@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu15530: (2016-06-24 )
MKKAYLTVCSNQQIADRVFQMVLKGELVQGFTTPGQFLHLKVSEAVTPLLRRPISIADVNFEKNEVTIIYRVDGEGTRLLSLKQQGELVDVLGPLGNGFPVNEVQPGKTALLVGGGVGVPPLQELSKRLIEKGVNVIHVLGFQSAKDVFYEEECRQYGDTYVATADGSYGETGFVTDVIKRKKLEFDILLSCGPTPMLKALKQEYAHKEVYLSMEERMGCGIGACFACVCHTNESETSYVKVCLDGPVFKAQEVAL
Atome Classification :
(20 SA)
-.........10........20......--..30........40.....----------------------------...50........60........70.-----------.-----------------.--.--....80-....-..-.-.90......-------.-------.100..-.....110........120.......130--..----.--..--....140.......150......--.--------160.---.-------------...----.-----...170......-.-180-.-----..----.....190.......--200.-...---...-210........220.......230.......240.......250....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
K
K
A
Y
L
T
VCSN
Q
Q
I
A
D
R
V
F
Q
M
V
L
K
G
E
L
--
V
QGFTTPG
Q
F
L
H
L
K
V
S
E
A
V
----------------------------
T
P
L
L
RRPI
S
I
A
D
V
NFEKN
E
V
T
I
I
Y
R
V-----------D-----------------G--E--G
T
R
L
L
S
-LKQQ-G
E
-
L
-
V
D
V
LGPLGN-------G-------FPVNEV-QPG
K
T
A
L
-
L
VGGGVGVP
P
L
Q
E
L
S
K
R
L
I
----
E
K----G--V
N
--
V
I
H
V
LGFQ
S
A
K
D
V
F
Y
E
E
E
C
R
QYG--D--------
T
--
Y
---
V
-------------
A
TA----D-----GSYGET
G
F
V
T
D
V
-
I
-
K
R--K-----KL----
E
F
D
I
L
L
SCG
P
T
P
M
L
K
--
A
L
K
Q
-
E
YA---
H
K
E
-
V
-
Y
L
S
M
E
E
RMG
C
G
I
G
A
C
F
A
C
VCHTNESET
S
Y
V
K
V
C
LDGPVFKAQEVAL
48
Fugue
78.66
46%
-110
- C2 -
1EP3
2
PYRK_LACLM
B:
[2-262]
S
Q
L
Q
E
M
M
T
V
V
S
Q
R
E
V
A
Y
N
I
F
E
M
V
L
K
G
T
L
--
V
D
E
M
D
L
P
G
Q
F
L
H
L
A
V
P
N
G
-----------------------------
A
M
L
L
R
R
P
I
S
I
S
S
W
D
K
R
A
K
T
C
T
I
L
Y
R
I
-----------
G
-----------------
D
--
E
TT
G
T
Y
K
L
S
-
K
L
E
S
-
G
A
-
K
-
V
D
V
M
G
P
L
G
N
-------
G
-------
F
P
V
A
E
V
-
T
S
T
D
K
I
L
-
I
I
G
G
G
I
G
V
P
P
L
Y
E
L
A
K
Q
L
E
----
K
T
----
G
--
C
Q
--
M
T
I
L
L
G
F
A
S
E
N
V
K
I
L
E
N
E
F
S
N
L
K
N
V
T
--------
L
--
K
---
I
-------------
A
T
D
----
D
-----
G
S
Y
G
T
K
G
H
V
G
M
L
-
M
-
N
E
--
I
-----
D
F
----
E
V
D
A
L
Y
T
C
G
A
P
A
M
L
K
--
A
V
A
K
-
K
Y
D
---
Q
L
E
R
L
-
Y
I
S
M
E
S
R
M
A
C
G
I
G
A
C
Y
A
C
V
E
H
D
K
E
D
E
S
H
A
L
K
V
C
E
D
G
P
V
F
L
G
K
Q
L
S
L
2
PsiBlast_PDB
77.84
46%
-122
- C2 -
1EP1
2
PYRK_LACLM
B:
[7-261]
------
M
T
V
V
S
Q
R
E
V
A
Y
N
I
F
E
M
V
L
K
G
T
L
--
V
D
E
M
D
L
P
G
Q
F
L
H
L
A
V
P
N
G
A
----------------------------
M
-
L
L
R
R
P
I
S
I
S
S
W
D
K
R
A
K
T
C
T
I
L
Y
R
I
-----------
G
-----------------
D
--
E
TT
G
T
Y
K
L
S
-
K
L
E
S
-
G
A
-
K
-
V
D
V
M
G
P
L
G
N
-------
G
-------
F
P
V
A
E
V
-
T
S
T
D
K
I
L
-
I
I
G
G
G
I
G
V
P
P
L
Y
E
L
A
K
Q
L
E
----
K
T
----
G
--
C
Q
--
M
T
I
L
L
G
F
A
S
E
N
V
K
I
L
E
N
E
F
S
N
L
K
--
N
--------
V
--
T
L
K
-
I
-------------
A
T
D
----
D
-----
G
S
Y
G
T
K
G
H
V
G
M
L
-
M
-
N
E
--
I
-----
D
F
----
E
V
D
A
L
Y
T
C
G
A
P
A
M
L
K
--
A
V
A
K
-
K
Y
D
---
Q
L
E
R
L
-
Y
I
S
M
E
S
R
M
A
C
G
I
G
A
C
Y
A
C
V
E
H
D
K
E
D
E
S
H
A
L
K
V
C
E
D
G
P
V
F
L
G
K
Q
L
S
L
29
HHSearch
77.62
46%
-108
* C2 *
1EP3
2
PYRK_LACLM
B:
[4-262]
--
L
Q
E
M
M
T
V
V
S
Q
R
E
V
A
Y
N
I
F
E
M
V
L
K
G
T
L
--
V
D
E
M
D
L
P
G
Q
F
L
H
L
A
V
P
N
G
-----------------------------
A
M
L
L
R
R
P
I
S
I
S
S
W
D
K
R
A
K
T
C
T
I
L
Y
R
I
-----------
G
-----------------
D
ET
T
--
G
T
Y
K
L
S
-
K
L
E
S
-
G
A
-
K
-
V
D
V
M
G
P
L
G
N
-------
G
-------
F
P
V
A
E
V
-
T
S
T
D
K
I
L
-
I
I
G
G
G
I
G
V
P
P
L
Y
E
L
A
K
Q
L
E
----
K
T
----
G
--
C
Q
--
M
T
I
L
L
G
F
A
S
E
N
V
K
I
L
E
N
E
F
S
N
L
K
--
N
V
T
------
L
--
K
---
I
-------------
A
T
D
----
D
-----
G
S
Y
G
T
K
G
H
V
G
M
L
-
M
-
N
E
--
I
-----
D
F
----
E
V
D
A
L
Y
T
C
G
A
P
A
M
L
K
--
A
V
A
K
-
K
Y
D
Q--
L
E
R
-
L
-
Y
I
S
M
E
S
R
M
A
C
G
I
G
A
C
Y
A
C
V
E
H
D
K
E
D
E
S
H
A
L
K
V
C
E
D
G
P
V
F
L
G
K
Q
L
S
L
3
PsiBlast_PDB
77.14
46%
-121
- C2 -
1EP2
2
PYRK_LACLM
B:
[7-261]
------
M
T
V
V
S
Q
R
E
V
A
Y
N
I
F
E
M
V
L
K
G
T
L
--
V
D
E
M
D
L
P
G
Q
F
L
H
L
A
V
P
N
G
A
----------------------------
M
-
L
L
R
R
P
I
S
I
S
S
W
D
K
R
A
K
T
C
T
I
L
Y
R
I
-----------
G
-----------------
D
--
E
TT
G
T
Y
K
L
S
-
K
L
E
S
-
G
A
-
K
-
V
D
V
M
G
P
L
G
N
-------
G
-------
F
P
V
A
E
V
-
T
S
T
D
K
I
L
-
I
I
G
G
G
I
G
V
P
P
L
Y
E
L
A
K
Q
L
E
----
K
T
----
G
--
C
Q
--
M
T
I
L
L
G
F
A
S
E
N
V
K
I
L
E
N
E
F
S
N
L
K
--
N
--------
V
--
T
L
K
-
I
-------------
A
T
D
----
D
-----
G
S
Y
G
T
K
G
H
V
G
M
L
-
M
-
N
E
--
I
-----
D
F
----
E
V
D
A
L
Y
T
C
G
A
P
A
M
L
K
--
A
V
A
K
-
K
Y
D
---
Q
L
E
R
L
-
Y
I
S
M
E
S
R
M
A
C
G
I
G
A
C
Y
A
C
V
E
H
D
K
E
D
E
S
H
A
L
K
V
C
E
D
G
P
V
F
L
G
K
Q
L
S
L
1
PsiBlast_PDB
76.94
46%
-115
- C2 -
1EP3
2
PYRK_LACLM
B:
[8-262]
------
M
T
V
V
S
Q
R
E
V
A
Y
N
I
F
E
M
V
L
K
G
T
L
--
V
D
E
M
D
L
P
G
Q
F
L
H
L
A
V
P
N
G
A
----------------------------
M
-
L
L
R
R
P
I
S
I
S
S
W
D
K
R
A
K
T
C
T
I
L
Y
R
I
-----------
G
-----------------
D
--
E
TT
G
T
Y
K
L
S
-
K
L
E
S
-
G
A
-
K
-
V
D
V
M
G
P
L
G
N
-------
G
-------
F
P
V
A
E
V
-
T
S
T
D
K
I
L
-
I
I
G
G
G
I
G
V
P
P
L
Y
E
L
A
K
Q
L
E
----
K
T
----
G
--
C
Q
--
M
T
I
L
L
G
F
A
S
E
N
V
K
I
L
E
N
E
F
S
N
L
K
--
N
--------
V
--
T
L
K
-
I
-------------
A
T
D
----
D
-----
G
S
Y
G
T
K
G
H
V
G
M
L
-
M
-
N
E
--
I
-----
D
F
----
E
V
D
A
L
Y
T
C
G
A
P
A
M
L
K
--
A
V
A
K
-
K
Y
D
---
Q
L
E
R
L
-
Y
I
S
M
E
S
R
M
A
C
G
I
G
A
C
Y
A
C
V
E
H
D
K
E
D
E
S
H
A
L
K
V
C
E
D
G
P
V
F
L
G
K
Q
L
S
L
5
PsiBlast_PDB
61.50
33%
-104
- C2 -
4YRY
3
PYRKH_THEMA
A:
[9-251]
--------
I
V
K
K
V
K
I
A
E
D
V
F
D
F
W
I
H
S
P
S
--
V
S
K
E
A
R
P
G
Q
F
V
V
I
R
L
H
E
K
G
----------------------------
E
---
R
I
P
L
T
V
A
D
T
K
P
E
E
G
L
F
R
M
V
V
K
V
-----------
V
-----------------
G
--
K
--
T
T
H
E
L
S
-
L
K
K
E
-
G
D
T
I
-
L
D
V
V
G
P
L
G
N
-------
P
----------
S
E
I
-
E
N
Y
G
N
V
L
-
L
V
G
G
G
V
G
I
A
T
L
Y
P
I
A
K
A
L
K
----
E
A
----
G
--
N
N
--
I
T
T
V
L
G
A
R
T
K
D
Y
L
I
M
V
D
E
F
K
E
I
S
--
D
--------
V
--
L
---
L
-------------
V
T
D
----
D
-----
G
S
A
G
M
K
G
V
V
T
D
A
-
M
-
D
K
LF
R
-----
E
R
----
K
F
D
I
C
W
A
V
G
P
T
I
M
M
K
F
C
T
L
K
A
-
R
E
F
---
G
V
P
-
I
-
W
V
S
L
N
P
I
M
V
D
G
T
G
M
C
G
A
C
R
V
-
T
V
S
G
Q
I
K
F
--
A
C
V
D
G
P
E
F
R
G
E
E
V
--
28
HHSearch
61.45
33%
-104
- C2 -
4YLF
2
PYRKH_THEMA
A:
[4-253]
---
T
A
L
N
E
I
V
K
K
V
K
I
A
E
D
V
F
D
F
W
I
H
S
P
S
--
V
S
K
E
A
R
P
G
Q
F
V
V
I
R
L
H
E
-------------------------------
K
G
E
R
I
P
L
T
V
A
D
T
K
P
E
E
G
L
F
R
M
V
V
K
V
-----------
V
-----------------
G
--
K
--
T
T
H
E
L
S
-
L
K
K
E
-
G
D
-
T
I
L
D
V
V
G
P
L
G
N
-------
P
-------
S
E
I
E
N
----
Y
G
N
V
L
-
L
V
G
G
G
V
G
I
A
T
L
Y
P
I
A
K
A
L
K
----
E
A
----
G
--
N
N
--
I
T
T
V
L
G
A
R
T
K
D
Y
L
I
M
V
D
E
F
K
E
I
S
--
D
--------
V
--
L
---
L
-------------
V
T
D
----
D
-----
G
S
A
G
M
K
G
V
V
T
D
A
-
M
-
D
K
--
L
FR---
E
R
----
K
F
D
I
C
W
A
V
G
P
T
I
M
M
K
--
F
C
T
L
-
K
A
R
EF-
G
V
P
-
I
-
W
V
S
L
N
P
I
M
V
D
G
T
G
M
C
G
A
C
R
V
T
V
S
-
G
--
Q
I
K
F
A
C
V
D
G
P
E
F
R
G
E
E
V
D
W
4
PsiBlast_PDB
61.39
33%
-104
- C2 -
4YLF
2
PYRKH_THEMA
A:
[9-251]
--------
I
V
K
K
V
K
I
A
E
D
V
F
D
F
W
I
H
S
P
S
--
V
S
K
E
A
R
P
G
Q
F
V
V
I
R
L
H
E
K
G
----------------------------
E
---
R
I
P
L
T
V
A
D
T
K
P
E
E
G
L
F
R
M
V
V
K
V
-----------
V
-----------------
G
--
K
--
T
T
H
E
L
S
-
L
K
K
E
-
G
D
T
I
-
L
D
V
V
G
P
L
G
N
-------
P
----------
S
E
I
-
E
N
Y
G
N
V
L
-
L
V
G
G
G
V
G
I
A
T
L
Y
P
I
A
K
A
L
K
----
E
A
----
G
--
N
N
--
I
T
T
V
L
G
A
R
T
K
D
Y
L
I
M
V
D
E
F
K
E
I
S
--
D
--------
V
--
L
---
L
-------------
V
T
D
----
D
-----
G
S
A
G
M
K
G
V
V
T
D
A
-
M
-
D
K
LF
R
-----
E
R
----
K
F
D
I
C
W
A
V
G
P
T
I
M
M
K
F
C
T
L
K
A
-
R
E
F
---
G
V
P
-
I
-
W
V
S
L
N
P
I
M
V
D
G
T
G
M
C
G
A
C
R
V
-
T
V
S
G
Q
I
K
F
--
A
C
V
D
G
P
E
F
R
G
E
E
V
--
45
HHSearch
59.82
25%
-115
- C2 -
2R6H
4
?
A:
[8-280]
--
K
E
W
E
C
E
V
L
S
N
K
N
V
S
T
F
I
K
E
F
V
V
K
L
P
E
G-
E
T
M
N
F
K
S
G
S
Y
A
Q
I
K
I
P
K
Y
N
I
R
YAD
Y
D
I
Q
DRFR
G
D
W
D
K
M
DAWS
L
T
C
K
N
E
E
E
T
V
R
A
Y
S
M
A
N
Y
P
A
E
G
N
I
I
T
L
N
V
R
I
-----------
A
TPPFDRAANKWKAGIKP
G
--
I
--
S
S
S
Y
I
F
-
S
L
K
P
-
G
D
-
K
-
V
M
M
S
G
P
Y
G
D
---------------
F
H
I
Q
D
T
---
D
A
E
M
L
-
Y
I
G
G
G
A
G
M
A
P
L
R
A
Q
I
L
H
L
F
----
R
T
LKT-
G
--
R
K
--
V
S
Y
W
Y
G
A
R
S
K
N
E
I
F
Y
E
E
D
F
R
E
I
E
--
R
E
F
PN
F
K
--
F
--
H
---
I
A
------------
L
S
D
----
P
QPED-
N
W
T
G
Y
V
G
F
I
H
Q
V
-
I
Y
D
N
--
Y
LKDHD
A
P
----
E
D
I
E
Y
Y
M
C
G
P
G
P
M
A
N
--
A
V
K
G
-
M
L
E
N
L
-
G
V
P
-------------------------------------------------
22
PsiBlast_CBE
58.39
33%
-103
- C2 -
4YLF
3
PYRKH_THEMA
C:
[9-251]
--------
I
V
K
K
V
K
I
A
E
D
V
F
D
F
W
I
H
S
P
S
--
V
S
K
E
A
R
P
G
Q
F
V
V
I
R
L
H
E
K
G
----------------------------
E
---
R
I
P
L
T
V
A
D
T
K
P
E
E
G
L
F
R
M
V
V
K
V
-----------
V
-----------------
G
--
K
--
T
T
H
E
L
S
-
L
K
K
E
-
G
D
T
I
-
L
D
V
V
G
P
L
G
N
-------
P
----------
S
E
I
-
E
N
Y
G
N
V
L
-
L
V
G
G
G
V
G
I
A
T
L
Y
P
I
A
K
A
L
K
----
E
A
----
G
--
N
N
--
I
T
T
V
L
G
A
R
T
K
D
Y
L
I
M
V
D
E
F
K
E
I
S
--
D
--------
V
--
L
---
L
-------------
V
T
D
----
D
-----
G
S
A
G
M
K
G
------------------------
K
F
D
I
C
W
A
V
G
P
T
I
M
M
K
F
C
T
L
K
A
-
R
E
F
---
G
V
P
-
I
-
W
V
S
L
N
P
I
M
V
D
G
T
G
M
C
G
A
C
R
V
-
T
V
S
G
Q
I
K
F
--
A
C
V
D
G
P
E
F
R
G
E
E
V
--
21
PsiBlast_CBE
57.96
33%
-98
- C2 -
4YRY
2
PYRKH_THEMA
C:
[9-251]
--------
I
V
K
K
V
K
I
A
E
D
V
F
D
F
W
I
H
S
P
S
--
V
S
K
E
A
R
P
G
Q
F
V
V
I
R
L
H
E
K
G
----------------------------
E
---
R
I
P
L
T
V
A
D
T
K
P
E
E
G
L
F
R
M
V
V
K
V
-----------
V
-----------------
G
--
K
--
T
T
H
E
L
S
-
L
K
K
E
-
G
D
T
I
-
L
D
V
V
G
P
L
G
N
-------
P
----------
S
E
I
-
E
N
Y
G
N
V
L
-
L
V
G
G
G
V
G
I
A
T
L
Y
P
I
A
K
A
L
K
----
E
A
----
G
--
N
N
--
I
T
T
V
L
G
A
R
T
K
D
Y
L
I
M
V
D
E
F
K
E
I
S
--
D
--------
V
--
L
---
L
-------------
V
T
D
----
D
-----
G
S
A
G
M
K
G
V
V
T
D
--------
R
-----
E
R
----
K
F
D
I
C
W
A
V
G
P
T
I
M
M
K
F
C
T
------
F
---
G
V
P
-
I
-
W
V
S
L
N
P
I
M
V
D
G
T
G
M
C
G
A
C
R
V
-
T
V
S
G
Q
I
K
F
--
A
C
V
D
G
P
E
F
R
G
E
E
V
--
31
HHSearch
52.72
20%
-113
- C2 -
4P6V
1
NQRF_VIBCH
F:
[132-405]
---
K
W
E
C
T
V
I
S
N
D
N
K
A
T
F
I
K
E
L
K
L
A
I
P
D
G-
E
S
V
P
F
R
A
G
G
Y
I
Q
I
E
A
P
A
H
H
V
K
YADFDVPEKYR
G
D
W
D
K
F
NLFR
Y
E
S
K
V
D
E
P
I
I
R
A
Y
S
M
A
N
Y
P
E
E
F
G
I
I
M
L
N
V
R
I
ATPPPNNPNVP
P
-----------------
G
--
Q
--
M
S
S
Y
I
W
-
S
L
K
A
-
G
D
-
K
-
C
T
I
S
G
P
F
G
E
-------
F
-------
F
A
K
D
-
T
---
D
A
E
M
V
-
F
I
G
G
G
A
G
M
A
P
M
R
S
H
I
F
D
Q
L
----
K
R
LKS-
K
--
R
K
--
M
S
Y
W
Y
G
A
R
S
K
R
E
M
F
Y
V
E
D
F
D
G
L
A
--
A
E
N
DN----
F
V
W
H
---
C
A
------------
L
S
D
PQPE
D
-----
N
W
T
G
Y
T
G
F
I
H
N
V
-
L
Y
E
N
--
Y
LKDHE
A
P
----
E
D
C
E
Y
Y
M
C
G
P
P
M
M
N
A
--
A
V
I
N
-
M
L
K
N
L
-
G
V
E
E
E
-
N
I
L
L
D
D
----------------------------------------
39
HHSearch
51.71
17%
-135
- C2 -
2CND
1
A:
[11-263]
--
G
R
I
H
C
R
L
V
A
K
K
E
L
S
R
D
V
R
L
F
R
F
S
L
P
S
PD
Q
V
L
G
L
P
I
G
K
H
I
F
V
C
A
T
I
E
-----------------------------
G
K
L
C
M
R
A
Y
T
P
T
S
M
V
D
E
I
G
H
F
D
L
L
V
K
V
-----------
Y
FKNEHPKFPNG------
G
--
L
--
M
T
Q
Y
L
D
-
S
L
P
V
-
G
S
-
Y
-
I
D
V
K
G
P
L
G
H
-------
V
EYTGRG
S
F
V
I
N
G
K
Q
R
N
A
R
R
L
A
-
M
I
C
G
G
S
G
I
T
P
M
Y
Q
I
I
Q
A
V
L
----
R
D
QPED
H
--
T
E
--
M
H
L
V
Y
A
N
R
T
E
D
D
I
L
L
R
D
E
L
D
R
W
A
--
A
E
YPDR---
L
--
K
V
W
-
Y
V
------------
I
D
Q
----
V
KRPEE
G
W
K
Y
S
V
G
F
V
T
E
A
V
L
-
R
E
--
H
VPE--
G
G
----
D
D
T
L
A
L
A
C
G
P
P
P
M
I
Q
--
F
A
I
S
P
N
L
E
K
M
-
K
Y
D
-
M
-----------------------------------------------
9
PsiBlast_PDB
51.25
27%
-194
- C2 -
1KRH
4
BENC_ACIAD
A:
[179-317]
------------------------------------------------------------------------------------------------------------------------------------
G
--
K
--
M
S
E
Y
L
S
-
V
Q
A
K
A
G
D
-
K
-
M
S
F
T
G
P
F
G
S
---------------
F
Y
L
R
D
V
-
K
--
R
P
V
L
-
M
L
A
G
G
T
G
I
A
P
F
L
S
M
L
Q
V
L
E
----
Q
K
----
G
--
S
E
H
P
V
R
L
V
F
G
V
T
Q
D
C
D
L
V
A
L
E
Q
L
D
A
L
Q
--
Q
K
L
P
W
F
E
Y
R
T
--
V
---
V
-------------
A
H
A
----
E
-----
S
Q
H
E
R
K
G
Y
V
T
G
H
-
I
-
E
Y
--
D
-----
W
L
NGG-
E
V
D
V
Y
L
-
C
G
P
V
P
M
V
E
--
A
V
R
------------------------------------------------------------
37
HHSearch
51.08
20%
-101
- C2 -
4U9U
4
NQRF_VIBCH
A:
[4-278]
--
K
K
W
E
C
T
V
I
S
N
D
N
K
A
T
F
I
K
E
L
K
L
A
I
P
D
G-
E
S
V
P
F
R
A
G
G
Y
I
Q
I
E
A
P
A
H
H
V
K
YADFDVPEKYR
G
D
W
D
K
F
NLFR
Y
E
S
K
V
D
E
P
I
I
R
A
Y
S
M
A
N
Y
P
E
E
F
G
I
I
M
L
N
V
R
I
-----------
A
TPPPNNPNVPP------
G
--
Q
--
M
S
S
Y
I
W
-
S
L
K
A
-
G
D
-
K
-
C
T
I
S
G
P
F
G
E
-------
F
-------
F
A
K
D
T
----
D
A
E
M
V
-
F
I
G
G
G
A
G
M
A
P
M
R
S
H
I
F
D
Q
L
----
K
R
LKS-
K
--
R
K
--
M
S
Y
W
Y
G
A
R
S
K
R
E
M
F
Y
V
E
D
F
D
G
L
A
--
A
E
N
DN
F
V
--
W
--
H
---
C
A
------------
L
S
D
PQPE
D
-----
N
W
T
G
Y
T
G
F
I
H
N
V
-
L
Y
E
N
--
Y
LKDHE
A
P
----
E
D
C
E
Y
Y
M
C
G
P
P
M
M
N
A
--
A
V
I
N
-
M
L
K
N
L
-
G
V
E
-
E
E
N
I
L
L
D
D
----------------------------------------
11
PsiBlast_PDB
49.22
22%
-206
- C2 -
2CND
1
A:
[98-249]
-------------------------------------------------------------------------------------------------------------------------------------------
T
Q
Y
L
D
-
S
L
P
V
-
G
S
-
Y
-
I
D
V
K
G
P
L
G
H
VEYTGRG
S
-------
F
V
I
N
G
K
-
Q
R
N
A
R
R
L
A
M
I
C
G
G
S
G
I
T
P
M
Y
Q
I
I
Q
A
V
L
R
D
QP
E
D
----
H
--
T
E
--
M
H
L
V
Y
A
N
R
T
E
D
D
I
L
L
R
D
E
L
D
R
W
A
--
A
--------
E
--
Y
---
P
DR
L
K
V
W
Y
V
I
DQVK
R
P
E
----
E
-----
G
W
K
Y
S
V
G
F
V
T
E
A
-
V
-
L
R
--
E
-----
H
V
PEGG
D
D
T
L
A
L
A
C
G
P
P
P
M
I
Q
-----------------------------------------------------------------
34
HHSearch
48.59
22%
-106
- C2 -
4WQM
4
TMOF_PSEME
A:
[102-323]
---
R
F
S
T
R
V
V
S
K
R
F
L
S
D
E
M
F
E
L
R
L
E
A
E
Q
---
K
V
V
F
S
P
G
Q
Y
F
M
V
D
V
P
E
--------------------------------
L
G
T
R
A
Y
S
A
A
N
P
V
D
-
G
N
T
L
T
L
I
V
K
A
-----------
V
PN---------------
G
--
K
--
V
S
C
A
L
A
-
N
E
-
T
-
I
E
-
T
-
L
Q
L
D
G
P
Y
G
L
-------
S
-------
V
L
K
T
A
D
---
E
T
Q
S
V
-
F
I
A
G
G
S
G
I
A
P
M
V
S
M
V
N
T
L
I
----
A
Q
----
G
YE
K
P
--
I
T
V
F
Y
G
S
R
L
E
A
E
L
E
A
A
E
T
L
F
G
W
K
--
E
N
L
K
L
----
I
--
N
---
V
-------------
S
S
S
VVGN
S
-----
E
S
S
Y
P
T
G
Y
V
H
E
I
-
I
-
P
E
--
Y
ME---
G
L
----
L
G
A
E
F
Y
L
C
G
P
P
Q
M
I
N
--
S
V
Q
K
-
L
L
M
IEN
K
V
P
-
F
E
A
I
H
F
D
-----------------------------------------
10
PsiBlast_PDB
48.39
22%
-213
- C2 -
1CNF
2
A:
[98-249]
-------------------------------------------------------------------------------------------------------------------------------------------
T
Q
Y
L
D
-
S
L
P
V
-
G
S
-
Y
-
I
D
V
K
G
P
L
G
H
VEYTGRG
S
-------
F
V
I
N
G
K
-
Q
R
N
A
R
R
L
A
M
I
C
G
G
S
G
I
T
P
M
Y
Q
I
I
Q
A
V
L
R
D
QP
E
D
----
H
--
T
E
--
M
H
L
V
Y
A
N
R
T
E
D
D
I
L
L
R
D
E
L
D
R
W
A
--
A
--------
E
--
Y
---
P
D
R
L
K
V
W
Y
V
I
DQVK
R
P
E
----
E
-----
G
W
K
Y
S
V
G
F
V
T
E
A
-
V
-
L
R
--
E
-----
H
V
PEGG
D
D
T
L
A
L
A
C
G
P
P
P
M
I
Q
-----------------------------------------------------------------
33
HHSearch
47.24
19%
-111
- C2 -
1KRH
4
BENC_ACIAD
A:
[108-334]
---
H
F
E
G
T
L
A
R
V
E
N
L
S
D
S
T
I
T
F
D
I
Q
L
D
D
GQ
P
D
I
H
F
L
A
G
Q
Y
V
N
V
T
L
P
G
-------------------------------
T
T
E
T
R
S
Y
S
F
S
S
Q
P
G
-
N
R
L
T
G
F
V
V
R
N
-----------
V
PQ---------------
G
--
K
--
M
S
E
Y
L
S
V
Q
A
K
A
-
G
D
-
K
-
M
S
F
T
G
P
F
G
S
-------
F
-------
Y
L
R
-
D
V
---
K
R
P
V
L
-
M
L
A
G
G
T
G
I
A
P
F
L
S
M
L
Q
V
L
E
----
Q
K
GS--
E
--
H
P
--
V
R
L
V
F
G
V
T
Q
D
C
D
L
V
A
L
E
Q
L
D
A
L
Q
--
Q
K
L
P
W----
F
--
E
Y
R
T
V
-------------
V
A
H
A---
E
-----
S
Q
H
E
R
K
G
Y
V
T
G
H
-
I
-
E
Y
--
D
WL---
N
G
----
G
E
V
D
V
Y
L
C
G
P
V
P
M
V
E
--
A
V
R
S
-
W
L
D
T
Q
-
G
I
Q
P
A
-
N
F
L
F
E
K
----------------------------------------
41
HHSearch
46.85
17%
-137
- C2 -
1QFJ
1
FRE_ECOLI
A:
[2-220]
---
T
L
S
C
K
V
T
S
V
E
A
I
T
D
T
V
Y
R
V
R
I
V
P
D
---
A
A
F
S
F
R
A
G
Q
Y
L
M
V
V
M
D
E
--------------------------------
R
D
K
R
P
F
S
M
A
S
T
P
D
E
K
G
F
I
E
L
H
I
G
------------------------------------
Y
A
K
A
V
M
D
R
I
L
K
-
D
H
-
Q
-
I
V
V
D
I
P
H
G
E
-------
A
-------
W
L
R
D
D
E
---
E
R
P
M
I
-
L
I
A
G
G
T
G
F
S
Y
A
R
S
I
L
L
T
A
L
----
A
R
NP--
N
--
R
D
--
I
T
I
Y
W
G
G
R
E
E
Q
H
L
Y
D
L
C
E
L
E
A
L
S
--
L
K
H
P
G
L
Q
--
V
--
V
---
P
V
------------
V
E
Q
PE--
A
-----
G
W
R
G
R
T
G
T
V
L
T
A
V
L
-
Q
D
--
H
G----
T
L
----
A
E
H
D
I
Y
I
A
G
R
F
E
M
A
K
--
I
A
R
D
-
L
F
C
S
ER
N
A
R
-------------------------------------------------