@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0070: (2015-11-28 )
MDWLLVSILSIIFVLLILSFLFSGAEIGLTSVSRSRVNKLKLDGNKRAKIIDHLLNKKELTIGTILLGNTIINITCSVLFTAIFINLFGNESVFLSTIVMTFCILLFCEVLPKTYAMQNPEKFTSFSAYFVLFFVKIFSPLTLGIQFIVNFILKLCGFHKNREAISAADAMRNMIALHRSEGTMLQQDLDMLSSILDLAETEISEIMTHRRNLFSLDIDRNKEELIKEILTSSHSRVPLWQKELDNIVGVVHVKNLINALREKDNKIEEVDIAQVMSKPCFLPESTPLSVQLHNFRKNRKHLAFVIDEYGALQGIVTLEDILEEIVGEISDEHDLITENFIKKMSDNVYHIEGKSTIRDINRQLHWDLPDEEATTLAGMIVNEIERIPDEGEEFSMFGFYFRILKKDKNIITVIEVQVKTDNTVTAID
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180---........-190.......200.......210.....----..220........230..-.....240.......250.......260.......270....----.-..280........290.......300....--------..--------.310.......320....-...330.......340.......350.......360.......370.......380.......390.......400.......410.......420......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
D
W
L
L
V
S
I
L
S
I
I
F
V
L
L
I
L
S
F
L
FSGAEI
G
L
T
S
VSRSR
V
N
K
L
KLDGN
K
R
A
K
I
I
D
H
L
LNKKE
L
T
I
G
T
I
L
LGN
T
I
I
N
I
T
C
S
V
L
F
T
A
I
F
I
N
LFGN
E
S
V
F
L
S
T
I
V
M
T
F
C
I
L
L
F
C
E
V
L
P
K
T
YAMQ
N
P
E
K
F
T
S
F
S
A
Y
F
V
L
F
F
V
K
I
F
S
P
L
T
L
G
I
Q
F
I
V
N
F
I
L
K
LCGFHKNR
E
A
I
S
A
A
D
A
M
R
N
M
I
A
L
HRSE----G
T
M
L
Q
Q
D
L
-
D
M
L
S
S
I
L
D
L
A
E
T
E
I
S
E
I
M
T
HRRN
L
F
S
LD----IDR
N
-
K
E
E
L
I
K
E
I
L
TSSH-SRV
P
L
W
Q
K
E
L
D
N
I
V
G
V
V
H
V
K
N
L
I
N
A
L
R
EKDNKI
E
E
V
D
I
A
Q
V
M
----S-KPC-FLPEST
P
L
S
V
Q
L
H
N
FRKNR
K
H
L
A
F
V
I
--------DE--------YGALQ
G
I
V
T
L
E
D
I
L
E
E
I
V
-
G
EISDEH
D
L
I
T
E
N
F
I
K
K
MSD
N
V
Y
H
IEG
K
S
T
I
R
D
I
N
R
QLHWDLP
D
E
E
A
T
T
L
A
G
M
I
V
N
E
I
E
RIPDEGEE
F
S
M
F
G
F
Y
F
R
I
L
KKDK
N
I
I
T
V
I
E
V
Q
V
KTD
N
T
V
TAID
1
PsiBlast_PDB
93.15
29%
-91
* C1 *
4HG0
1
CORC_ECOLI
A:
[51-282]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
D
T
R
D
M
L
E
G
V
M
D
I
A
D
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
----
R
N
Q
T
-
L
D
E
C
L
D
V
I
I
E
S
A
H
-
S
R
F
P
V
I
S
E
D
K
D
H
I
E
G
I
L
M
A
K
D
L
L
P
F
M
R
---
S
D
A
E
A
F
S
M
D
K
V
L
----
R
-
Q
A
V
-
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
--------
D
E
--------
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
V
-
G
E
I
E
D
E
Y
D
E
E
D
D
I
D
F
R
Q
L
S
R
H
T
W
T
V
R
A
L
A
S
I
E
D
F
N
E
A
F
G
T
H
F
S
D
E
E
V
D
T
I
G
G
L
V
M
Q
A
F
G
H
L
P
A
R
G
E
T
I
D
I
D
G
Y
Q
F
K
V
A
M
A
D
S
R
R
I
I
Q
V
H
V
K
I
P
---------
3
PsiBlast_PDB
72.32
35%
-113
- C1 -
3HF7
1
?
A:
[4-127]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
N
D
I
M
V
P
R
N
E
I
V
G
I
D
----
I
N
D
D
-
W
K
S
I
V
R
Q
L
T
H
S
P
H
-
G
R
I
V
L
Y
R
D
S
L
D
D
A
I
S
M
L
R
V
R
E
A
Y
R
L
M
T
E
K
K
E
F
T
K
E
I
-
M
L
R
A
A
----
D
-
E
I
Y
-
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
--------
D
E
--------
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
-
G
-----------------------------------------------------------------------------------------------------
57
Fugue
71.31
34%
-109
- C1 -
3HF7
1
?
A:
[1-127]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
S
V
N
D
I
M
V
P
R
N
E
I
V
G
I
D
----
I
N
D
D
-
W
K
S
I
V
R
Q
L
T
H
S
P
H
-
G
R
I
V
L
Y
R
D
S
L
D
D
A
I
S
M
L
R
V
R
E
A
Y
R
L
M
T
E
K
-
K
E
F
T
K
E
I
M
L
R
A
A
----
D
-
E
I
Y
-
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
--------
D
E
--------
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
-
G
-----------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
69.75
34%
-86
- C1 -
3LV9
1
?
A:
[18-147]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
F
E
E
K
K
I
R
E
I
M
V
P
R
T
D
M
V
C
I
-----
Y
E
S
D
-
S
E
E
K
I
L
A
I
L
K
E
E
G
V
T
R
Y
P
V
C
R
K
N
K
D
D
I
L
G
F
V
H
I
R
D
L
Y
N
Q
-
K
I
N
E
N
K
I
E
---
L
E
E
I
L
----
R
-
D
I
I
-
Y
I
S
E
N
L
T
I
D
K
A
L
E
R
I
R
K
E
K
L
Q
L
A
I
V
V
--------
D
E
--------
Y
G
G
T
S
G
V
V
T
I
E
D
I
L
E
E
I
V
-
G
E
I
---------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
69.71
29%
-97
- C1 -
3OI8
4
?
A:
[4-156]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
E
D
V
L
N
L
L
R
Q
A
H
E
Q
E
VFD
A
D
T
L
L
R
------
L
E
K
V
L
D
F
S
D
L
E
V
R
D
A
M
I
T
R
S
R
M
N
V
L
K
----
E
N
D
S
-
I
E
R
I
T
A
Y
V
I
D
T
A
H
-
S
R
F
P
V
I
G
E
D
K
D
E
V
L
G
I
L
H
A
K
D
L
L
K
Y
M
F
N
P
----
E
Q
F
H
L
K
S
I
L
----
R
-
P
A
V
-
F
V
P
E
G
K
S
L
T
A
L
L
K
E
F
R
E
Q
R
N
H
M
A
I
V
I
--------
D
E
--------
Y
G
G
T
S
G
L
V
T
F
E
D
I
I
E
----------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
69.33
38%
-85
- C1 -
3JTF
4
?
A:
[4-128]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
T
V
A
D
I
M
V
P
R
S
R
M
D
L
L
D
----
I
S
Q
P
-
L
P
Q
L
L
A
T
I
I
E
T
A
H
-
S
R
F
P
V
Y
E
D
D
R
D
N
I
I
G
I
L
L
A
K
D
L
L
R
Y
M
L
E
P
-----
A
L
D
I
R
S
L
V
----
R
-
P
A
V
-
F
I
P
E
V
K
R
L
N
V
L
L
R
E
F
R
A
S
R
N
H
L
A
I
V
I
--------
D
E
---------
G
G
I
S
G
L
V
T
M
E
D
V
L
E
Q
I
V
-
G
D
I
---------------------------------------------------------------------------------------------------
51
HHSearch
69.32
36%
-100
- C1 -
3HF7
1
?
A:
[2-127]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
V
N
D
I
M
V
P
R
N
E
I
V
G
I
D
----
I
N
D
D
-
W
K
S
I
V
R
Q
L
T
H
S
P
H
-
G
R
I
V
L
Y
R
D
S
L
D
D
A
I
S
M
L
R
V
R
E
A
Y
R
L
M
T
E
K
K
-----
E
F
T
K
E
I
M
L
R
A
A
D
-
E
I
Y
-
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
--------
D
E
--------
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
-
G
-----------------------------------------------------------------------------------------------------
36
HHSearch
69.01
28%
-92
- C1 -
3OI8
4
?
A:
[3-156]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
A
E
D
V
L
N
L
L
R
Q
A
H
E
Q
----
E
V
F
D
A
D
T
L
-
L
R
L
E
K
V
L
D
F
S
D
L
E
V
R
D
A
M
I
T
R
S
R
M
N
V
L
K
----
E
N
D
S
-
I
E
R
I
T
A
Y
V
I
D
T
A
H
-
S
R
F
P
V
I
G
E
D
K
D
E
V
L
G
I
L
H
A
K
D
L
L
K
Y
M
F
N
P
E
----
Q
F
H
L
K
S
I
L
----
R
-
P
A
V
-
F
V
P
E
G
K
S
L
T
A
L
L
K
E
F
R
E
Q
R
N
H
M
A
I
V
I
--------
D
E
--------
Y
G
G
T
S
G
L
V
T
F
E
D
I
I
E
----------------------------------------------------------------------------------------------------------
38
HHSearch
68.88
30%
-88
- C1 -
3LV9
1
?
A:
[18-147]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
F
E
E
K
K
I
R
E
I
M
V
P
R
T
D
M
V
C
I
Y
----
E
S
D
S
-
E
E
K
I
L
A
I
L
K
E
E
G
V
-
T
R
Y
P
V
C
R
K
N
K
D
D
I
L
G
F
V
H
I
R
D
L
Y
N
Q
K
I
N
E
N
----
K
I
E
L
E
E
I
L
----
R
-
D
I
I
-
Y
I
S
E
N
L
T
I
D
K
A
L
E
R
I
R
K
E
K
L
Q
L
A
I
V
V
--------
D
E
--------
Y
G
G
T
S
G
V
V
T
I
E
D
I
L
E
E
I
V
-
G
E
I
---------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
68.83
31%
-73
- C1 -
4IYS
-
A:
[2-156]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
-
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
GEAI
L
D
F
N
-
T
---
M
S
E
I
M
E
S
G
Y
-
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
--
A
F
V
D
P
D
D
C
T
P
L
K
T
I
T
K
F
Y
----
N
-
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
VNNEGE-
D
P
--------
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
K
S
E
I
L
D
E
------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
68.81
31%
-72
- C1 -
4IY0
4
A:
[1-152]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
E
L
-
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
GEAI
L
D
F
N
-
T
---
M
S
E
I
M
E
S
G
Y
-
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
--
A
F
V
D
P
D
D
C
T
P
L
K
T
I
T
K
F
Y
----
N
-
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
--------
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
K
S
E
----------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
68.58
30%
-81
- C1 -
4P1G
1
A:
[2-149]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
-
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
GEAI
L
D
F
N
-
T
---
M
S
E
I
M
E
S
G
Y
-
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
--
A
F
V
D
P
D
D
C
T
P
L
K
T
I
T
K
F
Y
----
N
-
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
--------
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
-
K
S
E
---------------------------------------------------------------------------------------------------
59
Fugue
68.55
29%
-63
- C1 -
4IY4
-
CNNM2_HUMAN
A:
[1-152]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
E
L
-
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
----
G
E
A
I
L
D
F
N
T
M
S
E
I
M
E
S
G
Y
-
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
--
A
F
V
D
P
D
D
C
T
P
L
K
T
I
T
K
F
Y
----
N
-
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
--------
R
V
N
NEGE
G
D
P
F
Y
E
V
L
G
I
V
I
L
E
D
V
I
E
E
I
I
-
K
S
E
---------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
68.32
30%
-73
- C1 -
4IY4
-
CNNM2_HUMAN
A:
[1-152]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
E
L
-
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
GEAI
L
D
F
N
-
T
---
M
S
E
I
M
E
S
G
Y
-
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
--
A
F
V
D
P
D
D
C
T
P
L
K
T
I
T
K
F
Y
----
N
-
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
--------
F
Y
E
V
L
G
I
V
I
L
E
D
V
I
E
E
I
I
K
S
E
----------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
68.06
30%
-80
- C1 -
4P1O
2
CNNM2_MOUSE
A:
[2-149]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
-
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
GEAI
L
D
F
N
-
T
---
M
S
E
I
M
E
S
G
Y
-
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
--
A
F
V
D
P
D
D
C
T
P
L
K
T
I
T
K
F
Y
----
N
-
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
VNNEGE
G
D
P
--------
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
-
K
S
E
---------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
67.29
30%
-72
- C1 -
4IY2
-
CNNM2_HUMAN
A:
[2-152]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
-
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
GEAI
L
D
F
N
-
T
---
M
S
E
I
M
E
S
G
Y
-
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
--
A
F
V
D
P
D
D
C
T
P
L
K
T
I
T
K
F
Y
----
N
-
H
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
--------
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
K
S
E
----------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
67.01
29%
-86
- C1 -
3LHH
1
?
A:
[43-165]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
S
L
M
V
P
R
S
D
I
V
F
L
D
----
L
N
L
P
-
L
D
A
N
L
R
T
V
M
Q
S
P
H
-
S
R
F
P
V
C
R
N
N
V
D
D
M
V
G
I
I
S
A
K
Q
L
L
S
E
S
I
A
G
E
-
R
L
E
L
V
D
L
V
---------
K
N
C
N
F
V
P
N
S
L
S
G
M
E
L
L
E
H
F
R
T
T
G
S
Q
M
V
F
V
V
--------
D
E
--------
Y
G
D
L
K
G
L
V
T
L
Q
D
M
M
D
A
L
T
-
G
E
F
F
--------------------------------------------------------------------------------------------------
37
HHSearch
66.91
27%
-81
- C1 -
3OCM
7
?
A:
[18-164]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
G
V
E
E
R
-
N
M
V
S
G
V
L
T
L
A
E
R
S
I
R
S
I
M
T
P
R
T
D
V
S
W
V
N
----
I
D
D
D
-
A
A
T
I
R
Q
Q
L
T
A
A
P
H
-
S
F
F
P
V
C
R
G
S
L
D
E
V
V
G
I
G
R
A
K
D
L
V
A
D
L
I
T
E
------
G
R
V
R
R
N
R
----
L
R
D
P
I
-
I
V
H
E
S
I
G
I
L
R
L
M
D
T
L
K
R
S
R
G
Q
L
V
L
V
A
--------
D
E
--------
F
G
A
I
E
G
L
V
T
P
I
D
V
F
E
A
I
A
-
G
E
F
P
D
E
D
E
L
P
--------------------------------------------------------------------------------------------
48
HHSearch
66.58
36%
-77
- C1 -
3LFR
2
?
A:
[3-125]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
V
R
D
I
M
V
P
R
S
Q
M
I
S
I
K
----
A
T
Q
T
-
P
R
E
F
L
P
A
V
I
D
A
A
H
-
S
R
Y
P
V
I
G
E
S
H
D
D
V
L
G
V
L
L
A
K
D
L
L
P
L
I
L
K
A
D
G
--
D
S
D
D
V
K
K
L
L
----
R
-
P
A
T
-
F
V
P
E
S
K
R
L
N
V
L
L
R
E
F
R
A
N
H
N
H
M
A
I
V
I
--------
D
E
--------
Y
G
G
V
A
G
L
V
T
I
E
D
V
L
E
Q
I
--------------------------------------------------------------------------------------------------------
49
HHSearch
65.87
35%
-80
- C1 -
3NQR
1
CORC_SALTY
A:
[3-124]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
----
R
N
Q
T
-
L
D
E
C
L
D
V
I
I
E
S
A
H
-
S
R
F
P
V
I
S
E
D
K
D
H
I
E
G
I
L
M
A
K
D
L
L
P
F
M
R
S
D
A
---
E
A
F
S
M
D
K
V
L
----
R
-
T
A
V
-
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
--------
D
E
--------
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
--------------------------------------------------------------------------------------------------------