A
S
Q
D
--------------------------
L
-
C
-
T
D
G
A
E
-----
V
L
-
W
R
F
A
E
R
S
G
E
G
S
-----------------
P
D
--
D
-----
L
V
--
V
R
G
L
I
V
P
R
S
G
Q
Y
V
--
F
K
E
I
V
-
E
H
Y
L
Q
Q
I
S
-
F
-
A
D
--
D
N
L
A
S
M
I
R
L
P
Q
Y
-------
G
D
A
N
V
-
V
L
-
D
---------
P
R
R
G
Y
--
G
-
Q
P
---
V
F
D
--------
G
------------------------
S
-------------
G
V
R
V
---------
A
D
V
L
G
-----
P
L
R
A
G
A
T
F
Q
-
A
V
A
------------
D
D
Y
G
V
T
P
D
Q
L
R
D
A
L
D
A
-------------------------------------------------------------------------
1
PsiBlast_PDB
43.40
23%
-27
- C5 -
-
2HDW
-
Y2218_PSEAE
A:
[116-255]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
A
Q
T
-----
M
------
A
E
R
--------
G
------
F
---
V
T
L
A
F
D
P
S
---
Y
T
G
E
S
G
---
G
Q
P
R
N
V
--------
A
---------
S
P
D
I
N
T
E
D
F
S
A
A
V
D
F
I
---
S
----------
L
---------------
L
P
E
V
N
R
------
E
R
I
----------------------------------------
G
------
V
I
G
I
C
-
G
----------------------
W
-
G
--
G
M
A
L
N
A
V
A
V
-----------
D
----
K
R
V
K
A
--------
V
V
--
T
S
--
T
M
----
Y
D
M
T
R
V
M
S
KGYN
D
S
-----------
V
T
--
L
E
Q
R
T
R
T
L
E
---
Q
-----
L
-
G
Q
----
Q
---
R
W
K
D
A
-
E
S
G
T
P
-----
A
Y
-
Q
P
P
Y
N
E
L
K
G
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
42.20
16%
14
- C6 -
-
3WRY
1
?
A:
[8-431]
-------------------------------------------------------------------------------------------------------------------------------------------------------S
P
R
V
F
C
I
G
TADTK
F
D
E
L
R
F
L
S
E
H
V
R
S
S
L
N
S
F
S
N
KS
S
F
K
V
G
V
T
V
V
D
VSTSWKETNSCADFDFVP
S
K
D
V
L
S
C
HTLGEETMGTFAD
T
R
G
L
A
I
A
I
M
S
K
A
L
E
T
F
L
S
I
A
N
D
E
Q
NLA
G
V
I
G
L
G
G
S
G
G
T
S
L
L
S
S
A
F
R
S
L
P
I
G
I
------
P
K
V
I
----
I
--
S
T
V
A
---
S
G
Q
T
E
S
-----
Y
------
I
G
T
--------
S
------
D
---
L
V
L
F
P
S
V
V
D
I
C
G
I
N
N
V
S
---
K
V
V
L
S
N
--------
A
---------
G
A
A
-------
F
A
G
M
V
I
---
G
----------
R
---------------
L
E
S
K
F
T
------
V
G
V
T
M
F
-
G
V
---------------------
T
-----------
T
P
------
C
V
N
A
V
-
K
----------------------
E
-
R
--
L
V
K
E
G
Y
E
T
L
-----------
V
----
F
H
----------------------------------------------------------
A
T
G
---------------------------------
V
-----
G
G
-
R
A
M
E
D
L
V
R
G
G
F
-----------------
I
Q
--
G
-----
V
L
--
D
I
T
T
T
E
V
A
D
Y
V
V
G
--
G
V
M
A
C
-
D
S
S
R
F
D
A
I
-
L
-
E
K
K
I
P
L
V
L
S
V
G
A
L
D
---------------
M
V
-
N
F
G
P
K
T
T
I
--
P
P
E
F
Q
--
Q
-
R
K
---
I
H
E
--------
H
N
E
-------------------
Q
V
-
S
-------------
L
M
R
T
---------
T
-
V
G
E
-----
N
K
K
F
A
A
F
I
A
-
E
K
L
------------
N
K
A
S
-
S
S
V
C
V
C
L
P
E
K
G
V
S
ALDAPGKDFYD
P
E
A
T
S
C
L
T
R
E
L
Q
M
L
L
E
NNER
C
Q
V
K
V
L
PYHIND
A
E
F
A
N
A
L
V
D
S
F
L
E
I
S
PK-----------
40
Fugue
41.17
13%
15
- C2 -
-
1L9V
-
NSP2_ROTSR
A:
[1-313]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAE
L
A
C
F
C
------
Y
P
H
L
----
E
ND
S
Y
K
F
---
I
P
F
N
N
L
-----
A
------
I
K
A
M
L
T
AKVDK
K
------
D
---
M
D
K
F
Y
D
S
I
I
Y
G
I
A
P
P
P
Q
---
F
K
K
R
Y
N
--------
T
NDNSRGMNF
E
T
I
-------
M
F
T
K
V
A
---
M
----------
L
---------------
I
C
E
A
L
N
----------
S
L
K
V
T
---------------------
Q
-----------
A
N
------
V
S
N
V
L
-
S
----------------------
R
-
V
--
V
S
I
R
H
L
E
N
L
-----------
V
----
I
R
K
E
N
--------
P
Q
DI
L
F
--
H
S
----
K
D
L
L
L
-------
K
S
-----------
T
L
--
I
A
I
G
Q
S
K
E
I
---
E
-----
T
-
T
I
TAEG
G
---
E
I
V
-
F
-
Q
N
A
A
F
-----
T
M
-
W
K
L
T
Y
L
E
H
Q
L
M
-----------------
P
I
--
L
-----
D
Q
--
N
F
I
E
Y
K
V
T
L
N
E
D
K
PI
S
D
V
H
V
-
K
E
L
V
A
E
L
R
-
W
-
Q
Y
N
K
F
A
V
I
T
H
G
---
K
G
-------
H
Y
R
I
V
K
Y
S
-
S
V
A
N
H
A
D
R
--
V
Y
A
T
F
--
K
-
S
N
---
V
K
T
--------
G
-
V
NNDFNLLDQRIIW
Q
N
W
Y
A
F
T
S
-
S
-------------
M
K
Q
G
---------
N
T
L
D
V
-----
C
K
R
L
L
F
Q
K
M
-
K
P
E
------------
K
N
P
F
-
K
G
L
S
T
D
R
K
M
D
E
V
S
-----------------------------------------------------------------------
34
Fugue
40.88
11%
23
* C6 *
-
3BXW
-
CHID1_HUMAN
A:
[33-393]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLLEKSQF
S
D
K
P
V
------
Q
D
R
G
----
L
--
V
V
T
D
---
L
K
A
E
S
V
-----
V
------
L
E
H
--------
R
SYCSAK
A
---
R
D
R
H
F
A
G
D
V
L
G
Y
V
T
P
W
N
---
S
H
G
Y
D
V
--------
T
---------
K
V
F
-------
G
S
K
F
T
Q
---
I
----------
S
P
VW
L
Q
L
K
R
RGRE
M
F
E
V
T
G
L
H
D
------
V
D
Q
G
W
M
R
A
V
---------------------
R
-----------
K
H
A
KG
L
H
I
V
P
R
L
L
-
F
----------------------
E
-
D
--
W
T
Y
D
D
F
R
N
V
-----------
L
D
S
E
D
E
I
E
E
L
--------
S
K
--
T
V
--
V
Q
----
V
A
K
N
Q
HF-----
D
G
-----------
F
V
--
V
E
V
W
N
Q
L
L
S
---
Q
-----
R
-
V
G
----
L
---
I
H
M
-
L
-
T
H
L
A
E
-----
A
L
-
H
Q
A
R
L
L
A
L
L
V
I
P
P
AITPGTDQLGMFT
H
K
E
F
--
E
-----
Q
L
AP
V
L
D
G
F
S
L
M
T
Y
D
Y
S
--
T
A
H
Q
P
-
G
P
N
A
P
L
S
W
-
V
-
R
A
C
V
Q
V
L
D
P
K
S
K
W
R
S
K
IL
L
G
L
N
F
Y
G
M
D
Y
-
A
T
-
S
K
D
A
R
E
P
V
--
V
G
A
R
Y
--
I
-
Q
T
---
L
K
D
--------
H
-
R
-------------------
P
R
M
V
-------------
W
D
S
Q
---------
A
S
E
H
F
-----
F
E
Y
K
K
S
R
S
G
-
R
H
V
------------
V
F
Y
P
-
T
L
K
S
L
Q
V
R
L
E
L
A
R
E
L
G
V
G
V
S
I
WELGQGLDYFYDLL-------------------------------------------------
2
PsiBlast_PDB
39.31
38%
-82
- C5 -
-
4A3C
-
RPB1_YEAST
A:
[915-988]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
G
S
E
I
L
-
G
D
L
K
L
Q
V
L
-
L
-
D
E
E
----
Y
K
Q
L
V
K
D
R
K
-------
F
L
R
E
V
-
F
V
-
D
G
E
A
N
W
P
L
--
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
37.92
38%
-84
- C5 -
-
1I3Q
-
RPB1_YEAST
A:
[915-987]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
G
S
E
I
L
-
G
D
L
K
L
Q
V
L
-
L
-
D
E
E
----
Y
K
Q
L
V
K
D
R
K
-------
F
L
R
E
V
-
F
V
-
D
G
E
A
N
W
P
L
--
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
37.78
38%
-96
- C5 -
-
4A3G
-
RPB1_YEAST
A:
[915-988]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
G
S
E
I
L
-
G
D
L
K
L
Q
V
L
-
L
-
D
E
E
----
Y
K
Q
L
V
K
D
R
K
-------
F
L
R
E
V
-
F
V
-
D
G
E
A
N
W
P
L
--
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
37.32
38%
-102
- C5 -
-
1K83
-
RPB1_YEAST
A:
[915-988]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
G
S
E
I
L
-
G
D
L
K
L
Q
V
L
-
L
-
D
E
E
----
Y
K
Q
L
V
K
D
R
K
-------
F
L
R
E
V
-
F
V
-
D
G
E
A
N
W
P
L
--
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
37.11
38%
-71
- C5 -
-
4A93
-
RPB1_YEAST
A:
[915-988]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
G
S
E
I
L
-
G
D
L
K
L
Q
V
L
-
L
-
D
E
E
----
Y
K
Q
L
V
K
D
R
K
-------
F
L
R
E
V
-
F
V
-
D
G
E
A
N
W
P
L
--
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
37.03
38%
-103
- C5 -
-
4A3L
-
RPB1_YEAST
A:
[915-985]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
G
S
E
I
L
-
G
D
L
K
L
Q
V
L
-
L
-
D
E
E
----
Y
K
Q
L
V
K
D
R
K
-------
F
L
R
E
V
-
F
V
-
D
G
E
A
N
W
P
L
--
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
36.97
38%
-81
- C5 -
-
4A3J
-
RPB1_YEAST
A:
[915-985]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
G
S
E
I
L
-
G
D
L
K
L
Q
V
L
-
L
-
D
E
E
----
Y
K
Q
L
V
K
D
R
K
-------
F
L
R
E
V
-
F
V
-
D
G
E
A
N
W
P
L
--
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
36.10
38%
-85
- C5 -
-
1I50
-
RPB1_YEAST
A:
[915-987]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
G
S
E
I
L
-
G
D
L
K
L
Q
V
L
-
L
-
D
E
E
----
Y
K
Q
L
V
K
D
R
K
-------
F
L
R
E
V
-
F
V
-
D
G
E
A
N
W
P
L
--
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
35.58
38%
-87
- C5 -
-
4A3D
-
RPB1_YEAST
A:
[915-988]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
G
S
E
I
L
-
G
D
L
K
L
Q
V
L
-
L
-
D
E
E
----
Y
K
Q
L
V
K
D
R
K
-------
F
L
R
E
V
-
F
V
-
D
G
E
A
N
W
P
L
--
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------