@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VVC8: (2017-12-23 )
MITANKGEWSEVYALFKLLSEGKLYAGDKDLNKIPNLIYPIISILRQESQDLLTYSPEPNHGVVHIQNGTSTFTISQSDFKGITELLLTEIKKKQPTASFSIPEVETFISQYNSKKIKAKSSAKSDIRIIIYDQKIGTTPELGFSIKSKLGKASTLLNASQATNFVYKVKNLTLSPQEIDDFNQLEFTVPIIQGRIHHLESLGGSVEFSHITNDVFNNNLILLDSLLPNIISEALYKYYTSPITSVKEIFEQVASANPIHYSLQHQHPFYEYKVKKLLCEIAIGMMPSTVWTGNNIDATGGYLVIKEDGDVICYHLYHRHEFEEYLYNNTRFEAASKSRHNYGNLFIENGELYMTLNLQIRFK
Atome Classification :
(20 SA)
---------------...----......10...--------..-----------...20--.-.......30........40--------.....-------------------------.-..50.......---.60-------------------.......--.70---.-..----.....------------------80.......-.90.........100.--------------------.-.-----....--110------......---------------..---------------120---------........----130-..----.....140........----150.......-160.....----..170.....-..---------180-----.......190.......-------..200..-.....210.......220-........230....--------.---------------..240.-----------......250---.......--------------------------.260---........270--.......280------.------.-----......290.......300----------..-......310-........320...----...------.330-........340-------......---..350-----.........360.--------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------MIT----ANKG
E
W
S
E
V
Y
A
--------
L
F
-----------
K
L
L
SE--G-
K
L
YAGD
K
D
L
N
KI
P
N
L
I
Y
P
I
--------
I
S
I
L
R
-------------------------Q-ESQ
D
L
L
T
YSPE---PNH-------------------
G
V
V
H
IQN--GT
S
---
T
-
F
T
----IS
Q
S
D
------------------
F
K
G
I
T
E
L
L
L
-
T
E
-
I
K
KKQPTASFS
I
P
--------------------
E
-
V
-----
E
T
F
I
--
S
Q-------YNSK
K
I
---------------KA---------------KS----------SAKS
D
I
R
I
----
I
I
Y
-DQ----KIGTTPE-L
G
F
S
I
K
S
K----LGK
A
S
T
L
L
N
A
-
S
QAT
N
F
V
Y
----
K
VKNLTL
S
P
Q
-EI---------DDF-----NQ
L
E
F
T
V
P
--
I
I
Q
G
R
I
H
-------
H
L
E
S
LGG-
S
V
E
F
S
H
I
T
N
D
VFNN
N
L
-
I
-
L
L
D
S
L
L
P
N
I
I
S
E
A
L
Y
--------
K
---------------
Y
YTS
P
I
-----------
T
S
V
K
E
I
F
E
----
Q
V
ASANP--------------------------
I
H
Y
----
S
LQHQH
P
F
Y
E
Y
--
K
V
K
K
L
L
C
E
I
-------
A
------I-----GMMPS
T
V
WTGNNIDATG
G
-----------
Y
L
-
V
I
KEDG
D
V
--
I
C
Y
H
L
Y
H
R
H
E
F
E
E
Y
----
L
YN------NT
R
--
F
EAASKSRHN--------YG
N
L
F
I
---ENG-------
E
L
Y
M
T
L
N
L
Q
I
R
FK--------
20
Fugue
64.47
19%
13
- C7 -
-
5IHE
1
DP2S_PYRAB
A:
[8-475]
---------------
V
V
L
----
D
K
Y
G
Y
P
I
L
Y
Y
S
--------
K
Y
ED
V
V
I
E
W
NPS
V
T
P
V
Q
I
--
E
-
K
N
Y
E
V
K
F
D
V
R
Q
V
V
E
A
Y
A
S
L
--------
F
K
S
R
L
-------------------------
S
-
K
L
K
R
I
L
R
E
N
P
E
---
I
S
N
VVDIGKLNYVSGD
E
E
V
T
I
I
G
L
V
N
S
K
R
--
E
T
N
---
R
G
L
I
----
F
E
V
E
D
------------------
K
T
G
I
V
K
V
F
L
-
P
K
-
D
S
E
D
Y
R
E
A
F
K
V
L
P
--------------------
D
A
V
-----
V
A
F
K
--
G
F
-------
Y
S
K
K
G
I
FFAN
K
F
Y
L
PDVPL
Y
R
K
Q
---------------
K
P
----------
P
L
E
E
K
V
Y
A
----
I
L
I
S
D
I
----
H
V
G
S
R
E
F
-
C
E
K
A
F
L
K
F
----
L
E
W
L
N
G
H
V
E
S
-
K
E
E
E
E
I
V
S
----
R
V
K
Y
L
I
I
A
G
D
-
V
V
---------
D
G
I
GIYPG
Q
Y
S
D
L
V
I
P
--
D
I
F
D
Q
Y
E
-------
A
L
A
N
L
L
A
-
N
V
P
-
E
H
I
T
M
F
I
G
P
G
N
H
-----
D
A
A
R
P
A
I
P
Q
P
E
F
Y
--------
K
---------------
E
Y
A
K
P
I
-----------
Y
K
L
K
N
-------
A
I
I
I
S
N
P
--------------------------
A
V
I
----
R
L
H
G
R
D
F
L
I
A
H
G
R
G
I
E
D
V
V
S
F
V
-------
P
GLTHHK
P
-----
G
L
P
M
V
E
L
L
K
M
R
H
L
A
P
T
F
G
GKVPIAPDPED
L
L
-
V
I
E
E
V
P
D
L
--
V
Q
M
G
H
V
H
V
Y
D
A
V
V
Y
RG
V
Q
L
V
N
SATWQA
Q
T
E
--
F
Q
K
M
V
N
I
V
P
T
--------
P
A
K
V
P
V
V
DV
E
S
A
-------
R
V
V
K
V
L
D
F
S
G
W
C
---------
27
Fugue
59.37
17%
-
- C3 -
-
4Y25
-
PGAA_ECOLI
A:
[513-808]
-----------------------------
D
V
H
N
--------
L
A
-----------
E
L
R
I
A
--
G
-
S
T
G
I
D
A
E
G
P
D
S
G
K
H
-------------------------------------------
D
-
V
D
L
T
T
I
V
Y
S
P
P
-----------------------------
L
K
D
--
N
W
R
---
G
-
F
A
----
G
F
G
Y
A
------------------
D
G
G
I
V
R
D
W
L
-
A
G
-
V
E
W
R
S
R
-----------------------------------
N
I
W
L
--
E
A
-------
E
Y
A
E
R
V
---------------
F
N
---------------
H
E
----------
H
K
P
G
A
R
L
S
----
G
W
Y
-
D
F
NDN
W
R
I
G
S
Q
L
E
R
L
S
H
R
V
P
L
R
----
A
M
K
N
G
V
T
G
N
S
-
A
Q
A
Y
V
R
W
Y
QNER
R
K
Y
G
V
S
W
A
F
T
-
D
F
---------
S
D
S
-----
N
Q
R
H
E
V
S
L
--
E
G
Q
E
R
I
W
-------
S
S
----------
P
Y
L
I
V
D
F
---------
L
P
S
L
Y
Y
E
Q
N
T
E
H
D
T
--------
P
---------------
Y
Y
N
-
P
I
-----------
K
T
F
D
I
V
-----------------------------------------
P
----
A
F
E
A
S
H
L
L
W
R
S
--
Y
--------------------------------
E
N
S
W
E
Q
I
F
S
A
G
V
G
A
-----------
S
W
-
Q
K
H
Y
G
T
D
V
--
V
T
Q
L
G
Y
G
Q
R
I
S
W
N
D
----
V
I
D
------
A
G
A
--
T
L
R
W
E
K
R
P
Y
D
--------
G
D
-------
R
E
H
-------
N
L
Y
V
E
F
D
M
T
F
R
F
R
--------
19
Fugue
52.41
16%
31
- C7 -
-
4K7J
3
?
A:
[26-375]
--------------G
L
L
T
DYGN
A
S
A
S
P
W
M
K
K
L
Q
S
V
A
Q
GSG
E
T
F
-----------
R
I
L
Q
I
--
G
D
S
H
T
A
G
D
F
F
T
D
S
L
R
K
R
L
Q
K
T
WGDGGIGW
V
Y
P
A
N
-------------------------
V
-
K
G
Q
R
M
A
A
V
R
H
N
---
G
N
W
-------------------
Q
S
L
T
S
R
N
--
N
T
G
---
D
-
F
P
LGG
I
L
A
H
T
G
------------------
S
G
G
S
M
T
L
T
A
-
S
D
G
I
A
S
K
Q
R
V
S
L
F
A
K
P
--------------------
L
-
L
-----
A
E
Q
T
--
L
T
-------
V
N
G
N
T
V
---------------
S
A
---------------
N
G
----------
G
G
W
--------------
Q
----
V
L
D
T
G
A
A
-
L
P
L
T
I
H
T
E
----
M
P
W
D
I
G
F
I
N
I
-
E
N
P
A
G
G
I
T
-----
V
S
A
M
G
I
N
G
A
-
Q
L
---------
T
Q
W
-----
S
K
W
R
--------
A
D
R
M
N
-------
D
L
A
Q
T
G
A
D
L
V
I
L
S
Y
G
T
N
E
A
F
N
N
N
I
---------------
D
I
A
--------
D
---------------
T
E
Q
K
W
L
-----------
D
T
V
R
Q
I
R
D
----
S
L
P
A
A
G
I
--------------------------
L
I
I
G
A
PE
S
L
K
N
T
L
G
-----------
V
C
G
T
-------
R
------
P
-----
V
R
L
T
E
V
Q
Q
M
Q
R
R
V
A
R
Q
G
Q
-----------
T
M
-
F
W
S
W
Q
N
A
M
GG
I
C
S
---------------
M
K
N
------
W
L
N
--
Q
G
W
A
A
K
D
G
V
H
--------
F
S
A
K
G
Y
---
R
R
A
-------
A
E
M
L
A
D
S
L
E
E
L
V
R
S
A------
21
Fugue
47.99
18%
10
- C7 -
-
5E7G
12
Y2650_BACO1
A:
[1-456]
-----D
A
I
P
V
I
HYIR
V
T
D
----
V
N
P
G
T
M
I
V
V
V
G
--------
E
------------
H
L
G
G
T
--
Q
-
K
V
Y
I
N
D
Q
E
V
S
F
N
R
N
Y
V
T
S
T
--------
S
I
I
L
T
VPNELELTGQNPELKG
E
I
R
I
E
T
E
H
G
V
-
A
A
Y
N
M
H
V
L
S
P
A
---
P
Y
I
-------------------
T
R
I
S
A
T
Y
--
P
I
K
PG
D
Q
-
M
T
----
V
I
G
G
N
------------------
F
Y
E
V
Q
A
V
Y
L
S
T
E
-
Q
P
A
K
D
G
T
R
P
V
D
V
Q
--------------------
E
-
I
-----
T
N
Y
E
V
N
N
K
-------
Y
S
Q
I
T
L
---------------
T
A
P
A
NLLE
E
G
Y
L
V
V
E
C
Y
T
S
----------
S
A
V
T
E
F
K
K
NGPK
P
V
V
-
T
A
----
V
S
S
T
M
P
V
-
V
G
S
T
V
T
I
T
G
Q
NF
I
E
V
S
R
V
N
I
N
A
-
E
----
F
D
I
----
P
V
G
D
I
T
T
S
--------------
N
T
F
-----
D
E
I
S
F
V
L
P
QA
P
T
Q
S
G
H
I
-------
S
V
T
A
I
G
G
-
T
V
E
S
A
E
I
F
Y
-
P
L
E
N
V
I
-
L
-
N
Y
D
G
I
G
S
H
V
W
G
D
C
S
F
--------
V
VADGSSAPYVSNG
T
C
L
G
I
T
G
T
-----------
V
S
A
S
N
Y
W
W
----
K
Q
S
Y
S
N
A
--------------------------
Q
W
V
----
N
T
S
I
I
P
G
N
I
P
I
--
D
D
L
K
L
Q
F
E
C
-------
F
------
V
K
E
V
F
T
G
P
V
F
Q
I
A
M
C
E
N
F
D
A
A
L
N
G
-----------
Y
V
P
V
S
S
F
T
G
K
T
--
E
T
G
K
W
M
Q
C
S
V
S
L
S
S
----
V
V
A
------
D
A
T
--
Y
Q
D
F
L
N
R
N
S
T
--------
H
I
G
V
Y
A
---
T
N
P
GS
S
Q
A
T
I
E
V
Y
F
D
-
N
F
R
I
V
R
K
--------
25
Fugue
39.54
16%
22
- C5 -
-
5MB9
1
?
A:
[23-578]
G
E
R
V
V
I
G
I
T
F
G
NS
N
S
S
I
A
----
H
T
V
D
D
K
A
E
V
I
A
N
EDGDRQ-
I
P
-----------
T
I
L
S
Y
V
D
G
-
D
E
Y
Y
G
Q
Q
A
K
N
F
L
V
R
N
P
K
N
T
--------
V
A
Y
F
R
-------------------------
D
I
L
G
Q
D
F
K
S
V
D
P
T
---
H
N
H
-------------------
A
S
A
H
P
Q
E
AG
D
N
V
---
V
-
F
T
----
I
K
D
K
A
EEDAEPSTLT
V
S
E
I
A
T
R
Y
L
R
R
L
V
G
A
A
S
-
E
Y
-
L
G
K
K
V
T
S
A
V
I
T
I
P
TNFT
E
K
Q
K
A
A
L
I
A
A
A
A
A
A
DL
E
-
V
-----
L
Q
L
I
--
S
E
P
A
A
A
V
L
A
Y
D
A
R
P
E
---------------
A
T
---------------
I
S
D
K
I
I
V
V
A
D
L
G
G
S
R
S
D
V
T
V
----
L
A
S
-
R
S
----
G
M
Y
T
I
L
A
-
T
V
H
D
Y
E
Y
H
----
G
I
A
L
D
K
V
L
I
D
-
H
F
S
K
E
F
L
K
----
K
N
P
G
A
K
D
P
R
E
-
N
P
---------
R
S
L
-----
A
K
L
R
L
E
A
E
--
S
T
K
R
A
L
S
R
ST
N
A
S
F
S
V
E
S
L
I
D
-
G
L
D
F
A
S
T
I
N
R
L
R
Y
E
T
I
A
R
-
T
V
F
E
G
F
N
R
L
V
E
S
A
V
K
--------
K
---------------
A
G
L
D
P
L
DVD
E
V
I
M
S
G
GT
S
N
T
P
R
I
A
A
----
N
F
R
Y
I
F
P
ES
T
R
I
L
A
PSTDPSALNPSE
L
Q
A
R
G
A
A
L
Q
A
----
S
L
I
Q
E
F
E
T
E
D
I
--
E
Q
S
T
H
A
A
V
T
T
M
P
H
V
T
N
A
------
I
-----
G
V
V
S
V
S
K
F
V
P
I
I
A
P
E
T
A
V
-----------
P
A
-
R
R
T
V
H
G
G
D
--
V
L
V
K
V
V
E
G
S
T
H
I
N
V
----
I
K
R
------
E
K
V
--
W
K
I
G
S
T
L
A
E
A
--------
A
V
R
G
V
K
---
K
G
A
-------
K
V
E
V
T
I
N
V
N
T
D
L
T
V
I
V
T
A
R
E
V
17
HHSearch
35.92
22%
-268
- C6 -
-
3T1X
-
?
A:
[30-47]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Y
-----------
A
L
-
L
I
D
R
K
G
F
V
--
L
A
H
K
E
A
------------------------------------------------------------------------------------
23
Fugue
35.67
17%
13
- C5 -
-
4ART
2
Y273_ATV
A:
[22-270]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
----
D
A
T
N
D
------------------
E
E
K
L
A
D
I
V
E
-
N
E
-
I
E
K
E
I
R
K
I
E
N
F
Y
Y
--------------------
Y
-
I
L
RDG
K
I
Y
P
A
--
S
D
-------
Y
D
I
E
V
E
---------------
K
G
---------------
K
R
----------
S
-
A
N
D
I
Y
A
----
F
V
E
-
T
D
----
V
T
R
D
F
D
E
-
F
L
F
D
I
D
Y
G
----
L
P
S
I
S
D
I
L
K
F
-
Y
L
E
K
A
G
-
F
----
R
I
A
N
E
V
P
T
P
N
--
L
---------
K
Y
Y
-----
I
H
A
V
V
E
F
P
Q-
Y
L
A
V
N
I
Y
-------
D
I
D
S
L
A
R
-
A
L
R
I
P
Q
I
V
E
Q
K
L
G
N
K
----------
P
R
T
I
T
A
D
E
F
--------
N
---------------
D
I
E
R
I
V
-----------
A
E
E
Q
P
I
L
A
GYT
Y
D
E
A
L
R
I
P
--------------------------
Y
H
Y
----
Y
V
D
H
N
---
N
S
F
--
K
D
D
A
L
K
I
A
H
-------
A
------
Y
-----
L
Q
L
F
P
T
P
Y
Q
V
C
Y
E
W
K
A
R
W
-----------
F
N
-
K
I
D
--------
C
L
K
L
E
R
L
K
---------------------------------------------------------------------------------
28
Fugue
31.10
15%
11
- C4 -
-
2W0C
-
SPIKE_BPPM2
L:
[1-335]
---------------
M
I
V
----
K
K
K
-------------------------------
L
A
A
--
G
-
E
F
A
E
T
F
K
N
G
N
N
I
T
I
---------------
I
K
A
-------------------------
V
-
G
E
L
V
L
R
A
Y
G
A
D
---
G
G
E
-------------------
G
L
R
T
I
V
R
--
Q
G
V
---
S
-
I
K
----
G
M
N
Y
T
------------------
S
V
M
L
H
T
E
Y
A
-
Q
E
-
I
E
Y
W
V
G
D
L
D
Y
S
F
Q
--------------------
E
-
Q
-----
T
T
K
S
--
R
D
-------
V
N
S
F
Q
I
---------------
P
L
---------------
R
D
----------
G
----
V
R
E
----
L
L
P
-
E
D
----
A
----
S
R
-
N
R
A
S
I
K
S
P
----
V
D
I
W
I
G
G
E
N
M
-
T
A
L
N
G
I
V
D
----
G
G
R
K
F
E
A
G
Q
E
F
Q
I
---------
N
T
F
-----
G
S
V
N
Y
W
V
S
--
D
E
E
I
R
V
F
-------
K
E
Y
S
A
R
A
-
K
Y
A
Q
N
E
G
R
T
A
L
E
A
N
N
V
-
P
-
F
F
D
I
D
V
P
P
E
L
D
G
V
P
------------------------------------------------
F
S
----
L
K
A
R
V
R
H
--------------------------
K
S
K
----
G
V
D
G
L
G
D
Y
T
S
I
--
S
V
K
P
A
F
Y
I
T
-------
E
------
G
-----
D
E
T
T
D
T
L
I
K
Y
T
S
Y
G
S
T
G
S
-----------
H
S
-
G
Y
D
F
D
D
N
T
--
L
D
V
M
V
T
L
S
A
G
V
H
R
V
----
F
P
V
------
E
T
E
LD
Y
D
A
V
Q
E
V
Q
H
D
WYDESFTT
F
I
E
V
Y
S
---
D
D
P
-------
L
L
T
V
K
G
Y
A
Q
I
L
M
E
RT------
7
PsiBlast_PDB
28.04
40%
-19
- C6 -
-
5TPN
-
?
A:
[127-173]
-----------------------------------------------------------------------------------------------------------------------------------------
N
K
-------------------
A
V
V
S
L
S
N
--
G
V
S
---
V
-
L
T
----
S
K
V
L
D
------------------
L
K
N
Y
I
D
K
Q
L
-
L
P
-
I
V
N
K
Q
---
S
C
S
I
P
--------------------
N
-
I
-----
E
T
V
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
26.99
17%
-
- C1 -
-
1MKC
-
A:
[66-71]
------------------------
F
E
N
W
G
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
26.43
22%
-175
- C8 -
-
2JD3
-
?
A:
[50-85]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
H
-
Q
L
D
P
R
L
P
V
L
L
T
A
I
L
----------------------------
S
E
E
-----------
F
S
A
D
Q
V
V
T
----
L
L
S
Q
T
T
G
--------------------------
W
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
26.37
28%
-71
- C8 -
-
1TVP
-
?
A:
[48-120]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
E
F
N
A
T
--
L
I
R
A
A
I
G
-------
H
G
T
S
T
G
G
-
S
L
N
F
D
------
W
E
G
N
M
-
S
-
R
L
D
T
V
V
N
A
A
I
A
E
D
M
Y
V
I
IDFHSH
E
---------------
A
H
T
D
Q
A
-----------
T
A
V
R
-
F
F
E
----
D
V
A
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
26.21
40%
-40
- C6 -
-
5C69
-
FUS_HRSVA
A:
[123-169]
-----------------------------------------------------------------------------------------------------------------------------------------
N
K
-------------------
A
V
V
S
L
S
N
--
G
V
S
---
V
-
L
T
----
S
K
V
L
D
------------------
L
K
N
Y
I
D
K
Q
L
-
L
P
-
I
V
N
K
Q
---
S
C
S
I
P
--------------------
N
-
I
-----
E
T
V
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
26.20
40%
-48
- C6 -
-
5K6I
1
FUS_HRSVA
F:
[111-157]
-----------------------------------------------------------------------------------------------------------------------------------------
N
K
-------------------
A
V
V
S
L
S
N
--
G
V
S
---
V
-
L
T
----
F
K
V
L
D
------------------
L
K
N
Y
I
D
K
Q
L
-
L
P
-
I
L
N
K
Q
---
S
C
S
I
P
--------------------
N
-
I
-----
E
T
V
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
26.14
35%
-134
* C8 *
-
4LGD
-
RASF5_HUMAN
G:
[6-22]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
F
S
I
P
--------------------
E
-
L
-----
Q
N
F
L
--
T
I
-------
L
E
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
25.94
28%
-74
- C- -
-
1TVN
-
?
A:
[48-120]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
E
F
N
A
T
--
L
I
R
A
A
I
G
-------
H
G
T
S
T
G
G
-
S
L
N
F
D
------
W
E
G
N
M
-
S
-
R
L
D
T
V
V
N
A
A
I
A
E
D
M
Y
V
I
IDFHSH
E
---------------
A
H
T
D
Q
A
-----------
T
A
V
R
-
F
F
E
----
D
V
A
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
25.44
40%
-28
- C6 -
-
5C6B
-
?
F:
[128-174]
-----------------------------------------------------------------------------------------------------------------------------------------
N
K
-------------------
A
V
V
S
L
S
N
--
G
V
S
---
V
-
L
T
----
S
K
V
L
D
------------------
L
K
N
Y
I
D
K
Q
L
-
L
P
-
I
V
N
K
Q
---
S
C
S
I
P
--------------------
N
-
I
-----
E
T
V
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
25.30
35%
-118
- C8 -
-
4OH8
-
B:
[5-21]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
F
S
I
P
--------------------
E
-
L
-----
Q
N
F
L
--
T
I
-------
L
E
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
24.77
20%
60
- C7 -
-
2N2T
-
?
A:
[1-84]
--------------------------------------------------------------------------
M
G
Q
W
Q
I
K
I
--------
Y
S
E
N
E
-------------------------
R
-
E
F
R
E
L
I
E
R
L
E
E
ERP
S
V
Q
-------------------
Y
T
E
T
T
R
N
--
G
R
R
---
Q
-
L
T
----
I
R
S
N
D
-------------------
K
N
E
V
D
R
I
L
-
E
E
-
V
R
R
K
V
P
N
A
R
V
R
E
T
--------------------
E
-
T
-----
G
S
L
E
--
H
H
-------
H
H
H
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
24.38
27%
-4
- C8 -
-
3RY7
1
?
A:
[91-186]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
K
----
T
G
Q
A
F
I
T
V
N
A
E
G
Q
N
T
I
Y
V
Y
----
G
G
A
N
M
T
M
T
P
E
-
D
V
I
N
A
K
D
A
I
I
N
A
D
F
V
V
---
A
Q
L
E
V
P
I
P
--
A
I
I
S
A
F
E
-------
I
A
K
A
H
G
V
-
T
T
V
L
N
P
A
P
A
K
A
L
P
N
E
L
-
L
S
L
I
D
I
I
V
P
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------