@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKM2: (2017-10-27 )
MKILITGANTGIGFATAEQLVKQGQHVILACRNPQKAQEAQNKLRSLDQGQVDVASLDLNSLELTQKAAEEIADKYGSLDVLINNAGLFSKTKQLTVDGFEQKFGVNYLGHFLLTQKLLPVLKQFPQAHIIHLASIAHWVGSIKPNKFRAEGFYNPLFYYGQSKLANLLFSNALAEQLADSSITNNALHPGGVASDIYRDLPKPVYAAMKVGLVPTSVPAKLITEMATGDTWQNRNGEYVSAHMPDWKSSHAKNQQLARDLYQQSMNLVEKFL
Atome Classification :
(20 SA)
.........-----10........20..-......30........40.....------...50........60........70........80........---90--.--.---....--..-----------100......----.110.----......120...-....130...-....140..--.-------------.--...150--------.----........160.......170......--.180--..--.......190---..-.....---------.200.......210......--.220.......230..----......240.......250.......260.......270.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
K
I
L
I
TGAN-----TGI
G
F
A
T
A
E
Q
L
V
KQ-G
Q
H
V
I
L
A
CRN
P
Q
K
A
Q
E
A
Q
N
K
L
R
S------LDQGQ
V
D
V
A
SLDL
N
S
L
E
L
T
Q
K
A
A
E
E
I
A
D
K
YGS
L
D
V
L
INNAGLF---SK--T--
K
---
Q
L
TV--D
G
-----------
F
E
Q
K
F
G
V
N
Y
----
L
G
H
F
L
----
L
T
Q
K
L
L
P
V
L
K
QF-
P
Q
A
H
I
I
H
L
A
S
-
I
A
H
W
V
GSIK--P-------------N--
K
F
RA----------E----GFY
N
P
L
F
YY
G
Q
S
K
L
A
N
L
L
F
S
N
A
L
A
E
Q
L
--AD----SS--ITNNALHPG----G
V
-
A
S
D
I
Y
---------
R
DL
P
K
P
V
Y
A
A
M
KVGLVPTS
V
--
P
A
K
L
I
T
E
MATGDT-WQ----NRNG
E
Y
V
SAHMPDWKSSHA
K
N
Q
Q
L
A
R
D
L
Y
Q
Q
S
M
N
L
V
E
K
FL
21
HHSearch
89.92
35%
-48
- C1 -
-
3RD5
2
?
A:
[17-288]
R
T
V
V
I
T
G
A
N
-----
S
G
L
G
A
V
T
A
R
E
L
A
R
R
-
G
A
T
V
I
M
A
V
R
D
T
R
K
G
E
A
A
A
R
T
M
----------
A
G
Q
V
E
V
R
E
L
D
L
Q
D
L
S
S
V
R
R
F
A
D
G
V
----
S
G
A
D
V
L
I
N
N
A
G
I
M
---
A
V
--
P
--
Y
---
A
L
T
V
--
D
G
-----------
F
E
S
Q
I
G
T
N
H
----
L
G
H
F
A
----
L
T
N
L
L
L
P
R
L
T
-----
D
R
V
V
T
V
S
S
-
M
A
H
W
P
G
R
I
N
--
L
-------------
E
--
D
L
N
W
R---------
S
----
R
R
Y
S
P
W
L
A
Y
S
Q
S
K
L
A
N
L
L
F
T
S
E
L
Q
R
R
L
--
T
A
A
G--
S
P
--
L
R
A
L
A
A
H
P
G
----
Y
S
-
H
T
N
L
--------------------------
A
T
D
A
D
F
G
A
R
Q
T
L
Y
A
A
S
Q
D
L
-
P
G
DSFV
G
P
R
F
G
Y
L
G
R
T
Q
P
V
G
R
S
R
R
A
K
D
A
G
M
A
A
A
L
W
A
L
S
E
Q
L
T
K
T
E
-
10
PsiBlast_PDB
73.95
25%
-58
- C1 -
-
4Z0T
2
?
A:
[19-253]
---
L
V
T
G
A
S
-----
R
G
I
G
Y
F
L
S
L
E
L
A
K
R
-
G
A
H
V
I
A
V
A
R
T
V
G
G
L
E
E
L
D
D
E
I
R
K
------
L
G
S
-
S
A
T
L
V
P
L
D
I
T
D
M
E
A
L
D
R
L
G
G
T
I
H
E
R
W
G
K
L
D
I
L
V
A
N
A
G
I
L
GTI
S
P
--
I
--
G
---
H
V
E
A
--
K
T
-----------
F
E
K
V
M
N
I
N
V
----
T
S
V
W
R
----
L
I
R
S
V
D
P
L
L
R
A
S
-
D
A
G
R
A
I
M
L
S
S
G
V
A
H
---------------------------
S
C
----------
R
----
A
F
W
G
P
---
Y
A
A
S
K
A
A
V
E
V
M
A
R
C
W
A
E
E
T
--
K
K
----
M
K
--
L
K
I
N
S
V
N
P
G
----
A
T
-
R
T
A
M
R
AQAMPGEDP
E
T
L
P
T
P
Q
S
V
A
E
K
I
--
V
K
L
A
D
--
P
K
L
E
V
----
T
G
K
L
-
F
D
----
V
R
Q
D
R
F
L
D
Y
H
M
P
----------------------------
1
PsiBlast_PDB
73.51
41%
0
- C- -
-
3RD5
1
?
A:
[19-218]
--
V
V
I
T
G
A
N
-----
S
G
L
G
A
V
T
A
R
E
L
A
R
R
-
G
A
T
V
I
M
A
V
R
D
T
R
K
G
E
A
A
A
R
T
M
----------
A
G
Q
V
E
V
R
E
L
D
L
Q
D
L
S
S
V
R
R
----
F
A
D
G
V
S
G
A
D
V
L
I
N
N
A
G
I
M
---
A
V
--
P
--
Y
---
A
L
T
V
--
D
G
-----------
F
E
S
Q
I
G
T
N
H
----
L
G
H
F
A
----
L
T
N
L
L
L
P
R
L
T
D
-----
R
V
V
T
V
S
S
-
M
A
H
W
P
G
R
I
N
--
L
-------------
E
DL
N
W
R
S
----------
R
-----
R
Y
S
P
W
L
A
Y
S
Q
S
K
L
A
N
L
L
F
T
S
E
L
Q
R
R
L
T
A
A
G
----
S
P
--
L
R
A
L
A
A
H
P
G
-------------------------------------------------------------------------------------------------------
36
HHSearch
73.06
22%
-81
- C1 -
-
5JY1
3
?
A:
[15-202]
R
V
A
L
V
T
G
A
G
-----
G
G
I
G
R
G
V
A
R
S
F
G
N
E
-
G
A
A
V
I
I
A
E
I
N
E
S
T
G
R
Q
V
E
Q
E
I
R
E
------
M
-
G
G
R
S
L
F
V
K
T
D
V
T
S
K
A
S
I
E
A
A
V
R
S
A
V
E
Q
F
G
S
L
D
I
L
V
N
N
A
F
V
P
---
T
P
NV
L
L-
E
---
E
K
T
D
--
E
M
-----------
L
E
Q
T
L
T
T
S
L
----
W
A
T
W
W
----
A
M
R
A
A
F
V
P
M
R
E
R
-
R
W
G
R
I
V
N
F
Y
S
-
I
D
T
E
T
G
-------------------------------------------
A
W
L
H
G
D
Y
N
T
A
K
A
G
I
V
G
L
T
R
S
A
A
S
E
W
--
G
R
----
F
N
--
I
T
V
N
A
I
A
P
T
----
A
M
-
G
A
T
F
F
-------------------------------------------------------------------------------------------
3
PsiBlast_PDB
71.83
28%
-85
- C1 -
-
3RIH
9
?
A:
[43-233]
-
S
V
L
V
T
G
G
T
-----
K
G
I
G
R
G
I
A
T
V
F
A
R
A
-
G
A
N
V
A
V
A
A
R
S
P
R
E
L
S
S
V
T
A
E
L
G
E
------
L
G
A
G
N
V
I
G
V
R
L
D
V
S
D
P
G
S
C
A
D
A
A
R
T
V
V
D
A
F
G
A
L
D
V
V
C
A
N
A
G
I
F
---
P
E
--
A
--
R
LD-
T
M
T
P
--
E
Q
-----------
L
S
E
V
L
D
V
N
V
----
K
G
T
V
Y
----
T
V
Q
A
C
L
A
P
L
T
A
S
-
G
R
G
R
V
I
L
T
S
S
-
I
T
G
P
V
T
G
------------------------------------------
Y
P
G
W
S
H
Y
G
A
S
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
L
--
A
P
----
R
G
--
V
T
V
N
A
I
L
P
G
----
N
I
-
L
T
E
G
L
---------
V
D
M
-------------------------------------------------------------------------------
27
HHSearch
70.79
25%
-10
- C1 -
-
1N5D
1
CBR1_PIG
A:
[5-275]
R
V
A
L
V
T
G
A
N
-----
K
G
I
G
F
A
I
V
R
D
L
C
R
Q
F
A
G
D
V
V
L
T
A
R
D
V
A
R
G
Q
A
A
V
K
Q
L
Q
A
------
E
-
G
L
S
P
R
F
H
Q
L
D
I
I
D
L
Q
S
I
R
A
L
C
D
F
L
R
K
E
Y
G
G
L
D
V
L
V
N
N
A
A
I
A
---
F
Q
--
L
DN
P
---
T
P
F
H
--
I
Q
-----------
A
E
L
T
M
K
T
N
F
----
M
G
T
R
N
----
V
C
T
E
L
L
P
L
I
K
P
---
Q
G
R
V
V
N
V
S
S
-
T
E
G
V
R
A
L
N
E
CS
P
E
L
Q
Q
K
F
K
SETIT
E
E
--
E
L
V
G
L
M
N
K
F
V
E
D
T
K
N
GVHR
K
E
G
W
S
D
S
T
Y
G
V
T
K
I
G
V
S
V
L
S
R
I
Y
A
R
K
L
--
R
E
Q
RAG
D
K
--
I
L
L
N
A
C
C
P
G
----
W
V
-
R
T
D
M
G
---------
G
P
K
A
------------
P
K
S
P
E
V
G
A
E
T
P
V
Y
L
A
L
L
P
S
D
A
E
----
G
P
H
G
Q
F
V
T
D
K
K
V
V
E
--------------------------
8
PsiBlast_PDB
69.56
27%
-90
- C1 -
-
3AI3
3
?
A:
[11-188]
---
V
I
T
G
S
S
-----
S
G
I
G
L
A
I
A
E
G
F
A
K
E
-
G
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
K
E
------
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
P
E
G
V
D
A
V
V
E
S
V
R
S
S
F
G
G
A
D
I
L
V
N
N
A
G
-----
T
G
--
S
--
N
---
E
T
I
M
--
E
A
-----------
A
D
E
K
W
Q
F
Y
W
E
L
LV
M
A
A
V
R
----
L
A
R
G
L
V
P
G
M
R
A
R
-
G
G
G
A
I
I
H
N
A
S
-
I
C
----
A
V
Q
--
P
-------------
L
----------------------
W
Y
E
P
I
--
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
----
D
N
--
I
R
V
N
C
I
N
P
G
-------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
68.99
26%
-44
- C1 -
-
1VL8
1
?
A:
[25-238]
---
L
V
T
G
G
S
-----
R
G
L
G
F
G
I
A
Q
G
L
A
E
A
-
G
C
S
V
V
V
A
S
R
N
L
E
E
A
S
E
A
A
Q
K
L
T
E
------
K
Y
G
V
E
T
M
A
F
R
C
D
V
S
N
Y
E
E
V
K
K
L
L
E
A
V
K
E
K
F
G
K
L
D
T
V
V
N
A
A
G
I
N
---
R
R
H
P
A
--
E
---
E
F
P
L
--
D
E
-----------
F
R
Q
V
I
E
V
N
L
----
F
G
T
Y
Y
----
V
C
R
E
A
F
S
L
L
R
E
S
-
D
N
P
S
I
I
N
I
G
S
-
L
T
V
E
E
V
T
M
---
P
-------------
N
--------------------------
I
S
A
Y
A
A
S
K
G
G
V
A
S
L
T
K
A
L
A
K
E
W
--
G
R
----
Y
G
--
I
R
V
N
V
I
A
P
G
W
Y
R
T
K
M
-
T
E
A
V
F
---------
S
D
P
E
K
L
D
Y
M
L
K
R
I
P
L
G
R
T
G
V
--
P
E
D
L
--------------------------------------------------------
45
HHSearch
68.50
25%
-83
* C1 *
-
5IG2
1
?
B:
[15-205]
K
V
A
V
I
T
G
A
G
-----
S
G
F
G
R
A
F
A
E
K
G
A
S
L
-
G
M
K
L
V
L
A
D
V
D
E
G
A
L
A
R
T
V
D
T
L
R
A
------
A
-
G
A
E
V
I
G
V
R
T
D
V
S
N
G
A
Q
V
Q
A
L
A
D
A
A
L
E
A
F
G
K
V
H
L
L
F
N
N
A
G
V
G
---
A
G
--
G
FL
W
---
E
S
S
A
--
N
D
-----------
W
A
W
V
F
G
V
N
V
----
M
G
V
A
H
----
G
V
R
V
F
A
P
I
M
L
G
Q
N
E
A
A
H
I
V
N
T
A
S
-
V
A
G
L
L
S
-------------------------------------------
P
P
S
M
G
I
Y
N
A
S
K
H
A
V
V
S
L
T
E
T
L
Y
H
D
L
--
R
N
----
A
G
GE
V
G
C
S
L
L
C
P
A
----
F
V
-
P
T
G
I
A
---------
D
---------------------------------------------------------------------------------
2
PsiBlast_PDB
68.00
29%
-59
- C1 -
-
4NBU
1
?
A:
[17-208]
---
I
I
T
G
A
A
-----
N
G
I
G
L
E
A
A
R
V
F
M
K
E
-
G
A
K
V
V
I
A
D
F
N
E
A
A
G
K
E
A
V
E
A
----------
N
P
G
V
V
F
I
-
R
V
D
V
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
G
K
I
D
I
L
I
N
N
A
G
I
T
RD-
S
M
--
L
--
S
---
K
M
T
V
--
D
Q
-----------
F
Q
Q
V
I
N
V
N
L
----
T
G
V
F
H
----
C
T
Q
A
V
L
P
Y
M
A
E
Q
-
G
K
G
K
I
I
N
T
S
S
-
V
T
G
T
Y
G
N
V
G
--
Q
-------------
T
--
N
--------------------------
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
--
A
R
----
K
G
--
I
N
V
N
A
V
A
P
G
----
F
T
-
E
T
A
M
V
---------
A
E
V
P
E
K
V
I
E
K
M
K
----------------------------------------------------------------------
46
HHSearch
67.42
25%
-83
- C1 -
-
5IG2
1
?
A:
[15-205]
K
V
A
V
I
T
G
A
G
-----
S
G
F
G
R
A
F
A
E
K
G
A
S
L
-
G
M
K
L
V
L
A
D
V
D
E
G
A
L
A
R
T
V
D
T
L
R
A
------
A
-
G
A
E
V
I
G
V
R
T
D
V
S
N
G
A
Q
V
Q
A
L
A
D
A
A
L
E
A
F
G
K
V
H
L
L
F
N
N
A
G
V
G
---
A
G
--
G
FL
W
---
E
S
S
A
--
N
D
-----------
W
A
W
V
F
G
V
N
V
----
M
G
V
A
H
----
G
V
R
V
F
A
P
I
M
L
G
Q
N
E
A
A
H
I
V
N
T
A
S
-
V
A
G
L
L
S
-------------------------------------------
P
P
S
M
G
I
Y
N
A
S
K
H
A
V
V
S
L
T
E
T
L
Y
H
D
L
--
R
N
----
A
G
GE
V
G
C
S
L
L
C
P
A
----
F
V
-
P
T
G
I
A
---------
D
---------------------------------------------------------------------------------
5
PsiBlast_PDB
67.37
27%
-92
- C1 -
-
3AI2
1
?
A:
[11-188]
---
V
I
T
G
S
S
-----
S
G
I
G
L
A
I
A
E
G
F
A
K
E
-
G
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
K
E
------
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
P
E
G
V
D
A
V
V
E
S
V
R
S
S
F
G
G
A
D
I
L
V
N
N
A
G
-----
T
G
--
S
--
N
---
E
T
I
M
--
E
A
-----------
A
D
E
K
W
Q
F
Y
W
----
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
-
G
G
G
A
I
I
H
N
A
S
-
I
C
----
A
V
Q
--
P
-------------
L
----------------------
W
Y
E
P
I
--
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
----
D
N
--
I
R
V
N
C
I
N
P
G
-------------------------------------------------------------------------------------------------------
32
HHSearch
66.45
25%
-27
- C1 -
-
3E03
-
?
C:
[7-243]
K
T
L
F
I
T
G
A
S
-----
R
G
I
G
L
A
I
A
L
R
A
A
R
D
-
G
A
N
V
A
I
A
A
K
S
A
V
A
N
P
K
L
P
G
T
I
H
S
A
A
A
A
V
N
A
A
G
G
Q
G
L
A
L
K
C
D
I
R
E
E
D
Q
V
R
A
A
V
A
A
T
V
D
T
F
G
G
I
D
I
L
V
N
N
A
S
A
I
---
W
L
R-
G
T-
L
---
D
T
P
M
--
K
R
-----------
F
D
L
M
Q
Q
V
N
A
----
R
G
S
F
V
----
C
A
Q
A
C
L
P
H
L
L
Q
A
-
P
N
P
H
I
L
T
L
A
P
-
P
P
S
L
N
P
A
-----------------------------------------
W
W
G
A
H
T
G
Y
T
L
A
K
M
G
M
S
L
V
T
L
G
L
A
A
E
F
--
G
P
----
Q
G
--
V
A
I
N
A
L
W
P
R
----
T
V
I
A
T
D
A
I
---------
N
M
L
P
G
V
D
A
------
A
A
C
R
R
P
E
I
M
A
D
A
A
H
A
V
L
T
R
E
A
-
A
-----
G
F
H
G
Q
F
L
I
D
D
------------------------------
4
PsiBlast_PDB
66.34
27%
-92
- C1 -
-
3AI1
-
?
A:
[11-188]
---
V
I
T
G
S
S
-----
S
G
I
G
L
A
I
A
E
G
F
A
K
E
-
G
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
K
E
------
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
P
E
G
V
D
A
V
V
E
S
V
R
S
S
F
G
G
A
D
I
L
V
N
N
A
G
-----
T
G
--
S
--
N
---
E
T
I
M
--
E
A
-----------
A
D
E
K
W
Q
F
Y
W
----
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
-
G
G
G
A
I
I
H
N
A
S
-
I
C
----
A
V
Q
--
P
-------------
L
----------------------
W
Y
E
P
I
--
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
----
D
N
--
I
R
V
N
C
I
N
P
G
-------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
66.23
27%
-61
- C1 -
-
2P68
-
FABG_AQUAE
A:
[11-202]
---
L
V
T
G
S
T
-----
R
G
I
G
R
A
I
A
E
K
L
A
S
A
-
G
S
T
V
I
I
T
G
T
S
G
E
R
A
K
A
V
A
E
E
I
A
N
------
K
Y
G
V
K
A
H
G
V
E
M
N
L
L
S
E
E
S
I
N
K
A
F
E
E
I
Y
N
L
V
D
G
I
D
I
L
V
N
N
A
G
I
----
T
R
--
D
--
K
LFL
R
M
S
L
--
L
D
-----------
W
E
E
V
L
K
V
N
L
----
T
G
T
F
L
----
V
T
Q
N
S
L
R
K
M
I
K
Q
-
R
W
G
R
I
V
N
I
S
S
-
V
V
G
F
T
G
N
V
---------------------------------------
G
Q
V
N
----
Y
S
T
T
K
A
G
L
I
G
F
T
K
S
L
A
K
E
L
--
A
P
----
R
N
--
V
L
V
N
A
V
A
P
G
----
F
I
-
E
T
D
M
T
---------
A
V
L
S
E
E
I
---------------------------------------------------------------------------
31
HHSearch
65.17
25%
-25
- C1 -
-
3E03
-
?
B:
[7-243]
K
T
L
F
I
T
G
A
S
-----
R
G
I
G
L
A
I
A
L
R
A
A
R
D
-
G
A
N
V
A
I
A
A
K
S
A
V
A
N
P
K
L
P
G
T
I
H
S
A
A
A
A
V
N
A
A
G
G
Q
G
L
A
L
K
C
D
I
R
E
E
D
Q
V
R
A
A
V
A
A
T
V
D
T
F
G
G
I
D
I
L
V
N
N
A
S
A
I
---
W
L
R-
G
T-
L
---
D
T
P
M
--
K
R
-----------
F
D
L
M
Q
Q
V
N
A
----
R
G
S
F
V
----
C
A
Q
A
C
L
P
H
L
L
Q
A
-
P
N
P
H
I
L
T
L
A
P
-
P
P
S
L
N
P
A
-----------------------------------------
W
W
G
A
H
T
G
Y
T
L
A
K
M
G
M
S
L
V
T
L
G
L
A
A
E
F
--
G
P
----
Q
G
--
V
A
I
N
A
L
W
P
R
----
T
V
I
A
T
D
A
I
---------
N
M
L
P
G
V
D
A
------
A
A
C
R
R
P
E
I
M
A
D
A
A
H
A
V
L
T
R
E
A
-
A
-----
G
F
H
G
Q
F
L
I
D
D
------------------------------
11
PsiBlast_PDB
64.42
27%
-59
- C1 -
-
2PNF
3
FABG_AQUAE
A:
[11-202]
---
L
V
T
G
S
T
-----
R
G
I
G
R
A
I
A
E
K
L
A
S
A
-
G
S
T
V
I
I
T
G
T
S
G
E
R
A
K
A
V
A
E
E
I
A
N
------
K
Y
G
V
K
A
H
G
V
E
M
N
L
L
S
E
E
S
I
N
K
A
F
E
E
I
Y
N
L
V
D
G
I
D
I
L
V
N
N
A
G
I
----
T
R
--
D
--
K
LFL
R
M
S
L
--
L
D
-----------
W
E
E
V
L
K
V
N
L
----
T
G
T
F
L
----
V
T
Q
N
S
L
R
K
M
I
K
Q
-
R
W
G
R
I
V
N
I
S
S
-
V
V
G
F
T
G
N
V
---------------------------------------
G
Q
V
N
----
Y
S
T
T
K
A
G
L
I
G
F
T
K
S
L
A
K
E
L
--
A
P
----
R
N
--
V
L
V
N
A
V
A
P
G
----
F
I
-
E
T
D
M
T
---------
A
V
L
S
E
E
I
---------------------------------------------------------------------------
20
PsiBlast_PDB
64.30
28%
-78
- C1 -
-
4NBW
1
?
A:
[9-212]
---
I
I
T
G
A
A
-----
N
G
I
G
R
A
T
A
L
E
F
A
Q
A
-
G
Y
H
V
V
-
A
W
D
L
A
E
E
A
G
A
A
L
I
A
E
I
A
------
D
A
G
G
S
A
D
F
A
R
V
D
V
S
A
A
E
S
V
E
A
A
V
A
E
I
I
A
E
H
G
R
V
D
V
L
V
N
N
A
G
I
L
---
H
D
--
G
--
Q
---
L
V
K
V
--
K
G
GEVVKKMA
E
A
Q
F
D
A
V
I
S
V
N
L
----
K
G
V
F
L
----
C
T
Q
A
V
A
P
H
M
I
A
A
-
K
Y
G
R
I
L
N
A
S
S
-
V
V
G
L
Y
G
N
F
G
--
Q
-------------
T
--
N
Y
V
A
--------------------------
A
K
S
G
V
I
G
M
T
K
V
W
A
R
E
L
--
G
R
----
Y
G
--
I
T
V
N
A
I
A
P
G
----
F
I
-
A
T
E
M
V
---------
Q
Q
M
P
E
R
V
L
E
A
M
-----------------------------------------------------------------------
17
PsiBlast_PDB
64.24
28%
-41
- C1 -
-
4DQX
-
?
A:
[31-208]
---
I
V
T
G
G
G
-----
S
G
I
G
R
A
T
A
E
L
F
A
K
N
-
G
A
Y
V
V
V
A
D
V
N
E
D
A
A
V
R
V
A
N
E
I
G
S
------
K
A
F
G
----
V
R
V
D
V
S
S
A
K
D
A
E
S
M
V
E
K
T
T
A
K
W
G
R
V
D
V
L
V
N
N
A
G
F
G
---
T
T
--
G
--
N
---
V
V
T
I
P
E
E
T
-----------
W
D
R
I
M
S
V
N
V
----
K
G
I
F
L
----
C
S
K
Y
V
I
P
V
M
R
R
N
-
G
G
G
S
I
I
N
T
T
S
------------------------------
Y
T
A
----------
T
----
S
A
I
A
D
R
T
A
Y
V
A
S
K
G
A
I
S
S
L
T
R
A
M
A
M
D
H
--
A
K
----
E
G
--
I
R
V
N
A
V
A
P
G
----
T
I
-
D
S
----------------------------------------------------------------------------------------------
33
HHSearch
62.28
22%
-6
- C1 -
-
5JC8
6
?
A:
[18-213]
K
V
A
L
V
T
G
A
G
CIGPG
W
G
N
G
R
A
I
A
V
R
F
A
E
E
-
G
A
H
V
I
A
V
D
R
D
L
A
S
M
D
A
T
L
E
L
V
R
A
------
A
-
G
G
S
V
T
P
C
L
C
D
V
T
D
S
A
S
V
E
R
L
V
A
D
S
V
A
R
C
G
R
V
D
I
L
V
N
N
V
G
A
P
---
S
P
--
G
G
P
V
---
A
L
D
E
--
A
Q
-----------
W
A
M
Q
L
E
L
N
L
----
T
T
A
F
L
----
M
C
K
Y
V
L
P
V
M
E
Q
Q
-
G
G
G
A
I
V
N
I
A
S
-
T
S
G
I
R
W
------------------------------------------
T
G
A
A
Q
V
G
Y
A
A
A
K
A
G
M
I
Q
M
G
R
V
V
A
V
E
Y
--
A
A
----
K
N
--
V
R
V
N
S
V
V
P
G
----
L
L
-
H
T
P
M
V
---------
D
---------------------------------------------------------------------------------