@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1156: (2016-03-22 )
MIQISNINKSFNKRCVLKNISFDIEQGKCIALIGKNGAGKSTLIDILIGNVNANSGEIFDKDKLLQSENRSIMFQKTMFPDQLKVIEIINLYQSFYENPLPLEEIIELTKFDSSQLNQFVNKLSGGQQRLLDFVLSLIGQPQLILLDEPTSTMDIEIREYFWSIIENLKEDNRTILYTSHYIEEVERMSDKIILIENGEIILNDSTSHIRTNQQSQITLSDEYIRKLKLDKDDLVIQKNHNGTIKIITSNVNDTILYLQQLHINLDDIEIQKVSIVDSYFNNKKQRGSNYDTKLLENRI
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10--.--.-----......20........30........40...-------.....50.......-.60....-----.--------------------.-----..70---------..--....-...80..------.---...--------------...90....-...------.-----100---.-..-------......110..------.....120---------------.......130.......140.......150.......160......-.-170..-......180.......190.......200.......210.......220-.........230....------...240.....-----------------..250.......260.......270--........280.......290.......-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
Q
ISNIN
K
S
F
--
N
--
K
-----
R
C
V
LKNI
S
F
D
IEQG
K
C
I
A
L
I
GKNGAGK
S
T
L
I
-------
D
I
L
I
GNVNANSGEI-F
D
K
D
K
L
L
-----Q--------------------S-----EN
R
----------
S
I
--
M
F
Q
K-TMFP-
D
Q
------
L
---
K
V
I
--------------
E
I
I
N
L
Y
Q
S
F
-YEN------P-----L-----
P
-
L
E
-------
E
I
I
E
L
TKF
D
S
S
------
Q
L
N
Q
F
V
N
K
---------------LSG
G
Q
Q
R
L
L
D
F
V
L
S
LIGQP
Q
L
I
L
L
DEPTS
T
M
D
I
E
I
R
E
Y
F
W
S
I
I
E
N
L-K-E-DN
R
-
T
I
L
Y
T
S
H
Y
I
E
E
V
E
RMSD
K
I
I
L
I
EN
G
E
I
I
LNDSTSHIRTNQQ
S
Q
I
T
L
S
---
D
E
Y
I
R
K
LKLDKD
D
L
V
I
------QKNHN
G
T
I
K
I
I
-----------------TSNVN
D
T
I
L
Y
L
Q
Q
LHINLD
D
I
E
I
Q
---
K
V
S
I
V
D
S
Y
FNNKKQRGSNY
D
T
K
L
LENRI-----
26
Fugue
86.61
24%
-94
- C1 -
3B60
2
MSBA_SALTY
A:
[10-581]
W
Q
T
F
R
R
L
W
P
T
I
A
PFK
A
G
L
I
V
A
G
I
A
L
I
L
N
A
A
S
D
T
F
M
L
S
L
LKPLLDDGFGKTDRSVLLW
M
P
L
V
V
I
G
L
M
I
L
R
G
I
T
S
Y
I
S
S
Y
C
I
S
W
V
S
G
K
V
V
M
T
M
R
R
R
L
F
G
H
M
M
G
MPVAFFDKQS
T
G
T
L
L
S
R
I
T
Y
D
S
E
Q
V
A
S
S
S
S
G
A
L
I
T
V
V
R
E
G
A
S
I
I
G
L
F
I
M
M
FYYS
W
Q
L
S
I
I
L
V
V
L
A
P
I
V
S
I
A
I
R
V
V
S
K
R
F
R
S
I
S
K
N
M
Q
N
T
M
G
Q
V
T
T
S
A
E
Q
M
L
K
G
H
KEVLIFGG
Q
E
V
E
T
K
R
F
D
K
V
S
N
K
M
R
L
Q
G
M
K
M
V
S
A
S
S
I
S
D
P
I
I
Q
L
I
A
S
L
A
L
A
F
V
L
Y
A
A
S
FPSVMDSLT
A
G
T
I
T
V
V
F
S
S
M
I
A
L
M
R
P
L
K
S
L
T
N
V
N
A
Q
F
Q
R
G
M
A
A
C
Q
T
L
F
A
I
L
D
SEQEK
D
E
G
K
RVIDRATG
D
L
E
F
R
N
V
T
F
T
Y
PG
R
--
E
-----
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
-------
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
-
L
M
D
G
H
D
L
-----
R
--------------------
E
Y----
T
L
A
----------
S
L
--
R
N
Q
V
-
A
L
V
S
-
Q
N
------
V
---
H
L
F
ND------------
T
V
A
N
N
I
A
Y
A
-
R
T
E
------
E
-----
Y
-----
S
-
R
E
-------
Q
I
E
E
A
A
R
--
M
A
------
Y
A
M
D
F
I
N
K
M
DNGLD
T
I
I
G
ENGVL
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
-
Q
-
K
--
N
R
-
T
S
L
V
I
A
H
R
L
S
T
I
E
Q
-
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
A
Q
-------
H
---
G
V
Y
A
Q
L
H
K
M
Q
F
G
--------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
86.19
28%
-87
- C1 -
1VPL
2
?
A:
[16-240]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
V
K
D
L
R
K
R
I
--
G
--
K
-----
K
E
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
-------
R
I
I
S
T
L
I
K
P
S
S
G
I
V
-
T
V
F
G
K
N
V
-----
V
--------------------
E
-----
E
P
H
----------
E
V
--
R
K
L
I
-
S
Y
L
P
-
E
E
AGAYRN
M
---
Q
G
I
--------------
E
Y
L
R
F
V
A
G
F
-
Y
A
S
------
S
-----
S
-----
S
E
I
E
-------
E
M
V
E
R
A
T
E
I
A
G
LGE---
K
I
K
D
R
V
S
T
---------------
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
K
Q
A
-
S
-
Q
-
E
G
L
-
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
T
G
T
V
E
E
L
K
E
R
Y
K
A
Q
---------------------------------------------------------------------------------------------------------------------
34
HHSearch
85.81
30%
-98
- C1 -
2IT1
-
?
A:
[3-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
K
L
E
N
I
V
K
K
F
--
G
--
N
-----
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
-------
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
-
Y
F
D
E
K
D
V
-----
T
ELPPK---------------
D
-----
R
N
V
----------
G
L
--
V
F
Q
N
-
W
A
L
Y
-
P
H
------
M
---
T
V
Y
--------------
K
N
I
A
F
P
L
E
L
-
R
K
A
------
P
R
E
E
I
D
K
-----
K
-
V
R
-------
E
V
A
K
M
L
H
I
D
K
L
-------
L
N
R
Y
P
W
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
-
Q
K
E
-
L
G
I
-
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
------------------------------------------------------------------------------------------------------------------------
21
Fugue
84.21
23%
-73
- C1 -
1OXS
23
?
C:
[1-352]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MV
R
I
I
V
K
N
V
S
K
V
F
--
K
KG
K
-----
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
-------
R
I
I
A
G
L
D
V
P
S
T
G
E
L
-
Y
F
D
D
R
L
V
-----
A
--------------------
S
-----
N
G
K
LIVPPEDRKI
G
M
--
V
F
Q
T
-
W
A
L
Y
-
P
N
------
L
---
T
A
F
--------------
E
--
N
I
A
F
P
L
-
T
N
M
------
K
-----
M
-----
S
-
K
E
-------
E
I
R
K
R
V
E
E
V
A
K
ILDIHH
V
L
N
H
F
P
R
E
---------------
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
-
Q
-
S
-
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
LIG
E
I
N
E
L
E
G
K
V
T
N
E
G
V
V
I
GSLRFP
V
S
V
S
S
D
R
A
I
I
G
IRPEDVKLSKDVIKDDS
W
I
L
V
G
K
G
K
V
K
V
I
G
Y
Q
G
G
L
F
R
I
T
I
T
PLD
S
E
E
E
I
F
T
Y
S
D
H
P
I
H
S
G
E
E
V
L
V
Y
V
R
K
D
K
I
KVFEK
4
PsiBlast_PDB
83.56
30%
-110
- C1 -
2IT1
-
?
A:
[4-213]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
L
E
N
I
V
K
K
F
--
G
--
N
-----
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
-------
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
-
Y
F
D
E
K
D
V
TELPP
K
--------------------
D
-----
R
N
V
----------
G
L
--
V
F
Q
N
-
W
A
L
Y
-
P
H
------
M
---
T
V
Y
--------------
K
N
I
A
F
P
L
E
L
-
R
K
A
------
P
-----
R
E
E
I
D
K
K
-
V
R
-------
E
V
A
K
M
L
H
I
D
-
K
------
L
L
N
R
Y
P
W
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
-
E
-
L
G
I
-
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
81.78
25%
-103
- C1 -
3RLF
3
MALK_ECOLI
A:
[3-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
Q
L
Q
N
V
T
K
A
W
--
G
--
E
-----
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
-------
R
M
I
A
G
L
E
T
I
T
S
G
D
L
-
F
I
G
E
K
R
M
-----
N
--------------------
D
TPPAE
R
G
V
----------
G
M
--
V
F
Q
S
-
Y
A
L
Y
-
P
H
------
L
---
S
V
A
--------------
E
N
M
S
F
G
L
K
L
-
A
G
A
------
K
K
E
V
I
N
Q
-----
R
-
V
N
-------
Q
V
A
E
V
L
Q
L
A
H
L
-------
L
D
R
K
P
K
A
---------------
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
-
H
K
R
-
L
G
R
-
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
-----------------------------------------------------------------------------------------------------------------------
36
HHSearch
80.86
27%
-97
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[4-236]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
H
I
G
H
L
S
K
S
F
--
Q
--
N
-----
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
-------
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
-
S
L
S
G
K
T
I
-----
F
SKN
T
N
L
P
VR-----------
E
-----
R
R
L
----------
G
Y
--
L
V
Q
E
-
G
V
L
F
-
P
H
------
L
---
T
V
Y
--------------
R
N
I
A
Y
G
L
G
N
-
G
K
G
RT
A
Q
E
-
R
-----
Q
-----
R
-
I
E
-------
A
M
L
E
L
T
G
I
S
E
L
-------
A
G
R
Y
P
H
E
---------------
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
-
L
R
A
-
N
G
K
-
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
-----------------------------------------------------------------------------------------------------------------------
39
HHSearch
80.57
26%
-98
- C1 -
1OXX
21
?
K:
[3-233]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
I
V
K
N
V
S
K
V
F
--
K
--
K
GK---
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
-------
R
I
I
A
G
L
D
V
P
S
T
G
E
L
-
Y
F
D
D
R
L
V
-----
A
SNGKLIVPPE----------
D
-----
R
K
I
----------
G
M
--
V
F
Q
T
-
W
A
L
Y
-
P
N
------
L
---
T
A
F
--------------
E
N
I
A
F
P
L
T
N
-
M
K
M
SKEEI-
R
-----
K
-----
R
-
V
E
-------
E
V
A
K
I
L
D
I
H
H
V
-------
L
N
H
F
P
R
E
---------------
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
-
Q
S
R
-
L
G
V
-
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
-----------------------------------------------------------------------------------------------------------------------
40
HHSearch
78.94
26%
-108
- C1 -
3TUI
1
METN_ECOLI
C:
[24-256]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
--
H
--
Q
GTRT-
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
-------
R
C
V
N
L
L
E
R
P
T
E
G
S
V
-
L
V
D
G
Q
E
L
-----
T
TLSESELTKA----------
R
-----
R
Q
I
----------
G
M
--
I
F
Q
H
-
F
N
L
L
-
S
S
------
R
---
T
V
F
--------------
G
N
V
A
L
P
L
E
L
-
D
N
T
------
P
KDEVK
R
-----
R
-
V
T
-------
E
L
L
S
L
V
G
L
G
D
K
-------
H
D
S
Y
P
S
N
---------------
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
-
L
G
L
-
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
-----------------------------------------------------------------------------------------------------------------------
38
HHSearch
78.28
27%
-103
- C1 -
2YYZ
3
?
A:
[3-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
R
V
V
N
L
K
K
Y
F
--
G
--
K
-----
V
K
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
-------
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
-
Y
F
D
D
V
L
V
-----
N
DIPPK---------------
Y
-----
R
E
V
----------
G
M
--
V
F
Q
N
-
Y
A
L
Y
-
P
H
------
M
---
T
V
F
--------------
E
N
I
A
F
P
L
R
A
-
R
R
I
------
S
KD
E
V
E
K
-----
R
-
V
V
-------
E
I
A
R
K
L
L
I
D
N
L
-------
L
D
R
K
P
T
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
-
Q
Q
E
-
L
G
I
-
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
S
P
------------------------------------------------------------------------------------------------------------------------
47
HHSearch
77.80
25%
-106
- C1 -
2OLJ
4
?
A:
[24-250]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
D
V
H
Q
L
K
K
S
F
--
G
--
S
-----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
-------
R
C
L
N
L
L
E
D
F
D
E
G
E
I
-
I
I
D
G
I
N
L
-----
K
AKDTN
L
N
K
V
-----------
R
-----
E
E
V
----------
G
M
--
V
F
Q
R
-
F
N
L
F
-
P
H
------
M
---
T
V
L
--------------
N
N
I
T
L
A
P
M
K
-
V
R
K
WP
R
E
K
A
E
-----
A
-----
K
-
A
M
-------
E
L
L
D
K
V
G
L
K
D
K
-------
A
H
A
Y
P
D
S
---------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
76.14
27%
-107
- C1 -
2YZ2
-
ECFA2_THEMA
A:
[3-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
V
V
N
V
S
H
I
F
--
H
--
R
GTPLE
K
K
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
-------
Q
I
V
A
G
L
I
E
P
T
S
G
D
V
L
Y
D
G
E
R
K
K
-----
G
--------------------
Y
-----
E
I
R
RN
I
-------
G
I
--
A
F
Q
----
Y
P
E
D
Q
------
F
FAE
R
V
F
D
-------------
E
V
A
F
A
V
K
N
F
-
Y
P
D
------
R
-----
D
-----
P
-
V
P
-------
L
V
K
K
A
M
E
F
V
G
L
------
D
F
D
S
F
K
D
R
VPFF-----------
L
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
R
I
V
E
K
W
-
K
-
T
-
L
G
K
-
T
V
I
L
I
S
H
D
I
E
T
V
I
N
H
V
D
R
V
V
V
L
E
K
G
K
K
V
F
D
G
T
--------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
75.84
27%
-103
- C1 -
4U00
3
?
A:
[4-236]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
R
I
R
N
L
H
K
W
F
--
G
--
P
-----
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
RLE
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
-
K
D
-
D
R
A
L
-----
R
--------------------
E
-----
I
R
R
----------
E
V
G
M
V
F
Q
Q
F
N
L
F
P
--
H
------
M
---
T
V
L
--------------
E
N
V
T
L
A
P
M
R
-
V
R
R
------------
W
-----
P
-
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
D
------
Q
A
R
K
Y
P
A
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
-
Q
-
G
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
-----------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
75.52
27%
-107
- C1 -
4ZIR
5
ECFA2_THEMA
A:
[4-222]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
V
V
N
V
S
H
I
F
--
H
--
R
GTPLE
K
K
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
-------
Q
I
V
A
G
L
I
E
P
T
S
G
D
V
L
Y
D
G
E
--
K
-----
G
--------------------
Y
-----
E
I
R
RN
I
-------
G
I
--
A
F
Q
----
Y
P
E
D
Q
------
F
FAE
R
V
F
D
-------------
E
V
A
F
A
V
K
N
F
-
Y
P
D
------
R
-----
D
-----
P
-
V
P
-------
L
V
K
K
A
M
E
F
V
G
L
------
D
F
D
S
F
K
D
R
VPFF-----------
L
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
R
I
V
E
K
W
-
K
-
T
-
L
G
K
-
T
V
I
L
I
S
H
D
I
E
T
V
I
N
H
V
D
R
V
V
V
L
E
K
G
K
K
V
F
D
G
T
--------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
75.43
27%
-107
- C1 -
4U02
1
?
A:
[4-236]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
R
I
R
N
L
H
K
W
F
--
G
--
P
-----
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
RLE
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
-
K
D
-
D
R
A
L
-----
R
--------------------
E
-----
I
R
R
----------
E
V
G
M
V
F
Q
Q
F
N
L
F
P
--
H
------
M
---
T
V
L
--------------
E
N
V
T
L
A
P
M
R
-
V
R
R
------------
W
-----
P
-
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
D
------
Q
A
R
K
Y
P
A
Q
---------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
-
Q
-
G
G
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
-----------------------------------------------------------------------------------------------------------------
51
HHSearch
74.86
23%
-112
* C1 *
2PCJ
-
LOLD_AQUAE
A:
[4-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
R
A
E
N
I
K
K
V
I
--
R
--
G
-----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
-------
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
-
F
L
E
G
K
E
V
-----
D
YTN
E
K
E
L
S
L
L
R
---------
N
-----
R
K
L
----------
G
F
--
V
F
Q
F
-
H
Y
L
I
-
P
E
------
L
---
T
A
L
--------------
E
N
V
I
V
P
M
L
K
-
M
G
K
------
P
K
K
E
A
K
E
-----
R
-
G
E
-------
Y
L
L
S
E
L
G
L
G
D
K
-------
L
S
R
K
P
Y
E
---------------
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
-
N
-
E
-
G
G
T
-
S
I
V
M
V
T
H
E
R
E
L
A
-
E
L
T
H
R
T
L
E
M
K
D
G
K
V
V
G
E
I
T
R
-------------------------------------------------------------------------------------------------------------------------------
50
HHSearch
74.04
22%
-106
- C1 -
1B0U
4
HISP_SALTY
A:
[7-244]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
H
V
I
D
L
H
K
R
Y
--
G
--
G
-----
H
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
-------
R
C
I
N
F
L
E
K
P
S
E
G
A
I
-
I
V
N
G
Q
N
I
-----
N
L
V
R
D
KDGQLKVAD
K
N
Q
L
R
L
L
R
-----
T
R
L
----------
T
M
--
V
F
Q
H
-
F
N
L
W
-
S
H
------
M
---
T
V
L
--------------
E
N
V
M
E
A
P
I
Q
V
L
G
L
S
K
H
D
A
-
R
-----
E
-----
R
-
A
L
-------
K
Y
L
A
K
V
G
I
D
E
R
------
A
Q
G
K
Y
P
V
H
---------------
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
-
A
-
E
-
E
G
K
-
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
------------------------------------------------------------------------------------------------------------------------
33
HHSearch
73.74
24%
-101
- C1 -
1V43
-
?
A:
[12-241]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
K
L
E
N
L
T
K
R
F
--
G
--
N
-----
F
T
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
-------
R
M
I
A
G
L
E
E
P
T
E
G
R
I
-
Y
F
G
D
R
D
V
-----
T
YLPPK---------------
D
-----
R
N
I
----------
S
M
--
V
F
Q
--------
H
------
M
---
T
V
Y
--------------
E
N
I
A
F
P
L
---
K
K
F
------
P
K
D
E
I
D
K
-----
R
-
V
R
-------
W
A
A
E
L
L
Q
I
E
E
L
-------
L
N
R
Y
P
A
Q
---------------
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
-
Q
-
Q
K
L
K
V
-
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
P
N
-----------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
73.71
27%
-103
- C1 -
4HLU
2
ECFA2_THEMA
A:
[5-223]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
V
V
N
V
S
H
I
F
--
H
--
R
GTPLE
K
K
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
-------
Q
I
V
A
G
L
I
E
P
T
S
G
D
V
L
Y
D
G
E
R
K
K
-----
G
--------------------
Y
-----
E
I
R
R
N
I
-------
G
I
--
A
F
Q
----
Y
P
E
D
Q
------
F
FAE
R
V
F
D
-------------
E
V
A
F
A
V
K
N
F
-
Y
P
D
------
R
-----
D
-----
P
-
V
P
-------
L
V
K
K
A
M
E
F
V
G
L
------
D
F
D
S
F
K
D
R
VPFF-----------
L
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
R
I
V
E
K
W
-
K
-
T
-
L
G
K
-
T
V
I
L
I
S
H
D
I
E
T
V
I
N
H
V
D
R
V
V
V
L
E
K
G
K
K
V
F
D
G
T
--------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
73.22
26%
-115
- C1 -
3PUY
3
MALK_ECOLI
A:
[4-212]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
L
Q
N
V
T
K
A
W
--
G
--
E
-----
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
-------
R
M
I
A
G
L
E
T
I
T
S
G
D
L
-
F
I
G
E
K
R
M
NDTPP
A
--------------------
E
-----
R
G
V
----------
G
M
--
V
F
Q
S
-
Y
A
L
Y
-
P
H
------
L
---
S
V
A
E
N
M
S
F
G
L
K
L
A
GAK
K
E
V
I
N
--
Q
R
V
-
N
Q
---------------------
V
A
-------
E
V
L
Q
L
A
H
L
----------
L
D
R
K
P
K
A
---------------
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
-
R
-
L
G
R
-
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
-------------------------------------------------------------------------------------------------------------------------------------