@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0121: (2015-12-22 )
MVGFEARTQQGAALRPTSHFVYESIYTAILEKRLAPAAKLSKETLGQIFRVSNGTIQRALTRLAEDGAVVMPPKEVASVARPDERQARQVLDARLLVESEVVRQLPAGLDPAALAELRALVDEEQACLAARDSAGLIRLAGRFHLRLAELTENPLLQGFVRGLVARASLDIALNKGAVYTAEACAAQRALLDALEDGDSAAAAALMDAYLRGLFARMRFLPPPTTDLREAFGMKAPSGEKRRRA
Atome Classification :
(20 SA)
.........10........20........30........40.-..-......50........60........70.----.-------------------......80..---------------.-------------------.....90......-------..100...-....-110.......120.......130------....-----...140.......150.......160..--------..-....170..-.-----..-..-.180.......190.......200.......210.......220.......230.......240..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MVGFEARTQQGAALRP
T
S
H
F
V
Y
E
S
I
Y
T
A
I
L
E
K
RLA
P
A
A
K
L
-
S
-
K
E
-
T
L
G
Q
I
F
RVSN
G
T
I
Q
R
A
L
T
R
LAED
G
A
V
VM
P
----
P
-------------------
K
E
V
A
S
VARP
D
---------------
E
-------------------
R
Q
A
R
Q
V
L
D
A
R
L
L
V
-------
E
S
E
V
V
R
QL-PAGL-
D
P
A
A
L
A
E
L
R
A
L
V
D
E
E
Q
A
C
L
AARD------SA
G
L
-----
I
R
L
A
G
R
F
H
L
R
L
A
E
LTE
N
P
L
L
Q
G
F
V
-
R
G
L
--------
V
A
-RA
S
L
D
I
-
A
L-N-----KG-
A
V
-
Y
T
A
E
A
C
A
A
Q
R
A
L
L
D
A
LEDG
D
S
A
A
A
A
A
L
M
D
A
Y
L
R
G
L
F
A
R
M
RFLPPP
T
T
D
L
R
E
A
FGMKAPSGEKRRRA
23
HHSearch
89.93
19%
-110
- C3 -
3SXY
-
?
A:
[10-210]
-----------------
R
T
K
V
Y
N
L
L
K
E
M
I
L
N
H
E
L
K
L
G
E
K
L
-
N
-
V
R
-
E
L
S
E
K
L
G
I
S
F
T
P
V
R
D
A
L
L
Q
L
A
T
E
G
L
V
K
V
V
----
P
-------------------
R
V
G
F
F
V
T
D
V
D
---------------
E
-------------------
K
F
I
R
E
T
I
E
T
R
I
M
M
-------
E
V
F
C
L
E
N
Y
-
F
D
K
I
A
G
S
E
E
L
L
E
I
K
G
E
I
D
D
V
E
K
S
---
A
K
------
R
E
I
F
-----
D
D
S
D
E
R
L
H
K
L
F
I
R
A
S
G
N
E
L
I
I
S
L
Y
-
E
K
I
--------
W
D
-
R
I
D
L
V
R
-
H
L
-
N
---------
E
-
R
Y
V
V
S
N
R
E
H
K
E
L
I
E
R
I
I
S
G
D
K
E
G
A
I
E
K
L
K
E
H
L
K
N
V
E
A
E
T
I
K
N
L
Y
T
---------------------
21
HHSearch
89.59
21%
-98
- C3 -
2HS5
1
?
A:
[27-233]
--------------
T
S
R
T
T
R
V
A
G
I
L
R
D
A
I
I
D
G
T
F
R
P
G
A
R
L
-
S
-
E
P
-
D
I
C
A
A
L
D
V
S
R
N
T
V
R
E
A
F
Q
I
L
I
E
D
R
L
V
A
H
E
----
L
-------------------
N
R
G
V
F
V
R
V
P
T
---------------
A
-------------------
E
D
I
T
E
L
Y
I
C
R
R
V
V
-------
E
C
A
G
V
N
G
F
---
D
P
-
A
T
G
D
L
S
R
V
A
E
A
L
D
L
A
D
E
R
Y
A
V
E
D
------
W
T
G
V
-----
G
T
A
D
I
H
F
H
S
A
L
A
S
L
N
N
S
N
R
I
D
E
L
M
-
R
S
V
--------
W
N
-
E
A
R
L
V
F
-
H
V
-
M
-----
D
D
A
H
R
-
F
H
G
P
Y
L
T
R
N
H
E
I
Y
D
A
L
A
A
G
N
T
E
A
A
G
Q
L
L
K
T
Y
L
E
D
A
E
A
Q
I
L
G
A
Y
R
----------------------
43
Fugue
89.20
21%
-94
- C3 -
2HS5
1
?
A:
[27-233]
--------------
T
S
R
T
T
R
V
A
G
I
L
R
D
A
I
I
D
G
T
F
R
P
G
A
R
L
-
S
-
E
P
-
D
I
C
A
A
L
D
V
S
R
N
T
V
R
E
A
F
Q
I
L
I
E
D
R
L
V
A
H
E
----
L
-------------------
N
R
G
V
F
V
R
V
P
T
---------------
A
-------------------
E
D
I
T
E
L
Y
I
C
R
R
V
V
-------
E
C
A
G
V
N
---
G
F
D
P
-
A
T
G
D
L
S
R
V
A
E
A
L
D
L
A
D
E
R
Y
A
V
E
D
------
W
T
G
V
-----
G
T
A
D
I
H
F
H
S
A
L
A
S
L
N
N
S
N
R
I
D
E
-
L
M
R
S
V
--------
W
N
-
E
A
R
L
V
F
-
H
V
M
D
-----
D
A
-
H
R
-
F
H
G
P
Y
L
T
R
N
H
E
I
Y
D
A
L
A
A
G
N
T
E
A
A
G
Q
L
L
K
T
Y
L
E
D
A
E
A
Q
I
L
G
A
Y
R
----------------------
1
PsiBlast_PDB
87.85
26%
-88
- C3 -
2HS5
1
?
A:
[40-221]
---------------------------
A
I
I
D
G
T
F
R
P
G
A
R
L
-
S
-
E
P
-
D
I
C
A
A
L
D
V
S
R
N
T
V
R
E
A
F
Q
I
L
I
E
D
R
L
V
A
H
E
----
L
-------------------
N
R
G
V
F
V
R
V
P
T
---------------
A
-------------------
E
D
I
T
E
L
Y
I
C
R
R
V
V
-------
E
C
A
G
V
N
G
F
D
P
A
T
G
-
D
L
S
R
V
A
E
A
L
D
L
A
D
E
R
---
Y
A
V
E
D
------
W
T
G
V
-----
G
T
A
D
I
H
F
H
S
A
L
A
S
L
N
N
S
N
R
I
D
E
L
M
-
R
S
V
--------
W
N
-
E
A
R
L
V
F
-
H
V
-
M
-----
D
D
-
A
H
R
F
H
G
P
Y
L
T
R
N
H
E
I
Y
D
A
L
A
A
G
N
T
E
A
A
G
Q
L
L
K
T
Y
L
E
D
A
E
A
Q
I
L
G
A
Y
R
----------------------
24
HHSearch
83.42
20%
-100
- C3 -
3C7J
1
?
A:
[20-230]
---------
E
Q
P
P
A
H
L
A
R
T
V
I
E
E
K
L
R
N
A
I
I
D
G
S
L
P
S
G
T
A
L
-
R
-
Q
Q
-
E
L
A
T
L
F
G
V
S
R
M
P
V
R
E
A
L
R
Q
L
E
A
Q
S
L
L
R
V
E
----
T
-------------------
H
K
G
A
V
V
A
P
L
I
---------------
T
-------------------
E
D
A
V
D
A
Y
A
L
R
I
L
L
-------
E
S
E
A
L
R
L
S
-
I
P
L
L
-
D
A
D
D
L
A
A
A
A
S
Y
I
E
Q
L
E
V
---
E
T
D
------
F
G
Q
I
-----
G
R
L
N
R
M
F
H
L
S
L
Y
A
K
T
H
N
K
R
L
M
R
L
V
-
E
E
G
--------
L
N
-
E
E
E
R
F
L
-
R
F
N
L
-----
S
S
-
M
G
-
L
G
K
L
S
Q
D
D
H
W
Q
L
L
R
L
A
E
Q
K
A
V
E
P
C
V
E
A
L
Q
Y
H
L
N
R
G
V
Q
A
V
T
Q
Y
L
Q
S
Q
K
A
G
N
V
---------------
22
HHSearch
81.28
20%
-93
- C3 -
3IHU
1
?
A:
[16-220]
---------------
S
A
S
D
T
V
F
F
G
I
M
S
G
L
E
L
G
T
F
V
P
G
Q
R
L
-
V
-
E
T
-
D
L
V
A
H
F
G
V
G
R
N
S
V
R
E
A
L
Q
R
L
A
A
E
G
I
V
D
L
Q
----
R
-------------------
H
R
G
A
V
I
R
R
L
S
---------------
L
-------------------
Q
E
T
L
D
V
L
D
V
A
E
R
M
-------
T
G
L
L
A
R
A
A
-
T
R
G
S
G
N
Q
P
Q
V
Q
A
L
R
A
S
V
Q
A
L
V
A
A
E
K
A
Q
D
------
G
E
T
F
-----
S
N
A
R
R
H
F
Y
R
T
L
L
E
M
G
D
N
R
E
L
R
R
L
F
-
P
T
I
--------
H
M
-
P
I
V
H
A
Q
-
H
R
-
L
--------
A
S
-
L
R
Q
M
R
L
D
D
Y
R
R
I
A
T
A
V
L
A
G
E
P
D
A
A
E
A
A
G
A
A
H
V
K
N
V
R
G
A
I
L
D
R
Q
-----------------------
26
HHSearch
79.59
19%
-96
- C3 -
2DI3
1
?
A:
[2-231]
-------------
S
V
K
A
H
E
S
V
M
D
W
V
T
E
E
L
R
S
G
R
L
K
I
G
D
H
L
-
P
S
E
R
-
A
L
S
E
T
L
G
V
S
R
S
S
L
R
E
A
L
R
V
L
E
A
L
G
T
I
S
T
A
TGSG
P
-------------------
R
S
G
T
I
I
T
A
A
P
GQ
A
L
S
L
S
V
T
L
Q
L
V
T
N
Q
-------------------
V
G
H
H
D
I
Y
E
T
R
Q
L
L
-------
E
G
W
A
A
L
H
S
-
S
A
E
R
-
G
--
D
W
D
V
A
E
A
L
L
E
K
M
D
D
P
--
S
L
P
------
L
E
D
F
-----
L
R
F
D
A
E
F
H
V
V
I
S
K
G
A
E
N
P
L
I
S
T
L
M
-
E
A
L
--------
R
L
-
S
V
A
D
H
T
V
A
R
-
A
R
AL--
P
D
W
R
A
-
T
S
A
R
L
Q
K
E
H
R
A
I
L
A
A
L
R
A
G
E
S
T
V
A
A
T
L
I
K
E
H
I
E
G
Y
Y
E
E
T
A
A
A
E
A
L
---------------------
25
HHSearch
75.85
16%
-100
* C3 *
1HW1
4
FADR_ECOLI
A:
[5-230]
-------------
A
Q
S
P
A
G
F
A
E
E
Y
I
I
E
S
I
W
N
N
R
F
P
P
G
T
I
L
-
P
A
E
R
-
E
L
S
E
L
I
G
V
T
R
T
T
L
R
E
V
L
Q
R
L
A
R
D
G
W
L
T
I
Q
----
H
-------------------
G
K
P
T
K
V
N
N
F
W
---------------
E
TSGLNI
L
E
T
L
A
R
L
D
HES
V
P
Q
L
I
D
N
L
L
S
V
R
T
N
I
-------
S
T
I
F
I
R
T
A
-
F
R
Q
H
-
P
D
K
A
Q
E
V
L
A
T
A
----
N
E
V
--
A
D
H
------
A
D
A
F
-----
A
E
L
D
Y
N
I
F
R
G
L
A
F
A
S
G
N
P
I
Y
G
L
I
L
-
N
G
M
--------
K
G
-
L
Y
T
R
I
G
-
R
H
Y
F
-----
A
N
-
P
E
-
A
R
S
L
A
L
G
F
Y
H
K
L
S
A
L
C
S
E
G
A
H
D
Q
V
Y
E
T
V
R
R
Y
G
H
E
S
G
E
I
W
H
R
M
Q
K
N
L
--------------------
46
Fugue
72.97
18%
-84
- C3 -
2DI3
1
?
A:
[2-232]
-------------
S
V
K
A
H
E
S
V
M
D
W
V
T
E
E
L
R
S
G
R
L
K
I
G
D
H
L
P
S
-
E
R
-
A
L
S
E
T
L
G
V
S
R
S
S
L
R
E
A
L
R
V
L
E
A
L
G
T
I
S
T
A
----
T
GSGPRS
G
T
I
I
TAAPGQ
A
L
S
L
S
V
T
L
Q
L
V
T
N
---------------
Q
-------------------
V
G
H
H
D
I
Y
E
T
R
Q
L
L
-------
E
G
W
A
A
L
H
S
-
S
A
E
R
-
G
D
W
D
V
A
E
A
L
L
E
K
M
D
D
P
S
----
L
P
------
L
E
D
F
-----
L
R
F
D
A
E
F
H
V
V
I
S
K
G
A
E
N
P
L
I
S
T
L
M
-
E
A
L
--------
R
L
-
S
V
A
D
H
T
-
V
A
-
R
A
R
ALP
D
W
-
R
A
-
T
S
A
R
L
Q
K
E
H
R
A
I
L
A
A
L
R
A
G
E
S
T
V
A
A
T
L
I
K
E
H
I
E
G
Y
Y
E
E
T
A
A
A
E
A
L
---------------------
45
Fugue
70.96
14%
-92
- C3 -
1E2X
2
FADR_ECOLI
A:
[10-231]
--------------
Q
S
P
A
G
F
A
E
E
Y
I
I
E
S
I
W
N
N
R
F
P
P
G
T
I
L
P
A
-
E
R
-
E
L
S
E
L
I
G
V
T
R
T
T
L
R
E
V
L
Q
R
L
A
R
D
G
W
L
T
I
Q
----
H
-------------------
G
K
P
T
K
V
N
N
F
W
---------------
E
-------------------
T
S
G
L
N
I
L
E
T
L
A
R
L
D
HES
V
P
Q
L
I
D
N
L
L
S
V
-
R
T
N
I
-
S
T
I
F
I
R
T
A
F
R
Q
H
P
D
K
A
Q
E
V
L
A
T
A
NEVADH
A
D
A
F
-----
A
E
L
D
Y
N
I
F
R
G
L
A
F
A
S
G
N
P
I
Y
G
L
I
L
-
N
G
M
--------
K
G
L
Y
T
R
I
G
R
-
H
Y
-
F
-----
A
N
-
P
E
-
A
R
S
L
A
L
G
F
Y
H
K
L
S
A
L
C
S
E
G
A
H
D
Q
V
Y
E
T
V
R
R
Y
G
H
E
S
G
E
I
W
H
R
M
Q
-----------------------
14
PsiBlast_PDB
55.58
27%
-125
- C3 -
1E2X
1
FADR_ECOLI
A:
[15-101]
-------------------
F
A
E
E
Y
I
I
E
S
I
W
N
N
R
F
P
P
G
T
I
L
-
P
-
A
E
R
E
L
S
E
L
I
G
V
T
R
T
T
L
R
E
V
L
Q
R
L
A
R
D
G
W
L
T
I
Q
----
H
-------------------
G
K
P
T
K
V
N
N
F
W
---------------
E
-------------------
T
S
G
L
N
I
L
E
T
L
A
R
L
-------
D
H
E
S
V
P
Q
L
-
I
D
N
L
-
L
S
V
R
T
N
I
S
T
I
F
I
R
T
A
F
R
Q
H
P
D
K
A
------
Q
E
V
L
-----
A
T
A
N
E
V
A
D
H
A
D
A
F
A
E
L
D
Y
N
I
F
R
G
L
-
A
F
A
--------
S
G
-
N
P
I
Y
G
L
-
I
L
-
N
-----
G
M
-
K
G
-
L
Y
T
R
I
G
R
H
Y
F
A
N
P
E
A
R
S
L
A
L
G
F
Y
H
K
L
S
A
L
C
S
E
G
A
H
D
Q
V
Y
E
T
V
R
R
Y
G
H
E
S
G
E
I
W
H
R
M
Q
---------
12
PsiBlast_PDB
53.63
27%
-123
- C3 -
1HW1
2
FADR_ECOLI
A:
[11-97]
-------------------
F
A
E
E
Y
I
I
E
S
I
W
N
N
R
F
P
P
G
T
I
L
-
P
-
A
E
R
E
L
S
E
L
I
G
V
T
R
T
T
L
R
E
V
L
Q
R
L
A
R
D
G
W
L
T
I
Q
----
H
-------------------
G
K
P
T
K
V
N
N
F
W
---------------
E
-------------------
T
S
G
L
N
I
L
E
T
L
A
R
L
-------
D
H
E
S
V
P
Q
L
-
I
D
N
L
-
L
S
V
R
T
N
I
S
T
I
F
I
R
T
A
F
R
Q
H
P
D
K
A
------
Q
E
V
L
-----
A
T
A
N
E
V
A
D
H
A
D
A
F
A
E
L
D
Y
N
I
F
R
G
L
-
A
F
A
--------
S
G
-
N
P
I
Y
G
L
-
I
L
-
N
-----
G
M
-
K
G
-
L
Y
T
R
I
G
R
H
Y
F
A
N
P
E
A
R
S
L
A
L
G
F
Y
H
K
L
S
A
L
C
S
E
G
A
H
D
Q
V
Y
E
T
V
R
R
Y
G
H
E
S
G
E
I
W
H
R
M
Q
K
N
L
------
29
HHSearch
53.21
28%
-141
- C3 -
3BWG
1
YYDK_BACSU
A:
[8-73]
------------------
Q
Q
I
A
T
E
I
E
T
Y
I
E
E
H
Q
L
Q
Q
G
D
K
L
-
P
V
L
E
-
T
L
M
A
Q
F
E
V
S
K
S
T
I
T
K
S
L
E
L
L
E
Q
K
G
A
I
F
Q
V
----
R
-------------------
G
S
G
I
F
V
R
K
H
K
---------------
R
-------------------
K
G
Y
I
S
L
L
S
N
Q
G
D
F
-------
N
V
T
S
K
V
I
E
-
L
D
V
R
-
K
P
T
P
E
A
A
E
N
L
N
I
G
M
D
E
D
I
Y
Y
V
K
R
------
V
R
Y
I
-----
N
G
Q
T
L
C
Y
E
E
S
Y
Y
T
K
S
I
V
T
Y
L
N
N
E
I
-
V
S
H
--------
S
I
-
F
H
Y
I
R
E
-
G
L
-
G
-----
L
K
-
I
G
-
F
S
D
L
F
L
H
V
G
Q
L
N
E
E
E
A
E
Y
L
G
L
E
A
G
L
P
K
L
Y
I
E
S
I
F
H
L
T
N
G
Q
P
F
D
Y
S
K
I
S
Y
N
Y
E
Q
S
Q
F
V
V
Q
A
N
S
----
13
PsiBlast_PDB
52.37
27%
-121
- C3 -
1HW2
3
FADR_ECOLI
A:
[11-97]
-------------------
F
A
E
E
Y
I
I
E
S
I
W
N
N
R
F
P
P
G
T
I
L
-
P
-
A
E
R
E
L
S
E
L
I
G
V
T
R
T
T
L
R
E
V
L
Q
R
L
A
R
D
G
W
L
T
I
Q
----
H
-------------------
G
K
P
T
K
V
N
N
F
W
---------------
E
-------------------
T
S
G
L
N
I
L
E
T
L
A
R
L
-------
D
H
E
S
V
P
Q
L
-
I
D
N
L
-
L
S
V
R
T
N
I
S
T
I
F
I
R
T
A
F
R
Q
H
P
D
K
A
------
Q
E
V
L
-----
A
T
A
N
E
V
A
D
H
A
D
A
F
A
E
L
D
Y
N
I
F
R
G
L
-
A
F
A
--------
S
G
-
N
P
I
Y
G
L
-
I
L
-
N
-----
G
M
-
K
G
-
L
Y
T
R
I
G
R
H
Y
F
A
N
P
E
A
R
S
L
A
L
G
F
Y
H
K
L
S
A
L
C
S
E
G
A
H
D
Q
V
Y
E
T
V
R
R
Y
G
H
E
S
G
E
I
W
H
R
M
Q
K
--------
15
PsiBlast_PDB
52.32
27%
-117
- C3 -
1H9G
-
FADR_ECOLI
A:
[15-101]
-------------------
F
A
E
E
Y
I
I
E
S
I
W
N
N
R
F
P
P
G
T
I
L
-
P
-
A
E
R
E
L
S
E
L
I
G
V
T
R
T
T
L
R
E
V
L
Q
R
L
A
R
D
G
W
L
T
I
Q
----
H
-------------------
G
K
P
T
K
V
N
N
F
W
---------------
E
-------------------
T
S
G
L
N
I
L
E
T
L
A
R
L
-------
D
H
E
S
V
P
Q
L
-
I
D
N
L
-
L
S
V
R
T
N
I
S
T
I
F
I
R
T
A
F
R
Q
H
P
D
K
A
------
Q
E
V
L
-----
A
T
A
N
E
V
A
D
H
A
D
A
F
A
E
L
D
Y
N
I
F
R
G
L
-
A
F
A
--------
S
G
-
N
P
I
Y
G
L
-
I
L
-
N
-----
G
M
-
K
G
-
L
Y
T
R
I
G
R
H
Y
F
A
N
P
E
A
R
S
L
A
L
G
F
Y
H
K
L
S
A
L
C
S
E
G
A
H
D
Q
V
Y
E
T
V
R
R
Y
G
H
E
S
G
E
I
W
H
R
M
Q
---------
2
PsiBlast_PDB
51.74
25%
-10
- C3 -
4P9F
-
?
A:
[23-155]
---------------------------------
L
K
P
G
A
R
L
-
I
-
T
K
-
N
L
A
E
Q
L
G
M
S
I
T
P
V
R
E
A
L
L
R
L
V
S
V
N
A
L
S
V
A
----
P
-------------------
A
Q
A
F
T
V
P
E
V
G
---------------
K
-------------------
R
Q
L
D
E
I
N
R
I
R
Y
E
L
-------
E
L
M
A
V
A
L
A
-
V
E
N
L
-
T
P
Q
D
L
A
E
L
Q
E
L
L
E
K
L
Q
Q
A
Q
E
K
G
D
------
M
E
Q
I
-----
I
N
V
N
R
L
F
R
L
A
I
Y
H
R
S
N
M
P
I
L
C
E
M
I
-
E
Q
L
--------
W
V
-
R
M
G
P
G
L
-
H
Y
-
L
-----
Y
E
-
A
I
-
N
P
A
E
L
R
E
H
I
E
N
Y
H
L
L
L
A
A
L
K
A
K
D
K
E
G
C
R
H
C
L
A
E
I
M
Q
Q
N
I
A
I
L
Y
Q
Q
Y
N
-------------------
3
PsiBlast_PDB
51.49
28%
-68
- C3 -
2DI3
1
?
A:
[101-223]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
R
Q
L
-
L
E
G
W
-
A
A
L
H
S
S
A
E
R
G
D
W
D
V
A
E
A
L
L
E
K
M
D
------
D
P
S
L
P
L
E
D
F
L
R
F
D
A
E
F
H
V
V
I
S
K
G
A
E
N
P
L
I
S
T
L
M
-
E
A
L
R
L
S
V
A
D
H
T
V
A
-
R
A
R
----
A
L
-
P
-----
D
W
-
R
A
-
T
S
A
R
L
Q
K
E
H
R
A
I
L
A
A
L
R
A
G
E
S
T
V
A
A
T
L
I
K
E
H
I
E
G
Y
Y
E
E
T
A
A
A
E
A
L
---------------------
16
PsiBlast_PDB
51.40
27%
-121
- C3 -
1H9T
3
FADR_ECOLI
A:
[15-101]
-------------------
F
A
E
E
Y
I
I
E
S
I
W
N
N
R
F
P
P
G
T
I
L
-
P
-
A
E
R
E
L
S
E
L
I
G
V
T
R
T
T
L
R
E
V
L
Q
R
L
A
R
D
G
W
L
T
I
Q
----
H
-------------------
G
K
P
T
K
V
N
N
F
W
---------------
E
-------------------
T
S
G
L
N
I
L
E
T
L
A
R
L
-------
D
H
E
S
V
P
Q
L
-
I
D
N
L
-
L
S
V
R
T
N
I
S
T
I
F
I
R
T
A
F
R
Q
H
P
D
K
A
------
Q
E
V
L
-----
A
T
A
N
E
V
A
D
H
A
D
A
F
A
E
L
D
Y
N
I
F
R
G
L
-
A
F
A
--------
S
G
-
N
P
I
Y
G
L
-
I
L
-
N
-----
G
M
-
K
G
-
L
Y
T
R
I
G
R
H
Y
F
A
N
P
E
A
R
S
L
A
L
G
F
Y
H
K
L
S
A
L
C
S
E
G
A
H
D
Q
V
Y
E
T
V
R
R
Y
G
H
E
S
G
E
I
W
H
R
M
Q
K
N
L
L
A
I
Q
G
R
28
HHSearch
49.67
25%
-138
- C3 -
3EDP
1
?
A:
[7-77]
-------------
K
K
P
L
F
E
V
I
A
S
K
I
K
D
S
I
N
R
D
E
Y
K
T
G
--
M
-
P
N
E
T
-
A
L
Q
E
I
Y
S
S
S
R
T
T
I
R
R
A
V
D
L
L
V
E
E
G
L
V
V
R
K
----
N
-------------------
G
V
G
L
Y
V
Q
P
K
L
---------------
T
-------------------
A
Q
N
I
L
E
M
T
G
V
M
K
N
-------
L
K
K
D
I
K
D
F
-
Y
I
R
K
-
A
G
K
F
Y
A
E
I
F
G
M
K
E
N
E
L
V
Y
S
I
K
F
V
------
Q
K
S
E
-----
H
G
A
T
L
D
R
L
I
L
P
L
G
L
Y
P
D
L
Q
A
K
D
F
Q
-
I
I
N
--------
I
I
-
E
L
V
N
S
G
-
K
Y
-
K
-----
L
F
-
E
L
-
E
Q
E
L
Q
L
I
L
A
G
N
E
Q
I
K
N
M
H
L
N
E
N
D
P
V
F
K
L
S
S
V
F
Y
A
E
N
D
M
P
I
A
I
Q
Y
H
Y
E
D
A
E
S
T
K
Y
V
V
D
F
N
-------
19
PsiBlast_PDB
48.93
25%
-120
- C3 -
4P9U
-
FADR_VIBCH
E:
[10-87]
-------------------
Y
I
I
E
S
I
W
N
G
----
R
F
P
P
G
S
I
L
-
P
-
A
E
R
E
L
S
E
L
I
G
V
T
R
T
T
L
R
E
V
L
Q
R
L
A
R
D
G
W
L
T
I
Q
----
H
-------------------
G
K
P
T
K
V
N
Q
F
M
---------------
E
-------------------
T
S
G
L
H
I
L
D
T
L
M
T
L
-------
D
A
E
N
A
T
S
I
-
V
E
D
L
-
L
A
A
R
T
N
I
S
P
I
F
M
R
Y
A
F
K
L
N
K
E
S
A
------
E
R
I
M
-----
I
N
V
I
E
S
C
E
A
L
V
N
A
P
S
W
D
A
F
I
A
A
S
P
-
Y
A
E
--------
K
I
-
Q
Q
H
V
K
E
-
D
S
-
E
-----
K
D
-
E
L
-
K
R
Q
E
I
L
I
A
K
T
F
N
F
Y
D
Y
M
L
F
Q
R
L
A
F
H
S
G
N
Q
I
Y
G
L
I
F
N
G
L
K
K
L
Y
D
R
V
G
S
Y
Y
F
S
N
P
Q
A
R
E
L
A
M
E
F
Y
R
Q
L