@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0134: (2015-11-28 )
MIRKIRNLKGAYKIREFLEEKLKNIGDNIAASSVDDEDVGATTSSKKKKPATGKPTEQVILQIDDKLELGSKPDLRDSPRLS
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------........--.10....--....20...--------------.....30.-..-----.....40-........-------50..----...--.----..60---....---....-.70........80.---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MI
R
K
I
R
N
L
--
K
G
A
Y
K
I
R
--
E
F
L
E
E
K
L
K
N
--------------IG
D
N
IAAS-SV-----DDEDVGA-TTSSKKKK-------PATG----KP
T
--
E
----
Q
V
I
----
L
Q
ID---DKLE-LGSKPDLRDSPRLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
64.39
25%
18
- C4 -
3W3W
1
IMB3_YEAST
A:
[3-1077]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALP
E
E
V
N
R
T
L
L
Q
I
V
Q
A
F
--
A
S
D
N
Q
I
R
--
S
V
A
E
K
A
L
S
E
EWITENN
I
E
Y
L
L
T
F
L
A
E
Q
A
A
F
S
-
Q
-------
D
T
T
V
A
A
-
L
S
A
V
L
F
R
K
-------
L
A
L
K
----
A
P
I
--
T
HIR
K
E
V
L
----
A
Q
I
R
---
S
S
L
L
-
K
G
F
L
S
E
R
A
D
S
I
R
H
K
L
S
D
A
I
A
E
C
VQDDLPAW
P
E
L
L
Q
A
L
I
E
S
L
K
SGN
P
N
F
R
E
S
S
F
R
I
L
T
T
V
P
Y
L
I
T
A
VD
I
N
S
I
L
P
I
F
Q
S
G
F
T
DAS
D
N
V
K
I
A
A
V
T
A
F
V
G
Y
F
K
Q
LPKSEWSKLGIL
L
P
S
L
L
N
S
L
P
R
F
L
D
D
GK
D
D
A
L
A
S
V
F
E
S
L
I
E
L
V
E
L
APKLFKDM
F
D
Q
I
I
Q
F
T
D
M
V
I
K
NKDLEP
P
A
R
T
T
A
L
E
L
L
T
V
F
S
E
N
A
P
Q
M
C
K
S
N
Q
N
Y
G
Q
T
L
V
M
V
T
L
I
M
M
T
EVSIDDDDA
A
E
W
I
E
SDDTDDEEE
V
T
Y
D
H
A
R
Q
A
L
D
R
V
A
L
K
LGGEYL
A
A
P
L
F
Q
Y
L
Q
Q
M
I
T
STE
W
R
E
R
F
A
A
M
M
A
L
S
S
A
AEGCA
D
V
L
I
G
E
I
P
K
I
L
D
M
V
I
P
L
I
NDPH
P
R
V
Q
Y
G
C
C
N
V
L
G
Q
I
S
T
D
F
S
P
F
I
Q
R
T
A
H
D
R
I
L
P
A
L
I
S
K
L
TSECT
S
R
V
Q
T
H
A
A
A
A
L
V
N
F
S
E
FASKDILEPY
L
D
S
L
L
T
N
L
L
V
L
L
Q
SNK
L
Y
V
Q
E
Q
A
L
T
T
I
A
F
I
A
E
A
A
KNKFIKYYDTL
M
P
L
L
L
N
V
L
K
VN
S
V
L
K
G
K
C
M
E
C
A
T
L
I
G
F
A
V
G
K
E
K
F
H
E
H
S
Q
E
L
I
S
I
L
V
A
L
Q
N
SD
A
L
R
S
Y
L
E
Q
S
W
S
R
I
C
R
I
L
GDDFVPLLPIVI
P
P
L
L
I
T
A
K
ATQDVGLIEEEEAANFQQYPD
W
D
V
V
Q
V
QG
K
H
I
A
I
H
T
S
V
L
D
D
K
V
S
A
M
E
L
L
Q
S
Y
A
T
L
L
RGQFAVY
V
K
E
V
M
E
EI
A
L
P
S
L
D
FYLH
D
G
V
R
A
A
G
A
T
L
I
P
I
L
L
S
C
L
L
A
AE
E
L
V
L
L
W
H
K
A
S
S
K
L
I
G
G
L
M
S
EPM
P
E
I
T
Q
V
Y
H
N
S
L
V
N
G
I
K
V
M
GDNCLS
E
D
Q
L
A
A
F
T
K
G
V
S
A
N
L
T
D
T
Y
E
R
M
Q
DRDEYNED
F
T
D
E
D
L
L
D
E
I
N
K
S
I
A
A
V
L
K
T
T
N
GHY
L
K
N
L
E
N
I
W
P
M
I
N
T
F
L
LE
P
I
L
V
I
F
A
L
V
V
I
G
D
L
I
Q
YEQTASMKNAF
I
P
K
V
T
E
C
L
ISPD
A
R
I
R
Q
A
A
S
Y
I
I
G
V
C
A
Q
YAPSTYADVCIPT
L
D
T
L
V
Q
I
V
DGSKLEEN
R
S
S
T
E
N
A
S
A
A
I
A
K
I
L
Y
A
Y
NSNIPD
T
Y
T
A
N
W
F
K
T
LPTITD
K
E
A
A
S
F
N
Y
Q
F
L
S
QVCAQSN
I
S
A
V
V
D
S
V
I
Q
A
L
N
E
RSLT
V
I
S
S
V
K
K
L
L
G
F
L
P
S
S
D
A
M
A
I
F
N
RYP
A
D
I
M
E
K
V
H
K
W
F
30
Fugue
63.68
15%
-23
- C4 -
3WX4
-
ARN_BPT4
A:
[1-98]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MII
D
S
Q
S
V
V
Q
Y
T
F
K
I
--
D
I
L
E
K
L
Y
--
K
F
L
P
N
L
Y
H
S
--------------
I
V
N
E
L
V
E
E
L
H
L
-----
E
N
N
D
F
L
I
-
G
T
Y
K
D
L
S
K
AG
Y
F
Y
V
I
P
A
P
G
----
K
N
I
--
D
----
D
V
L
----
K
T
I
M
---
I
Y
V
H
D
Y
E
I
E
D
Y
F
E
L
E
H
H
H
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
63.60
28%
23
- C3 -
1T2A
1
GMDS_HUMAN
A:
[280-348]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
S
V
R
--
E
F
V
E
K
S
F
L
H
--------------
I
G
K
T
I
V
W
E
-
G
K
-----
N
E
N
E
V
G
R
-
C
K
E
T
G
K
V
H
-------
V
T
V
D
LKYY
R
P
T
--
E
----
V
D
F
----
L
Q
G
D
C
T
K
A
K
Q
K
-
L
N
W
K
P
R
V
A
F
D
E
L
V
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
60.75
50%
-91
- C3 -
1Z59
-
TOP6B_SULSH
A:
[244-269]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
N
L
--
K
R
D
Y
T
I
K
--
E
F
L
V
N
E
F
Q
S
--------------
I
G
D
T
T
A
D
K
-
I
L
-----
E
L
A
G
L
K
P
-
N
K
K
V
K
N
L
T
-------
E
E
E
I
----
T
R
L
--
V
----
E
T
F
----
K
K
Y
E
---
D
F
R
S
-
P
S
A
D
S
L
S
V
I
G
E
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
60.35
50%
-91
- C3 -
2HKJ
-
TOP6B_SULSH
A:
[244-269]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
N
L
--
K
R
D
Y
T
I
K
--
E
F
L
V
N
E
F
Q
S
--------------
I
G
D
T
T
A
D
K
-
I
L
-----
E
L
A
G
L
K
P
-
N
K
K
V
K
N
L
T
-------
E
E
E
I
----
T
R
L
--
V
----
E
T
F
----
K
K
Y
E
---
D
F
R
S
-
P
S
A
D
S
L
S
V
I
G
E
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
58.82
50%
-84
- C3 -
1Z5A
-
TOP6B_SULSH
A:
[244-269]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
N
L
--
K
R
D
Y
T
I
K
--
E
F
L
V
N
E
F
Q
S
--------------
I
G
D
T
T
A
D
K
-
I
L
-----
E
L
A
G
L
K
P
-
N
K
K
V
K
N
L
T
-------
E
E
E
I
----
T
R
L
--
V
----
E
T
F
----
K
K
Y
E
---
D
F
R
S
-
P
S
A
D
S
L
S
V
I
G
E
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
58.01
50%
-79
- C3 -
1Z5B
1
TOP6B_SULSH
A:
[244-269]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
N
L
--
K
R
D
Y
T
I
K
--
E
F
L
V
N
E
F
Q
S
--------------
I
G
D
T
T
A
D
K
-
I
L
-----
E
L
A
G
L
K
P
-
N
K
K
V
K
N
L
T
-------
E
E
E
I
----
T
R
L
--
V
----
E
T
F
----
K
K
Y
E
---
D
F
R
S
-
P
S
A
D
S
L
S
V
I
G
E
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
57.72
50%
-97
- C3 -
1MX0
-
TOP6B_SULSH
A:
[247-272]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
N
L
--
K
R
D
Y
T
I
K
--
E
F
L
V
N
E
F
Q
S
--------------
I
G
D
T
T
A
D
K
-
I
L
-----
E
L
A
G
L
K
P
-
N
K
K
V
K
N
L
T
-------
E
E
E
I
----
T
R
L
--
V
----
E
T
F
----
K
K
Y
E
---
D
F
R
S
-
P
S
A
D
S
L
S
V
I
G
E
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_CBE
57.20
50%
-89
- C3 -
1MX0
1
TOP6B_SULSH
D:
[247-272]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
N
L
--
K
R
D
Y
T
I
K
--
E
F
L
V
N
E
F
Q
S
--------------
I
G
D
T
T
A
D
K
-
I
L
-----
E
L
A
G
L
K
P
-
N
K
K
V
K
N
L
T
-------
E
E
E
I
----
T
R
L
--
V
----
E
T
F
----
K
K
Y
E
---
D
F
R
S
-
P
S
A
D
S
L
S
V
I
G
E
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
56.62
50%
-94
- C3 -
1Z5C
-
TOP6B_SULSH
A:
[244-269]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
N
L
--
K
R
D
Y
T
I
K
--
E
F
L
V
N
E
F
Q
S
--------------
I
G
D
T
T
A
D
K
-
I
L
-----
E
L
A
G
L
K
P
-
N
K
K
V
K
N
L
T
-------
E
E
E
I
----
T
R
L
--
V
----
E
T
F
----
K
K
Y
E
---
D
F
R
S
-
P
S
A
D
S
L
S
V
I
G
E
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
53.58
50%
-62
- C3 -
1MU5
-
TOP6B_SULSH
A:
[246-271]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
N
L
--
K
R
D
Y
T
I
K
--
E
F
L
V
N
E
F
Q
S
--------------
I
G
D
T
T
A
D
K
-
I
L
-----
E
L
A
G
L
K
P
-
N
K
K
V
K
N
L
T
-------
E
E
E
I
----
T
R
L
--
V
----
E
T
F
----
K
K
Y
E
---
D
F
R
S
-
P
S
A
D
S
L
S
V
I
G
E
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
51.59
13%
8
- C4 -
1TDP
-
CB2I_CARML
A:
[1-111]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDIKS
Q
T
L
Y
L
N
L
S
E
A
--
Y
K
D
P
E
V
K
A
N
E
F
L
S
K
L
V
V
Q
--------------
C
A
G
K
L
T
A
S
-
N
S
-----
E
N
S
Y
I
E
V
-
I
S
L
L
S
R
G
I
-------
S
S
Y
Y
----
L
S
H
--
K
----
R
I
I
P
SSM
L
T
I
Y
---
T
Q
I
Q
-
K
D
I
K
N
G
N
I
D
T
E
K
L
R
K
Y
E
I
A
K
GLMSVPYIYF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
51.19
39%
-26
- C3 -
1MU5
-
TOP6B_SULSH
A:
[243-275]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
L
I
N
N
L
--
K
R
D
Y
T
I
K
--
E
F
L
V
N
E
F
Q
S
--------------
I
G
D
T
T
A
D
K
-
I
L
-----
E
L
A
G
L
K
P
-
N
K
K
V
K
N
L
T
-------
E
E
E
I
----
T
R
L
--
V
----
E
T
F
----
K
K
Y
E
---
D
F
R
S
-
P
S
A
D
S
L
S
V
I
G
E
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
51.14
38%
-4
- C3 -
2WIV
-
?
A:
[189-222]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
A
--
E
M
L
E
D
K
R
V
N
--------------
P
G
D
G
L
A
D
S
-
L
L
-----
D
A
A
R
A
G
E
-
I
T
E
S
E
A
I
A
-------
T
I
L
V
----
F
Y
A
--
V
----
G
H
M
----
A
I
G
Y
---
L
I
A
S
-
G
I
E
L
F
A
R
R
P
E
V
F
T
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
50.93
38%
3
- C3 -
2WIY
-
?
A:
[189-222]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
A
--
E
M
L
E
D
K
R
V
N
--------------
P
G
D
G
L
A
D
S
-
L
L
-----
D
A
A
R
A
G
E
-
I
T
E
S
E
A
I
A
-------
T
I
L
V
----
F
Y
A
--
V
----
G
H
M
----
A
I
G
Y
---
L
I
A
S
-
G
I
E
L
F
A
R
R
P
E
V
F
T
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
47.40
20%
31
- C4 -
3CJM
8
?
A:
[28-282]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S
A
N
T
V
F
F
D
K
I
N
D
L
L
V
A
S
V
K
E
FE
G
T
V
G
I
S
Y
L
DLETG
E
Q
R
S
V
NGQHEFYTASTI
K
V
P
L
T
M
L
V
A
D
T
V
A
S
GQKKWT
D
L
I
P
Y
N
AEEDYEEG
T
G
I
I
A
Y
N
I
--
Q
P
E
Y
P
L
K
--
T
L
Q
E
Y
A
I
T
Y
---------------
S
D
N
I
A
K
N
M
L
Y
D
T
L
GG
D
A
K
A
K
R
E
M
Y
Q
R
Y
L
H
K
T
-------
P
S
I
E
----
E
P
Q
F
S
S
----
E
D
A
----
L
V
I
L
---
Q
K
L
Y
-
T
E
K
A
T
----
K
P
D
Y
Q
A
I
Y
D
S
M
K
Q
SVFHERMETPTTQGK
V
A
H
K
I
G
S
Y
DE
F
I
H
D
M
G
I
L
ETPH
P
F
A
L
A
I
F
T
K
G
PD
N
A
K
S
A
A
F
I
A
S
V
T
D
K
L
W
Q
L
Q
V
S
E
Y
P
N
Q----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
46.73
38%
2
- C3 -
4EP6
-
?
A:
[187-220]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
A
--
E
M
L
E
D
K
R
V
N
--------------
P
G
D
G
L
A
D
S
-
L
L
-----
D
A
A
R
A
G
E
-
I
T
E
S
E
A
I
A
-------
T
I
L
V
----
F
Y
A
--
V
----
G
H
M
----
A
I
G
Y
---
L
I
A
S
-
G
I
E
L
F
A
R
R
P
E
V
F
T
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
46.23
24%
22
- C4 -
4UI9
-
APC4_HUMAN
I:
[6-757]
TCFPSFRVVGEKQLPQEIIFLVWSPKRDLIALANTAGEVLLHRLASFHRVWSFPPNENTGKEVTCLAWRPDGKLLAFALADTKKIVLCDVEKPESLHSFSVEAPVSCMHWMEVTVESSVLTSFYEDESNLLLPKLPTLPKNYSNTSKIFSEENSDEIIKLLGDVRLNILVLGGSSGFIELYAYGMFKIARVTGIAGTCLALCLSSDLKSLSVVTEVSTNGASEVSYFQLETNLLYSFLPEVTRMARKFTHISALLQYINLSLTCMCEAWEEILMQMDSRLTKFVQEKNTTTSVQDEFMHLLLWGKASAELQTLLMNQLTVKGLKKLGQSIESSYSSIQKLVISHLQSGSESLLYHLSELKGMASWKQKYEPLGLDAAGIEEAITAVGSFILKANELLQVIDSSMKNFKAFFRWLYVA
M
L
R
M
T
D
K
M
TQ
K
D
I
T
F
V
A
--
E
F
L
T
E
H
F
N
F
--------------
N
V
E
R
V
G
Q
Y
-
L
K
-----
D
E
D
D
-------
D
L
V
S
P
-------
P
N
T
E
----
G
N
Q
--
W
----
Y
D
F
----
L
Q
N
S
---
S
H
L
K
-
E
-
S
P
L
L
F
P
Y
Y
P
R
K
S
LHFVKRRMENIIDQCLQKPADVIGKSMNQAICIPLYRDTRSEDSTRRLFKFPFLWNNKTSNLHYLLFTILEDSLYKMCILRRHTDISQSVSNGLIAIKFGSFTYATTEKVRRSIYSCLDAQFYDDETVTVVLKDTVGREGRDRLLVQLPLSLVYNSEDSAEYQFTGTYSTRLDEQCSAIPTRTMHFEKHWRLLESMKAQYVAGNGFRKVSCVLSSNLRHVRVFEMDIDDEWELDES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
45.87
36%
-26
* C4 *
1XKM
2
?
B:
[1-25]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
V
S
G
L
--
I
E
A
R
K
Y
L
--
E
Q
L
H
R
K
L
K
N
--------------
C
K
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
43.15
39%
-76
- C3 -
2ZBK
-
TOP6B_SULSH
B:
[242-274]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
L
I
N
N
L
--
K
R
D
Y
T
I
K
--
E
F
L
V
N
E
F
Q
S
--------------
I
G
D
T
T
A
D
K
-
I
L
-----
E
L
A
G
L
K
P
-
N
K
K
V
K
N
L
T
-------
E
E
E
I
----
T
R
L
--
V
----
E
T
F
----
K
K
D
E
---
D
F
R
S
-
P
S
A
D
S
L
S
V
I
G
E
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------