@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0585: (2017-12-25 )
MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAFSEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDTGTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMFDVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNLHIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFDLAI
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20...--.....-30........40........50........60........70........80........90....-....100---------.-------------------------------------------------.......--------.110-----.....----------------.----------------...120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MT
K
A
D
T
I
F
K
E
N
I
E
R
I
L
K
EGVFSEQ--ARPKY-KDGTVANS
K
Y
V
T
GAFSEYDLSKGEFP
I
T
TL
R
P
I
A
I
K
S
A
I
K
E
V
L
W
IYQDQSN
S
L
E
V
LNDKY
N
V
H
Y
W
N-DWEVG-----------D-------------------------------------------------TGT
I
G
E
R
--------
Y
G
-------
A
V
V
K
K
----------------
H
----------------
D
I
I
N
K
L
L
K
Q
LETNPWNRR
N
I
I
S
LWD
Y
Q
A
F
E
ETDGL
L
P
C
A
F
Q
T
M
F
D
V
R
RVD
G
E
I
Y
L
D
A
T
LTQRSN
D
M
L
V
A
H
HI
N
A
M
Q
Y
V
A
L
Q
M
M
I
A
K
HFGW
K
V
G
K
F
F
Y
F
I
N
N
L
H
IYD
N
Q
F
E
Q
A
Q
E
L
L
RREPSNCQ
P
R
L
V
L
NVPDGT
N
F
F
D
I
KAE
D
F
E
L
VDYDPVK
P
Q
L
K
F
DLAI
128
Fugue
83.21
29%
0
- C- -
-
1QZF
5
?
A:
[3-521]
E
K
N
V
S
I
V
V
A
A
S
VLSSGIGINGQLPWSI
S
E
D
L
K
F
F
S
K
I
T
N
NKCDSN
K
K
N
A
L
I
M
G
R
K
T
W
D
S
I
GRRPLKN
R
I
I
V
V
I
S
SSLPQDEADPN
V
V
V
F
RNLEDSIENLMNDDSIENIFVCGG
E
S
I
Y
R
D
A
L
K
D
NFVDRIY
L
T
R
V
ALEDIEFD
T
Y
F
P
EIPETFLPV
Y
M
S
Q
T
FCTKN
I
S
Y
D
F
M
I
F
E
KQEKKTLQNCDPARGQL
K
S
I
D
D
T
V
D
L
L
G
E
I
F
GIRK
M
G
N
R
H
KFPKEEIYNTPSIRFG
R
E
H
Y
E
F
Q
Y
L
D
L
L
S
R
V
L
E
N
G
A
Y
R
E
----------
N
R
T
G
I
S
T
Y
S
I
F
G
Q
M
M
R
F
D
M
R
E
S
-
F
P
L
L
T
T
K
K
V
A
I
R
S
I
F
E
E
L
I
W
F
I
K
G
D
T
N
G
N
H
L
I
E
K
K
V
Y
I
W
S
G
N
G
S
K
E
Y
L
-----------
E
-------------------------------------------------
R
I
G
L
G
H
R
EENDLGPI
Y
G
-------
F
Q
W
R
H
----------------
Y
NGEYKTMHDDYTGVGV
D
Q
L
A
K
L
I
E
T
L
K
N
N
P
K
D
R
R
H
I
L
T
A
W
N
P
S
A
L
S
Q
M
-
A
L
P
P
C
H
V
L
S
Q
Y
Y
V
---
T
N
D
N
C
L
S
C
N
L
Y
Q
R
S
C
D
L
G
L
G
S
P
F
N
I
A
S
Y
A
I
L
T
M
M
L
A
Q
V
C
G
Y
E
P
G
E
L
A
I
F
I
G
D
A
H
I
Y
E
N
H
L
T
Q
L
K
E
Q
L
S
R
T
P
R
P
F
-
P
Q
L
K
F
K
-
R
K
V
E
N
I
E
D
F
K
W
E
D
I
E
L
I
G
Y
Y
P
-
Y
P
T
I
K
M
D
M
A
V
113
HHSearch
81.89
33%
-19
- C7 -
-
3UWL
5
TYSY_ENTFA
B:
[2-315]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
A
Y
L
A
L
G
K
K
I
L
E
E
G
H
F
K
E
D
--
R
T
------
G
T
--
G
T
Y
S
L
F
G
Y
Q
M
R
F
D
L
A
K
G
-
F
P
L
L
T
T
K
R
V
P
F
G
L
I
K
S
E
L
L
W
F
L
K
G
D
T
-
N
I
R
Y
L
L
-
E
R
N
N
H
I
W
D
-
E
W
A
F
E
-----------
R
Y
V
K
SADYQGPDMTD
F
G
H
R
V
L
Q
D
P
A
F
A
E
Q
Y
K
E
E
H
Q
K
F
C
D
A
I
L
ND
A
E
F
A
E
K
Y
G
E
L
G
N
I
--------
Y
G
-------
A
Q
W
R
H
WETKDGSF--------
I
----------------
D
Q
L
A
N
V
I
E
M
I
K
T
N
P
D
S
R
R
L
I
V
S
A
W
N
P
E
-
D
V
P
S
M
A
L
P
P
C
H
T
M
F
Q
F
Y
V
N
--
E
--
G
K
L
S
C
Q
L
Y
Q
R
S
A
D
V
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
L
I
A
H
E
T
G
L
E
V
G
E
F
V
H
T
L
G
D
A
H
L
Y
Q
N
H
V
E
Q
M
Q
E
Q
L
S
R
E
V
R
S
F
-
P
T
L
V
L
N
P
-
D
K
A
S
V
F
D
F
D
M
E
D
I
K
V
E
G
Y
D
P
-
H
P
T
I
K
A
P
I
A
V
5
PsiBlast_PDB
81.64
33%
1
- C7 -
-
1BSP
-
TYSY1_BACSU
A:
[1-278]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
F
D
K
Q
Y
N
S
I
I
K
D
I
I
N
N
G
I
S
D
-
E
FD
V
R
T
K
W
D
S
D
G
T
P
A
H
T
L
S
V
I
S
K
Q
M
R
F
D
N
S
--
E
V
P
I
L
T
T
K
K
V
A
W
K
T
A
I
K
E
L
L
W
I
W
Q
L
K
S
N
D
V
N
D
L
N
-
M
M
G
V
H
I
W
D
-
Q
W
K
Q
E
-----------
D
--------------------------------------------------
G
T
I
G
H
A
--------
Y
G
-------
F
Q
L
G
K
----------------
K
NRSLNG
E
K
V
-------
D
Q
V
D
Y
L
L
H
Q
L
K
N
N
P
S
S
R
R
H
I
T
M
L
W
N
P
D
E
L
D
A
M
-
A
L
T
P
C
V
Y
E
T
Q
W
Y
V
K
H
--
G
K
L
H
L
E
--
V
R
A
R
S
N
D
M
A
L
G
N
P
F
N
V
F
Q
Y
N
V
L
Q
R
M
I
A
Q
V
T
G
Y
E
L
G
E
Y
I
F
N
I
G
D
C
H
V
Y
T
R
H
I
D
N
L
K
I
Q
M
E
R
E
Q
F
E
A
-
P
E
L
W
I
N
-
P
E
V
K
D
F
Y
D
F
T
I
D
D
F
K
L
I
N
Y
K
H
-
G
D
K
L
L
F
E
V
A
V
34
PsiBlast_CBE
80.91
33%
-30
- C7 -
-
4FOX
3
TYSY_MYCTU
C:
[13-261]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
R
T
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
VQWRSWP
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
V
--
37
PsiBlast_CBE
80.80
33%
-26
- C7 -
-
4FOG
3
TYSY_MYCTU
C:
[13-262]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
R
T
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
VQWRSWP
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
V
A
-
28
PsiBlast_CBE
80.58
33%
-26
- C7 -
-
4FQS
3
TYSY_MYCTU
B:
[13-263]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
R
T
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
VQWRSWP
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
V
A
V
115
HHSearch
80.43
33%
-47
- C7 -
-
4FOX
3
TYSY_MYCTU
D:
[1-263]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
P
Y
E
D
L
L
R
F
V
L
E
T
G
T
P
K
S
D
--
R
T
------
G
T
--
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
-
N
I
G
W
L
H
-
E
H
G
V
T
I
W
D
-
E
W
A
S
D
-------------------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
-------
V
Q
W
R
S
WPAPSGEH--------
I
----------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
-
E
I
E
R
M
A
L
P
P
C
H
A
F
F
Q
F
Y
V
A
--
D
--
G
R
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
R
P
Y
-
P
K
L
L
L
A
D
--
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
V
A
V
12
PsiBlast_PDB
80.35
33%
-25
- C7 -
-
4FQS
3
TYSY_MYCTU
A:
[13-263]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
R
T
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
V
Q
W
R
SWP
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
V
A
V
33
PsiBlast_CBE
80.27
33%
-33
- C7 -
-
4FOX
3
TYSY_MYCTU
D:
[13-263]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
R
T
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
VQWRSWP
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
V
A
V
4
PsiBlast_PDB
80.18
33%
5
- C7 -
-
1BSF
-
TYSY1_BACSU
A:
[2-279]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
F
D
K
Q
Y
N
S
I
I
K
D
I
I
N
N
G
I
S
D
E
E
FD
V
R
T
K
W
D
S
D
G
T
P
A
H
T
L
S
V
I
S
K
Q
M
R
F
D
N
S
--
E
V
P
I
L
T
T
K
K
V
A
W
K
T
A
I
K
E
L
L
W
I
W
Q
L
K
S
N
D
V
N
D
L
N
-
M
M
G
V
H
I
W
D
-
Q
W
K
Q
E
-----------
D
--------------------------------------------------
G
T
I
G
H
A
--------
Y
G
-------
F
Q
L
G
K
----------------
K
NRSLNG
E
K
V
-------
D
Q
V
D
Y
L
L
H
Q
L
K
N
N
P
S
S
R
R
H
I
T
M
L
W
N
P
D
E
L
D
A
M
-
A
L
T
P
C
V
Y
E
T
Q
W
Y
V
K
H
--
G
K
L
H
L
E
--
V
R
A
R
S
N
D
M
A
L
G
N
P
F
N
V
F
Q
Y
N
V
L
Q
R
M
I
A
Q
V
T
G
Y
E
L
G
E
Y
I
F
N
I
G
D
C
H
V
Y
T
R
H
I
D
N
L
K
I
Q
M
E
R
E
Q
F
E
A
-
P
E
L
W
I
N
-
P
E
V
K
D
F
Y
D
F
T
I
D
D
F
K
L
I
N
Y
K
H
-
G
D
K
L
L
F
E
V
A
V
116
HHSearch
79.83
33%
-39
- C7 -
-
4FQS
3
TYSY_MYCTU
A:
[1-263]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
P
Y
E
D
L
L
R
F
V
L
E
T
G
T
P
K
S
D
--
R
T
------
G
T
--
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
-
N
I
G
W
L
H
-
E
H
G
V
T
I
W
D
-
E
W
A
S
D
-------------------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
-------
V
Q
W
R
S
WPAPSGEH--------
I
----------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
-
E
I
E
R
M
A
L
P
P
C
H
A
F
F
Q
F
Y
V
A
--
D
--
G
R
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
R
P
Y
-
P
K
L
L
L
A
D
--
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
V
A
V
30
PsiBlast_CBE
79.78
33%
-22
- C7 -
-
4FOX
3
TYSY_MYCTU
G:
[13-260]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
R
T
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
VQWRSWP
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
---
1
PsiBlast_PDB
79.77
33%
7
- C7 -
-
1B02
2
TYSY1_BACSU
A:
[1-279]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
Q
F
D
K
Q
Y
N
S
I
I
K
D
I
I
N
N
G
I
S
D
E
E
FD
V
R
T
K
W
D
S
D
G
T
P
A
H
T
L
S
V
I
S
K
Q
M
R
F
D
N
S
--
E
V
P
I
L
T
T
K
K
V
A
W
K
T
A
I
K
E
L
L
W
I
W
Q
L
K
S
N
D
V
N
D
L
N
-
M
M
G
V
H
I
W
D
-
Q
W
K
Q
E
-----------
D
--------------------------------------------------
G
T
I
G
H
A
--------
Y
G
-------
F
Q
L
G
K
----------------
K
NRSLNG
E
K
V
-------
D
Q
V
D
Y
L
L
H
Q
L
K
N
N
P
S
S
R
R
H
I
T
M
L
W
N
P
D
E
L
D
A
M
-
A
L
T
P
C
V
Y
E
T
Q
W
Y
V
K
H
--
G
K
L
H
L
E
--
V
R
A
R
S
N
D
M
A
L
G
N
P
F
N
V
F
Q
Y
N
V
L
Q
R
M
I
A
Q
V
T
G
Y
E
L
G
E
Y
I
F
N
I
G
D
C
H
V
Y
T
R
H
I
D
N
L
K
I
Q
M
E
R
E
Q
F
E
A
-
P
E
L
W
I
N
-
P
E
V
K
D
F
Y
D
F
T
I
D
D
F
K
L
I
N
Y
K
H
-
G
D
K
L
L
F
E
V
A
V
2
PsiBlast_PDB
79.72
33%
3
- C7 -
-
1BKO
-
TYSY1_BACSU
A:
[2-279]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
F
D
K
Q
Y
N
S
I
I
K
D
I
I
N
N
G
I
S
D
E
E
FD
V
R
T
K
W
D
S
D
G
T
P
A
H
T
L
S
V
I
S
K
Q
M
R
F
D
N
S
--
E
V
P
I
L
T
T
K
K
V
A
W
K
T
A
I
K
E
L
L
W
I
W
Q
L
K
S
N
D
V
N
D
L
N
-
M
M
G
V
H
I
W
D
-
Q
W
K
Q
E
-----------
D
--------------------------------------------------
G
T
I
G
H
A
--------
Y
G
-------
F
Q
L
G
K
----------------
K
NRSLNG
E
K
V
-------
D
Q
V
D
Y
L
L
H
Q
L
K
N
N
P
S
S
R
R
H
I
T
M
L
W
N
P
D
E
L
D
A
M
-
A
L
T
P
C
V
Y
E
T
Q
W
Y
V
K
H
--
G
K
L
H
L
E
--
V
R
A
R
S
N
D
M
A
L
G
N
P
F
N
V
F
Q
Y
N
V
L
Q
R
M
I
A
Q
V
T
G
Y
E
L
G
E
Y
I
F
N
I
G
D
C
H
V
Y
T
R
H
I
D
N
L
K
I
Q
M
E
R
E
Q
F
E
A
-
P
E
L
W
I
N
-
P
E
V
K
D
F
Y
D
F
T
I
D
D
F
K
L
I
N
Y
K
H
-
G
D
K
L
L
F
E
V
A
V
121
HHSearch
79.63
30%
0
- C7 -
-
1HVY
4
TYSY_HUMAN
C:
[1-288]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
P
H
G
E
L
Q
Y
L
G
Q
I
Q
H
I
L
R
C
G
V
R
K
D
D
--
R
T
------
G
T
--
G
T
L
S
V
F
G
M
Q
A
R
Y
S
L
R
D
-
E
F
P
L
L
T
T
K
R
V
F
W
K
G
V
L
E
E
L
L
W
F
I
K
G
S
T
-
N
A
K
E
L
S
-
S
K
G
V
K
I
W
D
-
A
N
G
S
R
DFLDSLGFSTR
E
-------------------------------------------------
E
G
D
L
G
P
V
--------
Y
G
-------
F
Q
W
R
H
FGAEYRDMESDYSGQG
V
----------------
D
Q
L
Q
R
V
I
D
T
I
K
T
N
P
D
D
R
R
I
I
M
C
A
W
N
P
R
-
D
L
P
L
M
A
L
P
P
C
H
A
L
C
Q
F
Y
V
V
--
N
--
S
E
L
S
C
Q
L
Y
Q
R
S
G
D
M
G
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
Y
M
I
A
H
I
T
G
L
K
P
G
D
F
I
H
T
L
G
D
A
H
I
Y
L
N
H
I
E
P
L
K
I
Q
L
Q
R
E
P
R
P
F
-
P
K
L
R
I
L
R
-
K
V
E
K
I
D
D
F
K
A
E
D
F
Q
I
E
G
Y
N
P
-
H
P
T
I
K
M
E
M
A
V
11
PsiBlast_PDB
79.50
33%
-31
- C7 -
-
4FOX
3
TYSY_MYCTU
A:
[13-261]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
R
T
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
V
Q
W
R
SWP
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
V
--
32
PsiBlast_CBE
79.29
33%
-25
- C7 -
-
4FOX
3
TYSY_MYCTU
E:
[13-260]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
R
T
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
VQWRSWP
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
---
26
PsiBlast_CBE
79.13
33%
-25
- C7 -
-
3QJ7
2
TYSY_MYCTU
C:
[14-262]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
--
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
V
Q
W
R
SWP
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
V
--
10
PsiBlast_PDB
79.03
33%
-21
- C7 -
-
4FOG
3
TYSY_MYCTU
A:
[13-260]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
R
T
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
V
Q
W
R
SWP
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
---
23
PsiBlast_CBE
78.72
33%
-20
- C7 -
-
4FOA
2
TYSY_MYCTU
C:
[14-261]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
--
G
T
P
K
--
S
D
R
T
G
T
G
T
R
S
L
F
G
Q
Q
M
R
Y
D
L
S
A
G
-
F
P
L
L
T
T
K
K
V
H
F
K
S
V
A
Y
E
L
L
W
F
L
R
G
D
S
N
-
I
G
W
L
H
E
-
H
G
V
T
I
W
D
-
E
W
-
A
S
-----------
D
-------------------------------------------------
T
G
E
L
G
P
I
--------
Y
G
V
Q
W
R
S
W
P
A
P
S
G
E
----------------
H
I---------------
D
Q
I
S
A
A
L
D
L
L
R
T
D
P
D
S
R
R
I
I
V
S
A
W
N
V
G
E
I
E
R
M
-
A
L
P
P
C
--
H
A
F
F
Q
F
Y
V
A
D
G
R
--
L
S
C
Q
L
Y
Q
R
S
A
D
L
F
L
G
V
P
F
N
I
A
S
Y
A
L
L
T
H
M
M
A
A
Q
A
G
L
S
V
G
E
F
I
W
T
G
G
D
C
H
I
Y
D
N
H
V
E
Q
V
R
L
Q
L
S
R
E
P
-
R
P
Y
P
K
L
L
L
A
--
D
R
D
S
I
F
E
Y
T
Y
E
D
I
V
V
K
N
Y
D
P
-
H
P
A
I
K
A
P
---