@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1701: (2016-03-28 )
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
Atome Classification :
(20 SA)
-------------------------------.........10........20........30.....--...40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180-........190.......200.......--210.......220......-.230..---......240.-......----250-.........260......----.-------------270-----------.-----.......--.280.......290..-------------.-----------....-----------------------------------------300.--------------..------------....310.......320.......330.......340.....----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------M
N
H
Y
I
R
T
I
G
S
M
L
I
L
V
Y
S
M
L
A
A
F
L
F
I
D
K
V
F
V
N
I
I
Y
FQ--
G
M
F
Y
T
Q
IFG
I
P
V
F
L
F
L
N
L
I
I
I
L
L
C
I
I
V
G
S
V
L
A
Y
K
INQQN
D
W
I
K
T
Q
I
E
R
SMEG
E
T
VGINDQ
N
I
E
I
Y
S
E
T
L
D
L
Y
H
T
LV
P
L
N
Q
E
L
H
K
L
R
L
KTQNLTNENYNI
N
D
V
K
V
K
K
I
I
E
D
E
R
Q
R
L
A
R
E
L
H
D
S
V
S
Q
Q
L
F
A
A
S
M
M
L
S
A
I
K
ETKLEPP--LDQQ
I
P
I
L
E
K
M
V
Q
D
S
Q
L
E
M
R
A
L
L
L
H
LRP--LGLKD
K
S
L
G
E
G
I
K
D
L
V
I
D
L
-
Q
KK-V
P
---
M
K
V
V
H
E
I
Q
DF-KVPK
G
I
----
E
---
D
H
L
F
R
I
T
Q
E
A
I
S
N
T
L
RHS----N-------------G-------------
T
-----
K
V
T
V
E
L
F--NKD
D
Y
L
L
L
R
I
QDNGKG-------------F-----------
N
V
D
E
-----------------------------------------
K
L
E
Q
--------------
S
Y------------G
L
K
N
M
R
E
R
A
L
EIG
A
T
F
H
I
V
SLPDSG
T
R
I
E
V
KAPLNKEDSYDD----
1
PsiBlast_PDB
95.41
100%
-85
- C2 -
4GT8
2
A:
[4-133]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
D
K
S
L
G
E
G
I
K
D
L
V
I
D
L
-
Q
K
K
-
V
P
---
M
K
V
V
H
E
I
Q
D
F
-
K
V
P
K
G
I
----
E
---
D
H
L
F
R
I
T
Q
E
A
I
S
N
T
L
R
H
S
----
N
-------------
G
-------------
T
-----
K
V
T
V
E
L
F
--
N
K
D
D
Y
L
L
L
R
I
Q
D
N
G
K
G
-------------
F
-----------
N
V
D
E
-----------------------------------------
K
L
E
Q
--------------
S
Y
------------
G
L
K
N
M
R
E
R
A
L
E
I
G
A
T
F
H
I
V
S
L
P
D
S
G
T
R
I
E
V
K
A
P
L
N
K
----------
3
PsiBlast_PDB
64.55
22%
-56
- C2 -
3EHF
2
DESK_BACSU
A:
[9-194]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
A
R
D
L
H
D
T
L
G
Q
K
L
S
L
I
G
L
K
S
D
L
A
R
K
L
I
Y
K
D
P
E
Q
A
A
R
E
L
K
S
V
Q
Q
T
A
R
T
S
L
N
E
V
R
K
I
V
S
S
M
K
G
--
I
R
L
K
D
E
L
I
N
--
I
K
Q
I
L
-----
E
A
-
A
D
---
I
M
F
I
Y
E
--
E
E
-
K
W
P
E
N
I
S
L
L
N
E
---
N
I
L
S
M
C
L
K
E
A
V
T
N
V
V
K
H
S
----
Q
-------------
A
-------------
K
-----
T
C
R
V
D
I
Q
--
Q
L
W
K
E
V
V
I
T
V
S
D
D
G
T
F
-------------
K
-----------
G
E
--------------------------------------------------------------
H
------------
G
L
L
G
M
R
E
R
L
E
F
A
N
G
S
L
H
I
D
T
--
E
N
G
T
K
L
T
M
A
I
P
N
------------
6
PsiBlast_PDB
61.06
21%
-49
- C2 -
3EHH
2
DESK_BACSU
A:
[26-215]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
R
Q
R
M
A
R
D
L
V
D
T
L
G
Q
K
L
S
L
M
G
L
K
S
D
L
A
R
K
L
I
Y
K
D
P
E
Q
A
A
R
E
L
K
S
V
Q
Q
T
A
R
T
S
L
N
E
V
R
K
I
V
S
S
M
K
G
--
I
R
L
K
D
E
L
I
N
--
I
K
Q
I
L
-----
E
A
-
A
D
---
I
M
F
I
Y
E
--
E
E
-
K
W
P
E
N
I
S
L
L
N
E
---
N
I
L
S
M
C
L
K
E
A
V
T
N
V
V
K
H
S
----
Q
-------------
A
-------------
K
-----
T
C
R
V
D
I
Q
--
Q
L
W
K
E
V
V
I
T
V
S
D
D
G
T
F
-------------
K
-----------
G
---------------------------------------------------------------
H
------------
G
L
L
G
M
R
E
R
L
E
F
A
N
G
S
L
H
I
D
T
--
E
N
G
T
K
L
T
M
A
I
P
N
------------
4
PsiBlast_PDB
59.89
22%
-60
- C2 -
3GIF
2
DESK_BACSU
A:
[26-216]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
R
Q
R
I
A
R
D
L
E
D
T
L
G
Q
K
L
S
L
I
G
L
K
S
D
L
A
R
K
L
I
Y
K
D
P
E
Q
A
A
R
E
L
K
S
V
Q
Q
T
A
R
T
S
L
N
E
V
R
K
I
V
S
S
M
K
G
--
I
R
L
K
D
E
L
I
N
--
I
K
Q
I
L
-----
E
A
-
A
D
---
I
M
F
I
Y
E
--
E
E
-
K
W
P
E
N
I
S
L
L
N
E
---
N
I
L
S
M
C
L
K
E
A
V
T
N
V
V
K
H
S
----
Q
-------------
A
-------------
K
-----
T
C
R
V
D
I
Q
--
Q
L
W
K
E
V
V
I
T
V
S
D
D
G
T
F
-------------
K
-----------
G
E
--------------------------------------------------------------
H
------------
G
L
L
G
M
R
E
R
L
E
F
A
N
G
S
L
H
I
D
T
--
E
N
G
T
K
L
T
M
A
I
P
N
N
-----------
7
PsiBlast_PDB
59.23
21%
-47
- C2 -
3EHJ
2
DESK_BACSU
A:
[26-216]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
R
Q
R
M
A
R
D
L
V
D
T
L
G
Q
K
L
S
L
M
G
L
K
S
D
L
A
R
K
L
I
Y
K
D
P
E
Q
A
A
R
E
L
K
S
V
Q
Q
T
A
R
T
S
L
N
E
V
R
K
I
V
S
S
M
K
G
--
I
R
L
K
D
E
L
I
N
--
I
K
Q
I
L
-----
E
A
-
A
D
---
I
M
F
I
Y
E
--
E
E
-
K
W
P
E
N
I
S
L
L
N
E
---
N
I
L
S
M
C
L
K
E
A
V
T
N
V
V
K
H
S
----
Q
-------------
A
-------------
K
-----
T
C
R
V
D
I
Q
--
Q
L
W
K
E
V
V
I
T
V
S
D
D
G
T
F
-------------
K
-----------
G
E
E
N
-----------------------------------------
S
F
-----------------
H
------------
G
L
L
G
M
R
E
R
L
E
F
A
N
G
S
L
H
I
D
T
--
E
N
G
T
K
L
T
M
A
I
P
N
N
-----------
2
PsiBlast_PDB
58.28
22%
-53
- C2 -
3GIG
2
DESK_BACSU
A:
[26-216]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
R
Q
R
I
A
R
D
L
H
D
T
L
G
Q
K
L
S
L
I
G
L
K
S
D
L
A
R
K
L
I
Y
K
D
P
E
Q
A
A
R
E
L
K
S
V
Q
Q
T
A
R
T
S
L
N
E
V
R
K
I
V
S
S
M
K
G
--
I
R
L
K
D
E
L
I
N
--
I
K
Q
I
L
-----
E
A
-
A
D
---
I
M
F
I
Y
E
--
E
E
-
K
W
P
E
N
I
S
L
L
N
E
---
N
I
L
S
M
C
L
K
E
A
V
T
N
V
V
K
H
S
----
Q
-------------
A
-------------
K
-----
T
C
R
V
D
I
Q
--
Q
L
W
K
E
V
V
I
T
V
S
D
D
G
T
F
-------------
K
-----------
G
E
E
N
-----------------------------------------
S
F
S
----------------
H
------------
G
L
L
G
M
R
E
R
L
E
F
A
N
G
S
L
H
I
D
T
--
E
N
G
T
K
L
T
M
A
I
P
N
N
-----------
18
Fugue
51.03
10%
-53
- C2 -
1JM6
2
PDK2_RAT
A:
[11-374]
----------------------------------------
A
S
L
A
G
A
P
K
Y
I
E
H
F
S
K
F
S
P
S
P
L
S
M
K
Q
F
L
--
D
--
F
G
A
C
E
K
T
S
F
T
F
L
R
Q
E
L
P
V
R
L
A
N
I
M
K
E
I
N
L
L
P
D
R
V
L
S
T
-----------
P
S
V
Q
L
V
Q
S
W
Y
V
Q
S
L
L
D
I
M
E
F
L
D
K
D
P
E
D
H
R
T
L
S
Q
F
T
D
A
L
V
T
I
R
N
R
H
N
D
V
V
P
-
T
M
A
Q
G
V
L
E
Y
D
P
V
S
N
Q
N
I
Q
Y
F
L
D
R
F
Y
L
S
R
I
S
I
R
M
L
I
N
Q
H
T
L
I
F
D
--
P
K
H
I
G
S
I
D
P
N
C
S
V
S
D
V
V
K
-
D
A
Y
D
M
A
K
L
L
--
C
D
K
Y
Y
M
A
S
P
D
L
E
I
Q
E
V
N
A
T
-
N
A
T
-
Q
P
---
I
H
M
V
Y
-------
V
P
S
H
L
----
Y
---
H
M
L
F
E
L
F
K
N
A
M
R
A
T
V
E
S
H
----
E
-------------
S
-------------
S
LTL
P
-
P
I
K
I
M
V
A
--
L
G
E
E
D
L
S
I
K
M
S
D
R
G
G
G
-------------
V
-----------
P
L
R
K
-----------------------------------------
I
E
R
L
FSYMYSTAPTPAGF
G
Y
------------
G
L
P
I
S
R
L
Y
A
K
Y
F
Q
G
D
L
Q
L
F
S
M
E
G
F
G
T
D
A
V
I
Y
L
K
A
L
S
T
D
S
V
E
R
L
P
V
Y
9
Fugue
50.96
19%
-42
- C2 -
3EHG
11
A:
[1-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
R
L
K
D
E
L
I
N
I
K
Q
I
L
-
E
A
A
D
I
M
---
F
I
Y
E
E
E
K
W
P
E
-
N
I
S
L
L
N
----
E
---
N
I
L
S
M
C
L
K
E
A
V
T
N
V
V
K
H
S
----
Q
-------------
A
-------------
K
-----
T
C
R
V
D
I
Q
--
Q
L
W
K
E
V
V
I
T
V
S
D
D
G
T
F
-------------
K
-----------
G
E
E
N
-----------------------------------------
S
F
S
K
--------------
G
H
------------
G
L
L
G
M
R
E
R
L
E
F
A
N
G
S
L
H
I
D
T
E
N
--
G
T
K
L
T
M
A
I
P
N
------------
16
Fugue
48.37
14%
-54
- C2 -
4I5S
-
?
A:
[37-432]
N
N
N
Q
V
K
Q
L
N
A
K
V
R
S
L
I
T
G
H
Y
T
D
K
LKVEDNS
D
L
S
E
L
V
N
N
V
N
D
L
S
E
V
F
R
L
T
H
E
N
L
A
Q
E
K
N
R
L
T
S
I
L
S
Y
M
T
D
G
V
L
A
T
D
R
S
G
-
K
I
T
V
I
N
D
M
A
Q
K
Q
L
N
V
T
R
E
Q
A
L
E
C
N
I
L
D
I
L
D
D
D
S
Y
T
Y
N
D
L
I
T
K
T
P
E
I
V
L
T
R
R
--------
D
E
Y
D
E
F
I
T
L
R
I
R
F
A
L
N
R
R
E
S
G
F
I
S
G
L
I
A
V
L
H
D
A
T
E
Q
E
K
E
E
R
E
R
R
L
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
S
Y
L
E
A
L
D
D
G
A
L
T
E
S
--
V
A
P
S
F
I
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
L
L
S
L
S
R
S
H
L
D
V
E
L
T
N
F
T
A
F
M
N
Y
I
L
D
R
F
-
D
Q
I
-
Q
S
---
Q
Q
S
T
E
I
I
R
D
Y
P
D
K
S
V
W
I
----
E
I
D
T
D
K
M
T
Q
V
I
D
N
I
L
N
N
A
I
K
Y
S
P---
D
-------------
G
-------------
G
-----
K
V
T
I
T
M
Q
--
T
T
D
T
Q
L
I
L
S
I
S
D
Q
G
L
G
-------------
I
PKKDLPLIFDR
F
Y
R
V
-----------------------------------------
D
K
A
R
--------------
G
L
------------
G
L
A
I
A
K
E
I
V
K
Q
H
K
G
F
I
W
A
N
S
E
E
G
E
G
S
T
F
T
I
V
L
P
-------------
10
Fugue
48.08
25%
-45
- C2 -
3ZXQ
1
DOST_MYCTU
A:
[1-123]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
L
R
H
R
L
D
K
V
I
D
Q
L
A
I
P
A
-
L
H
---
T
T
V
Q
Y
T
G
P
L
S
-
V
V
D
T
V
L
----
A
---
N
H
A
E
A
V
L
R
E
A
V
S
N
A
V
R
H
A
----
N
-------------
A
-------------
T
-----
S
L
A
I
N
V
S
--
V
-
E
D
D
V
R
V
E
V
V
D
D
G
V
G
-------------
I
-----------
S
--------------------------------------------
G
D
I
T
--------------
E
S
------------
G
L
R
N
L
R
Q
R
A
D
D
A
G
G
E
F
T
V
E
N
M
P
T
G
G
T
L
L
R
W
S
A
P
L
R
-----------
15
Fugue
47.69
12%
-54
- C2 -
1GKZ
8
BCKD_RAT
A:
[38-378]
--------------------------------------------
V
R
L
T
P
T
M
M
L
Y
S
G
R
S
Q
D
G
S
H
L
L
K
S
--
G
R
Y
L
Q
Q
E
L
P
V
R
I
A
H
R
I
K
G
F
R
S
L
P
F
I
I
G
C
N
---
P
T
I
L
H
V
H
E
L
Y
I
R
A
F
Q
K
L
T
D
F
P
P
I
K
D
Q
A
D
E
A
Q
Y
C
Q
L
V
R
Q
L
L
D
D
H
K
D
V
V
T
L
L
A
E
G
L
R
E
S
R
K
H
I
E
D
E
------------
K
L
V
R
Y
F
L
D
K
T
L
T
S
R
L
G
I
R
M
L
A
T
H
H
L
A
L
H
E
D
K
P
D
F
V
G
I
--
I
C
T
R
L
S
P
K
K
I
I
E
K
W
V
D
F
A
R
R
L
C
E
H
K
Y
G
N
--
A
-------------
P
R
V
R
I
-
N
G
H
-
V
A
---
A
R
F
P
F
-------
I
P
M
P
L
----
D
---
Y
I
L
P
E
L
L
K
N
A
M
R
A
T
M
E
S
H
----
L
-------------
D
-------------
T
PY
N
V
P
D
V
V
I
T
I
A
--
N
N
D
V
D
L
I
I
R
I
S
D
R
G
G
G
IAHKDLDRVMDYH
F
-----------
T
T
A
P
-----------------------------------------
M
H
G
F
--------------
G
F
------------
G
L
P
T
S
R
A
Y
A
E
Y
L
G
G
S
L
Q
L
Q
S
L
Q
G
I
G
T
D
V
Y
L
R
L
R
H
I
D
G
R
E
E
------
31
HHSearch
44.74
24%
-15
- C2 -
1YSR
3
PRRB_MYCTU
A:
[38-149]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
I
I
V
G
L
----
P
---
A
G
L
R
L
A
V
D
N
A
I
A
N
A
V
K
H
G
----
G
-------------
A
-------------
T
-----
L
V
Q
L
S
A
V
--
S
S
R
A
G
V
E
I
A
I
D
D
N
G
S
G
-------------
V
-----------
P
E
G
E
R
Q
V
V
F
E
RFS---------------------------------------------------
L
------------
G
L
A
L
V
A
Q
Q
A
Q
L
H
G
G
T
A
S
L
E
N
S
P
L
G
G
A
R
L
V
L
R
L
P
G
P
-----------
11
Fugue
44.28
15%
-26
- C2 -
1ID0
2
A:
[1-146]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
L
H
P
V
A
P
L
L
D
N
L
T
S
A
L
-
N
K
V
-
Y
Q
RKG
V
N
I
S
L
D
I
S
P
E
-
I
S
F
V
G
E
----
Q
---
N
D
F
V
E
V
M
G
N
V
L
D
N
A
C
K
Y
C
----
L
---------------------------
E
-----
F
V
E
I
S
A
R
--
Q
T
D
E
H
L
Y
I
V
V
E
D
D
G
P
G
-------------
I
-----------
P
L
S
K
-----------------------------------------
R
E
V
I
FDRGQRVDTLRPGQ
G
V
------------
G
L
A
V
A
R
E
I
T
E
Q
Y
E
G
K
I
V
A
G
E
S
M
L
G
G
A
R
M
E
V
I
F
G
R
Q
H
----------
12
Fugue
42.46
16%
-37
- C2 -
1L0O
2
SP2AB_GEOSE
A:
[1-141]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
N
E
M
H
L
Q
F
S
A
R
S
E
N
-
E
S
F
-
A
R
---
V
T
V
A
A
F
V
A
Q
L
-
D
P
T
M
D
E
----
L
---
T
E
I
K
T
V
V
S
E
A
V
T
N
A
I
I
H
G
YNND
P
-------------
N
-------------
G
-----
I
V
S
I
S
V
I
--
I
E
D
G
V
V
H
L
T
V
R
D
E
G
V
G
-------------
I
-----------
P
D
I
E
-----------------------------------------
E
A
R
Q
--------------
P
L
FTTKPELERSGM
G
F
T
I
M
E
N
F
M
D
E
V
----
I
V
E
S
E
V
N
K
G
T
T
V
Y
L
K
K
H
I
V
K
S
---------
19
HHSearch
42.04
23%
-43
- C2 -
3EHH
2
DESK_BACSU
A:
[123-215]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
L
L
N
----
E
---
N
I
L
S
M
C
L
K
E
A
V
T
N
V
V
K
H
S
----
Q
-------------
A
-------------
K
-----
T
C
R
V
D
I
Q
--
Q
L
W
K
E
V
V
I
T
V
S
D
D
G
T
F
-------------
K
-----------
G
---------------------------------------------------------------
H
------------
G
L
L
G
M
R
E
R
L
E
F
A
N
G
S
L
H
I
D
T
E
--
N
G
T
K
L
T
M
A
I
P
N
------------
33
HHSearch
41.17
14%
-40
- C2 -
1I58
3
CHEA_THEMA
A:
[40-188]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
R
T
F
----
V
---
E
E
I
G
E
P
L
L
H
L
L
R
N
A
I
D
H
G
----
I
-------------
E
P
K
E
E
R
I
A
K
GKPP
I
G
-----
T
L
I
L
S
A
R
--
H
E
G
N
N
V
V
I
E
V
E
D
D
G
R
G
-------------
I
-----------
D
K
E
K
I
I
R
K
A
I
E
K
GLID
E
S
K
A
A
T
LS
D
Q
E
I
L
N
FLFVPGFS
T
K
E
K
V
S
E
V
S
G
R
--------------
G
V
------------
G
M
D
V
V
K
N
V
V
E
S
L
N
G
S
I
S
I
E
S
E
K
D
K
G
T
K
V
T
I
R
L
P
L
------------
27
HHSearch
40.97
23%
-33
- C2 -
3EHG
10
A:
[32-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
S
L
L
N
----
E
---
N
I
L
S
M
C
L
K
E
A
V
T
N
V
V
K
H
S
----
Q
-------------
A
-------------
K
-----
T
C
R
V
D
I
Q
--
Q
L
W
K
E
V
V
I
T
V
S
D
D
G
T
F
-------------
K
-----------
G
E
E
N
-----------------------------------------
S
F
S
K
--------------
G
H
------------
G
L
L
G
M
R
E
R
L
E
F
A
N
G
S
L
H
I
D
T
E
--
N
G
T
K
L
T
M
A
I
P
N
------------
8
PsiBlast_PDB
40.25
24%
-26
- C2 -
3EHG
10
A:
[25-125]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
E
-
K
W
P
E
N
I
S
L
L
N
E
---
N
I
L
S
M
C
L
K
E
A
V
T
N
V
V
K
H
S
----
Q
-------------
A
-------------
K
-----
T
C
R
V
D
I
Q
--
Q
L
W
K
E
V
V
I
T
V
S
D
D
G
T
F
-------------
K
-----------
G
E
E
N
-----------------------------------------
S
F
S
K
--------------
G
H
------------
G
L
L
G
M
R
E
R
L
E
F
A
N
G
S
L
H
I
D
T
--
E
N
G
T
K
L
T
M
A
I
P
N
------------
30
HHSearch
39.68
13%
-29
- C2 -
1B3Q
-
CHEA_THEMA
A:
[99-250]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
R
T
F
----
V
---
E
E
I
G
E
P
L
L
H
L
L
R
N
A
I
D
H
G
----
I
EP
K
E
E
R
I
A
K
GKPP
I
-------------
G
-----
T
L
I
L
S
A
R
--
H
E
G
N
N
V
V
I
E
V
E
D
D
G
R
G
-------------
I
-----------
D
K
E
K
I
I
R
K
A
I
E
KGLIDE
S
K
A
A
T
LS
D
Q
E
I
L
N
F
L
FVPGFS-------------------------
G
V
------------
G
M
D
V
V
K
N
V
V
E
S
L
N
G
S
M
G
I
E
S
E
K
D
K
G
T
K
V
T
I
R
L
P
L
T
L
A
---------
32
HHSearch
39.04
21%
-15
- C2 -
3SL2
2
A:
[34-153]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
L
Y
V
E
I
D
----
Q
---
D
K
I
T
Q
V
L
D
N
I
I
S
N
A
L
K
Y
S
----
P
-------------
E
G------------
G
-----
H
V
T
F
S
I
D
V
N
E
E
E
E
L
L
Y
I
S
V
K
D
E
G
I
G
-------------
I
-----------
P
K
K
D
VEKVFDRFYRVD-----------------------------
L
G
G
T
--------------
G
L
------------
G
L
A
I
A
K
E
M
V
Q
A
H
G
G
D
I
W
A
D
S
I
E
G
K
G
T
T
I
T
F
T
L
P
Y
K
E
----------