@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMQ8: (2017-11-09 )
MSTDIQLNLIGRTQELFVEDIQHWNNKLIEIVSSSKFLVLGGAGSIGQAVVKEIFKRNPKKLHVVDISENNLTEVVRDIRSSFGYIDGDFQTFALDIGSAEYDAYIENDGDFDYVLNLSALKHVRSEKDPFTLMRMIHVNILNTEKTIQQSIAKGVKKYFCVSTDKAANPVNMMGGSKRIMEMFLMRQSQYIDISTARFANVAFSDGSLLHGFNQRIQKNQPIAAPNDIRRYFVTPKESGELCLMSCLLGENRDIFFPKLSEHLHLITFADIAVKYLNNLGYEPYLCESEDEARSLIQTLPKQGKWPCLFAGSTTTGEKDFEEFFTDNETLDMQRFNNLGVIKNELNIEEDKLQVFEEKINSMLLSKHWNKEEIVDLFNYMMPNFGHKETGLYLDGKM
Atome Classification :
(20 SA)
.........10........20........30........40........50......-..60........70........80.-.......90........100.......-110.......120....-...130..---.....140.......150-----..--.....160......----------------.170.......180.......190---.---..-----......200......------.210.......220.--....--.-..230.......240.......250.......260......---.270.......280.......290.......300.......310-.......320.......330.......340.......350.......360.......370.......380.......390......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MST
D
I
Q
L
N
L
IG
R
T
Q
E
L
F
V
E
D
I
Q
H
W
N
N
K
L
I
E
I
VSSS
K
F
L
V
LGGA
G
S
I
G
Q
A
V
V
K
E
I
F
KR-NP
K
K
L
H
V
V
DISEN
N
L
T
E
V
V
R
D
I
R
S
S-FGYIDGD
F
Q
T
F
A
L
DIGSAE
Y
D
A
Y
IEND-GDF
D
Y
V
L
N
L
S
A
L
K
H
V
RS-EK
D
P
F
T
L
M
---
R
M
I
H
V
N
ILN
T
E
K
T
I
Q
Q
S
I
-----
A
K
--
G
V
K
K
Y
F
C
VSTDKAA----------------N
P
V
NMMGG
S
K
R
I
M
E
M
F
L
M
RQS
Q
-----
Y
---
I
D-----IST
A
R
F
A
N
V
AFSDG
S
------
L
L
H
G
F
N
Q
R
I
QKN-QP--IAAP--
N
-
D
I
R
R
Y
FVTPKESG
E
L
C
L
M
S
C
L
LGENRDIF
F
P
K
L
S
E
H
L
H
L
I
T
---
F
A
D
I
A
V
K
Y
L
N
NLGYEPYLCES
E
D
E
A
R
S
L
I
Q
TLPKQGKW
P
C
L
FAG-STTTG
E
K
D
F
E
E
FFTDNET
L
D
M
Q
RFNNLGVIKNELNI
E
E
D
K
L
Q
V
F
E
E
K
I
N
S
M
L
L
S
KHW
N
K
E
E
I
V
D
L
F
N
Y
MMPNFGHKET
G
L
Y
LDGKM
1
PsiBlast_PDB
87.37
74%
-124
- C1 -
-
3PVZ
2
?
A:
[8-386]
------
L
S
L
I
G
R
D
T
E
L
F
H
Q
D
I
N
A
N
E
K
E
L
Q
S
V
V
S
Q
S
R
F
L
V
L
G
G
A
G
S
I
G
Q
A
V
T
K
E
I
F
K
R
-
N
P
Q
K
L
H
V
V
D
I
S
E
N
N
M
V
E
L
V
R
D
I
R
S
S
-
F
G
Y
I
N
G
D
F
Q
T
F
A
L
D
I
G
S
I
E
Y
D
A
F
I
K
A
D
-
G
Q
Y
D
Y
V
L
N
L
S
A
L
K
H
V
R
S
-
E
K
D
P
F
T
L
M
---
R
M
I
D
V
N
V
F
N
T
D
K
T
I
Q
Q
S
I
-----
D
A
--
G
A
K
K
Y
F
C
V
S
T
D
K
A
A
----------------
N
P
V
N
M
M
G
A
S
K
R
I
M
E
M
F
L
M
R
K
S
E
-----
E
---
I
A
-----
I
S
T
A
R
F
A
N
V
A
F
S
D
G
S
------
L
L
H
G
F
N
Q
R
I
Q
K
N
-
Q
P
--
I
V
A
P
--
N
-
D
I
K
R
Y
F
V
T
P
Q
E
S
G
E
L
C
L
M
S
C
I
F
G
E
N
R
D
I
F
F
P
K
L
S
E
A
L
H
L
I
S
---
F
A
D
I
A
V
K
Y
L
K
Q
L
G
Y
E
P
H
L
C
E
S
E
D
E
A
R
E
L
A
K
T
L
P
A
Q
G
K
W
P
C
L
F
T
S
-
S
---------
E
F
F
T
D
K
E
T
L
D
M
A
R
F
D
N
L
G
I
I
K
N
D
S
L
Y
Q
Q
E
L
L
E
L
F
E
Q
K
I
G
Q
M
K
T
D
R
Q
W
T
K
E
E
I
V
Q
L
F
F
I
M
I
P
D
F
-------------
53
HHSearch
78.84
76%
-16
- C1 -
-
3PVZ
2
?
A:
[10-386]
--------
L
I
G
R
D
T
E
L
F
H
Q
D
I
N
A
N
E
K
E
L
Q
S
V
V
S
Q
S
R
F
L
V
L
G
G
A
G
S
I
G
Q
A
V
T
K
E
I
F
K
R
-
N
P
Q
K
L
H
V
V
D
I
S
E
N
N
M
V
E
L
V
R
D
I
R
S
S
-
F
G
Y
I
N
G
D
F
Q
T
F
A
L
D
I
G
S
I
E
Y
D
A
F
I
K
A
D
-
G
Q
Y
D
Y
V
L
N
L
S
A
L
K
H
V
R
S
--
E
K
--
D
P
F
T
L
M
R
M
I
D
V
N
V
F
N
T
D
K
T
I
Q
Q
S
I
-----
D
A
--
G
A
K
K
Y
F
C
V
S
T
D
K
A
A
----------------
N
P
V
N
M
M
G
A
S
K
R
I
M
E
M
F
L
M
R
K
S
E
-----
E
---
I
A
-----
I
S
T
A
R
F
A
N
V
A
F
S
D
G
S
------
L
L
H
G
F
N
Q
R
I
Q
K
N
-
Q
P
--
I
-
V
A
P
-
N
-
D
I
K
R
Y
F
V
T
P
Q
E
S
G
E
L
C
L
M
S
C
I
F
G
E
N
R
D
I
F
F
P
K
L
S
E
A
L
---
H
L
I
S
F
A
D
I
A
V
K
Y
L
K
Q
L
G
Y
E
P
H
L
C
E
S
E
D
E
A
R
E
L
A
K
T
L
P
A
Q
G
K
W
P
C
L
F
T
S
S----------
E
F
F
T
D
K
E
T
L
D
M
A
R
F
D
N
L
G
I
I
K
N
D
S
L
Y
Q
Q
E
L
L
E
L
F
E
Q
K
I
G
Q
M
K
T
D
R
Q
W
T
K
E
E
I
V
Q
L
F
F
I
M
I
P
D
F
-------------
55
HHSearch
47.46
27%
-30
* C1 *
-
4G5H
15
?
A:
[18-302]
--------------------------
G
S
A
M
G
F
D
D
K
I
L
L
I
T
G
G
T
G
S
F
G
N
A
V
M
K
R
F
L
D
S
-
N
I
K
E
I
R
I
F
S
R
D
E
K
K
Q
D
D
I
R
K
K
Y
N
N
-------
S
K
L
K
F
Y
I
G
D
V
R
D
S
Q
S
V
E
T
A
M
R
---
D
V
D
Y
V
F
H
A
A
A
L
K
Q
V
P
S
-
C
E
F
--
F
P
V
---
E
A
V
K
T
N
I
I
G
T
E
N
V
L
Q
S
A
I
-----
H
Q
--
N
V
K
K
V
I
C
L
S
T
D
K
A
A
----------------
Y
P
I
N
A
M
G
I
S
K
A
M
M
E
K
V
F
V
A
K
S
R
N
I
RSE
Q
---
T
L
-----
I
C
G
T
R
Y
G
N
V
M
A
S
R
G
S
------
V
I
P
L
F
I
D
K
I
K
A
G
-
E
P
--
L
T
I
T
D-
P
-
D
M
T
R
F
L
M
S
L
E
D
A
V
E
L
V
V
H
A
F
K
H
A
E
T
G
D
I
M
V
Q
K
-
A
P
S
S
---
T
---
V
G
D
L
A
T
A
L
L
E
L
F
E
A
D
----------------------
N
A
I
E
I
I
G
-
T
-
R
H
G
E
K
K
A
E
T
L
L
T
R
E
E
Y
A
Q
C
E
D
M
G
D
Y
F
R
V
--------------------------------------------------------
57
HHSearch
46.94
24%
-24
- C1 -
-
2GN4
3
PSEB_HELPY
A:
[16-298]
----------------------------
Q
N
M
L
D
N
Q
T
I
L
I
T
G
G
T
G
S
F
G
K
C
F
V
R
K
V
L
D
T
T
N
A
K
K
I
I
V
Y
S
R
D
E
L
K
Q
S
E
M
A
M
E
F
N
D
-------
P
R
M
R
F
F
I
G
D
V
R
D
L
E
R
L
N
Y
A
L
E
---
G
V
D
I
C
I
H
A
A
A
L
K
H
V
P
I
-
A
E
Y
--
N
P
L
---
E
C
I
K
T
N
I
M
G
A
S
N
V
I
N
A
C
L
-----
K
N
--
A
I
S
Q
V
I
A
L
S
T
D
K
A
A
----------------
N
P
I
N
L
Y
G
A
T
K
L
C
S
D
K
L
F
V
S
A
N
N
FKGS
S
Q
---
T
Q
-----
F
S
V
V
R
Y
G
N
V
V
G
S
R
G
S
------
V
V
P
F
F
K
K
L
V
Q
N
K
A
S
E
--
I
P
I
T
D-
I
-
R
M
T
R
F
W
I
T
L
D
E
G
V
S
F
V
L
K
S
L
K
R
M
H
G
G
E
I
F
V
-
P
K
I
P
S
M
---
K
---
M
T
D
L
A
K
A
L
A
P
N
T
P
T
--------------------------
K
I
I
G
-
I
-
R
P
G
E
K
L
H
E
V
M
I
P
K
D
E
S
H
L
A
L
E
F
E
D
F
F
I
I
Q
P
------------------------------------------------------
56
HHSearch
46.85
27%
-28
- C1 -
-
3W1V
2
?
A:
[18-302]
--------------------------
G
S
A
M
G
F
D
D
K
I
L
L
I
T
G
G
T
G
S
F
G
N
A
V
M
K
R
F
L
D
S
-
N
I
K
E
I
R
I
F
S
R
D
E
K
K
Q
D
D
I
R
K
K
Y
N
N
-------
S
K
L
K
F
Y
I
G
D
V
R
D
S
Q
S
V
E
T
A
M
R
---
D
V
D
Y
V
F
H
A
A
A
L
K
Q
V
P
S
-
C
E
F
--
F
P
V
---
E
A
V
K
T
N
I
I
G
T
E
N
V
L
Q
S
A
I
-----
H
Q
--
N
V
K
K
V
I
C
L
S
T
D
K
A
A
----------------
Y
P
I
N
A
M
G
I
S
K
A
M
M
E
K
V
F
V
A
K
S
R
NIRSE
Q
---
T
L
-----
I
C
G
T
R
Y
G
N
V
M
A
S
R
G
S
------
V
I
P
L
F
I
D
K
I
K
A
G
-
E
P
--
L
T
I
T
D-
P
-
D
M
T
R
F
L
M
S
L
E
D
A
V
E
L
V
V
H
A
F
K
H
A
E
T
G
D
I
M
V
Q
K
-
A
P
S
S
---
T
---
V
G
D
L
A
T
A
L
L
E
L
F
E
A
D
----------------------
N
A
I
E
I
I
G
-
T
-
R
H
G
E
K
K
A
E
T
L
L
T
R
E
E
Y
A
Q
C
E
D
M
G
D
Y
F
R
V
--------------------------------------------------------
21
PsiBlast_CBE
45.71
31%
-31
- C1 -
-
3W1V
2
?
B:
[28-260]
------------------------------------
L
L
I
T
G
G
T
G
S
F
G
N
A
V
M
K
R
F
L
D
S
-
N
I
K
E
I
R
I
F
S
R
D
E
K
K
Q
D
----
D
I
R
K
K
-
Y
N
N
S
K
L
K
F
Y
-----
I
G
D
V
R
D
S
Q
S
V
E
T
A
M
R
D
V
D
Y
V
F
H
A
A
A
L
K
Q
V
P
S
-
C
E
--
F
F
P
V
---
E
A
V
K
T
N
I
I
G
T
E
N
V
L
Q
S
A
I
-----
H
Q
--
N
V
K
K
V
I
C
L
S
T
D
K
A
A
----------------
Y
P
I
N
A
M
G
I
S
K
A
M
M
E
K
V
F
V
A
K
S
R
-----
N
---
I
R
SEQTL
I
C
G
T
R
Y
G
N
V
M
A
S
R
G
S
------
V
I
P
L
F
I
D
K
I
K
A
G
-
E
P
--
L
T
I
T
--
D
P
D
M
T
R
F
L
M
S
L
E
D
A
V
E
L
V
V
H
A
F
K
H
A
E
T
G
D
I
M
V
Q
K
A
P
S
S
----
T
---
V
G
D
L
A
T
A
L
L
--------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
45.56
31%
-31
- C1 -
-
4G5H
13
?
A:
[28-260]
------------------------------------
L
L
I
T
G
G
T
G
S
F
G
N
A
V
M
K
R
F
L
D
S
-
N
I
K
E
I
R
I
F
S
R
D
E
K
K
Q
D
----
D
I
R
K
K
-
Y
N
N
S
K
L
K
F
Y
-----
I
G
D
V
R
D
S
Q
S
V
E
T
A
M
R
D
V
D
Y
V
F
H
A
A
A
L
K
Q
V
P
S
-
C
E
--
F
F
P
V
---
E
A
V
K
T
N
I
I
G
T
E
N
V
L
Q
S
A
I
-----
H
Q
--
N
V
K
K
V
I
C
L
S
T
D
K
A
A
----------------
Y
P
I
N
A
M
G
I
S
K
A
M
M
E
K
V
F
V
A
K
S
R
-----
N
---
I
R
SEQ
T
L
I
C
G
T
R
Y
G
N
V
M
A
S
R
G
S
------
V
I
P
L
F
I
D
K
I
K
A
G
-
E
P
--
L
T
I
T
--
D
P
D
M
T
R
F
L
M
S
L
E
D
A
V
E
L
V
V
H
A
F
K
H
A
E
T
G
D
I
M
V
Q
K
A
P
S
S
----
T
---
V
G
D
L
A
T
A
L
L
--------------------------------------------------------------------------------------------------------------------------
75
Fugue
45.35
23%
0
- C1 -
-
2GN4
3
PSEB_HELPY
A:
[16-344]
----------------------------
Q
N
M
L
D
N
Q
T
I
L
I
T
G
G
T
G
S
F
G
K
C
F
V
R
K
V
L
D
T
T
N
A
K
K
I
I
V
Y
S
R
D
E
L
K
Q
S
E
M
A
M
E
F
N
D
P
-------
R
M
R
F
F
I
G
D
V
R
D
L
E
R
L
N
Y
A
L
E
G
---
V
D
I
C
I
H
A
A
A
L
K
H
V
P
I
-
A
E
Y
--
N
P
L
---
E
C
I
K
T
N
I
M
G
A
S
N
V
I
N
A
C
L
-----
K
N
--
A
I
S
Q
V
I
A
L
S
T
D
K
A
A
----------------
N
P
I
N
L
Y
G
A
T
K
L
C
S
D
K
L
F
V
S
A
N
N
-----
F
---
K
G
S
S
Q
T
Q
F
S
V
V
R
Y
G
N
V
V
G
S
R
G
S
------
V
V
P
F
F
K
K
L
V
Q
N
K
A
S
E
--
I
P
I
T
--
D
I
R
M
T
R
F
W
I
T
L
D
E
G
V
S
F
V
L
K
S
L
K
R
M
H
G
G
E
I
F
V
P
K
I
P
----
S
M
K
---
M
T
D
L
A
K
A
L
A
P
N
T
------------------
P
T
K
I
I
G
I
R
P
----------
G
E
K
L
H
E
V
M
I
P
K
D
E
S
H
L
A
L
E
F
E
D
F
F
I
I
Q
P
T
I
S
F
Q
T
P
K
D
Y
T
L
T
K
L
H
E
K
G
--------
Q
K
V
A
P
D
F
E
Y
S
S
H
N
N
N
Q
W
L
E
P
D
D
L
L
K
L
L
4
PsiBlast_PDB
44.99
30%
-30
- C1 -
-
3VVC
1
?
A:
[28-280]
------------------------------------
L
L
I
T
G
G
T
G
S
F
G
N
A
V
M
K
R
F
L
D
S
-
N
I
K
E
I
R
I
F
S
R
D
E
K
K
Q
D
----
D
I
R
K
K
-
Y
N
N
S
K
L
K
F
Y
-----
I
G
D
V
R
D
S
Q
S
V
E
T
A
M
R
D
V
D
Y
V
F
H
A
A
A
L
K
Q
V
P
S
-
C
E
--
F
F
P
V
---
E
A
V
K
T
N
I
I
G
T
E
N
V
L
Q
S
A
I
-----
H
Q
--
N
V
K
K
V
I
C
L
S
T
D
E
A
A
----------------
Y
P
I
N
A
M
G
I
S
K
A
M
M
E
K
V
F
V
A
K
S
R
-----
N
---
I
R
SEQ
T
L
I
C
G
T
R
Y
G
N
V
M
A
S
R
G
S
------
V
I
P
L
F
I
D
K
I
K
A
G
-
E
P
--
L
T
I
T
--
D
P
D
M
T
R
F
L
M
S
L
E
D
A
V
E
L
V
V
H
A
F
K
H
A
E
T
G
D
I
M
V
Q
K
A
P
S
S
----
T
---
V
G
D
L
A
T
A
L
L
--------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
44.52
31%
-28
- C1 -
-
3W1V
2
?
A:
[28-260]
------------------------------------
L
L
I
T
G
G
T
G
S
F
G
N
A
V
M
K
R
F
L
D
S
-
N
I
K
E
I
R
I
F
S
R
D
E
K
K
Q
D
----
D
I
R
K
K
-
Y
N
N
S
K
L
K
F
Y
-----
I
G
D
V
R
D
S
Q
S
V
E
T
A
M
R
D
V
D
Y
V
F
H
A
A
A
L
K
Q
V
P
S
-
C
E
--
F
F
P
V
---
E
A
V
K
T
N
I
I
G
T
E
N
V
L
Q
S
A
I
-----
H
Q
--
N
V
K
K
V
I
C
L
S
T
D
K
A
A
----------------
Y
P
I
N
A
M
G
I
S
K
A
M
M
E
K
V
F
V
A
K
S
R
-----
N
---
I
R
SEQ
T
L
I
C
G
T
R
Y
G
N
V
M
A
S
R
G
S
------
V
I
P
L
F
I
D
K
I
K
A
G
-
E
P
--
L
T
I
T
--
D
P
D
M
T
R
F
L
M
S
L
E
D
A
V
E
L
V
V
H
A
F
K
H
A
E
T
G
D
I
M
V
Q
K
A
P
S
S
----
T
---
V
G
D
L
A
T
A
L
L
--------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
41.91
29%
-40
- C1 -
-
4J2O
2
PYRRH_PYRAP
A:
[26-264]
------------------------------------
L
L
I
T
G
G
T
G
S
F
G
N
A
V
L
K
R
F
L
E
T
-
D
I
K
E
I
R
I
F
S
R
D
E
K
K
Q
D
D
M
R
K
K
Y
H
S
A
K
L
K
F
Y
I
G
D
V
R
---------
D
Y
N
S
I
L
N
A
T
-
R
G
V
D
Y
I
Y
H
A
A
A
L
K
Q
V
P
S
-
C
E
--
F
H
P
M
---
E
A
V
K
T
N
V
L
G
T
E
N
V
L
E
A
A
I
-----
Q
N
--
H
V
K
R
V
V
C
L
S
T
D
K
A
V
----------------
Y
P
I
N
A
M
G
I
S
K
A
M
M
E
K
V
M
V
A
K
S
R
-----
N
---
L
E
GLD
T
V
I
C
G
T
R
Y
G
N
V
M
A
S
R
G
S
------
V
I
P
L
F
V
D
Q
I
R
Q
G
-
K
P
LT
I
T
D
P
--
N
-
M
T
-
R
F
M
M
T
L
E
D
A
V
D
L
V
L
Y
A
F
E
H
G
E
N
G
D
I
F
V
Q
K
-----------------------------------------------------------------------------------------------------------------------------------------------
73
HHSearch
41.50
24%
-55
- C1 -
-
4ZRN
2
?
A:
[4-261]
----------------------------------
M
N
I
L
V
T
G
G
A
G
F
I
G
S
H
V
V
D
K
L
I
E
N
-
G
-
Y
G
V
I
V
V
D
N
L
S
S
G
K
V
E
---
N
L
N
--------
R
N
A
L
F
Y
E
Q
S
I
E
D
E
E
M
M
E
R
I
F
S
L
-
H
R
P
E
Y
V
F
H
L
A
A
Q
A
S
V
A
I
-
S
V
R
--
E
P
A
---
R
D
A
K
T
N
I
I
G
S
L
V
L
L
E
K
S
I
-----
K
Y
--
G
V
K
K
F
I
F
S
S
T
G
G
A
I
YGENVKVFPTPETE
I
P
H
P
I
S
P
Y
G
I
A
K
Y
S
T
E
M
Y
L
E
F
F
A
R
E
Y---
G
---
L
K
-----
Y
T
V
L
R
Y
A
N
V
Y
G
P
R
Q
D
PYGEAG
V
V
A
I
F
T
E
R
M
L
R
G
-
E
E
--
V
H
I
F
G
D
G
-
E
Y
V
R
D
Y
V
Y
V
D
D
V
V
R
A
N
L
L
A
M
E
K
G
-
D
N
E
V
F
N
I
G
T
G
R
G
T
---
T
---
V
N
Q
L
F
K
L
L
K
E
I
T
G
Y
D
--------------------------------------------------------------------------------------------------------------------
72
HHSearch
40.96
24%
-56
- C1 -
-
4ZRM
2
?
B:
[3-261]
---------------------------------
H
M
N
I
L
V
T
G
G
A
G
F
I
G
S
H
V
V
D
K
L
I
E
N
-
G
-
Y
G
V
I
V
V
D
N
L
S
S
G
K
V
E
---
N
L
N
--------
R
N
A
L
F
Y
E
Q
S
I
E
D
E
E
M
M
E
R
I
F
S
L
-
H
R
P
E
Y
V
F
H
L
A
A
Q
A
S
V
A
I
-
S
V
R
--
E
P
A
---
R
D
A
K
T
N
I
I
G
S
L
V
L
L
E
K
S
I
-----
K
Y
--
G
V
K
K
F
I
F
S
S
T
G
G
A
I
Y
GENVKVFPTPETE
I
P
H
P
I
S
P
Y
G
I
A
K
Y
S
T
E
M
Y
L
E
F
F
A
R
E
Y---
G
---
L
K
-----
Y
T
V
L
R
Y
A
N
V
Y
G
P
R
Q
D
PYGEAG
V
V
A
I
F
T
E
R
M
L
R
G
-
E
E
--
V
H
I
F
GD
G
-
E
Y
V
R
D
Y
V
Y
V
D
D
V
V
R
A
N
L
L
A
M
E
K
G
-
D
N
E
V
F
N
I
G
T
G
R
G
T
---
T
---
V
N
Q
L
F
K
L
L
K
E
I
T
G
Y
D
--------------------------------------------------------------------------------------------------------------------
76
Fugue
40.67
21%
-18
- C1 -
-
4TQG
1
?
A:
[1-319]
---------------------
S
Q
I
N
D
K
--------
T
I
M
I
F
G
G
S
G
S
L
G
N
R
L
I
E
T
Y
I
N
N
-
N
----
I
I
V
N
Y
S
R
D
--
E
S
K
H
W
S
M
E
L
K
-
Y
K
--
S
D
K
L
K
N
I
I
G
D
I
R
D
F
E
K
V
Q
Q
S
I
M
R
-
I
N
P
D
I
I
I
I
A
A
A
L
K
H
I
D
R
C
E
Y
E
I
N
E
C
L
---
D
T
N
I
K
G
L
Q
N
V
L
K
V
T
E
I
N
R
-----
S
N
LS
N
L
K
A
V
C
F
V
S
T
D
K
A
C
----------------
S
P
V
N
S
Y
G
M
S
K
A
I
C
E
T
L
V
V
E
K
S
K
-----
Y
I
KD
I
K
-----
Y
V
C
V
R
Y
G
N
V
-----------------------
L
-
N
F
--
T
L
T
H
--
T
-
S
M
T
R
F
I
M
T
L
D
D
S
V
K
L
I
E
Y
A
I
I
N
G
N
S
G
E
I
V
I
P
K
L
N
---------------------------
S
M
Y
I
K
D
M
I
E
L
F
A
D
K
Y
P
I
V
I
T
--------
G
L
R
S
G
E
R
M
Y
E
S
L
I
N
D
T
Q
S
M
K
T
V
P
K
G
D
Y
Y
H
I
L
P
T
Y
D
P
T
I
V
T
E
E
F
Y
E
Y
S
S
K
Q
N
I
L
S
----
K
Q
E
L
E
N
Y
L
N
Q
------------------
49
PsiBlast_CBE
40.43
34%
-186
- C1 -
-
2Q1U
1
?
A:
[30-78]
-------------------------------
L
A
N
T
N
V
M
V
V
G
G
A
G
F
V
G
S
N
L
V
K
R
L
L
E
L
-
G
V
N
Q
V
H
V
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
40.40
34%
-183
- C1 -
-
2Q1T
1
?
A:
[30-82]
-------------------------------
L
A
N
T
N
V
M
V
V
G
G
A
G
F
V
G
S
N
L
V
K
R
L
L
E
L
-
G
V
N
Q
V
H
V
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
40.25
34%
-183
- C1 -
-
2PZJ
1
?
A:
[30-82]
-------------------------------
L
A
N
T
N
V
M
V
V
G
G
A
G
F
V
G
S
N
L
V
K
R
L
L
E
L
-
G
V
N
Q
V
H
V
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
HHSearch
40.16
19%
-36
- C1 -
-
4TQG
1
?
A:
[2-290]
------------------------------
Q
I
N
D
K
T
I
M
I
F
G
G
S
G
S
L
G
N
R
L
I
E
T
Y
I
N
N
-
N
--
I
I
V
N
Y
S
R
D
E
S
K
H
W
S
M
E
--
L
K
Y
K
-
S
----
D
K
L
K
N
I
I
G
D
I
R
D
F
E
K
V
Q
Q
S
I
M
R
-
I
N
P
D
I
I
I
I
A
A
A
L
K
H
I
D
R
-
C
E
Y
--
E
I
N
---
E
C
L
D
T
N
I
K
G
L
Q
N
V
L
K
V
T
E
I
NRSN
L
S
--
N
L
K
A
V
C
F
V
S
T
D
K
A
C
----------------
S
P
V
N
S
Y
G
M
S
K
A
I
C
E
T
L
V
V
E
K
S
K
Y
I
K--
D
---
I
K
-----
Y
V
C
V
R
Y
G
N
V
L
N
---------------------------
F
T
L
T
H-
T
-
S
M
T
R
F
I
M
T
L
D
D
S
V
K
L
I
E
Y
A
I
I
N
G
-
N
S
G
E
I
V
I
P
K
L
N
S
M
---
Y
---
I
K
D
M
I
E
L
F
A
D
K
Y
--------------------------
P
I
V
I
T
G
-
L
-
R
S
G
E
R
M
Y
E
S
L
I
N
D
T
Q
S
M
K
T
V
P
K
G
D
Y
Y
H
I
L
P
T
Y
D
---------------------------------------------------
48
PsiBlast_CBE
39.93
34%
-182
- C1 -
-
2Q1U
1
?
B:
[30-78]
-------------------------------
L
A
N
T
N
V
M
V
V
G
G
A
G
F
V
G
S
N
L
V
K
R
L
L
E
L
-
G
V
N
Q
V
H
V
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
39.90
34%
-182
- C1 -
-
2Q1S
1
?
A:
[30-79]
-------------------------------
L
A
N
T
N
V
M
V
V
G
G
A
G
F
V
G
S
N
L
V
K
R
L
L
E
L
-
G
V
N
Q
V
H
V
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------