@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0146: (2016-04-19 )
MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPTLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTARTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTAFAEFVTAERL
Atome Classification :
(20 SA)
------------.........10........-20........30........----------------.40........50...---.....60-.....-...70.........80........90........100--.-........110...--....120-------.-.-.---------......130.-......140.----...---------------------...---------------------150.------------------......160.--.--.-...--.170--..-.....180.......190-----...-....200.......210-..-..-.-..220..--.....230.....-.---.240...--....250---.-......260.......270.......280.......290.......300.......310----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------MRTHDDT
W
D
I
KTSV
G
A
T
A
V
-
M
V
A
A
A
R
AVETD-RPDPLIRD----------------PY
A
R
L
L
VTNAG
A
G
A
I
W
---
E
A
ML
D
P
T
-
L
V
A
K
A-AAID-
A
E
T
A
A
I
V
A
Y
L
R
S
Y
Q
A
V
R
T
N
F
F
D
T
Y
F
A
S
A
V
A
----
A
-
G
I
R
Q
V
V
I
L
ASGLDS--
R
A
Y
R
L
---------D-W-P---------A
G
T
I
V
Y
EIDQ-
P
K
V
L
S
Y
KSTT----LAE---------------------NGV---------------------TPSA------------------GRREV
P
A
D
L
R
--
Q
--
D
-
W
P
A
--
A
L
RD--AG-FDP
T
A
R
T
A
W
L
AE
G
L
L
M
YL-----PAE-
A
Q
D
R
L
F
T
QVG
A
V
S
VAGS-RI-AA-E-TAPVH
G
E
--
E
R
R
A
E
M
R
A
R
F
K
K
V
-
A
---
D
V
LGIEQ--TI
D
V
Q
E
L
---
V
-YHDQ
D
R
A
S
V
A
D
W
L
T
DHGWRARSQRA
P
D
E
M
R
R
V
G
R
W
VEGVPMAD
D
P
T
A
F
A
E
F
V
TAERL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
99.39
78%
-87
- C2 -
2CKD
-
Y2640_MYCLE
A:
[8-310]
-------------------
W
D
I
K
T
S
V
G
T
T
A
V
-
M
V
A
A
A
R
A
A
E
T
D
-
R
P
D
A
L
I
R
D
----------------
P
Y
A
K
L
L
V
T
N
T
G
A
G
A
L
W
---
E
A
M
L
D
P
S
-
M
V
A
K
V
-
E
A
I
D
-
A
E
A
A
A
M
V
E
H
M
R
S
Y
Q
A
V
R
T
N
F
F
D
T
Y
F
N
N
A
V
I
----
D
-
G
I
R
Q
F
V
I
L
A
S
G
L
D
S
--
R
A
Y
R
L
---------
D
-
W
-
P
---------
T
G
T
T
V
Y
E
I
D
Q
-
P
K
V
L
A
Y
K
S
T
T
----
L
A
E
---------------------
H
G
V
---------------------
T
P
T
A
------------------
D
R
R
E
V
P
I
D
L
R
--
Q
--
D
-
W
P
P
--
A
L
R
S
--
A
G
-
F
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
-----
P
A
T
-
A
Q
D
G
L
F
T
E
I
G
G
L
S
A
V
G
S
-
R
I
-
A
V
-
E
-
T
S
P
L
H
G
D
--
E
W
R
E
Q
M
Q
L
R
F
R
R
V
-
S
---
D
A
L
G
F
E
Q
--
A
V
D
V
Q
E
L
---
I
-
Y
H
D
E
N
R
A
V
V
A
D
W
L
N
R
H
G
W
R
A
T
A
Q
S
A
P
D
E
M
R
R
V
G
R
W
G
D
G
V
P
M
A
D
D
K
D
A
F
A
E
F
V
T
A
H
R
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
99.13
77%
-87
- C2 -
2CKD
-
Y2640_MYCLE
A:
[8-310]
-------------------
W
D
I
K
T
S
V
G
T
T
A
V
-
M
V
A
A
A
R
A
A
E
T
D
-
R
P
D
A
L
I
R
D
----------------
P
Y
A
K
L
L
V
T
N
T
G
A
G
A
L
W
---
E
A
M
L
D
P
S
-
M
V
A
K
V
-
E
A
I
D
-
A
E
A
A
A
M
V
E
H
M
R
S
Y
Q
A
V
R
T
N
F
F
D
T
Y
F
N
N
A
V
I
----
D
-
G
I
R
Q
F
V
I
L
A
S
G
L
D
S
--
R
A
Y
R
L
---------
D
-
W
-
P
---------
T
G
T
T
V
Y
E
I
D
Q
-
P
K
V
L
A
Y
K
S
T
T
----
L
A
E
---------------------
H
G
V
---------------------
T
P
T
A
------------------
D
R
R
E
V
P
I
D
L
R
--
Q
--
D
-
W
P
P
--
A
L
R
S
--
A
G
-
F
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
-----
P
A
T
-
A
Q
D
G
L
F
T
E
I
G
G
L
S
A
V
G
S
-
R
I
-
A
V
-
E
-
T
S
P
L
H
G
D
--
E
W
R
E
Q
M
Q
L
R
F
R
R
V
-
S
---
D
A
L
G
F
E
Q
--
A
V
D
V
Q
E
L
---
I
-
Y
H
D
E
N
R
A
V
V
A
D
W
L
N
R
H
G
W
R
A
T
A
Q
S
A
P
D
E
M
R
R
V
G
R
W
G
D
G
V
P
M
A
D
D
K
D
A
F
A
E
F
V
T
A
H
R
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
94.30
78%
-91
- C2 -
2UYQ
1
Y2640_MYCLE
A:
[14-310]
-------------------------
V
G
T
T
A
V
-
M
V
A
A
A
R
A
A
E
T
D
-
R
P
D
A
L
I
R
D
----------------
P
Y
A
K
L
L
V
T
N
T
G
A
G
A
L
W
---
E
A
M
--------------
D
-
A
E
A
A
A
M
V
E
H
M
R
S
Y
Q
A
V
R
T
N
F
F
D
T
Y
F
N
N
A
V
I
----
D
-
G
I
R
Q
F
V
I
L
A
S
G
L
D
S
--
R
A
Y
R
L
---------
D
-
W
-
P
---------
T
G
T
T
V
Y
E
I
D
Q
-
P
K
V
L
A
Y
K
S
T
T
----
L
A
E
---------------------
H
G
V
---------------------
T
P
T
A
------------------
D
R
R
E
V
P
I
D
L
R
--
Q
--
D
-
W
P
P
--
A
L
R
S
--
A
G
-
F
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
-----
P
A
T
-
A
Q
D
G
L
F
T
E
I
G
G
L
S
A
V
G
S
-
R
I
-
A
V
-
E
-
T
S
P
L
H
G
D
--
E
W
R
E
Q
M
Q
L
R
F
R
R
V
-
S
---
D
A
L
----------------
I
-
Y
H
D
E
N
R
A
V
V
A
D
W
L
N
R
H
G
W
R
A
T
A
Q
S
A
P
D
E
M
R
R
V
G
R
W
G
D
G
V
P
M
A
D
D
K
D
A
F
A
E
F
V
T
A
H
R
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
93.02
78%
-87
- C2 -
2UYO
-
Y2640_MYCLE
A:
[14-310]
-------------------------
V
G
T
T
A
V
-
M
V
A
A
A
R
A
A
E
T
D
-
R
P
D
A
L
I
R
D
----------------
P
Y
A
K
L
L
V
T
N
T
G
A
G
A
L
W
---
E
A
M
--------------
D
-
A
E
A
A
A
M
V
E
H
M
R
S
Y
Q
A
V
R
T
N
F
F
D
T
Y
F
N
N
A
V
I
----
D
-
G
I
R
Q
F
V
I
L
A
S
G
L
D
S
--
R
A
Y
R
L
---------
D
-
W
-
P
---------
T
G
T
T
V
Y
E
I
D
Q
-
P
K
V
L
A
Y
K
S
T
T
----
L
A
E
---------------------
H
G
V
---------------------
T
P
T
A
------------------
D
R
R
E
V
P
I
D
L
R
--
Q
--
D
-
W
P
P
--
A
L
R
S
--
A
G
-
F
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
-----
P
A
T
-
A
Q
D
G
L
F
T
E
I
G
G
L
S
A
V
G
S
-
R
I
-
A
V
-
E
-
T
S
P
L
H
G
D
--
E
W
R
E
Q
M
Q
L
R
F
R
R
V
-
S
---
D
A
------------
E
L
---
I
-
Y
H
D
E
N
R
A
V
V
A
D
W
L
N
R
H
G
W
R
A
T
A
Q
S
A
P
D
E
M
R
R
V
G
R
W
G
D
G
V
P
M
A
D
D
K
D
A
F
A
E
F
V
T
A
H
R
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
90.81
78%
-84
- C2 -
2UYO
-
Y2640_MYCLE
A:
[14-310]
-------------------------
V
G
T
T
A
V
-
M
V
A
A
A
R
A
A
E
T
D
-
R
P
D
A
L
I
R
D
----------------
P
Y
A
K
L
L
V
T
N
T
G
A
G
A
L
W
---
E
A
M
--------------
D
-
A
E
A
A
A
M
V
E
H
M
R
S
Y
Q
A
V
R
T
N
F
F
D
T
Y
F
N
N
A
V
I
----
D
-
G
I
R
Q
F
V
I
L
A
S
G
L
D
S
--
R
A
Y
R
L
---------
D
-
W
-
P
---------
T
G
T
T
V
Y
E
I
D
Q
-
P
K
V
L
A
Y
K
S
T
T
----
L
A
E
---------------------
H
G
V
---------------------
T
P
T
A
------------------
D
R
R
E
V
P
I
D
L
R
--
Q
--
D
-
W
P
P
--
A
L
R
S
--
A
G
-
F
D
P
S
A
R
T
A
W
L
A
E
G
L
L
M
Y
L
-----
P
A
T
-
A
Q
D
G
L
F
T
E
I
G
G
L
S
A
V
G
S
-
R
I
-
A
V
-
E
-
T
S
P
L
H
G
D
--
E
W
R
---
E
Q
M
Q
L
R
F
-
R
R
V
S
D
A
------------
E
L
---
I
-
Y
H
D
E
N
R
A
V
V
A
D
W
L
N
R
H
G
W
R
A
T
A
Q
S
A
P
D
E
M
R
R
V
G
R
W
G
D
G
V
P
M
A
D
D
K
D
A
F
A
E
F
V
T
A
H
R
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
59.74
17%
-59
- C2 -
3IEI
3
LCMT1_HUMAN
A:
[25-286]
------------------------
G
V
R
G
T
C
E
-
D
A
S
L
C
K
R
F
A
V
S
-
I
--
G
Y
W
H
D
----------------
P
Y
I
Q
H
F
V
R
L
S
K
E
------------------------------
R
K
A
P
E
I
N
R
G
Y
F
A
R
V
H
G
V
S
Q
L
I
K
A
F
L
R
K
---
T
E
C
H
C
Q
I
V
N
L
G
A
G
M
D
T
--
T
F
W
R
L
---------
K
-
D
-
E
DL-------
L
S
S
K
Y
F
E
V
D
F
-
P
M
I
V
T
R
K
L
H
S
----
I
K
C
---------------------
K
P
P
L
S
S
P
I
L
E
L
HSEDTLQMDGH
I
-
L
D
S
K
------------------
R
Y
A
V
I
G
A
D
L
R
--
D
L
S
E
-
L
E
E
--
K
L
K
K
--
C
N
-
M
N
T
Q
L
P
T
L
L
I
A
E
C
V
L
V
Y
M
-----
T
P
E
-
Q
S
A
N
L
L
K
W
A
A
N
S
F
E
R
A
M
-
F
I
-
N
Y
-
E
-
Q
V
N
M
G
D
R
---
F
G
---
Q
I
M
I
E
N
L
-
R
---
R
-
R
Q
------
C
D
L
A
G
V
---
E
T
C
K
S
L
--
E
S
Q
K
E
R
L
L
S
N
G
W
E
T
A
S
--
A
V
D
M
M
E
L
Y
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
55.15
13%
-32
- C2 -
1RJD
3
LCMT1_YEAST
A:
[2-329]
--------------------
E
R
I
I
Q
Q
T
D
Y
D
A
-
L
S
C
K
L
A
A
I
S
V
G
Y
L
P
S
S
G
L
Q
R
----------------
L
S
V
D
L
S
K
K
Y
T
E
W
H
R
S
Y
---
L
I
T
L
K
K
F
-
S
R
R
A
F
-
G
K
V
D
-
K
A
M
R
S
S
F
P
V
M
N
Y
G
T
Y
L
R
T
V
G
I
D
A
A
I
L
E
F
L
V
----
A
N
E
K
V
Q
V
V
N
L
G
C
G
S
D
L
--
R
M
L
P
L
---------
L
-
Q
M
F
---------
P
H
L
A
Y
V
D
I
D
Y
-
N
E
S
V
E
L
K
N
S
I
----
L
R
E
---------------------
S
E
I
---------------------
L
R
I
S
L
GLSKEDTAKSPFLIDQG
R
Y
K
L
A
A
C
D
L
N
D-
I
--
T
-
E
T
T
--
R
L
L
D
--
V
C
-
T
K
R
E
I
P
T
I
V
I
S
E
C
L
L
C
Y
M
-----
H
N
N
-
E
S
Q
L
L
I
N
T
I
M
S
K
F
S
H
G
L
-
W
I
-
S
Y
-
D
P
I
G
G
S
Q
P
N
--
D
R
F
G
A
I
M
Q
S
N
L
K
E
-
S
---
R
N
L
E
M
P
T
--
L
M
T
Y
N
S
K
---
E
-
K
Y
A
S
R
W
S
A
A
P
N
V
I
V
N
D
M
W
E
I
F
N
A
Q
I
P
E
S
E
R
K
R
L
R
S
L
Q
F
L
D
E
L
E
E
L
K
V
M
Q
T
H
Y
I
L
M
K
A
Q
W
H---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
51.11
13%
-45
* C2 *
1RJD
3
LCMT1_YEAST
A:
[2-297]
----------------------
E
R
I
I
Q
Q
T
D
Y
-
D
A
L
S
C
K
L
A
A
I
S
-
V
--
G
Y
L
P
S
----------------
S
G
L
Q
R
L
S
V
D
L
S
K
K
Y
T
E
W
H
R
S
Y
L
-
I
T
L
K
K
F
S
R
R
A
F
G
K
V
D
K
A
M
R
S
S
F
P
V
M
N
Y
G
T
Y
L
R
T
V
G
I
D
A
A
I
L
E
F
L
V
A
---
N
-
E
K
V
Q
V
V
N
L
G
C
G
S
D
L
--
R
M
L
P
L
---------
L
-
Q
M
F
---------
P
H
L
A
Y
V
D
I
D
Y
-
N
E
S
V
E
L
K
N
S
I
----
L
R
E
---------------------
S
E
I
L
R
I
S
L
GLSKEDTAKSPFL---
I
D
Q
G
------------------
R
Y
K
L
A
A
C
D
L
N
--
D
I
-
T
-
E
T
T
--
R
L
L
D
--
V
C
-
T
K
R
E
I
P
T
I
V
I
S
E
C
L
L
C
Y
M
-----
H
N
N
-
E
S
Q
L
L
I
N
T
I
M
S
K
F
S
H
G
L
-
W
I
-
S
Y
-
D
-
P
I
G
G
S
Q
P
ND
R
F
G
---
A
I
M
Q
S
N
L
-
K
---
E
S
R
N
------
L
E
M
P
T
L
---
M
T
Y
N
S
K
--
E
K
Y
A
S
R
W
S
-
A
A
-
P
N
V
--
I
V
N
D
M
W
E
I
F
N
A
Q
I
P
E
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
50.14
15%
-49
- C2 -
2ZWA
2
TYW4_YEAST
A:
[19-321]
-----------------
R
K
K
Y
A
D
L
A
I
Q
G
T
N
N
-
S
S
I
A
S
K
R
S
-
V
E
-
L
--
L
Y
L
P
K
LSSANNFQMDKNN
K
L
L
E
Y
F
K
F
F
V
P
K
K
I
-------------------------------
K
R
S
P
C
I
N
R
G
Y
W
L
R
L
F
A
I
R
S
R
L
N
S
I
I
E
Q
TPQ
D
-
K
K
I
V
V
V
N
L
G
C
G
Y
D
P
--
L
P
F
Q
L
---------
L
-
D
-
T
NNIQSQQYH
D
R
V
S
F
I
D
I
D
Y
-
S
D
L
L
K
I
K
I
E
L
----
I
K
T
---------------------
I
P
E
L
S
K
I
I
GLSEDKDYVDDSNVD
F
L
T
T
P
------------------
K
Y
L
A
R
P
C
D
L
N
--
D
S
-
K
M
F
S
T
--
L
L
N
E
C
-
Q
L
-
Y
D
P
N
V
V
K
V
F
V
A
E
V
S
L
A
Y
M
-----
K
P
E
-
R
S
D
S
I
I
E
A
T
S
K
-
M
E
N
S
H
-
F
I
-
I
L
-
E
-
Q
L
I
P
K
G
P
FE
P
F
S
---
K
Q
M
L
A
H
F
-
K
---
R
-
N
D
------
S
P
L
Q
S
V
---
L
K
Y
N
T
I
--
E
S
Q
V
Q
R
F
N
K
L
G
F
A
Y
V
N
--
V
G
D
M
F
Q
L
W
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
50.13
17%
-44
- C2 -
2ZWA
6
TYW4_YEAST
A:
[16-694]
Q
E
R
R
K
K
Y
A
D
L
A
I
Q
G
T
N
N
S
S
I
A
S
K
R
S
V
E
L
L
-
Y
-
L
P
K
L
S
S
A
N
N
F
Q
-
M
D
K
N
N
K
L
L
----------------
E
Y
F
K
F
F
V
P
K
K
I
K
R
------
S
P
C
I
N
R
G
-
Y
W
L
R
L
-
F
A
I
R
-
S
R
L
N
S
I
I
E
Q
T
P
Q
----------------------
D
-
K
K
I
V
V
V
N
L
G
C
G
Y
D
P
--
L
P
F
Q
L
L
DTNNIQSQ
Q
-
Y
-
H
---------
D
R
V
S
F
I
D
I
D
Y
-
S
D
L
L
K
I
K
I
E
L
----
I
K
T
I
P
E
L
S
K
I
I
GLSEDKDYVDDSN
V
D
F
---------------------
L
T
T
P
------------------
K
Y
L
A
R
P
C
D
L
N
D
S
K
--
M
-
F
S
T
--
L
L
N
E
--
C
Q
L
Y
D
P
N
V
V
K
V
F
V
A
E
V
S
L
A
Y
M
-----
K
P
E
-
R
S
D
S
I
I
E
A
T
S
K
M
E
N
S
H
F
-
I
I
-
L
E
-
Q
-
L
I
P
K
G
P
F
E-
P
F
S
K
Q
M
L
A
H
F
K
R
N
D
S
---
P
L
Q
S
V
L
K
Y
N
T
I
E
S
Q
V
Q
---
R
-
F
N
K
L
G
F
A
Y
V
N
V
G
D
M
F
Q
L
W
E
S
A
D
E
A
T
K
K
E
L
L
K
V
E
P
F
-------
D
E
L
E
E
F
H
L
F
C
H
H
Y
V
L
C
H
A
T
NYKEFAFTQGFLFDRINLTVDED
Y
Q
L
L
E
C
E
C
PINRKF
G
D
V
D
V
AGN
D
V
F
Y
M
G
GSNPYRVN
E
I
L
Q
L
S
I
H
YD
K
I
D
M
K
N
I
E
V
SSSEVPVARMC
H
T
F
T
T
I
SRNN
Q
L
L
L
I
G
GRKAPHQGLS
D
N
W
I
F
D
MKTR
E
W
S
M
I
KSLS
H
T
R
F
R
H
S
A
C
S
L
PDG
N
V
L
I
L
G
GVTEGPA
M
L
L
Y
NVTEEIFKDVTPKDEFFQ
N
S
L
V
S
A
G
L
E
F
D
PVSK
Q
G
I
I
L
G
GGFMDQTTVSDKA
I
I
F
K
Y
D
AENATEPITVI
K
K
L
Q
H
PLFQRYG
S
Q
I
K
Y
ITPR
K
L
L
I
V
G
G
T
S
PS
G
L
F
D
RTNS
I
I
S
L
DPLSE
T
L
T
S
IPIS
R
R
I
W
E
D
H
SLMLAG
F
S
L
V
S
TT
I
H
I
I
G
G
G
A
TCYGF
G
S
V
T
N
V
G
L
K
L
I
A
IA
29
HHSearch
44.80
15%
-42
- C2 -
5EEH
7
DNRK_STRPE
A:
[199-351]
----------------------------------------------------------------------------------------------------------------------------------------------
N
V
R
H
V
L
D
V
G
G
G
K
G
G
--
F
A
A
A
I
---------
A
R
R
-
A
---------
P
H
V
S
A
T
V
L
E
M
-
A
G
T
V
D
T
A
R
S
Y
----
L
K
D
---------------------
E
G
L
-----------------------
S
D
------------------
R
V
D
V
V
E
G
D
F
F
--
E
--
P
-
L
---------------
P
R
K
A
D
A
I
I
L
S
F
V
L
L
N
W
-----
P
D
H
-
D
A
V
R
I
L
T
R
C
A
E
A
L
E
P
G
G
-
R
I
L
I
H
-
E
-
R
D
D
L
H
E
N
--
S
F
N
----
E
Q
F
T
E
L
-
D
---
L
R
--
M
L
----
V
F
L
G
G
A
-----
L
R
T
R
--
E
K
W
D
G
L
A
A
S
A
G
L
V
V
E
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
43.19
12%
-49
- C2 -
2P8J
6
?
A:
[23-179]
----------------------------------------------------------------------------------------------------------------------------------------------
L
D
K
T
V
L
D
C
G
A
G
G
D
L
--
P
P
L
S
I
---------
F
-
V
-
E
---------
D
G
Y
K
T
Y
G
I
E
I
S
D
L
Q
L
K
K
A
E
N
F
----
S
R
E
---------------------
N
-------------------------
N
F
------------------
K
L
N
I
S
K
G
D
I
R
--
K
----
L
P
----
F
K
--------
D
E
S
M
S
F
V
Y
S
Y
G
T
I
F
H
M
-----
R
K
N
-
D
V
K
E
A
I
D
E
I
K
R
V
L
K
P
G
G
-
L
A
-
C
I
-
N
-
F
L
T
T
K
D
E
--
R
Y
N
K
-
G
E
K
I
G
E
G
E
-
F
----
L
Q
-------
L
E
-
G
E
K
V
I
H
S
-
Y
V
S
L
--
E
E
A
D
K
Y
F
K
D
M
K
V
L
F
K
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
42.96
11%
-53
- C2 -
4IV0
2
?
A:
[71-220]
--------------------------------------------------------------------------------------------------------------------------------------------
D
-
A
N
S
K
V
L
D
I
G
S
G
L
G
G
--
G
C
K
Y
I
---------
N
-
E
-
K
---------
Y
G
A
H
V
H
G
V
D
I
C
E
K
M
V
T
I
A
K
L
R
----
N
Q
D
---------------------
K
--------------------------
A
------------------
K
I
E
F
E
A
K
D
I
L
--
K
--
K
------
D
F
--------
P
E
S
T
F
D
M
I
Y
S
R
D
S
I
L
H
L
-----
S
Y
A
-
D
K
K
M
L
F
E
K
C
Y
K
W
L
K
P
N
G
-
I
L
-
L
I
-
T
-
D
Y
C
A
D
K
I
--
E
N
W
------
D
E
E
F
-
K
---
A
-
Y
-
I
-----
K
K
R
K
-
Y
---
T
-
L
M
P
I
--
Q
E
Y
G
D
L
I
K
S
C
K
F
Q
N
V
E
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
42.95
22%
-62
- C2 -
3G8Q
2
CDAT8_METKA
A:
[1-278]
---------------------
M
K
V
S
L
A
G
Q
T
V
D
V
K
K
I
L
N
E
I
P
K
--------
R
T
----------------
V
T
A
A
L
L
E
---
G
G
E
I
V
A
---
V
E
E
A
D
D
E
-
H
A
E
R
K
-
L
V
R
R
-
H
D
V
E
G
K
V
V
F
V
T
A
R
P
C
-------
L
Y
C
A
R
E
L
A
E
---
A
-
G
V
A
G
V
V
Y
L
G
R
G
R
G
L
--
G
P
Y
Y
L
---------
A
-
R
-----------
S
G
V
E
V
V
E
V
H
P
-
D
E
P
L
G
Y
D
P
V
D
RLD
V
L
L
T
---------------------
F
G
G
---------------------
N
P
Y
L
------------------
T
E
E
D
V
A
A
R
V
Y
--
C
--
L
-
L
T
G
--
R
G
F
D
--
A
D
-
I
A
P
A
P
E
---
N
L
S
G
R
V
E
I
M
V
TRGD
P
D
E
-
A
V
E
L
L
K
E
E
L
-------
P
-
V
F
-
R
I
-
R
-
R
F
L
I
S
G
E
--
F
D
R
D
E
L
R
E
R
I
L
E
D
-
I
---
E
P
R
-
I
L
D
--
P
F
A
V
R
A
R
---
I
-
A
R
A
G
A
F
S
S
---------
S
R
E
A
E
V
F
I
G
D
V
L
T
S
V
G
R
---
E
V
N
L
N
D
P
R
T
V
V
T
V
D
V
L
G
P
R
V
S
V
G
V
E
K
R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
42.63
15%
-61
- C2 -
5CVD
1
NTM1A_HUMAN
A:
[67-224]
----------------------------------------------------------------------------------------------------------------------------
K
F
L
Q
R
F
L
R
E
G
P
N
K---
T
-
G
T
S
C
A
L
D
C
G
A
G
I
G
R
--
I
T
K
R
L
---------
L
-
L
-
P
---------
L
F
R
E
V
D
M
V
D
I
T
E
D
F
L
V
Q
A
K
T
Y
----
L
G
E
---------------------
E
G
------------------------
K
R
------------------
V
R
N
Y
F
C
C
G
L
Q
--
D
--
F
--
T
------------
P
E
P
D
S
Y
D
V
I
W
I
Q
W
V
I
G
H
L
-----
T
D
Q
-
H
L
A
E
F
L
R
R
C
K
G
S
L
R
P
N
G
-
I
I
-
V
I
-
K
-
D
N
M
A
Q
E
G
----
V
--------
I
L
---------------
D
D
V
D
S
S
---
V
-
C
R
D
L
--
D
V
V
R
R
I
I
C
S
A
G
L
S
L
L
A
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
42.44
12%
-58
- C2 -
1XTP
1
?
A:
[82-235]
------------------------------------------------------------------------------------------------------------------------------
S
R
N
F
I
A
S
L
P
G
----
H
-
G
T
S
R
A
L
D
C
G
A
G
I
G
R
--
I
T
K
N
L
---------
L
-
T
-
K
---------
L
Y
A
T
T
D
L
L
E
P
V
K
H
M
L
E
E
A
K
R
E
----
L
A
G
---------------------
M
--------------------------
P
------------------
V
G
K
F
I
L
A
S
M
E
--
T
--
A
------
T
L
--------
P
P
N
T
Y
D
L
I
V
I
Q
W
T
A
I
Y
L
-----
T
D
A
-
D
F
V
K
F
F
K
H
C
Q
Q
A
L
T
P
N
G
-
Y
I
-
F
F
-
K
-
E
N
C
S
--
D
--
R
F
----------
L
-
V
-------------
D
K
E
D
S
S
---
L
-
T
R
S
D
--
I
H
Y
K
R
L
F
N
E
S
G
V
R
V
V
K
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
41.49
13%
-44
- C2 -
3MCZ
1
?
A:
[178-336]
--------------------------------------------------------------------------------------------------------------------------------------------
A
-
R
A
R
T
V
I
D
L
A
G
G
H
G
T
--
Y
L
A
Q
V
---------
L
R
R
-
H
---------
P
Q
L
T
G
Q
I
W
D
L
-
P
T
T
R
D
A
A
R
K
T
----
I
H
A
---------------------
H
D
L
-----------------------
G
G
------------------
R
V
E
F
F
E
K
N
L
L
--
D
--
A
---
R
--
N
F
E
--------
G
G
A
A
D
V
V
M
L
N
D
C
L
H
Y
F
-----
D
A
R
-
E
A
R
E
V
I
G
H
A
A
G
L
V
K
P
G
G
-
A
L
L
I
L
-
T
-
M
T
M
N
D
D
R
--
V
T
P
-----
A
L
S
A
D
-
F
---
S
-
L
H
M
M
---
V
N
T
N
H
G
E
-----
L
H
P
T
--
P
W
I
A
G
V
V
R
D
A
G
L
A
V
G
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
41.38
18%
-47
- C2 -
3GIW
3
?
A:
[58-204]
----------------------------------------------------------------------------------------------------------------------
H
M
R
A
N
R
D
W
M
N
R
A
V
A
H
L
A
K
E---
A
-
G
I
R
Q
F
L
D
I
G
T
G
I
P
T
SP
N
L
H
E
I
---------
A
-
Q
-
S
V
A-------
P
E
S
R
V
V
Y
V
D
N
D
P
I
V
L
T
L
S
Q
G
L
----
L
A
S
---------------------
T
P
------------------------
E
G
------------------
R
T
A
Y
V
E
A
D
M
L
--
D
--
P
--
A
S
I
L
D
A
P
E
L
R
D
T
-
L
D
L
T
R
P
V
A
L
T
V
I
A
I
V
H
F
V
-----
L
D
E
D
D
A
V
G
I
V
R
R
L
L
E
P
L
P
S
G
S
-
Y
L
-
A
M
-
S
-
I
G
T
A
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
40.90
15%
-43
- C2 -
2IP2
-
?
A:
[168-319]
-----------------------------------------------------------------------------------------------------------------------------------------------
G
R
S
F
V
D
V
G
G
G
S
G
E
--
L
T
K
A
I
---------
L
Q
A
-
E
---------
P
S
A
R
G
V
M
L
D
R
-
E
G
S
L
G
V
A
R
D
N
----
L
S
S
---------------------
L
L
A
-----------------------
G
E
------------------
R
V
S
L
V
G
G
D
M
L
--
Q
--
E
-------
V
---------
P
S
N
G
D
I
Y
L
L
S
R
I
I
G
D
L
-----
D
E
A
-
A
S
L
R
L
L
G
N
C
R
E
A
M
A
G
D
G
-
R
V
-
V
V
I
E
-
R
T
I
S
A
S
E
---
P
S
-----
P
M
S
V
L
-
W
---
D
-
V
H
L
F
----
M
A
C
A
G
R
-----
H
R
T
T
--
E
E
V
V
D
L
L
G
R
G
G
F
A
V
E
R
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
39.99
13%
-24
- C2 -
3LST
1
?
A:
[183-333]
--------------------------------------------------------------------------------------------------------------------------------------------
P
-
A
T
G
T
V
A
D
V
G
G
G
R
G
G
--
F
L
L
T
V
---------
L
R
E
-
H
---------
P
G
L
Q
G
V
L
L
D
R
-
A
E
V
V
A
R
H
R
L
D
----
A
P
D
---------------------
V
-------------------------
A
G
------------------
R
W
K
V
V
E
G
D
F
L
--
R
--
E
---------
V
--
P
H
------
A
D
V
H
V
L
K
R
I
L
H
N
W
-----
G
D
E
-
D
S
V
R
I
L
T
N
C
R
R
V
M
P
A
H
G
R
V
L
-
V
I
-
D
-
A
V
V
P
E
G
N
--
D
A
H
---
Q
S
K
E
M
D
F
-
M
---
M
-
L
-------
A
A
R
T
G
Q
-----
E
R
T
A
--
A
E
L
E
P
L
F
T
A
A
G
L
R
L
D
R
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------