@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VT30: (2017-12-11 )
MLLEFTKMHGLGNDFMVVDLISQRAYLDTATIQRLADRHFGVGFDQLLIVEPPDVPEADFKYRIFNADGSEVEQCGNGVRCFARFVHERHLTNKTNITVQTKAGIVKPELGQNGWVRVNMGYPKFLPNEIPFVADEPEALYTLELANDQNISIDVVNMGNPHAVTIVPDVLTADVAGIGPQVESHKRFPERINAGFMQVIDDKHVRLRVFERCVGETLACGTGACAAAVSGMRRGLLANSVEVELAGGKLQIEWQEGDVVWMTGPTTHVYDGRLDLRYFQG
Atome Classification :
(22 SA)
.........10........-20........30........40...--....-.50....--------------....60....-----....70........80.......-.90........100.......110----.----......120.......130-.-..-.....140.......-150.......160.....----..170.....--....180....-.--..190.......200.......210.......220...-....230.-......240.......250..-.-.-.-..260.......270.......280
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
ML
L
E
F
T
KMHGLGN
D
F
M
V
V
D
-
L
I
SQRAYL
D
T
A
T
I
Q
R
L
A
D
R
HFGVGF--
D
Q
L
L
-
I
VEPPDV--------------PEAD
F
K
Y
R
I
F-----NAD
G
S
E
V
E
Q
CG
N
G
V
R
C
F
A
R
F
V
H
E
-
R
HLTNKT
N
I
T
V
Q
TKAGIVKPELGQ----N----
G
W
V
R
V
NMGYPKFLPNEIP--F-VA-DEPE
A
L
Y
T
L
E
LANDQ-
N
I
S
I
D
V
V
NMGNP
H
A
V
T
IV----
P
D
V
--
L
T
A
D
V--AGIGPQ
V
E
S
HK-R--
F
P
E
R
I
N
A
G
F
M
Q
V
IDDK
H
V
R
L
R
V
F
E
R
C
VGETLACG
T
G
A
C
-
A
A
A
V
S
G
M
R
-
R
G
LLAN
S
V
E
V
E
LAG
G
K
L
Q
I
E
W-Q-E-G-
D
V
V
W
M
TGPT
T
H
V
YDG
R
L
D
L
R
YFQG
1
PsiBlast_PDB
95.01
98%
-119
- C4 -
-
5HA4
2
DAPF_ACIB3
A:
[3-282]
M
L
L
E
F
T
K
M
H
G
L
G
N
D
F
M
V
V
D
-
L
I
S
Q
R
A
Y
L
D
T
A
T
I
Q
R
L
A
D
R
H
F
G
V
G
F
--
D
Q
L
L
-
I
V
E
P
P
D
V
--------------
P
E
A
D
F
K
Y
R
I
F
-----
N
A
D
G
S
E
V
E
Q
C
G
N
G
V
R
C
F
A
R
F
V
H
E
-
R
H
L
T
N
K
T
N
I
T
V
Q
T
K
A
G
I
V
K
P
E
L
G
Q
----
N
----
G
W
V
R
V
N
M
G
Y
P
K
F
L
P
N
E
I
P
--
F
-
V
A
-
E
E
P
E
A
L
Y
T
L
E
L
A
N
D
Q
-
N
I
S
I
D
V
V
N
M
G
N
P
H
A
V
T
I
V
----
P
D
V
--
L
T
A
D
V
--
A
G
I
G
P
Q
V
E
S
H
K
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
V
I
D
D
K
H
V
R
L
R
V
F
E
R
G
V
G
E
T
L
A
C
G
T
G
A
C
-
A
A
A
V
S
G
M
R
-
R
G
L
L
A
N
S
V
E
V
E
L
A
G
G
K
L
Q
I
E
W
-
Q
-
E
-
G
-
D
V
V
W
M
T
G
P
T
T
H
V
Y
D
G
R
L
D
L
R
Y
F
Q
-
45
HHSearch
88.22
97%
-56
* C4 *
-
5HA4
-
DAPF_ACIB3
B:
[3-282]
M
L
L
E
F
T
K
M
H
G
L
G
N
D
F
M
V
V
D
-
L
I
S
Q
R
A
Y
L
D
T
A
T
I
Q
R
L
A
D
R
H
F
G
V
G
F
--
D
Q
L
L
-
I
V
E
P
P
D
V
--------------
P
E
A
D
F
K
Y
R
I
F
-----
N
A
D
G
S
E
V
E
Q
C
G
N
G
V
R
C
F
A
R
F
V
H
E
-
R
H
L
T
N
K
T
N
I
T
V
Q
T
K
A
G
I
V
K
P
E
L
G
Q
----
N
----
G
W
V
R
V
N
M
G
Y
P
K
F
L
P
N
E
I
P
--
F
V
A
E
-
E
P
E
A
L
-
Y
T
L
E
L
A
N
D
Q
-
N
I
S
I
D
V
V
N
M
G
N
P
H
A
V
T
I
V
----
P
D
V
--
L
T
A
D
V
--
A
G
I
G
P
Q
V
E
S
H
K
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
V
I
D
D
K
H
V
R
L
R
V
F
E
R
G
V
G
E
T
L
A
C
G
T
G
A
C
-
A
A
A
V
S
G
M
R
-
R
G
L
L
A
N
S
V
E
V
E
L
A
G
G
K
L
Q
I
E
W
-
Q
-
E
-
G
-
D
V
V
W
M
T
G
P
T
T
H
V
Y
D
G
R
L
D
L
R
Y
F
Q
-
44
HHSearch
87.26
97%
-58
- C4 -
-
5HA4
2
DAPF_ACIB3
A:
[3-282]
M
L
L
E
F
T
K
M
H
G
L
G
N
D
F
M
V
V
D
-
L
I
S
Q
R
A
Y
L
D
T
A
T
I
Q
R
L
A
D
R
H
F
G
V
G
F
--
D
Q
L
L
-
I
V
E
P
P
D
V
--------------
P
E
A
D
F
K
Y
R
I
F
-----
N
A
D
G
S
E
V
E
Q
C
G
N
G
V
R
C
F
A
R
F
V
H
E
-
R
H
L
T
N
K
T
N
I
T
V
Q
T
K
A
G
I
V
K
P
E
L
G
Q
----
N
----
G
W
V
R
V
N
M
G
Y
P
K
F
L
P
N
E
I
P
--
F
V
A
E
-
E
P
E
A
L
-
Y
T
L
E
L
A
N
D
Q
-
N
I
S
I
D
V
V
N
M
G
N
P
H
A
V
T
I
V
----
P
D
V
--
L
T
A
D
V
--
A
G
I
G
P
Q
V
E
S
H
K
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
V
I
D
D
K
H
V
R
L
R
V
F
E
R
G
V
G
E
T
L
A
C
G
T
G
A
C
-
A
A
A
V
S
G
M
R
-
R
G
L
L
A
N
S
V
E
V
E
L
A
G
G
K
L
Q
I
E
W
-
Q
-
E
-
G
-
D
V
V
W
M
T
G
P
T
T
H
V
Y
D
G
R
L
D
L
R
Y
F
Q
-
2
PsiBlast_PDB
83.53
58%
-134
- C4 -
-
4IJZ
-
DAPF_ECOLI
A:
[1-270]
--
M
Q
F
S
K
M
H
G
L
G
N
D
F
M
V
V
D
-
A
V
T
Q
N
V
F
F
S
P
E
L
I
R
R
L
A
D
R
H
L
G
V
G
F
--
D
Q
L
L
-
V
V
E
P
P
Y
D
--------------
P
E
L
D
F
H
Y
R
I
F
-----
N
A
D
G
S
E
V
A
Q
C
G
N
G
A
R
C
F
A
R
F
V
R
L
-
K
G
L
T
N
K
R
D
I
R
V
S
T
A
N
G
R
M
V
L
T
V
T
D
----
D
----
D
L
V
R
V
N
M
G
E
P
N
F
E
P
S
A
V
P
--
F
-
R
A
-
N
K
A
E
K
T
Y
I
M
R
A
A
-
E
Q
-
T
I
L
C
G
V
V
S
M
G
N
P
H
C
V
I
Q
V
----
D
D
V
--
D
T
A
A
V
--
E
T
L
G
P
V
L
E
S
H
E
-
R
--
F
P
E
R
A
N
I
G
F
M
Q
V
V
K
R
E
H
I
R
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
A
C
-
A
A
V
A
V
G
I
Q
-
Q
G
L
L
A
E
E
V
R
V
E
L
P
G
G
R
L
D
I
A
W
-
K
G
P
-
G
-
H
P
L
Y
M
T
G
P
A
V
H
V
Y
D
G
---------
3
PsiBlast_PDB
82.73
57%
-131
- C4 -
-
4IK0
-
DAPF_ECOLI
A:
[1-270]
--
M
Q
F
S
K
M
H
G
L
G
N
D
F
M
V
V
D
-
A
V
T
Q
N
V
F
F
S
P
E
L
I
R
R
L
A
D
R
H
L
G
V
G
F
--
D
Q
L
L
-
V
V
E
P
P
Y
D
--------------
P
E
L
D
F
H
Y
R
I
F
-----
N
A
D
G
S
E
V
A
Q
C
G
N
G
A
R
C
F
A
R
F
V
R
L
-
K
G
L
T
N
K
R
D
I
R
V
S
T
A
N
G
R
M
V
L
T
V
T
D
----
D
----
D
L
V
R
V
N
M
G
E
P
N
F
E
P
S
A
V
P
--
F
-
R
A
-
N
K
A
E
K
T
Y
I
M
R
A
A
-
E
Q
-
T
I
L
C
G
V
V
S
M
G
N
P
H
C
V
I
Q
V
----
D
D
V
--
D
T
A
A
V
--
E
T
L
G
P
V
L
E
S
H
E
-
R
--
F
P
E
R
A
N
I
G
F
M
Q
V
V
K
R
E
H
I
R
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
A
C
-
A
A
V
A
V
G
I
Q
-
Q
G
L
L
A
E
E
V
R
V
E
L
P
G
G
R
L
D
I
A
W
-
K
G
P
-
G
-
H
P
L
Y
M
T
G
P
A
V
H
V
A
D
G
---------
9
PsiBlast_PDB
81.18
54%
-117
- C4 -
-
2Q9J
1
DAPF_HAEIN
A:
[1-274]
--
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
-
G
V
T
Q
N
V
F
F
T
P
E
T
I
R
R
L
A
N
R
H
C
G
I
G
F
--
D
Q
L
L
-
I
V
E
A
P
Y
D
--------------
P
E
L
D
F
H
Y
R
I
F
-----
N
A
D
G
S
E
V
S
Q
C
G
N
G
A
R
C
F
A
R
F
V
T
L
-
K
G
L
T
N
K
K
D
I
S
V
S
T
Q
K
G
N
M
V
L
T
V
K
D
----
D
----
N
Q
I
R
V
N
M
G
E
P
I
W
E
P
A
K
I
P
--
F
-
T
A
-
N
K
F
E
K
N
Y
I
L
R
-
T
D
I
Q
-
T
V
L
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
----
D
D
I
--
Q
T
A
N
V
--
E
Q
L
G
P
L
L
E
S
H
E
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
S
G
S
G
A
C
-
A
A
V
A
V
G
I
M
-
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
E
W
-
N
-
G
V
G
-
H
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
L
-----
7
PsiBlast_PDB
81.10
55%
-122
- C4 -
-
1BWZ
-
DAPF_HAEIN
A:
[1-274]
--
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
-
G
V
T
Q
N
V
F
F
T
P
E
T
I
R
R
L
A
N
R
H
C
G
I
G
F
--
D
Q
L
L
-
I
V
E
A
P
Y
D
--------------
P
E
L
D
F
H
Y
R
I
F
-----
N
A
D
G
S
E
V
S
Q
C
G
N
G
A
R
C
F
A
R
F
V
T
L
-
K
G
L
T
N
K
K
D
I
S
V
S
T
Q
K
G
N
M
V
L
T
V
K
D
----
M
----
N
Q
I
R
V
N
M
G
E
P
I
W
E
P
A
K
I
P
--
F
-
T
A
-
N
K
F
E
K
N
Y
I
L
R
-
T
D
I
Q
-
T
V
L
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
----
D
D
I
--
Q
T
A
N
V
--
E
Q
L
G
P
L
L
E
S
H
E
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
A
C
-
A
A
V
A
V
G
I
M
-
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
E
W
-
N
-
G
V
G
-
H
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
L
-----
5
PsiBlast_PDB
81.07
55%
-105
- C4 -
-
2GKE
5
DAPF_HAEIN
A:
[1-274]
--
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
-
G
V
T
Q
N
V
F
F
T
P
E
T
I
R
R
L
A
N
R
H
C
G
I
G
F
--
D
Q
L
L
-
I
V
E
A
P
Y
D
--------------
P
E
L
D
F
H
Y
R
I
F
-----
N
A
D
G
S
E
V
S
Q
C
G
N
G
A
R
C
F
A
R
F
V
T
L
-
K
G
L
T
N
K
K
D
I
S
V
S
T
Q
K
G
N
M
V
L
T
V
K
D
----
D
----
N
Q
I
R
V
N
M
G
E
P
I
W
E
P
A
K
I
P
--
F
-
T
A
-
N
K
F
E
K
N
Y
I
L
R
-
T
D
I
Q
-
T
V
L
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
----
D
D
I
--
Q
T
A
N
V
--
E
Q
L
G
P
L
L
E
S
H
E
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
A
C
-
A
A
V
A
V
G
I
M
-
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
E
W
-
N
-
G
V
G
-
H
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
L
-----
8
PsiBlast_PDB
80.93
54%
-114
- C4 -
-
2Q9H
3
DAPF_HAEIN
A:
[1-274]
--
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
-
G
V
T
Q
N
V
F
F
T
P
E
T
I
R
R
L
A
N
R
H
C
G
I
G
F
--
D
Q
L
L
-
I
V
E
A
P
Y
D
--------------
P
E
L
D
F
H
Y
R
I
F
-----
N
A
D
G
S
E
V
S
Q
S
G
N
G
A
R
C
F
A
R
F
V
T
L
-
K
G
L
T
N
K
K
D
I
S
V
S
T
Q
K
G
N
M
V
L
T
V
K
D
----
D
----
N
Q
I
R
V
N
M
G
E
P
I
W
E
P
A
K
I
P
--
F
-
T
A
-
N
K
F
E
K
N
Y
I
L
R
-
T
D
I
Q
-
T
V
L
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
----
D
D
I
--
Q
T
A
N
V
--
E
Q
L
G
P
L
L
E
S
H
E
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
A
C
-
A
A
V
A
V
G
I
M
-
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
E
W
-
N
-
G
V
G
-
H
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
L
-----
6
PsiBlast_PDB
80.82
55%
-107
- C4 -
-
2GKJ
3
DAPF_HAEIN
A:
[1-274]
--
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
-
G
V
T
Q
N
V
F
F
T
P
E
T
I
R
R
L
A
N
R
H
C
G
I
G
F
--
D
Q
L
L
-
I
V
E
A
P
Y
D
--------------
P
E
L
D
F
H
Y
R
I
F
-----
N
A
D
G
S
E
V
S
Q
C
G
N
G
A
R
C
F
A
R
F
V
T
L
-
K
G
L
T
N
K
K
D
I
S
V
S
T
Q
K
G
N
M
V
L
T
V
K
D
----
D
----
N
Q
I
R
V
N
M
G
E
P
I
W
E
P
A
K
I
P
--
F
-
T
A
-
N
K
F
E
K
N
Y
I
L
R
-
T
D
I
Q
-
T
V
L
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
----
D
D
I
--
Q
T
A
N
V
--
E
Q
L
G
P
L
L
E
S
H
E
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
A
C
-
A
A
V
A
V
G
I
M
-
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
E
W
-
N
-
G
V
G
-
H
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
L
-----
46
HHSearch
71.10
53%
-43
- C4 -
-
2GKE
5
DAPF_HAEIN
A:
[1-274]
--
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
-
G
V
T
Q
N
V
F
F
T
P
E
T
I
R
R
L
A
N
R
H
C
G
I
G
F
---
D
Q
L
-
L
I
V
E
A
P
Y
D-------------
P
E
L
D
F
H
Y
R
I
F
-----
N
A
D
G
S
E
V
S
Q
C
G
N
G
A
R
C
F
A
R
F
V
T
L
-
K
G
L
T
N
K
K
D
I
S
V
S
T
Q
K
G
N
M
V
L
T
V
K
D
----
D
----
N
Q
I
R
V
N
M
G
E
P
I
W
E
P
A
K
I
P
--
F
-
T
A
N
K
F
E
K
-
N
Y
I
L
R
T
D
-
I
Q
-
T
V
L
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
----
D
D
I
--
Q
T
A
N
V
--
E
Q
L
G
P
L
L
E
S
H
E
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
A
C
-
A
A
V
A
V
G
I
M
-
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
E
W
-
N
-
G
-
V
G
H
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
L
-----
4
PsiBlast_PDB
68.35
55%
-
- C4 -
-
1GQZ
-
DAPF_HAEIN
A:
[1-274]
--
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
-
G
V
T
Q
N
V
F
F
T
P
E
T
I
R
R
L
A
N
R
H
C
G
I
G
F
--
D
Q
L
L
-
I
V
E
A
P
Y
D
--------------
P
E
L
D
F
H
Y
R
I
F
-----
N
A
D
G
S
E
V
S
Q
C
G
N
G
A
R
C
F
A
R
F
V
T
L
-
K
G
L
T
N
K
K
D
I
S
V
S
T
Q
K
G
N
M
V
L
T
V
K
D
----
D
----
N
Q
I
R
V
N
M
G
E
P
I
W
E
P
A
K
I
P
--
F
-
T
A
-
N
K
F
E
K
N
Y
I
L
R
-
T
D
I
Q
-
T
V
L
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
----
D
D
I
--
Q
T
A
N
V
--
E
Q
L
G
P
L
L
E
S
H
E
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
A
C
-
A
A
V
A
V
G
I
M
-
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
E
W
-
N
-
G
V
G
-
H
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
L
-----
47
HHSearch
65.11
51%
-11
- C4 -
-
2Q9H
3
DAPF_HAEIN
A:
[1-274]
--
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
-
G
V
T
Q
N
V
F
F
T
P
E
T
I
R
R
L
A
N
R
---
H
C
G
IG
F
D
Q
L
-
L
I
V
E
A
P
Y
D-------------
P
E
L
D
F
H
Y
R
I
F
-----
N
A
D
G
S
E
V
S
Q
S
G
N
G
A
R
C
F
A
R
F
V
T
L
-
K
G
L
T
N
K
K
D
I
S
V
S
T
Q
K
G
N
M
V
L
T
V
K
D
----
D
----
N
Q
I
R
V
N
M
G
E
P
I
W
E
P
A
K
I
P
--
F
-
T
A
N
K
F
E
K
N
-
Y
I
L
R
T
D
-
I
Q
-
T
V
L
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
----
D
D
I
--
Q
T
A
N
V
--
E
Q
L
G
P
L
L
E
S
H
E
-
R
--
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
A
C
-
A
A
V
A
V
G
I
M
-
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
E
W
-
N
-
G
-
V
G
H
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
L
-----
11
PsiBlast_PDB
62.71
42%
-12
- C4 -
-
3EKM
1
DAPF_ARATH
A:
[26-307]
-
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
A
--
D
G
V
--
I
F
A
M
P
G
V
--------------
N
G
T
D
Y
A
M
R
I
F
-----
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
A
E
L
E
N
L
Q
G
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
D
----
D
----
G
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
TK
L
-
S
G
-
N
K
G
E
A
V
V
E
A
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
KKGG
P
N
L
--
K
V
D
D
L
NL
P
E
I
G
P
K
F
E
H
H
E
-
M
--
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
A
C
-
A
L
V
V
A
A
V
L
-
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
-
E
-
D
-
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
---------
27
PsiBlast_CBE
62.46
42%
-13
- C4 -
-
3EKM
1
DAPF_ARATH
C:
[26-307]
-
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
A
--
D
G
V
--
I
F
A
M
P
G
V
--------------
N
G
T
D
Y
A
M
R
I
F
-----
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
A
E
L
E
N
L
Q
G
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
D
----
D
----
G
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
TK
L
-
S
G
-
N
K
G
E
A
V
V
E
A
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
KKGG
P
N
L
--
K
V
D
D
L
NL
P
E
I
G
P
K
F
E
H
H
E
-
M
--
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
A
C
-
A
L
V
V
A
A
V
L
-
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
-
E
-
D
-
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
---------
26
PsiBlast_CBE
62.25
42%
-14
- C4 -
-
3EKM
1
DAPF_ARATH
D:
[26-307]
-
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
A
--
D
G
V
--
I
F
A
M
P
G
V
--------------
N
G
T
D
Y
A
M
R
I
F
-----
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
A
E
L
E
N
L
Q
G
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
D
----
D
----
G
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
TK
L
-
S
G
-
N
K
G
E
A
V
V
E
A
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
KKGG
P
N
L
--
K
V
D
D
L
NL
P
E
I
G
P
K
F
E
H
H
E
-
M
--
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
A
C
-
A
L
V
V
A
A
V
L
-
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
-
E
-
D
-
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
---------
33
PsiBlast_CBE
62.20
42%
-10
- C4 -
-
3EJX
1
DAPF_ARATH
B:
[26-307]
-
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
A
--
D
G
V
--
I
F
A
M
P
G
V
--------------
N
G
T
D
Y
A
M
R
I
F
-----
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
A
E
L
E
N
L
Q
G
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
D
----
D
----
G
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
TK
L
-
S
G
-
N
K
G
E
A
V
V
E
A
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
KKGG
P
N
L
--
K
V
D
D
L
NL
P
E
I
G
P
K
F
E
H
H
E
-
M
--
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
A
C
-
A
L
V
V
A
A
V
L
-
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
-
E
-
D
-
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
---------
32
PsiBlast_CBE
62.18
42%
-10
- C4 -
-
3EJX
1
DAPF_ARATH
C:
[26-307]
-
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
A
--
D
G
V
--
I
F
A
M
P
G
V
--------------
N
G
T
D
Y
A
M
R
I
F
-----
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
A
E
L
E
N
L
Q
G
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
D
----
D
----
G
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
TK
L
-
S
G
-
N
K
G
E
A
V
V
E
A
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
KKGG
P
N
L
--
K
V
D
D
L
NL
P
E
I
G
P
K
F
E
H
H
E
-
M
--
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
A
C
-
A
L
V
V
A
A
V
L
-
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
-
E
-
D
-
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
---------
28
PsiBlast_CBE
62.11
42%
-12
- C4 -
-
3EKM
1
DAPF_ARATH
B:
[26-307]
-
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
A
--
D
G
V
--
I
F
A
M
P
G
V
--------------
N
G
T
D
Y
A
M
R
I
F
-----
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
A
E
L
E
N
L
Q
G
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
D
----
D
----
G
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
TK
L
-
S
G
-
N
K
G
E
A
V
V
E
A
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
KKGG
P
N
L
--
K
V
D
D
L
NL
P
E
I
G
P
K
F
E
H
H
E
-
M
--
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
A
C
-
A
L
V
V
A
A
V
L
-
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
-
E
-
D
-
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
---------
24
PsiBlast_CBE
62.10
42%
-14
- C4 -
-
3EKM
1
DAPF_ARATH
F:
[26-307]
-
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
A
--
D
G
V
--
I
F
A
M
P
G
V
--------------
N
G
T
D
Y
A
M
R
I
F
-----
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
A
E
L
E
N
L
Q
G
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
D
----
D
----
G
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
TK
L
-
S
G
-
N
K
G
E
A
V
V
E
A
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
KKGG
P
N
L
--
K
V
D
D
L
NL
P
E
I
G
P
K
F
E
H
H
E
-
M
--
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
A
C
-
A
L
V
V
A
A
V
L
-
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
-
E
-
D
-
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
---------
13
PsiBlast_PDB
57.01
30%
-29
- C4 -
-
5M47
1
DAPF_CORGL
A:
[3-277]
L
T
I
P
F
A
K
G
H
A
T
E
N
D
F
I
I
I
P
-
D
E
D
A
R
L
D
L
T
P
E
M
V
V
T
L
C
D
R
R
A
G
I
G
A
--
D
G
I
L
R
V
V
K
A
A
D
V
--------------
E
G
S
T
V
D
P
S
L
W
FMDYR
N
A
D
G
S
L
A
E
M
C
G
N
G
V
R
L
F
A
H
W
L
Y
S
-
R
G
L
V
D
N
T
S
F
D
I
G
T
R
A
G
V
R
H
V
D
I
L
Q
ADQH
S
----
A
Q
V
R
V
D
M
G
I
P
D
V
----------------
T
G
L
S
T
C
D
I
-
N
G
Q
-
V
F
A
G
L
G
V
D
M
G
N
P
H
L
A
C
V
V
----
P
G
L
--
S
A
S
A
L
--
A
D
M
E
L
R
A
P
T
F
D
-
Q
EF
F
P
H
G
V
N
V
E
I
V
T
E
L
E
D
D
A
V
S
M
R
V
W
E
R
G
V
G
E
T
R
S
C
G
T
G
T
V
A
A
A
C
A
A
L
A
D
-
A
G
L
G
E
G
T
V
K
V
C
V
P
G
G
E
V
E
V
Q
I
-
F
-
D
---
D
G
S
T
L
T
G
P
S
A
I
I
A
L
G
E
V
Q
I
-----
48
HHSearch
53.96
30%
-14
- C4 -
-
3FVE
3
DAPF_MYCTU
A:
[2-284]
--
M
I
F
A
K
G
H
G
T
Q
N
D
F
V
L
L
P
-
D
V
D
A
E
L
V
L
T
A
A
R
V
A
A
L
C
D
R
R
K
G
L
G
A
--
D
G
V
L
-
R
V
T
T
A
G
A
A
Q
A
V
GVLDSLPEGV
R
V
T
D
W
Y
M
D
Y
R
-----
N
A
D
G
S
A
A
Q
M
C
G
N
G
V
R
V
F
A
H
Y
L
R
A
-
S
G
L
E
V
R
D
E
F
V
V
G
S
L
A
G
P
R
P
V
T
C
H
H
----
V
EAA
Y
A
D
V
S
V
D
M
G
K
A
N
R
L
G
A
-
G
------
E
-------
A
V
---------
F
H
G
L
A
V
D
V
G
N
P
H
L
A
C
V
D
----
S
Q
L
TV
D
G
L
A
A
--
L
D
V
G
--
V
S
F
D
G
A
Q
--
F
P
D
G
V
N
V
E
V
L
T
A
P
V
D
G
A
V
W
M
R
V
H
E
R
G
V
G
E
T
R
S
C
G
T
G
T
V
-
A
A
A
V
A
A
L
A
A
V
G
S
P
T
G
T
L
T
V
H
V
P
G
G
E
V
V
V
T
V
-
T
-
D
-
A
--
T
S
F
L
R
G
P
S
V
L
V
A
R
G
D
L
A
D
D
----