@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKW8: (2017-10-30 )
MEKSVTQENSVPVIGQRFRGFLPVVVDVETAGFNAQTDALLEIACIPIVYDAQGQFVPGPAFHAHINPFEGANLDRRSLDFIGIDPFNPMRIAMAEDERTALRRIFKSVNEVRKQQHCTHAVLVGHNAHFDLGFLQAAIARSGTKNQNPFHSFSVMDTVTLSAVMFGQTVLAKACIQAGIEFDGKEAHSALYDTQKTAELFCYILNKLSPYLLDSLVAAS
Atome Classification :
(36 SA)
.........10........20........30........40........50........60........70........80........90.........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MEKSVTQENSV
P
V
I
G
Q
R
FRGF
L
P
V
V
V
D
V
ETAGFNAQT
D
A
L
L
E
I
A
C
I
P
I
V
YDAQGQFVPGPA
F
H
A
HINPFEGANLDRRSL
D
F
I
GIDPFN
P
M
-
R
I
A
MAE
D
E
R
T
A
L
R
R
I
F
K
S
V
N
E
V
R
K
Q
QHC
T
H
A
V
L
VGHNAH
F
D
L
G
F
L
Q
A
A
I
ARSGTKNQNPFH
S
F
S
V
M
D
T
V
T
L
S
A
V
M
F
G
Q
T
V
L
A
K
A
C
I
Q
AGIEFD
G
K
E
A
H
S
A
L
YD
T
Q
K
T
A
E
L
F
C
Y
I
L
N
KL
S
P
Y
L
L
D
S
L
VAAS
36
PsiBlast_CBE
95.32
53%
-134
- C1 -
-
3VA3
2
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
32
PsiBlast_CBE
94.53
54%
-134
- C1 -
-
3NH1
2
RNT_ECOLI
D:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
9
PsiBlast_PDB
94.45
54%
-135
- C1 -
-
4KAZ
1
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
27
PsiBlast_CBE
94.16
54%
-130
- C1 -
-
3V9X
2
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
11
PsiBlast_PDB
93.82
54%
-135
- C1 -
-
4KB1
-
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
40
PsiBlast_CBE
93.22
53%
-132
- C1 -
-
3V9U
2
RNT_ECOLI
D:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
3
PsiBlast_PDB
93.22
54%
-136
- C1 -
-
3NH1
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
16
PsiBlast_PDB
93.19
53%
-135
- C1 -
-
3VA3
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
24
PsiBlast_CBE
93.18
54%
-133
- C1 -
-
3V9Z
2
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
25
PsiBlast_CBE
92.91
54%
-132
- C1 -
-
3V9X
2
RNT_ECOLI
D:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
10
PsiBlast_PDB
92.91
54%
-135
- C1 -
-
4KB0
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
37
PsiBlast_CBE
92.82
53%
-136
- C1 -
-
3V9W
2
RNT_ECOLI
D:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
31
PsiBlast_CBE
92.75
54%
-137
- C1 -
-
3NH2
3
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
8
PsiBlast_PDB
92.73
54%
-134
- C1 -
-
3VA0
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
38
PsiBlast_CBE
92.65
53%
-136
- C1 -
-
3V9W
2
RNT_ECOLI
C:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
13
PsiBlast_PDB
92.59
53%
-135
- C1 -
-
3NGZ
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
2
PsiBlast_PDB
92.58
54%
-132
- C1 -
-
3NH0
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
15
PsiBlast_PDB
92.56
53%
-137
- C1 -
-
3V9W
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
34
PsiBlast_CBE
92.42
54%
-130
- C1 -
-
3NH1
2
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
6
PsiBlast_PDB
92.29
54%
-129
- C1 -
-
3V9X
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
7
PsiBlast_PDB
92.25
54%
-134
- C1 -
-
3V9Z
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
30
PsiBlast_CBE
92.18
54%
-133
- C1 -
-
3NH2
3
RNT_ECOLI
E:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
22
PsiBlast_CBE
91.84
54%
-135
- C1 -
-
4KB0
2
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
5
PsiBlast_PDB
91.69
54%
-131
- C1 -
-
3V9S
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
23
PsiBlast_CBE
91.55
54%
-132
- C1 -
-
3VA0
2
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
26
PsiBlast_CBE
91.22
54%
-134
- C1 -
-
3V9X
2
RNT_ECOLI
C:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
35
PsiBlast_CBE
91.20
54%
-131
- C1 -
-
3NH0
2
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
39
PsiBlast_CBE
91.14
53%
-132
- C1 -
-
3V9W
2
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
28
PsiBlast_CBE
91.13
54%
-131
- C1 -
-
3V9S
2
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
33
PsiBlast_CBE
91.02
54%
-131
- C1 -
-
3NH1
2
RNT_ECOLI
C:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
41
PsiBlast_CBE
90.09
53%
-131
- C1 -
-
3V9U
2
RNT_ECOLI
C:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
29
PsiBlast_CBE
89.86
54%
-137
- C1 -
-
3NH2
3
RNT_ECOLI
F:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
-----
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
14
PsiBlast_PDB
89.71
53%
-135
- C1 -
-
3V9U
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
42
PsiBlast_CBE
88.38
53%
-135
- C1 -
-
3V9U
2
RNT_ECOLI
B:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
G
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
4
PsiBlast_PDB
86.22
54%
-141
- C1 -
-
3NH2
2
RNT_ECOLI
A:
[33-221]
----------------
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
N
D
P
D
-
R
G
A
V
S
E
Y
E
--
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
-
R
N
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
-----
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
------------
55
HHSearch
84.98
50%
-82
- C1 -
-
3V9W
2
RNT_ECOLI
D:
[26-232]
---------
Q
L
T
G
L
C
D
R
F
R
G
F
Y
P
V
V
I
D
V
E
T
A
G
F
N
A
K
T
D
A
L
L
E
I
A
A
I
T
L
K
M
D
E
Q
G
W
L
M
P
D
T
T
L
H
F
H
V
E
P
F
V
G
A
N
L
Q
P
E
A
L
A
F
N
G
I
D
P
-
N
D
P
D
R
G
A
V
--
S
G
Y
E
A
L
H
E
I
F
K
V
V
R
K
G
I
K
A
S
G
C
N
R
A
I
M
V
A
H
N
A
N
F
D
H
S
F
M
M
A
A
A
E
R
A
S
L
K
R
N
-
P
F
H
P
F
A
T
F
D
T
A
A
L
A
G
L
A
L
G
Q
T
V
L
S
K
A
C
Q
T
A
G
M
D
F
D
S
T
Q
A
H
S
A
L
Y
D
T
E
R
T
A
V
L
F
C
E
I
V
N
R
W
K
R
L
G
G
W
P
L
S
A
A
-