@TOME V2.3
(Mar 2018)
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-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VT48: (2017-12-11 )
MKEFLKAYVQTFKDIVSNSSAFTTLFLSVILYSFFYPTAYKAERAESIPIVIVDEEQSLLTSQVIGQTANSPHVKIVDVTANFLEAEQMVREQKADGILLLPSNLTQSLRRGETGGIGLYLSTTNFLKTKEIGLGLATSIEATLKEYIERFGQRTHFQPALSIHQMPLFNTLSGYGSYIFPAVASLIIHQTIVLGLAMLVASYREQHEKITPIRFAGIFASIFTIGCLGSFYLFGFTLWFNDYPHGGNFVGLLVAVPIFISCVIGLGMLIGSLLDILERAGHIIVFSSVPLFLLTGAAWPHQAMPEWLQWFAWCLPSTHAVQMFVQLNQMGVPLNVVAPKLIFLATIGVIFLITAYSRLKVSK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70.........80........----90..---......100.......110.......--120........130---------....-.-.---.-140.---......150..--..-...160......------.170-.......--180...-....190.......200.......210--------........220.-......230.......240...-....250.......260.......270.......280.......290..-..-...300.......310.-......320...-------....330..------------------------.--------------------------------....340.......350.......360.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
K
E
F
L
K
A
Y
V
Q
T
F
K
D
I
VSNS
S
A
F
T
T
L
F
L
S
V
I
L
Y
S
F
FYPTAYKAERAESI
P
I
V
I
VDE
E
Q
S
L
L
T
S
Q
V
I
GQTAN-SP
H
V
K
I
V
DV
T
A
N
F
L
E
A
E
Q
M
----
V
R
E
Q---KAD
G
I
L
L
L
P
S
N
L
T
Q
S
L
RRGETG
G
I
G
L
--
Y
-
L
STTN
F
L
K
T
K
EI---------GLG
L
-
A
-
T
---
S
-
I
E
A
T
---
L
K
E
Y
I
E
R
FGQR--TH-FQP
A
L
S
I
HQM
P
L
------
F
N
T
L
-
S
GYG
S
Y
I
--
F
P
A
V
A
S
-
L
I
I
H
Q
T
I
V
L
G
L
A
M
L
V
A
S
Y
R
E
Q
HEKIT---------
P
I
R
F
A
G
I
F
A
S
I
F
-
T
I
G
C
L
G
S
F
Y
L
F
G
F
T
L
W
FNDYPH-GGN
F
V
G
L
L
V
A
V
P
I
F
I
S
C
V
I
G
L
G
M
L
I
G
S
L
L
D
I
L
E
RAG
H
I
I
V
FSSV
P
L
F
L
L-TG-AAWP
H
Q
A
M
P
E
W
L
Q
W
F
A
W
-CLP
S
T
H
A
V
Q
M
F
V
-------
Q
L
N
QMGVP
L
------------------------
N
--------------------------------VVA
P
K
L
I
F
L
A
T
I
G
V
I
F
L
I
T
A
Y
S
R
LKVSK
29
Fugue
62.36
19%
-30
- C1 -
-
3CNI
-
?
A:
[11-155]
-----------------------------------------------
Q
K
V
A
I
V
R
E
D
T
G
T
I
A
E
L
A
E
K
A
L
G
N
M
V
---
D
I
V
Y
A
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S
D
L
K
E
A
E
E
A
----
V
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E
---
K
A
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E
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A
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--
V
-
W
Y
L
R
G
T
G
L
S
E
A
V
---------
S
T
G
T
-
I
-
S
---
S
-
L
I
E
S
---
L
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A
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F
L
L
N
--
D
P
-
K
K
A
Q
L
L
F
D
P
L
E
I
------
V
Q
H
T
-
Y
L
R
G
S
L
F
K
N
H
S
P
E
A
I
M
N
V
F
Y
S
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
59.23
15%
-162
- C1 -
-
5NJG
1
?
B:
[454-660]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
L
F
V
V
E
K
K
L
F
I
H
EYISGYYRV
S
S
Y
F
L
G
K
L
L
S
D
L
L
P
M
R
M
L
P
S
I
I
F
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Y
F
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L
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P
K
A
D
A
F
F
V
M
M
F
T
L
M
M
V
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
T
I
C
F
V
F
M
M
I
F
-
S
G
-
L
L
V
N
L
T
T
I
A
S
W
L
S
W
L
Q
Y
-
F
S
I
P
R
Y
G
F
T
A
L
Q
-------
H
N
E
F
L
G
Q
N
F
------------------------
C
PGLNATGNNPCNYATCTGEEYLVKQGIDLSPW
G
L
W
K
N
H
V
A
L
A
C
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
-
11
HHSearch
59.23
15%
-162
- C1 -
-
5NJ3
1
?
A:
[454-660]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
L
F
V
V
E
K
K
L
F
I
H
E
Y
I
S
GYYR
V
S
S
Y
F
L
G
K
L
L
S
D
L
L
P
M
R
M
L
P
S
I
I
F
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C
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Y
F
M
L
G
L
K
P
K
A
D
A
F
F
V
M
M
F
T
L
M
M
V
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
T
I
C
F
V
F
M
M
I
F
-
S
G
-
L
L
V
N
L
T
T
I
A
S
W
L
S
W
L
Q
Y
-
F
S
I
P
R
Y
G
F
T
A
L
Q
-------
H
N
E
F
L
G
Q
N
F
------------------------
C
PGLNATGNNPCNYATCT
G
E
E
Y
L
V
K
Q
GIDLS
P
W
G
L
W
K
N
H
V
A
L
A
C
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
-
13
HHSearch
52.10
11%
-169
- C1 -
-
5DO7
-
ABCG8_HUMAN
B:
[492-667]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
Y
F
F
A
K
I
L
G
E
L
-
P
E
H
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
L
A
N
L
R
P
G
L
Q
P
F
L
L
H
F
L
L
V
W
L
V
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
N
A
L
Y
N
S
F
Y
L
A
-
G
G
-
F
M
I
N
L
S
S
L
W
T
V
P
A
W
I
S
K
-
V
S
F
L
R
W
C
F
E
G
L
M
-------
K
I
Q
F
S
R
R
T
Y
K
M
P
L
G
NLTIAVSGD
K
I
L
S
V
M
ELDS
Y
--------------------------------
P
L
Y
A
I
Y
L
I
V
I
G
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
-
1
PsiBlast_PDB
51.65
27%
-62
- C1 -
-
3CNI
-
?
A:
[13-106]
-------------------------------------------------
V
A
I
V
R
E
D
T
G
T
I
A
E
--
L
A
E
K
A
L
-
G
N
M
V
D
I
V
Y
A
G
S
D
L
K
E
A
E
E
A
----
V
K
K
E
---
K
A
P
A
I
I
V
I
P
K
G
F
S
Q
S
L
E
S
G
E
K
A
R
L
E
I
V
W
Y
-
L
R
G
T
G
L
--
S
E
A
V
---------
S
T
G
T
-
I
-
S
---
S
-
L
I
E
S
---
L
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
50.88
15%
-107
- C1 -
-
5XJY
2
?
A:
[533-1115]
-------------------------------------------------------------------------------
P
I
A
T
E
V
W
L
I
N
K
S
M
E
L
L
D
E
R
---
K
F
W
A
G
I
V
F
T
G
I
T
P
G
S
I
E
L
P
H
H
V
K
Y
K
I
--
R
-
M
D
I
D
N
V
E
R
T
N
K
I
KDGYWDPGP
R
A
D
P
-
F
-
E
DMR
Y
-
V
W
G
G
F
A
Y
L
Q
D
V
V
E
Q
A
I
I
R
V
L
T
G
-
T
E
K
K
T
G
V
Y
M
Q
Q
M
PYPCYV
D
D
I
F
-
L
R
V
M
S
R
S
--
M
P
L
F
M
T
-
L
A
W
I
Y
S
V
-
A
V
I
I
K
G
I
V
Y
E
K
E
A
R
L
K
E
T
M
R
I
M
GLD
N
-
S
I
L
W
F
S
W
F
I
S
S
--
L
I
P
L
L
V
S
A
G
L
L
V
V
I
L
K
L
G
N
L
L
P
-
Y
S
D
P
S
V
V
F
V
F
L
S
V
F
A
V
V
T
I
L
Q
C
F
L
I
S
T
L
F
S
R
A
N
L
A
A
A
C
G
G
I
I
Y
F
T
L
Y
L
P
-
Y
V
L
C
V
A
W
Q
D
Y
V
G
F
T
L
K
I
F
A
S
L
L
S
P
V
A
F
G
F
G
C
E
Y
F
A
L
F
EEQ--------------------------------------------------------------------
G
F
N
L
T
T
S
V
S
M
M
L
F
D
T
F
L
Y
G
V
M
T
W
Y
I
-
18
HHSearch
50.65
28%
-87
- C1 -
-
3CNI
-
?
A:
[11-87]
-----------------------------------------------
Q
K
V
A
I
V
R
E
D
T
G
T
I
A
E
-
L
A
E
K
A
L
G
--
N
M
V
D
I
V
Y
A
G
S
D
L
K
E
A
E
E
A
----
V
K
K
E
---
K
A
P
A
I
I
V
I
P
K
G
F
S
Q
S
L
E
S
G
E
K
A
R
L
E
I
V
W
Y
-
L
R
G
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
50.33
11%
-172
- C1 -
-
5DO7
-
ABCG8_HUMAN
D:
[492-667]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
Y
F
F
A
K
I
L
G
E
L
-
P
E
H
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
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A
N
L
R
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L
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P
F
L
L
H
F
L
L
V
W
L
V
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
N
A
L
Y
N
S
F
Y
L
A
-
G
G
-
F
M
I
N
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S
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W
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V
P
A
W
I
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K
-
V
S
F
L
R
W
C
F
E
G
L
M
-------
K
I
Q
F
S
R
R
T
Y
K
M
P
L
GNL
T
I
A
V
S
GD
K
I
L
S
V
M
ELDS
Y
--------------------------------
P
L
Y
A
I
Y
L
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V
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G
L
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G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
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36
Fugue
49.06
15%
-14
- C1 -
-
5TPM
-
PDHR_ECOLI
A:
[1-155]
------------------------------------------------------------
S
N
A
D
L
L
E
T
R
H
-
A
L
E
G
I
A
A
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Y
A
A
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T
D
E
D
K
----
E
R
I
R
---
E
L
H
H
A
I
E
L
A
Q
Q
--
S
G
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D
A
E
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N
A
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--
Y
Q
I
A
V
T
E
A
A
H
N
V
V
L
---------
L
H
L
L
R
C
M
E
---
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N
---
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N
F
E
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L
Y
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--
R
E
M
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-
P
L
V
S
S
H
R
T
R
I
------
F
E
A
I
M
A
G
K
-------
P
E
E
A
R
-
E
A
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R
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L
A
F
I
E
E
I
L
L
D
R
S
R
E
E
S
R
R
E
R
---------
S
L
R
R
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
47.89
26%
-273
* C1 *
-
1T6O
-
B:
[1-19]
--------------------------------------------------------------------------------
Q
D
S
R
R
S
A
D
A
L
----
L
R
L
Q
---
A
M
A
G
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
44.21
10%
-177
- C1 -
-
5DO7
-
ABCG5_HUMAN
A:
[461-645]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
Q
M
M
L
A
Y
A
L
H
V
L
-
P
F
S
V
V
A
T
M
I
F
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S
V
C
Y
W
T
L
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L
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A
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A
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E
F
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N
P
N
I
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V
V
A
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V
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G
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G
-
F
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I
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P
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P
F
K
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Y
-
F
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F
Q
K
Y
C
S
E
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-------
V
N
E
F
Y
G
L
N
F
------------------------
T
CAFTQ
G
I
Q
F
I
E
K
TCPGATS-------------
R
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
-
16
HHSearch
42.71
10%
-180
- C1 -
-
5DO7
-
ABCG5_HUMAN
C:
[461-645]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
Q
M
M
L
A
Y
A
L
H
V
L
-
P
F
S
V
V
A
T
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C
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A
A
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A
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H
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E
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L
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G
I
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Q
N
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I
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N
S
V
V
A
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S
I
A
G
V
L
V
G
S
G
-
F
L
R
N
I
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E
M
P
I
P
F
K
I
I
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Y
-
F
T
F
Q
K
Y
C
S
E
I
L
V
-------
V
N
E
F
Y
G
L
N
F
------------------------
T
CGSMCAFTQ
G
I
Q
F
I
E
K
TCPGATS---------
R
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
-
2
PsiBlast_PDB
41.89
37%
-257
- C1 -
-
4IKH
-
?
A:
[15-46]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
P
A
Q
-
F
P
E
W
I
Q
L
Y
S
---
L
P
T
P
N
G
V
K
V
S
I
-------
M
L
E
E
I
G
L
P
--------------------------------------------------------------------------------------
4
PsiBlast_PDB
37.08
30%
56
- C2 -
-
2E3T
1
XDH_RAT
A:
[718-773]
------------------------------------------------------------------------------
D
L
K
K
G
F
S
E
A
D
N
V
----
V
S
G
E
L
Y
I
G
G
Q
E
H
F
Y
L
E
T
N
C
T
I
A
V
P
K
G
E
A
G
E
M
E
L
--
F
-
V
S
T
Q
N
T
M
K
T
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
35.80
30%
50
* C2 *
-
4YTY
1
XDH_RAT
A:
[718-773]
------------------------------------------------------------------------------
D
L
K
K
G
F
S
E
A
D
N
V
----
V
S
G
E
L
Y
I
G
G
Q
E
H
F
Y
L
E
T
N
C
T
I
A
V
P
K
G
E
A
G
E
M
E
L
--
F
-
V
S
T
Q
N
T
M
K
T
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
35.44
30%
58
- C2 -
-
1WYG
1
XDH_RAT
A:
[718-778]
------------------------------------------------------------------------------
D
L
K
K
G
F
S
E
A
D
N
V
----
V
S
G
E
L
Y
I
G
G
Q
E
H
F
Y
L
E
T
N
C
T
I
A
V
P
K
G
E
A
G
E
M
E
L
--
F
-
V
S
T
Q
N
T
M
K
T
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
35.26
30%
70
- C2 -
-
4YSW
1
XDH_RAT
A:
[718-773]
------------------------------------------------------------------------------
D
L
K
K
G
F
S
E
A
D
N
V
----
V
S
G
E
L
Y
I
G
G
Q
E
H
F
Y
L
E
T
N
C
T
I
A
V
P
K
G
E
A
G
E
M
E
L
--
F
-
V
S
T
Q
N
T
M
K
T
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
35.10
30%
65
- C2 -
-
3AN1
1
XDH_RAT
A:
[718-779]
------------------------------------------------------------------------------
D
L
K
K
G
F
S
E
A
D
N
V
----
V
S
G
E
L
Y
I
G
G
Q
E
H
F
Y
L
E
T
N
C
T
I
A
V
P
K
G
E
A
G
E
M
E
L
--
F
-
V
S
T
Q
N
T
M
K
T
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
35.07
30%
63
- C2 -
-
4YTZ
1
XDH_RAT
A:
[718-773]
------------------------------------------------------------------------------
D
L
K
K
G
F
S
E
A
D
N
V
----
V
S
G
E
L
Y
I
G
G
Q
E
H
F
Y
L
E
T
N
C
T
I
A
V
P
K
G
E
A
G
E
M
E
L
--
F
-
V
S
T
Q
N
T
M
K
T
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
34.31
15%
-266
- C1 -
-
5DO7
-
ABCG5_HUMAN
C:
[365-414]
F
S
K
L
G
V
L
L
R
R
V
T
R
N
L
V
R
N
K
L
A
V
I
T
R
L
L
Q
N
L
I
M
G
L
F
L
L
F
F
V
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------