@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0192: (2016-03-13 )
MIELKNVYRTFKNGDKNIRVLKDINIHINAGEFIAIMGPSGSGKSTLINILGFIDREYHGEYLFEGSNYQTQSDNQLANIRNKTVGFVFQNFKLIHNNTILENISMPLVYTNMNTIERKNKVMTVLSAVGLDGKGDFTPSKLSGGQQQRVAIARAIINNPKFIIADEPTGALDSDTSKIIMDIFTSLNRDNHTTIILVTHDRKVAEKADRIIHILDGRIQHEEVIK
Atome Classification :
(40 SA)
-.........10.-.......20........30........40........50........60........70........80........90-........100.......110--.-.---...---...120.......130..-.....--------------140.......150.......160.......170.......180.......190.......200...-..-..210.......----220....-----------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MI
E
L
K
N
V
Y
R
T
F
K-NGDK
N
I
R
V
L
K
D
I
N
I
H
INA
G
E
F
I
A
I
MGPSGS
G
K
S
T
L
I
N
I
L
G
F
ID
R
E
YH
G
E
Y
L
FEGSNYQTQSDN
Q
L
A
N
I
RNK
T
V
G
F
V
F
Q
N
-
F
K
L
IHNNT
I
L
ENISM
P
L
V
YT---N-M---
N
T
I
---
E
R
K
N
K
V
M
T
V
L
S
A
VGLDGK-GDF
T
P
--------------
S
KLSGG
Q
Q
Q
R
V
A
I
A
R
A
I
INNP
K
F
I
I
ADEPTGALDS
D
T
S
K
I
I
M
D
I
F
T
S
LNRDN
H
T
T
I
I
L
V
THD
R
K
V
A
-
E
K
-
A
D
R
I
I
H
ILDGRI----
Q
H
E
E
VIK-----------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
99.35
45%
-115
- C1 -
1L2T
4
Y796_METJA
B:
[1-230]
-
M
I
K
L
K
N
V
T
K
T
Y
K
-
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
I
F
K
YRG
A
-
M
---
S
G
E
---
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
--------------
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
----
E
R
E
E
K
L
R
-----------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
97.38
45%
-111
- C1 -
1L2T
4
Y796_METJA
A:
[1-230]
-
M
I
K
L
K
N
V
T
K
T
Y
K
-
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
I
F
K
YR
G
A
-
M
---
S
G
E
---
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
--------------
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
----
E
R
E
E
K
L
R
-----------------------------------------------------------------------------------------------------------------
117
HHSearch
94.86
45%
-108
- C1 -
3TIF
7
Y796_METJA
A:
[1-229]
-
M
V
K
L
K
N
V
T
K
T
Y
K
-
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
I
F
K
---
Y
-
R
G
A
M
S
G
E
---
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
--------------
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
----
E
R
E
E
K
L
------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
94.33
44%
-114
- C1 -
3TIF
7
Y796_METJA
B:
[1-230]
-
M
V
K
L
K
N
V
T
K
T
Y
K
-
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
I
F
K
YRG
A
-
M
---
S
G
E
---
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
--------------
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
----
E
R
E
E
K
L
R
-----------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
94.25
44%
-108
- C1 -
3TIF
7
Y796_METJA
A:
[1-230]
-
M
V
K
L
K
N
V
T
K
T
Y
K
-
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
I
F
K
YR
G
A
-
M
---
S
G
E
---
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
--------------
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
----
E
R
E
E
K
L
R
-----------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
93.60
44%
-106
- C1 -
1F3O
2
Y796_METJA
A:
[2-230]
--
I
K
L
K
N
V
T
K
T
Y
K
-
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
I
F
K
---
Y
-
R
---
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
--------------
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
E
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
----
E
R
E
E
K
L
R
-----------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
87.73
37%
-113
- C1 -
3TUZ
1
METN_ECOLI
C:
[24-248]
-
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
---
N
-
T
---
P
K
D
---
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
--------------
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
----
I
E
Q
D
T
V
------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
87.33
37%
-104
- C1 -
3TUI
1
METN_ECOLI
H:
[24-248]
-
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
---
N
-
T
---
P
K
D
---
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
--------------
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
----
I
E
Q
D
T
V
------------------------------------------------------------------------------------------------------------------
115
HHSearch
85.67
41%
-110
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[4-222]
-
I
L
R
A
E
N
I
K
K
V
I
R
-
G
----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
E
L
S
L
L
R
N
R
K
L
G
F
V
F
Q
F
-
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
V
P
M
L
K
M
---
G
-
K
---
P
K
K
---
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
K
-
L
S
R
K
P
--------------
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
E
G
-
G
T
S
I
V
M
V
T
H
E
R
E
L
A
-
E
L
-
T
H
R
T
L
E
M
K
D
G
K
V
----
V
G
E
I
T
-------------------------------------------------------------------------------------------------------------------
122
Fugue
84.79
37%
-110
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
H
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
---
N
-
T
---
P
K
D
---
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
--------------
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
----
I
E
Q
D
T
V
S
EVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV
24
PsiBlast_CBE
84.48
37%
-111
- C1 -
3TUZ
1
METN_ECOLI
H:
[24-248]
-
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
---
N
-
T
---
P
K
D
---
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
--------------
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
----
I
E
Q
D
T
V
------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
84.04
37%
-104
- C1 -
3TUZ
1
METN_ECOLI
G:
[24-248]
-
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
---
N
-
T
---
P
K
D
---
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
--------------
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
----
I
E
Q
D
T
V
------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
83.90
37%
-107
- C1 -
3TUI
1
METN_ECOLI
C:
[24-248]
-
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
---
N
-
T
---
P
K
D
---
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
--------------
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
----
I
E
Q
D
T
V
------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
82.63
37%
-105
- C1 -
3TUI
1
METN_ECOLI
G:
[24-248]
-
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
---
N
-
T
---
P
K
D
---
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
--------------
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
----
I
E
Q
D
T
V
------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
82.38
37%
-106
- C1 -
3TUI
1
METN_ECOLI
D:
[24-248]
-
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
---
N
-
T
---
P
K
D
---
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
--------------
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
----
I
E
Q
D
T
V
------------------------------------------------------------------------------------------------------------------
101
HHSearch
81.99
38%
-104
- C1 -
3TUI
1
METN_ECOLI
C:
[24-248]
-
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
---
N
-
T
---
P
K
D
---
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
--------------
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
-
C
D
C
V
A
V
I
S
N
G
E
L
----
I
E
Q
D
T
V
------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
81.52
37%
-105
- C1 -
3TUZ
1
METN_ECOLI
D:
[24-248]
-
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
R
-
R
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
E
L
D
---
N
-
T
---
P
K
D
---
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
--------------
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
----
I
E
Q
D
T
V
------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
79.67
42%
-107
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[15-220]
-----------------
R
G
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
E
L
S
L
L
R
N
R
K
L
G
F
V
F
Q
F
-
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
V
P
M
L
K
M
---
G
-
K
---
P
K
K
---
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
K
-
L
S
R
K
P
--------------
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
-
E
G
G
T
S
I
V
M
V
T
H
E
R
E
L
A
-
E
L
-
T
H
R
T
L
E
M
K
D
G
K
V
----
V
G
E
---------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
79.63
42%
-108
- C1 -
2PCJ
1
LOLD_AQUAE
B:
[15-220]
-----------------
R
G
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
E
L
S
L
L
R
N
R
K
L
G
F
V
F
Q
F
-
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
V
P
M
L
K
M
---
G
-
K
---
P
K
K
---
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
K
-
L
S
R
K
P
--------------
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
-
E
G
G
T
S
I
V
M
V
T
H
E
R
E
L
A
-
E
L
-
T
H
R
T
L
E
M
K
D
G
K
V
----
V
G
E
---------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
79.16
42%
-106
- C1 -
2PCL
12
LOLD_AQUAE
A:
[15-220]
-----------------
R
G
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
E
L
S
L
L
R
N
R
K
L
G
F
V
F
Q
F
-
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
V
P
M
L
K
M
---
G
-
K
---
P
K
K
---
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
K
-
L
S
R
K
P
--------------
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
-
E
G
G
T
S
I
V
M
V
T
H
E
R
E
L
A
-
E
L
-
T
H
R
T
L
E
M
K
D
G
K
V
----
V
G
E
---------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
78.10
35%
-116
- C1 -
4HLU
3
ECFA1_THEMA
C:
[12-217]
--
I
E
L
N
S
V
--
S
F
R
Y
N
G
D
---
Y
V
L
K
D
V
N
A
E
F
E
T
G
K
I
Y
V
V
V
G
K
N
G
S
G
K
T
T
L
L
K
I
L
A
G
L
-
L
A
A
A
G
E
I
F
L
D
G
S
----
P
A
D
P
F
L
L
R
---
K
N
V
G
Y
V
F
Q
N
P
S
S
Q
I
I
G
A
T
V
E
E
D
V
A
F
S
L
E
I
M
---
G
-
L
---
D
E
S
---
E
M
R
K
R
I
K
K
V
L
E
L
V
G
L
S
G
L
-
A
A
A
D
P
--------------
L
N
L
S
G
G
Q
K
Q
R
L
A
I
A
S
M
L
A
R
D
T
R
F
L
A
L
D
E
P
V
S
M
L
D
P
P
S
Q
R
E
I
F
Q
V
L
E
S
L
-
K
N
E
G
K
G
I
I
L
V
T
H
E
L
E
Y
L
-
D
D
-
M
D
F
I
L
H
I
S
N
G
T
I
----------------------------------------------------------------------------------------------------------------------------
119
HHSearch
73.14
38%
-115
* C1 *
2OLJ
4
?
A:
[24-243]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
K
D
T
N
-
L
N
K
V
R
-
E
E
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
---
R
K
W
---
P
R
E
---
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
P
--------------
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
----
I
E
E
G
K
P
------------------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
69.36
34%
-102
- C1 -
2FGK
2
HLYBP_ECOLX
C:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
ELREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
97
PsiBlast_CBE
69.09
34%
-103
- C1 -
1XEF
3
D:
[18-225]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
ELREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
100
PsiBlast_CBE
68.73
34%
-106
- C1 -
1XEF
3
HLYBP_ECOLX
A:
[18-225]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
E
LREGYN
T
I
V
G
EQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
92
PsiBlast_CBE
68.45
34%
-107
- C1 -
2FGJ
2
D:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
ELREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
99
PsiBlast_CBE
68.35
34%
-105
- C1 -
1XEF
3
HLYBP_ECOLX
B:
[18-225]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
ELREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
95
PsiBlast_CBE
68.34
34%
-104
- C1 -
2FGJ
2
HLYBP_ECOLX
A:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
E
LREGYNTIVGEQ
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
98
PsiBlast_CBE
68.05
34%
-113
- C1 -
1XEF
3
HLYBP_ECOLX
C:
[18-225]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
ELREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
66.88
34%
-100
- C1 -
2FGK
2
HLYBP_ECOLX
A:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
E
LREGYN
T
I
V
G
EQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
78
PsiBlast_CBE
66.44
34%
-102
- C1 -
2FGK
2
HLYBP_ECOLX
B:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
ELREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
66.44
34%
-99
- C1 -
2PMK
1
A:
[20-227]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
E
LREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
80
PsiBlast_CBE
66.34
34%
-97
- C1 -
2FFB
1
A:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
E
LREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
66.28
34%
-99
- C1 -
2FF7
1
A:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
E
LREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
109
HHSearch
65.86
31%
-94
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[4-228]
-
A
L
H
I
G
H
L
S
K
S
F
Q
-
N
----
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
F
S
K
N
T
N
-
L
P
V
R
-
E
R
R
L
G
Y
L
V
Q
E
-
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
N
G
---
K
-
G
---
R
T
A
---
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
L
-
A
G
R
Y
P
--------------
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
-
A
D
R
I
A
V
M
K
Q
G
R
I
----
L
Q
T
A
S
P
------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
65.65
34%
-103
- C1 -
2FGK
2
D:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
ELREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
93
PsiBlast_CBE
64.76
34%
-102
- C1 -
2FGJ
2
HLYBP_ECOLX
C:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
ELREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
96
PsiBlast_CBE
63.13
34%
-97
- C1 -
2FFA
2
A:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
E
LREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
61
PsiBlast_CBE
62.57
34%
-98
- C1 -
3B5J
1
A:
[20-227]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
A
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
E
LREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------
94
PsiBlast_CBE
62.44
34%
-101
- C1 -
2FGJ
2
HLYBP_ECOLX
B:
[24-231]
---------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
L
A
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
-
N
R
S
I
I
D
N
I
S
--
L
A
N
P
---
G
-
M
---
S
----------
V
E
K
V
I
Y
A
A
K
L
A
G
A
-
H
D
F
I
S
ELREGYNTIVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
--
T
V
I
I
I
A
A
R
L
S
T
V
-
K
N
-
A
D
R
I
I
V
M
E
K
G
K
I
VEQG
K
H
K
E
L
L
------------------------------------------------------------------------------------------------------------------