@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0920c: (2016-04-27 )
MDAAQVIEPAHAGQDVDEAAVAARELSGAERALVGDLVRQARAEGVALTGPDGLLKALTKTVLEAALQEEMTEHLGYDRHAAAGRGSGNSRNGSRNKKVITDACGQVEIAVPRDRNGTFEPVIVGKRKRRVTDVDRVVLSLYAKGLTTGEIAAHFADVYGVSVSKDTISRITDRVIEEMQAWWSRPLEKVYAAVFIDAIMVKIRDGQVRNRPVYAAIGVDLDGHKDILGMWAGEGDGESAKFWLAVLTDLRNRGVKDIFFLVCDGLKGLPDSVSAAFPLATVQTCIIHLIRNTFRYASRKYWDKISVDLKPIYTAASAAEARLRYEEFAEKWGKPYPAITRLWDSAWEEFIPFLDYDVEIRRVPCSTNAIESLNARYRRAVRARGHFPNEQSALKTLYLVTRSLDPKGTGQTKWAVRWKPALNALAITFADRMPAAEER
Atome Classification :
(20 SA)
--------.......------------..10..----------......20........30..--------.....--------.40-----------........-50....---....60.......--.70........80........---90-.........100....--...110...-----....120..----.....130.---------------.-......140.---..--.....150-----.......------160.......170-----.......180..--------.....-------------190.......----------200....-----...210.....--..220--------.....---------------..-----------230.---.....-.240-------------..--.......250...-----....260..-----.....270-....----....280...--------....-290.....----------..300....-...310----.......320----------.....---..330------------.-...-----...340.......---350-----------------------....-....---360.....----..370....-...380.-----......----390.......-400---.......410------.......420.......430.......------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------M
D
A
A
Q
VI------------EPAHAG----------Q
D
V
D
E
A
A
V
A
A
R
ELSG
A
E
R
A
L
--------
V
G
D
L
V
--------
R
Q
A
-----------RAE
G
V
A
LT-G
P
D
G
L
L
---
K
A
L
T
K
T
V
L
E
A
A
L
Q
--
E
E
M
T
E
HLGYDRHAAAGRGSGN---S--RNGSRNK
K
V
I
TDACG
Q
--
V
E
I
A
VPRDR-----NGTFE
P
V
IV----GKRKRR
V
-
T
---------------
D
-
V
D
R
V
V
L
S
L
-
Y
---AK--GL
T
T
G
E
I
A
-----
A
H
F
A
D
VY------GVSV
S
K
D
T
I
S
R
I
T
-----
D
R
V
I
E
E
M
Q
A
W
W
S--------R
P
L
E
K
-------------
V
Y
A
A
V
F
I
D
A
I
----------
M
V
K
IRDG-----QVRNR
P
V
Y
A
A
I
--GVDLD--------GH
K
D
I
---------------
L
G
-----------
M
WAG---EGDGE-
S
A
---------------
K
F
--
W
L
A
V
L
T
D
L
R
NRG
V
-----
K
D
I
F
F
L
V
C
D-----GLKGLPD--SVSA----AF
P
L
A
T
V
Q
T
C
--------
I
I
H
L
-
I
R
N
T
F
R
Y
A
----------
S
R
K
Y
W
D
K
I
S
-VDL
K
P
I----YTAA
S
A
A
E
A
R
----------
L
R
Y
E
E
---
F
A
E
K
W------------G-KP
Y
-----
P
A
I
T
R
L
W
D
S
A
W
E
E
---
F
I
------------------------
P
FLD-YD
V
E
---
I
R
RVPCST----
N
A
I
E
S
L
N
A
R
-
Y
R
R
A
V
R
A-----RGHFP
N
----
E
Q
S
A
L
K
T
L
Y
L
-
V
TR---SLDPKGTGQ
T
------
K
W
A
V
R
WKPAL
N
A
L
A
I
T
FADRMPAAEER------------------------------------------------------------------------------------------------
38
Fugue
77.12
19%
-48
- C4 -
5FQE
24
?
A:
[28-607]
------TT
L
G
A
S
I
G
S
------------
T
D
F
H
Y
L
----------
Q
K
D
Y
D
E
I
K
K
L
N
L
N
T
W
N
E
V
A
W
--------
I
G
D
E
L
N
S
K
I
V
M
W
T
N
S
S
-----------
P
V
N
N
V
T
L
S
-
S
S
D
F
I
N
ENG
D
L
I
S
S
N
N
I
K
I
S
W
L
--
K
E
T
L
A
N
I
G
R
S
N
P
S
A
P
L
E
P
F
P
D
---
I
IH
N
S
G
S
L
N
I
E
K
N
K
I
A
S
A
W
--
I
N
I
K
I
P
R
N
A
KP
G
I
Y
N
G
S
I
E
V
T
A
D
----
E
L
E
K
S
Y
T
-
F
---------------
D
-
Y
S
F
E
V
L
N
L
-
V
QP-
L
P
--
S
E
T
N
T
Q
I
E
F
W
Q
H
P
Y
T
I
A
R
Y
Y
------
K
I
C
K
E
D
L
F
T
E
K
H
F
-----
K
Y
L
R
G
N
L
K
E
Y
R
N
--------
M
G
G
R
G
-------------
V
I
A
T
I
V
H
E
A
W
NHQSY
D
S
D
P
S
M
I
K
W
R
K
N
SYG
T
F
E
F
D
Y
S
H
F
D
K
W
I
--
Q
L
N
I
D
L
GILDPEK
G
F
G
Q
I
---------------
K
C
YSIVPWNN
R
I
Q
Y
F
N
E
---
A
T
N
K
E
-
E
A
I
N
P
T
PGS
D
L
W
I
N
I
W
T
Q
F
--
L
T
S
F
M
S
H
L
E
E
K
G
W
-----
F
N
I
T
Y
I
S
M
D
ERS
M
D
D
L
K
A
C
V
D
--
L
I
E
N
ITNN
S
Y
E
H
F
K
I
S
S
A
--------
M
D
Y
E
-
S
G
N
D
Y
S
F
L
----------
D
R
--
I
D
D
I
S
-
I
G
L
S
H
I
NHNS
D
D
M
K
N
M
A
T
H
R
----------
Q
E
L
G
L
---
L
T
T
I
Y
T
C
TGDYPSSFTI
S
-
D
P
S
-----
E
G
A
F
T
I
W
Y
S
L
Y
Q
N
TN
G
F
L
R
WSWDGWVENPLENVSYKYWEPGD
P
F
L
I
-
Y
P
A
E
KDS
I
G
K
T
F
Y
S
T
----
P
R
L
E
K
L
K
E
G
-
I
R
D
I
N
K
A
-----
K
Y
L
M
E
K
A
P
NL
K
N
S
I
E
N
L
I
Y
S
-
L
K
R
P
N
K
G
E
N
A
Y
G
S
A
V
A
AS
K
E
D
R
D
L
T
I
S
E
A
N
R
I
K
N
G
I
N
N
F
A
R
E
F
I
S
L
T
M
-------------------------------------------------------------------------------------------------
44
Fugue
64.50
19%
-40
- C4 -
4HNE
1
P4K2A_HUMAN
A:
[2-384]
--------------------------------------------
P
L
G
S
P
E
F
A
A
Q
A
Q
A
L
A
A
Q
A
A
--------
A
A
A
H
A
--------
A
Q
A
-----------
H
R
E
R
N
E
F
P
--
E
D
P
E
F
---
E
A
V
V
R
Q
A
E
L
A
I
E
R
--
C
I
F
P
E
R
I
--------------------
Y
Q
G
S
S
G
S
Y
F
V
K
D
P
Q
G
R
---
I
I
A
V
F
K
P
K
-----
N
E
E
P
Y
G
H
L
N
----
P
K
W
T
K
W
L
-
Q
---------------
K
-
F
G
R
D
C
L
V
L
-
N
---
Q
G
--
Y
L
S
E
A
G
A
S
-----
L
V
D
Q
K
L
E
------
L
N
I
V
P
R
T
K
V
V
Y
L
A
-----
S
E
T
F
N
Y
S
A
I
D
R
V
--------
K
S
R
G
K
-------------
R
L
A
--------------------
L
R
F
N
-----
R
I
G
L
P
P
K
V
G
S
F
--
Q
L
F
V
E
--------
G
Y
K
D
-------------------------------------------
A
---------------
D
Y
--
W
L
R
R
F
E
A
---------------------------
E
P
L
P
E
--
N
T
N
R
----
Q
L
L
L
Q
F
E
R
L
V
--------
V
L
D
Y
I
I
R
N
T
D
R
------------
G
N
D
N
W
-
L
I
K
-
Y
D
C
P
P
V
----
I
K
V
A
A
I
D
N
G
L
----------
A
F
P
L
K
---
H
P
D
S
W
--------------
R
A
Y
-----
P
-----
F
Y
W
A
W
L
P
---
Q
A
------------------------
K
-
V
P
-
F
S
Q
E
---
I
K
D
L
I
L
P
K
ISD
P
N
F
V
K
D
L
E
E
D
-
L
Y
E
L
F
K
K
DPGFD
R
G
Q
F
H
K
----
Q
I
A
V
M
R
G
Q
I
L
N
L
T
Q
---
A
L
K
D
----------------------
N
K
S
P
L
H
L
V
Q
M
P
P
V
I
V
E
T
------------------------------------------------------------------------------------------------
41
Fugue
63.09
18%
-54
* C4 *
5A07
3
KTR4_YEAST
A:
[40-434]
D
H
D
A
E
V
L
D
S
I
M
D
R
L
H
------------
E
P
L
Y
E
K
----------
D
T
F
D
P
N
E
V
L
A
E
N
K
Q
L
Y
E
E
F
L
L
QEISEPK
V
D
N
L
V
--------
R
S
G
DPLAG------
K
A
K
G
T
I
L
S
L
V
R
N
S
D
L
---
E
D
I
I
S
S
I
Q
Q
--
L
E
--
E
E
Y
N
K
N
F
G
Y
P
Y
T
F
L
N
-----------------
D
E
E
F
T
D
E
F
K
D
G
--
I
K
S
I
L
P
K
D
R
-----
V
V
E
F
G
T
I
------
G
P
D
N
W
N
M
-
P
---------------
D
S
I
D
R
E
R
Y
D
Q
-
E
---
M
D
--
K
M
S
K
E
N
I
-------
Q
Y
A
E
V
--------------------------
E
S
Y
H
N
M
C
R
F
Y
S
--------
K
E
----------------
F
Y
H
H
P
L
L
S
K
Y
----------
K
Y
V
W
R
-------
L
E
P
N
V
N
F
Y
C
K
I
--
N
Y
D
--------------
V
---------------
F
Q
-----------
F
M
N
K
-----
N
D
K
-
I
Y
---------------
G
F
--
V
L
N
L
Y
D
S
--
P
Q
T
I
-----
E
T
L
W
T
S
T
M
D
-----
F
V
E
E
H
P
N
YL
N
V
N
G
----
A
F
A
W
L
K
D
N
S
Q
--------
N
P
K
N
-
Y
D
Y
T
Q
G
Y
S
----------
T
C
H
F
W
T
N
F
E
I
V
D
L
D
F
L
----
R
S
E
P
Y
E
K
Y
M
Q
----------
Y
L
E
E
K
GGF
Y
Y
E
R
W
------------
G
D
A
P
V
-----
R
S
L
A
L
A
L
F
A
D
K
S
S
---
I
H
------------------------
W
F
R
D
---
I
G
---
Y
H
H
T
P
Y
T
N
----
C
P
T
C
P
A
D
S
D
-
R
C
N
G
N
C
V
-----
P
G
K
F
--------------------------------
T
------
P
W
S
D
L
D
N
Q
--
N
C
Q
A
T
W
I
R
H
S
M
S
E
E
E
L
E
MY----------------------------------------------------------------------------------------------
45
Fugue
55.58
13%
-38
- C5 -
4D10
-
CSN2_HUMAN
B:
[34-447]
----------------------------
V
D
L
E
N
----------
Q
Y
Y
N
S
K
A
L
K
E
D
D
P
K
A
A
L
S
S
F
--------
Q
K
V
L
E
--------
L
E
G
-----------
E
K
G
E
W
G
F
K
-
A
L
K
Q
M
I
---
K
I
N
F
K
L
T
N
F
P
E
M
M
--
N
R
Y
K
Q
L
L
T
Y
I
R
S
A
V
------
T
---
R
--
N
Y
S
E
K
S
I
N
S
I
L
D
Y
I
S
T
S
K
Q
M
D
L
L
Q
E
F
Y
-----
E
T
T
L
E
A
L
K
D
----
A
K
N
D
R
L
W
-
F
---------------
K
-
T
N
T
K
L
G
K
L
-
Y
---
L
E
--
R
E
E
Y
G
K
L
Q
-----
K
I
L
R
Q
L
H
Q
S
CQT
Q
L
L
E
I
Y
A
L
E
I
Q
M
Y
T
-----
A
Q
K
N
N
K
K
L
K
A
L
Y
--------
E
Q
S
L
H
-------------
I
K
S
A
I
P
H
P
L
I
----------
M
G
V
I
R
E
C
-----
G
G
K
M
H
L
R
E
G
E
F
--
E
K
A
H
T
--------
D
F
F
E
A
---------------
F
K
-----------
N
Y
D
E
---
S
G
S
P
R
-
R
T
---------------
T
C
L
K
Y
L
V
L
A
N
M
L
M
K
S
G
I
-----
N
P
F
D
S
Q
E
A
K
-----
P
Y
K
N
D
P
E
--
I
L
A
M
----
T
N
L
V
S
A
Y
Q
N
N
--------
D
I
T
E
-
F
E
K
I
L
K
T
N
----------
H
S
N
I
M
D
D
------
P
F
I
----
R
E
H
I
E
E
L
L
R
N
----------
I
R
T
Q
V
---
L
I
K
L
I
--------------
K
P
Y
-----
T
R
I
H
-------------
I
------------------------
P
F
I
S
-
K
E
L
N
---
I
-----
D
V
----
A
D
V
E
S
L
L
V
Q
-
C
I
L
D
N
T
I
-----
H
G
R
I
D
Q
----
V
N
Q
------
L
-
L
E
L
---
D
H
Q
K
R
G
G
A
R
Y
------
T
A
L
D
K
W
T
N
Q
L
N
S
L
N
Q
A
V
V
S
K
L
A
-----------------------------------------------------------------------------------------------------
36
Fugue
48.78
19%
-80
- C1 -
1AA7
-
M1_I34A1
A:
[1-158]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
L
-
T
---------------
E
-
V
E
T
Y
V
L
S
I
-
I
---
P
S
--
G
P
L
K
A
E
I
A
-----
Q
R
L
E
D
V
F
------
A
---
G
K
N
T
------------
D
L
E
V
L
M
E
W
L
K
T
RPIL---
S
P
L
T
K
-------------
G
I
L
G
-
F
V
F
T
L
----------
T
V
P
S
E
R
G
-----
L
Q
R
R
R
F
V
Q
N
A
L
NG
N
G
D
P
N
--------
N
M
D
K
A
---------------
V
K
-----------
L
Y
R
K
---
L
K
R
E
I
-
T
F
---------------
H
G
--
A
K
E
I
S
L
S
Y
S
A
G
A
L
-----
A
S
C
M
G
L
I
Y
N
-----
R
M
G
A
V
T
T
--
E
V
A
F
----
G
L
V
C
A
T
C
E
Q
I
--------
A
D
S
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
47.51
13%
-33
- C2 -
5E1J
6
TPC1_ARATH
A:
[32-686]
--------
Q
K
A
A
A
L
V
------------
D
L
A
E
D
G
I
G
L
P
V
E
I
L
DR
Y
Y
F
I
F
T
R
L
D
L
I
W
S
L
N
Y
F
A
L
L
--------
F
L
N
F
F
--------
E
Q
P
LWCEKNPKPSC
K
D
R
D
Y
Y
Y
L
-
G
E
L
P
Y
L
---
T
N
A
E
S
I
I
Y
E
V
I
T
L
--
A
I
L
L
V
H
T
F
F
P
I
S
Y
E
G
S
R
I
F
W
T
---
S
--
R
L
N
L
V
K
V
A
C
V
V
I
L
F
V
D
--
V
L
V
D
F
L
Y
F
R
-----
I
A
P
Y
V
R
V
I
I
F
I
L
S
I
R
E
L
R
D
T
-
L
---------------
V
-
L
L
S
G
M
L
G
T
-
Y
---
L
N
--
I
L
A
L
W
M
L
F
-----
L
L
F
A
S
W
I
------
A
F
V
M
F
E
D
T
Q
Q
G
L
T
VFTS
Y
G
A
T
L
Y
Q
M
F
I
L
F
T
TSNNPDVW
I
P
A
Y
K
S
SRW
S
S
V
F
F
V
L
Y
V
L
I
G
V
Y
F
V
T
N
L
----------
I
L
A
V
V
Y
D
-----
S
F
K
E
Q
L
A
K
Q
V
S
--
G
M
D
Q
M
--------
K
R
R
M
L
---------------
E
K
-----------
A
F
G
L
I
DS
D
K
N
G
E
I
D
K
---------------
N
Q
--
C
I
K
L
F
E
Q
L
T
N
Y
R
T
L
P
K
I
S
K
E
E
F
G
L
I
F
D
-----
E
L
D
D
T
R
D
--
F
K
I
N
----
K
D
E
F
A
D
L
C
Q
A
--------
I
A
L
R
-
F
Q
K
E
Y
H
S
A
L
S
Q
Q
L
R
A
F
V
R
S
P
N
F
G
Y
A
I
S
-
F
I
L
I
I
N
----
F
I
A
V
V
V
E
T
T
L
D
I
E
ESSAQ
K
P
W
Q
V
A
E
---
F
V
F
G
W
------------
I
-
Y
V
L
-----
E
M
A
L
K
I
Y
T
Y
G
F
E
N
---
Y
W
------------------------
R
E
G
A
-
N
R
F
D
---
F
L
V
T
W
V
I
V
----
I
G
E
T
A
T
F
I
T
P
F
S
N
G
E
W
I
-----
R
Y
L
L
L
A
----
R
M
L
R
L
I
R
L
L
M
-
N
V
Q
---
R
Y
R
A
F
I
A
T
F
I
------
T
L
I
P
S
L
M
P
Y
L
G
T
I
F
C
V
L
C
I
Y
C
S
I
G
V
Q
V
FGGLNK
K
L
F
E
T
ELA
E
D
D
Y
L
L
FNFND
Y
P
N
G
M
V
T
L
F
N
L
L
V
MGN
W
Q
V
W
M
E
S
Y
K
D
L
T
GTWWSI
T
Y
F
V
S
F
Y
V
I
TILL
L
L
N
L
V
V
A
F
V
L
E
A
F
F
T
E
L
D
L
E
E
E
E
K
34
HHSearch
43.72
24%
-34
- C3 -
1K78
-
PAX5_HUMAN
A:
[33-74]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
-
D
---------------
V
-
V
R
Q
R
I
V
E
L
-
A
---
H
Q
--
G
V
R
P
C
D
I
S
-----
R
----
Q
L
------
R
--
V
S
H
G
C
V
S
K
I
L
-----
G
R
Y
Y
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
43.50
20%
-16
- C3 -
1PDN
2
PRD_DROME
C:
[15-59]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
P
L
P
-
N
---------------
N
-
I
R
L
K
I
V
E
M
-
A
---
A
D
--
G
I
R
P
C
V
I
S
-----
R
Q
----
L
------
R
--
V
S
H
G
C
V
S
K
I
L
-----
N
R
Y
Q
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
42.63
20%
-6
- C3 -
4CXF
5
CNRH_CUPMC
A:
[143-182]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
V
I
V
L
T
-
A
---
I
V
--
G
M
S
Q
P
E
A
A
-----
A
V
----
L
------
G
--
L
S
V
K
A
V
E
G
R
I
-----
G
R
A
R
A
K
L
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
39.05
22%
-6
* C3 *
1OR7
-
RPOE_ECOLI
A:
[142-182]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
M
A
I
T
L
R
-
E
---
L
D
--
G
L
S
Y
E
E
I
A
-----
A
I
----
M
------
D
--
C
P
V
G
T
V
R
S
R
I
-----
F
R
A
R
E
A
I
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
38.31
12%
9
* C5 *
3HM6
19
X:
[72-638]
-IPFLDYK
V
Y
A
E
R
I
F
FPGHSPLHRDLG
V
P
E
S
R
R
----------
P
T
V
E
Q
G
L
G
Q
L
S
N
L
L
N
-
S
K
L
F
--------
L
T
K
F
I
--------
H
T
L
-----------
E
T
Q
R
T
F
S
A
-
R
D
R
A
Y
V
---
A
S
L
L
T
V
A
L
H
G
K
L
E
YF
T
D
I
L
R
T
L
L
S
D
L
V
A
Q
Y
V
A
K
N
P
K
LML
R
--
R
T
E
T
V
V
E
K
L
L
T
N
W
M
S
I
--
C
L
Y
T
F
V
R
D
S
-----
V
G
E
P
L
Y
M
L
F
----
R
G
I
K
H
Q
V
-
D
KGPVDSVTGKAKYTL
N
-
D
N
R
L
L
R
E
D
-
V
---
E
Y
--
R
P
L
T
L
N
A
L
-----
L
A
A
Q
G
V
P
------
V
K
V
L
D
C
D
T
I
S
Q
A
K
-----
E
K
M
L
D
Q
L
Y
K
G
V
P
--------
L
T
Q
R
P
-------------
D
P
R
T
L
D
V
E
W
R
SGVAG-----
H
L
I
L
S
D
E
-----
D
V
T
S
E
V
Q
G
L
W
R
--
R
L
N
T
L
--------
Q
H
Y
K
V
PDGATVALVPCGGIR
P
W
-----------
H
L
V
K
---
P
S
I
P
E
-
I
Y
---------------
L
T
--
R
L
L
S
M
K
G
T
L
Q
K
F
V
-----
D
D
L
F
Q
V
I
L
S
-----
T
S
R
P
V
P
L
--
A
V
K
Y
----
F
F
D
L
L
D
E
Q
A
Q
QHGISDQD
T
I
H
I
-
W
K
T
N
S
--
L
----------
P
L
R
F
W
I
N
I
I
-
K
N
P
Q
F
V
----
F
D
V
Q
T
S
D
N
M
D
----------
A
V
L
L
V
---
I
A
Q
T
F
------------
M
-
D
A
C
TLADS
P
I
N
K
L
L
Y
A
R
D
I
P
R
---
Y
K
------------------------
R
M
V
E
R
Y
Y
A
D
---
I
R
Q
T
V
P
A
S
------
D
Q
E
M
N
S
V
-
L
A
E
L
S
W
N
-----
Y
S
G
D
L
G
----
A
R
V
A
L
H
E
L
Y
K
-
Y
I
N
---
K
Y
------
Y
D
------
Q
I
I
T
A
L
E
E
D
G
T
A
Q
K
M
Q
L
G
Y
R
L
Q
Q
I
A
A
A
VE----------------------------------------------------------------------------------------------
35
HHSearch
36.22
18%
2
- C3 -
1HLV
2
CENPB_HUMAN
A:
[6-51]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
L
T
-
F
---------------
R
-
E
K
S
R
I
I
Q
E
-
V
---
E
E
N
P
D
L
R
K
G
E
I
A
-----
R
----
R
F
------
N
--
I
P
P
S
T
L
S
T
I
L
-----
K
N
K
R
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
35.08
10%
-40
- C3 -
2COB
-
A:
[15-56]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-
S
---------------
E
-
I
L
E
E
A
I
S
V
-
V
M
--
S
G
--
K
M
S
V
S
K
A
Q
-----
S
----
I
Y
------
G
--
I
P
H
S
T
L
E
Y
K
V
-----
K
E
R
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
34.30
19%
-8
- C3 -
2JN6
-
?
A:
[5-49]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Y
S
-
E
---------------
E
-
F
K
R
D
A
V
A
L
-
Y
---
E
N
SD
G
A
S
L
Q
Q
I
A
-----
N
----
D
L
------
G
--
I
N
R
V
T
L
K
N
W
I
-----
I
K
Y
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
33.31
24%
-1
- C3 -
2K27
-
PAX8_HUMAN
A:
[27-67]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
-
E
---------------
V
-
V
R
Q
R
I
V
D
L
-
A
---
H
Q
--
G
V
R
P
C
D
I
S
-----
R
----
Q
L
------
R
--
V
S
H
G
C
V
S
K
I
L
-----
G
R
Y
Y
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
33.30
24%
34
- C3 -
3J7A
-
?
U:
[24-61]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
W
L
K
Q
K
P
S
---------------
E
-
I
E
D
A
I
I
K
L
-
A
---
K
K
--
G
Q
T
P
S
Q
I
G
-----
A
T
L
R
D
N
Y
------
G
I
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
33.19
17%
1
- C3 -
2JRT
-
?
A:
[29-76]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
R
R
W
V
-
A
---------------
S
-
R
K
A
A
V
V
K
A
-
V
---
I
H
G-
L
I
T
E
R
E
A
L
-----
D
----
R
Y
------
S
--
L
S
E
E
E
F
A
L
W
R
-----
S
A
V
A
A
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
33.02
7%
5
- C3 -
1U78
-
TC3A_CAEEL
A:
[6-47]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
S
-
D
---------------
T
-
E
R
A
Q
L
D
V
M
-
K
---
L
L
--
N
V
S
L
H
E
M
S
-----
R
K
----
I
------
S
--
R
S
R
H
C
I
R
V
Y
L
-----
K
D
P
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
32.93
15%
11
- C3 -
2LFW
-
?
A:
[100-140]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
L
L
L
T
A
---
M
E
--
G
F
S
P
E
D
A
A
-----
Y
L
----
I
------
E
--
V
D
T
S
E
V
E
T
L
V
-----
T
E
A
L
A
E
I
E
K
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
32.34
13%
-9
- C3 -
1IUF
-
ABP1_SCHPO
A:
[8-58]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
-
E
---------------
H
-
E
K
R
A
L
R
H
Y
-
F
FQL
Q
N
--
R
S
G
Q
Q
D
L
I
-----
E
W
F
R
E
K
F
------
G
K
D
I
S
Q
P
S
V
S
Q
I
L
-----
S
S
K
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------