@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TYQ2: (2017-12-15 )
MCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNS
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20----.-----------------........30...-.-....--40--........50.-----.-----.-----.....60........---70........80........90......------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
C
R
I
LGLSRQS
Y
Y
YQSKPKK-----
D
-----------------
E
S
E
L
E
E
V
V
A
E
E
F
I
-
R
-
S
R
K
A--Y
G
--
S
R
K
I
K
K
A
L
S
KR-----G-----
I
-----
Q
I
S
R
R
K
I
S
R
I
M
K
NRG---LKSS
Y
T
V
A
Y
F
K
V
HHSTCNEAKTTNVLNS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
78
Fugue
62.21
29%
96
- C2 -
-
3V97
6
RLMKL_ECOLI
A:
[1-703]
A
M
N
S
L
F
A
S
T
A
RGL
E
E
L
L
K
T
E
L
E
N
L
GAVE
C
Q
V
V
QG
G
V
H
F
K
G
D
T
R
L
V
Y
Q
S
L
M
W
SRLAS
R
I
M
L
P
L
G
E
C
K
V
YS
D
L
D
L
Y
L
G
V
Q
AINWTEMFNPG
A
T
F
A
V
H
F
S
G
L
N
DTIRN
S
Q
Y
G
A
M
K
V
K
D
A
I
V
D
A
F
T
R
K
NLP
R
P
N
V
D
RDAPD
I
R
V
N
V
W
L
H
KE
T
A
S
I
A
L
D
LSGDGLHLRGYRDRAGIAPIK
E
T
L
A
A
A
I
V
M
R
SGWQPG
T
P
L
L
D
PMCGSG
T
L
L
I
E
A
A
M
L
A
T
D
R
A
P
G
L
H
R
G
R
W
G
F
S
G
W
A
Q
H
-----
D
-----------------
E
A
I
W
Q
E
V
K
A
E
A
Q
T
-
R
-
A
R
K
G
--
L
A
E
Y
S
S
H
F
Y
G
S
D
S
---------------------
D
A
R
V
I
Q
R
A
R
T
N
A
R
---
L
A
G
I
G
E
L
I
T
F
E
V
K
----
D
V
A
Q
L
T
N
P
L
P
K
GP
Y
G
T
V
L
S
N
P
P
Y
GESE
P
A
L
I
A
L
H
S
L
L
G
R
I
M
K
N
QFGG
W
N
L
S
L
F
S
AS
P
D
L
L
S
C
L
QLRAD
K
Q
Y
K
A
K
NGP
L
D
C
V
Q
K
N
Y
H
V
A
E
SMVA
E
D
Y
T
N
R
L
R
K
N
L
K
K
F
E
K
W
A
R
Q
E
GIECYRLYDADLPEYN
V
A
V
D
R
Y
AD
W
V
V
V
Q
E
Y
AH
K
A
R
Q
R
L
F
D
I
I
A
A
T
I
S
V
L
GIAPNK
L
V
L
K
T
REE
K
G
E
F
L
E
V
T
E
YN
A
H
L
W
V
N
LTDYLDTGLFLDH
R
I
A
R
R
M
L
G
Q
M
SKGKD
F
L
N
L
FSYTG
S
A
T
V
H
A
G
L
G
GAR
S
T
T
T
V
D
MS
R
T
Y
L
E
W
A
E
R
N
L
R
L
N
GLTGRA
H
R
L
I
Q
A
D
C
L
A
W
L
R
E
ANEQFD
L
I
F
I
D
P
P
TFSAFDVQRD
H
L
A
L
M
K
D
L
K
R
L
LRAG
G
T
I
M
F
S
N
NKRGFRMD
L
D
G
L
A
K
L
G
L
K
A
Q
E
ITQKTLSQDFARNRQIH
N
C
W
L
I
T
AA
90
HHSearch
60.87
22%
-20
- C2 -
-
1PDN
2
PRD_DROME
C:
[39-124]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
R
Q
L
R
V
S
H
G
C
V
S
K
I
L
N
R
Y
Q
-----
E
TGSIRPGVIGGSKPRIA
T
P
E
I
E
N
R
I
E
E
Y
K
R
-
S
--
S
P
G
--
M
F
--
S
W
E
I
R
E
K
L
I
R
E
-----
G
-----
V
CDRST
A
P
S
V
S
A
I
S
R
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
91
HHSearch
60.15
17%
35
- C2 -
-
6PAX
-
PAX6_HUMAN
A:
[39-130]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
R
I
L
Q
V
S
N
G
C
V
S
K
I
L
G
R
Y
Y
-----
A
TGSIRPRA
I
G
G
S
K
PRVA
T
P
E
V
V
S
K
I
A
Q
Y
K
Q
-
E
--
C
P
S
--
I
F
--
A
W
E
I
R
D
R
L
L
S
E
GVCTN
D
-----
N
-----
I
P
S
V
S
S
I
N
R
V
L
R
N
L
A
---
S
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
89
HHSearch
58.96
17%
-11
- C- -
-
1K78
-
PAX5_HUMAN
A:
[54-142]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
R
Q
L
R
V
S
H
G
C
V
S
K
I
L
G
R
Y
Y
-----
E
TGSIKPGV
I
G
G
S
K
P
KVA
T
P
K
V
V
E
K
I
A
E
Y
K
R
-
Q
--
N
P
T
--
M
F
--
A
W
E
I
R
D
R
L
L
A
E
RVCDN
D
-----
T
-----
V
P
S
V
S
S
I
N
R
I
I
R
T
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
87
Fugue
54.61
20%
-
- C- -
-
3C1D
-
RECX_ECO57
B:
[8-161]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------G
P
A
Y
A
R
L
L
D
R
A
V
R
I
L
A
V
R
D
H
S
E
Q
E
L
R
R
K
L
A
A
P
I
M
G
KN
G
P
E
E
I
DAT
A
E
D
Y
E
R
V
I
A
W
C
H
E
H
G
Y
L
D
--------------------------------
D
S
R
F
V
A
R
F
I
-
A
-
S
R
S
R
K
G
Y
G
--
P
A
R
I
R
Q
E
L
N
Q
K
-----
G
-----
I
-------
S
R
E
A
T
E
K
A
M
R
E
A
D
ID
W
A
A
L
A
R
D
Q
A
T
R
K
Y
G
E
P
L
P
T
V
F
S
E
K
V
K
I
Q
R
F
L
L
Y
R
GYLMEDIQDIW--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
96
HHSearch
54.51
18%
-169
- C2 -
-
5UNK
-
?
A:
[20-58]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
R
--
T
T
--
A
K
D
L
V
K
M
L
E
E
T
-----
G
-----
T
-----
K
V
S
I
S
T
V
K
R
V
L
Y
R
H
N
---
L
K
G
R
S
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
94
HHSearch
54.37
22%
86
- C3 -
-
5UI5
-
?
V:
[241-338]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
S
E
I
G
I
H
E
S
T
L
S
R
I
V
N
S
K
Y
VKTPV
G
TYSLRTFFVRESAEGLT
Q
G
E
L
M
K
L
I
K
E
I
V
E
N
E
D
K
R
K
P
--
Y
S
--
D
Q
E
I
A
N
I
L
K
E
K
-----
G
-----
F
-----
K
V
A
R
R
T
V
A
K
Y
R
E
M
L
G
---
I
P
S
S
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
Fugue
53.21
16%
-126
- C1 -
-
3RPF
1
?
C:
[3-74]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
V
R
F
F
G
P
I
K
E
E
N
F
F
I
K
A
N
-----
D
-----------------
L
K
E
L
R
A
I
L
Q
E
K
----------------
E
G
L
K
E
W
L
G
V
C
-----
A
-----
I
-----
A
L
N
D
H
L
I
D
N
L
--
N
T
P
---
L
K
D
G
D
V
I
S
L
L
------------
P
P
V
C
G
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
88
HHSearch
50.68
15%
38
* C3 *
-
2K27
-
PAX8_HUMAN
A:
[47-143]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
R
Q
L
R
V
S
H
G
C
V
S
K
I
L
G
R
Y
Y
-----
E
TGSIRP
G
V
I
G
G
S
K
P
KVA
T
P
K
V
V
E
K
I
G
D
Y
K
R
-
Q
--
N
P
T
--
M
F
--
A
W
E
I
R
D
R
L
L
A
E
-----
G
VCDND
T
-----
V
P
S
V
S
S
I
N
R
I
I
R
T
K
V
---
Q
Q
P
F
N
L
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
46.79
42%
116
- C2 -
-
4G1Q
1
?
A:
[509-534]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.51
42%
81
- C2 -
-
5C42
-
?
A:
[509-534]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
46.36
42%
116
- C2 -
-
4IG3
3
?
A:
[509-534]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
45.66
42%
109
- C2 -
-
5C24
-
POL_HV1B1
A:
[499-524]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
45.57
42%
83
- C2 -
-
4H4O
-
A:
[509-534]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
45.46
42%
106
- C2 -
-
4RW7
-
?
A:
[509-534]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
45.37
42%
105
- C2 -
-
4KFB
4
POL_HV1B1
A:
[509-534]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
45.15
42%
110
- C2 -
-
2ZD1
-
POL_HV1B1
A:
[509-534]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
44.97
42%
116
- C2 -
-
4KO0
1
A:
[509-534]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
44.96
42%
112
- C2 -
-
4RW9
-
POL_HV1B1
A:
[509-534]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
44.75
42%
116
- C2 -
-
4IDK
4
?
A:
[509-534]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
Q
P
D
K
-----
S
-----------------
E
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
-
K
E
K
V
--
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------