@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : bsu00260: (2016-06-01 )
MNRDQSDLHIDELLADPFGGNIEIPGSEAVKAEKEQVRLVDVLPEENKEKAIQLAGQIDHKNMQSIVLYGSQAQSKLLNFSHDMINHVQKKDVGEIGEILGELMKKLEQVNPDDLQSKKKGFLARMFGRVSSSLQEVLSKYQKTSVQIDRISLKLEHSKNALISDNKLLEQLYEKNKEYFAALNVYIAAGELKLEELKTKTIPELKQQAESSDHNQMAVQEVNDLIQFADRLDKRVHDLLLSRQITIQSAPQIRLIQNTNQALAEKIQSSIVTAIPLWKNQVAIALTLLRQRNAVDAQQKVSDTTNELLLKNAELLKTNTIETARANERGLVDIDTLKKVQESLISTLEETLTIQEEGRIKRRQAEEELMMMEGDLKQKLITIKER

Atome Classification :

(20 SA) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....-------.....10......-..20......---------..30----....----....-----40.....-...50....-.------...---------60-----......-------------.-------.70..---......80........--90------......--..-.100.....-.-.110---------------..-----....------.120-.......130.--------.--.-----------......140--------..----.....150.......160....-...----170....----..---------.180------------...---------------......-190.---...-..--------------.--------200.....---------..210....---.....220..-.------...---------.-------.230-.----------......240----------.--..---.....250----------.-....--------...260.-------------.-------...----------..------270...---...-.280.----.....-------.290.......300....------...310---.---------......320....----.--..330---------....----.....340-------------.---------------------..-------------------.....350.......--------360--........370.--......380....------------------------------------------------
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRD-------QSDLHIDELLADP-FGGNIEIPGS---------EAVK----AEKE----QVRL-----VDVLPEE-NKEKAIQLA-G------QID---------HK-----NMQSIV-------------L-------YGSQA---QSKLLNFSHDMINHVQ--K-------KDVGEI--GE-ILGELMKKL-E-QVNP---------------DD-----LQSK------KKGF-LARMFGRV--S--------S--S-----------LQEVLSKYQ--------KT----SVQIDRISLKLEHSKNALISDN-KLL----EQLYEKN----KE---------YF--------------AAL---------------NVYIAA-GELK---LEE-LK--------------T--------KTIPELKQ---------QAE--SSDH---NQMAVQ-EVN-D------LIQ---------F-------ADRL-D----------KRVHDLLL-----------S--RQ---ITIQSA-P----------Q-IRLI--------QNTNQAL-------------A-------EKI----------QS------SIVTAI---PLW-KNQVA----IALTL-------LRQRNAVDAQQKVSDTTN------ELLLKN---A---------ELLKTNTIETARA----N--ERG-----------LVDI----DTLKKVQ--------------E---------------------SL-------------------ISTLEETLTIQEEGR--------IK---RRQAEEELMMME--GDLKQKLITIKER------------------------------------------------
34 Fugue 77.0018% 7 - C3 -4TQT ? A:[14-490] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASKVIKGGTVITADRTF-------RADILIE--------DGKIAAIGD---------SLEG----DEVI----DASG-----CYVMP-------------G------GIDP--------HT-----HLQMPF-------------MGTYSSDDFDTGT---AAALAGGTTMVVDFVL--P-------DSEGNL--LD-ALQEWFQKA-G-KART---------------DYS----FHMA------ITGW-NERTFNEM--A--------E--V-----------VKRGIN------------------------TFHFMAYKGALMVND-DEM----FASFQRC----AE---------LG--------------AMP---------------LVHAEN-GDI----VAQ-LQ--------------A--------KLMAEGND---------GPE--AHAYSRPPEVEGE-ATN-R------AIM---------I-------ADQA-GVPLYVVHVSCEQSHEAIR-----------R--ARQKGMRVFGE-P----------L-IQHLTLDESEYHNRDWDYA-------------A-------RRVMSPPFRDKLNQD------SLWAGL---AAG-SLQCVATDHCAFTT-------EQKRYGIGNFTKIPNGTGGLEERMPVLWTR---GVRTGRLTPNEFVAVTSTNIAKILNIYP--QKGAVVPGADADLVIWDP----ETTKKIS--------------A---------------------KTQHSSIDYNVFEGFELKGLPIMTLSRGRIAFDKGQ--------VT---AKPGDGRFIEREPNGAVNRALSQWKEIVAPRKVERSA--------------------------------------
37 Fugue 75.6515% -32 * C6 *4D10 - CSN2_HUMAN B:[34-447] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDLENQYYNSKA-LKED----DP---------KAAL----SSFQ----KVLE-----LEGEKGE-WGFKALKQM-I------KINFKLTNFPEMMN-----RYKQLL-------------T-------YIRSAVT-RNYSEKSINSILDYIS--TS------KQMDLL--QE-FYETTLEAL-K-DAKN---------------DR-----LWFK------TNTK-LGKLYLEREEY--------G--K-----------LQKILRQLH--------QSCQTQLLEIYALEIQMYTAQK----NN-KKL----KALYEQS----LHIKSAIPHPLIM--------------GVI---------------RECGGK-MHLREGEFEK-AH--------------T--------DFFEAFKN---------YDE--SGSP------RRT-TCL-K------YLV---------L-------ANML-M----------KSGINPFD-----------S--QE---AKPYKNDP----------E-ILAM--------TNLVSAY-------------QNNDITEFEKI----------LK------TNHSNIMDDPFI-REHIE----ELLRN-------IRTQVLIKLIKPYTRIHI------PFISKE---------------LNIDVADVESL----L--VQC-----------ILD-----NTIH---------------------------------------GR-------------------IDQVNQLLELDHQKR--------GG---ARYTALDKWTNQ--LNSLNQAVVSKLA------------------------------------------------
35 Fugue 71.6517% -20 - C1 -4LLG - RPOD_ECOLI F:[6-612] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSQLKLLVTRGKE-QGYLTYAEVN---------DHLP----EDIV----DSDQ-----IEDIIQM-INDMGIQVM-GRTTDPVRMY---------MR-----EMGTVE-------------L-------LTREG---EIDIAKRIEDGINQVQ--C--------SVAEY--PE-AITYLLEQY-D-RVEAEEARLSDLITGFVDDPE-----LARE------KFAE-LRAQYVVT--R--------D--TIKATAQEEILKLSEVFKQFR--------LV----PKQFDYLVNSMRVMMDRVRTQE-RLI----MKLCVEQCKMPKK---------NF--------------ITLFTGNETSDTWF----NAAIAM-NKPW---SEK-LH--------------DVSEEVH--RALQKLQQ---------IEE--ETGL---TIEQVK-DIN-R------RMS---------I-------GEAK-A----------RRAKKEMV-----------E--AN---LRLVIS-IAKKYTNRGLQF-LDLI--------QEGNIGL-------------M-------KAV----------DKFEYRRGYKFSTY---ATW-WIRQA----ITRSI-------ADQARTIRIPVHMIETIN------KLNRIS---R---------QMLQEMGREPTPE----ELAERM-----------LMPE----DKIRKVL--------------KIAKEPISMETPIGDDEDSHLGDF-------------------IEDTTLELPLDSATT--------ES---LRAATHDVLAGL--TAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLD
30 Fugue 62.5619% -11 * C8 *1ZR6 ? A:[3-481] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-------AEFNSINACLAAA----DVEFHEE---------DSEG----WDMDGTAFNLRVDYDPAAIAIPRS-TEDIAAAVQ-C------GLD---------AG-----VQISAKGGGH---------S-------YGSYGFGGEDGHLMLELDRMYRVSVDD-------NNVATIQGGA-RLGYTALEL-L-D------------------------------------QGN-RALSHGTC--P--------AVGV-----------GGHVLGGGY--------GF----ATHTHGLTLDWLIGATVVLADA-SIV----HVSETEN----AD---------LF--------------WALRGGGGGFAIVSEFEFNTFEAP-EIIT---TYQ-VT--------------TTWNRKQHVAGLKALQD---------WAQ--NTMP---RELSMRLEINAN------ALN---------WEGNFFGNAKDL-K----------KILQPIMK-----------KAGGK---STISKL-V----------E-TDWY--------GQINTYLYGADLNITYNYDVH-------EYF----------YA------NSLTAP---RLS-DEAIQ----AFVDY-------KFDNSSVRPGRGWWIQWD------FHGGKN---S---------ALAAVSNDETAYA----H---RD-----------QLWLWQFYDSIYDYENNTSPYPESGFEFMQ---------------------GF-------------------VATIEDTLPEDRKGKYFNYADTTLT---KEEAQKLYWR-----GNLEKLQAIKAKYDPEDVFGNVVSVEPIAY------------------------------
36 Fugue 58.8921% 1 - C8 -4CIJ - ? A:[1-267] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGL-------KPCVDWLQVTFKT---------GQ---------DSVK----KCVE----KLEK-----VFEILGL-NEAEFLPLKNG------KYG---------YK-------QGVA-------------F-------QGNPV---LAVYYDGADDM------------------GIH--VE-MTGQGCRLF-E-LHTS---------------IN--------------------WYELFYRL--V--------Y--------------------EYE---------------VNITRLDVAVDDFKGYF------KI----NTLVKKL----KD--------------------------------------------------DEVT---SRF-KK--------------A--------RHIENIVI---------EGG----------------------------------------------------E----------TIGHTLYF-----------G--AP------SSD-I----------Q-VRFY--------EKNVQMG-------------M-------D-------------------------I---DVW--NRTE----IQLR----------DDRAHVVAQIIADDVL------PLGEIV---A---------GLLRNY-----------------------------IQF----RTRKATD--------------K---------------------N-------------------------------------------KK---RWPLARFWLNFL--GDVQPLRIAKQM-------------------------------------------------
38 Fugue 58.4112% 15 - C5 -4QIQ XYLE_ECOLI A:[7-470] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SYIFSITLVAT-LGGLLFGYDT---------AVIS----GTVE----SLNT-----VFVAPQNLSESAANSLL-G------FCV---------AS-----ALIGCI-------------I-------GGALG---GYCSNRFGRRDSLKIA--A-------VLFFIS--GV-GSAWPELGF-T-SINP---------------DNTVPVYLAGY------VPEFVIYRIIGGI--G--------V--G-----------LASMLSPMYIAELAPAHIR----GKLVSFNQFAIIFGQLLVYCVN-YFIARSGDASWLNT----DG---------WR--------------YMF---------------ASECIP-ALLF---LML-LY--------------T--------VPESPRWL---------MTL--ATQA---VQEIKH-SLD-R------LLM---------F-------GVGV-I----------VIGVMLSI-----------F--QQFVGINVVLY-Y----------A-PEVF--------KTLGAST-------------D-------IAL----------LQ------TIIVGV---INL-TFTVL----AIMTVDKFGRKPLQIIGALGMAIGMFSLGT------AFYTQAPGIV---------ALLSMLFYVAAFA----M--SWG-----------PVCW----VLLSEIF--------------P---------------------NA-------------------IRGKALAIAVAAQWL--------AN---YFVSWTFPMMDK--NSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETKGKTL---------------------
39 Fugue 54.3914% 18 - C6 -5A5T - ? A:[7-605] RPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKLAEEKTEAAKEESQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLS-------QIQRHHNQSTAI-----NLNNPES---------QSMH----LETR----LVQL-----DSAISME-LWQEAFKAV-E------DIH---------GL-----FSLS------------------------KKPP---KPQLMANYYNKVSTVF--W-------KSGN----AL-FHASTLHRL-Y-HLSR---------------EM-----RKNL------TQDE-MQRMSTRV--L--------L--A-----------TLSIPITPE--------RT----D-----IARLLDMDGIIVEKQR-RLA----TLLGLQA----PP---------TR--------------IGL---------------INDMVR---FN---VLQ-YV--------------V--------PEVKDLYN---------WLE--VEFN---PLKLCE-RVT-K------VLN---------W-------VREQ-P----------EK-EPELQ-----------Q--YV---PQLQSN-T----------I-LRLL--------QQVAQIY-------------Q-------SIE----------FS------RLTSLV---P-F-VDAFQ----LERAI-------VDAARHCDLQVRIDHTSR------TLSFGS---D---------LNYATREDAPIGP----H--LQS-----------MPS-----EQIRNQL--------------T---------------------AM-------------------SSVLAKALEVIKPAH--------IL---QEKEEQHQLAVT--AYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVR-----------
33 Fugue 49.8117% 34 - C6 -3VWA - CEX1_YEAST A:[5-544] --------------------------------------------------------------------------------------------------------------------------------------------------------PLHMSISNFQFPYTIEETAITETALWQCFDGTRKADSLPVTVFKAKRSPENESLILNAVHKSKILKIPGLCTVLETFDSDPQSTFIVTERVVPFPWDNLG----SLSQ-----NKFGVEL-GISQLLATL-G------FLK---------NFVLGTLSKDSVFINIKGEWVLFGLEL-------CSSKE---GLSAFEFASRARSYYN--IIGSQLPCEDPNTI--DSMGLGLLIKSLMAPSCLP---------------KD-----WIVNVNMISDGKIT-IENFRKRL--E--------N--T-----------ETWRSNPLI--------NF----YQELRELHIKDPQGKLVV----MSNL----ENLYLES----RE---------IFRNLTPGMIENFIIPELC---------------EIIKLLMTQSI---SSN-AS--------------H--------KLVPFLAI---------VLD--LTSE---TNTFPV-GFN-D------LIT---------Q-------SFKLPD----------RQVRFLLLIYLPKLIGPLSK--SE---ISSRIY-P----------HFIQGL--------TDSDATL-------------R-------LQT----------LK------TIPCIV---SCLTERQLN----NELLR-------FLAKTQVDSDVEIRTWTV------IIISKI---S---------TILSTSVGNRSNI----L--ATA-----------FTKSLK--DPQVKPR--------------L---------------------AA-------------------LYGLEKSIELFDVNT--------IANKILTVIAPGLLDKS--PIVRGRAKILFEEYLEKLEKEAQLIQTN---------------------------------
32 Fugue 48.058% 11 * C5 *2XUB - RPC3_HUMAN A:[1-532] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQA-------EIKL-CSLLLQEH-FGEIVEKIGV---------HLIR----TGSQ----PLRV-----IAHDTGT-SLDQVKKAL-C------VLV---------QH-----NLVSYQ-------------V-------HKRGV---VEYEAQCSRVLRMLRY--P-------RYIYTT--KT-LYSDTGELI-V-EELL---------------LN-----GKLT------MSAV-VKKVADRL--TETMEDGKTM--D-----------YAEVSNTFV--------RL----ADTHFVQRCPSVDGIYWQANLD-RFH----QHFRDQA----IV---------SA--------------VAN---------------RMDQTS-SEIV---RTM-LRMSEITTSSSAPFTQP--------LSSNEIFRSLPVGYNISKQV--LDQY---LTLLAD-DPL-E------FVGKSGDSGGGMY-------VINL-H----------KALASLAT-----------A--TL---ESVVQE-R----------F-GSRC--------ARIFRLV-------------L-------QKE----------QK------QVEDFA---MIP-AKEAK----DMLYK-------MLSENFMVNILSAARMLL------HRCYKS---I---------ANLIERRQFETKE----N--KRL-----------LEKS----QRVEAII--------------A---------------------SM-------------------QLQEIEEMITAPERQ--------QL---ETLKRNVNKLDA--SEIQVDETIFLLESYIECTMK----------------------------------------
19 PsiBlast_PDB 45.2122% -11 - C4 -2FRH SARA_STAAW A:[2-117] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHMAIT-KIN-DCFELLSMVT---------Y-------ADKL-K----------S-----LI-----------K--KE---FSISFE-E----------F-AVLT--------YISENKE-------------K-------EYY----------LK------DIINHL---NYK-QPQVV----KAVKI-------LSQEDYFDKKRNEHDERT------VLILVN---A---------QQRKKIESLLSRV----N--KR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 41.5032% 45 - C7 -2KC3 - APOE_HUMAN A:[1-57] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K---VEQAVE--------------T--------EPEPELRQ---------QTEWQSGQR---WELALG-RFW-D------YLR---------W-------VQTL-S----------EQVQEELL-----------S--SQ---VT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 HHSearch 39.418% 14 - C7 -4UY3 - EZRA_STAA1 A:[78-181] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------KYLAPV--EE-KIHNAEALL-D-KFSF---------------NA-----S---------------QSEIDDA--N--------E--L-----------MDSYEQSYQ--------QQ----LEDVNEIIALYKDNDELYDKCK-VDY----REMKRDV----LA---------NR--------------HQF---------------GEAASL-LETE---IEK-FE--------------P--------RL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 38.4732% 82 - C7 -1NFN - APOE_HUMAN A:[23-67] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQR---WELALG-RFW-D------YLR---------W-------VQTL-S----------EQVQEELL-----------S--SQ---VT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 38.2432% 71 - C7 -1EA8 - APOE_HUMAN A:[23-57] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQR---WELALG-RFW-D------YLR---------W-------VQTL-S----------EQVQEELL-----------S--SQ---VT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 37.9132% 74 - C7 -1H7I - APOE_HUMAN A:[23-57] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQR---WELALG-RFW-D------YLR---------W-------VQTL-S----------EQVQEELL-----------S--SQ---VT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 36.9732% 73 - C7 -1OR3 - APOE_HUMAN A:[22-64] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGQR---WELALG-RFW-D------YLR---------W-------VQTL-S----------EQVQEELL-----------S--SQ---VT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11 PsiBlast_PDB 36.8232% 76 - C7 -1GS9 - APOE_HUMAN A:[22-57] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGQR---WELALG-RFW-D------YLR---------W-------VQTL-S----------EQVQEELL-----------S--SQ---VT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 36.8132% 70 - C7 -1NFO - APOE_HUMAN A:[23-67] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQR---WELALG-RFW-D------YLR---------W-------VQTL-S----------EQVQEELL-----------S--SQ---VT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10 PsiBlast_PDB 35.9632% 79 - C7 -1OR2 - APOE_HUMAN A:[23-68] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQR---WELALG-RFW-D------YLR---------W-------VQTL-S----------EQVQEELL-----------S--SQ---VT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7 PsiBlast_PDB 35.5832% 69 - C7 -1B68 - APOE_HUMAN A:[23-59] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQR---WELALG-RFW-D------YLR---------W-------VQTL-S----------EQVQEELL-----------S--SQ---VT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------