@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu03060: (2016-06-05 )
MWEQLYDPFGNEYVSALVALTPILFFLLALTVLKMKGILAAFLTLAVSFFVSVWAFHMPVEKAISSVLLGIGSGLWPIGYIVLMAVWLYKIAVKTGKFTIIRSSIAGISPDQRLQLLLIGFCFNAFLEGAAGFGVPIAISAALLVELGFKPLKAAALCLIANAASGAFGAIGIPVITGAQIGDLSALELSRTLMWTLPMISFLIPFLLVFLLDRMKGIKQTWPALLVVSGGYTAVQTLTMAVLGPELANILAALFSMGGLALFLRKWQPKEIYREEGAGDAGEKKAYRAADIAKAWSPFYILTAAITIWSLPAFKALFQEGGLLYQSTLLFKMPFLHQQIMKMPPIAPSAMPLDAVFKVDLLSATGTAILAAVIVTGLFSKKFSSRDAFASLKETGKELWVPIMTICFVMGFANLANFAGLSSSIGLALAKTGDLFPFVSPVLGWIGVFITGSVVSNNALFGHLQVVTGAQIGAGSDLLLAANTAGGVMAKLVSPQSIAIAAAAVGQTGKESKLFKRTVAYSLILLLIICIWTFILARLGV
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.--........10.--.......20-..-----.....--.-.30........40.-----.......50-----------------------........60..---.---------.---....70......-..80...----.....90.........100.......110---------------------........-120---------....--..-...130.......140-----------.......---..-------------150.....--.-------------------.160.......170..---.....-------------180-...---..-----...190-----------.....--------------------...200-----.......---210.......-----220-...----------------------------....----.230.....-..240-.--------......-----.--.250...--.---------------...260....-...---270...--....280...-------....290...---....300---.........-310--....-----....---320-----....--...330.---.--.....340.-......350...-------.-..--.360.......370-----....----.------..---380--------.--.--.-.----.....390.......-400.----------------------......410.......-420...-.....430.--..----.----.--.----.-.440.-.-----..------------...450.......460-------------.------------..--.....470..-.....480-..---......-.490--...-.-.------..-..500.-.......-----.510-.---........520..---------.....530.....--..540--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
--
W
E
Q
L
Y
D
PF
G
N
E
--
Y
V
S
A
L
V
A
L
--
T
P
-----
I
L
F
F
L
--
L
-
A
L
T
V
L
K
M
K
G
I
L
A
A
F
-----
L
T
L
A
V
S
F
F
V
-----------------------
S
V
W
A
F
HM
P
V
E
K
A
---
I
---------
S
---
S
V
L
L
G
IGSG
L
W
P
-
I
G
Y
I
V
L
M
----
A
V
W
L
Y
K
-
I
AVKTG
K
F
T
I
I
R
S
S
IAGI
S
P
D
----------------------
Q
R
L
Q
L
L
L
I
-
G
-----------
F
C
F
N
--
A
F
-LEGAAGFG
V
P
I
A
I
S
-------------
A
A
L
L
V
E
L---GF-------------
K
P
L
K
A
A
A
L
--
C
-------------------
L
I
ANAASGAFGAIG
I
P
---
V
ITGA-------------QI--GD
L
---
S
A
-----
L
E
L
S
R
------------
T
L
M
W
T
--------------------
L
P
M
I
S
F
-----
L
I
P
F
L
L
V
---
F
L
L
D
R
M
K
G
I
K
-----QT--W
P
A
----------------------------
L
L
V
V----SG
G
Y
T
A
V
Q
T
-
L
T
M
---
A
--------VL
G
P
E
L
-----
A
--
N
I
L
A
A
L
F
--S---------------MG
G
L
A
L
F
L
RK-W
Q
P
---
K
E
I
Y
R
E--EGAGDAGEK
K
-------
A
Y
R
A
A
D
I
A
K
A---WS
P
F
Y
-----
I
L
T
A
A
I
T
I
W-S
L
---
P
A
F
K
-----
A
L
F
Q
---EG
G
-----
L
L
Y
Q
--
S
T
L
L
FKM---
P
--
F
L
H
Q
Q
I
MKM-PPIAPSAMPL
D
A
-------
V
-
F
K
--
V
D
L
LSAT
G
T
A
I
L
A
A
-----
V
I
V
T
----
G
------
L
F
---
S
----------K--K--F-S----S
R
D
A
F
A
S
L
K
E
T
G
K
E
L
-
W
V
P
I
----------------------
M
T
I
C
F
V
M
G
F
A
N
L
A
N
F
A-GL-SSS-I
G
L
A
L
AK-T--GD----L----
F
--
P
----
F
-
V
S
P
V
L
-
G
-----
W
I
------------
G
V
F
I
T
G
S
VVSNN
A
L
F
--------------
G
------------
H
L
--
Q
V
V
T
GAQIGA-GS
D
L
L
L
---
A
A---NTAG
G
V
-
M
A
----
K
LV-S-P------Q
S
-
I
A
I
--
A
-
A
AAVGQT-----G
K
---
E
---
S
K
L
F
K
R
T
V
A
Y
S
L
I
---------
L
L
L
I
I
C
I
W
T
F
I
L
A
--RLGV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
86.10
16%
-157
- C4 -
4UZY
2
?
A:
[9-650]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQPA
R
P
I
A
EGQ
Y
T
Q
T
I
Y
T
L
I
K
E
QK
F
A
E
A
I
Q
H
L
Q
Y
Q
L
Q
N
V
P
ES
R
A
A
L
S
L
L
G
Y
C
Y
--
Y
Y
T
G
Q
Y
D
M
A
S
Q
--
M
Y
E
Q
L
V
T
L
--
Y
P
SN
E
D
Y
K
L
Y
Y
A
--
Q
-
S
L
Y
K
G
G
M
Y
P
E
A
S
K
A
-----
V
V
K
V
E
G
H
Q
K
-----------------------
A
V
T
T
L
L
V
A
C
S
Y
E
Q
DD
L
---------
T
---
G
C
R
R
Q
L
D
K
C
A
P
E
D
P
D
T
M
V
N
T
----
G
C
I
M
F
K
-----
E
G
K
F
E
A
A
R
Q
K
F
N
D
Y
Q
P
E
----------------------
L
L
Y
N
I
A
L
C
-
Y
-----------
Y
K
T
K
--
Q
F
-
G
P
A
L
K
H
L
A
E
I
I
E
K
A
-------------
V
R
E
H
P
E
L
---
S
V
GSDGMEVRSVGNS
Q
T
L
K
E
T
A
L
--
I
-------------------
E
A
F
N
L
K
A
A
I
E
Y
T
M
K
N
V
---
E
A
A
K
E
-------------
A
L
--
T
D
M
PPR
A
E
-----
E
E
L
D
P
------------
V
T
L
H
N
--------------------
S
A
L
I
N
M
DSD
P
T
G
G
F
K
K
L
N
---
F
L
L
Q
S
P
P
F
P
P
-----
E
T
--
F
A
N
----------------------------
L
L
L
L
Y
C
KP
S
H
G
F
Y
D
L
A
A
-
D
V
L
---
A
E
N
P
Q
Y
A
G
K
L
L
S
P
D
L
-----
Y
--
D
Y
L
Q
A
A
I
--
G
R
YKS
P
E
E
A
F
R
R
F
D
E
L
A
T
R
H
V
E
Q
L
R
R
-
L
T
K
---
Q
I
Q
D
A
R
--
I
A
R
D
N
D
A
I
K
R
-------
A
I
N
E
Y
D
E
A
L
E
---
A
Y
I
P
G
-----
L
M
A
M
A
S
I
Y
W
-
D
M
EL
Y
S
N
V
E
-----
K
I
F
R
---
Q
S
A
-----
E
F
C
S
--
E
H
E
V
W
K
L
---
N
--
V
A
H
T
F
F
M
Q
D
-
N
H
Y
K
E
A
I
R
Y
Y
E
P
-------
V
-
V
K
K
N
A
D
N
L
L
G
V
T
A
I
V
L
A
N
-----
L
C
V
S
----
Y
------
I
M
---
T
SQ
N
E
E
A
E
E
L
M
R
--
K
--
V
-
E
----
K
E
E
E
R
S
S
M
Q
D
P
D
K
P
C
F
H
L
C
I
----------------------
I
N
L
V
I
G
T
L
Y
C
A
K
G
N
Y
E
-
F
G
-
V
S
R
-
I
I
K
S
L
E
E
-
T
--
D
T
----
W
----
Y
--
Y
----
A
-
K
R
C
F
L
-
A
-----
L
I
------------
E
N
L
A
K
H
M
I
V
L
K
D
S
S
F
--------------
T
------------
E
I
--
M
A
F
L
N
E
A
E
K
H
-
G
K
D
I
R
V
---
V
F
---
N
Q
-----------------
S
------
R
T
-
I
A
S
--
E
-
A
R
M
L
K
K
M
-----
F
L
---
K
---
L
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
69.04
13%
-149
- C6 -
4R0C
6
?
A:
[66-486]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
Y
L
---
F
---------
T
---
T
L
V
G
N
F
T
G
-
F
A
P
-
L
G
-
V
V
L
V
----
A
M
L
G
L
G
-
V
A
E
Q
S
G
L
L
S
V
S
L
A
S
L
V
R
R
S
S
G
----------------------
G
A
L
V
F
T
V
A
F
A
-----------
G
V
L
S
--
S
L
-
T
-
V
D
A
G
Y
V
V
L
I
P
L
A
-------------
G
L
V
F
Q
L
A
---
G
R
-------------
P
P
I
A
G
I
A
T
--
A
-------------------
F
A
A
V
S
G
G
F
S
A
N
L
L
V
G
P
V
D
A
T
L
A
G
L
-------------
S
T
E
A
A
H
I
I--
D
P
-----
D
-
R
--------------------------------------------------
T
V
A
A
T
--------
G
------------------------------------------------------
N
Y
W
F
I
I
A
S
T
-
F
L
V
------------------------------
T
-
G
--
L
------------------
V
T
L
I
T
R
T
L
T
E
P
---
R
L
A
H
A
N
--
T
V
A
D
A
S
V
D
A
P
-------
Q
I
H
S
R
A
M
K
W
T
G
L
T
L
A
I
L
L
-----
A
G
L
A
L
L
V
L
--------
P
N
D
-----
A
P
L
R
---
H
P
---------------------------------------
D
----
T
G
S
-------
V
-
L
G
--
S
P
---
F
I
H
G
L
V
V
I
V
-----
A
L
I
A
----
G
------
I
C
G
A
V
Y
----------
G
--
R
--
V
S
G
QFRN
S
G
A
V
I
T
A
M
E
V
T
M
A
S
M
-
A
G
Y
L
----------------------
V
L
M
F
F
A
A
Q
F
V
A
W
F
N
Y
S
-
Q
L
-
G
L
L
L
A
V
K
G
A
A
W
-
L
G
A
L
T
----
V
P
K
V
V
L
--
L
----
L
-
L
F
V
V
L
-
T
-----
A
L
------------
I
N
L
M
I
G
S
A
S
A
K
W
S
I
L
--------------
A
------------
P
V
--
F
I
P
M
L
M
L
L
G
I
-
S
P
E
A
S
Q
---
A
A
---
Y
R
V
G
D
S
-
S
T
----
N
I
I
-
T
-
P
------
L
M
-
P
Y
F
V
L
V
-
L
G
F
A
R
R
Y
-----
Q
P
ETG
I
---
G
T
L
I
A
L
M
L
P
Y
S
L
T
---------
L
L
L
G
W
S
V
L
L
G
V
W
I
--
G
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
69.01
19%
-124
- C3 -
4YB8
5
?
A:
[1-464]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
ND
L
E
R
L
F
N
P
S
A
I
A
--
V
V
G
A
S
K
D
P
--
S
K
-----
I
G
S
Q
I
--
L
R
N
L
L
S
Y
G
F
K
G
K
V
Y
P
I
-----
N
P
T
A
D
E
L
M
-----------------------------
G
L
K
C
Y
P
K
---
V
---------
S
---
D
V
P
D
K
V
D
V
A
V
I
S
-
V
P
S
D
K
V
L
----
G
V
-
I
D
D
-
C
G
K
A
G
V
K
F
A
V
V
I
T
S
G
F
K
E
V
G
N
----------------------
E
E
L
E
E
E
L
V
-
R
-----------
R
A
H
S
Y
G
M
R
-
V
L
G
P
N
I
F
G
Y
L
Y
A
P
A
-------------
R
-
L
N
A
T
F
---
G
P
-------------
K
D
V
L
S
G
N
V
--
A
-------------------
F
I
S
Q
S
G
A
L
G
I
A
L
M
G
Y
T
---
V
V
E
N
I
-------------
G
I
--
S
S
I
---
V
S
-----
V
G
N
K
A
------------
D
L
D
---------------------------------
D
V
D
L
L
D
F
---
F
D
K
D
P
N
T
G
V
I
-----
M
I
--
Y
L
E
----------------------------
G
I
A
P
----
G
R
G
R
M
F
I
D
V
-
A
S
R
---
V
--------
S
L
R
K
P
I
-----
I
--
V
I
K
A
G
R
T
--
E
---------------
V
G
A
R
A
A
A
S
H
T
-
G
S
I
AGS
V
A
I
Y
E
S
A
F
K
Q
S
G
I
L
M
A
K
S
-------
V
E
D
A
F
D
W
T
K
A
---
L
S
W
N
P
-----
I
P
E
G
E
R
L
I
V
-
L
T
---
N
G
G
G
-----
A
G
V
Q
---
S
T
D
-----
T
F
A
D
--
N
G
I
Y
L
S
K
---
P
P
E
S
L
I
Q
E
I
K
K
F
V
P
P
F
A
S
F
A
N
P
I
D
-----------------------------------
I
T
----
G
------
M
A
---
P
----------
D
--
D
--
W
-
Y
----
Y
M
G
T
L
A
A
L
K
N
P
D
-----
V
D
A
----------------------
L
T
V
L
Y
C
Q
T
--
A
V
T
T
P
I
-
G
V
-
A
K
G
-
I
V
D
A
I
K
E
-
A
--
G
N
----
S
----
K
--
P
----
V
-
T
V
G
M
V
-
G
---------------------------------------------------------------------
G
P
E
V
A
E
-
A
V
S
F
L
N
---
K
Q
---
R
I
------
A
----
A
Y
P
-
T
-
P
------
E
R
-
A
S
S
--
A
-
M
S
A
L
Y
A
Y
-----
A
R
---
A
---
R
S
Y
V
M
K
S
L
A
V
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
60.70
17%
-149
- C2 -
4O2X
-
MALE_ECOLI
A:
[5-483]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
--
G
K
L
V
I
W
I
N
G
D
K
--
G
Y
N
G
L
A
E
V
--
G
K
-----
K
F
E
K
D
TG
I
-
K
V
T
V
E
H
P
D
K
L
E
E
K
F
-----
P
Q
V
A
A
T
-------------------------------------------------------------
G
D
G
P
-----
D
I
I
F
W
----
A
H
D
R
F
G
-
G
Y
A
Q
S
G
L
L
-------
A
E
I
T
P
D
----------------------
K
A
F
Q
D
K
L
Y
-
P
-----------
F
T
W
D
--
A
V
-
R
Y
N
G
K
L
I
A
Y
P
I
A
V
E
-------------
A
-------------------------------
L
--
S
-------------------
L
I
Y
N
K
-----
D
L
L
P
N
P
---
P
K
T
W
E
-------------
E
I
--
P
A
L
---
D
K
-----
E
L
K
A
K
G
K
S
---------
A
L
M
F
N
--------------------
L
Q
E
P
Y
F
-----
T
W
P
L
I
A
A
DGG
Y
A
F
K
Y
E
N
G
K
Y
-----
D
I
--
K
D
V
----------------------------
G
V
D
N
----
A
G
A
K
A
G
L
T
F
-
L
V
D
---
L
--------
I
K
N
K
H
M
NADTD
Y
--
S
I
A
E
A
A
F
--
N
---------------
K
G
E
T
A
M
T
I
N
G
---------------------------------------
P
W
A
---
W
S
N
I
D
-----
T
S
K
V
N
Y
G
V
T
-
V
L
---
P
T
F
K
-----
G
Q
P
-----------------------
S
K
---
P
--
F
V
G
V
L
S
A
G
I
-
N
A
A
S
P
N
K
E
L
A
K
E
-------
F
-
L
E
--
N
Y
L
L
T
D
E
G
L
E
A
V
N
K
D
KPLG
A
V
A
L
----
K
------
S
Y
---
E
----------
E
--
E
--
L
-
A
----
K
D
P
R
I
A
A
T
M
E
N
A
Q
K
G
-
E
I
--------------------------------
M
P
N
I
P
Q
M
S
-
A
F
-
W
Y
A
-
V
R
T
A
V
I
N
-
A
--
A
S
----
G
----
R
--
Q
----
T
-
V
D
E
A
L
-
A
-----
A
A
------------
Q
T
N
A
A
A
N
L
E
K
I
K
K
L
R
--------------
N
------------
V
I
--
T
--
S
A
W
K
V
I
L
-
Y
N
D
D
I
H
---
N
F
---
T
Y
V
T
D
V
-
I
V
----
K
V
V
-
G
-
Q
IS
K
A
K
A
H
T
-
I
T
V
--
E
-
A
H
S
T
G
Q
A
-----
L
I
---
L
---
S
T
W
K
S
K
A
E
K
Y
C
Q
E
---------
L
Q
Q
N
G
L
T
V
S
I
I
H
E
--
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
58.38
20%
-117
- C3 -
4C3X
9
?
A:
[23-530]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
--
W
T
--------
S
--
E
C
D
V
L
V
V
G
--
S
G
---------------------
G
G
A
L
T
G
A
-----
Y
T
A
A
A
-------------------------------------
Q
G
---
L
---------
T
---
T
I
V
L
E
K
T
D
R
F
G
G
-
T
S
A
Y
S
G
A
----
S
I
W
L
P
G
-
T
Q
V
Q
E
------
R
A
G
L
P
D
--
S
T
----------------------
E
N
A
R
T
Y
L
R
-
A
-----------
L
L
G
D
--
A
E
-
S
E
R
Q
D
A
Y
V
E
T
A
P
A
V
-------------
V
A
L
L
E
Q
N
---
P
N
-------------
I
E
F
E
F
R
A
F
P
D
Y
-------------------
Y
K
A
E
G
R
M
D
T
G
R
S
I
N
P
L
---
D
L
D
P
A
-------------
D
I
--
G
D
L
---
A
G
KVRPE
L
D
Q
D
R
------------
T
G
Q
D
H
--------------------
A
P
G
P
M
I
-----
G
G
R
A
L
I
G
---
R
L
L
A
A
V
Q
S
--------
T
--
G
K
A
----------------------------
E
L
R
T
----
E
S
V
L
T
S
L
I
V
-
E
D
G
---
R
--------
V
V
G
A
E
V
-----
E
S
G
G
E
T
Q
R
I
K
--
A
---------------
N
R
G
V
L
M
A
A
G
G
-
I
E
G
---
N
A
E
M
R
E
--
Q
A
-
G
T
P
G
K
A
I
WSMGPFG
A
N
T
G
D
A
I
S
A
G
---
I
A
V
G
G
-----
A
T
A
L
L
D
Q
A
W
-
F
C
---
P
G
V
E
QPDGS
A
A
F
M
VGV
R
G
G
-----
L
V
V
D
--
S
A
---
G
E
---
R
--
Y
L
N
E
------------
S
L
P
Y
D
Q
-------
F
G
R
A
--
M
D
A
H
D
D
N
G
S
A
V
P
S
F
-----
M
I
F
D
SREG
G
------
G
L
---
P
----------
A
--
I
--
C
-
I
----
P
N
T
A
P
A
K
H
L
E
A
G
--
T
-
W
V
G
A
----------------------
D
T
------
L
E
E
L
A
A
K
T
-
G
L
P
A
D
A
-
L
R
S
T
V
E
K
-
F
--
N
D
----
A
----
A
--
K
----
L
G
V
D
E
E
F
-
H
RGEDP
Y
D
------------
A
F
F
C
P
P
N
G
G
A
N
A
A
L
--------------------------------
T
A
I
E
N
G
P
F
Y
A
-
A
R
I
V
L
S
---
D
L
---
G
T
K
G
G
L
-
V
T
D
VNG
R
V
L
-
R
-
A
------
D
G
-
S
A
I
--
D
G
L
Y
A
A
G
N
T
----------
S
---
A
S
L
S
G
R
F
Y
P
G
P
G
V
---------
P
L
G
T
A
M
V
F
S
Y
R
A
A
--
Q
D
M
A
K--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
58.01
15%
-133
- C4 -
4J5T
4
CWH41_YEAST
A:
[1-811]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A
E
F
M
E
E
Y
Q
K
F
T
N
E
S
L
LWAPYRSNCY
F
G
M
R
P
R
YVHESPL
I
M
G
I
M
W
F
N
SLSQDGLHSLRHFATPQDKLQ
K
Y
G
W
EVYDPR
I
G
G
K
E
V
F
I
D
EKNNLN
L
T
V
Y
F
V
K
S
KNGE
N
W
S
V
R
V
--
Q
G
E
P
L
D
P
K
R
P
S
--
T
A
S
V
V
L
Y
F
--
S
Q
-----
N
G
G
E
I
--
D
-
G
K
S
S
L
A
M
I
G
H
D
G
P
N
-----
D
M
K
F
F
G
Y
S
K
-----------------------
E
L
G
E
Y
H
L
T
V
K
D
N
---
F
G
H
Y
F
KNPEY
E
---
T
M
E
V
A
P
G
S
D
C
S
K
-
T
S
H
L
S
L
Q
I
P
DK
E
V
W
K
A
R
-
D
V
F
Q
S
L
V
S
D
S
I
R
D
I
L
E
R
-
P
A
D
----------------------
L
I
P
S
V
L
T
I
-
R
NLYNFNPGN
F
H
Y
I
Q
K
--
T
F
D
L
T
K
K
D
G
F
Q
F
D
I
T
Y
N
K
LGTTQSIST
R
E
Q
V
T
E
L
I
T
W
---
S
L
-------------
N
E
I
N
A
R
F
D
--
K
Q
F
S
F
G
EGPDSIES
V
E
V
K
R
R
F
A
L
E
T
L
S
N
L
L
G
G
I
G
Y
F
---
Y
G
N
Q
L
I
D
RETEFDESQFT
E
I
--
K
L
L
---
N
A
-----
K
E
E
G
P
------------
F
E
L
F
T
S
V
PSRGFFPRGF
Y
W
D
E
G
F
H
L
L
Q
I
M
E
Y
-----
D
F
D
L
A
F
E
---
I
L
A
S
W
F
E
M
I
E
-----
D
D
SG
W
I
A
----------------------------
R
E
I
I
----
L
G
N
E
A
R
S
K
V
P
Q
E
F
---
Q
--------
V
Q
N
P
N
I
-----
A
--
N
P
P
T
L
L
L
--
A
---------------
F
S
--
E
M
L
S
R
A
-
I
E
N
---
I
G
D
F
M
T
--
N
N
L
E
A
N
P
G
L
L
-------
T
E
Y
A
K
K
I
Y
P
K
---
L
L
K
H
Y
-----
N
W
F
R
K
S
Q
T
G
-
L
I
---
D
E
Y
E
-----
E
I
L
E
---
D
E
G
-----
I
W
D
K
IH
K
N
E
V
Y
R
W
VGR
T
--
F
T
H
C
L
P
S
G
M
-
D
D
Y
P
R
A
Q
P
P
D
V
A
-------
E
-
L
N
--
V
D
A
L
A
W
V
G
V
M
T
R
S
M
-----
K
Q
I
A
----
H
------
V
L
--------------
K
--
L
--
T
-
Q
----
D
E
Q
R
Y
A
Q
I
E
Q
E
V
V
E
N
-
L
D
L
L
HWSENDN
C
Y
C
D
I
S
I
DPEDDE
I
R
E
F
V
C
H
-
E
G
Y
V
S
V
L
P
F
A
L
K
L
-
I
P
K
-
N
S
P
K
L
E
K
-
V
--
V
A
----
L
----
M
--
S
----
D
-
P
E
K
I
F
-
S
-----
D
Y
------------
G
L
L
---
S
L
S
R
Q
D
D
Y
F
--------------
G
KDENYWR
G
P
I
W
M
N
I
--
N
Y
L
C
L
D
A
M
R
Y
Y
Y
P
E
V
I
L
---
D
V
---
A
G
E
A
S
N
-
A
K
----
K
L
Y
-
Q
-
S
------
L
K
-
I
N
L
--
S
-
N
N
I
Y
K
V
W
-----
E
E
---
Q
---
G
Y
C
Y
E
---
N
Y
S
P
I
DGHGTGAEH
F
T
G
W
T
A
L
V
V
N
I
L
G
--
R
F
R
S
H
H
H
H
HH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
52.85
15%
-183
- C6 -
4R1I
-
?
A:
[338-503]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-
G
----
E
R
E
V
V
N
A
M
A
E
S
M
S
T
L
-
G
L
Y
L
----------------------
V
I
I
F
F
A
A
Q
F
V
A
F
F
N
W
T
-
N
I
-
G
Q
Y
-
I
A
V
K
G
A
V
F
L
--
K
E
VGLA
G
----
S
V
L
F
----
I
-
G
F
I
L
I
-
C
-----
A
F
------------
I
N
L
M
I
G
S
A
S
A
Q
W
A
V
T
--------------
A
------------
P
I
--
F
V
P
M
L
M
L
A
G
Y
-
A
P
E
V
I
Q
---
A
A
---
Y
R
I
G
D
S
-
V
T
----
N
I
I
-
T
-
P
------
M
M
-
S
Y
F
--
G
-
L
I
M
A
T
V
M
K
Y
KKD
A
G
---
V
---
G
T
L
I
S
M
M
L
P
Y
S
A
F
---------
F
L
I
A
W
I
A
L
F
C
I
W
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
52.78
17%
-138
* C4 *
2B39
1
CO3_BOVIN
A:
[30-1661]
TPN
I
L
R
L
E
S
E
E
T
V
V
L
E
A
H
GGQG
T
I
Q
V
S
V
T
V
H
D
FPAKKQVLSN
E
N
T
Q
L
N
S
NNGY
L
S
T
V
T
I
K
I
P
ASKELKSDK
G
H
K
F
V
T
V
VATFGN
V
Q
V
E
K
VVLISLQS
G
Y
L
F
I
Q
T
DKTIYTPG
S
T
V
L
Y
R
V
F
T
V
D
HKLLPVG
Q
T
V
F
I
T
I
E
T
PD
G
I
P
V
K
R
D
S
K
S
SQNQF
G
I
L
T
L
S
W
NIPE
L
V
N
M
G
V
W
K
I
K
A
Y
Y
EDSPQ
Q
V
F
S
A
E
F
E
V
K
E
Y
VLPS
F
E
V
Q
L
E
P
EEKFYYIDDPDGLKV
N
I
I
A
R
F
LYGE
Q
V
D
G
T
A
F
V
I
F
G
V
Q
D
GDRRISLTHSLTRVPINDG
N
G
E
A
I
L
K
RQVLLNGVQPSRADALVG
K
S
I
Y
V
S
A
T
V
I
L
QSG
S
D
M
V
E
A
E
R
T
GIPIVTSP
Y
Q
I
H
F
T
KTP
K
F
F
K
P
A
M
P
F
D
L
M
V
Y
V
T
N
PDGSPARHIPVVTQGS
N
V
Q
S
L
T
QDDGVAK
L
S
I
N
T
Q
NKRDPL
T
I
T
V
R
T
KKDNIPEG
R
Q
A
T
R
T
M
Q
A
L
P
Y
N
T
QGNSNN
Y
L
H
L
S
V
PRVELKPG
E
T
L
N
V
N
F
H
L
R
T
D
P
GEQAKIR
Y
Y
T
Y
M
I
M
N
KGKLL
K
V
G
R
Q
Y
R
E
P
GQD
L
V
V
L
P
L
T
ITSDFIP
S
F
R
L
V
A
Y
Y
TLINAKGQREVV
A
D
S
V
W
V
D
V
KDSCMG
T
L
V
V
K
N
GGKEEKHHRPG
Q
Q
I
T
L
K
I
E
A
D
Q
G
A
R
V
G
L
V
A
V
D
K
G
V
F
V
LNKKNKLT
Q
R
K
I
W
D
V
V
EKADIGCTPGSGRN
Y
A
G
V
F
T
D
A
G
L
T
L
K
T
SQGLETQQRADPQCPQSV
Q
L
M
E
K
R
M
D
K
A
G
Q
Y
SS
D
L
R
K
C
C
E
D
G
M
RDNPMKFP
C
Q
R
R
A
Q
F
ILQG
D
A
C
V
K
A
F
L
D
C
C
E
Y
I
T
Q
L
R
--
Q
Q
H
S
R
D
G
A
L
D
D
--
D
I
I
P
E
E
D
I
--
I
S
-----
R
S
Q
F
P
--
E
-
S
W
L
W
T
V
I
E
D
L
K
Q
A
D
-----
K
N
G
I
S
T
K
L
M
-----------------------
N
V
F
L
K
D
S
I
T
T
W
E
---
I
---------
L
---
A
V
S
L
S
D
K
K
G
I
C
V
-
A
D
P
Y
E
V
T
----
V
M
Q
D
F
F
-
I
D
L
R
L
-
P
Y
S
V
V
R
N
E
--------------------------------
Q
V
E
I
R
-
A
-----------
I
L
Y
N
--
Y
-----------
R
E
A
E
N
-------------
L
K
V
R
V
E
L
---
L
Y
-------------
N
P
----
A
F
--
C
-------------------
S
L
A
T
A
K
K
R
H
Q
Q
T
I
T
I
P
--------------------------------
A
-----
R
S
S
V
A
------------
V
P
Y
V
I
--------------------
V
P
L
K
I
G
-----
L
H
E
V
E
V
K
---
A
A
V
Y
N
H
F
I
S
D
-----
G
V
--
K
K
T
----------------------------
L
K
V
V
----
P
E
G
V
R
V
N
K
T
-
V
A
V
---
R
--------
T
L
N
P
E
H
-----
L
-----------
G
---------------
Q
G
G
V
--------
Q
R
---
E
E
V
-------------
P
A
-------
A
D
L
S
D
Q
V
P
D
T
---
E
S
E
T
K
-----
I
L
L
Q
G
T
P
V
---
A
---
Q
M
T
E
-----
D
A
I
D
---
G
E
R
-----
L
K
H
------
L
I
Q
T
---
P
SG
C
G
E
Q
N
M
I
G
M
-
T
P
T
V
I
A
V
H
Y
L
D
S
-------
T
-
D
Q
--
W
E
K
F
G
L
E
K
R
Q
E
S
L
E
-----
L
I
R
K
----
G
------
Y
T
---
Q
----------
Q
L
A
F
--
R
-
Q
----
K
S
S
A
Y
A
A
F
Q
Y
R
P
P
S
T
-
W
-------------------------
L
T
A
Y
V
V
K
V
F
A
L
A
A
N
L
I
-
A
I
-
D
S
K
-
D
L
C
E
T
V
K
-
W
--
L
I
----
L
----
E
--
K
----
Q
-
K
P
D
-----------------------
G
I
F
Q
E
D
G
P
V
I
H
Q
E
M
I
--------------
G
------------
G
F
--
R
D
T
R
E
K
D
V
S
L
-
T
A
F
V
L
I
---
A
L
---
H
E
A
K
D
I
-
C
E
----
A
Q
V
-
N
-
S
------
L
G
-
R
S
I
--
A
-
K
A
G
D
F
L
E
-----
N
H
---
Y
---
R
E
L
R
R
------------------
P
Y
T
V
A
I
A
A
Y
A
L
A
--
L
L
G
K
LEG
D
R
L
T
K
F
L
N
T
AKEKN
R
W
E
E
P
NQ
K
L
Y
N
V
E
A
T
S
Y
A
L
L
A
L
L
A
R
KDYDTT
P
P
V
V
R
W
L
N
E
QRYYGGGYGST
Q
A
T
F
M
V
F
Q
A
L
A
Q
Y
Q
K
D
VPDHKE
L
N
L
D
V
S
I
Q
L
PSRNS
A
V
R
H
R
I
L
WESASL
L
R
S
E
E
T
KEN
E
R
F
T
V
K
A
E
G
K
G
Q
G
T
L
S
V
V
T
V
Y
H
A
K
L
KGKVSCKK
F
D
L
R
V
S
I
R
P
A
P
ETVKKPQDAK
G
S
M
I
L
D
I
C
T
K
Y
LGDQDA
T
M
S
I
L
D
I
S
M
M
TGFSPD
V
E
D
L
K
T
L
S
TGVDRYIS
K
Y
E
M
N
R
DSNKN
T
L
I
I
Y
L
DKVSHT
V
E
D
C
L
S
F
K
V
H
Q
YFNVGL
I
Q
P
G
A
V
K
V
Y
S
YYNLDE
T
C
I
R
F
Y
H
P
D
KEDGMLSKLCHK
D
T
C
R
C
A
EENCFT
L
E
D
R
L
D
K
A
C
EPGVDYVYKTRLI
Q
K
K
L
E
DDFDEY
I
M
V
IENIIKSGSD
E
V
Q
V
K
Q
E
R
K
F
I
S
H
IKCREALKLKEG
A
H
Y
L
V
W
G
V
SSDLWGEKP
K
I
S
Y
I
IGKD
T
W
V
E
LWPEAEECQD
E
E
N
Q
K
Q
C
E
D
L
A
N
F
T
E
N
M
V
V
FGCPN
17
Fugue
44.03
14%
0
- C- -
1ITK
19
KATG2_HALMA
A:
[18-731]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K
R
P
K
S
N
Q
D
W
W
PSKLNL
E
I
L
D
Q
--
N
A
R
D
V
G
P
V
E
D
D
FD
Y
A
E
E
F
Q
K
L
D
L
E
A
-----
V
K
S
D
L
--
E
-
E
L
M
T
S
S
Q
D
W
W
P
A
D
Y
GHY
G
P
L
F
I
R
M
A
W
H
S
A
GTYRTADGRGGAAGGRQRFAPI
N
S
W
P
D
N
A
N
L
D
K
A
---
R
---------
R
L
L
L
P
I
K
Q
K
Y
G
Q
K
I
S
W
-
A
D
L
M
I
L
A
----
G
N
V
A
I
E
S
M
G
F
K
T
F
G
Y
A
G
G
R
E
D
A
F
E
E
D
K
A
VNWGPEDEFETQERFDEPGEIQ
E
G
L
G
A
S
V
M
-
G
-----------
L
I
Y
---
V
N
-
P
E
G
P
D
G
N
P
D
P
E
A
S
A
-------------
K
N
I
R
Q
T
F
D
R
M
A
M
-------------
N
D
K
E
T
A
A
L
--
I
-------------------
A
G
G
H
T
F
G
K
V
H
G
A
D
D
P
E
---
E
N
L
G
P
-------------
E
P
--
E
A
A
---
P
I
-----
E
Q
Q
G
L
GWQNKNMITSG
I
E
G
P
W
T
--------------------
Q
S
P
T
E
W
-----
D
M
G
Y
I
N
N
---
L
L
D
Y
E
W
E
P
E
K
G
PGG
A
W
Q
--
W
A
P
KSEELKNSVPDAHDPD
E
K
Q
T
P
M
M
L
T
T
D
I
A
L
K
R
----
D
P
D
Y
R
E
V
M
E
-
T
F
Q
E
N
P
M
--------
E
F
G
M
N
F
-----
A
--
K
A
W
Y
K
L
T
H
R
D
---------------
M
G
P
P
E
R
F
L
G
P
-
E
V
P
---
D
E
E
M
I
W
--
Q
D
P
L
P
D
A
D
Y
D
-------
L
I
G
D
E
E
I
A
E
L
---
K
E
E
I
L
D
SDLS
V
S
Q
L
V
K
T
A
W
A
S
A
---
S
T
Y
R
-----
D
S
D
K
---
R
G
G
ANGAR
L
R
L
E
--
P
Q
K
N
W
E
V
---
N
--
E
P
E
Q
L
E
T
V
L
-
G
T
L
E
N
I
Q
T
E
F
N
D
S
RSDG
T
Q
V
-
S
L
--
A
D
L
I
V
L
G
G
N
A
A
V
E
Q
-----
A
A
A
N
----
A
------
G
Y
---
D
----------
V
--
E
I
P
F
-
E
----
P
G
R
V
D
A
G
P
E
H
T
D
A
P
S
-
F
D
A
L
----------------------
K
P
K
--
V
D
G
V
R
N
Y
I
Q
D
D
-
I
T
-
R
P
A
-
E
E
V
L
V
D
N
-
A
--
D
L
----
L
NLT-
A
--
S
----
E
-
L
T
A
L
I
-
G
-----
G
M
R
S
I
GANYQDTDL
G
V
F
T
D
E
P
E
T
L
T
N
D
F
F
--------------
V
------------
N
L
L
D
M
G
T
E
W
E
P
A
A
D
-
S
E
H
R
Y
K
---
G
L
---
D
R
D
T
G
E
-
V
K
----
W
E
A
-
T
---------
R
-
I
D
L
--
I
-
F
G
S
N
D
R
L
-----
R
A
---
I
---
S
E
V
Y
G
S
A
D
A
E
K
K
L
---------
V
H
D
F
V
D
T
W
S
K
V
M
K
L
D
R
F
D
L
E--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
40.11
42%
-161
- C7 -
4H7O
-
?
A:
[208-249]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
--------------
G
------------
N
I
--
E
V
G
E
G
A
K
I
G
S
-
G
S
V
V
L
Q
---
A
V
P
P
H
T
T
V
A
G
V
-
P
A
----
R
I
V
-
G
R
P
------
Q
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
38.64
13%
-147
- C6 -
4F35
-
?
D:
[306-445]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
W
G
V
L
----------------------
L
L
F
G
G
G
L
C
L
S
N
V
L
K
Q
T
-
G
T
-
S
V
F
-
L
A
N
A
L
S
D
M
V
--
S
H
----
M
----
G
--
I
F
V
V
I
L
-
V
V
A
T
F
-
V
-----
V
F
------------
L
T
E
F
A
-
S
N
T
A
S
A
A
L
L
--------------
I
------------
P
V
--
F
A
T
V
A
E
A
F
G
M
-
S
P
V
L
L
S
---
V
L
---
I
A
V
A
A
--
S
C
----
A
F
M
-
L
-
P
------
V
A
T
P
P
N
--
A
-
I
V
F
A
S
G
H
-----
I
K
---
Q
---
S
E
M
M
R
V
G
L
Y
L
N
I
A
---------
C
I
G
L
L
T
A
I
A
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
37.78
10%
-141
* C3 *
1IEZ
-
RIBB_ECOLI
A:
[1-217]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
Q
-
T
L
L
S
S
F
G
T
P
F
E
R
-------
V
-
E
N
--
A
L
A
A
L
R
E
G
R
G
V
M
V
L
-----
D
D
E
D
----
R
ENEGDM
I
F
---
P
----------
A
--
E
--
T
-
M
----
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
-----------------------------
V
C
L
C
I
T
-
E
D
R
R
K
Q
L
-
D
L
-
P
M
M
-
V
E
N
N
T
S
A
-
Y
--
G
T
----
G
----
F
--
T
----
V
-
T
I
E
A
A
-
E
-----
G
V
------------
T
T
G
V
S
A
A
D
R
I
T
T
V
R
A
A
I
A
DGAKPSD
L
N
R
P
G
------------
H
V
--
F
P
L
R
A
Q
A
----
G
G
V
L
T
R
---
G
G
---
H
T
E
A
T
I
D
L
M
----
T
L
A
-
G
-
F
------
K
P
-
A
G
V
--
L
-
C
E
L
T
N
D
D
-----
G
T
---
M
ARA
P
E
C
I
E
F
A
N
K
H
N
M
A
---------
L
V
T
I
E
D
L
V
A
Y
R
Q
A
--
H
E
R
K
AS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
37.71
35%
-118
- C7 -
3GVD
2
?
A:
[192-252]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
G
D
----
R
----
H
--
P
----
K
-
I
R
E
-----------------------
G
V
M
I
G
A
G
A
----
K
I
L
--------------
G
------------
N
I
--
E
V
G
R
G
A
K
I
G
A
-
G
S
V
V
L
Q
S
V
P
A
H
---
T
T
A
A
G
V
-
P
A
----
R
I
V
G
K
-
P
------
E
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
36.06
36%
-137
- C7 -
3V4E
3
ATRF2_STAAC
A:
[138-178]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
T
W
F
G
--------------
G
------------
H
V
--
A
V
L
P
G
V
T
I
G
E
-
G
S
V
I
-----------
G
A
G
S
V
-
V
T
----
K
D
I
-
P
-
P
------
H
S
-
L
A
V
--
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
36.02
36%
-138
* C7 *
4EGG
1
ATRF2_STAAC
A:
[135-175]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
T
W
F
G
--------------
G
------------
H
V
--
A
V
L
P
G
V
T
I
G
E
-
G
S
V
I
-----------
G
A
G
S
V
-
V
T
----
K
D
I
-
P
-
P
------
H
S
-
L
A
V
--
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
35.08
36%
-136
- C7 -
4DCL
-
ATRF2_STAAC
A:
[135-175]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
T
W
F
G
--------------
G
------------
H
V
--
A
V
L
P
G
V
T
I
G
E
-
G
S
V
I
-----------
G
A
G
S
V
-
V
T
----
K
D
I
-
P
-
P
------
H
S
-
L
A
V
--
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
34.71
36%
-137
- C7 -
3FTT
-
ATRF2_STAAC
A:
[135-175]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
T
W
F
G
--------------
G
------------
H
V
--
A
V
L
P
G
V
T
I
G
E
-
G
S
V
I
-----------
G
A
G
S
V
-
V
T
----
K
D
I
-
P
-
P
------
H
S
-
L
A
V
--
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
32.30
33%
-180
- C5 -
1DGJ
2
?
A:
[398-448]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
--
M
I
A
P
G
L
G
L
E
F
-
P
K
D
L
V
L
---
V
Q
---
N
T
T
G
G
T
-
F
G
----
Y
K
F
-
S
-
P
------
T
M
-
E
A
L
--
V
-
G
V
A
V
M
A
T
-----
G
R
---
P
---
C
H
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
30.07
16%
-96
- C6 -
4R1I
-
?
A:
[82-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
T
H
T
V
K
N
F
T
G
F
-
A
P
L
G
----------------------
T
V
-
L
V
S
L
L
G
V
G
I
A
E
K
S
-
G
L
-
I
S
A
-
L
M
R
L
L
L
T
K
S
--
P
R
----
K
----
L
--
T
----
T
-
F
M
V
V
F
-
T
-----
G
I
------------
L
S
N
T
A
-
S
E
-
L
G
Y
V
V
L
--------------
I
------------
P
L
--
S
A
V
I
F
H
S
L
G
R
-
H
P
L
A
G
L
---
A
A
---
A
F
A
G
V
S
-
G
G
----
Y
S
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
29.59
13%
-114
* C6 *
4R0C
3
?
A:
[70-175]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
T
L
V
G
N
F
T
G
F
-
A
P
L
G
-----------------------
V
V
L
V
A
M
L
G
L
G
V
A
E
Q
S
-
G
L
-
L
S
V
-
S
L
A
S
L
V
R
R
S
--
S
G
----
G
----
A
--
L
----
V
-
F
T
V
A
F
A
G
-----
V
L
------------
S
S
L
T
---
V
D
A
G
Y
V
V
L
--------------
I
------------
P
L
--
A
G
L
V
F
Q
L
A
G
R
-
P
P
I
A
G
I
---
A
T
---
A
F
A
A
V
S
-
G
G
----
F
S
A
-
N
-
L
------
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------