@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4192: (2016-02-24 )
MIRLEKVNKWYGAYHALADVDEQVGRGEVVVVCGPSGSGKSTLIRTLNRLEPIQGGRILIDGQDIHAPGLDLNRFRSHIGFVFQQFNLFPHLNVLDNCTLASLRLRGLKPAEARRQAMALLERVGLADKAAAFPARLSGGQQQRVAIARALAMEPPLMLFDEPTSALDPEMVGEVLLVMRDLARDGMTMVVVTHEMGFAHDVADRVLFMDAGRVLERASPDDFFNRPQHPRARKFLADIRTPFAQPL
Atome Classification :
(56 SA)
-.........10.-----.----......20.----.......30........40........50---.........60.-------------...-.-----------...70....----....80...--.....90........100----..-......110....-...---120-.......130-..--......140.......150.-......160.......170.......180-.-.-.-....190.......200.......210........220.......230.......240.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MI
R
L
E
K
V
N
K
W
Y
G
-----
A
----
Y
H
A
L
A
D
V
D
E
----QVGRG
E
V
V
V
V
CGPSGS
G
K
S
T
L
I
R
T
L
N
RL----EPIQG
G
R
I
L
I
DG-------------QDI-H-----------APGL
D
L
N
R
F
----
R
S
H
I
G
F
V
F
Q
--
Q
FNLFPHLNVLDNCT
L
A
-----
S
L
-RLRGLK
P
A
E
A
R
R
Q
-
A
M
A
---
L
L
E
-RVGLA
D
K
A-A-AF--
P
A
RLSGG
Q
Q
Q
R
V
A
I
A
R
A
LAM-EP
P
L
M
L
FDEPTSAL
D
P
E
M
V
G
E
V
L
L
V
M
R
D
L
-A-R-D-
G
M
T
M
V
V
V
T
HEMGF
A
H
D
V
A
D
R
V
L
F
MDA-
G
R
V
LERA
S
P
D
D
FFNRPQH
P
R
A
R
K
F
L
A
D
IRTPFAQPL
121
HHSearch
97.11
58%
-128
- C1 -
2OLJ
4
?
A:
[24-263]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-------
4
PsiBlast_PDB
95.98
58%
-127
- C1 -
2OLJ
4
?
A:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
6
PsiBlast_PDB
95.62
58%
-125
- C1 -
2OUK
1
?
A:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
27
PsiBlast_CBE
94.79
58%
-117
- C1 -
2OUK
2
?
D:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
25
PsiBlast_CBE
93.93
58%
-125
- C1 -
3C4J
4
?
B:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
8
PsiBlast_PDB
93.88
58%
-120
- C1 -
3C4J
3
?
A:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
32
PsiBlast_CBE
93.74
58%
-121
- C1 -
2OLK
2
?
B:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
21
PsiBlast_CBE
93.57
58%
-115
- C1 -
4U02
1
?
D:
[4-241]
-
I
I
R
I
R
N
L
H
K
W
F
G
-----
P
----
L
H
V
L
K
G
I
H
L
----
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
----
E
D
F
Q
E
G
E
V
V
V
D
G
-------------
L
S
V
-------------
K
D
D
R
A
L
R
E
I
----
R
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
-----
P
M
-
R
V
R
R
W
P
R
E
K
A
E
K
K
-
A
L
E
---
L
L
E
-
R
V
G
I
L
D
Q
A
-
R
-
K
Y
--
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
-
Q
-
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
-
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
--------
1
PsiBlast_PDB
93.45
58%
-121
- C1 -
4U00
3
?
A:
[4-241]
-
I
I
R
I
R
N
L
H
K
W
F
G
-----
P
----
L
H
V
L
K
G
I
H
L
----
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
----
E
D
F
Q
E
G
E
V
V
V
D
G
-------------
L
S
V
-------------
K
D
D
R
A
L
R
E
I
----
R
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
-----
P
M
-
R
V
R
R
W
P
R
E
K
A
E
K
K
-
A
L
E
---
L
L
E
-
R
V
G
I
L
D
Q
A
-
R
-
K
Y
--
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
-
Q
-
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
-
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
--------
2
PsiBlast_PDB
92.90
58%
-116
- C1 -
4U02
1
?
A:
[4-241]
-
I
I
R
I
R
N
L
H
K
W
F
G
-----
P
----
L
H
V
L
K
G
I
H
L
----
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
----
E
D
F
Q
E
G
E
V
V
V
D
G
-------------
L
S
V
-------------
K
D
D
R
A
L
R
E
I
----
R
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
-----
P
M
-
R
V
R
R
W
P
R
E
K
A
E
K
K
-
A
L
E
---
L
L
E
-
R
V
G
I
L
D
Q
A
-
R
-
K
Y
--
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
-
Q
-
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
-
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
--------
28
PsiBlast_CBE
92.89
58%
-120
- C1 -
2OUK
1
?
C:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
30
PsiBlast_CBE
92.82
58%
-123
- C1 -
2OLK
1
?
D:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
31
PsiBlast_CBE
92.66
58%
-121
- C1 -
2OLK
1
?
C:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
29
PsiBlast_CBE
92.16
58%
-117
- C1 -
2OUK
2
?
B:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
3
PsiBlast_PDB
91.67
58%
-117
- C1 -
3C41
3
?
J:
[3-241]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
23
PsiBlast_CBE
91.61
58%
-119
- C1 -
4U02
1
?
B:
[4-241]
-
I
I
R
I
R
N
L
H
K
W
F
G
-----
P
----
L
H
V
L
K
G
I
H
L
----
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
----
E
D
F
Q
E
G
E
V
V
V
D
G
-------------
L
S
V
-------------
K
D
D
R
A
L
R
E
I
----
R
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
-----
P
M
-
R
V
R
R
W
P
R
E
K
A
E
K
K
-
A
L
E
---
L
L
E
-
R
V
G
I
L
D
Q
A
-
R
-
K
Y
--
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
-
Q
-
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
-
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
--------
7
PsiBlast_PDB
91.59
58%
-118
- C1 -
2Q0H
4
?
A:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
5
PsiBlast_PDB
91.52
58%
-123
- C1 -
2OLK
1
?
A:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
22
PsiBlast_CBE
91.13
58%
-120
- C1 -
4U02
1
?
C:
[4-241]
-
I
I
R
I
R
N
L
H
K
W
F
G
-----
P
----
L
H
V
L
K
G
I
H
L
----
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
----
E
D
F
Q
E
G
E
V
V
V
D
G
-------------
L
S
V
-------------
K
D
D
R
A
L
R
E
I
----
R
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
-----
P
M
-
R
V
R
R
W
P
R
E
K
A
E
K
K
-
A
L
E
---
L
L
E
-
R
V
G
I
L
D
Q
A
-
R
-
K
Y
--
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
-
Q
-
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
-
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
--------
13
PsiBlast_PDB
91.02
53%
-123
- C1 -
4YMW
-
?
J:
[1-239]
-
M
I
F
V
N
D
V
Y
K
N
F
G
-----
S
----
L
E
V
L
K
G
V
T
L
----
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
-----------
N
G
K
V
N
I
N
K
V
----
R
Q
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
-----
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
-
A
V
D
---
L
L
A
-
K
V
G
L
L
D
K
K
-
D
-
Q
Y
--
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
--------
35
PsiBlast_CBE
90.38
53%
-125
- C1 -
4YMU
2
?
A:
[1-239]
-
M
I
F
V
N
D
V
Y
K
N
F
G
-----
S
----
L
E
V
L
K
G
V
T
L
----
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
-----------
N
G
K
V
N
I
N
K
V
----
R
Q
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
-----
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
-
A
V
D
---
L
L
A
-
K
V
G
L
L
D
K
K
-
D
-
Q
Y
--
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
--------
33
PsiBlast_CBE
90.37
58%
-120
- C1 -
2OLJ
3
?
B:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
24
PsiBlast_CBE
89.96
58%
-121
- C1 -
3C41
3
?
K:
[3-241]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
34
PsiBlast_CBE
89.93
53%
-122
- C1 -
4YMV
1
?
A:
[1-239]
-
M
I
F
V
N
D
V
Y
K
N
F
G
-----
S
----
L
E
V
L
K
G
V
T
L
----
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
-----------
N
G
K
V
N
I
N
K
V
----
R
Q
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
-----
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
-
A
V
D
---
L
L
A
-
K
V
G
L
L
D
K
K
-
D
-
Q
Y
--
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
--------
12
PsiBlast_PDB
89.76
53%
-124
- C1 -
4YMV
1
?
J:
[1-239]
-
M
I
F
V
N
D
V
Y
K
N
F
G
-----
S
----
L
E
V
L
K
G
V
T
L
----
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
-----------
N
G
K
V
N
I
N
K
V
----
R
Q
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
-----
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
-
A
V
D
---
L
L
A
-
K
V
G
L
L
D
K
K
-
D
-
Q
Y
--
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
--------
26
PsiBlast_CBE
89.30
58%
-123
- C1 -
2Q0H
4
?
B:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
----
L
E
V
L
K
G
I
N
V
----
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
----
E
D
F
D
E
G
E
I
I
I
D
G
-------------
I
N
L
-
K
-----------
A
K
D
T
N
L
N
K
V
----
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-----
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
-
A
M
E
---
L
L
D
-
K
V
G
L
K
D
K
A
-
H
-
A
Y
--
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
--------
11
PsiBlast_PDB
88.95
53%
-123
- C1 -
4YMU
2
?
J:
[1-239]
-
M
I
F
V
N
D
V
Y
K
N
F
G
-----
S
----
L
E
V
L
K
G
V
T
L
----
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
----
E
E
P
T
K
G
E
V
F
I
D
G
-------------
V
K
I
-
N
-----------
N
G
K
V
N
I
N
K
V
----
R
Q
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
-----
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
-
A
V
D
---
L
L
A
-
K
V
G
L
L
D
K
K
-
D
-
Q
Y
--
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
--------
14
PsiBlast_PDB
85.97
46%
-125
- C1 -
1B0U
4
HISP_SALTY
A:
[12-253]
-------
L
H
K
R
Y
G
-----
G
----
H
E
V
L
K
G
V
S
L
----
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
----
E
K
P
S
E
G
A
I
I
V
N
G
-------------
Q
N
I
-
N
L
V
R
D
KDGQLKV
A
D
K
N
Q
L
R
L
L
----
R
T
R
L
T
M
V
F
Q
--
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
-----
P
I
-
Q
V
L
G
L
S
K
H
D
A
R
E
R
-
A
L
K
---
Y
L
A
-
K
V
G
I
D
E
R
A
Q
G
-
K
Y
--
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
-
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
-
A
-
E
-
E
-
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
-
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
L
Q
Q
F
L
-----------
108
Fugue
78.10
45%
-126
- C1 -
1B0U
4
HISP_SALTY
A:
[5-261]
N
K
L
H
V
I
D
L
H
K
R
Y
G
-----
G
-------
H
E
V
L
K
-
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
EKPS----
E
G
A
I
I
V
N
G
QNI
N
L
V
R
D
KDGQL
K
V
A
-
D
-----------
K
N
Q
L
R
L
L
R
T
-----
R
-
L
T
M
V
F
Q
--
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
PIQVL------
G
L
S
K
H
D
A
R
E
R
-
A
L
K
---
Y
L
A
-
K
V
G
I
D
E
R
A
-
Q
-
G
-KY
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E-
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
-
A
-
E
-
E
-
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
-Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
-
Q
S
--
P
R
L
Q
Q
F
L
K
G
S
L
K
K
L
E
45
PsiBlast_CBE
69.46
40%
-124
- C1 -
3TIF
7
Y796_METJA
A:
[1-223]
-
M
V
K
L
K
N
V
T
K
T
Y
K
-----
M
GE
E
I
I
Y
A
L
K
N
V
N
L
----
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
----
D
K
P
T
E
G
E
V
Y
I
D
---------------
N
I
-
K
-----------
T
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
-----
L
I
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
---
C
L
K
-
M
A
E
L
E
E
R
F
-
A
-
N
H
K-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
-
E
-
D
-
G
K
T
V
V
V
V
T
H
D
I
N
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
-
G
E
V
---------------------------------
42
PsiBlast_CBE
69.43
40%
-128
- C1 -
1L2T
4
Y796_METJA
B:
[1-223]
-
M
I
K
L
K
N
V
T
K
T
Y
K
-----
M
GEEI
I
Y
A
L
K
N
V
N
L
----
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
----
D
K
P
T
E
G
E
V
Y
I
D
---------------
N
I
-
K
-----------
T
N
D
L
D
D
D
E
L
TKIR
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
-----
L
I
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
---
C
L
K
-
M
A
E
L
E
E
R
F
-
A
-
N
H
K-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
-
E
-
D
-
G
K
T
V
V
V
V
T
H
D
I
N
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
-
G
E
V
---------------------------------
92
PsiBlast_CBE
68.61
34%
-110
- C1 -
3FVQ
3
FBPC_NEIG1
B:
[5-241]
--
L
H
I
G
H
L
S
K
S
F
Q
-----
N
----
T
P
V
L
N
D
I
S
L
----
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
----
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
-
F
-----------
S
K
N
T
N
L
P
V
R
----
E
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
-----
L
G
-
N
G
K
G
-
R
T
A
Q
E
R
Q
R
-
I
E
A
---
M
L
E
-
L
T
G
I
S
E
L
A
-
G
-
R
Y
--
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
-
L
-
R
A
N
-
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
G
E
---------
19
PsiBlast_PDB
68.50
40%
-127
- C1 -
1L2T
4
Y796_METJA
A:
[1-223]
-
M
I
K
L
K
N
V
T
K
T
Y
K
-----
M
GE
E
I
I
Y
A
L
K
N
V
N
L
----
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
----
D
K
P
T
E
G
E
V
Y
I
D
---------------
N
I
-
K
-----------
T
N
D
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
-----
L
I
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
---
C
L
K
-
M
A
E
L
E
E
R
F
-
A
-
N
H
K-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
-
E
-
D
-
G
K
T
V
V
V
V
T
H
D
I
N
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
-
G
E
V
---------------------------------
78
PsiBlast_CBE
68.26
31%
-119
- C1 -
1VCI
1
?
A:
[13-250]
--
V
K
L
E
N
L
T
K
R
F
G
-----
N
----
F
T
A
V
N
K
L
N
L
----
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
----
E
E
P
T
E
G
R
I
Y
F
G
D
-------------
R
D
V
T
Y
-----------
L
P
P
K
D
R
N
---------
I
S
M
V
F
Q
--------
H
M
T
V
Y
E
N
I
A
F
------
P
L
---
K
K
F
P
K
D
E
I
D
K
R
-
V
R
W
---
A
A
E
-
L
L
Q
I
E
E
L
L
-
N
-
R
Y
--
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
-
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
-
Q
-
Q
-
K
L
K
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
-
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
P
N
S
V
F
V
A
T
F
I
G
----------
44
PsiBlast_CBE
67.80
40%
-128
- C1 -
3TIF
7
Y796_METJA
B:
[1-223]
-
M
V
K
L
K
N
V
T
K
T
Y
K
-----
M
GEEI
I
Y
A
L
K
N
V
N
L
----
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
----
D
K
P
T
E
G
E
V
Y
I
D
---------------
N
I
-
K
-----------
T
N
D
L
D
D
D
E
L
TKIR
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
-----
L
I
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
---
C
L
K
-
M
A
E
L
E
E
R
F
-
A
-
N
H
K-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
-
E
-
D
-
G
K
T
V
V
V
V
T
H
D
I
N
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
-
G
E
V
---------------------------------
80
PsiBlast_CBE
67.43
34%
-121
- C1 -
4MKI
4
ECFA2_CALS4
A:
[7-236]
--
I
K
V
E
N
V
S
F
I
Y
N
EGTPY
A
----
T
V
A
L
K
D
I
N
F
----
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
----
L
K
P
S
K
G
K
I
Y
I
N
G
-------------
I
D
I
-
T
-----------
D
K
K
V
S
L
K
D
I
----
R
K
Q
V
G
L
V
F
Q
YP
E
Y
Q
L
F
E
E
-
T
V
F
K
D
I
A
F
G
-----
P
S
-
N
L
-
G
L
S
E
E
E
V
K
E
R
-
V
Y
E
---
A
M
E
-
I
V
G
I
S
K
E
L
-
A
D
K
S
--
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
-
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
-
H
D
K
-
Y
-
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
-
G
K
I
E
L
I
G
T
P
R
E
V
F
-----------------------
79
PsiBlast_CBE
66.74
34%
-119
- C1 -
4MKI
4
ECFA2_CALS4
B:
[7-236]
--
I
K
V
E
N
V
S
F
I
Y
N
EGTPY
A
----
T
V
A
L
K
D
I
N
F
----
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
----
L
K
P
S
K
G
K
I
Y
I
N
G
-------------
I
D
I
-
T
-----------
D
K
K
V
S
L
K
D
I
----
R
K
Q
V
G
L
V
F
Q
YP
E
Y
Q
L
F
E
E
-
T
V
F
K
D
I
A
F
G
-----
P
S
-
N
L
-
G
L
S
E
E
E
V
K
E
R
-
V
Y
E
---
A
M
E
-
I
V
G
I
S
K
E
L
-
A
D
K
S
--
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
-
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
-
H
D
K
-
Y
-
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
-
G
K
I
E
L
I
G
T
P
R
E
V
F
-----------------------
115
HHSearch
65.50
34%
-113
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[4-246]
-
A
L
H
I
G
H
L
S
K
S
F
Q
-----
N
----
T
P
V
L
N
D
I
S
L
----
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
----
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
-
F
-----------
S
K
N
T
N
L
P
V
R
----
E
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
-----
L
G
-
N
G
K
-
G
R
T
A
Q
E
R
Q
R
-
I
E
A
---
M
L
E
-
L
T
G
I
S
E
L
A
-
G
-
R
Y
--
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
-
A
-
N
-
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
G
E
---------
93
PsiBlast_CBE
65.30
34%
-111
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[5-246]
--
L
H
I
G
H
L
S
K
S
F
Q
-----
N
----
T
P
V
L
N
D
I
S
L
----
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
----
E
Q
P
D
S
G
E
I
S
L
S
G
-------------
K
T
I
-
F
-----------
S
K
N
T
N
L
P
V
R
----
E
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
-----
L
G
-
N
G
K
G
-
R
T
A
Q
E
R
Q
R
-
I
E
A
---
M
L
E
-
L
T
G
I
S
E
L
A
-
G
-
R
Y
--
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
-
L
-
R
A
N
-
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
G
E
---------
83
PsiBlast_CBE
52.84
33%
-104
- C1 -
2FF7
1
A:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
97
PsiBlast_CBE
52.02
33%
-106
- C1 -
2FGJ
2
HLYBP_ECOLX
A:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
91
PsiBlast_CBE
51.23
33%
-98
- C1 -
3B5J
1
A:
[21-231]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
A
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
98
PsiBlast_CBE
51.11
33%
-101
- C1 -
2FFA
2
A:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
100
PsiBlast_CBE
50.61
33%
-112
- C1 -
1XEF
3
HLYBP_ECOLX
C:
[19-229]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
HDF
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
102
PsiBlast_CBE
50.13
33%
-106
- C1 -
1XEF
3
HLYBP_ECOLX
A:
[19-229]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
88
PsiBlast_CBE
49.90
33%
-103
- C1 -
2FGK
2
HLYBP_ECOLX
B:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
HDF
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
95
PsiBlast_CBE
49.39
33%
-105
- C1 -
2FGJ
2
HLYBP_ECOLX
C:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
HDF
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
90
PsiBlast_CBE
49.20
33%
-97
- C1 -
2FFB
1
A:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
94
PsiBlast_CBE
49.18
33%
-109
- C1 -
2FGJ
2
D:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
HDF
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
85
PsiBlast_CBE
48.95
33%
-101
- C1 -
2PMK
1
A:
[21-231]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
101
PsiBlast_CBE
48.35
33%
-105
- C1 -
1XEF
3
HLYBP_ECOLX
B:
[19-229]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
HDF
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
86
PsiBlast_CBE
48.34
33%
-103
- C1 -
2FGK
2
D:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
HDF
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
96
PsiBlast_CBE
47.89
33%
-105
- C1 -
2FGJ
2
HLYBP_ECOLX
B:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
HDF
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
99
PsiBlast_CBE
47.58
33%
-105
- C1 -
1XEF
3
D:
[19-229]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
HDF
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
87
PsiBlast_CBE
46.60
33%
-102
- C1 -
2FGK
2
HLYBP_ECOLX
C:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
HDF
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------
89
PsiBlast_CBE
46.38
33%
-104
- C1 -
2FGK
2
HLYBP_ECOLX
A:
[25-235]
--------------------------
L
D
N
I
N
L
----
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
----
Y
I
P
E
N
G
Q
V
L
I
D
G
-------------
H
D
L
-
A
-----------
L
A
--
D
P
N
W
L
----
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
A
-----
N
P
-
G
M
S
V
E
K
V
I
Y
A
A
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
-
E
Q
--
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
-
C
-
K
---
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-------------------