@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2353c: (2016-05-10 )
MPGRFRNFGSQNLGSGNIGSTNVGSGNIGSTNVGSGNIGDTNFGNGNNGNFNFGSGNTGSNNIGFGNTGSGNFGFGNTGNNNIGIGLTGDGQIGIGGLNSGSGNIGFGNSGTGNVGLFNSGTGNVGFGNSGTANTGFGNAGNVNTGFWNGGSTNTGLANAGAGNTGFFDAGNYNFGSLNAGNINSSFGNSGDGNSGFLNAGDVNSGVGNAGDVNTGLGNSGNINTGGFNPGTLNTGFFSAMTQAGPNSGFFNAGTGNSGFGHNDPAGSGNSGIQNSGFGNSGYVNTSTTSMFGGNSGVLNTGYGNSGFYNAAVNNTGIFVTGVMSSGFFNFGTGNSGLLVSGNGLSGFFKNLFG
Atome Classification :
(20 SA)
--------------------------------------.........10........20........30........40...-------.....50........60........70........80........90........100.......110.......120....---..------.130----.....-..140.......150.......160..--.....170.......180.---------------......190.......200...--.----...210.....------..220.......-------------230..--.....240--.......250.......260.....-..270.....----..280.......290.....--------.--.300.......310...-....---320.--------......330-.......340.......350..-----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------MPGRFRNFGSQNLGSGNIGSTNVGSGNIGSTNVGSGNIGDTNFG-------NGNNG
N
F
NFGSGNTGSNNIGFGNTGSGNFGFGNTGNN
N
I
G
I
G
L
TGDG
Q
I
G
I
GGLNSGSGNIGFGNSGTGNVGLFNSGTGNVG---FG------NSGT----ANTGF-GNAGNVNTGFWNGGSTNTGLANAGAGN--TGFFDAGNYNFGSLNAGNI---------------NSSFGNSGDGNSG
F
L
NAGDVNS--G----VGNAGDVNTGL------GNSGNINTGGFN-------------PGTL
N
--
T
G
F
F
S
A
M
T
--QAGPNSGFFNAGTGNSGFGHNDPAG-SGNSGIQNSG----FGNS
G
Y
V
NT
S
T
T
S
MFGGNS
G
--------
V
--
L
NTGYGNSG
F
Y
N
A
A
VNN-T
G
I
F
---
V
T
GV--------MSS
G
F
F
NFG-TGNS
G
L
L
V
SGN
G
L
S
G
F
F
K
N
LFG-----------
19
Fugue
80.56
16%
-21
- C3 -
4FDW
19
?
A:
[21-401]
----------------------------------------
A
S
L
E
D
F
S
I
E
Q
L
P
A
K
T
I
Y
A
L
G
E
N
I
D
L
T
G
L
N
V
T
G
K
Y
D
D
G
K
Q
R
P
V
K
V
T
SEQI
S
G
F
S
S
S
V
P
V
D
K
Q
E
V
T
I
T
I
E
G
K
Q
K
S
F
S
V
H
I
S
P
V
R
V
E
N
G
V
L
T
E
I
L
K
G
Y
N
E
I
I
L
P
N
S
V
K
S
I
P
K
D
A
F
R
N
S
Q
I
A
K
V
V
L
-
N
E
G
L
K
S
I
G
D
MA
F
F
------
N
S
T
V
----
Q
E
I
V
F
P
S
T
L
E
Q
L
K
E
D
I
F
Y
Y
C
Y
-
N
L
K
K
A
D
L
S
K
T
K
--
I
T
K
L
P
A
S
T
F
V
Y
A
G
I
E
E
V
L
L
---------------
P
V
T
L
K
E
I
G
--
S
Q
A
F
L
K
T
S
Q
L
K
T
-------
I
E
I
P
E
N
V
S
T
I
--------
G
Q
E
A
F
R
E
S
G
I
T
-------------
T
V
K
L
P
--
N
G
V
T
N
I
A
S
--
R
A
F
Y
Y
C
P
E
L
A
E
V
T
T
Y
G
S
T
F
N
D
D
P
E
A
M
I
H
P
Y
C
L
E
G
C
P
KLA
R
F
E
I
P
E
S
I
R
I
L
G
Q
G
L
L
G
G
N
R
K
--------
V
T
Q
L
T
I
P
A
N
V
T
Q
I
N
F
S
A
F
N
N
-
T
G
I
K
---
E
V
K
V
EGTTPPQV
F
E
K
V
W
Y
G
F
P
-
D
D
I
T
V
I
R
V
P
A
E
S
V
E
K
Y
K
N
A
N
-
G
W
R
D
F
T
NKITTF
20
Fugue
75.36
16%
-10
* C5 *
3JCM
-
?
B:
[22-465]
N
E
S
T
A
D
I
L
K
Q
L
P
H
E
R
L
Q
A
V
L
E
K
I
P
E
E
D
L
E
V
R
R
L
L
S
I
L
K
K
P
E
V
V
E
N
E
D
V
Q
Q
R
R
I
R
L
A
E
I
L
M
V
D
E
I
D
L
E
N
I
N
N
D
F
F
T
P
A
T
S
E
L
I
-------
F
A
R
R
F
L
I
N
Y
S
L
E
R
S
R
K
R
L
Q
K
E
M
E
R
H
Q
K
F
N
T
R
Q
E
L
L
S
R
R
T
E
L
Q
R
M
A
N
L
E
L
A
G
S
Q
L
V
S
T
K
P
I
S
A
V
S
L
S
T
D
D
M
V
V
A
T
G
S
W
A
G
D
L
Q
---
V
L
------
N
S
Q
T
LQPL
T
Q
K
L
D
-
S
H
V
G
K
I
G
A
I
D
W
H
P
D
S
N
N
Q
M
I
S
C
A
E
D
G
L
--
I
K
N
F
Q
Y
S
N
E
E
G
G
L
R
L
L
G
D
L
V
GHERRIS
D
V
K
Y
HPS
G
K
F
I
G
S
A
S
H
D
M
T
W
R
L
W
D
A
S
T
H
Q
--
E
----
L
L
L
Q
E
G
H
D
K
G
V
F
S
L
S
F
Q
C
D
G
S
L
V
C
S
G
G
M
D
S
L
S
M
L
W
D
IRSGSK
V
M
T
L
A
--
G
H
S
K
P
I
Y
T
--
V
A
W
S
P
N
G
Y
Q
V
A
T
G
G
G
D
G
I
I
N
V
W
D
I
R
-
K
R
D
E
G
Q
L
N
Q
I
----
L
A
H
R
N
I
V
T
Q
V
R
F
S
K
E
D
G
G
K
K
--------
L
--
V
S
C
G
Y
D
N
--
L
I
N
V
Y
S
S
D
-
T
W
L
K
---
M
G
S
L
A
G------
H
T
D
K
I
I
S
L
D
I
S
N
N
S
H
F
L
V
S
G
-
G
W
D
R
S
I
K
-
L
W
N
-----------
21
Fugue
58.23
19%
10
- C5 -
4AUI
6
?
A:
[20-327]
-----------------------------------------
D
V
T
L
Y
G
T
I
K
A
G
V
E
T
S
R
S
V
A
H
H
G
A
Q
A
D
R
V
K
T
A
T
E
I
A
D
L
--------------------------
G
S
K
I
G
F
K
------------
G
Q
E
D
L
G
N
G
L
K
A
I
W
Q
L
E
Q
K
A
Y
V
S
G
T
------
D
T
G
W
G
N
R
Q
S
F
I
G
L
K
G
G
F
G
---
K
V
------
R
V
G
R
----
L
N
N
I
L
-
K
D
T
G
N
F
N
P
--
W
E
G
K
S
Y
Y
S
G
L
S
N
I
A
Q
P
E
ER
H
V
S
V
R
Y
D
S
P
E
F
A
G
F
S
G
S
V
Q
---------------
Y
V
P
N
D
N
S
G
K
N
R
S
E
S
Y
H
A
G
F
N
Y
K
--
N
DG
F
F
V
Q
Y
A
G
S
Y
K
R
H
N
------
Y
T
T
E
K
H
Q
V
H
R
L
V
-------------
G
G
Y
D
H
--
D
A
L
Y
A
S
V
A
--
V
Q
Q
Q
D
A
K
L
T
W
R
D
D
-
N
S
H
N
S
Q
T
E
V
A
T
-
T
V
A
Y
R
---------
F
G
N
V
----
T
P
R
V
S
Y
A
H
G
F
K
G
--------
S
--
V
Y
D
A
D
H
D
N
T
Y
D
Q
V
V
V
G
A
-
E
Y
D
F
SKR
T
S
A
L
--------
V
S
A
G
W
L
Q
K
G
-
K
G
A
E
K
F
V
A
T
V
G
G
V
G
L
R
H
K
F
--------------
25
Fugue
52.30
13%
5
- C2 -
4TXD
1
?
A:
[21-369]
-------------------------------------------
K
R
D
V
L
A
E
L
G
L
G
D
L
R
P
Y
L
R
S
I
G
D
K
D
R
I
F
P
K
A
H
R
I
E
V
V
F
L
V
-------
R
A
A
N
-
Y
L
L
L
R
T
E
G
A
G
T
I
N
M
T
T
L
E
Y
S
G
G
A
M
E
V
P
V
I
-
Q
P
Q
K
L
M
A
V
T
R
R
Q
M
L
Q
L
L
R
E
Y
R
D
S
L
D
E
V
S
K
R
W
L
V
Q
E
V
I
G
K
A
K
D
L
G
F
K
K
---
V
S
------
E
E
W
N
----
C
T
I
Q
G
-
M
D
G
F
C
P
H
C
T
I
F
--
G
A
A
L
T
E
Q
H
N
E
K
F
G
G
--
L
S
I
G
I
K
T
R
V
R
F
D
P
A
F
A
T
Q
R
---------------
R
I
T
P
E
T
H
N
K
V
T
E
G
H
L
S
M
--
T
G
Q
--
A
----
L
F
S
E
V
H
V
E
P
G
T
------
V
F
I
G
R
A
E
L
V
D
L
T
-------------
E
P
E
L
V
--
A
T
L
Y
S
L
A
T
L
R
E
L
G
G
R
S
G
I
Y
------------------
G
T
V
R
V
E
I
L
G
----
V
K
A
G
K
Y
A
S
T
T
A
Y
D
L
A
A
E
N
A
G
KG
Y
E
E
V
K
K
N
--
L
K
E
R
L
E
K
L
G
F
T
P
--
V
D
N
-
S
K
L
L
---
A
A
V
D
--------
H
K
D
P
N
G
L
F
K
-
D
L
W
R
S
S
I
D
F
A
E
K
M
V
K
W
V
E
E
L
K
G
GG---------
1
PsiBlast_PDB
38.96
28%
-28
- C6 -
1KZH
3
PFP_BORBU
A:
[74-174]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
G
I
I
L
S
G
G
P
A
-------------
P
G
G
H
N
V
I
S
G
V
F
D
A
I
K
--
K
F
N
P
N
S
K
L
F
G
F
K
G
G
P
L
G
L
L
E
N
D
K
I
E
-
L
T
E
S
L
I
N
S
------
Y
R
N
T
G
G
F
D
I
V
S
S
----
G
R
T
K
--------
I
--
E
T
E
E
H
Y
N
K
A
L
F
V
A
K
E
N
N
L
N
A
I
I
---
I
I
G
----------------------------------------------------
2
PsiBlast_PDB
36.74
28%
-20
- C6 -
2F48
1
PFP_BORBU
A:
[74-174]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
G
I
I
L
S
G
G
P
A
-------------
P
G
G
H
N
V
I
S
G
V
F
D
A
I
K
--
K
F
N
P
N
S
K
L
F
G
F
K
G
G
P
L
G
L
L
E
N
D
K
I
E
-
L
T
E
S
L
I
N
S
------
Y
R
N
T
G
G
F
D
I
V
S
S
----
G
R
T
K
--------
I
--
E
T
E
E
H
Y
N
K
A
L
F
V
A
K
E
N
N
L
N
A
I
I
---
I
I
G
----------------------------------------------------
9
PsiBlast_PDB
35.53
23%
-1
- C4 -
2YO3
-
GCN4_YEAST
A:
[70-199]
----------------------------------------------------------------------------------------------------------------
T
G
S
T
K
Y
F
K
T
N
T
D
G
A
D
A
N
A
Q
G
A
D
S
V
A
I
G
S
G
S
I
A
A
A
E
N
S
V
A
L
G
T
N
S
V
A
D
----
E
A
N
T
V
S
V
G
-------------------
S
S
T
Q
Q
-
R
R
I
T
N
V
A
A
G
V
N
N
T
D
A
V
N
V
A
Q
L
K
A
S
---------
E
A
G
S
V
R
Y
E
T
N
A
D
G
S
V
---------------
N
Y
S
V
L
N
L
G
D
G
S
G
G
T
T
R
I
G
N
V
S
A
--
A
----
V
N
D
T
D
A
V
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
33.77
29%
-92
- C6 -
2VXR
-
A:
[51-102]
---------------------------------------------------------------
N
A
I
L
S
L
S
Y
R
G
G
R
L
I
D
S
S
----------
G
Y
G
A
T
M
N
V
G
S
------
D
V
I
F
N
D
I
G
N
G
Q
F
K
L
N
N
S
E
N
S
N
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
31.56
30%
-33
- C4 -
3VZW
2
?
X:
[85-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
S
G
W
G
N
--
R
Q
S
F
I
G
L
K
G
G
F
G
T
V
R
A
G
N
L
---------------
N
T
V
L
K
D
S
G
D
N
V
N
A
W
E
S
G
S
N
T
E
D
VL
G
----
L
G
T
I
G
R
V
E
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
31.41
30%
-37
- C4 -
3A2S
2
?
X:
[85-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
S
G
W
G
N
--
R
Q
S
F
I
G
L
K
G
G
F
G
T
V
R
A
G
N
L
---------------
N
T
V
L
K
D
S
G
D
N
V
N
A
W
E
S
G
S
N
T
E
D
VL
G
----
L
G
T
I
G
R
V
E
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
30.92
30%
-33
- C4 -
3VZU
1
?
X:
[85-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
S
G
W
G
N
--
R
Q
S
F
I
G
L
K
G
G
F
G
T
V
R
A
G
N
L
---------------
N
T
V
L
K
D
S
G
D
N
V
N
A
W
E
S
G
S
N
T
E
D
VL
G
----
L
G
T
I
G
R
V
E
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
30.77
30%
-37
- C4 -
3VY8
1
?
X:
[85-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
S
G
W
G
N
--
R
Q
S
F
I
G
L
K
G
G
F
G
T
V
R
A
G
N
L
---------------
N
T
V
L
K
D
S
G
D
N
V
N
A
W
E
S
G
S
N
T
E
D
VL
G
----
L
G
T
I
G
R
V
E
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
30.63
30%
-38
- C4 -
3VZT
2
?
X:
[85-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
S
G
W
G
N
--
R
Q
S
F
I
G
L
K
G
G
F
G
T
V
R
A
G
N
L
---------------
N
T
V
L
K
D
S
G
D
N
V
N
A
W
E
S
G
S
N
T
E
D
VL
G
----
L
G
T
I
G
R
V
E
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
29.34
30%
-12
- C4 -
3VY9
3
?
X:
[85-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
S
G
W
G
N
--
R
Q
S
F
I
G
L
K
G
G
F
G
T
V
R
A
G
N
L
---------------
N
T
V
L
K
D
S
G
D
N
V
N
A
W
E
S
G
S
N
T
E
D
VL
G
----
L
G
T
I
G
R
V
E
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
29.17
32%
-90
- C6 -
3V4E
3
ATRF2_STAAC
A:
[107-149]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
N
C
G
F
Y
T
A
-
T
H
P
L
N
F
H
H
------------
R
N
E
G
----
F
E
K
A
G
P
I
H
I
G
S
N
T
W
F
G
G
H
V
A
--------
V
--
L
-------------------------------------------------------------------------------
3
PsiBlast_PDB
29.08
32%
-99
- C6 -
4EGG
3
ATRF2_STAAC
A:
[104-146]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
N
C
G
F
Y
T
A
-
T
H
P
L
N
F
H
H
------------
R
N
E
G
----
F
E
K
A
G
P
I
H
I
G
S
N
T
W
F
G
G
H
V
A
--------
V
--
L
-------------------------------------------------------------------------------
22
Fugue
28.05
15%
-120
- C4 -
1F93
-
HNF1A_MOUSE
H:
[5-30]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
Q
L
Q
--
T
E
L
L
A
A
L
L
--
E
S
G
L
S
K
E
A
L
I
Q
A
L
------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
27.15
32%
-86
- C6 -
4DCL
-
ATRF2_STAAC
A:
[104-146]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
N
C
G
F
Y
T
A
-
T
H
P
L
N
F
H
H
------------
R
N
E
G
----
F
E
K
A
G
P
I
H
I
G
S
N
T
W
F
G
G
H
V
A
--------
V
--
L
-------------------------------------------------------------------------------
5
PsiBlast_PDB
26.47
32%
-87
- C6 -
3FTT
-
ATRF2_STAAC
A:
[104-146]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
N
C
G
F
Y
T
A
-
T
H
P
L
N
F
H
H
------------
R
N
E
G
----
F
E
K
A
G
P
I
H
I
G
S
N
T
W
F
G
G
H
V
A
--------
V
--
L
-------------------------------------------------------------------------------
8
PsiBlast_PDB
26.06
36%
-141
* C6 *
3HRD
2
NDMMS_EUBBA
B:
[7-52]
------------------------------------------------------------------------------------------------------------------------------------------
G
V
G
S
M
W
Y
G
I
G
N
T
G
L
P
N
P
A
A
A
F
V
E
I
H
G
D
G
S
A
N
V
M
---
F
G
AADIGQ
G
S
G
T
----
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------