@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTM9: (2017-12-14 )
MAALLGVNIDHVATLRQARGTAYPDPVEAALICEQAGAEGITLHLREDRRHIQDDDVRRMRPLLKTRMNLEMAVTDEMVEFAKEIQPQHVCFVPERRQEVTTEGGLDVVGNFEKVKAATQALAAIGCDVSLFIDADFAQIDAAIACGAPTIELHTGAYTDATTEQEQQEELARIVKGVEYAASKGLVVNAGHGLNLKNIAPIAAIPQIHALNIGHSIIAESVFVGLVQAVKDMKTAIQAAG
Atome Classification :
(30 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160------------....----.----------------.---.-----..170.......180..----.....190.......200.......210.......220.......230.......240
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
A
A
L
LGV
N
I
D
H
V
A
T
L
R
Q
ARGTAYPD
P
V
E
A
A
L
I
C
E
QAGAE
G
I
T
L
H
L
R
E
DRRHIQD
D
D
V
R
R
M
R
P
L
L
K
T
RMNL
E
M
AV
T
D
E
M
V
E
F
A
K
EIQPQ
H
V
C
FV
P
E
R
R
Q
EVTTEGGL
D
V
VG
N
F
E
K
V
K
A
A
T
Q
A
L
A
AIGC
D
V
S
L
F
I
DA
D
F
A
Q
I
D
A
AIACGA
P
T
I
E
L
HTGAYTD--------------AT
T
E
----
Q
----------------
E
---
Q
-----
Q
E
E
L
A
R
I
V
K
G
V
E
Y
AASK----
G
L
V
V
NAGHGLNLKNIAPIAAI
P
Q
I
H
A
LNI
G
H
S
I
I
A
E
S
V
F
V
G
L
V
Q
A
V
K
D
M
K
T
A
I
QAAG-
46
Fugue
97.63
61%
-141
- C6 -
-
1HO1
-
PDXJ_ECOLI
A:
[2-243]
A
E
L
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
-------
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
R
L
M
L
E
A
R
G
19
PsiBlast_CBE
96.49
65%
-144
- C6 -
-
3F4N
2
PDXJ_YERPE
B:
[8-244]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
I
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
I
Q
T
R
M
N
L
E
M
A
V
T
D
E
M
V
D
I
A
C
D
I
K
P
H
F
C
C
L
V
P
E
K
R
Q
----
E
G
G
L
D
V
A
G
Q
V
D
K
M
T
L
A
V
G
R
L
A
D
V
G
I
L
V
S
L
F
I
D
A
D
F
R
Q
I
D
A
A
V
A
A
G
A
P
Y
I
E
I
H
T
G
A
Y
A
D
--------------
A
S
T
V
----
L
----------------
E
---
R
-----
Q
A
E
L
M
R
I
A
K
A
A
T
Y
A
A
G
K
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
Q
P
I
A
A
L
P
E
M
H
E
L
N
I
G
H
A
I
I
G
Q
A
V
M
T
G
L
A
A
A
V
T
D
M
K
V
L
M
R
E
A
--
17
PsiBlast_CBE
95.19
65%
-137
- C6 -
-
3F4N
2
PDXJ_YERPE
D:
[8-244]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
I
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
I
Q
T
R
M
N
L
E
M
A
V
T
D
E
M
V
D
I
A
C
D
I
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
V
D
K
M
T
L
A
V
G
R
L
A
D
V
G
I
L
V
S
L
F
I
D
A
D
F
R
Q
I
D
A
A
V
A
A
G
A
P
Y
I
E
I
H
T
G
A
Y
A
D
--------------
A
S
T
V
----
L
----------------
E
---
R
-----
Q
A
E
L
M
R
I
A
K
A
A
T
Y
A
A
G
K
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
Q
P
I
A
A
L
P
E
M
H
E
L
N
I
G
H
A
I
I
G
Q
A
V
M
T
G
L
A
A
A
V
T
D
M
K
V
L
M
R
E
A
--
14
PsiBlast_CBE
94.58
65%
-143
- C6 -
-
3F4N
2
PDXJ_YERPE
G:
[8-244]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
I
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
I
Q
T
R
M
N
L
E
M
A
V
T
D
E
M
V
D
I
A
C
D
I
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
V
D
K
M
T
L
A
V
G
R
L
A
D
V
G
I
L
V
S
L
F
I
D
A
D
F
R
Q
I
D
A
A
V
A
A
G
A
P
Y
I
E
I
H
T
G
A
Y
A
D
--------------
A
S
T
V
----
L
----------------
E
---
R
-----
Q
A
E
L
M
R
I
A
K
A
A
T
Y
A
A
G
K
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
Q
P
I
A
A
L
P
E
M
H
E
L
N
I
G
H
A
I
I
G
Q
A
V
M
T
G
L
A
A
A
V
T
D
M
K
V
L
M
R
E
A
--
1
PsiBlast_PDB
94.51
65%
-140
- C6 -
-
3F4N
2
PDXJ_YERPE
A:
[8-244]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
I
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
I
Q
T
R
M
N
L
E
M
A
V
T
D
E
M
V
D
I
A
C
D
I
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
V
D
K
M
T
L
A
V
G
R
L
A
D
V
G
I
L
V
S
L
F
I
D
A
D
F
R
Q
I
D
A
A
V
A
A
G
A
P
Y
I
E
I
H
T
G
A
Y
A
D
--------------
A
S
T
V
----
L
----------------
E
---
R
-----
Q
A
E
L
M
R
I
A
K
A
A
T
Y
A
A
G
K
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
Q
P
I
A
A
L
P
E
M
H
E
L
N
I
G
H
A
I
I
G
Q
A
V
M
T
G
L
A
A
A
V
T
D
M
K
V
L
M
R
E
A
--
57
HHSearch
94.39
63%
-135
- C6 -
-
1IXN
2
PDXJ_ECOLI
C:
[2-240]
-
E
L
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
R
L
M
L
E
A
--
3
PsiBlast_PDB
94.28
64%
-138
- C6 -
-
1HO1
-
PDXJ_ECOLI
A:
[5-235]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
-------
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
16
PsiBlast_CBE
93.99
65%
-141
- C6 -
-
3F4N
2
PDXJ_YERPE
E:
[8-244]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
I
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
I
Q
T
R
M
N
L
E
M
A
V
T
D
E
M
V
D
I
A
C
D
I
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
V
D
K
M
T
L
A
V
G
R
L
A
D
V
G
I
L
V
S
L
F
I
D
A
D
F
R
Q
I
D
A
A
V
A
A
G
A
P
Y
I
E
I
H
T
G
A
Y
A
D
--------------
A
S
T
V
----
L
----------------
E
---
R
-----
Q
A
E
L
M
R
I
A
K
A
A
T
Y
A
A
G
K
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
Q
P
I
A
A
L
P
E
M
H
E
L
N
I
G
H
A
I
I
G
Q
A
V
M
T
G
L
A
A
A
V
T
D
M
K
V
L
M
R
E
A
--
15
PsiBlast_CBE
93.90
65%
-141
- C6 -
-
3F4N
2
PDXJ_YERPE
F:
[8-244]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
I
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
I
Q
T
R
M
N
L
E
M
A
V
T
D
E
M
V
D
I
A
C
D
I
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
V
D
K
M
T
L
A
V
G
R
L
A
D
V
G
I
L
V
S
L
F
I
D
A
D
F
R
Q
I
D
A
A
V
A
A
G
A
P
Y
I
E
I
H
T
G
A
Y
A
D
--------------
A
S
T
V
----
L
----------------
E
---
R
-----
Q
A
E
L
M
R
I
A
K
A
A
T
Y
A
A
G
K
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
Q
P
I
A
A
L
P
E
M
H
E
L
N
I
G
H
A
I
I
G
Q
A
V
M
T
G
L
A
A
A
V
T
D
M
K
V
L
M
R
E
A
--
6
PsiBlast_PDB
93.89
64%
-139
- C6 -
-
1IXO
1
PDXJ_ECOLI
A:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
-------
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
58
HHSearch
93.30
63%
-133
* C6 *
-
1M5W
2
PDXJ_ECOLI
B:
[3-241]
-
E
L
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
R
L
M
L
E
A
--
18
PsiBlast_CBE
93.30
65%
-141
- C6 -
-
3F4N
2
PDXJ_YERPE
C:
[8-244]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
I
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
I
Q
T
R
M
N
L
E
M
A
V
T
D
E
M
V
D
I
A
C
D
I
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
V
D
K
M
T
L
A
V
G
R
L
A
D
V
G
I
L
V
S
L
F
I
D
A
D
F
R
Q
I
D
A
A
V
A
A
G
A
P
Y
I
E
I
H
T
G
A
Y
A
D
--------------
A
S
T
V
----
L
----------------
E
---
R
-----
Q
A
E
L
M
R
I
A
K
A
A
T
Y
A
A
G
K
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
Q
P
I
A
A
L
P
E
M
H
E
L
N
I
G
H
A
I
I
G
Q
A
V
M
T
G
L
A
A
A
V
T
D
M
K
V
L
M
R
E
A
--
59
HHSearch
92.71
63%
-124
- C6 -
-
3GK0
1
PDXJ_BURP1
A:
[30-270]
A
A
I
D
L
G
V
N
I
D
H
V
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
R
A
A
L
A
A
E
D
A
G
A
D
A
I
T
L
H
L
R
E
D
R
R
H
I
V
D
A
D
V
R
T
L
R
P
R
V
K
T
R
M
N
L
E
C
A
V
T
P
E
M
L
D
I
A
C
E
I
R
P
H
D
A
C
L
V
P
E
K
R
S
E
L
T
T
E
G
G
L
D
V
V
G
H
F
D
A
V
R
A
A
C
K
Q
L
A
D
A
G
V
R
V
S
L
F
I
D
P
D
E
A
Q
I
R
A
A
H
E
T
G
A
P
V
I
E
L
H
T
G
R
Y
A
D
--------------
A
H
D
A
----
A
----------------
E
---
Q
-----
Q
R
E
F
E
R
I
A
T
G
V
D
A
G
I
A
L
----
G
L
K
V
N
A
G
H
G
L
H
Y
T
N
V
Q
A
I
A
A
L
P
G
I
A
E
L
N
I
G
H
A
I
V
A
H
A
V
F
V
G
W
D
N
A
V
R
E
M
K
A
I
M
V
A
A
R
-
28
PsiBlast_CBE
92.67
64%
-137
- C6 -
-
1IXO
1
PDXJ_ECOLI
B:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
-------
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
27
PsiBlast_CBE
92.65
64%
-140
- C6 -
-
1IXO
2
PDXJ_ECOLI
C:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
-------
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
40
PsiBlast_CBE
92.63
63%
-126
- C6 -
-
3GK0
1
PDXJ_BURP1
H:
[34-269]
----
L
G
V
N
I
D
H
V
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
R
A
A
L
A
A
E
D
A
G
A
D
A
I
T
L
H
L
R
E
D
R
R
H
I
V
D
A
D
V
R
T
L
R
P
R
V
K
T
R
M
N
L
E
C
A
V
T
P
E
M
L
D
I
A
C
E
I
R
P
H
D
A
C
L
V
P
E
K
R
S
E
L
T
T
E
G
G
L
D
V
V
G
H
F
D
A
V
R
A
A
C
K
Q
L
A
D
A
G
V
R
V
S
L
F
I
D
P
D
E
A
Q
I
R
A
A
H
E
T
G
A
P
V
I
E
L
H
T
G
R
Y
A
D
--------------
A
H
D
A
----
A
----------------
E
---
Q
-----
Q
R
E
F
E
R
I
A
T
G
V
D
A
G
I
A
L
----
G
L
K
V
N
A
G
H
G
L
H
Y
T
N
V
Q
A
I
A
A
L
P
G
I
A
E
L
N
I
G
H
A
I
V
A
H
A
V
F
V
G
W
D
N
A
V
R
E
M
K
A
I
M
V
A
A
--
56
HHSearch
92.61
61%
-119
- C6 -
-
5DLC
-
PDXJ_PSEAB
C:
[13-253]
T
R
I
L
L
G
V
N
I
D
H
V
A
T
L
R
Q
A
R
G
T
R
Y
P
D
P
V
K
A
A
L
D
A
E
E
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
Q
E
R
D
V
R
V
L
K
E
V
L
Q
T
R
M
N
F
E
M
G
V
T
E
E
M
L
A
F
A
E
E
I
R
P
A
H
S
C
L
V
P
E
R
R
E
E
L
T
T
E
G
G
L
D
V
A
G
Q
E
Q
R
I
R
D
A
V
R
R
L
A
A
V
G
S
E
V
S
L
F
I
D
P
D
P
R
Q
I
E
A
S
A
R
V
G
A
P
A
I
E
L
H
T
G
R
Y
A
D
--------------
A
E
D
P
----
E
----------------
E
---
Q
-----
A
R
E
L
Q
R
V
R
E
G
V
A
L
G
R
S
L
----
G
L
I
V
N
A
G
H
G
L
H
Y
H
N
V
E
P
V
A
A
I
D
G
I
N
E
L
N
I
G
H
A
I
V
A
H
A
L
F
V
G
F
R
Q
A
V
A
E
M
K
A
L
M
L
A
A
A
-
7
PsiBlast_PDB
92.36
64%
-128
- C6 -
-
1IXP
-
PDXJ_ECOLI
A:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
26
PsiBlast_CBE
92.31
64%
-137
- C6 -
-
1IXO
1
PDXJ_ECOLI
D:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
-------
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
13
PsiBlast_CBE
92.17
65%
-133
- C6 -
-
3F4N
2
PDXJ_YERPE
H:
[8-244]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
I
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
I
Q
T
R
M
N
L
E
M
A
V
T
D
E
M
V
D
I
A
C
D
I
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
V
D
K
M
T
L
A
V
G
R
L
A
D
V
G
I
L
V
S
L
F
I
D
A
D
F
R
Q
I
D
A
A
V
A
A
G
A
P
Y
I
E
I
H
T
G
A
Y
A
D
--------------
A
S
T
V
----
L
----------------
E
---
R
-----
Q
A
E
L
M
R
I
A
K
A
A
T
Y
A
A
G
K
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
Q
P
I
A
A
L
P
E
M
H
E
L
N
I
G
H
A
I
I
G
Q
A
V
M
T
G
L
A
A
A
V
T
D
M
K
V
L
M
R
E
A
--
5
PsiBlast_PDB
91.93
64%
-131
- C6 -
-
1IXN
2
PDXJ_ECOLI
A:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
30
PsiBlast_CBE
91.30
64%
-131
- C6 -
-
1IXN
2
PDXJ_ECOLI
C:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
29
PsiBlast_CBE
91.21
64%
-128
- C6 -
-
1IXN
2
PDXJ_ECOLI
D:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
31
PsiBlast_CBE
91.14
64%
-130
- C6 -
-
1IXN
2
PDXJ_ECOLI
B:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
4
PsiBlast_PDB
91.02
64%
-129
- C6 -
-
1HO4
1
PDXJ_ECOLI
A:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
34
PsiBlast_CBE
90.79
64%
-128
- C6 -
-
1HO4
1
PDXJ_ECOLI
B:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
33
PsiBlast_CBE
90.79
64%
-130
- C6 -
-
1HO4
1
PDXJ_ECOLI
C:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
32
PsiBlast_CBE
90.51
64%
-129
- C6 -
-
1HO4
1
PDXJ_ECOLI
D:
[4-234]
---
L
L
G
V
N
I
D
H
I
A
T
L
R
N
A
R
G
T
A
Y
P
D
P
V
Q
A
A
F
I
A
E
Q
A
G
A
D
G
I
T
V
H
L
R
E
D
R
R
H
I
T
D
R
D
V
R
I
L
R
Q
T
L
D
T
R
M
N
L
E
M
A
V
T
E
E
M
L
A
I
A
V
E
T
K
P
H
F
C
C
L
V
P
E
K
R
Q
E
V
T
T
E
G
G
L
D
V
A
G
Q
R
D
K
M
R
D
A
C
K
R
L
A
D
A
G
I
Q
V
S
L
F
I
D
A
D
E
E
Q
I
K
A
A
A
E
V
G
A
P
F
I
E
I
H
T
G
C
Y
A
D
--------------
A
K
T
D
----
A
----------------
E
---
Q
-----
A
Q
E
L
A
R
I
A
K
A
A
T
F
A
A
S
L
----
G
L
K
V
N
A
G
H
G
L
T
Y
H
N
V
K
A
I
A
A
I
P
E
M
H
E
L
N
I
G
H
A
I
I
G
R
A
V
M
T
G
L
K
D
A
V
A
E
M
K
--------
12
PsiBlast_PDB
77.38
42%
-68
- C6 -
-
3O6D
1
PDXJ_CAMJE
A:
[3-259]
-
A
M
L
L
G
V
N
I
D
H
I
A
V
L
R
Q
A
R
M
V
N
D
P
D
L
L
E
A
A
F
I
V
A
R
H
G
-
D
Q
I
T
L
H
V
R
E
D
R
R
H
A
Q
D
F
D
L
E
N
I
I
K
F
C
K
S
P
V
N
L
E
C
A
L
N
D
E
I
L
N
L
A
L
K
L
K
P
H
R
V
T
L
V
P
E
K
R
E
E
L
T
T
E
G
G
L
C
L
--
N
H
A
K
L
K
Q
S
I
E
K
L
Q
N
A
N
I
E
V
S
L
F
I
N
P
S
L
E
D
I
E
K
S
K
I
L
K
A
Q
F
I
E
L
H
T
G
H
Y
A
N
L
H
N
A
L
FSNISHTAF
A
L
K
E
----
L
----------------
D
---
Q
D
K
K
T
L
Q
A
Q
F
E
K
E
L
Q
N
L
E
L
C
A
K
K
G
L
E
L
G
L
K
V
A
A
G
H
G
L
N
Y
K
N
V
K
P
V
V
K
I
K
E
I
C
E
L
N
I
G
Q
S
I
V
A
R
S
V
F
T
G
L
Q
N
A
I
L
E
M
K
E
L
I
K
----
60
HHSearch
77.13
44%
-67
- C6 -
-
3O6D
1
PDXJ_CAMJE
A:
[2-260]
N
A
M
L
L
G
V
N
I
D
H
I
A
V
L
R
Q
A
R
M
V
N
D
P
D
L
L
E
A
A
F
I
V
A
R
H
G
-
D
Q
I
T
L
H
V
R
E
D
R
R
H
A
Q
D
F
D
L
E
N
I
I
K
F
C
K
S
P
V
N
L
E
C
A
L
N
D
E
I
L
N
L
A
L
K
L
K
P
H
R
V
T
L
V
P
E
K
R
E
E
L
T
T
E
G
G
L
C
L
N
H
A
--
K
L
K
Q
S
I
E
K
L
Q
N
A
N
I
E
V
S
L
F
I
N
P
S
L
E
D
I
E
K
S
K
I
L
K
A
Q
F
I
E
L
H
T
G
H
Y
A
N
--------------
L
H
N
A
L
FSN
I
SHTAFALKELDQD
K
K
T
L
Q
A
Q
F
-----
E
K
E
L
Q
N
L
E
L
C
A
K
K
G
L
E
L
----
G
L
K
V
A
A
G
H
G
L
N
Y
K
N
V
K
P
V
V
K
I
K
E
I
C
E
L
N
I
G
Q
S
I
V
A
R
S
V
F
T
G
L
Q
N
A
I
L
E
M
K
E
L
I
K
R
---