@TOME V2.3
(Mar 2018)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : B0VKM8: (2017-10-27 )
MSTPEDISQNKPLLWLMAAACGLCAGVNYYCQPLIHSIQQDFAVTQAQAALTVTFAQVSYALGLLFIVPMGDIVNKAKAIPFLMMLCAVGLFTSAFAVNLPMLWIGTILAGLFSVAAQVLIPLATMTVKPEKTGEIIGFLMSGLLVGILLSTSLAGLFSNLFHWKVVYAISGILMLLLAYTLKSRLPYVMRMKLNYGQIFVSMAQLLKEEKRLLLRALTGAFAFASVSILYSTIALLMTSAHHLPDLFIGLVPLVGIFGALSTRYIGKYADQGYTRLLTWMGCGLFLLSWICFYFGQTLLSAYVIGFALIQLALALVHTSNQSIIFRLRPDAKSRINAIYMTTYFIGGAAGSALGIFAWNRGEWTMTCLAGVGLVVFCILFSMIDAFLQKKQMA

Atome Classification :

(20 SA) ---------.........10........20........30.......-.------40-----.------.--------.-.-.....50........60........70..-.-.....80---........90....------------------..------------.---.100---.........110..-------...-----..120.......-130.........140.......150.......160---.--------------------------..-.-------------..---...170.......180------..-..--------...190-----.-------.-.-.--.--.---.----------------.----------------200-----------------------------------------------..---.-------------------------------------------------.---.---....210......-----.220---....----.-....230.......240----.---...----....250--.-.......260....----...270....----.-----..280.....----..---290...-----.----.-.----------.300.----......310.....-..320.....-..330---------------.-----........340.-.-.....350....------...360-.--.-......370.......380..---------.....390..------------------------------------------------------------
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) ---------MSTPEDISQNKPLLWLMAAACGLCAGVNYYCQPLIHSI-Q------Q------D------F--------A-V-TQAQAALTVTFAQVSYALGLLFIVPMGDI-V-NKAKAIP---FLMMLCAVGLFTSA------------------FA------------V---NL-----PMLWIGTILAGLFS-------VAA-----QVLIPLATMTVK-P--EKTGEIIGFLMSGLLVGILLSTSLAGLFSN-----L--------------------------FH-W-------------KV---VYAISGILMLLLAYTL------KS-RL--------PYVMR------M-------K-L-N--Y--G---Q----------------I----------------F-------------------------------------------------VS---M-------------------------------------------------A---Q---LLKEEKRLLLRAL-----TG-----AFAF----A-SVSILYSTIALLMTSA-----H---HLP----DLFIGL---V-PLVGIFGALSTRYI----GKYADQGYTR----L-----LTWMGCGLFL----LS---WICFYF-----G----Q-T----------LLSAY----VIGFALIQLALALV-HTSNQSIIFR-LRP-----------------D-----AKSRINAIYMTT-Y-FIGGAAGSALGI------FAWNR--G--E-WTMTCLAGVGLVVFCILFSMI---------DAFLQKKQMA------------------------------------------------------------
34 Fugue 76.6416%-135 - C3 - - 3WDO - ? A:[3-455] -------DYKMTP----GERRATWGLGTVFSLRMLGMFMVLPVLTTY-G------M------A------L--------QGA-SEALIGIAIGIYGLTQAVFQIPFGLLSDR-I-GRKPLIV---GGLAVFAAGSVIAA------------------LS------------D---SI-----WGIILGRALQGSGA-------IAA-----AVMALLSDLTRE-Q--NRT-KAMAFIGVSFGITFAIAMVLGPIITH-----K--------------------------LG-L-------------HA---LFWMIAILATTGIALT------IW-VV--------PNSST------H-------V-L-N--RESG---M----------------V----------------K-------------------------------------------------GS---F-------------------------------------------------S---K---VLAEPRLLKLNFG-----IM-----CLHM----L-LMSTFVALPGQLADAG-----F---PAA----EHWKVY---L-ATMLIAFGSVVPFI----IYAEVKRKMK----Q-----VFVFCVGLIV----VA---EIVLWN-----A----Q-T----------QFWQL----VVGVQLFFVAFNLM-EALLPSLISK-ESP-----------------AG----YKGTAMGVYSTS-Q-FLGVAIGGSLG--------GWID--G--M-FDGQGVFLAGAMLAAVWLAVA---------STMKEPPYVSSLRIEIPADIAANEALKVRLLETEGVKEVLIAEEEHSAYVKIDSKVTNRFEVEQAIRQAL
15 HHSearch 76.0614%-145 - C3 - - 3WDO - ? A:[11-385] -------------------RRATWGLGTVFSLRMLGMFMVLPVLTTY-GM-----A------L------Q--------G-A-SEALIGIAIGIYGLTQAVFQIPFGLLSDR-I-GRKPLIV---GGLAVFAAGSVIAA------------------LS------------D---SI-----WGIILGRALQGSGA-------IA------AAVMALLSDLTR-E--QNRTKAMAFIGVSFGITFAIAMVLGPIITH-----K--------------------------LG-L-------------HA---LFWMIAILATTGIALT------IW-VV--------PNSST------H-------VLN-R--E--S---G----------------M----------------V-------------------------------------------------KG---S-------------------------------------------------F---S---KVLAEPRLLKLNF-----GI-----MCLH----M-LLMSTFVALPGQLAD------A---GFP----AAEHWKVYLATMLIAFGSVVPFIIY----AEVKRKMKQV----F-----VFCVGL--IV----VA---EIVLWN-----A----Q-T----------QFWQL----VVGVQLFFVAFNLM-EALLPSLISKESPA-----------------G-----YKGTAMGVYSTS-Q-FLGVAIGGSLGG------WIDGM--F--D-GQGVFLAGAMLAAVWLAVA---------------------------------------------------------------------------------
29 Fugue 73.8914%-169 - C3 - - 2GFP - EMRD_ECOLI A:[9-383] ---------------------LLLMLVLLVAVGQMAQTIYIPAIADM-A------R------D------L--------N-V-REGAVQSVMGAYLLTYGVSQLFYGPISDR-V-GRRPVIL---VGMSIFMLATLVAV------------------TT------------S---SL-----TVLIAASAMQGMGT-------GVG-----GVMARTLPRDLYER--TQLRHANSLLNMGILVSPLLAPLIGGLLDT-----M--------------------------WN-W-------------RA---CYLFLLVLCAGVTFSM------AR-WM--------PETRP------V-------D-A-P--R--T---R----------------L----------------L-------------------------------------------------TS---Y-------------------------------------------------K---T---LFGNSGFNCY-LL-----ML-----IGGL----A-GIAAFEACSGVLMGAV-----L---GLS----SMTVSI---L-FILPIPAAFFGAWF----AGRPNKRFST----L-----MWQSVICCLL----AGLLMWIPDWF-----G----V-M----------NVWTL----LVPAALFFFGAGML-FPLATSGAME-PFP-----------------F-----LAGTAGALVGGL-Q-NIGSGVLASLSA------MLPQT--G--Q-GSLGLLMTLMGLLIVLCWLPL-------------------------------------------------------------------------------
28 HHSearch 72.6414%-164 - C3 - - 4U4V NARK_ECOLI A:[41-433] -------------------------SVPCLLLAFCVWMLFSAVAVNLPK------V------G------F--------N-F-TTDQLFMLTALPSVSGALLRVPYSFMVPI-F-GGRRWTA---FSTGILIIPCVWLG------------------FAVQDTS-------T---PY-----SVFIIISLLCGFAG-------ANF-----ASSMANISFFFP-K--QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAV--------------------------FG-SQGVKQPDGTELYLAN---ASWIWVPFLAIFTIAA------WF-GM--------NDLAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------L---P----VLKRGHLWIMSL-----LY-----LATF----G-SFIGFSAGFAMLSK-------T---QFP----DVQILQ---YAFFGPFIGALARSAG----GALSDRLGGT----R-----VTLVNFILMA----IF---SGLLFLT----LPT--D--QGG-------SFMAFFAVFLALFLTAGLGSGST-FQMISVIFRKLTMDRVKAEGGSDERAMREAAT-----DTAAALGFISAI-G-AIGGFFIPKAFG------SSLAL--T--G-----------------------------------------------------------------------------------------------------
27 HHSearch 72.0114%-173 - C3 - - 4U4T NARK_ECOLI A:[41-433] -------------------------SVPCLLLAFCVWMLFSAVAVNLPK------V------G------F--------N-F-TTDQLFMLTALPSVSGALLRVPYSFMVPI-F-GGRRWTA---FSTGILIIPCVWLG------------------FAVQDTS-------T---PY-----SVFIIISLLCGFAG-------ANF-----ASSMANISFFFP-K--QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAV--------------------------FG-SQGVKQPDGTELYLAN---ASWIWVPFLAIFTIAA------WF-GM--------NDLAT---------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------L---P----VLKRGHLWIMSL-----LY-----LATF----G-SFIGFSAGFAMLSK-------T---QFP----DVQILQ---YAFFGPFIGALARSAG----GALSDRLGGT----R-----VTLVNFILMA----IF---SGLLFLT----LPT--D-GQGG-------SFMAFFAVFLALFLTAGLGSGST-FQMISVIFRKLTMDRVKAEGGSDERAMREAAT-----DTAAALGFISAI-G-AIGGFFIPKAFG------SSLAL--T--G-----------------------------------------------------------------------------------------------------
4 HHSearch 68.8711%-144 - C3 - - 4ZP0 MDFA_ECOLI A:[8-371] -------------------LLFPLCLVLYEFSTYIGNDMIQPGMLAV-V------E------Q------Y--------Q-A-GIDWVPTSMTAYLAGGMFLQWLLGPLSDR-I-GRRPVML---AGVVWFIVTCLAIL------------------LA------------Q---NI-----EQFTLLRFLQGISLC------FIG-----AVGYAAIRESFE-E--AVCIKITALMANVALIAPLLGPLVGAAWIH-----V--------------------------LP-W-------------EG---MFVLFAALAAISFFGL------QR-AM--------PETAT------R-------IGE-KL-S--L---K----------------E----------------L-------------------------------------------------GR---D-------------------------------------------------Y---K---LVLKNGRFVAGAL-----AL-----GFVS----L-PLLAWIAQSPIIIITG-----E---QLS----SYEYGL---LQVPIFGALIAGNLLL----ARLTSRRTVR----S-----LIIMGGWPIM----IG---LLVAAA-----ATVISS-H----------AYLWM----TAGLSIYAFGIGLA-NAGLV-RLTLFASD-----------------M-----SKGTVSAAMGML-Q-MLIFTVGIEISK------HAWLN--G--G-NGL-------------------------------------------------------------------------------------------------
6 HHSearch 67.6514%-164 - C3 - - 2GFP - EMRD_ECOLI A:[16-378] ----------------------------LVAVGQMAQTIYIPAIADM-A------R------D------L--------N-V-REGAVQSVMGAYLLTYGVSQLFYGPISDR-V-GRRPVIL---VGMSIFMLATLVAV------------------TT------------S---SL-----TVLIAASAMQGMGTG------VGG-----VMARTLPRDLYE-R--TQLRHANSLLNMGILVSPLLAPLIGGLLDT-----M--------------------------WN-W-------------RA---CYLFLLVLCAGVTFSM------AR-WM--------PETRP------V-------D-A-P--R--T---R---------------------------------L-------------------------------------------------LT---S-------------------------------------------------Y---K---TLFGNSGFNCYLL-----ML-----IGGL----A-GIAAFEACSGVLMGAV-----L---GLS----SMTVSI---LFILPIPAAFFGAWFA----GRPNKRFSTL----M-----WQSVICCLLA----GL---LMWIPDW----FG---V-M----------NVWTL----LVPAALFFFGAGML-FPLATSGAME-PFP-----------------F-----LAGTAGALVGGL-Q-NIGSGVLASLSA------MLPQTGQG--S-LGLLMTLMGLLIVL--------------------------------------------------------------------------------------
10 HHSearch 65.6914%-137 - C3 - - 5AYO ? A:[11-419] -----------------------TQLLLGRLLTRSGDQAWDFVVPFA-L------L------V------I--------F-PGKLQVAAFYYLIVKIGTFLLTPSSGKWIDT-H-PRIQVVK---WGVWLQFFAILAGM------------------VFFGMLDGLVRAGGR---ESWLL--SVLFIALALSGVMAS------LGSQITDISVGNDLAPSLVA-P--EKLTHFNSWLRRIDLATEVGAPILAGALFA-----F--------------------------HP-E-------------QLPLAGLFLIGLWNLVSFVPE------YF-LL--------RNVIQ------RS------GLKIK--V--L---T-----------------------------------------------------------------------------------------------------------------------------------------------------SDPIFWLILS-----YA-----LLWL----S-VLSPHGVLLAAYLKDE-----M---RLP----ETEIGL---FRGLGAVFGLISTVSF----PYLVRRLGLI----S-----SSRWHLGFQGVTLGIA---VTAFAM-----GS---T-A----------SVYVF----LGCILLSRVGLYGF-SNGEFELRQRLIPE-----------------G-----RRGELNSLSSLT-T-TSATLILFSAGS------LLPQT--E--D-FKYLVYVSLAAVLLANVV----------------------------------------------------------------------------------
14 HHSearch 65.2511%-136 - C3 - - 4IKY ? A:[24-477] ---------------------GLFTLFFTEFWERFSYYGMRAILVYY-M------YYEVSKGG------L--------G-L-DEHLALAIMSIYGALVYMSGIIGGWLADRVF-GTSRAVF---YGGLLIMAGHIALA------------------IP------------G---GV-----AALFVSMALIVLGTG------LLK-----PNVSSIVGDMYK-PGDDRRDAGFSIFYMGINLGAFLAPLVVGTAGM-----K--------------------------YN-F-------------HL---GFGLAAVGMFLGLVVF------VA-TR--------KKNLGLAGTYVPN------P-L-T--PAEK---K----------------K----------------AAAIMAVGAVVIAVLLAILIPNGWFTVETFISLVGILGIIIPIIYFVVMYRS---P-------------------------------------------------KTTAE---ERSRVIAYIPLFV-----AS-----AMFW----A-IQQQGSTILANYADKR-----T---QLDVAGIHLSPAW---FQSLNPLFIIILAPVF----AWMWVKLGKR----QPTIPQKFALGLLFAG----LS---FIVILV-----P----G-HLSGGGLV---HPIWL----VLSYFIVVLGELCL-SPVGLSATTKLAPA-----------------A-----FSAQTMSLWFLS-N-AAAQAINAQLVR------FYTPE-----N-ETAYFGTIGGAALVL-------------------------------------------------------------------------------------
16 HHSearch 64.0711%-133 - C3 - - 4IKV ? A:[23-477] --------------------KGLFTLFFTEFWERFSYYGMRAILVYY-M------Y------YEVSKGGL--------G-L-DEHLALAIMSIYGALVYMSGIIGGWLADRVF-GTSRAVF---YGGLLIMAGHIALA------------------IP------------G---GV-----AALFVSMALIVLGTG------LLK-----PNVSSIVGDMYK-PGDDRRDAGFSIFYMGINLGAFLAPLVVGTAGM-----K--------------------------YN-F-------------HL---GFGLAAVGMFLGLVVF------VA-TR--------KKNLG------LAGTYVPNP-L-TPAE--K---K----------------K----------------AAAIMAVGAVVIAVLLAILIPNGWFTVETFISLVGILGIIIPIIYFVVMYRS---P-------------------------------------------------KTTAE---ERSRVIAYIPLFV-----AS-----AMFW----A-IQEQGSTILANYADKR-----T---QLDVAGIHLSPAW---FQSLNPLFIIILAPVF----AWMWVKLGKR----QPTIPQKFALGLLFAG----LS---FIVILV-----P----G-HLSGGGLV---HPIWL----VLSYFIVVLGELCL-SPVGLSATTKLAPA-----------------A-----FSAQTMSLWFLS-N-AAAQAINAQLVR------FYTPE-----N-ETAYFGTIGGAALVL-------------------------------------------------------------------------------------
26 HHSearch 63.7714%-134 - C3 - - 4W6V - ? A:[20-490] ----------------------LSGLFLSEMWERFSFYGIRPLLILF-MAATVFDG------G------M--------G-L-PREQASAIVGIFAGSMYLAALPGGLLADN-WLGQQRAVW---YGSILIALGHLSIA------------------LS------------AFF-GN-----DLFFIGLVFIVLGTG------LFK-----TCISVMVGTLYK-PGDARRDGGFSLFYMGINMGSFIAPLLSGWLLR-----T--------------------------HG-W-------------HW---GFGIGGIGMLVALLIF------RGFAI--------PAMKR------YD------AEVGL--D--SSWNK----------------PT-------------------------------------------------------------------GR-WVTAIMAVVVVIIALISQGVIPINPVMIASLLVYVIAASVTLYFIYLFAFA---K---MSRKDRARLLVCFILLV-SA-----AFFW----S-AFEQKPTSFNLFANDYTDRMVM---GFE-----IPTVW---FQSINALFIILLAPVF----SWA-------PSSIT-----KFVIGILCAA----AG---FAVMMY-----A----A-QHVLSSGGAGVSPLWL----VMSILLLTLGELCL-SPIGLATMTLLAPD-----------------R-----MRGQVMGLWFCA-S-SLGNLAAGLIGG------HVKAD--QLDM-LPTLFARCSIALVICAAV----------------------------------------------------------------------------------
9 HHSearch 63.0212%-161 - C3 - - 3O7Q FUCP_ECOLI A:[31-434] -------------------------LCSLFFLWAVANNLNDILLPQF-Q------Q------A------F--------T-L-TNFQAGLIQSAFYFGYFIIPIPAGILMKK-L-SYKAGII---TGLFLYALGAALFW------------------PA------------AEIMNY-----TLFLVGLFIIAAGLG------CLE-----TAANPFVTVLGP-E--SSGHFRLNLAQTFNSFGAIIAVVFGQSLIL-----SNVPHQSQDVLDKMSPEQLSAYKHSLVLS-V-------------QT---PYMIIVAIVLLVALLI------ML--T--------KFPAL------QS------D-N-H--S--DAKQG----------------S----------------F-------------------------------------------------SA---S-------------------------------------------------L---S---RLARIRHWRWAVL-----AQ-----FCYV----G-AQTACWSYLIRYAVEEI----P---GMT----AGFAAN---YLTGTMVCFFIGRFTG----TWLISRFAPH----K-----VLAAYALIAM----AL---CLISAF-----A----G------------GHV-G----LIALTLCSAFMSIQ-YPTIFSLGIKNLGQ-----------------D------TKYGSSF-IVM-T-IIGGGIVTPVMG------FVSDA--A--GNIPTAELIPALCFAVIFIFARF---------RSQ-------------------------------------------------------------------
8 HHSearch 62.6514% - - C3 - - 4LDS - ? A:[11-415] ------------------------LGALGGLLYGYDNGVISGALLFI-H------K------D------I--------P-L-NSTTEGIVVSSMLIGAIVGAGSSGPLADK-L-GRRRLVM---LIAIVFIIGALILA------------------AS------------T---NL-----ALLIIGRLIIGLAVG------GSM-----STVPVYLSEMAP-T--EYRGSLGSLNQLMITIGILAAYLVNYAFAD-----I--------------------------EG-W-------------RW---MLGLAVVPSVILLVGI-------Y-FM--------PESPR------WLLE----N-R-N--E--E---AARQVMKITYDDSEIDKELKEMKE----------I-------------------------------------------------NAISES-------------------------------------------------T---W---TVIKSPWLGRILI-----VG-----CIFAIFQQFIGINAVIFYSSSIFA-K-----A---GLG----EAASIL---GSVGIGTINVLVTIVA----IFVVDKIDRK----K-----LLVGGNIGMI----AS---LLIMAILIWTIGI---A-S----------SAWII----IVCLSLFIVFFGISWGPVLWVMLPELFPM-----------------R-----ARGAATGISALV-L-NIGTLIVSLFFP------ILSDA--L--S-TEWVFLIFAFIGVLAM------------------------------------------------------------------------------------
31 Fugue 61.6611%-154 - C3 - - 1PV6 - LACY_ECOLI A:[1-417] -------------MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWL-H------D------I------N--------H-I-SKSDTGIIFAAISLFSLLFQPLFGLLSDK-L-GLRKYLL---WIITGMLVMFAPFF------------------IF------------I---FG-----PLLQYNILVGSIVGGIYLGFCFNA-----GAPAVEAFIEKV-S--RRSNFEFGRARMFGCVGWALGASIVGIMFT-----I--------------------------NN-Q-------------FV---FWLGSGCALILAVLLFFAKTDAPS-SA--------TVANA------V-------G-A-N--H--S---A----------------F----------------S-------------------------------------------------LK---L-------------------------------------------------A---L---ELFRQPKLWFLSL-----YV-----IGVS----C-TYDVFDQQFANFFTSF-----F---ATG----EQGTRV---F-GYVTTMGELLNASIMFFAPLIINRIGGK----N-----ALLLAGTIMS----VR---IIGSSF-----A----T-S----------ALEVV----ILKTLHMFEVPFLL-VGCFKYITSQ-FEV-----------------R-----FSATIYLVCFCFFK-QLAMIFMSVLAG------NMYES--I--G-FQGAYLVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA------------------------------------------------------------
23 HHSearch 60.7013%-150 - C3 - - 4GBY XYLE_ECOLI A:[18-455] --------------------------TLGGLLFGYDTAVISGTVESL-N------T------V------FVAPQNLSES-A-ANSLLGFCVASALIGCIIGGALGGYCSNR-F-GRRDSLK---IAAVLFFISGVGSAWPELGFTSINPDNTVPVYLA------------G---YV-----PEFVIYRIIGGIGVG------LAS-----MLSPMYIAELAP-A--HIRGKLVSFNQFAIIFGQLLVYCVNYFIAR-----SGDASWLNT------------------DG-W-------------RY---MFASECIPALLFLML-------LY-TV--------PESPR------WLMS----R-G-K--Q--E---Q----------------AEGILRKIMGNTLATQAV-------------------------------------------------QE---I-------------------------------------------------K---HSLDHGRKTGGRLLMFGVGVIVIGVMLSIFQQF----V-GINVVLYYAPEVFK-T-----L---GAS----TDIALL---QTIIVGVINLTFTVLA----IMTVDKFGRK----P-----LQIIGALGMA----IG---MFSLGT-----AFYT-QAP----------GIVAL----LSMLFYVAAFAMSW-GPVCWVLLSEIFPN-----------------A-----IRGKALAIAVAA-Q-WLANYFVSWTFPMMDKNSWLVAH--F--H-NGFSYWIYGCMGVLA-------------------------------------------------------------------------------------
11 HHSearch 60.2914%-136 - C3 - - 5AYN ? A:[11-419] -----------------------TQLLLGRLLTRSGDQAWDFVVPFA-L------L------V------I--------F-PGKLQVAAFYYLIVKIGTFLLTPSSGKWIDT-H-PRIQVVK---WGVWLQFFAILAGM------------------VFFGMLDGLVRAGGR---ESWLL--SVLFIALALSGVMAS------LGSQITDISVGNDLAPSLVA-P--EKLTHFNSWLRRIDLATEVGAPILAGALF----------------------------------------------------PLAGLFLIGLWNLVSFVPE------YF-LL--------RNVIQ------RS------GLKIK--V--L---TEA----------------------------------------------------------------------------------I---N-------------------------------------------------L---R---GSFSDPIFWLILS-----YA-----LLWL----S-VLSPHGVLLAAYLKDE-----M---RLP----ETEIGL---FRGLGAVFGLISTVSF----PYLVRRLGLI----S-----SSRWHLGFQGVTLGIA---VTAFAM-----GS---T-A----------SVYVF----LGCILLSRVGLYGF-SNGEFELRQRLIPE-----------------G-----RRGELNSLSSLT-T-TSATLILFSAGS------LLPQT--E--D-FKYLVYVSLAAVLLANVV----------------------------------------------------------------------------------
13 HHSearch 59.4412%-154 - C3 - - 2CFQ - LACY_ECOLI A:[10-393] -----------------------WMFGLFFFFYFFIMGAYFPFFPIW-L------H------D------IN-------H-I-SKSDTGIIFAAISLFSLLFQPLFGLLSDK-L-GLRKYLLWIITGMLVMFAPFFIFI------------------FG------------P---LLQ----YNILVGSIVGGIYLG------FCF-----NAGAPAVEAFIE-KVSRRSNFEFGRARMFGCVGWALGASIVGIMFT--------------------------------IN-N-------------QF---VFWLGSGCALILAVLL------FF-AK--------TDAPS------SA------T-V-AN-AVGA---NHSA-------------F----------------S-------------------------------------------------LK---L-------------------------------------------------A---L---ELFRQPKLWFLSL-----YV-----IGVS----C-TYDVFDQQFANFFTSF-----FATGEQG----TRVFGY---VTTMGELLNASIMFFA----PLIINRIGGK----N-----ALLLAGTIMS----VR---IIGSSF-----A----T------------SALEV----VILKTLHMFEVPFL-LVGCFKYITSQFEV-----------------R-----FSATIYLVCFCF-FKQLAMIFMSVLAG------NMYES--I--G-FQGAYLVLGLVALGFT------------------------------------------------------------------------------------
25 HHSearch 59.2013%-147 - C3 - - 4GC0 XYLE_ECOLI A:[18-455] --------------------------TLGGLLFGYDTAVISGTVESL-N------T------V------FVAPQNLSES-A-ANSLLGFCVASALIGCIIGGALGGYCSNR-F-GRRDSLK---IAAVLFFISGVGSAWPELGFTSINPDNTVPVYLA------------G---YV-----PEFVIYRIIGGIGVG------LAS-----MLSPMYIAELAP-A--HIRGKLVSFNQFAIIFGQLLVYCVNYFIAR-----SGDASWLNT------------------DG-W-------------RY---MFASECIPALLFLML-------LY-TV--------PESPR------WLMS----R-G-K--Q--E---Q----------------AEGILRKIMGNTLATQAV-------------------------------------------------QE---I-------------------------------------------------K---HSLDHGRKTGGRLLMFGVGVIVIGVMLSIFQQF----V-GINVVLYYAPEVFK-T-----L---GAS----TDIALL---QTIIVGVINLTFTVLA----IMTVDKFGRK----P-----LQIIGALGMA----IG---MFSLGT-----AFYT-QAP----------GIVAL----LSMLFYVAAFAMSW-GPVCWVLLSEIFPN-----------------A-----IRGKALAIAVAA-Q-WLANYFVSWTFPMMDKNSWLVAH--F--H-NGFSYWIYGCMGVLA-------------------------------------------------------------------------------------
12 HHSearch 58.8812%-164 - C3 - - 1PV7 LACY_ECOLI A:[10-393] -----------------------WMFGLFFFFYFFIMGAYFPFFPIW-L------H------D------IN-------H-I-SKSDTGIIFAAISLFSLLFQPLFGLLSDK-L-GLRKYLLWIITGMLVMFAPFFIFI------------------FG------------P---LLQ----YNILVGSIVGGIYLG------FCF-----NAGAPAVEAFIE-KVSRRSNFEFGRARMFGCVGWALGASIVGIMFT--------------------------------IN-N-------------QF---VFWLGSGCALILAVLL------FF-AK--------TDAPS------SA------T-V-AN-AVGA---NHSA-------------F----------------S-------------------------------------------------LK---L-------------------------------------------------A---L---ELFRQPKLWFLSL-----YV-----IGVS----C-TYDVFDQQFANFFTSF-----FATGEQG----TRVFGY---VTTMGELLNASIMFFA----PLIINRIGGK----N-----ALLLAGTIMS----VR---IIGSSF-----A----T------------SALEV----VILKTLHMFEVPFL-LVGCFKYITSQFEV-----------------R-----FSATIYLVCFCF-FKQLAMIFMSVLAG------NMYES--I--G-FQGAYLVLGLVALGFT------------------------------------------------------------------------------------
30 Fugue 55.8011%-129 * C3 * - 1PW4 - GLPT_ECOLI A:[5-451] FKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALA-M------PYLV---E------Q--------G-F-SRGDLGFALSGISIAYGFSKFIMGSVSDR-S-NPRVFLP---AGLILAAAVMLFMG------------------FV------------P---WATSSIAVMFVLLFLCGWFQG-------MGW-----PPCGRTMVHWWS-Q--KERGGIVSVWNCAHNVGGGIPPLLFLLGMA-----W--------------------------FNDW-------------HA---ALYMPAFCAILVALFA------FA-MMRDTPQSCGLPPIE------E-------Y-K-N--D--T---A----------------K----------------Q-------------------------------------------------IF---M-------------------------------------------------Q---Y---VLPNKLLWYIAIA-----NV-----FVYL----L-RYGILDWSPTYLKEVK-----H---FAL----DKSSWA---Y-FLYEYAGIPGTLLC----GWMSDKVFRG----N-----RGATGVFFMT----LV---TIATIV-----Y----W-M----------NPAGN----PTVDMICMIVIGFL-IYGPVMLIGL-HAL-----------------ELAPKKAAGTAAGFTGLF-G-YLGGSVAASAIV------GYTVD--F--F-GWDGGFMVMIGGSILAVILLI---------VVMIGEKRRHEQLLQELVP---------------------------------------------------