@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0128: (2016-04-19 )
MQREIYDGEARLSWVLAALAGILGATAFTHSAGYFVTFMTGNSQRAVLGLFGDDAWMSVTASLLILFFVAGVVIASVCRRHFWAAHPHGPTVLTTFSLIFAAGVDIMLGGWHESMLDFVPILFVVFGIGALNTSFVKDGEVSVPLSYVTGTLVKMGQGIERHLAGGKVEDWLGYFLLHASFVLGAAAGGAISMVVTGPQMLAVAAVVCAATTGYTYLHADRRGLVNQKRPQPGKRLFRALRRGELDSGTSTPATNYGSS
Atome Classification :
(15 SA)
-----....---....------.10...--------...----..20........30..----......40.-.......--50.--------------------------------------......-.60........70.--------------.......80.........--90........100.----......110.-------------......120-.......-------.130....---...140.......150--........160.......170.---......180.-......190--------......-.200-----------------------....-------------....210--...----......220.---------......230.......240---------.......250-------........-------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----MQRE---IYDG------EARLSW--------VLA----ALAGILGATAFTHSAG----YFVTFMTGN-SQRAVLG--LFG--------------------------------------DDAWMS-VTASLLILFFVAGV--------------VIASVCRR-HFWAAHPHG--PTVLTTFSLIFAAG----VDIMLGGWHE-------------SMLDFVPI--LFVVFGI-------GALNTSFV---KDGEVSVPLSYVTGT---LVKMGQGIERHLAGGKVEDWLG---YFLLHASFVL-GAAAGGAIS--------MVVTGP-QML------------------------AVAA-------------VVCAA----TTG----YTYLHADRRG---------LVNQKRPQPGKRLFRALRR---------GELDSGTST--------PATNYGSS-------------------
13
Fugue
81.41
15%
-102
* C9 *
5C4I
3
OORB_MOOTA
C:
[1-312]
-----
M
L
D
R
---
I
A
S
I
------
K
K
A
P
D
E
EYYVPGHR
T
C
A
----
G
C
G
P
A
L
T
Y
R
L
V
A
K
A
A
G
----
P
N
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I
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I
G
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C
M
Y
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A
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--
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--------------------------------------
C
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W
----
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N
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--------------
A
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-
A
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DGGA
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Y
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--
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G
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F
T
---
P
P
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N
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I
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---
H
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A
-
T
A
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W
P
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D
--------
L
M
N
K
V
R
-
K
G
L
N
QE
G
P
A
Y
I
H
I
H
A
P
C
PKGWQFPADK
T
I
E
M
-------------
A
K
L
A
V
----
Q
T
G
M
F
Q
L
Y
E
Y
E
N
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K
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---------
S
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Q
K
R
FAHLK
P
E
H
I
A
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A
F
V
D
A
--------
R
C
A
E
V
G
I
T
V
P
V
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A
S-------------
15
Fugue
80.54
14%
-100
- C6 -
4P4M
5
?
A:
[92-378]
K
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-
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--------------------------------------
I
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-
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K
--------------
C
M
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------------------
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----
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-------
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P
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---
A
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KYL
E
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M
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--------
L
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T
G
S
-
K
N
F
------------------------
N
V
I
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-------------
R
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A
A
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----
S
K
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----
Y
L
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---
N
E
Y
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---------
L
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A
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A
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E
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--------
K
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L
GMPYAKPENRDP
10
Fugue
75.77
21%
-106
- C4 -
3WUW
4
KI3L1_HUMAN
G:
[16-301]
------------
K
P
F
L
------
S
A
W
P
S
A
--------
V
V
P
----
R
G
G
H
V
T
L
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Y
R
H
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F
N
----
N
F
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-
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GR
I
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Q
--------------------------------------
E
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HPHSPTGWSAPSNP
V
V
I
M
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N
-
H
------
R
K
--
P
S
L
L
A
H
P
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----
E
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I
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I
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--
F
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--
F
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E
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I
-------
S
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S
R
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V
GQI
H
D
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S
K
A
N
F
S
I
--
G
P
---
M
M
L
A
L
A
G
T
Y
R
C
Y
G
S
---
V
T
H
T
P
---
Y
Q
L
S
A
P
S
---------
D
P
L
D
--------
I
V
V
T
G
P
Y
E
K
P
------------------------
S
L
S
A
QPGPKVQAGESVT
L
S
C
S
S
----
R
S
S
----
Y
D
M
Y
H
L
S
R
E
G
---------
G
A
H
E
R
R
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P
A
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R
K
V
N
R
T
F
Q
A
---------
D
F
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L
G
G
T
Y
R
CFGSFRHS
P
Y
E
W
S
D
P
S
DPLLV--------------
17
Fugue
62.64
8%
-111
- C5 -
2P90
-
?
A:
[6-274]
DRM
Y
E
L
E
Y
P
---
S
P
E
V
------
S
G
Q
T
A
G
--------
G
P
T
----
L
I
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Y
A
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A
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A
V
E
----
S
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S
S
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M
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-
L
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--
S
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N
--------------------------------------
N
D
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L
I
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-
Y
R
S
R
R
P
V
V
V
I
E
H
N
E
--------------
V
T
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V
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Y
A
A
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---
H
T
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P
T
V
V
T
A
H
G
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---
R
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---
E
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G
K
N
-
V
S
G
Y
T
V
H
V
P
--------
H
Y
V
S
A
S
-
P
Y
P
------------------------
A
A
T
L
-------------
K
L
L
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----
I
A
D
----
S
A
D
L
N
L
P
L
L
A
---------
L
E
R
D
A
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K
V
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Q
L
M
E
Q
T
E
E
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---------
S
E
I
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V
V
G
A
--------
L
E
Q
Q
Y
D
S
E
L
ERYR--------------
11
Fugue
59.93
16%
-99
- C7 -
1KN0
-
RAD52_HUMAN
A:
[25-208]
-----
C
F
G
Q
---
C
Q
Y
T
------
A
E
E
Y
Q
A
--------
I
Q
K
----
A
L
R
Q
R
L
G
P
E
Y
I
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S
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M
A
GGG
Q
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-
V
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A
N
E
--
M
F
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--------------------------------------
Y
N
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W
A
H
-
S
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Q
N
V
D
F
V
D
L
N
--------------------------------------
N
G
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F
Y
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G
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C
A
F
----
V
R
V
Q
L
-----------------------------------------------------
K
D
G
S
Y
H
E
D
V
G
Y
G
V
S
E
---
G
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A
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K
E
A
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D
G
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---
R
A
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R
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N
A
L
-
G
N
C
------------------------------------------------------------------------------------
I
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---------
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P
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V
--------
E
E
A
R
Y
N
S
C
-------------------
12
Fugue
58.68
15%
-87
- C9 -
1W5C
9
PSBD_THEEB
D:
[1-350]
-----
M
T
I
A
---
I
G
R
A
P
A
E
RGW
F
D
I
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D
D
--------
W
L
K
R
DRF
V
F
V
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I
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A
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----
A
L
G
G
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G
T
-
T
F
V
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S
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Y
--
T
H
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A
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YLEGCNFLTVAVSTPANSMGHSLLLLWGPEAQGD
F
T
R
W
C
Q
-
L
G
G
L
W
T
F
I
A
L
H
G
A
F
--------------
G
L
I
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F
M
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-
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I
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VR
P
Y
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A
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I
A
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F
----
V
S
V
F
L
I
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P
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QSSWFFAPSFGV
A
A
I
F
R
F
L
L
F
--
F
Q
G
F
H
N
W
TLN
P
F
H
M
M
G
V
A
G
V
L
G
---
G
A
L
L
C
A
I
H
G
A
T
V
E
N
T
---
L
F
Q
D
G
E
G
A
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F
R
A
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N
P
T
Q
A
E
E
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---
Y
S
M
V
T
A
N
R
F
W
-
S
Q
I
F
G
I
A
F
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N
K
R
W
L
H
F
F
M
L
F
V
P
V
-
T
G
L
------------------------
W
M
S
A
-------------
I
G
V
V
G
L
ALN
L
R
S
----
Y
D
F
I
S
Q
E
I
R
A
A
E
D
P
EFETF
Y
T
K
N
L
L
L
N
E
G
I
R
A
W
M
A
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Q
D
---------
Q
P
H
E
N
F
V
F
P
--------
E
E
V
L
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R
G
N
-------------------
14
Fugue
32.96
20%
192
- C9 -
3UE5
1
B:
[35-59]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
M
C
E
P
S
P
R
E
Q
L
M
E
S
I
R
K
---------
G
K
E
L
K
Q
I
T
------------------------------------
7
HHSearch
30.79
14%
197
* C8 *
2BN8
-
CEDA_ECOLI
A:
[63-83]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
A
F
T
V
P
E
S
A
Q
R
W
A
N
Q
I
R
Q
---------
E
G
------------------------------------------
9
HHSearch
27.31
18%
77
- C8 -
4GC0
1
XYLE_ECOLI
A:
[7-28]
--------------
S
S
------
Y
I
F
S
I
T
--------
L
V
A
----
T
L
G
G
L
L
F
G
Y
D
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
22.23
42%
388
- C8 -
2L2L
-
B:
[232-243]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
L
E
E
A
L
M
A
---------
D
I
L
-----------------------------------------
2
HHSearch
21.94
14%
469
- C3 -
2KLU
-
CD4_HUMAN
A:
[413-426]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
S
E
K
K
T
S
Q
--------
S
P
H
R
F
----------------------
6
HHSearch
21.18
5%
83
- C8 -
4LDS
-
?
A:
[50-69]
--------------------------------------------------------------------------------------------------------------------------------------
S
M
L
I
G
A
I
V
G
A
--------------
G
S
S
G
P
L
A
D
-
K
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
15.25
11%
166
- C1 -
2MC5
-
?
A:
[5-22]
--------------------------------------
T
----
Q
I
S
G
Y
V
N
A
F
G
S
-
Q
R
G
S
----
V
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
14.68
14%
186
- C2 -
2HIY
-
?
A:
[34-54]
---------------------------------------------
L
G
L
E
K
V
E
S
Y
I
-------------
N
S
G
N
-
I
F
F
T
S
I
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
14.14
25%
239
- C8 -
5AYN
-
?
A:
[161-191]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
D
L
A
T
E
V
G
-
A
P
I
L
A
G
A
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------