@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0755: (2015-12-18 )
MLKNDDFVIAKNQLGNIVPNSVGVIRAVNGKSAMVLFIGLNELKRVDFSELEAIDIYRTGKGYDKKICNICHILKNTDGFEINQTDAKGRKTTRPSCRECRKNIDGVKLSSTEKKKMDEIAPPKGSVFTCPICEKRSIVGVTANLVHDHNHDTGWGREWICDSCNTGLGRFKDNPKFLEKVIEYLKKYEK
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------.........10..-.--.....20........30-.----.......40......----..50........60........70......--..-80.....-...90........100.......---110.......120...--....130.......140.......150.-----.....-.160...-....170.---.-------------.....180-......-..190------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------MLKND
D
F
V
I
A
K
N
Q-L--GNIVPNSV
G
V
I
R
AVNGK-
S
----
A
M
V
L
F
I
G
L
N
E
L
KRV
D
----
F
S
E
L
E
A
I
D
I
Y
RTGKGY
D
K
K
I
C
N
I
C
H
I
LKNT--DG-
F
E
INQTD-AKGRKTTR
P
S
C
R
E
C
R
KNID
G
V
KL---S
S
T
E
K
K
K
M
D
EIAPPKG--
S
V
F
TCPICEKR
S
I
V
G
V
T
A
N
L
VHDHNHDT-----GWGRE-WICDSCN-TGLGRFKD---
N
-------------
P
K
F
L
E
K
V
--
I
E
Y
L
K
K
-YEK--------------------------------------------------------------------------------------
16
PsiBlast_CBE
96.62
100%
-85
- C11 -
3FC3
6
?
B:
[12-199]
----------------------------------------------------------------------------------------------------------------
L
K
N
D
D
F
V
I
A
K
N
Q
-
L
--
G
N
I
V
P
N
S
V
G
V
I
R
A
V
N
G
K
-
S
----
A
M
V
L
F
I
G
L
N
E
L
K
R
V
D
----
F
S
E
L
E
A
I
D
I
Y
R
T
G
K
G
Y
D
K
K
I
C
N
I
C
H
I
L
K
N
T
--
D
G
-
F
E
I
N
Q
T
D
-
A
K
G
R
K
T
T
R
P
S
C
R
E
C
R
K
N
I
D
G
V
K
L
---
S
S
T
E
K
K
K
M
D
E
I
A
P
P
K
G
--
S
V
F
T
C
P
I
C
E
K
R
S
I
V
G
V
T
A
N
L
V
H
D
H
N
H
D
T
-----
G
W
G
R
E
-
W
I
C
D
S
C
N
-
T
G
L
G
R
F
K
D
---
N
-------------
P
K
F
L
E
K
V
--
I
E
Y
L
K
K
-
Y
E
---------------------------------------------------------------------------------------
15
PsiBlast_CBE
95.81
100%
-84
- C11 -
3GOX
6
?
B:
[11-199]
---------------------------------------------------------------------------------------------------------------
M
L
K
N
D
D
F
V
I
A
K
N
Q
-
L
--
G
N
I
V
P
N
S
V
G
V
I
R
A
V
N
G
K
-
S
----
A
M
V
L
F
I
G
L
N
E
L
K
R
V
D
----
F
S
E
L
E
A
I
D
I
Y
R
T
G
K
G
Y
D
K
K
I
C
N
I
C
H
I
L
K
N
T
--
D
G
-
F
E
I
N
Q
T
D
-
A
K
G
R
K
T
T
R
P
S
C
R
E
C
R
K
N
I
D
G
V
K
L
---
S
S
T
E
K
K
K
M
D
E
I
A
P
P
K
G
--
S
V
F
T
C
P
I
C
E
K
R
S
I
V
G
V
T
A
N
L
V
H
D
H
N
H
D
T
-----
G
W
G
R
E
-
W
I
C
D
S
C
N
-
T
G
L
G
R
F
K
D
---
N
-------------
P
K
F
L
E
K
V
--
I
E
Y
L
K
K
-
Y
E
---------------------------------------------------------------------------------------
43
Fugue
95.77
100%
-85
- C11 -
3FC3
6
?
A:
[11-199]
---------------------------------------------------------------------------------------------------------------
M
L
K
N
D
D
F
V
I
A
K
N
Q
-
L
--
G
N
I
V
P
N
S
V
G
V
I
R
A
V
N
G
K
-
S
----
A
M
V
L
F
I
G
L
N
E
L
K
R
V
D
----
F
S
E
L
E
A
I
D
I
Y
R
T
G
K
G
Y
D
K
K
I
C
N
I
C
H
I
L
K
N
T
--
D
G
-
F
E
I
N
Q
T
D
-
A
K
G
R
K
T
T
R
P
S
C
R
E
C
R
K
N
I
D
G
V
K
L
---
S
S
T
E
K
K
K
M
D
E
I
A
P
P
K
G
--
S
V
F
T
C
P
I
C
E
K
R
S
I
V
G
V
T
A
N
L
V
H
D
H
N
H
D
T
-----
G
W
G
R
E
-
W
I
C
D
S
C
N
-
T
G
L
G
R
F
K
D
---
N
-------------
P
K
F
L
E
K
V
--
I
E
Y
L
K
K
-
Y
E
---------------------------------------------------------------------------------------
1
PsiBlast_PDB
95.48
100%
-85
- C11 -
3FC3
6
?
A:
[11-199]
---------------------------------------------------------------------------------------------------------------
M
L
K
N
D
D
F
V
I
A
K
N
Q
-
L
--
G
N
I
V
P
N
S
V
G
V
I
R
A
V
N
G
K
-
S
----
A
M
V
L
F
I
G
L
N
E
L
K
R
V
D
----
F
S
E
L
E
A
I
D
I
Y
R
T
G
K
G
Y
D
K
K
I
C
N
I
C
H
I
L
K
N
T
--
D
G
-
F
E
I
N
Q
T
D
-
A
K
G
R
K
T
T
R
P
S
C
R
E
C
R
K
N
I
D
G
V
K
L
---
S
S
T
E
K
K
K
M
D
E
I
A
P
P
K
G
--
S
V
F
T
C
P
I
C
E
K
R
S
I
V
G
V
T
A
N
L
V
H
D
H
N
H
D
T
-----
G
W
G
R
E
-
W
I
C
D
S
C
N
-
T
G
L
G
R
F
K
D
---
N
-------------
P
K
F
L
E
K
V
--
I
E
Y
L
K
K
-
Y
E
---------------------------------------------------------------------------------------
17
HHSearch
95.19
100%
-86
- C11 -
3GOX
6
?
A:
[11-199]
---------------------------------------------------------------------------------------------------------------
M
L
K
N
D
D
F
V
I
A
K
N
Q
-
L
--
G
N
I
V
P
N
S
V
G
V
I
R
A
V
N
G
K
-
S
----
A
M
V
L
F
I
G
L
N
E
L
K
R
V
D
----
F
S
E
L
E
A
I
D
I
Y
R
T
G
K
G
Y
D
K
K
I
C
N
I
C
H
I
L
K
N
T
--
D
G
-
F
E
I
N
Q
T
D
-
A
K
G
R
K
T
T
R
P
S
C
R
E
C
R
K
N
I
D
G
V
K
L
---
S
S
T
E
K
K
K
M
D
E
I
A
P
P
K
G
--
S
V
F
T
C
P
I
C
E
K
R
S
I
V
G
V
T
A
N
L
V
H
D
H
N
H
D
T
-----
G
W
G
R
E
-
W
I
C
D
S
C
N
-
T
G
L
G
R
F
K
D
---
N
-------------
P
K
F
L
E
K
V
--
I
E
Y
L
K
K
-
Y
E
---------------------------------------------------------------------------------------
2
PsiBlast_PDB
95.19
100%
-86
- C11 -
3GOX
6
?
A:
[11-199]
---------------------------------------------------------------------------------------------------------------
M
L
K
N
D
D
F
V
I
A
K
N
Q
-
L
--
G
N
I
V
P
N
S
V
G
V
I
R
A
V
N
G
K
-
S
----
A
M
V
L
F
I
G
L
N
E
L
K
R
V
D
----
F
S
E
L
E
A
I
D
I
Y
R
T
G
K
G
Y
D
K
K
I
C
N
I
C
H
I
L
K
N
T
--
D
G
-
F
E
I
N
Q
T
D
-
A
K
G
R
K
T
T
R
P
S
C
R
E
C
R
K
N
I
D
G
V
K
L
---
S
S
T
E
K
K
K
M
D
E
I
A
P
P
K
G
--
S
V
F
T
C
P
I
C
E
K
R
S
I
V
G
V
T
A
N
L
V
H
D
H
N
H
D
T
-----
G
W
G
R
E
-
W
I
C
D
S
C
N
-
T
G
L
G
R
F
K
D
---
N
-------------
P
K
F
L
E
K
V
--
I
E
Y
L
K
K
-
Y
E
---------------------------------------------------------------------------------------
48
Fugue
51.45
24%
-59
* C10 *
1Y88
10
Y1548_ARCFU
A:
[16-199]
----------------------------------------------------------------------------------------------------NL
Y
F
Q
G
H
M
V
A
R
L
L
E
E
H
G
F
E
T
K
T
N
V
-
I
VQ
G
N
C
V
E
Q
E
I
D
V
V
A
E
R
D
G
E
-
R
----
Y
M
I
E
C
K
F
H
N
--
I
P
V
Y
----
T
G
L
K
E
A
M
Y
T
Y
A
R
F
L
D
V
E
K
H
G
F
T
Q
P
W
I
F
T
N
T
---------
K
F
S
-
E
E
A
K
K
Y
A
G
C
V
---------
G
I
K
L
T
G
W
S
Y
P
E
K
E
G
I
E
V
L
L
E
S
K
G
LY
P
I
T
I
L
R
I
D
K
E
V
L
D
E
L
V
R
A
G
L
V
------------------
F
C
R
D
V
V
S
-
A
G
E
E
K
L
R
E
I
GL
S
-------------
A
K
K
A
R
E
V
--
I
A
E
A
K
K
-
V
I
G
G
S------------------------------------------------------------------------------------
35
HHSearch
44.28
13%
-80
- C11 -
2JNY
-
?
A:
[8-53]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
--
E
V
L
A
C
P
K
D
K
G
P
L
R
Y
------
L
E
-----------
S
E
Q
-
L
-
L
V
N
E
R
L
N
-
L
A
Y
R
I
D
D
G
---
I
-------------
P
V
L
L
I
D
E
--
A
T
E
W
T
P
-
N
N
L
--------------------------------------------------------------------------------------
8
PsiBlast_PDB
44.26
23%
-10
- C9 -
3JRO
-
A:
[1301-1414]
-----------------------------------------------------------------------------------------------------------------------------
L
--
N
D
V
V
R
A
S
K
L
A
I
E
S
K
N
G
H
L
S
----
V
L
I
S
Y
L
G
S
N
D
P
R
I
R
D
----
L
A
E
L
Q
L
Q
K
W
S
T
G
G
C
S
I
D
K
N
I
S
K
I
Y
K
L
L
S
G
S
PF
E
G
L
F
S
L
K
E
L
E
-
S
E
F
S
W
L
C
L
L
N
L
T
L
C
Y
G
Q
I
D
E
Y
S
L
---
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
Y
D
--
D
P
I
G
V
I
F
Q
L
Y
A
A
N
E
N
T
E
K
L
Y
K
E
V
R
Q
R
T
N
-----
A
L
D
V
Q
-
F
C
W
Y
L
I
Q
-
T
L
R
F
N
G
T
R
---
V
-------------
F
S
K
E
T
S
D
--
E
A
T
F
A
F
-
A
A
Q
--------------------------------------------------------------------------------------
31
HHSearch
43.85
20%
-77
- C11 -
2HF1
1
Y3345_CHRVO
A:
[6-54]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
--
E
I
L
V
C
P
L
C
K
G
P
L
V
F
D
-----------
K
------
S
K
D
-
E
-
L
I
C
K
G
D
R
-
L
A
F
P
I
K
D
G
---
I
-------------
P
M
M
L
E
S
E
--
A
R
E
L
A
P
-
E
E
E
--------------------------------------------------------------------------------------
30
HHSearch
43.43
16%
-104
- C11 -
2JR6
-
Y874_NEIMA
A:
[6-55]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
--
D
I
L
V
C
P
V
T
K
G
R
L
E
Y
------
H
Q
-----------
D
K
Q
-
E
-
L
W
S
R
Q
A
K
-
L
A
Y
P
I
K
D
G
---
I
-------------
P
Y
M
L
E
N
E
--
A
R
P
L
S
E
-
E
E
L
--------------------------------------------------------------------------------------
52
Fugue
43.06
13%
-11
- C10 -
2EW0
2
Y353_ACIAD
A:
[5-179]
----------------------------------------------------------------------------------------------------------------
Y
L
T
H
R
C
L
I
A
P
P
E
M
A
--
D
D
F
F
A
N
T
V
I
Y
L
A
R
H
D
E
E
-
G
----
A
Q
G
I
I
I
--
N
R
P
A
G
I
Q
----
I
K
E
L
L
N
D
L
D
I
D
A
D
N
V
N
P
H
E
V
L
Q
-----------
G
-
G
P
L
R
P
E
A
-
G
F
V
L
H
T
G
Q
P
T
W
H
S
S
I
A
V
G
E
N
V
C
I
---
T
T
S
-
K
D
I
L
D
A
I
A
H
N
E
G
--
V
-------
G
R
Y
Q
I
A
L
G
Y
A
S
W
G
K
N
Q
L
E
D
E
-----
I
A
R
G
D
-
W
L
I
C
D
A
D
M
D
L
I
--
F
N
L
---
P
-------------
Y
D
D
R
W
D
A
--
A
Y
K
K
I
G
-
V
D
R
TWLAS---------------------------------------------------------------------------------
4
PsiBlast_PDB
41.33
23%
-13
- C9 -
3BG1
-
NU145_YEAST
B:
[300-413]
-----------------------------------------------------------------------------------------------------------------------------
L
--
N
D
V
V
R
A
S
K
L
A
I
E
S
K
N
G
H
L
S
----
V
L
I
S
Y
L
G
S
N
D
P
R
I
R
D
----
L
A
E
L
Q
L
Q
K
W
S
T
G
G
C
S
I
D
K
N
I
S
K
I
Y
K
L
L
S
G
S
PF
E
G
L
F
S
L
K
E
L
E
-
S
E
F
S
W
L
C
L
L
N
L
T
L
C
Y
G
Q
I
D
E
Y
S
L
---
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
41.02
23%
-7
- C9 -
4XMM
-
B:
[241-354]
-----------------------------------------------------------------------------------------------------------------------------
L
--
N
D
V
V
R
A
S
K
L
A
I
E
S
K
N
G
H
L
S
----
V
L
I
S
Y
L
G
S
N
D
P
R
I
R
D
----
L
A
E
L
Q
L
Q
K
W
S
T
G
G
C
S
I
D
K
N
I
S
K
I
Y
K
L
L
S
G
S
PF
E
G
L
F
S
L
K
E
L
E
-
S
E
F
S
W
L
C
L
L
N
L
T
L
C
Y
G
Q
I
D
E
Y
S
L
---
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
Y
D
--
D
P
I
G
V
I
F
Q
L
Y
A
A
N
E
N
T
E
K
L
Y
K
E
V
R
Q
R
T
N
-----
A
L
D
V
Q
-
F
C
W
Y
L
I
Q
-
T
L
R
F
N
G
T
R
---
V
-------------
F
S
K
E
T
S
D
--
E
A
T
F
A
F
-
A
A
Q
--------------------------------------------------------------------------------------
3
PsiBlast_PDB
40.17
23%
-11
- C9 -
3BG0
-
NU145_YEAST
B:
[300-413]
-----------------------------------------------------------------------------------------------------------------------------
L
--
N
D
V
V
R
A
S
K
L
A
I
E
S
K
N
G
H
L
S
----
V
L
I
S
Y
L
G
S
N
D
P
R
I
R
D
----
L
A
E
L
Q
L
Q
K
W
S
T
G
G
C
S
I
D
K
N
I
S
K
I
Y
K
L
L
S
G
S
PF
E
G
L
F
S
L
K
E
L
E
-
S
E
F
S
W
L
C
L
L
N
L
T
L
C
Y
G
Q
I
D
E
Y
S
L
---
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
39.95
29%
-29
- C11 -
1E7L
6
END7_BPT4
A:
[6-98]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
---
Y
K
E
E
K
Q
K
F
Y
-----
D
A
--
Q
N
G
K
C
L
I
C
Q
R
E
L
N
P
D
-
V
Q
A
N
H
L
D
H
D
H
E
L
NGPKA
G
K
V
R
G
-
L
L
C
N
L
C
D
-
A
A
E
G
Q
M
K
H
---
K
F
N
R
SGLKGQGVD
Y
L
E
W
L
E
N
L
--
L
T
Y
L
K
S
-
D
Y
T
--------------------------------------------------------------------------------------
5
PsiBlast_PDB
39.31
23%
-7
- C9 -
3IKO
-
NU145_YEAST
B:
[300-413]
-----------------------------------------------------------------------------------------------------------------------------
L
--
N
D
V
V
R
A
S
K
L
A
I
E
S
K
N
G
H
L
S
----
V
L
I
S
Y
L
G
S
N
D
P
R
I
R
D
----
L
A
E
L
Q
L
Q
K
W
S
T
G
G
C
S
I
D
K
N
I
S
K
I
Y
K
L
L
S
G
S
PF
E
G
L
F
S
L
K
E
L
E
-
S
E
F
S
W
L
C
L
L
N
L
T
L
C
Y
G
Q
I
D
E
Y
S
L
---
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
38.95
19%
-76
- C11 -
1QP2
-
PSAE_NOSS8
A:
[1-69]
---------------------------------------------------------------------------------------------------------------
M
V
Q
R
G
S
K
V
R
I
L
R
P
----
E
S
Y
W
F
Q
D
V
G
T
V
A
S
V
D
Q
S
-
G
IKYP
V
I
V
R
F
E
K
V
N
Y
S
G
I
N
T
N
N
F
A
E
D
E
L
V
E
V
E
A
P
K
A
K
P
K
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
38.70
20%
-43
- C11 -
2JS4
-
Y2007_BORBR
A:
[7-55]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
L
V
C
P
V
C
K
G
R
L
E
F
Q
------
R
-----------
A
Q
A
-
E
-
L
V
C
N
A
D
R
-
L
A
F
P
V
R
D
G
---
V
-------------
P
I
M
L
E
A
E
--
A
R
S
L
D
A
-
E
A
P
--------------------------------------------------------------------------------------
45
Fugue
37.67
14%
-18
- C5 -
1XIP
-
NU159_YEAST
A:
[1-381]
A
S
S
L
K
D
E
V
P
T
E
TSED
F
G
F
K
FLGQKQILPSFNEKLPFASLQN
L
D
I
S
NSKS
L
F
V
A
A
S
GS
K
A
V
V
G
E
L
Q
L
L
R
D
H
I
T
S
DS
T
P
L
T
F
K
W
E
K
E
I
P
DVI
F
V
C
F
H
GD
Q
V
L
V
S
T
RN
A
L
Y
S
L
D
L
E
E
L
S
E
F
R
T
V
T
S
F
--------
E
K
P
V
F
Q
L
K
N
V
N
---
N
----
T
L
V
I
L
N
S
V
N
D
L
S
A
L
D
----
L
R
T
K
S
T
K
Q
L
A
Q
N
V
T
S
F
D
V
T
N
S
Q
L
A
V
L
L
K
D
R
S
F
Q
S
-
F
A
W
R
N
G
E
M
E
K
Q
F
E
F
S
L
P
----------------------
S
E
L
E
E
L
P
V
E
E
Y
--
S
P
L
S
V
T
I
L
S
P
Q
D
F
L
A
V
F
G
N
V
I
S
E
T
D
D
E
V
-----
S
Y
D
Q
K
M
Y
I
I
K
H
I
D
--
G
S
A
S
F
Q
E
---
T
-------------
F
D
I
T
P
P
F
GQ
I
V
R
F
P
Y
M
Y
K
V
T
L
S
GLIEPD
A
N
V
N
V
L
A
S
SCSS
E
V
S
I
W
DSK
Q
V
I
E
P
SQDSE
R
A
V
L
P
I
S
EETD
K
D
T
N
P
I
G
V
A
V
D
VVTSGL
P
L
V
Y
I
L
N
NEG
S
L
Q
I
V
G
L
F
H