@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1924: (2016-03-30 )
MKGTIVIVGLGLIGGSIALAIKAKHPEAHIIGIDVSYHSLEVGKSLGVIDEIGESILIDGPKADLLIFCCPVKETEQLLMRLPGLRLKENVIVTDTGSTKGTIMEASTALRESGITFIGGHPMAGSHKSGVRAAKELLFENAYYLLTPTKDVTEDNVTDLKTWLSGTNAKFLVLSPNEHDEITGMLSHLPHIVAAALVNQTQSFTEEHPAAFRLAAGGFRDITRVASSDPRMWTDISISNKKTLTKQLTIWRDSMNQALEMLESEDATSIYAFFDGAKEFRDSLPVHQGGAIPSFYDLFVDVPDYPGVISEVTRYLGEEEISLTNIKILETREDIFGVLQITFQSDEDRDRAKRCIETRSNYTCHYE
Atome Classification :
(20 SA)
--------.........10........20........30........40........50.--.....-.-.60........70........80.....-...90-........100....-...-110-.......120-.......-130.......140.......150..-------......160.......170.......180-.......190.......200..-.....210.......220----.......230.......240.-......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------MK
G
T
I
V
I
V
G
L
GLIGG
S
I
A
L
A
I
K
AKHPE
A
H
I
I
G
I
D
V
S
Y
H
S
L
EVGKSLG
V
I
D
E
I--GE
S
I
L
-I-DGPKA
D
L
L
I
F
CCPV
K
E
T
E
Q
L
L
M
RLPGLR-LKE
N
V
-
I
V
TDTGSTK
G
T
I
M
E
A
-
S
T
A
-
L
R
E-S
G
I
T
F
IGGHP-MAGSH
K
S
-
G
V
R
A
A
K
E
L
L
F
EN
A
Y
Y
L
LTPTKD-VT-------E
D
N
V
T
D
L
K
T
W
LSGTN
A
K
F
L
V
LSPNE
H
D
E
I
-
T
G
M
L
S
H
L
P
H
I
V
A
A
A
L
V
N
Q
T
Q
S
F
-
T
E
EHP
A
A
F
R
LAAG
G
F
R
D
I
----
T
R
V
ASSDP
R
M
W
T
D
I
SISNK
K
T
-
L
T
K
Q
L
T
I
W
R
D
S
M
N
Q
A
L
E
M
L
ESEDA
T
S
I
Y
A
F
FD
G
A
K
E
F
R
D
SLPVHQGGAI
P
S
F
Y
D
L
FVDVPDYP
G
V
I
S
E
V
T
R
Y
LGEEEISL
T
N
I
K
I
L
E
T
R
E
D
I
F
G
V
L
Q
I
T
FQSDE
D
R
D
R
A
K
R
C
I
E
TRS
N
Y
T
C
HYE
2
PsiBlast_PDB
91.97
38%
-93
- C3 -
3B1F
1
?
A:
[8-286]
-----------
T
I
Y
I
A
G
L
G
L
I
G
A
S
L
A
L
G
I
K
R
D
H
P
H
Y
K
I
V
G
Y
N
R
S
D
R
S
R
D
I
A
L
E
R
G
I
V
D
E
A
--
T
A
D
F
K
-
V
-
F
A
A
L
A
D
V
I
I
L
A
V
P
I
K
K
T
I
D
F
I
K
I
L
A
D
L
D
-
L
K
E
D
V
-
I
I
T
D
A
G
S
T
K
Y
E
I
V
R
A
-
A
E
Y
Y
L
K
D
-
K
P
V
Q
F
V
G
S
H
P
-
M
A
----
S
-
G
A
V
A
A
N
V
N
L
F
E
N
A
Y
Y
I
F
S
P
S
C
L
-
T
K
-------
P
N
T
I
P
A
L
Q
D
L
L
S
G
L
H
A
R
Y
V
E
I
D
A
A
E
H
D
C
V
-
T
S
Q
I
S
H
F
P
H
I
I
A
S
S
L
M
K
Q
A
G
D
F
-
S
E
S
H
E
M
T
K
H
F
A
A
G
G
F
R
D
M
----
T
R
I
A
E
S
E
P
G
M
W
T
S
I
L
L
T
N
Q
E
A
-
V
L
D
R
I
E
N
F
K
Q
R
L
D
E
V
S
N
L
I
K
A
R
D
E
N
A
I
W
A
F
F
N
Q
S
R
Q
I
R
--------------------------------------------------------------------------------------
34
HHSearch
90.55
38%
-87
- C3 -
3B1F
1
?
A:
[6-289]
---------
E
K
T
I
Y
I
A
G
L
G
L
I
G
A
S
L
A
L
G
I
K
R
D
H
P
H
Y
K
I
V
G
Y
N
R
S
D
R
S
R
D
I
A
L
E
R
G
I
V
D
E
A
--
T
A
D
F
K
-
V
-
F
A
A
L
A
D
V
I
I
L
A
V
P
I
K
K
T
I
D
F
I
K
I
L
A
D
-
L
D
L
K
E
D
V
-
I
I
T
D
A
G
S
T
K
Y
E
I
V
R
A
-
A
E
Y
-
Y
L
K
D
K
P
V
Q
F
V
G
S
H
P
-
M
A
----
S
-
G
A
V
A
A
N
V
N
L
F
E
N
A
Y
Y
I
F
S
P
S
C
L
T
K
P
--------
N
T
I
P
A
L
Q
D
L
L
S
G
L
H
A
R
Y
V
E
I
D
A
A
E
H
D
C
V
-
T
S
Q
I
S
H
F
P
H
I
I
A
S
S
L
M
K
Q
A
G
D
F
-
S
E
S
H
E
M
T
K
H
F
A
A
G
G
F
R
D
M
----
T
R
I
A
E
S
E
P
G
M
W
T
S
I
L
L
T
N
Q
E
A
-
V
L
D
R
I
E
N
F
K
Q
R
L
D
E
V
S
N
L
I
K
A
R
D
E
N
A
I
W
A
F
F
N
Q
S
R
Q
I
R
K
N
M
-----------------------------------------------------------------------------------
3
PsiBlast_PDB
87.01
32%
-98
- C3 -
3GGG
2
?
D:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
29
PsiBlast_CBE
86.56
32%
-99
- C3 -
3GGG
2
?
A:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
25
PsiBlast_CBE
86.33
32%
-94
- C3 -
3GGO
2
?
C:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
4
PsiBlast_PDB
86.16
32%
-96
- C3 -
3GGO
2
?
A:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
22
PsiBlast_CBE
86.06
32%
-96
- C3 -
3GGP
3
?
C:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
5
PsiBlast_PDB
86.05
32%
-92
- C3 -
3GGP
3
?
A:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
27
PsiBlast_CBE
85.57
32%
-93
- C3 -
3GGG
2
?
C:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
33
HHSearch
85.43
33%
-90
- C3 -
2G5C
1
?
A:
[1-281]
---------
M
Q
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
-
K
V
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
-
I
-
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
T
D
K
--------
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
-------
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
I
K
R
M
E
I
-----------------------------------------------------------------------------------
24
PsiBlast_CBE
85.29
32%
-99
- C3 -
3GGO
2
?
D:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
23
PsiBlast_CBE
85.27
32%
-94
- C3 -
3GGP
3
?
B:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
21
PsiBlast_CBE
85.26
32%
-92
- C3 -
3GGP
3
?
D:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
28
PsiBlast_CBE
84.34
32%
-95
- C3 -
3GGG
2
?
B:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
6
PsiBlast_PDB
84.30
33%
-98
- C3 -
2G5C
1
?
A:
[3-262]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
-------
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
84.14
32%
-91
- C3 -
3GGO
2
?
B:
[35-307]
-----------
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
G
K
I
Y
G
Y
D
I
N
P
E
S
I
S
K
A
V
D
L
G
I
I
D
E
G
--
T
T
S
I
A
K
V
-
E
D
F
S
P
D
F
V
M
L
S
S
P
V
R
T
F
R
E
I
A
K
K
L
S
Y
I
--
L
S
E
D
A
-
T
V
T
D
Q
G
S
V
K
G
K
L
V
Y
D
-
L
E
N
-
I
L
---
G
K
R
F
V
G
G
H
P
-
I
A
G
T
E
K
S
-
G
V
E
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
T
K
K
-
T
D
-------
K
K
R
L
K
L
V
K
R
V
W
E
D
V
G
G
V
V
E
Y
M
S
P
E
L
H
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
A
L
V
D
T
L
I
H
M
-
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
K
S
D
P
I
M
W
R
D
I
F
L
E
N
K
E
N
-
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
-----------------------------------------------------------------------------------------
35
HHSearch
77.39
25%
-63
- C3 -
3KTD
2
?
A:
[8-339]
---------
S
R
P
V
C
I
L
G
L
G
L
I
G
G
S
L
L
R
D
L
H
A
A
--
N
H
S
V
F
G
Y
N
R
S
R
S
G
A
K
S
A
V
D
E
G
F
D
V
S
A
D
L
E
A
T
L
Q
-
R
-
A
A
A
E
D
A
L
I
V
L
A
V
P
M
T
A
I
D
S
L
L
D
A
V
H
T
-
H
-
A
-
P
N
N
-
G
F
T
D
V
V
S
V
K
T
A
V
Y
D
A
-
V
K
A
-
R
N
--
M
Q
H
R
Y
V
G
S
H
P
-
M
A
G
T
A
-
S
-
G
W
S
A
S
M
D
G
L
F
K
R
A
V
W
V
V
T
F
D
Q
L
F
D
G
TDIN
S
T
W
I
S
I
W
K
D
V
V
Q
M
A
L
A
V
G
A
E
V
V
P
S
R
V
G
P
H
D
A
A
-
A
A
R
V
S
H
L
T
H
I
L
A
E
T
L
A
I
V
G
D
N
----
G
G
A
L
S
L
S
L
A
A
G
S
Y
R
D
S
----
T
R
V
A
G
T
D
P
G
L
V
R
A
M
C
E
S
N
A
G
P
-
L
V
K
A
L
D
E
A
L
A
I
L
H
E
A
R
E
G
L
T
A
E
Q
-
P
N
I
E
Q
L
A
D
N
G
Y
R
S
R
I
R
Y
E
A
R
S
G
Q
--
S
S
R
P
V
L
R
L
-
H
P
G
T
P
N
W
E
K
Q
L
-
I
H
A
E
T
L
G
A
R
I
E
-------------------------------------------
1
PsiBlast_PDB
75.70
40%
-31
- C3 -
3DZB
-
?
A:
[4-298]
----------
K
T
I
Y
I
A
G
L
G
L
I
G
G
S
L
A
L
G
I
K
R
D
H
P
D
Y
E
I
L
G
Y
N
R
S
D
Y
S
R
N
I
A
L
E
R
G
I
V
D
R
A
--
T
G
D
F
K
-
E
-
F
A
P
L
A
D
V
I
I
L
A
V
P
I
K
Q
T
M
A
Y
L
K
E
L
A
D
L
D
-
L
K
D
N
V
-
I
I
T
D
A
G
S
T
K
R
E
I
V
E
A
-
A
E
R
Y
L
T
G
-
K
N
V
Q
F
V
G
S
H
P
-
M
A
G
S
-------
A
A
D
V
T
L
F
E
N
A
Y
Y
I
F
T
P
T
S
L
-
T
K
-------
E
T
T
I
P
E
L
K
D
I
L
S
G
L
K
S
R
Y
V
E
I
D
A
A
E
H
D
R
V
-
T
S
Q
I
S
H
F
P
H
L
L
A
S
G
L
M
E
Q
A
A
D
Y
-
A
Q
A
H
E
M
T
N
H
F
A
A
G
G
F
R
D
M
----
T
R
I
A
E
S
E
P
G
M
W
A
S
I
L
M
T
N
G
P
A
-
V
L
D
R
I
E
D
F
K
K
R
L
D
H
V
A
D
L
I
K
A
E
D
E
S
A
I
W
E
F
F
D
N
G
R
K
K
R
K
E
M
E
I
H
K
K
G
G
V
E
S
A
F
-----------------------------------------------------------------------
7
PsiBlast_PDB
72.23
29%
-53
- C3 -
4WJI
6
?
A:
[6-286]
-----------
T
I
A
L
I
G
I
G
L
I
G
S
S
I
A
R
D
I
R
E
K
Q
L
A
G
T
I
V
V
T
T
R
S
E
A
T
L
K
R
A
G
E
L
G
L
G
D
R
Y
--
T
L
S
A
A
-
E
-
A
V
E
G
A
D
L
V
V
V
S
V
P
V
G
A
S
G
A
V
A
A
E
I
A
A
-
H
-
L
K
P
G
A
-
I
V
T
D
V
G
S
T
K
G
S
V
I
A
Q
-
M
A
P
-
H
L
P
-
K
D
V
H
F
V
P
G
H
P
-
I
A
G
T
E
H
S
-
G
P
D
A
G
F
A
G
L
F
R
G
R
W
C
I
L
T
P
P
A
G
-
T
D
-------
E
E
A
V
A
R
L
R
L
F
W
E
T
L
G
S
M
V
D
E
M
D
P
K
H
H
D
K
V
-
L
A
I
V
S
H
L
P
H
I
I
A
Y
N
I
V
G
T
A
D
D
L
E
T
V
T
E
S
E
V
I
K
Y
S
A
S
G
F
R
D
F
----
T
R
L
A
A
S
D
P
T
M
W
R
D
V
C
L
H
N
K
D
A
-
I
L
E
M
L
A
R
F
S
E
D
L
A
S
L
Q
R
A
I
R
W
G
D
G
D
K
L
F
D
L
F
T
R
T
R
A
I
R
R
S
I
-----------------------------------------------------------------------------------
57
Fugue
63.32
17%
-71
- C3 -
2PV7
3
TYRA_HAEIN
A:
[13-292]
GFKTINSD
I
H
K
I
V
I
V
G
G
Y
G
K
L
G
G
L
F
A
R
Y
L
R
A
S
G
Y
P
--
I
S
I
L
D
R
E
D
W
A
V
A
E
S
I
L
-------------------
A
N
A
D
V
V
I
V
S
V
P
I
N
L
T
L
E
T
I
E
R
L
K
P
Y
---
L
T
E
N
M
L
L
A
D
L
T
S
V
K
R
E
P
L
A
K
M
L
E
V
-
H
T
----
G
A
V
L
G
L
H
P
M
F
G
A
D
I
A
S
M
A
K
Q
------------
V
V
V
R
C
D
G
-
R
F
-------
P
E
R
Y
E
W
L
L
E
Q
I
Q
I
W
G
A
K
I
Y
Q
T
N
A
T
E
H
D
H
N
M
T
Y
-
I
Q
A
L
R
H
F
S
T
F
A
N
G
L
H
L
S
K
Q
-
P
I
N
L
A
N
L
L
A
L
S
S
P
I
Y
R
L
E
L
A
M
I
G
R
L
F
A
Q
D
A
E
L
Y
A
D
I
------
I
M
N
L
A
V
I
E
T
L
K
Q
T
Y
D
E
A
L
T
F
F
E
N
N
D
R
Q
G
F
I
D
A
F
H
K
V
R
D
W
F
G
D
------------------------------------------------------------
Y
S
E
Q
F
L
K
E
S
R
Q
L
L
Q
Q
A
--------