@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1396: (2016-03-25 )
MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDHFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERDSQKGIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
Atome Classification :
(20 SA)
.........10........20........30........40........50.-........60...-.-...-.--70-......------...80........90........100......-.-110--.--......120.....-..130-.......----.140..-.....150.......160.......170.......180-.......190.......200.......210.......220...--......230.......240.......250.......260.......270.......280.......290.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTEHK
S
G
F
V
S
I
IGRPNV
G
K
S
T
F
V
N
R
V
IG
H
K
I
A
I
MSD
K
A
Q
T
T
R
N
K
I
Q
G
V
M
T-R-DD
A
Q
I
I
F
I
DTPGI-H-
K
P
K
-
H
--
K
--
L
G
D
Y
M
M
------
K
V
A
K
N
T
L
S
E
I
D
A
I
M
F
M
VNANEEIGR
G
D
E
Y
I
I
E
-
M
-
L
K
N--V--KT
P
V
F
L
V
L
N
KIDLV-
H
P
D
-
E
-
L
M
P
K
I
E
E
----
Y
Q
S
Y
M
D
-
F
T
EIVPI
S
A
LEGL
N
V
D
H
F
I
D
V
L
K
T
YLPEGPKYYPDDQI-SDH
P
E
Q
F
V
V
G
E
I
I
R
E
K
I
L
H
L
T
S
E
EIPHAIGV
N
V
D
R
M
V
K--ESE--
D
R
V
H
I
E
A
T
I
Y
V
ERDSQK
G
I
V
IGKG
G
K
K
L
K
E
V
G
K
R
A
R
R
D
I
E
M
L
LG
S
K
V
Y
L
E
L
W
V
K
V
Q
R
D
W
R
N
K
V
N
F
I
R
QIGYVEDQD
3
PsiBlast_PDB
95.29
44%
-116
- C1 -
3IEV
4
ERA_AQUAE
A:
[9-306]
----
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
-
Y
-
E
P
K
-
K
--
S
D
V
L
G
H
S
M
V
------
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
-
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
-
G
P
A
-
K
N
V
L
P
L
I
D
E
I
---
H
K
K
H
P
E
-
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
GD
A
N
P
--
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
-----
57
HHSearch
94.54
46%
-112
- C1 -
3IEV
4
ERA_AQUAE
A:
[7-307]
--
H
M
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
-
I
P
N
E
A
Q
I
I
F
L
D
T
P
G
I
-
Y
-
E
P
K
-
K
SD
V
--
L
G
H
S
M
V
------
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
-
N
F
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
-
G
P
A
-
K
N
V
L
P
L
I
D
E
----
I
H
K
K
H
P
E
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
--
G
D
A
NP
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
----
1
PsiBlast_PDB
94.29
44%
-119
- C1 -
3R9W
8
ERA_AQUAE
A:
[8-305]
----
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
-
Y
-
E
P
K
-
K
--
S
D
V
L
G
H
S
M
V
------
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
-
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
-
G
P
A
-
K
N
V
L
P
L
I
D
E
I
---
H
K
K
H
P
E
-
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
N
P
--
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
-----
2
PsiBlast_PDB
93.79
44%
-114
- C1 -
3R9X
4
ERA_AQUAE
A:
[8-305]
----
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
-
Y
-
E
P
K
-
K
--
S
D
V
L
G
H
S
M
V
------
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
-
I
K
P
--
L
--
N
K
P
V
I
V
V
I
N
K
I
D
K
I
-
G
P
A
-
K
N
V
L
P
L
I
D
E
I
---
H
K
K
H
P
E
-
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
GD
A
N
P
--
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
-----
6
PsiBlast_PDB
88.13
39%
-118
- C1 -
3IEU
7
ERA_ECOLI
A:
[8-296]
-----
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
-
H
M
E
E
K
-
R
--
A
--
I
N
R
L
M
N
------
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
W
T
P
-
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
-
Q
E
K
A
D
-
L
L
P
H
L
Q
F
----
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
--
N
E
R
--
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
------
21
PsiBlast_CBE
87.77
39%
-118
- C1 -
3IEU
9
ERA_ECOLI
B:
[8-296]
-----
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
-
H
M
E
E
K
-
R
--
A
--
I
N
R
L
M
N
------
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
W
T
P
-
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
-
Q
E
K
A
D
-
L
L
P
H
L
Q
F
----
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
--
N
E
R
--
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
------
8
PsiBlast_PDB
86.19
39%
-103
- C1 -
1WF3
4
ERA_THET8
A:
[7-296]
-----
S
G
F
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
-
E
-
G
R
R
Q
I
V
F
V
D
T
P
G
L
-
H
-
K
P
M
-
D
--
A
--
L
G
E
F
M
D
------
Q
E
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
V
D
L
R
H
P
P
T
P
E
D
E
L
V
A
R
-
A
-
L
K
P
--
L
VG
K
V
P
I
L
L
V
G
N
K
L
D
A
A
K
Y
P
E
-
E
-
A
M
---
K
A
----
Y
H
E
L
L
P
-
E
A
E
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
P
E
G
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
A
E
--
R
E
N
--
G
V
L
Y
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
-----
22
PsiBlast_CBE
86.14
39%
-113
- C1 -
1EGA
2
ERA_ECOLI
B:
[8-296]
-----
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
-
H
M
E
E
K
-
R
--
A
--
I
N
R
L
M
N
------
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
W
T
P
-
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
-
Q
E
K
A
D
-
L
L
P
H
L
Q
F
----
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
--
N
E
R
--
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
------
4
PsiBlast_PDB
85.77
39%
-110
- C1 -
1EGA
3
ERA_ECOLI
A:
[8-295]
-----
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
-
H
M
E
E
K
-
R
--
A
--
I
N
R
L
M
N
------
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
W
T
P
-
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
-
Q
E
K
A
D
-
L
L
P
H
L
Q
F
----
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
--
N
E
R
--
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-------
56
HHSearch
85.37
39%
-92
- C1 -
1WF3
4
ERA_THET8
A:
[3-298]
-
E
K
T
Y
S
G
F
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
-
E
-
G
R
R
Q
I
V
F
V
D
T
P
G
L
-
H
-
K
P
M
-
D
--
A
--
L
G
E
F
M
D
------
Q
E
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
V
D
L
R
H
P
P
T
P
E
D
E
L
V
A
R
-
A
-
L
K
P
LV
G
--
K
V
P
I
L
L
V
G
N
K
L
D
A
A
-
K
Y
P
-
E
---
E
A
M
K
A
----
Y
H
E
L
L
P
-
E
A
E
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
P
E
G
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
A
E
--
R
E
N
--
G
V
L
Y
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
R
S
---
55
HHSearch
84.60
39%
-107
- C1 -
1EGA
3
ERA_ECOLI
A:
[4-295]
-
D
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
-
H
-
M
E
E
K
R
--
A
--
I
N
R
L
M
N
------
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
-
W
T
P
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
-
Q
E
K
-
A
D
L
L
P
H
L
Q
F
----
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
--
N
E
R
--
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-------
45
Fugue
69.23
39%
-108
- C1 -
1EGA
3
ERA_ECOLI
A:
[4-182]
-
D
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
H
M
-
E
E
K
-
R
--
A
--
I
N
R
L
M
N
------
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
W
-
T
P
D
D
E
M
V
L
N
-
K
-
L
R
E
--
G
--
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
E
K
A
-
D
-
L
L
P
H
L
Q
F
----
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
-----------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
62.79
33%
-140
- C1 -
4KYU
5
DER_BACSU
B:
[6-163]
--------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
-----------------
I
Y
S
S
A
E
-
W
--
N
Y
D
F
N
L
I
D
T
G
G
I
-
D
-
I
G
D
-
E
--
P
--
F
L
A
Q
I
R
------
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
D
N
T
-----
E
-
M
R
A
N
I
Y
D
----
F
Y
S
-
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
--------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
61.97
33%
-128
- C1 -
4KYU
6
DER_BACSU
A:
[6-163]
--------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
----------
R
D
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
I
-
D
-
I
G
D
-
E
--
P
--
F
L
A
Q
I
R
------
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
D
N
T
-----
E
-
M
R
A
N
I
Y
D
----
F
Y
S
-
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
--------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
61.58
32%
-127
- C1 -
4DCU
1
DER_BACSU
A:
[26-206]
--------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
-----------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
-----------
P
--
F
L
A
Q
I
R
------
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
---------------
Y
D
----
F
Y
S
-
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
----
K
N
I
P
E
T
K
Y
-
N
E
E
V
I
Q
F
C
L
----------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
61.43
32%
-133
- C1 -
4DCV
-
DER_BACSU
A:
[26-206]
--------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
-----------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
-----------
P
--
F
L
A
Q
I
R
------
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
---------------
Y
D
----
F
Y
S
-
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
----
K
N
I
P
E
T
K
Y
-
N
E
E
V
I
Q
F
C
L
----------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
60.30
32%
-130
- C1 -
4DCS
1
DER_BACSU
A:
[26-206]
--------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
-----------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
-----------
P
--
F
L
A
Q
I
R
------
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
----------
M
R
A
N
I
Y
D
----
F
Y
S
-
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
----
K
N
I
P
E
T
K
Y
-
N
E
E
V
I
Q
F
C
L
----------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
60.11
28%
-157
- C1 -
3PR1
1
ENGB_THEMA
A:
[24-193]
------
G
E
V
A
F
V
G
R
S
N
V
G
K
S
S
L
L
N
A
L
F
N
-------------
R
S
-
I
N
F
Y
L
V
----
N
S
K
Y
Y
F
V
D
L
P
G
Y
--------------
K
E
R
M
L
W
K
R
L
V
E
D
Y
F
K
N
R
W
S
-
L
Q
M
V
F
L
L
V
D
G
R
I
P
P
Q
D
S
D
L
M
M
V
E
-
W
-
M
K
S
--
L
--
N
I
P
F
T
I
V
L
T
K
M
D
K
V
-
K
M
S
-
E
-
R
A
K
K
L
E
E
H
R
K
V
F
S
K
Y
G
E
-
Y
T
-
I
I
P
T
S
S
V
T
G
E
G
I
S
E
L
L
D
L
I
S
T
L
L
K
-------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
60.02
31%
-138
- C1 -
2HJG
1
DER_BACSU
A:
[6-189]
--------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
-----------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
--------------
P
--
F
L
A
Q
I
R
------
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
-
I
-
L
Y
R
--
T
--
K
K
P
V
V
L
A
V
N
K
L
D
N
-----------
N
I
Y
D
----
F
Y
S
-
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
----
K
N
I
P
E
T
K
Y
-
N
E
E
V
I
Q
F
C
L
----------------------------------------------------------------------------------------------------------------
63
HHSearch
58.48
29%
-107
- C1 -
1MKY
3
DER_THEMA
A:
[2-183]
------
A
T
V
L
I
V
G
R
P
N
V
G
K
S
T
L
F
N
K
L
V
K
--------------
D
P
V
Q
D
T
V
E
-
W
-
Y
G
K
T
F
K
L
V
D
T
C
G
V
-
F
-
D
N
P
-
Q
D-
I
--
I
S
Q
K
M
K
------
E
V
T
L
N
M
I
R
E
A
D
L
V
L
F
V
V
D
G
K
R
G
I
T
K
E
D
E
S
L
A
D
-
F
-
L
R
K
--
S
--
T
V
D
T
I
L
V
A
N
K
A
E
N
L
-
R
E
F
-
E
--
R
E
V
K
P
E
----
L
Y
-
S
L
G
-
F
G
E
P
I
P
V
S
A
E
H
N
I
N
L
D
T
M
L
E
T
I
I
K
K
L
E
E
------------------------------------------------------------------------------------------------------------------------------------