@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2192: (2016-04-01 )
MTEQREKLLEIHNLKQYFNKGTASEVRAVDDISFDIYKGETLGLVGESGCGKSTTGRTIIRLYDATGGEVIYNGKDVHARKSRKEMLEFRRKMQMIFQDPYASLNPRMKVKDIIAEGIRIHGLAKTPEETNKQVYDLLETVGLSKEHAGRYPHEFSGGQRQRIGIARALAVQPEFIIADEPISALDVSIQAQVVNLLRQLQKEKNLTYLFIAHDLSMVKYISDRIGVMYFGKLVELAPANDLYHAPLHPYTESLLSAIPLPDPNYERTRVRKTYDPTSHNYKDGDEIKMREIAPGHFVYCSEEEEVMYKEKHAKLTAEAAAK
Atome Classification :
(37 SA)
.........10........20........30........40........50........60......----..70........80........90.-.......100---------........110........120.....-..130.......140......-.150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.....---..260-.......270--------------------.....----------...280..---------.....290.......300.......310.......320-------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
T
E
Q
R
E
K
L
L
E
I
H
N
L
K
Q
Y
F
NKG
T
A
S
E
V
R
A
VDD
I
S
F
D
I
YKG
E
T
L
G
LVGESGCGKSTTG
R
T
I
I
R
L
Y
DATG----
G
E
V
I
YNGKDV
H
A
R
K
S
R
K
E
M
L
E
F
R
R
K
-
M
Q
M
I
F
QDPY----------ASLNPRM
K
V
-
K
D
I
I
AE
G
I
R
I
HGLAKT
P
-
E
E
T
N
K
Q
V
Y
D
L
L
E
T
VGL
S
K
E
H
A-GRYPHEFSGGQ
R
Q
R
I
G
I
A
R
A
LAVQP
E
F
I
I
ADEPI
S
A
L
D
V
S
I
Q
A
Q
V
V
N
L
L
R
Q
L
Q
KEKN
L
T
Y
L
F
I
AH
D
L
S
M
V
K
Y
I
S
D
R
I
G
V
M
Y
F
G
K
L
VELAPANDLYHAPL
H
P
Y
T
E
S
L
L
S
A---IPLPD-PNY
E
R
T
R
V
R---------------------KTYDP----------TSHNYKDG---------D
E
I
K
M
R
EIAPG
H
F
V
Y
CS
E
E
E
E
V
M
Y
K
E
K
H
A
K
L
T
A
E
AAAK-------------------------------
130
Fugue
90.01
27%
-81
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
-
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
----
G
S
V
L
V
D
G
Q
E
L
-
T
T
L
S
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
H
F
------------
N
L
L
S
S
R
T
V
-
F
G
N
V
A
L
P
L
E
L
D
N
T
P
K
---
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
---
T
L
H
L
D
I
P
E
D
Y
Q
E
R
L
Q
---------------------
A
E
P
F
T
DCVPMLRLEF
T
G
Q
S
V
D
A
P
---------
L
L
S
E
T
A
R
R
F
N
V
N
N
N
I
I
S
A
Q
M
D
Y
A
G
G
V
K
F
G
I
M
L
T
E
M
H
G
T
QQDTQAAIAWLQEHHVKVEV-----------
5
PsiBlast_PDB
89.39
30%
-96
- C1 -
3TUI
1
METN_ECOLI
C:
[24-287]
-------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
-
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
----
G
S
V
L
V
D
G
Q
E
L
-
T
T
L
S
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
H
-
F
----------
N
L
L
S
S
R
T
V
F
-
G
N
V
A
L
P
----
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
TLH
L
D
I
P
E
-
D
Y
Q
E
R
L
Q
A
E
---------------------
P
F
T
D
-------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
88.91
30%
-98
- C1 -
3TUZ
1
METN_ECOLI
C:
[24-287]
-------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
-
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
----
G
S
V
L
V
D
G
Q
E
L
-
T
T
L
S
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
H
-
F
----------
N
L
L
S
S
R
T
V
F
-
G
N
V
A
L
P
----
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
TLH
L
D
I
P
E
-
D
Y
Q
E
R
L
Q
A
E
---------------------
P
F
T
D
-------------------------------------------------------------------------------------------------
114
HHSearch
87.59
30%
-104
- C1 -
3TUI
1
METN_ECOLI
C:
[23-266]
------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
-
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
----
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
-
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
H
F
N
------------
L
L
S
S
R
T
V
-
F
G
N
V
A
L
P
L
E
L
D
N
T
P
--
K
-
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
-
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
--------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
87.28
30%
-100
- C1 -
3DHW
-
METN_ECOLI
C:
[1-264]
-------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
-
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
----
G
S
V
L
V
D
G
Q
E
L
-
T
T
L
S
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
H
-
F
----------
N
L
L
S
S
R
T
V
F
-
G
N
V
A
L
P
----
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
TLH
L
D
I
P
E
-
D
Y
Q
E
R
L
Q
A
E
---------------------
P
F
T
D
-------------------------------------------------------------------------------------------------
132
Fugue
86.18
26%
-70
- C1 -
1OXS
23
?
C:
[1-352]
M
V
R
-----
I
I
V
K
N
V
S
K
V
F
K
K
G
---
K
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
----
G
E
L
Y
F
D
D
R
L
V
A
S
-
N
G
K
L
I
V
P
P
E
D
R
K
-
I
G
M
V
F
Q
T
W
------------
A
L
Y
P
N
L
T
A
-
F
E
N
I
A
F
P
L
T
N
M
K
--
M
S
K
-
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
I
-
H
H
V
L
-
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
I
G
E
---
I
N
E
L
E
-
G
K
V
T
N
E
G
V
V
IGSLRFPVSVSSDRAIIGIRP
E
D
V
K
L
----------
S
K
D
V
I
K
D
D
---------
S
W
I
L
V
G
K
G
K
V
K
V
I
G
Y
Q
G
G
L
F
R
I
T
I
T
P
L
D
S
E
E
E
I
F
T
Y
S
D
HPIHSGEEVLVYVRKDKIKVFEK--------
1
PsiBlast_PDB
85.89
35%
-92
- C1 -
4FWI
3
?
B:
[21-268]
-------------------------
I
K
A
A
D
G
I
S
L
D
I
L
E
N
S
V
T
A
I
V
G
E
S
A
S
G
K
S
T
I
I
E
A
M
T
K
T
L
P
P
N
G
RILS
G
R
V
L
Y
K
G
K
D
L
L
T
M
R
-
E
E
E
L
R
K
I
R
W
K
E
I
A
L
V
P
Q
A
A
Q
----------
Q
S
L
N
P
T
M
K
V
-
I
E
H
F
K
D
T
V
E
A
H
G
V
R
W
S
H
-
S
E
L
I
E
K
A
S
E
K
L
R
M
V
R
L
N
P
E
A
V
L
N
S
Y
P
L
Q
L
S
G
G
M
K
Q
R
V
L
I
A
L
A
L
L
L
D
P
V
V
L
I
L
D
E
P
T
S
A
L
D
V
L
T
Q
A
H
I
I
Q
L
L
K
E
L
K
K
M
L
K
I
T
L
I
F
V
T
H
D
I
A
V
A
A
E
L
A
D
K
V
A
V
I
Y
G
G
N
L
V
E
Y
N
S
T
F
Q
I
F
K
N
P
L
H
P
Y
T
R
G
L
I
N
S
---
I
----------------------------------------------------------------------------------------------------------------------------------------
135
Fugue
85.85
26%
-73
- C1 -
1Z47
1
?
A:
[11-355]
----
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
A
----
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
----
G
D
V
W
I
G
G
K
R
V
T
D
L
P
P
Q
K
------
R
N
-
V
G
L
V
F
Q
N
------------
Y
A
L
F
Q
H
M
T
V
-
Y
D
N
V
S
F
G
L
R
E
K
R
--
V
P
K
-
D
E
M
D
A
R
V
R
E
L
L
R
F
M
R
L
-
E
S
Y
A
-
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
G
T
L
F
V
A
S
F
I
G
E
---
S
N
V
W
T
-
R
A
V
Q
N
G
R
I
E
V
A-------------------
G
A
A
L
P
----------
V
D
P
A
V
S
E
G
S
E
V
A
V
V
V
R
P
K
D
V
E
L
Q
P
A
S
E
R
E
A
H
A
Q
V
V
R
S
A
F
K
G
S
Y
S
A
C
W
I
R
T
K
D
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
32
PsiBlast_CBE
84.13
32%
-98
- C1 -
2OLK
1
?
D:
[23-262]
------
Q
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
----
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
--
R
----------
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
-
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---
V
----------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
84.07
32%
-100
- C1 -
2OUK
1
?
A:
[23-262]
------
Q
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
----
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
--
R
----------
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
-
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---
V
----------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
83.76
32%
-97
- C1 -
2OLK
1
?
A:
[23-262]
------
Q
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
----
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
--
R
----------
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
-
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---
V
----------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
83.47
33%
-93
- C1 -
4U02
1
?
B:
[2-241]
-----
E
P
I
I
R
I
R
N
L
H
K
W
F
G
P
-----
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
----
G
E
V
V
V
D
G
L
S
V
---
K
D
D
R
A
L
R
E
I
R
R
E
-
V
G
M
V
F
Q
Q
------------
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
R
V
R
R
W
P
R
---
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
-
D
Q
A
-
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
---
V
----------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
83.47
32%
-98
- C1 -
2OLJ
4
?
A:
[23-262]
------
Q
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
----
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
--
R
----------
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
-
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---
V
----------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
83.38
33%
-91
- C1 -
4U02
1
?
A:
[2-241]
-----
E
P
I
I
R
I
R
N
L
H
K
W
F
G
P
-----
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
----
G
E
V
V
V
D
G
L
S
V
---
K
D
D
R
A
L
R
E
I
R
R
E
-
V
G
M
V
F
Q
Q
------------
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
R
V
R
R
W
P
R
---
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
-
D
Q
A
-
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
---
V
----------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
83.14
33%
-92
- C1 -
4U00
3
?
A:
[3-241]
------
P
I
I
R
I
R
N
L
H
K
W
F
G
P
-----
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
----
G
E
V
V
V
D
G
L
S
V
---
K
D
D
R
A
L
R
E
I
R
R
E
-
V
G
M
V
F
Q
Q
------------
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
R
V
R
R
W
P
R
---
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
-
D
Q
A
-
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
---
V
----------------------------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
82.85
34%
-84
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[5-235]
--------
L
H
I
G
H
L
S
K
S
F
Q
N
-----
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
----
G
E
I
S
L
S
G
K
T
I
F
S
K
N
T
N
L
P
V
R
E
--
R
R
-
L
G
Y
L
V
Q
E
------------
G
V
L
F
P
H
L
T
V
-
Y
R
N
I
A
Y
G
L
G
-
N
G
K
G
R
T
A
-
Q
E
-
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
-
E
L
A
-
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
-------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
82.73
32%
-96
- C1 -
2OUK
2
?
D:
[23-262]
------
Q
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
----
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
--
R
----------
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
-
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---
V
----------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
82.49
32%
-95
- C1 -
2OLK
1
?
C:
[23-262]
------
Q
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
----
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
--
R
----------
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
-
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---
V
----------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
82.36
32%
-96
- C1 -
2OLK
2
?
B:
[23-262]
------
Q
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
----
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
--
L
N
K
V
R
E
E
-
V
G
M
V
F
Q
--
R
----------
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
---
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
-
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---
V
----------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
82.34
33%
-90
- C1 -
2YYZ
3
?
A:
[4-238]
--------
I
R
V
V
N
L
K
K
Y
F
G
K
-----
V
K
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
----
G
E
I
Y
F
D
D
V
L
V
N
D
I
P
P
K
------
Y
R
E
-
V
G
M
V
F
Q
N
-
Y
----------
A
-
L
Y
P
H
M
T
V
-
F
E
N
I
A
F
P
L
R
A
R
R
I
S
K
---
D
E
V
E
K
R
V
V
E
I
A
R
K
L
-
L
I
D
N
L
L
-
D
R
K
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
S
P
K
N
M
F
V
A
S
F
I
G
N
---
P
P
---------------------------------------------------------------------------------------------------------------------------------------
86
PsiBlast_CBE
64.11
32%
-84
- C1 -
2FGJ
2
HLYBP_ECOLX
A:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
----
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
L
L
NRS
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
63.52
33%
-86
- C1 -
2PMK
1
A:
[21-235]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
----
A
L
A
D
P
N
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRS
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
83
PsiBlast_CBE
63.40
32%
-83
- C1 -
2FGJ
2
D:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
----
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRSIIDNI
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
85
PsiBlast_CBE
63.19
32%
-81
- C1 -
2FGJ
2
HLYBP_ECOLX
B:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
----
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRSIIDNI
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
89
PsiBlast_CBE
62.98
32%
-90
- C1 -
1XEF
3
HLYBP_ECOLX
C:
[19-233]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
----
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRSIIDNI
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
75
PsiBlast_CBE
62.84
33%
-83
- C1 -
2FF7
1
A:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
----
A
L
A
D
P
N
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRS
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
82
PsiBlast_CBE
62.72
32%
-78
- C1 -
2FFB
1
A:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
----
A
L
A
D
P
N
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRS
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
91
PsiBlast_CBE
62.63
32%
-81
- C1 -
1XEF
3
HLYBP_ECOLX
A:
[19-233]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
----
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
L
L
NRS
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
62.54
32%
-81
- C1 -
2FGK
2
HLYBP_ECOLX
A:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
----
A
L
A
D
P
N
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRS
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
87
PsiBlast_CBE
62.28
32%
-80
- C1 -
2FFA
2
A:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
----
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRS
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
80
PsiBlast_CBE
61.94
32%
-78
- C1 -
2FGK
2
HLYBP_ECOLX
B:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
----
A
L
A
D
P
N
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRSIIDNI
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
90
PsiBlast_CBE
61.69
32%
-84
- C1 -
1XEF
3
HLYBP_ECOLX
B:
[19-233]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
----
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRSIIDNI
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
84
PsiBlast_CBE
61.64
32%
-83
- C1 -
2FGJ
2
HLYBP_ECOLX
C:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
----
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRSIIDNI
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
61.26
32%
-77
- C1 -
2FGK
2
HLYBP_ECOLX
C:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
----
A
L
A
D
P
N
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRSIIDNI
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
88
PsiBlast_CBE
60.77
32%
-83
- C1 -
1XEF
3
D:
[19-233]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
----
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRSIIDNI
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
78
PsiBlast_CBE
60.14
32%
-80
- C1 -
2FGK
2
D:
[25-239]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
----
A
L
A
D
P
N
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRSIIDNI
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
59.84
32%
-85
- C1 -
3B5J
1
A:
[21-235]
----------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
A
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
----
G
Q
V
L
I
D
G
H
D
L
----
A
L
A
D
P
N
W
L
R
R
Q
-
V
G
V
V
L
Q
D
N
V
LLNRS
I
I
D
N
I
S
L
A
N
P
G
M
S
V
-
E
K
V
I
Y
A
A
-
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
E
G
Y
N
T
I
----
V
G
E
Q
G
A
-
G
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
S
L
Y
S
--------------------------------------------------------------------------------------------------------------------------------------------------