@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0153: (2015-12-12 )
MAGRMELKNIISETLNEIEKMAKTIDDGFNTAQKTPSFFKTPSHLQNTPNSKNANTPLEPKNAAKIETQEKITEEKEEAKEIITEEIVQENPTQALIPNERVFLKGLLERTLVLFKGMQALEEKEALKRLDLVARFLQYQLSVLEKRLESLERENTE
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10..-......20........30........40........50........60........70........80........90........100--..-......110.....-----..120.......130--..-....--...140.......150.....---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MA
G
R
M
E
L
K
N
I
I
S
E
-
T
L
N
E
I
E
K
M
A
K
T
I
D
DGFN
T
A
QKTPSFFKT
P
S
H
LQNTPNSKNANTPLEPKNAAKI
E
T
Q
E
K
I
T
E
E
K
E
E
A
K
E
I
I
T
E
E
I
V
Q
ENPTQALIPN
E
R
---
V
F
-
L
K
G
L
L
E
R
T
L
V
L
F
K
G
-----
M
Q
A
L
E
E
K
E
A
L
K
R
L
----
D
L
-
V
A
R
F
--
L
Q
Y
Q
L
S
V
L
E
K
R
L
E
S
L
E
RENTE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
79.27
17%
18
* C8 *
4UI9
-
APC4_HUMAN
I:
[6-757]
TCFPSFRVVGEKQLPQEIIFLVWSPKRDLIALANTAGEVLLHRLASFHRVWSFPPNENTGKEVTCLAWRPDGKLLAFALADTKKIVLCDVEKPESLHSFSVEAPVSCMHWMEVTVESSVLTSFYEDESNLLLPKLPTLPKNYSNTSKIFSEENSDEIIKLLGDVRLNILVLGGSSGFIELYAYGMFKIARVTGIAGTCLALCLSSDLKSLSVVTEVSTNGASEVSYFQLETNLLYSFLPEVTRMARKFTHISALLQYINLSLTCMCEAWEEILMQMDSRLTKFVQEKNTTTSVQDEFMHLLLWGK
A
S
A
E
L
Q
T
L
L
M
N
Q
L
-
T
V
K
G
L
K
K
L
G
Q
S
I
E
S
S
Y
S
S
I
Q
K
-----
L
V
I
S
H
L
Q
S
G
S
E
S
L
L
Y
H
L
S
E
L
K
G
M
A
S
W
K
Q
K
Y
E
P
L
G
L
D
A
A
G
I
E
E
A
I
T
A
V
G
S
F
I
L
K
A
N
E
L
L
Q
V
I
D
---
S
S
-
M
K
N
F
K
A
F
F
R
W
L
Y
V
A
-----
M
L
R
M
T
D
K
M
T
Q
K
D
I
----
T
F
-
V
A
E
F
--
L
T
E
H
F
N
F
N
V
E
R
V
G
Q
Y
L
K
D
E
D
D
DLVSPPNTEGNQWYDFLQNSSHLKESPLLFPYYPRKSLHFVKRRMENIIDQCLQKPADVIGKSMNQAICIPLYRDTRSEDSTRRLFKFPFLWNNKTSNLHYLLFTILEDSLYKMCILRRHTDISQSVSNGLIAIKFGSFTYATTEKVRRSIYSCLDAQFYDDETVTVVLKDTVGREGRDRLLVQLPLSLVYNSEDSAEYQFTGTYSTRLDEQCSAIPTRTMHFEKHWRLLESMKAQYVAGNGFRKVSCVLSSNLRHVRVFEMDIDDEWELDES
20
PsiBlast_PDB
76.39
24%
30
* C10 *
4KMU
-
RPOC_ECOLI
D:
[1147-1233]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
R
P
K
E
P
A
I
L
A
E
I
S
G
I
V
S
F
G
K
E
T
K
G
K
R
R
L
V
I
T
P
V
D
G
S
D
P
Y
E
E
M
I
P
K
W
R
Q
L
N
V
F
-
E
G
E
R
V
E
R
G
D
V
I
S
D
G
-----
P
E
A
P
H
D
I
L
R
L
R
G
V
----
H
A
-
V
T
R
Y
--
I
V
N
E
V
Q
D
V
Y
R
L
Q
G
V
K
I
N
D
K
H
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
76.02
24%
30
- C10 -
4JK2
-
RPOC_ECOLI
D:
[1147-1233]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
R
P
K
E
P
A
I
L
A
E
I
S
G
I
V
S
F
G
K
E
T
K
G
K
R
R
L
V
I
T
P
V
D
G
S
D
P
Y
E
E
M
I
P
K
W
R
Q
L
N
V
F
-
E
G
E
R
V
E
R
G
D
V
I
S
D
G
-----
P
E
A
P
H
D
I
L
R
L
R
G
V
----
H
A
-
V
T
R
Y
--
I
V
N
E
V
Q
D
V
Y
R
L
Q
G
V
K
I
N
D
K
H
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
75.23
24%
31
- C10 -
4JK1
-
RPOC_ECOLI
D:
[1147-1233]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
R
P
K
E
P
A
I
L
A
E
I
S
G
I
V
S
F
G
K
E
T
K
G
K
R
R
L
V
I
T
P
V
D
G
S
D
P
Y
E
E
M
I
P
K
W
R
Q
L
N
V
F
-
E
G
E
R
V
E
R
G
D
V
I
S
D
G
-----
P
E
A
P
H
D
I
L
R
L
R
G
V
----
H
A
-
V
T
R
Y
--
I
V
N
E
V
Q
D
V
Y
R
L
Q
G
V
K
I
N
D
K
H
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
72.79
14%
-5
- C8 -
2HFI
-
YPPE_BACSU
A:
[1-123]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
S
Q
T
L
L
E
M
T
E
Q
-
M
I
E
V
A
E
K
G
A
D
R
Y
Q
E
G
-----------------
K
N
S
N
H
S
Y
D
F
F
E
T
I
K
P
A
V
E
E
N
D
E
L
A
A
R
W
A
E
G
A
L
E
L
I
K
V
R
R
P
K
Y
V
H
K
E
Q
I
E
A
V
K
D
N
F
L
---
E
L
-
V
L
Q
S
Y
V
H
------------------
H
I
H
K
K
R
F
----
K
D
-
I
T
E
S
--
V
L
Y
T
L
H
A
V
K
D
E
I
A
R
E
D
S
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
69.66
18%
13
- C7 -
1D2Z
1
TUBE_DROME
B:
[1-150]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
S
K
Y
S
R
N
T
E
L
R
R
V
E
D
N
D
I
Y
R
L
A
K
I
L
D
E
N
-
S
C
W
R
K
L
M
S
I
I
P
K
G
M
D
V
Q
A
C
S
G
A
G
C
L
N
F
P
A
E
I
K
K
G
F
K
Y
-
T
A
Q
D
V
F
Q
I
D
E
A
A
N
R
L
P
P
D
Q
----
S
K
S
Q
M
M
I
D
E
W
K
---
T
---
S
G
K
L
N
E
R
P
T
V
G
V
L
-----
L
Q
L
L
V
Q
A
E
L
F
S
A
A
----
D
F
-
V
A
L
D
--
F
L
N
E
S
T
P
A
R
P
V
D
G
P
G
A
L
I
S
L
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
66.72
11%
-8
* C7 *
4J1V
3
MOB1A_HUMAN
A:
[9-180]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRQAVM
L
P
E
G
E
D
L
N
E
W
I
A
V
-
N
T
V
D
F
F
N
Q
I
N
M
L
Y
G
T
I
T
E
F
C
T
E
A
S
C
P
V
M
S
A
G
P
R
Y
E
Y
H
W
A
D
---
P
I
K
C
S
A
P
K
Y
I
D
Y
L
M
T
W
V
Q
D
Q
L
D
D
E
T
L
F
P
S
K
I
G
V
P
F
P
K
N
-
F
M
S
V
A
K
---
T
I
-
L
K
R
L
F
R
V
Y
A
H
I
Y
H
Q
H
F
D
S
V
M
Q
L
Q
E
E
A
H
L
N
T
S
F
----
K
H
-
F
I
F
F
--
V
Q
E
F
N
L
I
D
R
R
E
L
A
P
L
Q
E
L
I
E
K
L
G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
64.92
24%
22
- C10 -
3LU0
-
RPOC_ECOLI
D:
[1147-1233]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
R
P
K
E
P
A
I
L
A
E
I
S
G
I
V
S
F
G
K
E
T
K
G
K
R
R
L
V
I
T
P
V
D
G
S
D
P
Y
E
E
M
I
P
K
W
R
QLN
V
F
-
E
G
E
R
V
E
R
G
D
V
I
S
D
G
-----
P
E
A
P
H
D
I
L
R
L
R
G
V
----
H
A
-
V
T
R
Y
--
I
V
N
E
V
Q
D
V
Y
R
L
Q
G
V
K
I
N
D
K
H
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
61.22
16%
-18
- C6 -
4WID
1
?
A:
[10-362]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDMAL
Q
H
A
V
D
L
L
E
K
M
L
A
D
E
E
KLTEFNLGDPLFESAND
D
P
I
K
T
L
E
E
I
I
Q
E
GDD
V
V
G
A
H
Q
L
V
V
T
Q
I
K
L
R
V
Q
R
N
R
R
L
A
D
E
I
I
R
E
Q
L
T
D
I
R
K
V
-
F
S
D
K
F
E
K
L
E
Q
G
I
Q
N
S
Y
L
L
L
D
K
L
K
T
P
F
Q
D
M
R
C
L
F
E
V
A
N
E
Q
F
N
D
T
P
V
P
P
Q
Y
K
E
F
M
V
C
L
K
Q
I
V
Q
Y
A
V
N
S
S
S
L
--
E
K
F
V
M
L
I
T
K
K
D
D
I
K
D
R
V
---
T
Y
T
C
M
K
Y
L
L
M
A
M
Q
G
T
G
G
-----
P
K
A
I
N
N
E
E
H
A
K
L
F
----
F
Q
-
L
S
N
Y
DD
L
T
D
A
N
H
D
G
L
E
L
I
K
K
L
D
K
E
Q
K
E
V
A
F
H
V
N
N
F
T
H
L
V
T
T
L
G
M
A
L
Y
K
E
G
H
Q
K
N
D
E
A
M
L
G
M
H
T
P
I
T
M
L
S
D
Q
V
R
V
L
I
L
Y
L
I
D
E
I
V
H
A
I
H
T
NSNQS
N
D
E
L
I
D
G
L
K
P
K
V
R
I
V
I
N
E
F
H
A
T
L
M
M
GIDK
M
K
F
Y
S
L
N
E
L
R
E
I
V
N
D
K
I----------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
58.47
15%
4
- C8 -
3IYN
-
CAP9_ADE05
Q:
[7-134]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
S
I
V
S
S
Y
L
T
T
R
M
P
P
W
A
G
V
R
Q
N
V
M
G
S
S
I
D
G
R
P
V
L
P
A
N
S
T
T
L
T
Y
E
T
V
S
G
T
P
L
E
T
A
A
--------
S
A
A
A
S
A
A
A
A
T
A
R
G
---
I
V
-
T
D
F
A
F
L
S
P
L
A
S
S
A
A
-----
S
R
S
S
A
R
D
D
K
L
T
A
L
----
L
A
-
Q
L
D
S
--
L
T
R
E
L
N
V
V
S
Q
Q
L
L
D
L
R
Q
Q
V
S
A
LKAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
57.20
13%
1
- C7 -
4D9O
-
VP24_EBORE
A:
[10-231]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVP
P
K
K
D
M
E
K
G
V
I
F
S
D
-
L
C
N
F
L
I
T
Q
T
L
---
Q
G
W
K
V
Y
W
A
G
I
E
F
D
V
S
Q
K
G
M
A
L
L
T
R
L
K
T
A
M
T
R
N
L
F
P
H
L
F
Q
N
P
N
S
-
V
I
Q
S
P
I
W
A
L
R
V
I
L
A
A
G
L
Q
D
Q
L
L
D
H
S
L
V
E
P
L
T
---
G
A
-
L
G
L
I
S
D
W
L
L
T
T
T
S
T
-----
H
F
N
L
R
T
R
S
V
K
D
Q
L
----
S
L
R
M
L
S
L
--
I
R
S
N
I
L
Q
F
I
N
K
L
D
A
L
H
V
V
N
Y
N
GLLS
S
I
E
I
G
T
ST
H
T
I
I
I
T
R
T
NM
G
F
L
V
E
V
Q
EV
K
F
S
L
L
H
ESAFKPFT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
57.12
30%
-40
- C9 -
3S4U
-
?
A:
[258-298]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
L
A
L
F
K
E
-----
M
Q
S
V
K
D
N
K
G
L
N
E
Q
----
D
K
-
L
A
K
-------
T
T
A
I
Q
A
Q
L
D
D
L
D
R
L
N
N
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
53.85
30%
-22
- C9 -
3P7I
1
?
A:
[267-307]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
L
A
L
F
K
E
-----
M
Q
S
V
K
D
N
K
G
L
N
E
Q
----
D
K
-
L
A
K
-------
T
T
A
I
Q
A
Q
L
D
D
L
D
R
L
N
N
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
53.57
24%
40
- C10 -
3IYD
-
RPOC_ECOLI
D:
[1147-1233]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
R
P
K
E
P
A
I
L
A
E
I
S
G
I
V
S
F
G
K
E
T
K
G
K
R
R
L
V
I
T
P
V
D
G
S
D
P
Y
E
E
M
I
P
K
W
R
Q
L
N
V
F
-
E
G
E
R
V
E
R
G
D
V
I
S
D
G
-----
P
E
A
P
H
D
I
L
R
L
R
G
V
----
H
A
-
V
T
R
Y
--
I
V
N
E
V
Q
D
V
Y
R
L
Q
G
V
K
I
N
D
K
H
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
53.11
42%
-25
- C9 -
2QIZ
-
UFD2_YEAST
A:
[437-471]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
I
E
K
V
K
K
I
AANH
D
V
-
F
A
R
F
--
I
T
A
Q
L
S
K
M
E
K
A
L
K
T
T
E
S
L
R
F
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
51.45
42%
-22
- C9 -
3M63
-
DSK2_YEAST (first)
A:
[423-457]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
I
E
K
V
K
K
I
AANH
D
V
-
F
A
R
F
--
I
T
A
Q
L
S
K
M
E
K
A
L
K
T
T
E
S
L
R
F
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
50.49
28%
54
- C9 -
4CQD
-
ATZC_PSESD
A:
[131-176]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
M
Q
V
L
H
G
T
L
Y
T
R
T
H
V
D
V
D
S
V
A
K
T
K
A
V
E
A
V
L
E
A
K
E
E
L
K
D
L
I
D
I
Q
V
V
A
F
A
Q
S
G
F
F
V
D
L
E
S
---
E
S
-
L
I
R
K
S
L
D
M
G
C
D
L
V
G
-----
G
V
D
P
A
T
R
E
N
N
V
E
G
----
S
L
-
D
L
C
F
--
K
L
A
K
E
Y
D
V
D
I
D
Y
H
I
H
D
I
G
T
V
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
50.11
28%
55
- C9 -
2QT3
-
ATZC_PSESD
A:
[111-156]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
M
Q
V
L
H
G
T
L
Y
T
R
T
H
V
D
V
D
S
V
A
K
T
K
A
V
E
A
V
L
E
A
K
E
E
L
K
D
L
I
D
I
Q
V
V
A
F
A
Q
S
G
F
F
V
D
L
E
S
---
E
S
-
L
I
R
K
S
L
D
M
G
C
D
L
V
G
-----
G
V
D
P
A
T
R
E
N
N
V
E
G
----
S
L
-
D
L
C
F
--
K
L
A
K
E
Y
D
V
D
I
D
Y
H
I
H
D
I
G
T
V
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
50.04
28%
53
- C9 -
4CQC
-
ATZC_PSESD
A:
[131-176]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
M
Q
V
L
H
G
T
L
Y
T
R
T
H
V
D
V
D
S
V
A
K
T
K
A
V
E
A
V
L
E
A
K
E
E
L
K
D
L
I
D
I
Q
V
V
A
F
A
Q
S
G
F
F
V
D
L
E
S
---
E
S
-
L
I
R
K
S
L
D
M
G
C
D
L
V
G
-----
G
V
D
P
A
T
R
E
N
N
V
E
G
----
S
L
-
D
L
C
F
--
K
L
A
K
E
Y
D
V
D
I
D
Y
H
I
A
D
I
G
T
V
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
49.71
28%
55
- C9 -
4CQB
-
ATZC_PSESD
A:
[131-176]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
M
Q
V
L
H
G
T
L
Y
T
R
T
H
V
D
V
D
S
V
A
K
T
K
A
V
E
A
V
L
E
A
K
E
E
L
K
D
L
I
D
I
Q
V
V
A
F
A
Q
S
G
F
F
V
D
L
E
S
---
E
S
-
L
I
R
K
S
L
D
M
G
C
D
L
V
G
-----
G
V
D
P
A
T
R
E
N
N
V
E
G
----
S
L
-
D
L
C
F
--
K
L
A
K
E
Y
D
V
D
I
D
Y
H
I
H
D
I
G
T
V
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------