@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0058: (2015-12-12 )
MAEWKTDTEEVKKVVGRCREFKRSLQEEKCSPFIKDLDSYALKIIVERRKTEMQLEKAIGELKKAKSNEDDAKVALRVLQGASVVSWIWPPARIAATAAIVAAEAVLKFMKEDTEKCKRNVELLERMLEIYSNQAKASANLMNQAWEGIKKRLHFYTDKHQEFIRRLKQASDAIDNEYNFPTPGVLLEYDFERPAISYTPKKSVFNERLKDLRENFSASLYADLKDKIHHNALSNDDLERMIAFREQEFEKSLEDWMGAYSYDENPNDELDRMAISKEQELEKSLEDLMPSVLGVPSYNESLTLAKNRCVKNFKEALEGFTEKIKESPNDSNAINEAFDNLETELERATENLSQKIDPVLERNENYTQKALEYREFLESRKESFIVDEKNPYPEEVSFNEWRWAEFDSVFSAIVPLEDLNKTACAHHALKALQATLKDNDLGFDATELEQIAKGFIPRGYLWHFDANVLGNLALVREELLLGVKHTKGYSLWTEFLQKQN
Atome Classification :
(20 SA)
-----------...--....--..10........20.......---.30......-..40........50.--------.......60........-------70........80........90...----------.....100....-----...110..----..----...120-........130.......140.........150------.........160..-.....---------170.......180-.---.......190.......200.......210...--....220.......230-.......-..240..-------.......250.......260-----.........270--.-.......280.......290---...----....-----300........-310.......320.....----..330........340--....-...350.......360----.......--.370..-.....380.....-.--.390.......400...--------------....410.......--420....----------...430.......--440.....-..450-........460..-..--...470.......480.......490.---....----..500----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------MAE--WKT
D
--
T
E
E
V
K
K
V
V
G
R
C
R
E
F
K
R
S
L
Q
E
E
---
K
C
S
P
F
I
K
D
L
-
D
S
Y
A
L
K
I
I
V
E
R
R
K
T
E
--------
M
Q
L
E
K
A
I
G
E
L
K
K
AKSNE-------
D
D
A
K
V
A
L
R
V
LQGA
S
V
V
S
WIWP
P
A
R
I
----------
A
A
T
A
A
I
V
A
A
E
A
V
-----
L
K
F
M
K
E
D
T
----
E
K
----
C
K
R
N
V
--
E
L
L
E
R
M
L
E
I
YSNQA
K
A
S
A
N
--
L
M
N
Q
A
W
E
G
I
K
--------
K
R
L
H
F
Y
T
D
K
H
Q
E
F
I
-
R
R
L
K
Q
---------
A
S
DAIDNEYNFP--T---P
G
V
L
L
E
Y
DFERPAISYT
P
K
K
S
V
F
N
E
R
L
K
D
L
R
E
N
--
F
S
A
S
L
Y
A
D
L
K
D
K
I
HH---NAL
S
N
D
D
-
L
E
R
--
M
I
-------
A
F
R
E
Q
E
F
E
K
S
L
E
D
W
M
G
AY-------SYDENPN
D
E
L
D
---
R
-
M
AI
S
K
E
Q
E
L
E
K
S
L
E
D
L
M
P
S
V
---LGV----PSYN-----E-
S
L
T
L
A
K
N
R
C
-
V
K
N
F
K
E
A
L
E
G
F
T
E
K
I
KES----PNDS-
N
A
I
N
E
A
F
D
N
L
E
--
T
E
L
E
-
R
A
T
E
N
L
S
Q
K
I
D
P
V
L
E-----RNEN
Y
T
Q
--
K
A
L
E
Y
R
-
E
F
L
E
S
R
K
E
S
F
IVD-E--KNPYPEEVSFNEW
R
W
A
E
--------------
F
D
S
V
F
S
A
IV
P
L
E
DL--
N
K
T
A
C
A
H
----------
H
A
L
K
A
L
Q
A
T
LKDN--DLGF
D
A
T
E
-
L
E
Q
I
--
A
K
G
FIPR
G
Y
L
W
HF-
D
A
--
N
V
L
G
N
L
A
L
V
R
E
E
L
L
L
G
VKHTK
G
Y
S
L
W
T
---
E
F
L
Q----KQN------------
35
Fugue
91.46
18%
-33
- C2 -
4XGC
1
ORC5_DROME
E:
[1-458]
-----------
M
E
A
--
I
C
S
S
--
L
E
P
L
F
P
C
--------
R
E
A
A
I
E
---
T
L
G
E
L
I
G
D
S
S
E
T
Y
P
S
A
I
Y
L
F
G
H
-------------------------
S
G
T
-------
G
K
T
A
L
T
R
A
F
L
K
E
C
G
K
R
----
Q
N
V
R
T
----------
A
H
L
N
A
I
------------------------
E
----
C
Y
T
T
K
--
I
M
L
E
I
L
L
D
S
L
A
P
D
Q
G
D
A
L
K
--
V
------------------------
D
N
M
L
D
F
V
-
E
Q
L
R
R
---------
Q
A
A
T
-----
R
V
E
--
D
---
Q
G
F
L
I
A
V
D
---
N
A
E
R
L
R
D
M
D
A
N
V
L
P
V
L
L
R
L
Q
E
L
--
T
N
L
N
L
C
V
I
L
L
S
Q
L
P
F
---
E
K
F
Y
N
K
T
G
L
S
E
--
I
V
-------
C
L
H
L
A
Q
Y
N
K
A
E
T
Q
R
I
L
G
S
-------
D
F
Q
Q
V
R
N
Q
L
L
E
QK
K
R
-
L
E
I
C
Q
E
A
V
T
E
D
F
Y
N
N
Y
L
N
L
F
---
L
S
V
F
YKA
C
R
D
V
-----
P
-
E
L
Q
L
T
A
R
K
C
-
L
S
T
Y
L
E
P
V
L
D
G
T
S
R
L
------------------
W
R
H
I
A
--
G
P
L
R
-
S
A
L
T
Q
I
Y
M
R
I
E
S
L
--------
E
L
P
Y
Y
A
--
K
F
L
L
I
A
-
A
F
L
A
S
H
N
A
A
--
K
Q
-
D
--
K
R
L
F
S
T
T
L
G
P
K
S
F
S
I
D
R
--------------
L
L
A
I
F
Y
A
I
L
E
------
E
K
V
G
L
T
C
----------
N
L
L
S
Q
I
S
T
L
V
H
L
N
--
L
L
S
F
V
S
G
E
--
Q
N
I
--
M
E
G
-----------
S
A
--
R
L
Q
C
T
I
G
L
---
E
F
V
L
Q
I
G
K
V
V
G
F
N
V
-
R
---
Q
Y
L
C
----
D
--------------
40
Fugue
76.82
16%
-6
* C9 *
2BVL
8
TOXB_PEPDI
A:
[1-543]
MSLVN
R
K
Q
L
E
K
M
A
N
VR
F
R
T
Q
--
E
D
E
Y
V
A
I
L
D
A
L
E
E
Y
H
N
M
S
E
N
T
---
V
V
E
K
Y
L
K
L
K
-
D
I
N
S
L
T
D
I
C
I
D
T
Y
K
K
--------
S
G
R
N
K
A
L
K
K
F
K
E
Y
L
V
T
E
-------
V
L
E
L
K
N
N
N
L
T
P
V
E
K
N
L
H
F
V
W
I
G
G
Q
I
N
D
--------
T
A
I
N
Y
I
N
Q
W
K
D
V
N
SD
Y
N
V
N
V
F
Y
D
S
N
AFL
I
N
T
----
L
K
K
T
V
V
E
S
A
I
N
D
T
L
E
S
F
R
E
N
L
N
D
P
R
F
--
D
Y
N
K
F
F
---
R
--------
K
R
M
E
I
I
Y
D
K
Q
K
N
F
I
-
N
Y
Y
K
A
---------
Q
R
E
E
---
N
P
E
L
I
--
I
---
D
D
I
V
K
T
Y
L
S
N
E
Y
S
K
E
I
D
E
L
N
T
Y
I
E
E
S
L
N
K
I
T
Q
N
SG
N
D
V
R
N
F
G
E
F
K
N
G
E
S
F
---
N
L
Y
E
Q
E
L
-
V
E
R
WN
L
A
-------
A
A
S
D
I
L
R
I
S
A
L
K
E
I
G
G
M
Y
L
D
VDMLP
G
I
Q
P
D
L
F
E
S
I
E
---
K
P
S
S
V
T
V
D
F
W
E
M
T
K
L
E
A
I
M
K
Y
K
---
E
Y
I
----
P
E
Y
T
S----
E
-
H
F
D
M
L
D
E
E
V
-
Q
S
S
F
E
S
V
L
A
--------
S
----
K
S
D
K
-
S
E
I
F
S
S
L
G
D
M
E
A
-
S
P
L
E
V
K
I
A
F
N
S
K
G
I
I
N
Q
G
L
I
S
V
K
DS
Y
C
S
N
L
I
V
--
K
Q
I
E
N
R
Y
K
I
L
N
N
S
L
N
P
A
I
S
E
-
D
--
N
D
F
N
T
T
T
N
T
F
I
D
S
I
M
A
E
--------------
A
N
A
D
N
G
R
F
--
M
M
E
L
--
G
K
Y
L
R
V
G
----------
F
F
P
D
-
V
K
T
T
I
N
L
S
--
G
P
E
A
Y
A
A
A
-
Y
Q
D
L
--
L
M
-
F
K
E
G
S
M
N
I
H
L
-
I
E
--
A
D
L
R
N
F
E
I
S
K
T
N
I
S
Q
S
T
E
Q
E
M
A
-
S
L
W
S
FD
D
A
R
A
K
----
A
Q
F
E
E
Y
K
R
N
Y
F
E
GAL
39
Fugue
71.73
15%
9
- C3 -
4PW2
1
?
A:
[72-585]
----------R
Y
E
E
--
I
D
C
L
--
I
N
D
D
A
T
I
K
G
R
R
E
G
S
E
V
Y
M
P
-------
F
S
W
M
E
K
Y
-
F
E
V
Y
G
K
V
V
Q
Y
D
G
Y
D
R
--------
F
E
F
S
H
S
Y
S
K
V
Y
A
Q
R
E
Q
Y
-------
H
P
N
G
V
F
M
S
-
F
E
G
Y
N
V
----
E
V
R
D
R
V
----------
K
C
I
S
G
V
---
E
G
V
-----
P
L
S
T
Q
W
G
P
----
Q
G
----
Y
F
Y
A
I
--
Q
I
A
Q
Y
G
L
S
H
Y
S
K
N
L
T
E
R
P
P
---
H
V
E
V
Y
D
T
A
E
--------
E
R
S
A
W
T
V
P
K
G
C
S
L
T
-
R
V
Y
D
K
---------
T
R
A
T
S
V
R
E
F
S
A
P
EN
S
---
E
G
V
S
L
P
L
G
--------
N
T
K
D
F
I
I
S
F
D
L
K
-
F
T
S
N
--
G
S
V
S
V
I
L
E
T
T
E
K
G
P
P
---
F
V
I
H
Y
V
T
-
T
T
Q
--
L
I
-------
L
L
K
D
R
D
I
T
Y
G
I
G
P
R
T
T
W
T
-------
T
V
T
R
D
L
L
T
D
L
----
R
-
K
G
I
G
L
S
N
T
K
A
V
K
A
T
K
T
M
P
R
R
---
V
V
K
----
L
V
V
H
G
T
G
T
I
D
-
N
I
T
I
S
T
T
S
H
-
M
A
A
F
Y
A
A
S
D
W
L
V
R
N
Q
D
E
R
GGWP
I
M
V
T
-
R
K
L
G
E
G
F
R
A
L
E
--
P
G
W
Y
-
S
A
M
A
Q
-
G
Q
A
M
S
-
T
L
V
-----
R
A
Y
L
M
T
---
K
D
D
R
Y
L
-
K
A
A
L
R
A
T
G
P
F
K
L
P
-
S
--
E
Q
H
G
V
K
A
V
F
M
N
K
Y
D
W
Y
E
EYPTIPSSFV----
L
N
G
F
I
Y
S
L
I
G
L
F
D
L
--
A
Q
T
A
G
E
K
LG
R
D
A
G
Q
L
Y
S
K
G
M
E
S
L
K
V
M
L
P
L
Y
--
D
T
G
S
G
T
I
Y
D
L
R
H
F
--
I
L
G
T
A
P
N
L
A
R
W
D
Y
-
H
T
--
T
H
I
N
Q
L
Q
L
L
-
G
T
I
D
N
S
P
I
F
R
D
S
V
K
R
W
K
---
S
Y
L
K
GGRA
K
H
N
------------
41
Fugue
68.97
14%
-9
- C9 -
4K5Y
7
CRFR1_HUMAN (first)
A:
[13-423]
--------H
Y
H
V
A
A
--
I
I
N
Y
--
L
G
H
C
I
S
L
V
A
L
L
V
A
F
V
L
F
L
R
A
R
---
S
I
R
C
L
R
N
I
I
-
H
A
N
L
I
A
A
F
I
L
R
N
A
T
W
--------
F
V
V
Q
L
T
M
-
S
P
E
V
H
Q
S
N
V
-------
G
W
C
R
L
V
T
A
A
Y
N
Y
F
H
V
T
N
F
F
W
M
F
G
E
G
----------
C
Y
L
H
T
A
I
V
L
T
N
I
-----
F
E
M
L
R
I
D
E
----
G
L
----
R
L
K
I
Y
--
K
D
T
E
G
Y
Y
T
I
-------------------
G
I
G
--------
H
L
L
T
K
S
P
S
---------
L
S
V
---------
A
K
S
E
L
D
K
A
I
G
R
N
--
S
---
N
G
V
I
----------------------------------------------------
T
K
D
E
-
A
E
K
--
L
F
-------
N
Q
D
V
D
A
A
V
R
G
I
L
R
------------------
N
A
K
L
K
---
P
-
V
Y
D
S
L
D
A
V
R
R
S
A
L
I
N
M
V
F
Q
M
--------------------------
G
E
T
G
-
V
A
G
F
T
N
S
L
R
M
L
Q
Q
K
--------------
R
W
D
E
A
A
V
N
L
A
K
-
S
R
W
Y
-
N
Q
T
P
N
R
A
K
R
V
I
A
T
F
R
-----
T
G
T
----------
W
D
-
A
Y
D
R
L
R
A
W
M
F
I
C
I
G
W
--
G
V
P
F
P
I
I
V
A
W
A
I
G
K
L
Y
Y
DNEKCWAGKRPGVY
T
D
Y
I
Y
Q
G
P
M
A
L
V
L
L
--
I
N
F
I
F
L
F
----------
N
I
V
R
I
L
M
T
K
L
R
A
S
TT
S
E
T
I
Q
A
R
K
-
A
V
K
A
--
T
L
V
L
L
P
L
L
G
I
T
Y
M
-
L
A
F
V
N
E
V
S
R
V
V
F
I
Y
F
N
A
F
L
E
S
F
Q
G
F
F
V
S
V
F
A
---
C
F
L
N
----
S
--------------
37
Fugue
68.23
17%
8
- C4 -
4J0D
6
?
A:
[22-491]
-------SMSN
R
L
I
--
F
D
A
D
W
L
V
P
E
Q
V
Q
V
A
G
Q
A
I
Q
Y
Y
A
A
R
N
I
Q
YVQ
H
P
V
A
A
I
Q
V
L
-
N
V
F
V
P
A
A
Y
L
H
G
S
S
V
N
GYQRA
T
A
P
I
L
M
P
N
T
V
G
G
Y
L
P
G
P
A
D
D
PQRVTWP
T
N
A
G
T
I
Q
Q
A
L
K
R
G
Y
V
V
V
A
A
G
I
R
G
R
T
TVDKSGQRVG
Q
A
P
A
F
I
V
D
M
K
A
A
-----
I
R
Y
V
K
Y
N
Q
----
G
R
LPGD
A
N
R
I
I
--
T
N
G
T
S
A
G
G
A
T
S
A
L
A
G
A
S
G
N
SA
Y
F
E
P
A
L
T
A
L
G
AAPATDDI
F
A
V
S
A
Y
C
P
I
H
N
------
L
E
H
---------
A
D
M
A
Y
E
W
Q
F
N
G
I
--
N
---
D
W
H
R
Y
Q
P
V
-
A
G
T
T
K
N
G
R
P
K
F
E
P
V
S
G
Q
L
T
V
E
E
Q
A
--
L
S
L
A
L
K
A
Q
F
S
T
Y
L
N
Q
---
L
K
L
T
A
S
D
-
G
T
H
--
L
T
L
N
EAGMG
S
F
R
D
V
V
R
Q
L
L
I
S
S
A
Q
T
A
F
-------
D
-
Q
G
T
D
I
H
K
Y
A
---
G
-
F
V
V
T
G
N
Q
V
T
D
L
D
L
S
A
Y
L
K
S
L
T
R
M
K
A
V
----
P
A
F
D
-----
Q
L
D
L
T
S
P
E
N
N
L
-
F
G
D
A
T
A
K
A
K
H
F
T
A
L
A
Q
T
R
----
S
T
----------------
V
T
A
Q
-
L
A
D
A
E
L
I
Q
A
I
N
P
L
S
Y
-----
L
T
T
T
S
S
Q
VA
K
H
W
R
I
R
-
H
G
A
A
D
R
D
T
S
F
-----------------------------------------
A
I
P
I
I
L
A
I
M
L
E
--
N
H
G
Y
G
I
D
----------
F
A
L
P
W
D
I
P
H
S
G
D
Y
--
D
L
G
D
L
F
S
W
-
I
D
G
L
--
C
Q
---------------------------------------------------------------------
42
Fugue
67.22
14%
-21
- C5 -
3HOT
5
MOS1T_DROMA
A:
[5-345]
-----------------
V
P
N
--
K
E
Q
T
R
T
V
L
I
F
C
F
H
L
K
K
T
------------
A
A
E
S
-
H
R
M
L
V
E
A
F
G
E
Q
V
P
T
V
--------
K
T
C
E
R
W
F
Q
R
F
K
S
G
D
F
D
V
-------
D
D
K
E
H
G
------------------------------
K
P
P
K
R
Y
E
D
A
E
L
-----
Q
A
L
L
D
E
D
D
----
A
Q
----
T
Q
K
Q
L
--
A
E
Q
-------------------
L
E
V
S
Q
Q
A
V
S
--------
N
R
L
R
E
M
G
K
I
Q
K
--------------------------------------------------
V
G
R
W
V
P
H
E
L
N
E
R
Q
M
E
R
R
K
N
--
T
C
E
I
L
L
S
R
Y
K
R
K
-----------
S
F
-
L
H
R
--
I
V
-------
T
G
D
E
K
W
I
F
F
V
N
P
K
R
K
K
S
Y
-------
V
D
P
G
Q
P
A
T
------------
S
T
A
R
P
N
R
F
G
K
K
T
M
L
C
V
---
W
W
D
----
Q
S
G
V
-----
I
-
Y
Y
E
L
L
K
-------------------
P
G
E
----
T
V
N
A
-
A
R
Y
Q
Q
Q
L
I
N
L
N
--
R
A
L
Q
-
R
K
R
P
E
Y
Q
H
R
V
--
I
F
L
-----
H
D
N
A
P
S
H
--
T
A
R
A
V
R
-
D
T
L
E
T
L
N
W
E
V
L
--------
P
H
A
A
Y
S
----------------------------------
P
D
L
--
A
--
P
S
D
Y
----------
H
L
F
A
S
M
G
H
A
L
A
E
Q
--
R
F
D
-
S
Y
E
S
-
V
K
K
W
--
L
D
E
W
F
A
A
-----
K
-
D
D
--
E
F
Y
W
R
G
I
H
K
L
P
E
R
W
E
K
C
V
A
S
D
G
K
Y
F
E
---------------------------
33
Fugue
64.04
14%
-1
* C7 *
4E40
-
?
A:
[3-247]
------------
G
E
--
I
K
V
E
--
L
E
D
-
S
D
D
V
A
A
A
C
E
L
R
A
Q
L
A
--------
G
V
S
I
A
S
-
G
I
L
L
R
P
A
V
I
R
N
A
T
T
E
--------
F
S
R
K
K
S
E
D
I
L
A
K
G
G
A
A
V
-------
E
R
A
S
A
A
V
D
R
V
S
G
L
D
K
T
N
----
E
T
A
Q
----------
K
V
R
K
A
A
A
V
A
H
H
A
-----
L
E
H
V
K
E
E
V
----
E
I
----
V
A
K
K
V
--
N
E
I
I
E
L
T
A
G
A
T
E
H
A
K
G
A
K
A
--
N
G
D
A
S
A
V
K
V
S
--------
N
L
L
A
R
A
K
E
S
E
N
Q
Y
V
-
K
E
A
A
E
E
C
S
E
S
T
N
YD
V
T
A
K
S
L
A
A
A
L
D
K
--
L
---
P
G
V
K
E
D
N
A
V
K
T
T
F
Q
S
I
L
T
S
L
D
N
L
D
K
D
V
K
S
V
E
Q
R
--
A
-----
E
E
L
E
T
A
L
E
K
---
A
E
R
Q
L
E
K
-
A
E
K
--
A
A
-------
E
E
A
E
T
E
S
S
K
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
61.85
13%
2
- C7 -
3EDV
5
SPTB2_HUMAN
A:
[2-323]
----------------------------------------------------------------
S
H
M
R
H
R
L
--------
F
Q
L
N
R
E
V
D
D
L
E
Q
W
I
A
E
R
-------
E
V
V
A
G
S
H
E
L
G
Q
D
-------
Y
E
H
V
T
M
----------
L
Q
E
R
F
R
E
F
A
R
D
T
-----
G
N
I
G
Q
E
R
V
----
D
T
----
V
N
H
L
A
--
D
E
L
I
N
S
G
H
S
D
A
A
T
I
A
E
W
K
D
--
G
L
N
E
A
W
A
D
L
L
--------
E
L
I
D
T
R
T
Q
I
L
A
A
S
Y
-
E
L
H
K
F
---------
Y
H
D
A
K
E
I
F
G
R
I
Q
--
D
---
K
H
K
K
L
P
E
E
L
G
R
D
Q
N
T
V
E
T
L
Q
R
M
H
T
T
F
E
H
D
I
-
Q
A
--
L
G
T
Q
V
R
Q
L
Q
E
D
A
A
R
L
---
Q
A
A
Y
A
G
D
-
K
A
D
--
D
I
-------
Q
K
R
E
N
E
V
L
E
A
W
K
S
L
L
------------
D
A
C
E
S
R
R
V
R
---
L
-
V
D
T
G
D
K
F
R
F
F
S
M
V
R
D
L
M
L
W
M
---
E
D
V
----
I
R
Q
I
-----
E
-
A
Q
E
K
P
R
D
V
S
S
V
E
L
L
M
N
N
H
Q
G
I
K
A
E
I
D
A
R
----
N
D
S
F
-
T
T
C
I
E
L
G
K
S
L
L
--
A
R
K
H
-
Y
A
S
E
E
I
K
E
K
L
L
Q
L
T
E
-----
K
R
K
E
M
I
D
--
K
W
E
D
R
W
-
E
W
L
R
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
52.90
25%
5
- C8 -
2YY5
2
SYW_MYCPN
A:
[192-315]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
M
D
L
F
D
P
T
K
K
M
S
K
S
--
S
K
N
Q
--
N
G
V
-------------
I
Y
L
D
D
P
K
E
V
V
V
K
K
I
R
Q
---------
A
T
T
D
S
F
N
K
I
R
F
A
--
S
KTQ
P
G
V
T
N
M
L
T
I
L
K
A
L
L
K
E
P
V
N
Q
S
L
T
N
Q
L
G
N
D
L
E
A
Y
--
F
S
T
K
S
Y
L
D
L
K
N
A
L
T
E
A
T
V
N
L
L
V
N
I
Q
-
R
K
R
--
E
Q
-------
I
S
R
E
Q
V
F
N
C
L
Q
A
G
K
N
Q
A
Q
-------
A
T
A
R
T
T
L
A
L
F
Y
---
D
-
G
F
G
L
G
S
Q
N
I
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
52.40
7%
15
- C6 -
4U0R
-
?
A:
[160-504]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
D
I
L
Q
E
K
E
G
H
L
D
-
F
V
I
I
P
---------
H
Y
T
F
L
D
Y
Y
K
H
L
S
--
Y
---
N
S
I
Y
H
K
S
S
T
Y
G
K
Y
I
A
V
D
A
F
I
K
K
I
N
E
A
Y
D
K
V
K
S
K
--
C
N
D
I
K
N
D
L
I
A
T
I
K
K
L
---
E
H
P
Y
F
K
K
-
M
M
D
--
E
Y
-------
N
T
K
K
K
K
L
I
K
C
I
K
N
-------------
H
E
N
D
F
N
K
I
C
M
---
D
-
M
K
N
Y
G
T
N
L
F
E
Q
L
S
C
Y
N
N
N
F
C
---
N
T
N
----
G
I
R
Y
-----
H
-
Y
D
E
Y
I
H
K
L
I
-
L
S
V
K
S
K
N
L
N
K
D
L
S
D
M
T
N
I
----
L
Q
Q
S
-
E
L
L
L
T
N
L
N
K
K
M
GS
Y
I
Y
I
-
D
T
I
K
F
I
H
K
E
M
K
H
I
F
N
-----
R
I
E
Y
H
T
K
--
I
I
N
D
K
T
-
K
I
I
Q
D
K
I
K
L
N
I
W
R
-
T
F
Q
K
D
E
L
L
K
R
I
L
D
M
S
N
E
Y
S
L
--------------
F
I
T
S
D
H
L
R
Q
M
L
Y
N
T
F
Y
S
K
E
K
H
L
N
----------
N
I
F
H
H
L
I
Y
V
L
Q
M
K
----------------------------------------------------------------------------------------
18
PsiBlast_PDB
51.34
28%
73
- C8 -
4GNT
4
1433B_MOUSE
A:
[27-98]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
K
A
V
T
E
Q
G
H
E
L
----
S
N
E
E
R
N
L
L
S
V
A
Y
K
N
V
---
V
G
A
R
-
R
S
S
W
R
V
I
S
S
I
E
Q
K
T
E
-----
R
N
E
K
K
Q
Q
--
M
G
K
E
Y
R
-
E
K
I
E
A
E
L
Q
D
I
C
N
D
-
V
--
L
E
L
L
D
K
Y
L
I
L
N
A
T
Q
A
E
S
--------------
K
V
F
Y
L
K
M
K
G
D
Y
F
R
Y
--
L
S
E
V
A
S
G
----------
E
N
K
Q
T
T
V
S
N
S
Q
Q
A
--
Y
Q
E
A
F
E
I
S
-
K
K
E
M
--
Q
P
T
H
P
I
R
L
G
L
A
L
N
-
F
S
--
V
F
Y
Y
E
I
L
N
S
P
E
K
A
C
S
L
A
K
T
A
F
D
E
A
I
A
E
---
L
D
T
L
----
N
E
E
------------
23
HHSearch
49.46
16%
48
- C8 -
1EQ1
-
APL3_MANSE
A:
[16-110]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
E
F
Q
K
T
F
S
E
Q
F
N
S
L
---
V
N
S
----
K
N
T
Q
-----
D
-
F
N
K
A
L
K
D
G
S
--
D
S
V
L
Q
Q
L
S
A
F
S
S
S
L
Q
G
A
----
I
S
D
A
N
G
K
A
K
E
A
L
E
Q
A
R
--
Q
N
V
E
-
K
T
A
E
E
L
R
K
A
-
H
P
-----------
D
V
E
K
--
E
A
N
A
F
K
-
D
K
L
Q
A
A
V
Q
T
T
V
Q
E
-
S
--
Q
K
L
A
K
E
V
A
S
N
M
E
E
T
N
K
K
--------------
L
A
P
K
I
K
Q
A
Y
D
D
F
V
K
--
H
A
E
E
V
Q
K
----------
K
L
H
E
A
A
T
K
Q
--------------------------------------------------------------------------------------------
16
PsiBlast_PDB
48.72
28%
75
- C8 -
2BQ0
-
1433B_HUMAN
A:
[27-98]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
K
A
V
T
E
Q
G
H
E
L
----
S
N
E
E
R
N
L
L
S
V
A
Y
K
N
V
---
V
G
A
R
-
R
S
S
W
R
V
I
S
S
I
E
Q
K
T
E
-----
R
N
E
K
K
Q
Q
--
M
G
K
E
Y
R
-
E
K
I
E
A
E
L
Q
D
I
C
N
D
-
V
--
L
E
L
L
D
K
Y
L
I
P
N
A
T
Q
P
E
S
--------------
K
V
F
Y
L
K
M
K
G
D
Y
F
R
Y
--
L
S
E
V
A
S
G
----------
D
N
K
Q
T
T
V
S
N
S
Q
Q
A
--
Y
Q
E
A
F
E
I
S
-
K
K
E
M
--
Q
P
T
H
P
I
R
L
G
L
A
L
N
-
F
S
--
V
F
Y
Y
E
I
L
N
S
P
E
K
A
C
S
L
A
K
T
A
F
D
E
A
I
A
E
---
L
D
T
L
----
N
E
E
------------
17
PsiBlast_PDB
48.09
28%
80
- C8 -
2C23
1
1433B_HUMAN
A:
[27-98]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
K
A
V
T
E
Q
G
H
E
L
----
S
N
E
E
R
N
L
L
S
V
A
Y
K
N
V
---
V
G
A
R
-
R
S
S
W
R
V
I
S
S
I
E
Q
K
----------
K
K
Q
Q
--
M
G
K
E
Y
R
-
E
K
I
E
A
E
L
Q
D
I
C
N
D
-
V
--
L
E
L
L
D
K
Y
L
I
P
N
A
T
Q
P
E
S
--------------
K
V
F
Y
L
K
M
K
G
D
Y
F
R
Y
--
L
S
E
V
A
S
G
----------
D
N
K
Q
T
T
V
S
N
S
Q
Q
A
--
Y
Q
E
A
F
E
I
S
-
K
K
E
M
--
Q
P
T
H
P
I
R
L
G
L
A
L
N
-
F
S
--
V
F
Y
Y
E
I
L
N
S
P
E
K
A
C
S
L
A
K
T
A
F
D
E
A
I
A
E
---
L
D
T
L
----
N
E
E
------------
2
PsiBlast_PDB
44.65
38%
-20
- C8 -
3LSP
2
?
A:
[14-66]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
L
M
S
A
A
R
H
L
M
E
S
--
G
R
G
F
G
S
L
S
-
L
R
E
V
T
R
A
A
G
I
V
P
A
G
F
Y
R
H
F
S
D
M
--
D
Q
L
G
-
L
A
L
V
A
E
V
D
E
T
F
R
A
T
L
R
A
V
R
R
N
E
---
F
E
L
G
----
G
L
I
------------
7
PsiBlast_PDB
43.71
31%
175
- C8 -
4WSU
-
?
B:
[42-85]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
A
I
D
G
I
T
N
K
V
N
S
I
----
I
N
K
M
-
N
T
Q
F
E
A
V
D
H
E
F
--
S
N
L
E
-
R
R
I
G
N
L
N
K
R
M
E
D
G
F
L
-----
D
V
W
T
Y
N
A
--
E
L
L
V
L
L
-
E
N
E
R
T
L
D
L
H
D
A
N
V
-
K
--
N
L
Y
E
K
V
K
S
Q
L
R
D
N
A
N
D
L
--------------
G
N
G
C
F
E
F
W
H
K
C
D
N
E
--
C
M
E
S
V
K
N
----------
G
T
Y
D
Y
P
K
Y
Q
K
E
S
K
--
L
N
R
-----------------------------------------------------------------------------------
3
PsiBlast_PDB
43.51
38%
-22
- C8 -
3LSR
1
?
A:
[14-66]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
L
M
S
A
A
R
H
L
M
E
S
--
G
R
G
F
G
S
L
S
-
L
R
E
V
T
R
A
A
G
I
V
P
A
G
F
Y
R
H
F
S
D
M
--
D
Q
L
G
-
L
A
L
V
A
E
V
D
E
T
F
R
A
T
L
R
A
V
R
R
N
E
---
F
E
L
G
----
G
L
I
------------
9
PsiBlast_PDB
43.49
31%
177
- C8 -
4XKF
-
?
B:
[42-85]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
A
I
D
G
I
T
N
K
V
N
S
I
----
I
N
K
M
-
N
T
Q
F
E
A
V
D
H
E
F
--
S
N
L
E
-
R
R
I
G
N
L
N
K
R
M
E
D
G
F
L
-----
D
V
W
T
Y
N
A
--
E
L
L
V
L
L
-
E
N
E
R
T
L
D
L
H
D
A
N
V
-
K
--
N
L
Y
E
K
V
K
S
Q
L
R
D
N
A
N
D
L
--------------
G
N
G
C
F
E
F
W
H
K
C
D
N
E
--
C
M
E
S
V
K
N
----------
G
T
Y
D
Y
P
K
Y
Q
K
E
S
K
--
L
N
R
Q
G
I
--------------------------------------------------------------------------------
10
PsiBlast_PDB
43.34
31%
174
- C8 -
4XKD
-
?
B:
[42-85]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
A
I
D
G
I
T
N
K
V
N
S
I
----
I
N
K
M
-
N
T
Q
F
E
A
V
D
H
E
F
--
S
N
L
E
-
R
R
I
G
N
L
N
K
R
M
E
D
G
F
L
-----
D
V
W
T
Y
N
A
--
E
L
L
V
L
L
-
E
N
E
R
T
L
D
L
H
D
A
N
V
-
K
--
N
L
Y
E
K
V
K
S
Q
L
R
D
N
A
N
D
L
--------------
G
N
G
C
F
E
F
W
H
K
C
D
N
E
--
C
M
E
S
V
K
N
----------
G
T
Y
D
Y
P
K
Y
Q
K
E
S
K
--
L
N
R
Q
G
---------------------------------------------------------------------------------
5
PsiBlast_PDB
43.30
34%
185
- C8 -
4JUM
-
?
B:
[42-85]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
A
I
D
G
I
T
N
K
V
N
S
I
----
I
N
K
M
-
N
T
Q
F
E
A
V
G
R
E
F
--
S
N
L
E
-
R
R
I
E
N
L
N
K
K
M
E
D
G
F
L
-----
D
V
W
T
Y
N
A
--
E
L
L
V
L
M
-
E
N
E
R
T
L
D
F
H
D
S
N
V
-
K
--
N
L
Y
D
K
V
R
L
Q
L
R
D
N
A
K
E
L
--------------
G
N
G
C
F
E
F
Y
H
K
C
D
D
E
--
C
M
E
S
V
K
N
----------
G
T
Y
D
Y
P
Q
Y
S
E
E
A
R
--
L
N
R
-----------------------------------------------------------------------------------