@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1724: (2016-03-28 )
MNENLITITGLTKKYRKRKPLNDINLSLQKGKIIGLLGPNGAGKTTLLNAISGLLKPTSGTINLAENSKIAYLPSEDFLPNMVICDYFRIYHSFFPDFDQEKAKQMIRSFGINIKENTKYLSKGNAAKVMLALILCRDVDLYLLDEPFSEIDLISRDDLIKSIATFLKEDATLVVTTHLIQDMEMMFDEIIFLKRGKIIEQIDTETLREEYRKSVMDYYREVFGHA
Atome Classification :
(20 SA)
.........10.....-.--..--20........30........40........50........60.-----.-----....------------------------.-----.-----70.....-.-----..-80...--....-----..90...-------.----.---------.---..---------100...---....-----110-..---.--..----..--.120-----------.........130.......140.......150......---.---160......-.-170.......180.......190.......200.......210-.-......220....----------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNE
N
L
I
T
ITGL
T
K
K
Y
R-K--RK--PLNDI
N
L
S
LQK
G
K
I
I
G
L
LGPNGA
G
K
T
T
L
L
N
A
I
S
G
L
LKPTS
G
T
I
-----
N
-----LAEN------------------------
S
-----
K
-----
I
A
YLPSE-D-----FL-P-
N
M
V
--
I
C
D
Y
-----
F
R
I
Y
H
S
F-------F----P---------D---F
D
---------
Q
E
K
A
K
Q
---
M
I
R
S
-----FG--IN---I--KE----N
T
--
K
Y-------------LSKG
N
A
A
K
V
M
L
A
L
I
L
CRDV
D
L
Y
LLDEP
F
S
EIDLI
S
R
D
D
---
L
---
I
K
S
I
A
T
F
L
K-E-D
A
T
L
V
V
T
T
H
L
I
Q
D
M
E
M
M
F
D
E
I
I
F
L
KRG
K
I
I
E
QI
D
T
E
T
L
R
E
E
Y
R
-
K
-
S
V
M
D
Y
Y
R
E
V
FGHA----------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
90.66
31%
-122
- C1 -
1VPL
2
?
A:
[16-249]
-----
V
V
V
K
D
L
R
K
R
I
G
-
K
--
K
E
--
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
FGK
N
-----
V
V
E
E
------------------------
P
-----
H
E
V
R
K
L
I
S
Y
L
P
E
E
A
G
-----
A
Y
-
R
-
N
M
Q
--
G
I
E
Y
-----
L
R
F
V
A
G
F
-------
Y
----
A
---------
S
---
S
S
---------
S
E
I
E
E
M
---
V
E
R
A
T
E
I
A
G
L
G
--
E
K
---
I
--
K
D
----
R
V
--
S
T
-------------
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
---
V
---
R
K
I
L
K
Q
A
S
Q
-
E
-
G
L
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
T
G
T
V
E
E
L
K
E
R
Y
K
A
Q
-
N
I
E
E
V
F
E
E
V
--------------------------------------------------------------------------------------------------------------
47
HHSearch
90.30
32%
-123
- C1 -
1VPL
2
?
A:
[14-251]
---
G
A
V
V
V
K
D
L
R
K
R
I
G
-
K
--
K
E
--
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
-----
T
-----
V
F
G
K
NVVEE
P
H
E
V
R
--------------
K
-----
L
-----
I
S
Y
L
P
E
E
-
A
-----
G
A
Y
R
-
N
M
Q
--
G
I
E
Y
-----
L
R
F
V
A
G
F
-------
Y
----
A
---------
S
S
S
S
E
I
---------
E
E
M
V
E
R
---
A
T
E
I
-----
A
G
--
L
G
EK-
I
--
K
D
----
R
V
--
S
T
-------------
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
---
V
---
R
K
I
L
K
Q
A
S
Q
-
E
-
G
L
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
T
G
T
V
E
E
L
K
E
R
Y
K
-
A
Q
N
I
E
E
V
F
E
E
V
V
K
------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
87.60
29%
-137
- C1 -
2IT1
-
?
A:
[4-214]
-----
I
K
L
E
N
I
V
K
K
F
G
-
N
--
F
T
--
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
-----
Y
-----
F
D
E
K
------------------------
D
-----------
V
T
E
L
P
P
K
-
D
RN
V
G
L
V
F
-
Q
-
N
W
A
--
L
Y
P
H
-----
M
T
V
Y
K
N
I
A
------
F
----
P
L
E
L
R
KAP
R
E
E
---
I
D
---------
K
-
K
V
R
E
---
V
A
K
M
-----
L
H
--
I
D
KL-
L
--
N
R
----
Y
P
--
W
Q
-------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
---
V
---
R
A
E
L
K
R
L
Q
K
-
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
--------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
84.18
30%
-114
- C1 -
1OXV
7
?
A:
[4-228]
-----
I
I
V
K
N
V
S
K
V
F
K
-
K
--
G
K
VV
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
-----
Y
FDDRL
V
A
S
N
------------------------
G
-----
K
-----
L
-
I
V
P
P
E
-
D
-----
R
K
-
I
-
G
M
V
--
F
Q
T
W
------
A
L
Y
P
N
L
T
A
F
E
N
I
A
F
----
P
---------
L
---
T
N
---------
M
K
M
S
K
E
---
E
I
R
K
----------
R
---
V
--
E
E
----
V
A
--
K
I
L
DIHHVLNHFPRE
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
---
V
K
E
V
Q
S
R
L
----
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
-------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
83.29
27%
-115
- C1 -
1OXX
21
?
K:
[2-233]
---
V
R
I
I
V
K
N
V
S
K
V
F
K
-
K
GK
V
V
--
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
-----
Y
-----
F
D
D
R
LVASNGKLIVPPED----------
R
-----
K
-----
I
G
M
V
F
Q
T
-
W
-----
A
L
Y
P
-
N
L
T
--
A
F
E
N
-----
I
A
F
P
L
T
N
-------
M
----
K
MSK------
E
---
E
I
---------
R
K
R
V
E
E
---
V
A
K
I
-----
L
D
--
I
H
HV-
L
--
N
H
----
F
P
--
R
E
-------------
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
---
A
---
R
A
L
V
K
E
V
Q
S
R
L
-
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
--------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
83.20
30%
-115
- C1 -
1OXX
21
?
K:
[4-228]
-----
I
I
V
K
N
V
S
K
V
F
K
-
K
--
G
K
VV
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
-----
Y
FDDRL
V
A
S
N
------------------------
G
-----
K
-----
L
-
I
V
P
P
E
-
D
-----
R
K
-
I
-
G
M
V
--
F
Q
T
W
------
A
L
Y
P
N
L
TAFENIA
F
----
P
---------
L
---
T
N
---------
M
K
M
S
K
E
---
E
I
R
K
----------
R
---
V
--
E
E
----
V
A
--
K
I
LDIHHVLNHFPRE
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
ARA
L
---
V
K
E
V
Q
S
R
L
----
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
-------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
83.18
28%
-119
- C1 -
3D31
-
?
A:
[1-220]
----
M
I
E
I
E
S
L
S
R
K
W
K
-
N
---
F
--
S
L
D
N
L
S
L
K
V
E
S
G
E
Y
F
V
I
L
G
P
T
G
A
G
K
T
L
F
L
E
L
I
A
G
F
H
V
P
D
S
G
R
I
-----
L
-----
L
D
G
K
DVTDLSPEK---------------
H
-----
D
-----
I
A
F
V
Y
Q
N
-
Y
-----
S
L
F
P
-
H
M
N
--
V
K
K
N
-----
L
E
F
G
M
R
M
-------
K
----
K
---------
I
---
K
D
---------
P
K
R
V
L
D
---
T
A
R
D
-----
L
K
--
I
E
HL-
L
--
D
R
----
N
P
--
L
T
-------------
L
S
G
G
E
Q
Q
R
V
A
L
A
R
A
L
V
T
N
P
K
I
L
L
L
D
E
P
L
S
A
L
D
P
R
T
Q
E
N
---
A
---
R
E
M
L
S
V
L
H
K
K
N
-
K
L
T
V
L
H
I
T
H
D
Q
T
E
A
R
I
M
A
D
R
I
A
V
V
M
D
G
K
L
I
Q
V
G
K
P
E
E
I
F
E
K
P
V
--------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
83.04
30%
-117
- C1 -
1OXT
-
?
A:
[4-228]
-----
I
I
V
K
N
V
S
K
V
F
K
-
K
--
G
K
VV
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
-----
Y
FDDRL
V
A
S
N
------------------------
G
-----
K
-----
L
-
I
V
P
P
E
-
D
-----
R
K
-
I
-
G
M
V
--
F
Q
T
W
------
A
L
Y
P
N
L
T
A
F
E
N
I
A
F
----
P
---------
L
---
T
N
---------
M
K
M
S
K
E
---
E
I
R
K
----------
R
---
V
--
E
E
----
V
A
--
K
I
L
DIHHVLNHFPRE
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
---
V
K
E
V
Q
S
R
L
----
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
-------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
82.41
30%
-114
- C1 -
1OXU
7
?
A:
[4-228]
-----
I
I
V
K
N
V
S
K
V
F
K
-
K
--
G
K
VV
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
-----
Y
FDDRL
V
A
S
N
------------------------
G
-----
K
-----
L
-
I
V
P
P
E
-
D
-----
R
K
-
I
-
G
M
V
--
F
Q
T
W
------
A
L
Y
P
N
L
T
A
F
E
N
I
A
F
----
P
---------
L
---
T
N
---------
M
K
M
S
K
E
---
E
I
R
K
----------
R
---
V
--
E
E
----
V
A
--
K
I
L
DIHHVLNHFPRE
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
---
V
K
E
V
Q
S
R
L
----
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
-------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
82.39
30%
-113
- C1 -
1OXS
18
?
C:
[4-228]
-----
I
I
V
K
N
V
S
K
V
F
K
-
K
--
G
K
VV
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
-----
Y
FDDRL
V
A
S
N
------------------------
G
-----
K
-----
L
-
I
V
P
P
E
-
D
-----
R
K
-
I
-
G
M
V
--
F
Q
T
W
------
A
L
Y
P
N
L
TAFENIA
F
----
P
---------
L
---
T
N
---------
M
K
M
S
K
E
---
E
I
R
K
----------
R
---
V
--
E
E
----
V
A
--
K
I
LDIHHVLNHFPRE
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
ARA
L
---
V
K
E
V
Q
S
R
L
----
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
-------------------------------------------------------------------------------------------------------------------------------
54
Fugue
81.97
24%
-109
- C1 -
1Z47
1
?
A:
[11-355]
-
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
--
A
R
--
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
-----
W
-----
I
-
G
G
------------------------
K
-----
R
-----
V
T
D
L
P
P
Q
-
K
-----
R
N
-
V
-
G
L
V
--
F
Q
N
Y
ALFQH
M
T
V
Y
D
N
V
-------
S
----
F
---------
G
---
L
R
E
K
RVP
K
D
E
M
D
A
R
V
R
E
---
L
L
R
F
-----
M
R
--
L
E
---
S
YA
N
R
----
F
P
--
H
E
-------------
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
---
L
---
R
T
F
V
R
Q
V
H
D
-
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
G
-
T
----
L
F
V
A
S
F
I
G
E
S
N
V
W
T
R
A
V
Q
NG
R
I
E
V
AG
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
33
HHSearch
81.97
27%
-122
- C1 -
2IT1
-
?
A:
[2-225]
---
V
E
I
K
L
E
N
I
V
K
K
F
G
-
N
--
F
T
--
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
-----
Y
-----
F
D
E
K
DVTELPPKD---------------
R
-----
N
-----
V
G
L
V
F
Q
N
-
W
-----
A
L
Y
P
-
H
M
T
--
V
Y
K
N
-----
I
A
F
P
L
E
L
-------
R
----
K
AP
R
------
E
---
E
I
---------
D
K
K
V
R
E
---
V
A
K
M
-----
L
H
--
I
D
KL-
L
--
N
R
----
Y
P
--
W
Q
-------------
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
---
V
---
R
A
E
L
K
R
L
Q
K
E
L
-
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
---------------------------------------------------------------------------------------------------------------------------
44
HHSearch
81.85
25%
-124
- C1 -
1B0U
4
HISP_SALTY
A:
[5-258]
---
N
K
L
H
V
I
D
L
H
K
R
Y
G
-
G
--
H
E
--
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
-----
I
-----
V
N
G
Q
NI
N
L
V
R
D
KDGQLKVAD
K
N
Q
L
R
L
L
R
T
-----
R
-----
L
T
M
V
F
Q
H
-
F
-----
N
L
-
W
S
H
M
T
--
V
L
E
N
-----
V
M
E
A
P
I
Q
-------
V
LGLS
K
---------
H
---
D
A
---------
R
E
R
A
L
K
---
Y
L
A
K
-----
V
G
--
I
D
ERA
Q
--
G
K
----
Y
P
--
V
H
-------------
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
---
V
---
L
R
I
M
Q
Q
L
A
E
-
E
-
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
-
S
P
R
L
Q
Q
F
L
K
G
S
L
K
------------------------------------------------------------------------------------------------------------
28
HHSearch
80.99
25%
-116
- C1 -
1Z47
1
?
A:
[12-238]
--
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
--
A
R
--
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
-----
W
-----
I
G
G
K
RVTDLPPQK---------------
R
-----
N
-----
V
G
L
V
F
Q
N
-
Y
-----
A
L
F
Q
-
H
M
T
--
V
Y
D
N
-----
V
S
F
G
L
R
E
-------
K
----
R
VP
K
------
D
---
E
M
---------
D
A
R
V
R
E
---
L
L
R
F
-----
M
R
--
L
E
SY-
A
--
N
R
----
F
P
--
H
E
-------------
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
---
L
---
R
T
F
V
R
Q
V
H
D
E
M
-
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
G
--------------------------------------------------------------------------------------------------------------------------
36
HHSearch
80.77
25%
-122
- C1 -
2YYZ
3
?
A:
[2-225]
---
P
S
I
R
V
V
N
L
K
K
Y
F
G
-
K
--
V
K
--
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
-----
Y
-----
F
D
D
V
LVNDIPPKY---------------
R
-----
E
-----
V
G
M
V
F
Q
N
-
Y
-----
A
L
Y
P
-
H
M
T
--
V
F
E
N
-----
I
A
F
P
L
R
A
-------
R
----
R
ISK------
D
---
E
V
---------
E
K
R
V
V
E
---
I
A
R
K
-----
L
L
--
I
D
NL-
L
--
D
R
----
K
P
--
T
Q
-------------
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
---
M
---
R
A
E
I
K
H
L
Q
Q
E
L
-
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
S
P
---------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
80.38
29%
-138
- C1 -
1V43
-
?
A:
[13-234]
-----
V
K
L
E
N
L
T
K
R
F
G
-
N
--
F
T
--
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
-----
Y
-----
F
G
D
R
------------------------
D
-----------
V
T
Y
L
P
P
K
-
D
-----
R
N
-
I
-
S
M
V
FQ---
H
-----
M
T
V
Y
E
N
I
A
------
F
----
P
LK-------
K
---
F
P
---------
K
D
E
I
D
K
---
R
V
R
W
-----
A
A
E
L
L
Q
---
I
--
E
E
LLNR
Y
P
--
A
Q
-------------
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
---
M
R
A
E
I
K
K
L
Q
Q
K
L
K
----
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
-
Q
I
G
S
P
T
--------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
80.20
29%
-135
- C1 -
1VCI
1
?
A:
[13-234]
-----
V
K
L
E
N
L
T
K
R
F
G
-
N
--
F
T
--
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
-----
Y
-----
F
G
D
R
------------------------
D
-----------
V
T
Y
L
P
P
K
-
D
-----
R
N
-
I
-
S
M
V
F
Q---
H
-----
M
T
V
Y
E
N
I
A
------
F
----
P
LK-------
K
---
F
P
---------
K
D
E
I
D
K
---
R
V
R
W
-----
A
A
E
L
L
Q
---
I
--
E
E
LLNR
Y
P
--
A
Q
-------------
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
---
M
R
A
E
I
K
K
L
Q
Q
K
L
K
----
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
-
Q
I
G
S
P
T
--------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
80.13
23%
-123
- C1 -
2OLJ
4
?
A:
[22-263]
--
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
-
S
--
L
E
--
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
-----
I
-----
I
D
G
I
NLKAKDTN
L
N
K
V
R
-----------
E
-----
E
-----
V
G
M
V
F
Q
R
-
F
-----
N
L
-
F
P
H
M
T
--
V
L
N
N
-----
I
T
L
A
P
M
K
-------
V
----
R
KWP
R
-----
E
---
K
A
---------
E
A
K
A
M
E
---
L
L
D
K
-----
V
G
--
L
K
DK-
A
--
H
A
----
Y
P
--
D
S
-------------
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
---
V
---
L
S
V
M
K
Q
L
A
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
-
H
E
R
T
K
A
F
L
S
K
V
F
-------------------------------------------------------------------------------------------------------------
42
HHSearch
79.54
24%
-124
- C1 -
3GFO
1
ECFA3_CLOP1
A:
[4-236]
-
E
D
Y
I
L
K
V
E
E
L
N
Y
N
Y
S
-
D
G-
T
H
--
A
L
K
G
I
N
M
N
I
K
R
G
E
V
T
A
I
L
G
G
N
G
V
G
K
S
T
L
F
Q
N
F
N
G
I
L
K
P
S
S
G
R
I
-----
L
-----
F
D
N
K
PIDYS
R
K
G
I
M
K
L
R
-----------
E
-----
S
-----
I
G
I
V
F
Q
D
-
P
DN---
Q
L
-
F
-
S
A
S
--
V
Y
Q
D
-----
V
S
F
G
A
V
N
-------
M
----
K
LP
E
------
D
---
E
I
---------
R
K
R
V
D
N
---
A
L
K
R
-----
T
G
--
I
E
HL-
K
--
D
K
----
P
T
--
H
C
-------------
L
S
F
G
Q
K
K
R
V
A
I
A
G
V
L
V
M
E
P
K
V
L
I
L
D
E
P
T
A
G
L
D
P
M
G
V
S
E
---
I
---
M
K
L
L
V
E
M
Q
K
E
L
-
G
I
T
I
I
I
A
T
H
D
I
D
I
V
P
L
Y
C
D
N
V
F
V
M
K
E
G
R
V
I
L
Q
G
N
P
K
E
V
F
A
E
K
E
--------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
79.22
23%
-118
- C1 -
4RVC
-
?
A:
[2-225]
---
T
L
L
E
V
K
D
L
S
G
G
Y
T
-
A
--
Q
N
--
V
L
E
D
V
T
F
V
V
D
R
G
E
M
V
A
L
I
G
L
N
G
A
G
K
S
T
T
I
K
H
I
I
G
L
M
E
P
R
R
G
A
I
-----
S
I
NGYR
L
A
D
G
------------------------
P
E
T
Y
R
R
Q
-----
F
A
Y
I
P
E
T
-
P
-----
V
L
Y
E
-
E
L
T
--
L
E
E
H
-----
L
R
L
A
A
M
A
-------
Y
----
G
---------
L
---
S
E
---------
A
E
Y
E
R
R
L
P
P
L
L
R
E
-----
F
R
--
L
E
---
R
--
R
L
----
S
S
FP
A
H
-------------
F
S
K
G
M
K
Q
K
V
M
I
V
C
A
F
L
L
E
P
P
L
Y
I
I
D
E
P
F
L
G
L
D
P
L
A
I
H
A
---
L
---
L
E
R
M
N
E
Q
K
A
-
K
-
G
A
G
I
L
L
S
T
H
I
L
A
T
A
E
R
Y
C
D
S
F
V
I
L
H
N
G
R
V
K
A
K
G
T
L
D
D
I
R
R
Q
F
---------------------------------------------------------------------------------------------------------------------------