@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu04190: (2016-06-07 )
MANYPKELPAQTQSRQPGIESEMNPSPVYEYEDYKGADKLKGKVALITGGDSGIGRAVSVAYAKEGADIAIVYKDEHEDAEETKKRVEQEGVKCLLIAGDVGEEEFCNEAVEKTVKELGGLDILVNNAGEQHPKESIKDITSEQLHRTFKTNFYSQFYLTKKAIDYLKPGSAIINTTSINPYVGNPTLIDYTATKGAINAFTRTMAQALVKDGIRVNAVAPGPIWTPLIPATFPEETVAQFGQDTPMGRPGQPVEHVGCYVLLASDESSYMTGQTLHVNGGNFVTT
Atome Classification :
(22 SA)
.........10........20........30........40........50-.........60........70..-......80........90..---......100-........110.......120.......----130.......140..-.....150.......160..-.....---170--........180..--.....190........200.......210........220.....------.-.230...--------------....240.......250.......260..--.....270.......280....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MANY
P
K
ELPAQTQSRQPGIESEMNPSP
V
Y
EYEDYK
G
A
D
KLK
G
K
V
A
L
I
TGG--DSGIG
R
A
V
S
V
A
Y
AKEGA
D
I
A
I
V
Y
-KDEHE
D
A
E
E
T
K
K
R
V
E
Q
EG
V
K
---
C
L
L
I
AGDV--G
E
E
E
F
C
N
E
A
V
E
K
T
V
K
E
LGG
L
D
I
L
VNNAG----EQ
H
P
K
E
S
I
K
D
I
T
S
E
Q
-
L
H
R
T
F
K
T
N
F
Y
S
Q
F
Y
L
T
K
K
A
I
-
D
YLKP---G
S
---
A
I
I
N
TTSINPYVG--N
P
T
L
I
D
-YTATK
G
A
I
N
A
F
T
R
T
M
A
Q
A
L
V
K-DG
I
R
V
N
AVAPGPIWTP------L-IPATF
P
E
--------------
E
T
V
A
Q
FGQDTPMGRPGQPV
E
H
V
G
C
Y
V
L
L
A--SDESSYMTG
Q
T
L
H
VNGG
N
F
VTT
27
PsiBlast_CBE
77.29
61%
-56
- C1 -
3I3O
5
?
B:
[13-289]
-------
M
P
A
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
--
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
-
L
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
---
C
V
L
L
P
G
D
L
--
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
----
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
-
S
H
L
K
Q
---
G
D
---
V
I
I
N
T
A
S
I
V
A
Y
E
G
--
N
E
T
L
I
D
-
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
-
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
------
L
-
I
P
S
S
F
D
E
--------------
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
--
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
--
23
PsiBlast_CBE
76.04
61%
-60
- C1 -
3I3O
1
?
F:
[22-289]
----------------
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
--
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
-
L
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
---
C
V
L
L
P
G
D
L
--
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
----
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
-
S
H
L
K
Q
---
G
D
---
V
I
I
N
T
A
S
I
V
A
Y
E
G
--
N
E
T
L
I
D
-
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
-
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
------
L
-
I
P
S
S
F
D
E
--------------
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
--
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
--
122
HHSearch
75.49
61%
-53
- C1 -
3IJR
5
?
A:
[12-290]
------
T
M
P
A
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
--
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
-
L
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
---
C
V
L
L
P
G
D
L
--
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
----
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
-
S
H
L
K
Q
---
G
D
---
V
I
I
N
T
A
S
I
V
A
Y
E
G
--
N
E
T
L
I
D
-
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
-
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
------
L
-
I
P
S
S
F
D
E
--------------
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
--
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
-
25
PsiBlast_CBE
74.73
61%
-54
- C1 -
3I3O
5
?
D:
[13-289]
-------
M
P
A
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
--
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
-
L
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
---
C
V
L
L
P
G
D
L
--
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
----
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
-
S
H
L
K
Q
---
G
D
---
V
I
I
N
T
A
S
I
V
A
Y
E
G
--
N
E
T
L
I
D
-
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
-
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
------
L
-
I
P
S
S
F
D
E
--------------
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
--
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
--
1
PsiBlast_PDB
74.68
61%
-55
- C1 -
3I3O
5
?
A:
[13-289]
-------
M
P
A
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
--
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
-
L
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
---
C
V
L
L
P
G
D
L
--
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
----
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
-
S
H
L
K
Q
---
G
D
---
V
I
I
N
T
A
S
I
V
A
Y
E
G
--
N
E
T
L
I
D
-
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
-
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
------
L
-
I
P
S
S
F
D
E
--------------
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
--
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
--
26
PsiBlast_CBE
74.65
61%
-54
- C1 -
3I3O
3
?
C:
[13-289]
-------
M
P
A
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
--
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
-
L
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
---
C
V
L
L
P
G
D
L
--
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
----
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
-
S
H
L
K
Q
---
G
D
---
V
I
I
N
T
A
S
I
V
A
Y
E
G
--
N
E
T
L
I
D
-
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
-
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
------
L
-
I
P
S
S
F
D
E
--------------
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
--
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
--
2
PsiBlast_PDB
74.51
60%
-53
- C1 -
3IJR
5
?
A:
[14-290]
--------
P
A
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
--
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
-
L
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
---
C
V
L
L
P
G
D
L
--
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
----
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
-
S
H
L
K
Q
---
G
D
---
V
I
I
N
T
A
S
I
V
A
Y
E
G
--
N
E
T
L
I
D
-
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
-
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
------
L
-
I
P
S
S
F
D
E
--------------
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
--
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
-
24
PsiBlast_CBE
74.23
61%
-53
- C1 -
3I3O
3
?
E:
[13-289]
-------
M
P
A
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
--
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
-
L
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
---
C
V
L
L
P
G
D
L
--
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
----
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
-
S
H
L
K
Q
---
G
D
---
V
I
I
N
T
A
S
I
V
A
Y
E
G
--
N
E
T
L
I
D
-
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
-
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
------
L
-
I
P
S
S
F
D
E
--------------
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
--
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
--
30
PsiBlast_CBE
71.91
47%
-59
- C1 -
3R3S
4
?
B:
[12-293]
---
Y
T
G
E
Y
P
K
Q
K
Q
P
A
-
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
--
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
---
A
V
L
L
P
G
D
L
--
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
G
G
L
D
I
L
A
L
V
A
G
----
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
-
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
-
P
L
L
P
K
---
G
A
---
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
--
S
P
H
L
L
D
-
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
-
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
------
L
Q
I
S
G
G
Q
T
Q
--------------
D
K
I
P
Q
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
--
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
E
H
L
--
21
PsiBlast_CBE
71.85
61%
-55
- C1 -
3I3O
6
?
H:
[17-289]
-----------
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
--
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
-
L
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
---
C
V
L
L
P
G
D
L
--
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
----
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
-
S
H
L
K
Q
---
G
D
---
V
I
I
N
T
A
S
I
V
A
Y
E
G
--
N
E
T
L
I
D
-
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
-
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
------
L
-
I
P
S
S
F
-------------------
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
--
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
--
29
PsiBlast_CBE
70.88
47%
-58
- C1 -
3R3S
3
?
C:
[12-293]
---
Y
T
G
E
Y
P
K
Q
K
Q
P
A
-
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
--
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
---
A
V
L
L
P
G
D
L
--
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
G
G
L
D
I
L
A
L
V
A
G
----
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
-
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
-
P
L
L
P
K
---
G
A
---
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
--
S
P
H
L
L
D
-
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
-
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
------
L
Q
I
S
G
G
Q
T
Q
--------------
D
K
I
P
Q
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
--
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
E
H
L
--
28
PsiBlast_CBE
70.32
47%
-57
- C1 -
3R3S
3
?
D:
[12-293]
---
Y
T
G
E
Y
P
K
Q
K
Q
P
A
-
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
--
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
---
A
V
L
L
P
G
D
L
--
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
G
G
L
D
I
L
A
L
V
A
G
----
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
-
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
-
P
L
L
P
K
---
G
A
---
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
--
S
P
H
L
L
D
-
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
-
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
------
L
Q
I
S
G
G
Q
T
Q
--------------
D
K
I
P
Q
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
--
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
E
H
L
--
3
PsiBlast_PDB
70.06
47%
-58
- C1 -
3R3S
3
?
A:
[12-293]
---
Y
T
G
E
Y
P
K
Q
K
Q
P
A
-
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
--
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
---
A
V
L
L
P
G
D
L
--
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
G
G
L
D
I
L
A
L
V
A
G
----
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
-
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
-
P
L
L
P
K
---
G
A
---
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
--
S
P
H
L
L
D
-
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
-
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
------
L
Q
I
S
G
G
Q
T
Q
--------------
D
K
I
P
Q
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
--
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
E
H
L
--
134
HHSearch
66.78
30%
-99
- C1 -
3AWD
-
?
A:
[5-259]
---------------------------------
Y
M
E
K
L
R
L
D
N
R
V
A
I
V
T
G
G
--
A
Q
N
I
G
L
A
C
V
T
A
L
A
E
A
G
A
R
V
I
I
A
D
-
L
D
E
A
-
M
A
T
K
A
V
E
D
L
R
M
E
G
H
D
---
V
S
S
V
V
M
D
V
--
T
N
T
E
S
V
Q
N
A
V
R
S
V
H
E
Q
E
G
R
V
D
I
L
V
A
C
A
G
----
I
C
I
S
E
V
K
A
E
D
M
T
D
G
Q
-
W
L
K
Q
V
D
I
N
L
N
G
M
F
R
S
C
Q
A
V
G
-
R
I
M
L
E
Q
K-
Q
G
---
V
I
V
A
I
G
S
M
S
G
L
I
V
N
R
P
Q
Q
Q
A
A
-
Y
N
A
S
K
A
G
V
H
Q
Y
I
R
S
L
A
A
E
W
A
P
-
H
G
I
R
A
N
A
V
A
P
T
Y
I
E
T
T
------
L
-
T
R
F
G
M
E
K
P
-------------
E
L
Y
D
A
W
I
A
G
T
P
M
G
R
V
G
Q
P
D
E
V
A
S
V
V
Q
F
L
A
--
S
D
A
A
S
L
M
T
G
A
I
V
N
V
D
A
G
F
T
V
--
37
PsiBlast_CBE
66.17
35%
-88
- C1 -
4MOW
1
?
B:
[11-254]
--------------------------------------
K
L
A
G
K
V
A
I
V
T
G
A
--
S
K
G
I
G
A
A
I
A
K
A
L
A
D
E
G
A
A
V
V
V
N
Y
-
A
S
S
K
A
G
A
D
A
V
V
S
A
I
T
E
A
G
G
R
---
A
V
A
V
G
G
D
V
--
S
K
A
A
D
A
Q
R
I
V
D
T
A
I
E
T
Y
G
R
L
D
V
L
V
N
N
S
G
V
Y
--
E
F
A
P
I
E
A
---
I
T
E
E
H
-
Y
R
R
Q
F
D
T
N
V
F
G
V
L
L
T
T
Q
A
A
V
-
K
H
L
G
E
---
G
A
---
S
I
I
N
I
S
S
V
V
T
S
I
T
--
P
P
A
S
A
V
-
Y
S
G
T
K
G
A
V
D
A
I
T
G
V
L
A
L
E
L
G
P
-
R
K
I
R
V
N
A
I
N
P
G
M
I
V
T
E
GTHSA----
G
S
D
L
E
A
--------------
Q
V
L
G
Q
----
T
P
L
G
R
L
G
E
P
N
D
I
A
S
V
A
V
F
L
A
--
S
D
D
A
R
W
M
T
G
E
H
L
V
V
S
G
G
-----
118
HHSearch
65.40
31%
-90
- C1 -
3GAF
-
?
A:
[5-253]
-----------------------------------
S
P
F
H
L
N
D
A
V
A
I
V
T
G
A
--
A
A
G
I
G
R
A
I
A
G
T
F
A
K
A
G
A
S
V
V
V
T
D
-
L
K
S
E
-
G
A
E
A
V
A
A
A
I
R
Q
A
G
G
K
---
A
I
G
L
E
C
N
V
--
T
D
E
Q
H
R
E
A
V
I
K
A
A
L
D
Q
F
G
K
I
T
V
L
V
N
N
A
G
----
G
G
G
P
K
-
P
F
-
D
M
P
M
S
D
-
F
E
W
A
F
K
L
N
L
F
S
L
F
R
L
S
Q
L
A
A
-
P
H
M
Q
K
A
G-
G
G
---
A
I
L
N
I
S
S
M
A
G
E
N
T
--
N
V
R
M
A
S
-
Y
G
S
S
K
A
A
V
N
H
L
T
R
N
I
A
F
D
V
G
P
-
M
G
I
R
V
N
A
I
A
P
G
A
I
K
T
D
------
A
-
L
A
T
V
L
T
P
--------------
E
I
E
R
A
M
L
K
H
T
P
L
G
R
L
G
E
A
Q
D
I
A
N
A
A
L
F
L
C
--
S
P
A
A
A
W
I
S
G
Q
V
L
T
V
S
G
G
G
V
Q
E
-
130
HHSearch
64.88
32%
-89
- C1 -
3WDS
4
?
A:
[7-262]
------------------------------------
I
F
D
L
S
G
R
K
A
I
V
T
G
G
--
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
-
L
D
V
M
-
A
A
Q
A
V
V
A
G
L
---
E
N
G
---
G
F
A
V
E
V
D
V
--
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
G
G
F
D
L
L
C
A
N
A
G
----
V
S
T
M
R
-
P
A
V
D
I
T
D
E
E
-
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
-
R
H
F
L
A
S
NT
K
G
---
V
I
V
N
T
A
S
L
A
A
K
V
G
--
A
P
L
L
A
H
-
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
-
K
N
I
R
V
N
C
V
C
P
G
F
V
K
T
A
------
M
-
Q
E
R
E
I
I
W
E
A
E
L
R
GMT
P
E
----
A
V
R
A
E
Y
V
S
L
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
--
S
D
A
A
R
F
M
T
G
Q
G
I
N
V
T
G
G
V
R
M
--
107
Fugue
64.59
30%
-104
- C1 -
1YBV
2
T4HR_MAGO7
A:
[14-283]
-------------
D
A
I
P
G
P
L
G
-------------
P
Q
S
A
S
L
E
G
K
V
A
L
V
T
G
A
GR--
G
I
G
R
E
M
A
M
E
L
G
R
R
G
C
K
V
I
V
N
Y
A-
N
S
T
E
S
A
E
E
V
V
A
A
I
K
K
N
---G
S
D
A
A
C
V
K
A
N
V
GV--
V
E
D
I
V
R
M
F
E
E
A
V
K
I
F
G
K
L
D
I
V
C
S
N
S
G
V
V
S
F
G
H
V
K
D
-
V
T
----
P
E
E
-
F
D
R
V
F
T
I
N
T
R
G
Q
F
F
V
A
R
E
A
Y
-
K
H
L
E
-I--
G
G
---
R
L
I
L
M
G
S
I
T
G
Q
A
K
--
A
V
P
K
H
A
V
Y
S
G
S
K
G
A
I
E
T
F
A
R
C
M
A
I
-
D
M
A
D
K
K
I
T
V
N
V
V
A
P
G
G
I
K
T
D
------
M
-
Y
H
A
V
C
R
E
YIPNGENLS
N
E
E
V
D
E
Y
A
A
V
Q
W
S
P
L
--
R
R
V
G
-
L
P
I
D
I
A
R
V
V
C
F
L
A
S
N
-
D
G
G
W
V
T
G
K
V
I
G
I
D
G
G
A
C
M
--
9
PsiBlast_PDB
63.64
35%
-87
- C1 -
4MOW
1
?
A:
[11-254]
--------------------------------------
K
L
A
G
K
V
A
I
V
T
G
A
--
S
K
G
I
G
A
A
I
A
K
A
L
A
D
E
G
A
A
V
V
V
N
Y
-
A
S
S
K
A
G
A
D
A
V
V
S
A
I
T
E
A
G
G
R
---
A
V
A
V
G
G
D
V
--
S
K
A
A
D
A
Q
R
I
V
D
T
A
I
E
T
Y
G
R
L
D
V
L
V
N
N
S
G
V
Y
--
E
F
A
P
I
E
A
---
I
T
E
E
H
-
Y
R
R
Q
F
D
T
N
V
F
G
V
L
L
T
T
Q
A
A
V
-
K
H
L
G
E
---
G
A
---
S
I
I
N
I
S
S
V
V
T
S
I
T
--
P
P
A
S
A
V
-
Y
S
G
T
K
G
A
V
D
A
I
T
G
V
L
A
L
E
L
G
P
-
R
K
I
R
V
N
A
I
N
P
G
M
I
V
T
E
GTHSAG
I
-
I
G
S
D
L
E
A
--------------
Q
V
L
G
Q
----
T
P
L
G
R
L
G
E
P
N
D
I
A
S
V
A
V
F
L
A
--
S
D
D
A
R
W
M
T
G
E
H
L
V
V
S
G
G
-----
49
PsiBlast_CBE
63.07
32%
-72
- C1 -
1G6K
1
DHG_BACME
E:
[5-249]
---------------------------------------
L
E
G
K
V
V
V
I
T
G
S
--
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
-
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
---
A
I
A
V
K
G
D
V
--
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
----
L
A
N
P
V
S
S
-
H
E
M
S
L
S
D
-
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
-
K
Y
F
V
E
---
N
D
IKG
T
V
I
N
M
S
S
V
H
E
K
I
P
--
W
P
L
F
V
H
-
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
-
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
------
I
-
N
A
E
K
F
A
D
P-------------
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
--
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
-----
83
PsiBlast_CBE
58.42
33%
-84
- C1 -
4BMN
5
?
C:
[7-249]
--------------------------------------
R
L
L
N
K
T
A
V
I
T
G
G
--
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
-
R
R
R
----
K
E
L
E
Q
A
A
A
E
I
G
R
N
---
V
T
A
V
K
A
D
V
--
T
K
L
E
D
L
D
R
L
Y
A
I
V
R
E
Q
R
G
S
I
D
V
L
F
A
N
S
G
----
A
I
E
Q
K
-
T
L
E
E
I
T
P
E
H
-
Y
D
R
T
F
D
V
N
V
R
G
L
I
F
T
V
Q
K
A
L
-
P
L
L
R
D
---
G
G
---
S
V
I
L
T
S
S
V
A
G
V
L
G
--
L
Q
A
H
D
T
-
Y
S
A
A
K
A
A
V
R
S
L
A
R
T
W
T
T
E
L
K
G
-
R
S
I
R
V
N
A
V
S
P
G
A
I
D
-------------------------------
E
L
R
A
K
F
A
A
A
T
P
L
G
R
V
G
R
P
E
E
L
A
A
A
V
L
F
L
A
--
S
D
D
S
S
Y
V
A
G
I
E
L
F
V
D
G
G
-----
16
PsiBlast_PDB
51.24
35%
-72
- C1 -
3OSU
15
FABG_STAAM
A:
[5-245]
------------------------------------------
K
S
A
L
V
T
G
A
--
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
A
V
N
Y
-
A
G
S
K
E
K
A
E
A
V
V
E
E
I
K
A
K
G
V
D
---
S
F
A
I
Q
A
N
V
--
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
G
S
L
D
V
L
V
N
N
A
G
------
I
T
R
D
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
R
Q
---
R
S
G
--
A
I
I
N
L
S
S
V
V
G
A
V
G
--
N
P
G
Q
A
N
-
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
-
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
------
M
-
T
D
A
-
L
S
D
--------------
E
L
K
E
Q
M
L
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
--
S
D
K
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
M
Y
---