@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0066: (2016-03-12 )
MKEVNYREDDWREAKSALAPFAAANWVGGLFNNLEKVSKNMEEAEEDVQELDSDHAISFQHTNYRGKYSAIEDDLMVLYKFSCHAGEKMETLVDQPFYEKLDAFVDGMQDLSISTYSTTNRIGAKSKQTYTTTSGGSQVIESIKEGATIEDLMNGDNFYANQMQLQYRDWQRANPDQDVSKKDFQMGMLHSRAFEYKSIKDEQQEKEFWVNIVATVVIVGVSIFCPPAGLALAVGYGSLEAGSAISGKDWVSGRELSTEERALRGGLALLDIVPGVKALSTGAKAASAGSKLVRVGDNVLAGSKNVGKGTIDNGIQAGKQAMDLRLANAKKVSEAVQKKLTKDLDDIGTMAKTIQNKTKETFTLPPREQLAFARGGSIPEQSATGAAAIAAKKKLKDIMQNMDNLNVKGGGKDDIIEQNKSLKFTSLEESEKWGIDGFSVWRNSLSSREIQAIRDYTDIWHYGNMNGYLRGSVEKLAPDNAERIKNLSSALEKAELPDNIILYRGTSSEILDNFLDLKNLNYQNLVGKTIEEKGFMSTTTISNQTFSGNVTMKINAPKGSKGAYLAHFSETPEEAEVLFNIGQKMLIKEVTELNGKIEIIVDLL
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.....-----..260.......270.......280..--.....290.......300.......310.......320.......330.......340...----------....350.......360...--------....370.......380.......390.......400.......410.......420....-..--..430.......440.......450.......460.......--470---------..-...---.---.--..480..----.....490.......500...----------....510....-------------.--------.--.520---------.---------.-------------.....----.530.......---540--..--...---..---550.......560------.....--..570.......580.......590--.-----.--.--..-..600..---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKEVNYR
E
D
D
W
R
E
A
K
S
ALA
P
F
A
A
A
N
W
V
G
G
L
F
N
N
L
E
K
V
S
K
N
M
E
E
A
E
E
D
V
Q
E
LDSD
H
A
I
S
F
QHTNYRGKYSAIED
D
L
M
V
L
Y
K
FSCHAG
E
K
M
E
T
L
VD
Q
P
F
Y
E
K
L
D
A
F
V
D
G
M
Q
DL
S
I
S
TYSTTNRIGAKSK
Q
T
Y
T
TTSG
G
S
Q
V
I
E
S
I
KEGA
T
I
E
D
L
MNGDNFYAN
Q
M
Q
L
Q
YRDWQRANPDQDV
S
K
K
D
F
Q
M
G
M
L
H
S
RAFEYKSIK
D
E
Q
Q
E
K
E
F
W
V
N
I
V
A
T
V
V
I
V
G
V
S
I
FCPPA
G
L
A
L
A
V
GYGSLEAGSAISGKDWVSGREL
S
-----
T
E
E
R
A
L
RGG
L
A
L
L
D
IVPG
V
K
A
L
STGAK--AASAGS
K
L
V
RVGDNVLAGSKNVGKGTI
D
N
G
I
Q
A
G
K
Q
A
M
D
LRLA
N
A
K
K
V
S
E
A
V
Q
K
K
L
T
K
D
L
D
----------
D
I
G
T
M
A
K
T
I
Q
NKTKETFTLP--------
P
R
E
Q
L
A
FARGGSIPEQSATG
A
A
A
I
A
A
K
K
K
L
K
D
I
M
Q
N
MDN
L
N
VKGGGK
D
D
I
I
EQNKS-LKFT-SL--EESEKWGI
D
G
F
S
V
W
R
NSLSS
R
E
I
Q
A
I
R
D
Y
T
D
I
WHYGNMN
G
Y
L
--R-----------G
S
-
V
E
K---L---A--PD
N
A
E
R
I
----
K
N
L
S
S
A
L
E
K
AELPD
N
I
I
L
YRG----------
T
S
S
E
I
L
D
N
F
L
D
-------------L--------K--NL
N
----------
Y
---------
Q
-------------
N
L
V
G
K
----
T
I
E
EKG
F
M
S
T
T
---
T
IS--N
Q
--
T
FS---G
N
---
V
T
M
K
I
NAPKGSK
G
------
A
Y
L
A
H--FSET
P
E
E
A
E
V
L
F
N
I
G
Q
K
M
L
I
K
E
V
T
E--L-----N--G--
K
I
-
E
I
I
V
DLL---
38
Fugue
83.34
17%
-16
- C3 -
3BUZ
1
?
A:
[1-413]
----------------------------
A
F
I
E
R
P
E
D
F
L
K
D
K
E
N
A
I
Q
W
E
K
K
E
A
E
R
V
E
K
N
L
D
T
L
E
K
E
A
L
E
L
Y
K
K
D
S
E
Q
I
S
N
Y
S
Q
T
R
Q
Y
F
Y
D
Y
Q
I
E
S
N
P
R
E
K
E
Y
K
N
L
R
N
A
I
S
K
N
K
I
D
--------------------
K
P
I
N
V
Y
Y
F
E
----------
S
P
E
K
F
A
F
N
K
E
I
R
T
E
N
Q
N
E
I
S
L
E
K
F
N
E
L
K
E
T
I
Q
D
K
L
F
K
Q
D
G
F
K
D
V
S
L
Y
E
P
G
N
G
D
E
K
P
T
P
L
L
I
H
L
K
L
P
K
------------------------------------------------------------------------------------------------------------------------------------------------
N
T
G
M
L
P
Y
I
N
S
N
D
V
K
T
L
I
E
--------
Q
D
Y
S
I
K
I
D
K
I
V
R
I
V
I
E
G
K
Q
Y
I
K
A
E
A
S
I
V
N
S
L
D
F
K
D
D
---------------------------
V
--
S
K
G
D
L
W
G
K
E
N
Y
S
D
W
S
N
K
L
T
P
N
E
L
A
D
V
N
D
Y
M
R
-
G
G
Y
T
A
I
N
N
Y
L
--
I
-----------
S
N
-
G
P
L
---
N
---
N
PN
P
E
L
D
S
K
V
----
N
N
I
E
N
A
L
K
L
T
P
I
P
S
N
L
I
V
Y
R
R
----------
S
G
P
Q
E
F
G
L
T
L
T
-------------
S
--------
P
--
E
Y
D
FNK
I
E
N
I
D
A
F
K
---------
E
-------------
K
W
E
G
K
----
V
I
T
Y
P
N
F
I
S
T
S
IGS
V
N
M
--
S
A
--
F
A
K
---
R
K
---
I
I
L
R
I
N
I
P
K
D
S
P
G
------
A
Y
L
S
A
--
I
P
G
Y
A
G
E
Y
E
V
L
L
N
H
G
S
K
F
K
I
N
K
V
D
S
--
Y
-----
K
DG
T
--
V
T
-
K
L
I
L
D
A
T
LIN
29
HHSearch
83.34
28%
-53
- C3 -
2WN4
-
?
A:
[217-419]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
L
D
F
K
D
D
V
--
S
K
G
D
S
W
G
K
A
N
Y
N
D
W
S
N
K
L
T
P
N
E
L
A
D
V
N
D
Y
M
R
-
G
G
Y
T
A
I
N
N
Y
L
--
I
-----------
S
N
-
G
P
V
NN-
P
---
N
--
P
E
L
D
S
K
I
----
T
N
I
E
N
A
L
K
R
E
P
I
P
T
N
L
T
V
Y
R
R
----------
S
G
P
Q
E
F
G
L
T
L
T
-------------
S
PEYDFNK
L
E
--
N
I
D
A
F
--------
K
---------
S
-------------
K
W
E
G
Q
----
A
L
S
Y
P
N
F
I
S
T
S
---
I
G
S
--
V
N
MS
A
F
A
K--
R
K
---
I
V
L
R
I
T
I
P
K
G
S
P
G
------
A
Y
L
S
A
--
I
P
G
Y
A
G
E
Y
E
V
L
L
N
H
G
S
K
F
K
I
N
K
I
D
S
Y
K
D
-----
G
--
T
I
T
K
L
-
I
V
D
A
T
L
I
---
36
Fugue
82.80
19%
-6
- C3 -
1QS1
-
?
A:
[60-461]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
K
V
E
D
F
K
E
D
K
E
K
A
K
E
W
G
K
E
K
E
K
E
W
KLT
A
T
E
K
G
K
M
N
N
F
L
D
N
K
N
D
I
K
T
N
Y
K
E
I
T
F
S
M
AG
S
F
E
D
E
I
K
D
L
K
E
I
D
K
M
F
D
K
T
N
L
S
N
S
I
I
T
Y
K
N
V
E
P
T
T
I
G
F
N
K
S
L
T
E
G
N
T
I
N
S
D
A
M
A
Q
F
K
E
Q
F
L
D
R
D
I
K
F
DSY
L
D
T
H
L
T
A
Q
Q
V
S
S
K
E
R
V
I
L
K
V
T
V
P
SGKGST
T
P
T
K
A
G
V
I
L
N
N
S
E
Y
K
M
L
I
D
N
G
Y
M
V
H
V
D
K
V
S
K
V
V
K
K
G
V
E
C
L
Q
I
E
G
T
L
K
K
S
L
-----
D
-
F
K
N
D
-
I
N
--
A
E
A
H
S
W
G
M
K
N
Y
E
E
W
A
K
D
L
T
D
S
Q
R
E
A
L
D
G
Y
A
R
-
Q
D
Y
K
E
I
N
N
Y
L
--
R
-----------
N
Q
-
G
G
S
---
G
---
N
--
E
K
L
D
A
Q
I
----
K
N
I
S
D
A
L
G
K
K
P
I
P
E
N
I
T
V
Y
R
W
----------
C
G
M
P
E
F
G
Y
Q
I
S
-------------
D
--------
P
--
L
P
S
----------
L
---------
K
-------------
D
F
E
E
Q
FLN
T
I
K
E
D
K
G
Y
M
S
T
S
---
L
S
S
--
E
R
--
L
A
A
FGS
R
K
---
I
I
L
R
L
Q
V
P
K
G
S
T
G
------
A
Y
L
S
A
--
I
G
G
F
A
S
E
K
E
I
L
L
D
K
D
S
K
Y
H
I
D
K
V
T
E
--
V
-----
I
I
K
G
--
V
K
-
R
Y
V
V
D
A
T
L
L
T
28
HHSearch
82.51
31%
-39
* C3 *
1QS1
-
?
A:
[264-456]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
-
L
D
F
K
-
N
D
IN
A
E
A
H
S
W
G
M
K
N
Y
E
E
W
A
K
D
L
T
D
S
Q
R
E
A
L
D
G
Y
A
R
-
Q
D
Y
K
E
I
N
N
Y
L
--
R
-----------
N
Q
-
G
G
S
---
G
---
N
--
E
K
L
D
A
Q
I
----
K
N
I
S
D
A
L
G
K
K
P
I
P
E
N
I
T
V
Y
R
W
----------
C
G
M
P
E
F
G
Y
Q
I
S
-------------
D
PL------
P
--
S
L
K
D
F
--------
E
---------
E
-------------
Q
F
L
N
T
----
I
K
E
D
K
G
Y
M
S
T
S
---
L
S
S
--
E
R
LA
A
F
G
S--
R
K
---
I
I
L
R
L
Q
V
P
K
G
S
T
G
------
A
Y
L
S
A
--
I
G
G
F
A
S
E
K
E
I
L
L
D
K
D
S
K
Y
H
I
D
K
V
T
E
V
I
I
-----
K
--
G
--
V
K
-
R
Y
V
V
D
-----
2
PsiBlast_PDB
81.98
27%
-32
- C3 -
4GF1
4
CRAX_BACCE
A:
[174-420]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
H
V
F
A
K
S
F
A
L
Y
Y
E
P
H
Y
K
E
A
L
K
S
Y
A
P
A
L
F
N
Y
M
L
E
L
D
Q
M
R
F
K
E
I
S
-
D
D
V
K
E
K
N
K
N
V
L
D
F
K
W
Y
T
--
R
K
A
E
S
W
G
V
Q
T
F
K
N
W
K
E
N
L
T
I
S
E
K
D
I
I
T
G
Y
T
G
-
S
K
Y
D
P
I
N
E
Y
L
--
R
K
Y
DGIG-----
G
D
-
L
D
K
---
K
---
S
--
K
K
A
L
E
K
I
E
N
Q
I
K
N
L
D
A
A
L
Q
K
S
K
I
T
E
N
L
I
V
Y
R
R
----------
V
S
E
L
Q
F
G
K
K
Y
E
-------------
D
--------
Y
--
N
L
R
----------
Q
---------
N
GIIN
E
E
K
V
M
E
L
E
S
N
F
K
G
Q
----
T
F
I
Q
H
N
Y
M
S
T
S
---
L
V
Q
DP
H
Q
--
S
Y
S
---
N
D
RYP
I
L
L
E
I
T
I
P
E
G
V
H
G
------
A
Y
I
A
D
--
M
S
E
Y
P
G
Q
Y
E
M
L
I
N
R
G
-------------------------------------
23
HHSearch
79.65
27%
-47
- C3 -
3BW8
1
ARC3_CLOLM
A:
[14-216]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
A
D
S
F
-
K
E
F
T
-
N
I
--
D
E
A
R
A
W
G
D
K
Q
F
A
K
Y
--
K
L
S
S
S
E
K
N
A
L
T
I
Y
T
R
-
N
-
A
A
R
I
N
G
P
L
--
R
-----------
A
N
-
Q
G
N
TNG
L
---
P
--
A
D
I
R
K
E
V
----
E
Q
I
D
K
S
F
T
K
M
Q
T
P
E
N
I
I
L
F
R
G
----------
D
D
P
G
Y
L
G
P
D
F
E
NTILNR-------
D
--------
G
--
T
I
N
K
A
V
F
E
Q
V
---
K
---------
L
-------------
R
F
K
G
K
----
D
R
K
E
Y
G
Y
I
S
T
S
---
L
V
N
--
G
S
--
A
F
A
G--
R
P
---
I
I
T
K
F
K
V
L
D
G
S
K
A
------
G
Y
I
E
P
--
I
S
T
F
K
G
Q
L
E
V
L
L
P
R
S
S
T
Y
T
I
S
D
M
Q
I
A
P
N
-----
N
--
K
--
Q
I
-
I
I
T
A
L
L
K
---
17
PsiBlast_PDB
79.40
29%
-48
- C3 -
2WN4
-
?
A:
[230-415]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
G
K
A
N
Y
N
D
W
S
N
K
L
T
P
N
E
L
A
D
V
N
D
Y
M
R
-
G
G
Y
T
A
I
N
N
Y
L
I
S
N
-----------
G
P
-
V
N
N
---
P
---
N
--
P
E
L
D
S
K
I
----
T
N
I
E
N
A
L
K
R
E
P
I
P
T
N
L
T
V
Y
R
R
SGPQEFGLTL
T
S
P
E
Y
--
D
F
N
K
-------------
L
--------
E
--
N
I
D
A
F
--------
K
---------
S
-------------
K
W
E
G
Q
----
A
L
S
Y
P
N
F
I
S
T
S
IG-
S
V
N
--
M
S
--
A
F
A
---
K
R
K--
I
V
L
R
I
T
I
P
K
G
S
P
G
------
A
Y
L
S
A
--
I
P
G
Y
A
G
E
Y
E
V
L
L
N
H
G
S
K
F
K
I
N
K
I
D
S
--
Y
K
----
D
--
G
--
T
I
T
K
L
I
V
D
-----
20
PsiBlast_PDB
78.97
29%
-55
- C3 -
2WN8
-
?
A:
[230-415]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
G
K
A
N
Y
N
D
W
S
N
K
L
T
P
N
E
L
A
D
V
N
D
Y
M
R
-
G
G
Y
T
A
I
N
N
Y
L
I
S
N
-----------
G
P
-
V
N
N
---
P
---
N
--
P
E
L
D
S
K
I
----
T
N
I
E
N
A
L
K
R
E
P
I
P
T
N
L
T
V
Y
R
R
SGPQEFGLTL
T
S
P
E
Y
--
D
F
N
K
-------------
L
--------
E
--
N
I
D
A
F
--------
K
---------
S
-------------
K
W
E
G
Q
----
A
L
S
Y
P
N
F
I
S
T
S
IG-
S
V
N
--
M
S
--
A
F
A
---
K
R
K--
I
V
L
R
I
T
I
P
K
G
S
P
G
------
A
Y
L
S
A
--
I
P
---
G
E
Y
E
V
L
L
N
H
G
S
K
F
K
I
N
K
I
D
S
--
Y
K
----
D
--
G
--
T
I
T
K
L
I
V
D
-----
19
PsiBlast_PDB
78.70
29%
-57
- C3 -
2WN7
1
?
A:
[273-458]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
G
K
A
N
Y
N
D
W
S
N
K
L
T
P
N
E
L
A
D
V
N
D
Y
M
R
-
G
G
Y
T
A
I
N
N
Y
L
I
S
N
-----------
G
P
-
V
N
N
---
P
---
N
--
P
E
L
D
S
K
I
----
T
N
I
E
N
A
L
K
R
E
P
I
P
T
N
L
T
V
Y
R
R
SGPQEFGLTL
T
S
P
E
Y
--
D
F
N
K
-------------
L
--------
E
--
N
I
D
A
F
--------
K
---------
S
-------------
K
W
E
G
Q
----
A
L
S
Y
P
N
F
I
S
T
S
IG-
S
V
N
--
M
S
--
A
F
A
---
K
R
K--
I
V
L
R
I
T
I
P
K
G
S
P
G
------
A
Y
L
S
A
--
I
P
G
Y
A
G
E
Y
E
V
L
L
N
H
G
S
K
F
K
I
N
K
I
D
S
--
Y
K
----
D
--
G
--
T
I
T
K
L
I
V
D
-----
24
HHSearch
78.25
29%
-47
- C3 -
1R45
4
ARC3_CBCP
A:
[4-203]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
F
-
T
E
F
T
-
N
V
--
E
E
A
K
K
W
G
N
A
Q
Y
K
K
Y
--
G
L
S
K
P
E
Q
E
A
I
K
F
Y
T
R
-
D
-
A
S
K
I
N
G
P
L
--
R
-----------
A
N
-
Q
G
N
---
E
NGL
P
--
A
D
I
L
Q
K
V
----
K
L
I
D
Q
S
F
S
K
M
K
M
P
Q
N
I
I
L
F
R
G
----------
D
D
P
A
Y
L
G
P
E
F
Q
DKILNK-------
D
--------
G
--
T
I
N
----------
K
T
V
F
E
Q
V
K
--
A
-------------
K
F
L
K
K
----
D
R
T
E
Y
G
Y
I
S
T
S
---
L
M
S
--
A
---
Q
F
G
G--
R
P
---
I
V
T
K
F
K
V
T
N
G
S
K
G
------
G
Y
I
D
P
--
I
S
Y
F
P
G
Q
L
E
V
L
L
P
R
N
N
S
Y
Y
I
S
D
M
Q
I
S
P
N
-----
N
--
R
--
Q
I
-
M
I
T
A
M
I
F
---
18
PsiBlast_PDB
77.32
29%
-55
- C3 -
2WN5
-
?
A:
[230-415]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
G
K
A
N
Y
N
D
W
S
N
K
L
T
P
N
E
L
A
D
V
N
D
Y
M
R
-
G
G
Y
T
A
I
N
N
Y
L
I
S
N
-----------
G
P
-
V
N
N
---
P
---
N
--
P
E
L
D
S
K
I
----
T
N
I
E
N
A
L
K
R
E
P
I
P
T
N
L
T
V
Y
R
R
SGPQEFGLTL
T
S
P
E
Y
--
D
F
N
K
-------------
L
--------
E
--
N
I
D
A
F
--------
K
---------
S
-------------
K
W
E
G
Q
----
A
L
S
Y
P
N
F
I
S
T
S
IG-
S
V
N
--
M
S
--
A
F
A
---
K
R
K--
I
V
L
R
I
T
I
P
K
G
S
P
G
------
A
Y
L
S
A
--
I
P
G
Y
--
E
Y
E
V
L
L
N
H
G
S
K
F
K
I
N
K
I
D
S
--
Y
K
----
D
--
G
--
T
I
T
K
L
I
V
D
-----
26
HHSearch
77.28
26%
-44
- C3 -
2J3X
12
?
A:
[216-423]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
E
-
L
D
F
Y
-
N
---
K
G
S
E
A
W
G
A
E
N
Y
G
D
Y
I
S
K
L
S
H
E
Q
L
G
A
L
E
G
Y
L
H
-
S
D
Y
K
A
I
N
S
Y
L
--
R
-----------
N
N
-
R
V
P
---
N
---
N
--
D
E
L
N
K
K
I
----
E
L
I
S
S
A
L
S
V
K
P
I
P
Q
T
L
I
A
Y
R
R
----------
V
D
G
I
P
F
D
L
P
S
D
-------------
F
SF
D
K
K
E
N-
G
E
I
I
A
D
K
Q
K
L
N
E
F
---
I
---------
D
-------------
K
W
T
G
K
----
E
I
E
N
L
S
F
S
S
T
S
---
L
K
S
--
T
P
S-
S
F
S
K--
R
R
---
F
I
F
R
L
R
L
S
E
G
A
I
G
------
A
F
I
Y
G
--
F
S
G
F
Q
D
E
Q
E
I
L
L
N
K
N
S
T
F
K
I
F
R
I
T
P
I
T
S
I
INRV
T
--
K
--
M
T
-
Q
V
V
I
D
A
----
10
PsiBlast_PDB
76.70
30%
-38
- C3 -
4H03
11
?
A:
[228-399]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
G
K
E
N
Y
S
D
W
S
N
K
L
T
P
N
E
L
A
D
V
N
D
Y
M
R
-
G
G
Y
T
A
I
N
N
Y
L
I
S
N
-----------
G
P
-
L
N
N
---
P
---
N
--
P
E
L
D
S
K
V
----
N
N
I
E
N
A
L
K
L
T
P
I
P
S
N
L
I
V
Y
R
R
SGPQEFGLTL
T
S
P
E
Y
--
D
F
N
K
-------------
I
--------
E
--
N
I
D
A
F
--------
K
---------
E
-------------
K
W
E
G
K
----
V
I
T
Y
P
N
F
I
S
T
S
IG-
S
V
N
--
M
S
--
A
F
A
---
K
R
K--
I
I
L
R
I
N
I
P
K
D
S
P
G
------
A
Y
L
S
A
--
I
P
G
Y
A
G
E
Y
E
V
L
L
N
H
G
S
K
F
K
I
N
K
V
-----------------------------
1
PsiBlast_PDB
76.66
27%
-26
- C3 -
4FXQ
4
CRAX_BACCE
A:
[174-426]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
H
V
F
A
K
S
F
A
L
Y
Y
E
P
H
Y
K
E
A
L
K
S
Y
A
P
A
L
F
N
Y
M
L
E
L
D
Q
M
R
F
K
E
I
S
-
D
D
V
K
E
K
N
K
N
V
L
D
F
K
W
Y
T
--
R
K
A
E
S
W
G
V
Q
T
F
K
N
W
K
E
N
L
T
I
S
E
K
D
I
I
T
G
Y
T
G
-
S
K
Y
D
P
I
N
E
Y
L
--
R
KYDG
E
I
I
P
N
I
G
G
D
-
L
D
K
---
K
---
S
--
K
K
A
L
E
K
I
E
N
Q
I
K
N
L
D
A
A
L
Q
K
S
K
I
T
E
N
L
I
V
Y
R
R
----------
V
S
E
L
Q
F
G
K
K
Y
E
-------------
D
--------
Y
--
N
L
R
----------
Q
---------
N
GIIN
E
E
K
V
M
E
L
E
S
N
F
K
G
Q
----
T
F
I
Q
H
N
Y
M
S
T
S
---
L
V
Q
DP
H
Q
--
S
Y
S
---
N
D
RYP
I
L
L
E
I
T
I
P
E
G
V
H
G
------
A
Y
I
A
D
--
M
S
E
Y
P
G
Q
Y
E
M
L
I
N
R
G
-------------------------------------
25
HHSearch
76.39
27%
-49
- C3 -
1OJQ
-
?
A:
[2-210]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
-
K
N
F
T
-
D
L
--
V
E
A
T
K
W
G
N
S
L
I
K
S
A
--
K
Y
S
S
K
D
K
M
A
I
Y
N
Y
T
K
-
N
-
S
S
P
I
N
T
P
L
--
R
-----------
S
A
-
N
G
D
VNK
L
---
S
--
E
N
I
Q
E
Q
V
----
R
Q
L
D
S
T
I
S
K
S
V
T
P
D
S
V
Y
V
Y
R
L
----------
L
N
L
D
Y
L
S
S
I
T
G
FT
R
E
D
L
H
M
L
Q
QTN
N
--------
G
--
Q
Y
N
E
A
L
-------
V
---------
S
K
L
N
N
---------
L
M
N
S
R
----
I
Y
R
E
N
G
Y
S
S
T
Q
---
L
V
S
--
G
A
--
A
L
A
G--
R
P
---
I
E
L
K
L
E
L
P
K
G
T
K
A
------
A
Y
I
D
S
KE
L
T
A
Y
P
G
Q
Q
E
V
L
L
P
R
G
T
E
Y
A
V
G
S
V
K
L
--
S
-----
D
--
N
KR
K
I
-
I
I
T
A
V
V
F
---
37
Fugue
76.26
26%
-41
- C3 -
1QS1
-
?
A:
[265-461]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
D
-
F
K
N
D
-
I
N
--
A
E
A
H
S
W
G
M
K
N
Y
E
E
W
A
K
D
L
T
D
S
Q
R
E
A
L
D
G
Y
A
R
-
Q
D
Y
K
E
I
N
N
Y
L
--
R
-----------
N
-Q
G
G
S
---
G
---
N
--
E
K
L
D
A
Q
I
----
K
N
I
S
D
A
L
G
K
K
P
I
P
E
N
I
T
V
Y
R
W
----------
C
G
M
P
E
F
G
--
Y
Q
-------------
I
--------
S
--
D
-------------PLPS
L
K
D
F
E
E
-------------
Q
F
L
N
T
----
I
K
E
D
K
G
Y
M
S
T
S
---
L
S
S
--
E
R
--
L
A
A
FGS
R
K
---
I
I
L
R
L
Q
V
P
K
----GSTGAY--
L
S
A
--
I
G
G
F
A
S
E
K
E
I
L
L
D
K
D
S
K
Y
H
I
D
K
V
T
E
--
V
-----
I
I
K
G
--
V
K
-
R
Y
V
V
D
A
T
L
L
T
14
PsiBlast_PDB
75.85
29%
-37
- C3 -
4H0V
11
?
A:
[228-399]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
G
K
E
N
Y
S
D
W
S
N
K
L
T
P
N
E
L
A
D
V
N
D
Y
M
R
-
G
G
Y
T
A
I
N
N
Y
L
I
S
N
-----------
G
P
-
L
N
N
---
P
---
N
--
P
E
L
D
S
K
V
----
N
N
I
E
N
A
L
K
L
T
P
I
P
S
N
L
I
V
Y
R
R
SGPQEFGLTL
T
S
P
E
Y
--
D
F
N
K
-------------
I
--------
E
--
N
I
D
A
F
--------
K
---------
E
-------------
K
W
E
G
K
----
V
I
T
Y
P
N
F
I
S
T
S
IG-
S
V
N
--
M
S
--
A
F
A
---
K
R
K--
I
I
L
R
I
N
I
P
K
D
S
P
G
------
A
Y
L
S
A
--
I
P
G
Y
A
G
S
Y
E
V
L
L
N
H
G
S
K
F
K
I
N
K
V
-----------------------------
15
PsiBlast_PDB
75.68
29%
-39
- C3 -
4H0Y
12
?
A:
[228-399]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
G
K
E
N
Y
S
D
W
S
N
K
L
T
P
N
E
L
A
D
V
N
D
Y
M
R
-
G
G
Y
T
A
I
N
N
Y
L
I
S
N
-----------
G
P
-
L
N
N
---
P
---
N
--
P
E
L
D
S
K
V
----
N
N
I
E
N
A
L
K
L
T
P
I
P
S
N
L
I
V
Y
R
R
SGPQEFGLTL
T
S
P
E
Y
--
D
F
N
K
-------------
I
--------
E
--
N
I
D
A
F
--------
K
---------
E
-------------
K
W
E
G
K
----
V
I
T
Y
P
N
F
I
S
T
S
IG-
S
V
N
--
M
S
--
A
F
A
---
K
R
K--
I
I
L
R
I
N
I
P
K
D
S
P
G
------
A
Y
L
S
A
--
I
P
G
Y
A
G
E
Y
S
V
L
L
N
H
G
S
K
F
K
I
N
K
V
-----------------------------
22
HHSearch
75.42
24%
-43
- C3 -
2BOV
-
ARC3_CBDP
B:
[44-244]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
Y
-
Q
E
F
T
-
N
I
--
D
Q
A
K
A
W
G
N
A
Q
Y
K
K
Y
--
G
L
S
K
S
E
K
E
A
I
V
S
Y
T
K
-
S
-
A
S
E
I
N
G
K
L
--
R
-----------
Q
N
-
K
G
V
---
I
NGF
P
--
S
N
L
I
K
Q
V
----
E
L
L
D
K
S
F
N
K
M
K
T
P
E
N
I
M
L
F
R
G
----------
D
D
P
A
Y
L
G
T
E
F
Q
NTLLNS-------
N
--------
G
--
T
I
N
----------
K
T
A
F
E
K
A
K
--
A
-------------
K
F
L
N
K
----
D
R
L
E
Y
G
Y
I
S
T
S
---
L
M
N
--
V
S
--
Q
F
A
G--
R
P
---
I
I
T
K
F
K
V
A
K
G
S
K
A
------
G
Y
I
D
P
--
I
S
A
F
A
G
Q
L
E
M
L
L
P
R
H
S
T
Y
H
I
D
D
M
R
L
S
-
S
-----
D
--
G
K-
Q
I
-
I
I
T
A
T
M
M
---
21
HHSearch
75.36
23%
-50
- C3 -
2C8E
1
ARC3_CBDP
E:
[5-204]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Y
-
Q
E
F
T
-
N
I
--
D
Q
A
K
A
W
G
N
A
Q
Y
K
K
Y
--
G
L
S
K
S
E
K
E
A
I
V
S
Y
T
K
-
S
-
A
S
E
I
N
G
K
L
--
R
-----------
Q
N
-
K
G
V
---
I
NGF
P
--
S
N
L
I
K
Q
V
----
E
L
L
D
K
S
F
N
K
M
K
T
P
E
N
I
M
L
F
R
G
----------
D
D
P
A
Y
L
G
T
E
F
Q
NTLLNS-------
N
--------
G
--
T
I
N
KTAFEKA---
K
---------
A
-------------
K
F
L
N
K
----
D
R
L
E
Y
G
Y
I
S
T
S
---
L
M
N
--
V
S
--
Q
F
A
G--
R
P
---
I
I
T
K
F
K
V
A
K
G
S
K
A
------
G
Y
I
D
P
--
I
S
A
F
A
G
Q
L
N
M
L
L
P
R
H
S
T
Y
H
I
D
D
M
R
L
S-
S
-----
D
G-
K
--
Q
I
-
I
I
T
A
T
M
M
---