@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0064: (2016-03-12 )
MTVETIDVFSPVELYLLLSPIEAQHLFGVPDKLTFLLKGEDVFAEGFDRLKSKGILNEAGELTDGGGFLIDSLIEYYQSKKYVRMNQLMFAFLEKTPNELLVMIEITPQKEYRFERMNKIYALEMIKDFFPLIRREPGERETEFLKEELTNEERKRATAFDPEKNFISMEFFHVDEEPKEKNNAKYYKQYLAFEMEDKLMMVDVVNDTYYRGSQYALLKLLFDELEFPYEEAK
Atome Classification :
(20 SA)
------------------------------------.........10..----....-..20.-..-.----....30---....--..-..----------------.40-.....-....-50........60---------....--.....70.------....--...80..-----.--------------------------...---..90.....-.---..100.....--..110-------------------.......120.......-..130.......140.......150-........160-------...----------------------......170.........180.......--------190.----......--200..------.....210...--..------...220....----...230.----------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------M
T
V
E
T
I
DVFS
P
V
E
----
L
Y
L
L
-LSPI
E
-
A
Q
-
H
----LFGVP----
D
K
L
T
--
F
L
-
L
K----------------G
E
--
D
V
F
A
E
-
G
F
D
R
-
L
K
SKGILNEAG----------ELTD--G
G
G
F
L
I
D
S
------
L
I
E
Y
--
Y
Q
SK
K
Y
V
-----
R
--------------------------
M
N
Q
---
L
M
F
A
F
L
E
KT-P---N
E
L
L
V
M
I
E
IT--PQ
K
E
Y
-------------------
R
F
E
R
M
N
K
I
--
Y
A
L
E
M
I
K
-
D
F
F
P
L
I
RREPG
E
R
E
T
E
F
L
K
E
E
LT
N
--
E
E
R
KRATAF---------DPE----------------------K
N
F
I
S
M
E
--
F
F
HVDEEPKEKN
N
A
K
Y
Y
K
Q
--------
Y
L
A
F----EMED
K
L
--
M
M
V
D
V------VNDTYYR-G
S
Q
--
Y
A
------
L
L
K
L
L
F
D
E
LE----FPYEEAK----------------------------------------
39
Fugue
81.31
17%
-26
- C1 -
4PWO
1
?
A:
[1-250]
------------------------------------
T
Q
A
E
K
T
A
T
D
L
P
P
G
----
F
S
G
K
-
A
G
S
V
N
-
A
T
-
P
----
G
T
K
G
L
----
D
G
P
T
--
P
L
-
A
D
----------------
G
S
F-
D
A
T
I
F
-
G
P
A
K
E
L
K
S
A
D
D
I
L
N
V
H
----------
R
R
N
A
--
K
D
P
F
A
V
G
A
VDAP
L
V
I
T
E
F
S
D
F
E
C
P
F
C
A
-----
R
--------------------------
W
S
N
---
Q
T
E
P
T
L
M
E
E
Y
V
---
S
K
G
L
V
R
I
E
W
N
D
L
P
V
N
G
E
-------------------
H
A
L
A
A
A
K
A
--
G
R
A
A
A
A
Q
-
G
K
F
D
E
F
R
K
A
L
F
E
A
S
R
N
--
V
S
G
H
P
N
--
N
T
L
K
D
F
E
R
F
---------
A
R
N
----------------------
A
G
V
K
D
M
E
--
R
F
--
S
R
E
A
Q
D
S
T
Y
D
E
V
L
A
K
--------
A
A
D
Y
----
A
H
G
L
G
V
SG
T
P
A
F
V
------
V
G
T
Q
Y
I
S
-
G
A
Q
P
T
E
E
------
F
I
K
V
I
E
S
E
L
K
K
SP
T
F
S
T
P
S
S
H
----------------------------------------
31
Fugue
76.69
21%
-20
- C5 -
1AA7
-
M1_I34A1
A:
[1-158]
-----------------------------------------
M
S
L
L
T
E
V
E
----
T
Y
V
L
--
S
I
I
P
-
S
G
----------
P
----
L
K
A
E
--
I
A
-
Q
R
----------------
L
E
--
D
V
F
A
-----------------
G
----------
K
N
T
D
-------
L
E
V
------
L
M
E
W
--
L
K
T
R
P
I
L
-----
S
--------------------------
P
L
T
K
G
I
L
G
F
V
F
T
L
T
V
-
P
---
S
E
-------------------------------------------------------------
R
G
L
Q
R
R
R
F
V
Q
N
A
L
N
G
NG
D
P
N
N
M
D
K
A
V
---------
K
L
Y
----------------------
R
K
L
K
R
E
I
--
T
F
H
G
A
K
E
I
S
L
S
Y
S
A
G
A
L
A
S
--------
C
M
G
L
----
I
Y
-------------------
N
R
M
G
A
-
V
T
T
--
E
V
------
A
F
G
L
V
C
A
T
C
E
----
Q
I
A
D
S
Q
-----------------------------------------
38
Fugue
74.93
11%
-40
- C4 -
4F03
2
?
A:
[2-252]
--------------------------------------------
A
Q
P
I
V
----
F
Y
D
I
-
P
S
N
E
R
-
I
K
-
H
SPWS
P
N
T
W
K
----
I
R
Y
A
--
L
N
-
Y
K
----------------
G
L
--
K
Y
K
T
E
-
W
V
E
Y
-
P
D
I
A
G
V
V
Q
K
L
G
GKPTE-----
K
T
P
D
--
G
R
D
H
Y
T
L
P
------
V
I
Y
D
--
P
N
T
K
K
V
V
-----
E
--------------------------
D
S
A
---
A
I
A
K
Y
L
D
E
T
Y
P
---
D
T
P
K
L
F
P
A
G
T
--
D
A
F
Q
A
-------------------
A
F
L
D
F
A
W
P
--
V
L
G
F
P
V
F
M
L
V
I
L
D
T
A
N
S
L
L
P
R
S
H
D
Y
F
R
S
T
R
E
Q
--
K
F
G
K
K
L
E
E
L
---------
A
T
E
----------------------
E
E
W
A
K
V
E
A
G
L
A
K
L
K
G
Y
L
D
A
N
G
K
G
N
D
L
L
L
MGAQGGIT
Y
S
D
I
----
Q
I
A
S
F
F
--
V
W
A
K
I
------
I
W
G
E
G
S
E
-
K
W
K
--
R
L
I
S
LHDG
K
W
A
Q
F
Y
A
Q
F
T
-----
K
F
E
Q
V
D
----------------------------------------
19
HHSearch
60.80
17%
-57
- C3 -
1BJA
1
MOTA_BPT4
A:
[12-87]
------------------------------------------
D
V
L
N
E
K
T
----
A
T
I
L
-
I
T
I
A
K
-
K
D
-
F
-----
I
T
A
A
----
E
V
R
E
--
V
H
P
D
L
----------------
G
N
--
A
V
V
N
S
-
N
I
G
V
-
L
I
K
K
G
L
V
E
K
S
G
D
G
L
-------
I
I
T
G
--
E
A
Q
D
I
I
S
N
------
A
A
T
L
--
Y
A
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
58.67
15%
-52
- C3 -
2PEX
1
?
A:
[44-121]
-------------------------------------------
D
L
T
Y
P
Q
----
Y
L
V
M
-
L
V
L
W
E
-
T
D
--------
E
R
S
----
V
S
E
I
G
E
R
L
-
Y
L
----------------
D
S
--
A
T
L
T
P
-
L
L
K
R
-
L
Q
A
A
G
L
V
T
R
T
R
V
I
I
-------
A
L
T
E
--
T
G
R
A
L
R
S
K
------
A
G
A
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
58.10
29%
-32
- C3 -
4M0M
1
?
A:
[655-740]
--------------------------------------------------------------
E
-
V
L
-
N
----
F
F
N
I
P
L---
P
K
L
H
--
S
E
-
V
K
----------------
E
Q
I
A
D
K
L
K
E
-
R
L
V
D
-
L
K
E
K
G
M
G
N
D
V
N
----------
A
I
T
R
--
E
L
G
K
A
R
E
D
------
L
I
E
H
--
Y
K
K
T
------------------------------------
G
E
---
L
D
-
K
I
I
N
K
S
-
M
---
E
E
L
L
V
A
R
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
57.77
14%
-41
* C5 *
3J9T
-
VA0D_YEAST
Q:
[1-345]
------------MEGVYFNIDNGFIEGVVRGYRNGL
L
S
N
N
Q
Y
I
N
L
T
Q
C
D
TLED
L
K
L
Q
-
L
S
S
T
D
Y
G
N
-
F
----
L
S
S
V
S
SESL
T
T
S
L
--
I
Q
-
E
Y
----------------
A
S
--
S
K
L
Y
H
-
E
F
N
Y
-
I
R
D
Q
S
S
-
G
S
T
R
----------
K
F
M
D
YI
T
Y
G
Y
M
I
D
N
------
V
A
L
M
--
I
T
G
T
I
H
D
-----
R
DKGEILQRCHPLGWFDTLPTLSVATD
L
E
S
---
L
Y
E
T
V
L
V
D
T
-
P
LAP
Y
F
K
N
C
F
D
T
A
E
--
E
L
D
D
M
-------------------
N
I
E
I
I
R
N
K
--
L
Y
K
A
Y
L
E
-
D
F
Y
N
F
V
T
E
E
I
P
E
P
A
K
E
C
M
Q
T
L
L
G
F
--
E
A
D
R
R
S
I
N
I
---------
A
L
N
SLQSSDIDPDLKSDLLPNIGKL
Y
P
L
A
T
F
H
--
L
A
Q
A
Q
D
F
E
G
V
R
A
A
L
A
N
V
Y
E
--------
Y
R
G
F
LETG
N
L
E
D
H
F
--
Y
Q
L
E
M
ELCRDA
F
T
Q
Q
F
A
I
-
S
T
V
--
W
A
------
W
M
K
S
K
E
Q
E
V
R
----
N
I
T
W
I
A
E
CIAQNQRERINNYISVY-----------------------
37
Fugue
57.20
13%
-36
* C4 *
4XNV
15
P2RY1_HUMAN (first)
A:
[38-382]
SFKCA
L
T
K
T
GF
Q
F
Y
Y
L
P
A
V
Y
I
L
V
F
I
I
G
F
L
G
N
S
V
A
I
W
M
F
V
F
H
M
K
P
W
S
G
I
S
----
V
Y
M
F
N
L
A
L
A
D
-
F
L
-
Y
----
V
L
T
L
P
----
A
L
I
F
--
Y
Y
-
F
N
----------------
K
T
--
D
-
W
I
F
-
G
D
A
M
-
C
K
L
Q
R
F
I
F
H
V
N
----------
L
Y
-----
G
S
I
L
F
L
T
------
C
I
S
A
--
H
R
Y
S
G
V
V
YPKSL
G
--------------------------
R
L
K
---
K
K
N
A
I
C
I
S
V
-
L
---
V
W
L
I
V
V
V
A
I
S
--
P
I
L
F
Y
S
G
T
G
V
R
KNKTITCYDTTSD
E
Y
L
R
S
Y
F
I
--
Y
S
M
C
T
T
V
-
A
M
F
C
V
P
L
V
L
I
L
G
C
Y
G
L
I
V
R
A
L
I
Y
K
--
M
K
K
Y
T
C
T
V
C
G
Y
I
Y
N
PEDG
D
P
D
----------------------
N
G
V
N
P
G
T
--
D
F
K
D
I
V
C
P
L
C
G
V
G
K
D
Q
F
E
E
--------
V
E
E
P
----
L
R
R
K
S
I
--
Y
L
V
I
I
------
V
L
T
V
F
A
V
S
Y
I
P
--
F
H
------
V
M
K
T
M
N
L
R
A
R
----
L
D
F
Q
T
P
A
M
C
A
F
N
D
R
V
Y
A
T
Y
Q
V
T
R
G
L
A
S
L
N
S
C
V
N
P
I
L
Y
F
LAGDTFRRR
23
HHSearch
51.64
10%
-63
- C3 -
3BRO
2
?
A:
[31-109]
-------------------------------------------
D
L
T
G
T
Q
----
M
T
I
I
-
D
Y
L
S
R
-
N
K
N
K
----
E
V
L
Q
R
----
D
L
E
S
--
E
F
-
S
I
----------------
K
S
--
S
T
A
T
V
-
L
L
Q
R
-
M
E
I
K
K
L
L
Y
R
K
V
SGKDSR
Q
K
C
L
K
L
T
K
--
K
A
N
K
L
E
T
I
------
I
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
51.13
31%
13
- C3 -
4KZY
-
?
R:
[38-104]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
I
I
--
P
S
K
K
L
-------------------
R
----
N
K
I
A
G
Y
V
T
H
L
M
K
-
R
----
I
Q
R
G
P
----
V
R
G
I
S
I
K
L
Q
E
--
E
E
R
E
R
R
D
N
Y
---------
V
P
E
----------------------
V
S
A
L
D
Q
E
--
I
I
E
V
D
P
D
T
K
E
------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
51.06
31%
13
- C3 -
4KZZ
-
?
R:
[38-104]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
I
I
--
P
S
K
K
L
-------------------
R
----
N
K
I
A
G
Y
V
T
H
L
M
K
-
R
----
I
Q
R
G
P
----
V
R
G
I
S
I
K
L
Q
E
--
E
E
R
E
R
R
D
N
Y
---------
V
P
E
----------------------
V
S
A
L
D
Q
E
--
I
I
E
V
D
P
D
T
K
E
------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
50.91
31%
13
- C3 -
4KZX
-
?
R:
[38-104]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
I
I
--
P
S
K
K
L
-------------------
R
----
N
K
I
A
G
Y
V
T
H
L
M
K
-
R
----
I
Q
R
G
P
----
V
R
G
I
S
I
K
L
Q
E
--
E
E
R
E
R
R
D
N
Y
---------
V
P
E
----------------------
V
S
A
L
D
Q
E
--
I
I
E
V
D
P
D
T
K
E
------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
45.24
31%
36
- C3 -
5A2Q
-
?
R:
[38-104]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
I
I
--
P
S
K
K
L
-------------------
R
----
N
K
I
A
G
Y
V
T
H
L
M
K
-
R
----
I
Q
R
G
P
----
V
R
G
I
S
I
K
L
Q
E
--
E
E
R
E
R
R
D
N
Y
---------
V
P
E
----------------------
V
S
A
L
D
Q
E
--
I
I
E
V
D
P
D
T
K
E
------------------------------------------------------------------------------------------------------------------------------
36
Fugue
40.18
12%
2
- C2 -
1SGM
-
YXAF_BACSU
A:
[5-188]
---------------------------------------------------------------------------
G
D
----
S
R
E
K
--
I
L
-
H
T
----------------
A
S
--
R
L
S
Q
L
Q
G
Y
H
A
-
T
G
L
N
Q
I
V
K
E
S
G
-------------------
A
P
K
G
S
------
L
Y
H
F
--
F
P
N
G
K
E
E
-----
L
--------------------------
A
I
E
---
A
V
T
Y
T
G
K
I
V
-
E
---
H
L
I
Q
Q
S
M
D
E
S
--
S
D
P
V
E
-------------------
A
I
Q
L
F
I
K
K
--
T
A
S
Q
F
D
N
-
T
E
S
I
-----
K
G
I
P
V
G
L
L
A
S
E
T
A
L
I
--
S
E
P
L
R
T
V
C
M
---------
K
V
F
----------------------
K
S
W
E
A
V
F
--
A
R
K
L
M
E
N
G
F
A
E
E
E
A
N
Q
L
G
T
--------
L
I
N
S
----
M
I
E
G
G
I
--
M
L
S
L
T
------
N
K
D
K
-------------------
T
P
L
L
L
I
A
E
----
Q
I
P
V
L
V
R
----------------------------------------
21
HHSearch
39.14
18%
65
* C3 *
2XAU
-
PRP43_YEAST
A:
[487-521]
------------------------------------------------------------------------------------------------------------
A
P
--
E
T
M
M
R
-
A
L
E
E
-
L
N
Y
L
A
C
L
D
D
E
G
----------
N
L
T
P
--
L
G
R
L
A
S
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
38.54
24%
12
- C3 -
2QEZ
3
?
A:
[379-448]
------------------------------------------------
N
----
L
S
V
L
-
L
T
A
A
G
-
C
N
-
F
----
I
M
G
I
P
----
H
G
D
D
--
V
M
-
L
N
Y
Q
TTG
Y
H
E
T
A
T
L
R
E
L
F
G
L
--
K
P
I
K
E
-
F
D
Q
W
-
M
E
K
M
G
F
S
E
-
N
G
----------
K
L
T
S
--
R
A
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
36.17
16%
69
- C3 -
1Z91
-
OHRR_BACSU
A:
[67-113]
------------------------------------------------------------------------------------------------------------
D
S
--
G
T
L
T
P
-
M
L
K
R
-
M
E
Q
Q
G
L
I
T
R
K
R
SEEDER
S
V
L
I
S
L
T
E
--
D
G
A
L
L
K
E
K
------
A
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
32.53
31%
62
- C3 -
4JMJ
-
DUS11_HUMAN
A:
[6-59]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
W
K
-
D
Y
L
P
V
G
Q
R
M
P
G
T
R
F
I
A
F
K
V
P
L
Q
K
S
--
F
E
K
K
L
A
-------------
P
E
----------------------
E
C
F
S
P
L
D
--
L
F
N
K
I
R
E
Q
N
E
E
-----------------------------------------------------------------------------------------------------------------------------
18
HHSearch
30.92
23%
68
- C3 -
3I4U
1
A:
[17-53]
-------------------------------------------------------------------------------------------------------------
M
--
E
T
L
I
T
-
A
M
E
Q
-
L
Y
T
L
G
A
L
D
D
E
G
----------
L
L
T
R
--
L
G
R
R
M
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
30.45
31%
60
- C3 -
4MBB
-
DUS11_HUMAN
A:
[10-63]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
W
K
-
D
Y
L
P
V
G
Q
R
M
P
G
T
R
F
I
A
F
K
V
P
L
Q
K
S
--
F
E
K
K
L
A
-------------
P
E
----------------------
E
C
F
S
P
L
D
--
L
F
N
K
I
R
E
Q
N
E
E
-----------------------------------------------------------------------------------------------------------------------------