@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0084: (2015-12-21 )
MAELSTENLAQGQTTTEQTSEFASLLLQEFKPKTERAREAVETAVRTLAEHALEQTSLISNDAIKSIESIIAALDAKLTAQVNLIMHHADFQQLESAWRGLHYLVNNTETDEQLKIRVLNISKPELHKTLKKFKGTTWDQSPIFKKLYEEEYGQFGGEPYGCLVGDYYFDQSPPDVELLGEMAKISAAMHAPFISAASPTVMGMGSWQELSNPRDLTKIFTTPEYAGWRSLRESEDSRYIGLTMPRFLARLPYGAKTDPVEEFAFEEETDGADSSKYAWANSAYAMAVNINRSFKLYGWCSRIRGVESGGEVQGLPAHTFPTDDGGVDMKCPTEIAISDRREAELAKNGFMPLLHKKNTDFAAFIGAQSLQKPAEYDDPDATANANLAARLPYLFATCRFAHYLKCIVRDKIGSFKEKDEMQRWLQDWILNYVDGDPAHSTETTKAQHPLAAAEVVVEEVEGNPGYYNSKFFLRPHYQLEGLTVSLRLVSKLPSAKEA
Atome Classification :
(17 SA)
------.........10........20........30........40........50........60---.--.......70..---....-..80........90........-----100.......110........-----120...----....130.------......--140......--------.150.......160.....--..170-.........180----...--.....190.......200.......210.......220.......230.......240.......250.......260-.-.---......270.......280.......290.......300.......310.......--320.......330.......-340.......350---.--.......360-------....--....370-------.......380.....-----------..390...---....400....----...410---------------.---.---.....--420.......430----........440---.......450..--.....460..-----....----...470....-...480...----..-..490......---------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------MAELS
T
E
N
LAQGQT
T
T
E
Q
T
S
E
F
A
S
L
L
L
Q
EFKP
K
T
E
R
A
R
E
A
V
E
T
A
V
R
T
L
A
E
H
A
L
E
Q
T
SLI
S
N
---
D
--
A
I
K
S
I
E
S
I
I
A
A
---
L
D
A
K
-
L
T
A
Q
V
N
L
I
M
HHA
D
F
Q
Q
L
E
S
A
W
R
-----
G
L
H
Y
L
VNNTETD-
E
Q
L
K
I
R
V
L
-----NIS
K
P
E
----
L
H
K
T
L
K
K
F------KGTTWD--Q
S
P
I
F
K
K
L
Y
--------
E
E
E
Y
G
QFGGEP
Y
G
C
L
V
G
D
Y--YFD---QSPP
D
V
E
L
L
G
E
-----
M
A
K
--
I
S
A
A
MHAPFISAASP
T
V
M
GMG
S
W
Q
ELSNP
R
D
L
T
K
IFTTPE
Y
A
G
W
R
S
L
RESEDS
R
Y
I
GL
T
M
P
R
F
L
A
RLPYGAKTD
P
V
E
--
E
-F---AFEEETDGADSS
K
Y
A
WANS
A
Y
A
M
A
V
NINR
S
F
K
L
Y
G
W
C
S
R
IRGVESGGEVQGLPAHT--FPTDDGGVDMKCP
T
E
I
AISD-R
R
E
A
E
L
A
KNGF
M
----
P
--
L
LHKKNT
D
F
--------
A
A
F
I
--
G
A
Q
S
LQK-------PAEYDDPDATANA
N
L
-----------
A
A
R
L
P
Y
L
F
---
A
T
C
R
F
A
H
Y
L
K
C
----
I
V
R
D
KI---------------G---S---F
K
E
K
D
--
E
M
Q
R
W
L
Q
D
W
I
L
N
-----YVDGDPAHSTE---TTKAQHP
L
A
A
A
E
--
V
V
V
E
EV--EG-----NPGY----YNS
K
F
F
LRPH-
Y
Q
LE
G
L
T
V
S
----
L
R
-
L
V
S
KLPSAKEA---------
13
Fugue
94.14
30%
-70
- C2 -
3J9O
-
?
B:
[79-505]
-----------------------------------------------------------------------------------
V
---
I
D
K
L
-
I
D
L
Q
V
N
S
I
I
S
N
D
E
F
R
A
L
E
Q
E
W
L
-----
K
V
Q
E
V
C
Q
--
E
D
Y
-
D
N
V
E
V
S
I
L
-----
D
V
K
K
E
E
----
L
Q
Y
D
F
E
R
-------
N
L
Y
D
I
S
--
S
S
D
F
F
K
K
V
Y
--------
V
S
E
F
D
Q
Y
G
G
E
P
Y
G
A
I
L
G
L
Y
--
N
F
E
---
N
T
T
N
D
I
I
W
L
T
G
-----
M
G
M
--
V
A
K
N
S
H
A
P
F
I
A
S
I
D
K
S
F
F
G
V
K
D
L
S
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I
T
H
I
K
S
F
E
A
L
L
E
H
P
R
Y
K
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W
N
D
F
R
N
L
D
V
A
A
Y
I
G
L
T
V
G
D
F
M
L
R
Q
P
Y
N
P
E
N
N
P
V
Q
--
Y
-
K
LME
G
F
N
E
F
V
D
Y
D
K
N
E
S
Y
L
W
G
P
A
S
I
H
L
V
K
N
M
M
R
S
Y
D
K
T
R
W
F
Q
Y
I
R
G
V
E
S
G
G
Y
V
K
N
L
V
A
C
V
--
Y
D
N
K
-
G
I
L
E
T
K
S
P
L
N
V
L
F
A
D
-
Y
M
E
L
S
L
A
N
I
G
L
I
----
P
--
F
V
S
E
K
G
T
S
N
--------
A
C
F
F
--
S
V
N
S
A
K
K
-------
V
E
E
F
V
D
G
F
D
S
A
N
S
R
L
-----------
I
A
N
L
S
Y
T
M
---
C
I
S
R
I
S
H
Y
I
K
C
----
V
I
R
D
K
I
---------------
G
---
S
---
I
V
D
V
E
--
S
I
Q
K
I
L
S
D
W
I
S
E
-----
F
V
T
-
T
V
Y
Q
P
T
P
---
L
E
M
A
R
Y
P
F
R
N
V
S
--
I
E
V
K
T
I
--
P
G
-----
K
P
G
W
----
Y
S
C
K
I
N
V
I
P
H
-
I
Q
F
E
G
M
N
T
T
----
M
T
-
I
D
T
R
L
E
P
E
L
F
G
TNN------
1
PsiBlast_PDB
92.95
31%
-71
- C2 -
3J9O
-
?
B:
[79-496]
-----------------------------------------------------------------------------------
V
---
I
D
K
L
-
I
D
L
Q
V
N
S
I
I
S
N
D
E
F
R
A
L
E
Q
E
W
L
-----
K
V
Q
E
V
C
Q
--
E
D
Y
-
D
N
V
E
V
S
I
L
-----
D
V
K
K
E
E
----
L
Q
Y
---
D
F
------
E
R
N
L
Y
D
IS
S
S
D
F
F
K
K
V
Y
--------
V
S
E
F
D
Q
Y
G
G
E
P
Y
G
A
I
L
G
L
Y
--
N
F
E
---
N
T
T
N
D
I
I
W
L
T
G
-----
M
G
M
--
V
A
K
N
S
H
A
P
F
I
A
S
I
D
K
S
F
F
G
V
K
D
L
S
E
I
T
H
I
K
S
F
E
A
L
L
E
H
P
R
Y
K
E
W
N
D
F
R
N
L
D
V
A
A
Y
I
G
L
T
V
G
D
F
M
L
R
Q
P
Y
N
P
E
N
N
P
V
Q
--
Y
-
K
LME
G
F
N
E
F
V
D
Y
D
K
N
E
S
Y
L
W
G
P
A
S
I
H
L
V
K
N
M
M
R
S
Y
D
K
T
R
W
F
Q
Y
I
R
G
V
E
S
G
G
Y
V
K
N
L
V
A
C
V
--
Y
D
-
N
K
G
I
L
E
T
K
S
P
L
N
V
L
F
A
D
-
Y
M
E
L
S
L
A
N
I
G
L
I
----
P
--
F
V
S
E
K
G
T
S
N
--------
A
C
F
F
--
S
V
N
S
A
K
K
-------
V
E
E
F
V
D
G
F
D
S
A
N
S
R
L
-----------
I
A
N
L
S
Y
T
M
---
C
I
S
R
I
S
H
Y
I
K
C
----
V
I
R
D
K
I
---------------
G
---
S
---
I
V
D
V
E
--
S
I
Q
K
I
L
S
D
W
I
S
E
-----
F
V
-
T
T
V
Y
Q
P
T
P
---
L
E
M
A
R
Y
P
F
R
N
V
S
--
I
E
V
K
T
I
--
P
G
-----
K
P
G
W
----
Y
S
C
K
I
N
V
I
P
H
-
I
Q
F
E
G
M
N
T
T
----
M
T
-
I
D
T
R
L
E
P
E
L
F
G
---------
3
HHSearch
92.91
29%
-74
- C2 -
3J9O
-
?
B:
[79-500]
-----------------------------------------------------------------------------------
V
---
I
D
K
L
-
I
D
L
Q
V
N
S
I
I
S
N
D
E
F
R
A
L
E
Q
E
W
L
-----
K
V
Q
E
V
C
Q
E
--
D
Y
-
D
N
V
E
V
S
I
L
-----
D
V
K
K
E
E
----
L
Q
Y
D
F
E
R
N
-------
L
Y
D
I
S
--
S
S
D
F
F
K
K
V
Y
--------
V
S
E
F
D
Q
Y
G
G
E
P
Y
G
A
I
L
G
L
Y
--
N
F
E
---
N
T
T
N
D
I
I
W
L
T
G
-----
M
G
M
--
V
A
K
N
S
H
A
P
F
I
A
S
I
D
K
S
F
F
G
V
K
D
L
S
E
I
T
H
I
K
S
F
E
A
L
L
E
H
P
R
Y
K
E
W
N
D
F
R
N
L
D
V
A
A
Y
I
G
L
T
V
G
D
F
M
L
R
Q
P
Y
N
P
E
N
N
P
V
Q
YK
L
-
M
E--
G
F
N
E
F
V
D
Y
D
K
N
E
S
Y
L
W
G
P
A
S
I
H
L
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K
N
M
M
R
S
Y
D
K
T
R
W
F
Q
Y
I
R
G
V
E
S
G
G
Y
V
K
N
L
V
A
C
V
--
Y
D
N
-
K
G
I
L
E
T
K
S
P
L
N
V
L
F
A
D
-
Y
M
E
L
S
L
A
N
I
G
L
I
----
P
--
F
V
S
E
K
G
T
S
N
--------
A
C
F
F
--
S
V
N
S
A
K
K
-------
V
E
E
F
V
D
G
F
D
S
A
N
S
R
L
-----------
I
A
N
L
S
Y
T
M
---
C
I
S
R
I
S
H
Y
I
K
C
----
V
I
R
D
K
I
---------------
G
---
S
---
I
V
D
V
E
--
S
I
Q
K
I
L
S
D
W
I
S
E
-----
F
V
T
T
V
Y
Q
-
P
T
P
---
L
E
M
A
R
Y
P
F
R
N
V
S
--
I
E
V
K
T
I
--
P
G
-----
K
P
G
W
----
Y
S
C
K
I
N
V
I
P
H
-
I
Q
F
E
G
M
N
T
T
----
M
T
-
I
D
T
R
L
E
P
E
L
F
G
---------
14
Fugue
58.28
18%
2
- C3 -
4BIJ
-
TERL_BPT7
A:
[1-476]
---------
M
S
T
Q
S
N
R
N
A
L
V
V
A
Q
L
K
G
D
F
V
A
F
L
F
V
L
W
K
A
L
N
L
P
V
P
T
K
C
Q
I
D
M
A
K
V
L
A
N
G
D
N
K
------------------------------------
K
F
I
L
Q
A
--
F
R
G
I
G
K
S
F
I
-----
T
C
A
F
V
V
W
S
L
W
R
D
-
P
Q
L
K
I
L
I
V
-----
S
A
S
K
E
R
----
A
D
A
N
S
I
F
I
------
K
N
I
I
-
D
--
L
L
P
F
L
S
E
L
---------
K
P
R
P
G
Q
R
D
S
-
V
I
S
F
D
V
G
P
A
--
N
P
D
---
H
S
P
S
-
V
K
S
V
G
I
-----
T
G
Q
--
L
T
G
S
-
R
A
D
I
I
I
A
D
D
------------------
V
E
I
P
S
N
S
A
T
M
G
A
R
E
K
L
W
T
L
V
Q
E
F
A
A
L
L
K
P
L
P
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V
I
Y
L
G
T
P
Q
T
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M
--
T
-
L
---
Y
K
E
L
E
D
N
R
G
Y
T
T
I
I
W
P
A
L
Y
P
R
T
R
E
E
N
L
Y
Y
S
Q
R
L
A
M
--
L
R
A
E
Y
D
E
N
P
E
A
L
A
G
T
P
T
D
P
--
V
R
F
D
R
D
D
L
R
------------
E
R
E
L
E
Y
G
K
A
G
F
T
----
L
Q
F
M
L
N
P
N
L
S
D
A
EKYPLRLR
D
A
I
V
--
A
A
L
D
L
E
K
AM
H
Y
Q
W
L
P
N
R
Q
N
I
I
E
D
L
P
N
V
G
L
-----------
K
G
D
D
L
H
T
Y
HDC
S
N
N
S
G
Q
Y
Q
Q
K
I
----
L
V
I
D
P
S
---------------
G
---
R
---
G
K
D
E
T
G
Y
A
V
L
Y
T
L
N
G
Y
I
Y
L
MEAGG
F
R
D
G
Y
S
D
K
T
L
E
---
L
L
A
K
K
A
K
Q
W
G
V
Q
--
T
V
V
Y
E
S
--
N
F
-----
G
D
G
M
FGK
V
F
S
P
I
L
L
K
H
H
N
-
C
A
M
E
E
I
R
A
R
G
MKE
M
R
-
I
C
D
T
L
E
P
V
M
Q
T
H
R
LVIRDEV
17
Fugue
58.12
18%
-11
- C2 -
4J1Q
1
A:
[20-445]
-----H
M
E
R
L
M
L
E
P
V
W
E
K
Q
N
E
E
L
S
Y
T
E
H
I
I
V
L
F
E
T
E
R
S
V
T
D
S
I
A
S
H
M
K
D
A
R
V
I
T
L
N
E
A
V
G
H
I
A
E
R
Y
Q
---
C
--
Y
M
Q
N
I
F
E
L
L
Q
S
---
K
V
R
K
-
L
S
A
G
R
I
I
I
Q
A
I
V
P
L
E
K
E
K
Q
L
F
A
-----
G
V
S
G
L
F
K
T
A
E
I
E
F
S
K
L
T
A
Q
V
I
-----
E
I
E
K
P
E
EMID
L
H
L
K
L
K
D
D
------
S
R
R
P
F
D
--
K
----
Q
I
R
Y
--------
E
A
G
Y
R
F
V
K
G
W
R
E
--
M
V
D
T
L
--
H
M
P
---
W
R
D
E
G
V
Y
L
I
T
-----------------------
G
G
A
G
S
L
G
L
L
F
A
K
E
I
A
N
R
T
G
R
S
T
I
V
L
T
----
G
R
S
V
L
S
E
D
K
E
N
E
L
E
A
L
R
S
I
G
--
A
E
V
V
Y
----------------------
R
E
A
D
V
S
D
---
Q
H
A
V
R
H
L
L
E
E
I
K
E
R
Y
------
G
T
L
N
G
I
I
H
G
A
---
G
S
S
K
D
R
--
F
I
I
H
K
T
N
E
E
F
Q
E
V
L
Q
P
K
V
S
G
-
L
L
H
V
D
E
C
S
K
D
F
-----
P
--
L
------
D
F
--------
F
I
F
F
--
S
S
V
S
G
C
L
--------------
G
N
A
G
Q
A
D
Y
-----------
A
A
A
N
S
F
M
D
---
A
F
A
E
Y
R
R
S
L
A
A
----------------------------------------
S
K
K
R
F
G
S
T
I
S
F
N
-----
W
P
L
W
E
E
G
G
M
Q
V
---
G
A
E
D
E
K
R
M
L
K
T
T
GM
V
P
M
P
T
D
--
S
G
-----
L
K
A
F
----
Y
Q
G
I
V
S
D
K
P
Q
V
F
V
M
E
G
Q
L
Q
K
----
M
K
-
Q
K
L
L
----------------
20
Fugue
56.40
14%
-11
- C3 -
3CUZ
4
MASY_ECOLI
A:
[4-532]
ATTTD
E
L
A
F
T
R
P
Y
G
E
Q
E
K
Q
I
L
T
A
E
A
V
E
F
L
T
E
L
V
T
H
F
T
P
Q
R
N
K
L
L
A
A
R
I
Q
Q
Q
Q
D
I
D
N
G
T
L
-
P
D
F
I
S
E
T
---
A
--
S
I
R
D
A
D
W
K
I
R
G
---
I
P
A
D
-
L
E
D
R
R
V
E
I
T
G
P
V
E
R
K
M
V
I
N
A
L
N
A----
N
V
K
V
F
M
A
D
F
E
D
S
-
L
A
P
D
W
N
K
V
-----
I
D
G
Q
I
N
----
L
R
D
A
V
N
G
T
I
S
Y
T
N
E
A
G
K
I
Y
Q
--
L
K
P
N
P
A
V
L
I
C
R
V
R
G
LHL
P
E
K
H
V
T
W
R
G
E
A
I
P
G
S
L
F
D
F
A
L
Y
F
F
---
H
N
Y
Q
A
L
L
A
K
G
S
GP
Y
F
Y
L
P
K
--
T
Q
S
W
Q
E
A
A
W
W
S
E
V
F
S
Y
A
E
D
R
F
N
L
P
R
-
G
T
I
K
A
T
L
L
I
E
T
L
P
A
V
F
Q
M
D
E
I
L
H
A
L
R
D
H
I
V
G
L
N
C
G
R
W
D
Y
I
F
S
Y
I
K
T
L
K
N
Y
P
--
D
-
R
---
V
L
P
D
R
Q
A
V
T
M
D
K
P
F
L
N
A
Y
S
R
L
L
I
K
T
C
H
K
R
----------------
G
A
F
A
M
G
G
M
A
A
F
--
I
P
S
K
D
E
E
H
N
N
Q
V
L
N
K
V
K
A
D
K
-
S
L
E
A
N
N
G
H
D
G
T
W
I
AHP
G
--
L
A
D
T
A
M
A
V
F
--------
N
D
I
L
--
G
S
R
K
N
Q
L
-------
E
V
M
R
E
Q
D
A
P
I
T
A
D
Q
L
L
A
P
C
D
G
E
RT
E
E
G
M
R
A
N
I
R
V
---
A
V
Q
Y
I
E
A
W
I
S
G
----
N
G
C
V
P
I
---------------
Y
---
G
---
L
M
E
D
A
--
A
T
A
E
I
S
R
T
S
I
W
Q
-----
W
I
H
H
Q
K
T
L
S
N
G
KPV
T
K
A
L
F
R
Q
M
L
G
E
E
--
M
K
V
I
A
S
--
E
L
-----
G
E
E
R
----
F
S
Q
G
R
F
D
D
A
A
-
R
L
M
E
Q
I
T
T
S
----
D
E
-
L
I
D
F
L
T
L
P
G
Y
R
L
LA------
15
Fugue
55.32
17%
-28
- C2 -
4XR7
-
PAN3_YEAST
B:
[1-456]
-----------
M
H
S
L
L
Q
Y
R
S
A
D
-----------
Q
L
F
I
P
N
N
------------------------
I
R
E
---
D
--
L
T
K
K
N
L
S
I
L
Q
V
---
F
P
S
S
-
G
K
V
I
P
S
I
V
Q
D
Y
F
N
L
V
P
L
N
F
N
N
K
-----
T
T
L
F
K
V
F
S
N
Y
D
G
-
K
A
Y
V
L
K
R
L
PNIDK
S
M
N
P
N
K
----
I
S
K
I
Y
Q
I
W
------
S
K
I
N
C
T
--
N
L
I
K
F
R
D
I
F
--------
Q
T
T
--
K
F
G
-
D
L
S
I
C
L
V
F
D
Y
--
Y
P
N
---
S
L
S
L
Y
D
Y
H
F
V
N
-----
F
P
K
FP
I
T
N
N
Y
L
W
I
Y
L
V
Q
L
T
N
V
I
N
S
I
H
S
-
Q
N
L
S
I
G
N
T
L
N
----------
W
R
K
V
L
I
T
G
D
P
G
R
I
K
L
S
H
C
N
F
M
D
L
L
F
N
D
D
T
D
T
V
V
S
--
S
T
I
---
E
G
Q
Q
Q
L
D
Y
K
Y
L
G
E
L
L
F
N
L
S
I
N
I
E
N
S
N
N
N
T
A
P
K
E
Y
----------
R
L
E
E
I
T
P
Q
S
I
D
D
--
M
R
Q
I
D
D
--
K
F
K
D
V
L
K
Y
L
I
S
D
-
N
G
D
S
K
K
S
I
H
D
L
T
----
S
--
H
F
Y
D
-------------
K
M
F
M
--
V
L
E
S
S
Q
T
-------
Y
T
E
Y
M
E
S
V
L
S
R
E
L
E
------------
N
G
R
L
F
R
L
V
---
N
K
L
N
C
I
F
G
R
I
E
----
S
R
I
D
I
N
---------------
W
---
S
---
E
S
G
T
K
--
F
P
I
I
L
F
Y
D
Y
V
F
H
-----
Q
V
D
S
N
---
G
K
P
---
I
M
D
L
T
H
V
L
R
C
L
N
--
K
L
D
A
G
I
--
Q
----------------
E
K
L
M
L
V
T
P
-
D
E
L
N
C
I
I
I
S
----
Y
K
E
L
K
D
L
I
E
S
T
F
R
S
I
T
Q
H-----
22
Fugue
50.47
16%
-12
* C3 *
4I9F
2
?
A:
[10-352]
----------------------
K
S
I
A
Q
E
H
D
C
L
L
I
D
L
D
G
T
V
F
C
G
R
Q
P
T
G
G
A
V
Q
S
L
S
Q
-
V
R
S
R
K
L
F
V
T
N
---
N
--
A
S
R
S
A
D
E
V
A
A
H
---
L
C
E
L
G
F
T
A
T
G
E
D
V
V
T
--------
S
A
Q
S
-----
A
A
H
L
L
A
G
Q
L
A
P
G
-
A
----
R
V
L
-----
I
V
G
T
E
A
----
L
A
N
E
V
A
A
V
------
G
L
R
P
V
R
--
R
--------------------------------------------------------------------------
F
E
D
R
P
D
A
V
V
Q
G
L
S
M
T
T
G
---------------------------------------------------------------
W
S
D
L
A
E
A
A
L
A
I
R
A
G
A
L
W
V
A
A
N
V
D
P
T
L
P
T
----
E
R
G
L
L
P
G
N
G
S
M
V
A
A
L
R
T
A
T
G
M
D
P
R
V
A
G
K
------
P
A
P
A
L
M
T
-
E
A
V
A
R
G
D
F
R
A
A
L
----
V
--
V
G
D
R
L
D
T
D
I
--------
E
G
A
N
A
A
G
L
P
S
L
M
V
-------
L
T
G
V
N
S
A
W
D
A
V
Y
A
E
P
-----------
V
R
R
P
T
Y
I
G
---
H
D
------------------
L
---------------
R
---
S
---
L
H
Q
D
S
--
K
L
L
A
V
A
P
Q
P
G
W
Q
-----
I
D
V
G
G
G
A
V
T
V
C
---
A
N
G
I
D
D
G
L
S
I
V
R
--
A
V
A
S
A
V
--
W
E
-----
A
R
A
A
----
D
L
H
Q
R
P
L
R
I
E
-
A
G
D
E
R
A
R
A
A
----
L
Q
-
R
W
S
L
M
R
S
D
------------
5
HHSearch
47.66
11%
-59
- C2 -
3J2M
-
TSP_BPT4
U:
[439-645]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
F
N
I
S
S
T
Y
A
A
I
D
G
N
Y
K
Y
Q
Y
D
K
Y
N
--------------------------
D
V
N
R
W
V
P
L
A
A
D
I
A
G
L
C
A
R
T
D
N
V
-----------
R
G
-
Q
I
L
N
V
---------------
I
--
K
L
A
I
E
--
Q
-
A
Q
R
D
R
L
Y
Q
E
A
I
N
----
P
--
V
T
G
T
G
G
D
-
G
--------
Y
V
L
Y
--
G
D
K
T
A
T
S
V------
P
S
P
---------------------------
N
V
R
R
---
L
F
N
M
L
K
T
N
I
G
R
----
S
S
K
Y
R
L
---------------
F
ELN
N
---
A
F
T
R
S
--
S
F
R
T
E
T
A
Q
Y
L
Q
G
-----
N
K
A
L
G
---------
G
I
Y
------
E
Y
R
--
V
V
C
D
T
T
NN
T
P
SVI--
D
R
N
E
----
F
V
A
T
F
Y
I
Q
P
A
-
R
S
I
N
Y
I
T
L
N
----
F
V
-
A
T
A
-----------------
11
HHSearch
42.97
15%
14
- C2 -
2QUP
1
?
A:
[64-123]
-----------------------------------------
E
E
L
R
K
Y
K
E
L
V
K
E
F
V
G
D
A
V
E
L
G
L
R
L
E
E
RNR
R
--
G
R
T
K
I
Y
K
I
V
K
E
---
V
D
R
K
-
L
L
D
L
T
D
A
V
L
A
K
E
K
K
G
L
D
I
L
N
M
V
-----
G
E
I
K
G
L
L
I
N
I
Y
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
41.72
25%
139
* C2 *
3HE5
-
?
A:
[0-46]
--------------------------------------
S
N
L
V
A
Q
L
E
N
E
V
A
S
L
E
N
E
N
E
T
L
K
K
K
N
L
H
K
K
---
D
--
L
I
A
Y
L
E
K
E
I
A
N
---
L
R
K
K
-
I
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
40.31
9%
-15
- C2 -
2P61
-
?
A:
[72-130]
-----------------------------------------
S
N
L
K
R
Y
K
N
A
I
K
E
F
L
K
L
I
E
K
K
I
Y
K
L
------N
S
G
R
A
R
L
H
L
V
V
E
E
---
V
N
E
K
-
L
M
D
L
T
E
K
I
M
K
N
E
W
Q
T
I
N
L
A
A
R
I
-----
E
E
I
N
G
L
I
L
N
L
Y
R
-
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
38.67
12%
-34
- C2 -
3J9Q
-
?
A:
[195-378]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
N
A
P
A
S
A
Y
A
A
G
L
F
A
W
T
D
A
E
Y
G
F
W
S
S
P
S
N
K
E
I
K
G
-
V
T
G
T
S
---------------
R
P
V
E
F
L
D
G
D
E
T
C
R
A
N
L
L
N
N
A
N
I
A
----
T
--
I
I
R
--
D
-
D
G
--------
Y
R
L
W
--
G
N
R
T
L
S
S
-------
D
S
K
W
--------------------------
A
F
-
V
---
T
R
V
R
T
M
D
L
V
M
D
A
I
L
A
G
H
K
W
A
V
---------------
D
---
R
GIT
K
T
Y
V
K
--
D
V
T
E
G
L
R
A
F
M
R
D
-----
L
K
N
Q
G
A
---------
V
------
I
N
F
E
--
V
Y
A
D
P
D
--
L
N
S
A
S
Q
L
A
Q
G
K
----
V
Y
W
N
I
R
F
T
D
V
-
P
P
A
E
N
P
N
F
R
----
V
E
-
V
T
D
Q
W
L
T
E
V
L
D
---------
2
PsiBlast_PDB
35.45
30%
-27
- C2 -
4W8L
-
XYNC_PAEBA
A:
[177-256]
------------------------------------------
A
R
E
A
D
P
D
A
V
L
V
I
N
D
Y
G
I
E
G
S
V
S
K
M
N
---
D
--
M
V
K
L
V
E
K
L
L
A
K
GTP
I
D
A
--
I
G
F
Q
M
H
V
S
M
Y
G
P
D
I
K
Q
I
R
E
A
F
N
R
A
A
A
L
G
V
H
I
Q
V
--
T
E
L
D
-
M
S
I
Y
S
G
N
S
-----
E
Q
E
K
P
V
----
T
D
E
M
M
L
E
Q
------
A
Y
R
Y
R
A
--
L
F
D
L
F
K
E
F
D
--------
D
R
G
V
M
D
S
V
T
L
W
G
L
A
D
D
G
T
W
--
L
D
D
---
F
P
V
K
G
R
K
D
A
P
L
-----
L
F
D
--
R
K
L
K
A
K
P
A
Y
W
A
L
V
D
P
S
T
L
P
V
Y
R
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
34.39
9%
10
- C2 -
3LML
-
?
A:
[300-454]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
P
R
L
A
N
-
D
E
A
E
E
A
L
Q
N
G
E
F
----
V
--
L
T
F
D
A
R
D
K
A
--------
V
Y
V
E
--
Q
D
L
N
S
L
T
-------
T
F
--
S
K
E
K
S
S
------------------
K
F
R
K
-
N
---
K
I
S
R
I
L
D
G
I
N
N
----
D
T
R
R
N
I
L
D
A
I
K
E
R
K
D
A
NTDIP
A
---
D
---
E
N
G
V
Q
--
F
I
L
S
M
Q
T
A
Y
L
N
E
-----
L
Q
D
S
G
A
---------
I
T
N
F
D
S
T
--
A
D
--
I
T
V
S
L
N
--
N
------
N
V
D
G
----
F
I
V
N
Q
S
I
E
P
V
-
D
S
G
E
K
F
Y
F
T
----
T
E
-
V
K
L
E
H
---------------
12
HHSearch
26.96
26%
175
- C2 -
3CIT
1
?
A:
[107-144]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
E
G
S
F
G
T
L
V
L
A
N
--
S
V
A
I
S
A
P
D
G
E
D
I
E
S
L
Q
L
-----
L
A
T
--
L
L
A
A
H
L
E
N
N
R
L
L
E
A
L
V
A
R
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
0.69
57%
2227
- C1 -
3OX7
-
?
P:
[8-14]
--------------------------------------------------------------------------------------------------------------
C
S
W
R
-----
G
L
E
N
H
A
M
C
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------