@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKC4: (2017-10-26 )
MKFLPVILSLALITNASYANPFDPKPASGQVEIPNIGSGIGLLDQQKEKFIGEKVFREVHKQMPVIQDVWLEDQFFQVFSNILSETQLGQPIALVVIKDPQINAFAVPGGLFALNTGLISSARNIDEIAGVMAHEIAHVSQRHFSRSEEAFKGQTLLSLAGLLAGVALAAQAGGDAGAAVMLGTQAALLDKQLTYSRNQEREADRIGMQYMYAAGYNPQSMADYFETMHRATSRVSFLPDFWLTHPLTSERMSEARLRANQMPKVKSRIYDVDFEILKWYTMVVAGEATENQLQSLASQKNLAGLLALSAFYLKQGDYTQAQATLEQAKSSGKPLVALIQTDIYLGQNKINQAYNSIAPLQMTMPENKAFSYKLAEVLLRQGKYAQVQTLVQRFINKNARDIQGWQLLQQAANLDKNSPLRAVNVLRYRAEAQYWSGSEEDAIKSMLHAQRLAKGNQAMSARIDSRLKQMQDERRMKI
Atome Classification :
(20 SA)
---------------------------------------....-.----....10---........20.-.......30--.------.......40........50.-----......-------.60........70-........-80...--------.....-----------------------------90.........----100......----.---110.....----..120.------------------..--------....---------130......---.140.......150----------.......160-....------...-----.-----170..----------.------..--.----.180---.------...-.-....190.-----......200..-----....--------------------.210.......220.......230.---.----.----....----240......----------------.250.......260-------.......270.......280.......290.....-------------------------------..300..----.....310...-....320---...---------....--.330-......---.340-----..-.....350...-----------....360......---.370......---------..380----------.--.-......390-...----------....400....-...410.......420-------....----------.....------------------430.......440.......450....------..---.460.-......470.--.....------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------MK
F
L
-
P
----
V
I
L
S
L
A
---
L
ITNASYANPF-DPKPASG
Q
V
--E------IPNIGSGIG
L
L
D
Q
Q
K
E
K
F
I
G
-----
E
K
V
F
R
E
-------
V
H
K
QMP
V
I
Q
D
VWL-
E
D
Q
F
F
Q
V
F
-
S
N
I
L
S
--------
E
T
QLG-----------------------------Q-
P
I
A
L
V
V
I
KD----PQI
N
A
F
AVP----G---
G
L
F
A
L
N
T
G
----
L
I
SSAR------------------
N
I
--------
D
E
I
A
---------
G
V
M
A
H
E
I
A
H
---
V
S
Q
R
HFSR
S
E
E
AFK----------G
Q
T
L
L
S
L
A
G
--
L
L
A
G
------
V
A
L
-----
A
-----AQAGG----------D------A
G
--
A
----
A
V
-----
M
------LG
T
-
Q
-
A
A
L
L
D
K
Q
L-----TYSRNQE
R
E
A
D
-----
R
I
G
M
--------------------
Q
Y
MYAAGY
N
P
Q
S
M
A
D
Y
F
E
T
M
H
R
A
T
S
---R----V----SFL
P
----
D
F
WLTHP
L
T
----------------
S
E
R
M
S
E
A
R
L
RANQM-------
P
K
V
K
S
R
IYDV
D
F
E
I
L
K
W
Y
T
M
V
V
AGE
A
T
E
N
Q
L
Q
S
L
A
-------------------------------SQ
K
N
L
A
G
----
L
L
A
L
S
A
F
Y
LKQ-GD
Y
T
Q
A
----
Q
A
T
---------
L
E
Q
A
--KSSG-
K
P
L
V
A
L
---
I
Q
T
D
-----
I
Y-LG
Q
N
K
I
N
Q
A
Y
N-----------SIA
P
L
Q
M
TMPENK---A
F
-
S
Y
K
L
A
E
V
---------
L
L
RQ-----------G--
K
-
Y
A
Q
V
Q
T
L
V
Q
-
R
F
I
----------NKNARD
I
Q
G
W
Q
-
L
L
Q
Q
A
ANLDKNSP
L
---------
R
A
V
N
----------
V
L
R
Y
R------------------AEAQYWSGS
E
E
D
A
I
K
S
M
L
H
A
Q
R
L
AKGN------
Q
A
---
M
S
A
R
I
-
D
S
R
L
K
Q
M
Q
D
E
--RRMKI------------------------------------------------------------------------------------------
1
PsiBlast_PDB
65.03
30%
-21
- C6 -
-
3C37
1
?
A:
[10-241]
----------------------------------------------------------------------------------------------
G
F
N
M
I
S
I
E
Q
E
K
E
L
G
-----
N
K
F
A
V
E
-------
I
E
K
Q
Q
Q
P
V
N
D
P
E
V
-
Q
R
Y
V
D
K
V
G
-
K
R
L
L
S
--------
G
A
R
A
V
-----------------------------
E
F
D
Y
V
F
K
V
V
K
D
----
D
S
V
N
A
F
A
I
P
----
G
---
G
R
V
Y
V
H
T
G
----
L
L
K
A
A
D
------------------
N
E
--------
T
E
L
A
---------
G
V
L
A
H
E
I
N
H
---
A
V
A
R
H
G
T
R
Q
M
T
Q
E
Y
----------
G
Y
S
L
V
-
L
S
L
--
V
L
G
D
N
M
L
---
A
Q
L
-----
A
-----
G
Q
L
F
G
----------
K
------
A
G
--
M
----
M
--------------------------------
S
Y
S
R
E
Y
E
N
Q
A
D
-----
F
L
G
V
--------------------
E
T
M
Y
K
A
G
Y
N
P
N
G
L
T
S
F
F
Q
K
L
N
A
----------------------------
T
H
P
L
T
----------------
S
E
R
I
Q
R
V
Q
A
E
I
A
K
L
-------
P
P
Q
R
Y
L
T
D
E
T
E
F
K
K
I
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
58.39
21%
7
- C4 -
-
5T6O
-
PHAC_CUPNH
A:
[1-389]
---------------------------------------
S
A
F
E
-
V
GRNV
A
V
T
E
G
A
---
V
V
F
E
N
E
Y
F
Q
L
L
-
Q
Y
K
P
L
T
D
K
V
--
H
A
R
P
L
L
M
V
P
P
C
I
N
K
Y
Y
I
L
D
L
Q
P
E
S
S
L
V
-----
R
H
V
V
E
Q
-----------------------------------------------
G
-----------------------------
H
-
T
V
F
L
V
S
W
R
N
----
P
D
A
S
M
A
G
------------------------
S
T
W
D
------------------
D
Y
--------
I
E
H
A
---------
A
I
R
A
I
E
V
A
R
---
D
I
S
G
Q
D
K
I
N
V
L
G
F
----------------
A
V
G
G
--
T
I
V
S
------
T
A
L
-----
A
-----
V
L
A
A
R
----------
G
------
E
H
--
P
----
A
A
-----
S
------
V
T
L
-
L
-
T
T
L
L
D
F
A
D
-----
T
G
I
L
D
V
F
V
D
E
G
-----
H
V
Q
G
--------------------
A
--------
P
C
A
L
L
R
G
L
E
L
A
N
T
F
S
-----------------------
F
L
R
P
N
D
L
V
----------------
W
N
Y
V
V
D
N
Y
L
K
G
N
----------------
T
P
V
P
F
D
L
L
F
W
N
G
-----------------------------------------------
D
A
T
N
L
P
G
----
P
W
Y
C
--
W
Y
L
R
H
-
T
Y
L
Q
N
E
----
L
K
V
---------
P
G
K
L
--
T
V
C
G
-
V
P
V
D
L
A
SID
V
P
T
Y
-----
I
Y
-
G
S
R
E
------
D
-----------
H
I
V
P
W
T
A
A
Y
A
S
T
A
---
L
L
-
A
N
K
L
R
F
V
---------
L
G
A
S
-----------
G
--
H
-
I
A
G
V
--------
I
----------
N
P
P
A
K
N
-----------
K
R
S
H
W
T
N
D
A
---------
L
P
E
S
----------
P
Q
Q
W
L
------------------
A
G
A
I
E
H
H
G
S
W
W
P
D
W
T
A
W
L
A
G
Q
--
A
G
A
K
------
R
A
---
A
P
A
N
Y
G
N
A
R
Y
R
A
I
E
P
A
PG
R
Y
V
K
A
KA----------------------------------------------------------------------------------------
19
Fugue
52.60
13%
43
- C5 -
-
5CTQ
-
SART3_HUMAN
A:
[44-561]
-------------------------------------------------
N
Q
L
E
I
E
---
R
L
E
E
Q
L
S
I
N
V
Y
-
D
Y
N
C
H
V
D
L
I
--
R
------
L
L
R
L
E
G
E
L
T
K
V
R
M
A
R
Q
K
M
S
E
I
FPLT
E
E
L
W
L
E
W
------
L
H
D
E
I
S
M
A
Q
D
G
L
D
-
R
E
H
V
Y
D
L
F
-
E
K
A
V
K
--------
D
Y
I
C
--------------------------------
P
N
I
W
L
E
Y
G
Q
----
Y
S
V
G
G
I
G
Q
K
----
G
---
G
L
E
K
V
R
S
V
----
F
E
R
A
L
S
------------------
S
V
GLHMTK
G
L
A
L
W
E
---------
A
Y
R
E
F
E
S
A
I
---
V
E
A
A
R
L
E
K
V
H
S
L
F
R
----------
R
Q
L
A
I
P
L
Y
D
--
M
E
A
T
------
F
A
E
-----
Y
-----
E
E
W
S
E
----------
D
------
P
I
--
P
----
E
S
-----
V
------
I
Q
N
-
Y
-
N
K
A
L
Q
Q
L
E
-----
K
Y
K
P
Y
E
E
A
L
L
Q
AEAPR
L
A
E
Y
--------------------
Q
A
Y
I
D
F
E
M
K
I
G
D
P
A
R
I
Q
L
I
F
E
R
A
L
V
---
E
----
N
----
C
L
V
P
----
D
L
W
I
R
Y
S
Q
Y
----------------
L
D
R
Q
L
K
V
K
D
L
V
L
S
V
-------
H
N
R
A
I
R
N
C
P
W
T
V
A
L
W
S
R
Y
L
L
A
M
E
R
H
G
V
D
H
Q
V
I
S
V
T
-------------------------------
F
E
K
A
L
N
A
GFIQ
A
T
D
Y
V
E
I
W
Q
A
Y
-
L
D
Y
L
R
R
----
R
V
D
---------
F
K
Q
D
--
S
S
K
E
L
E
E
L
R
A
A
---
F
T
R
A
-----
L
E
-
Y
L
K
Q
E
V
E
E
R
F
N
ESGDPSC
V
I
M
Q
N
W
A
R
I
E
A
R
L
C
N
N
M
---
Q
K
-
A
R
E
L
W
D
S
---------
I
M
T
R
-----------
G
NA
K
-
Y
A
N
M
W
L
E
Y
Y
-
N
L
E
----------
R
A
H
G
D
T
Q
H
C
R
K
-
A
L
H
R
A
V
Q
C
T
S
D
Y
P
E
---------
H
V
C
E
----------
V
L
L
T
M
------------------
E
R
T
E
G
S
L
E
D
W
D
I
A
V
Q
K
T
E
T
R
L
A
R
V
N
E
Q
------
R
M
---
K
A
A
E
K
-
E
A
A
L
V
Q
Q
E
E
E
--
K
A
E
Q
R
K
R
A
RAEKKAL--------------------------------------------------------------------------------
14
Fugue
51.40
13%
-55
- C5 -
-
4AIF
-
AIP_HUMAN
A:
[1-144]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
E
-------------------------------
K
A
K
A
V
P
L
----
I
H
Q
E
G
N
R
L
Y
R
E
-
G
H
V
K
E
A
----
A
A
K
---------
Y
Y
D
A
--
I
A
C
L
-
K
N
L
Q
M
-----------------------
K
E
Q
P
-----------
G
S
P
E
W
I
Q
L
D
Q
Q
I
T
---
P
L
-
L
L
N
Y
C
Q
C
---------
K
L
V
V
-----------
E
--
E
-
Y
Y
E
V
L
D
H
C
S
-
S
I
L
----------
N
K
Y
D
D
N
-------------------------------
V
K
----------
A
Y
F
K
R
------------------
G
K
A
H
A
A
V
W
N
A
Q
E
A
Q
A
D
F
A
K
V
L
E
L
---
D
------
P
A
---
L
A
P
V
V
-
S
R
E
L
Q
A
L
E
A
R
--
I
R
Q
--------------------------------------------------------------------------------------------
20
Fugue
50.51
17%
36
- C1 -
-
5I4A
1
?
A:
[4-642]
-----------------------AYLN
L
Y
K
I
D
I
PK
K
I
K
R
L
Y
F
Y
N
P
----
D
M
E
P
K
L
---
F
A
R
N
L
S
R
V
N
N
F
-
K
F
Q
D
S
N
D
L
V
W
I
E
------
I
P
D
I
D
F
Q
I
T
P
K
N
V
F
Q
Y
K
V
E
K
-----
E
E
I
I
K
E
EED
K
K
L
F
V
K
T
L
Y
K
Y
I
K
K
L
F
L
-
D
N
D
F
Y
F
K
K
G
N
N
F
I
S
--------
N
S
E
V
F
SLDSNEN
V
N
A
H
L
T
Y
K
I
K
I
H
N
I
SN
E
Y
Y
L
S
I
L
-
P
K
F
T
F
L
S
K
E
----
P
A
L
E
S
A
I
K
S
----
G
---
Y
L
Y
N
I
K
S
G
K
S
F
P
Y
I
S
G
L
D
------------------
G
I
--------
L
K
I
D
---------
I
N
Q
I
V
E
V
A
Y
---
P
E
N
Y
L
F
N
F
T
T
R
D
A
E
K
Y
GF------
S
K
E
V
H
E
I
Y
K
N
K
V
F
E
G
------
F
K
K
-----
I
-----
P
K
T
L
G
----------
F
------
L
N
--
K
----
I
T
-----
N
------
L
N
E
-
N
-
Y
Q
D
G
Y
K
I
F
I
N
V
I
Y
K
F
K
N
G
E
S
R
Y
A
K
-----
D
V
F
K
YSFYKNE
Q
P
L
K
A
I
F
F
F
SS
K
K
Q
F
F
E
V
Q
K
S
L
K
E
L
F
H
N
K
H
S
V
F
Y
R
A
A
A
---
E
----
L
----
G
F
S
K
----
V
E
F
L
R
D
S
K
T
KSS
A
F
L
Y
NPEEF
T
V
K
N
T
E
F
I
N
Q
I
E
D
N
V
M
A
I
-------
V
L
L
D
K
Y
I
G
N
I
D
P
L
V
R
N
F
P
D
N
L
I
L
Q
P
I
L
K
E
K
L
E
D
I
K
-------------------------------
P
F
I
I
K
S
Y
----
V
Y
K
M
G
N
F
I
P
E
C
-
K
P
F
I
L
K
----
K
M
E
DKEK
N
L
Y
I
G
I
D
L
S
--
H
D
A
R
-
K
T
N
L
C
I
---
A
A
V
D
NTGDI
L
Y
-
I
G
K
H
K
-
N
L
E
L
N
-----------
E
K
M
N
L
D
I
L
E
K
E
Y
I
---
K
A
-
F
E
K
Y
I
E
K
FNVSPE
N
V
F
I
L
R
D
-----------
G
--
R
-
F
I
E
D
I
E
I
I
K
-
N
F
I
SD
T
K
Y
T
L
V
E
V
N
K
N
T
-
N
I
N
S
Y
D
D
L
K
E
W
I
I
K
L
D
E
N
T
Y
I
Y
Y
P
KTFL
N
Q
K
G
V
E
----------
V
K
I
L
E
------------------
N
N
T
D
Y
---
T
I
E
E
I
I
E
Q
I
Y
L
L
T
R
V
A
H
S
T
PYTNYK
L
P
---
Y
P
L
H
I
-
A
N
K
V
A
L
T
D
Y
E
--
W
K
L
Y
I
PY----------------------------------------------------------------------------------------
34
HHSearch
50.30
25%
-80
- C6 -
-
3CQB
2
HTPX_VIBPA
A:
[24-103]
------------------------------------------------------------------------------------------------------------------------------------------
T
-
E
H
W
L
L
E
T
V
-
G
R
Q
A
Q
--------
Q
A
G
I
G
-----------------------------
M
--
P
T
V
A
I
Y
D
S
----
A
D
I
N
A
F
A
T
G
AK--
D
---
S
L
V
A
V
S
T
G
----
L
L
H
N
M
-------------------
T
R
--------
D
E
A
E
---------
A
V
L
A
H
E
V
S
H
---
I
A
N
G
D
M
V
T
M
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
48.96
19%
-9
* C4 *
-
5I0P
-
?
A:
[13-366]
-------------------------------------------------------------
E
H
Q
L
D
Y
P
F
A
D
T
L
P
A
A
G
D
T
----------
F
E
V
A
P
G
V
R
W
L
R
M
P
------------------------
L
P
F
S
L
D
H
I
N
L
W
L
L
-
R
D
E
I
------------------
D
G
Q
A
G
-----------------------------
W
-
T
I
V
D
C
G
I
S
S
----
E
A
I
R
T
H
W
E
Q
---------
I
F
D
R
H
L
D
----
G
L
P
V
L
R
------------------
V
L
---------------------------
V
T
H
---
C
H
P
D
H
F
--------------------------------
G
------
L
A
N
-----
W
-----
L
C
E
G
G
----------
D
------
Q
G
-----------------------------------------------
R
W
N
V
-----
R
L
W
M
T
L
G
-----------------
E
Y
M
F
G
C
L
M
A
A
G
A
A
A
D
H
F
A
R
H
G
L
-----------------
Y
Y
S
----
D
L
V
P
A
V
P
P
R
----------------
Y
R
R
L
R
E
G
D
-----------------------
A
V
K
I
G
A
R
T
W
R
V
V
T
G
Y
G
H
S
P
E
H
C
A
L
H
-------------------------------
S
E
A
D
--
G
----
V
L
I
S
G
D
M
V
L
P
R
----
I
S
T
----
N
V
S
---------
V
F
D
L
--
E
P
E
A
-
N
P
L
A
L
Y
---
L
E
S
---------------
L
G
R
Y
E
-----------
T
M
A
P
D
T
L
V
L
P
---------------------------
S
H
-----------
G
--
K
P
F
R
G
V
R
T
R
I
A
-
Q
L
R
----------
A
H
H
D
A
R
L
E
E
V
R
-
V
A
C
A
E
------
K
P
M
---------
S
A
A
G
----------
I
V
P
I
M
------------------
F
T
--------
F
A
L
G
E
A
L
A
H
L
N
L
L
W
L
A
G
------
E
L
---
V
R
E
H
G
-
D
D
G
V
I
R
Y
A
R
A
-------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
48.38
25%
-22
- C5 -
-
2HYZ
-
?
A:
[11-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Y
K
Q
-
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
---------
L
E
L
D
--
P
R
S
A
-
E
A
W
Y
N
L
-----
G
N
-----
A
Y
-
Y
K
Q
G
D
Y
D
E
A
I
E
-----------
Y
Y
Q
K
A
L
E
L
D
P
R
S
A
---
E
A
-
W
Y
N
L
G
N
A
---------
Y
Y
K
Q
-----------
G
--
D
-
Y
D
E
A
I
E
Y
Y
Q
-
K
A
L
----------
E
L
D
P
R
S
A
E
A
W
Y
-
N
L
G
N
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
48.03
25%
-12
- C5 -
-
2FO7
-
?
A:
[11-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Y
K
Q
-
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
---------
L
E
L
D
--
P
R
S
A
-
E
A
W
Y
N
L
-----
G
N
-----
A
Y
-
Y
K
Q
G
D
Y
D
E
A
I
E
-----------
Y
Y
Q
K
A
L
E
L
D
P
R
S
A
---
E
A
-
W
Y
N
L
G
N
A
---------
Y
Y
K
Q
-----------
G
--
D
-
Y
D
E
A
I
E
Y
Y
Q
-
K
A
L
----------
E
L
D
P
R
S
A
E
A
W
Y
-
N
L
G
N
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
46.72
18%
19
- C5 -
-
3AS5
-
?
A:
[6-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
Q
V
Y
----
Y
R
D
K
G
I
S
H
A
K
A
-
G
R
Y
S
Q
A
----
V
M
L
---------
L
E
Q
V
YD
A
D
A
F
-
D
V
D
V
A
L
---
H
L
G
I
-----
A
Y
-
V
K
T
G
A
V
D
R
G
T
E
-----------
L
L
E
R
S
L
A
D
A
P
D
N
V
---
K
V
-
A
T
V
L
G
L
T
---------
Y
V
Q
V
-----------
Q
--
K
-
Y
D
L
A
V
P
L
L
I
-
K
V
A
----------
E
A
N
P
I
N
F
N
V
R
F
-
R
L
G
V
A
L
D
N
L
G
R
F
-------------
D
E
----------
A
I
D
S
F
K
I
A
L
G
L
RPNE
G
K
V
H
R
A
I
-
A
F
S
Y
E
Q
M
G
R
H
E
E
A
L
P
H
F
K
K
A
N
E
L
D
E
G
A
------
S
V
--------------------------------------------------------------------------------------------------------------------
28
HHSearch
45.85
18%
17
- C5 -
-
3AS5
-
?
B:
[9-177]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
----
Y
R
D
K
G
I
S
H
A
K
A
-
G
R
Y
S
Q
A
----
V
M
L
---------
L
E
Q
V
YD
A
D
A
F
-
D
V
D
V
A
L
---
H
L
G
I
-----
A
Y
-
V
K
T
G
A
V
D
R
G
T
E
-----------
L
L
E
R
S
L
A
D
A
P
D
N
V
---
K
V
-
A
T
V
L
G
L
T
---------
Y
V
Q
V
-----------
Q
--
K
-
Y
D
L
A
V
P
L
L
I
-
K
V
A
----------
E
A
N
P
I
N
F
N
V
R
F
-
R
L
G
V
A
L
D
N
L
G
R
F
-------------
D
E
----------
A
I
D
S
F
K
I
A
L
G
L
RPNE
G
K
V
H
R
A
I
-
A
F
S
Y
E
Q
M
G
R
H
E
E
A
L
P
H
F
K
K
A
N
E
L
D
E
G
A
----------------------------------------------------------------------------------------------------------------------------
38
HHSearch
45.20
13%
9
- C5 -
-
2Q7F
-
YRRB_BACSU
B:
[55-228]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
D
A
I
P
----
Y
I
N
F
A
N
L
L
S
S
V
-
N
E
L
E
R
A
----
L
A
F
---------
Y
D
K
A
LE
L
D
S
S
-
A
A
T
A
Y
Y
---
G
A
G
N
-----
V
Y
-
V
V
K
E
M
Y
K
E
A
K
D
-----------
M
F
E
K
A
L
R
A
G
M
E
N
G
---
D
L
-
F
Y
M
L
G
T
V
---------
L
V
K
L
-----------
E
--
Q
-
P
K
L
A
L
P
Y
L
Q
-
R
A
V
----------
E
L
N
E
N
D
T
E
A
R
F
-
Q
F
G
M
C
L
A
N
E
G
M
L
-------------
D
E
----------
A
L
S
Q
F
AAVTEQDPGHADAFYNA-
G
V
T
Y
A
Y
K
E
N
R
E
K
A
L
E
M
L
D
K
A
I
D
I
Q
P
D
H
------
M
---------------------------------------------------------------------------------------------------------------------
23
HHSearch
44.84
20%
-43
- C6 -
-
4IL3
-
?
B:
[230-446]
---------------------------------------------------------------------------------------------------------------------------------------------
G
E
L
K
K
S
I
-
E
S
L
A
D
--------
R
V
G
F
P
-----------------------------
L
-
D
-
K
I
F
V
I
D
G
SKRS
S
H
S
N
A
Y
F
T
G
LPF
T
S
---
K
R
I
V
L
F
D
T
----
L
V
N
S
N
-------------------
S
T
--------
D
E
I
T
---------
A
V
L
A
H
E
I
G
H
---
W
Q
K
N
H
I
V
N
M
V
I
F
S
Q
----------
L
H
T
F
L
I
F
-
S
--
L
F
-
T
------
S
I
Y
-----
R
NS
S
F
Y
N
T
F
G
F
FVEKSSSGFV
D
P
V
I
TKE
F
P
I
I
I
----
G
F
M
L
F
N
D
L
------
L
T
P
L
E
-
C
A
M
Q
F
I
M
S
-----
L
I
S
R
T
H
E
Y
Q
A
D
-----
A
Y
A
K
--------------------
K
L
----
G
Y
-
K
Q
N
L
C
R
A
L
I
D
L
Q
I
K
N
L
---
S
TMNV
D
----
P
L
Y
S
----
S
Y
H
Y
S
H
P
T
L
----------------
A
E
R
L
T
A
L
D
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
43.53
20%
-35
* C6 *
-
4IL3
-
?
A:
[230-445]
---------------------------------------------------------------------------------------------------------------------------------------------
G
E
L
K
K
S
I
-
E
S
L
A
D
--------
R
V
G
F
P
-----------------------------
L
-
D
-
K
I
F
V
I
D
G
SKRS
S
H
S
N
A
Y
F
T
G
LPF
T
S
---
K
R
I
V
L
F
D
T
----
L
V
N
S
N
-------------------
S
T
--------
D
E
I
T
---------
A
V
L
A
H
E
I
G
H
---
W
Q
K
N
H
I
V
N
M
V
I
F
S
Q
----------
L
H
T
F
L
I
F
-
S
--
L
F
-
T
------
S
I
Y
-----
R
NSSFY
N
T
F
--SGFV------
D
P
V
I
T
K
E
F
P
I
I
I
----
G
F
M
L
F
N
D
L
------
L
T
P
L
E
-
C
A
M
Q
F
I
M
S
-----
L
I
S
R
T
H
E
Y
Q
A
D
-----
A
Y
A
K
--------------------
K
L
----
G
Y
-
K
Q
N
L
C
R
A
L
I
D
L
Q
I
K
N
L
---
S
TMNV
D
----
P
L
Y
S
----
S
Y
H
Y
S
H
P
T
L
----------------
A
E
R
L
T
A
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
41.99
16%
22
- C5 -
-
2PL2
-
?
B:
[28-221]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
Q
N
----
P
L
R
L
G
V
Q
L
Y
A
L
-
G
R
Y
D
A
A
----
L
T
L
---------
F
E
R
A
LK
E
N
P
Q
-
D
P
E
A
L
Y
---
W
L
A
R
-----
T
Q
-
L
K
L
G
L
V
N
P
A
L
E
-----------
N
G
K
T
L
V
A
R
T
P
R
Y
L
---
G
G
-
Y
M
V
L
S
E
A
---------
Y
V
A
L
YRQAEDRERGK
G
--
Y
-
L
E
Q
A
L
S
V
L
K
-
D
A
E
----------
R
V
N
P
R
Y
A
P
L
H
L
-
Q
R
G
L
V
Y
A
L
L
G
E
R
-------------
D
K
----------
A
E
A
S
L
KQALALEDTPEIRSAL--
A
E
L
Y
L
S
M
G
R
L
D
E
A
L
A
Q
Y
A
K
A
L
E
Q
A
P
K
D
------
L
D
LRV
R
Y
A
S
A
-
L
L
L
--------------------------------------------------------------------------------------------------------
35
HHSearch
41.54
13%
50
- C5 -
-
4R7S
5
?
A:
[43-230]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
----
L
T
N
L
G
T
I
Q
R
R
Q
-
G
K
L
Q
E
A
----
L
I
S
---------
Y
T
S
A
L
S
G
H
T
K
-
N
I
T
I
L
E
---
N
R
A
S
-----
L
Y
-
T
E
L
G
E
T
E
K
A
L
N
-----------
D
Y
N
T
L
L
I
E
N
P
E
H
Q
---
E
A
-
L
Y
C
R
G
L
L
---------
Y
I
Q
L
-----------
Q
--
N
-
Y
M
W
A
E
Q
D
F
D
-
K
I
L
----------
E
V
N
E
K
S
V
R
A
R
L
-
G
H
A
I
L
E
K
M
R
G
N
Y
-------------
D
E
----------
S
E
R
I
F
N
Y
L
I
S
E
M
P
RD
W
I
L
Y
E
G
R
-
A
D
L
Y
F
M
M
G
K
N
A
R
A
M
A
D
I
E
K
V
F
T
E
S
E
P
T
------
A
N
L
Y
V
L
R
G
K
I
-
K
L
A
Q
Y
E
K
E
R
A
-------------------------------------------------------------------------------------------------
25
HHSearch
40.90
14%
-35
- C6 -
-
5SYT
11
FACE1_HUMAN
A:
[232-475]
---------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
K
E
E
I
-
E
V
M
A
K
--------
S
I
D
F
P
-----------------------------
L
--
T
K
V
Y
V
V
E
G
SKRS
S
H
S
----------
N
---
K
R
I
V
L
F
D
T
----
L
L
E
E
Y
S
VLNKEEIKAKVKNK
K
Q
G
C
K
N
--------
E
E
V
L
---------
A
V
L
G
H
E
L
G
H
---
W
K
L
G
H
T
V
K
N
I
I
I
S
Q
----------
M
N
S
F
L
C
F
F
---
L
F
-
A
------
V
L
I
GR
K
E
L
F
-----
A
A
F
G
F
----------
Y
------
D
S
--
Q
----
P
T
L
I
G
L
-
L
I
I
F
Q
FI
F
S
P
-
Y
N
E
V
L
S
F
C
L
T
-----
V
L
S
R
R
F
E
F
Q
A
D
-----
A
F
A
K
--------------------
K
L
G
-----
K
A
K
D
L
Y
S
A
L
I
K
L
N
K
D
N
L
---
G
----
F
PVSD
W
L
F
S
----
M
W
H
Y
S
H
P
P
L
----------------
L
E
R
L
Q
A
L
K
T
M
K
Q
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
40.69
18%
35
- C5 -
-
4C1O
23
?
A:
[25-726]
PKNMF
F
N
A
H
HSPVGAFASFTLGFPGKSGGLDLELGRPPR
Q
N
V
Y
-
I
----
G
V
A
S
L
S
QPG
M
Y
E
V
L
P
F
F
E
A
G
-
D
D
E
S
K
R
Y
D
I
--
E
------
N
P
D
P
N
P
E
K
---
P
Q
I
L
V
P
F
P
N
-----
E
M
I
Q
R
E
-------
F
H
----
V
S
T
D
T
W
K
A
G
D
L
T
F
T
I
Y
-
S
P
V
K
S
V
P
NPDTAK
E
E
D
L
K
-----------------------------
F
-
A
L
V
P
A
V
I
A
E
----
L
T
I
D
N
T
K
G
T
----
S
P
R
R
A
F
F
G
F
E
G
N
D---
P
Y
T
S
M
R
------------------
R
I
--------
D
D
T
C
PP
L
R
G
V
G
Q
G
R
I
T
A
I
V
S
K
H
SD
V
R
S
A
L
H
F
S
L
E
D
I
L
T
T
PLEENWTFGL
G
K
V
G
A
L
I
M
D
--
T
P
A
G
M
K
R
T
Y
Q
F
A
V
-----
C
-----
F
Y
R
S
G
----------
Y
------
A
T
--
A
G
L
D
T
S
Y
-----
F
------
Y
T
R
-
F
-
F
K
N
I
E
E
V
G
-----
K
Y
A
L
D
H
I
E
A
L
K
-----
E
R
A
F
--------------------
Q
S
N
Q
L
I
E
R
D
W
L
S
D
D
Q
K
F
M
M
A
H
A
I
R
S
Y
Y
G
N
----
T
----
Q
L
L
E
Q
EG
K
P
I
W
V
V
N
E
G
E
----------------
Y
R
M
M
N
T
F
D
L
T
V
D
Q
L
F
F
E
L
K
M
N
P
W
T
V
K
N
V
L
D
L
Y
V
E
R
Y
S
Y
Y
D
R
V
R
F
P
G
E
E
K
E
Y
P
G
G
I
S
F
T
HDMGVANTFSRPHYSAYELYGIDGCFSHM
T
H
E
Q
L
V
N
----
W
V
L
C
A
A
V
Y
I
E
Q
T
K
D
W
A
W
R
----
Q
E
K
---------
L
P
I
L
--
E
Q
C
L
-
E
S
M
V
N
R
---
D
H
P
D
----------
P
E
K
R
N
G
V
M
G
-----------
L
D
S
T
R
T
M
G
G
A
E
I
T
---
T
Y
D
S
L
D
V
S
L
G
---------
Q
A
R
N
-----------
N
--
L
-
Y
L
A
G
K
C
W
A
A
Y
V
A
L
----------
E
K
I
F
R
D
T
G
K
E
A
-
L
A
A
L
A
G
E
Q
A
E
K
C
A
A
---------
T
I
V
S
Y
VTEQGYIPA
V
M
G
E
G
------------------
N
D
S
K
I
I
P
A
I
E
G
L
V
F
P
Y
F
T
N
C
H
E
A
L
D
P
H
------
G
R
---
F
G
E
Y
I
-
R
A
L
R
K
H
L
Q
Y
V
--
L
T
E
G
I
CLFPDGGWKISSTSNNSW
L
S
K
I
Y
L
C
Q
F
I
A
R
RILG
W
K
W
D
E
A
G
A
K
A
D
A
A
H
V
A
W
L
T
HPTLSVWSWSDQIIAGEISGSKYYPRGVTS
I
L
W
L
E
E
G
42
HHSearch
40.66
12%
25
- C5 -
-
2VQ2
-
?
A:
[39-217]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
K
N
E
L
A
----
W
L
V
R
A
E
I
Y
Q
Y
L
-
K
V
N
D
K
A
----
Q
E
S
---------
F
R
Q
A
L
S
I
K
P
D
-
S
A
E
I
N
N
---
N
Y
G
W
-----
F
L
C
G
R
L
N
R
P
A
E
S
M
A
-----------
Y
F
D
K
A
L
A
-
D
P
T
Y
P
T
P
Y
I
A
-
N
L
N
K
G
I
C
---------
S
A
K
Q
-----------
G
--
Q
-
F
G
L
A
E
A
Y
L
K
-
R
S
L
----------
A
A
Q
P
Q
F
P
P
A
F
K
-
E
L
A
R
T
K
M
L
A
G
Q
L
-------------
G
D
----------
A
D
Y
Y
F
K
K
Y
Q
S
R
V
EVLQ
A
D
D
L
L
L
G
W
K
I
A
K
A
L
G
N
A
Q
A
A
Y
E
Y
E
A
Q
L
Q
A
N
F
P
Y
S
------
E
E
--------------------------------------------------------------------------------------------------------------------
37
HHSearch
39.01
11%
36
- C5 -
-
4R7S
4
?
A:
[72-246]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
N
I
T
I
----
L
E
N
R
A
S
L
Y
T
E
L
-
G
E
T
E
K
A
----
L
N
D
---------
Y
N
T
L
L
I
E
N
P
E
-
H
Q
E
A
L
Y
---
C
R
G
L
-----
L
Y
-
I
Q
L
Q
N
Y
M
W
A
E
Q
-----------
D
F
D
K
I
L
E
V
N
E
K
S
V
---
R
A
-
R
L
G
H
A
I
L
---------
E
K
M
R
-----------
G
--
N
-
Y
D
E
S
E
R
I
F
N
-
Y
L
I
----------
S
E
M
P
R
D
W
I
L
Y
E
-
G
R
A
D
L
Y
F
M
M
G
K
N
-------------
A
R
----------
A
M
A
D
I
E
K
V
F
T
E
S
E
P
T
A
N
L
Y
V
L
R
-
G
K
I
K
L
A
Q
Y
E
K
E
R
A
A
L
D
F
K
K
A
E
S
M
G
Y
N
K
------
E
V
--------------------------------------------------------------------------------------------------------------------