@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2824: (2016-04-07 )
VFNIQTFNAIAKEGLKTFDLEKYVIDANQPADGILLRSYNLHDFDFPETVKAVARAGAGVNNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILEGTEWVKELPAEDDVEQKVEAGKKAFAGTELAGKKLGIIGLGAIGALVANDALSLGMDVVGYDPFVSVDTAWRISKEVERAMTIEEVLATCDYLTVHVPLTDKTRGMFNADTLQLVKDNAVLLNFSRGELVDSASVKEALDDGLLRLYITDFATKELLNHKKVHVFPHLGASTEEAETNCAKMAAKELQSYLETGSIKNSVNFPNVEMPYNGHPRIGICHKNIPNMVGQITTELGKYSLNILDMINRSKNEYAYTLIDIDKETQANLEQLKQDLLAVQGVLRVRVIEPLGVTV
Atome Classification :
(23 SA)
------------.........10........20..-----...--------.-----------.----.-30.......---.-40...--...---...50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180........190.......200.......210.......220.......230.......240......-----.250.------------..------.-----------.-----.-------.260.-......---270.......280.......290.......300......---------------------------------------------------------------------------------------------------------------------------.310------.-......320.......-------330....-...340......--.350.......360..--.....370...----....380------.........390...--------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------VFN
I
Q
T
F
N
A
I
A
K
EGLKTFD
L
E
K
Y
-----
V
ID--------A-----------N----Q-PA
D
G
I
L
L
R
S---Y-N-LHD--FD
F
---
P
E
T
V
K
A
V
A
R
AGAGVNNIPVENCSEK
G
I
V
V
F
NTPGA
N
A
N
A
V
K
E
L
V
L
A
S
L
F
V
SARPILEG
T
E
W
V
K
ELPAE
D
D
V
E
Q
K
V
E
AGKKAFAGTELAG
K
K
L
G
I
I
G
L
G
A
I
G
A
L
V
A
N
D
A
L
S
LGMDVVGYDPFVSV
D
T
A
W
R
I
S
K
E
V
E
-
R
A
M
T
I
E
E
V
L
ATC
D
Y
L
T
V
H
VPLTDKTRGMFN
A
D
T
L
Q
L
VKD
N
A
V
L
L
NFSRGELV
D
S
A
S
V
K
E
A
L
DD
G
L
L
R
-----
L
Y
I
T
D
------------
F
A
------
T
-----------
K
-----
E
-------
L
LNHK-
K
V
H
V
FP---HLGAST
E
E
A
E
T
N
C
A
K
M
A
A
K
E
L
Q
S
Y
L
E
TGSIKNSVNFPNV---------------------------------------------------------------------------------------------------------------------------EMPY------N-GHP
R
I
G
I
CHK
N
I
P
N
M
V
-------
G
Q
I
T
T
E
L
-
G
K
Y
S
L
N
I
L
D
M
I
N--RSKN
E
Y
A
Y
T
L
I
DIDK
E
--
T
Q
A
N
L
E
Q
L
K
Q
D
----
L
L
A
V
Q
--------
G
V
L
R
V
R
V
IEPLGVTV--------------------------------------------------------------------------------------------------------
44
HHSearch
90.12
28%
-99
- C2 -
1YGY
1
SERA_MYCTU
A:
[4-528]
------------
L
P
V
V
L
I
A
D
K
L
A
P
S
T
V
A
A
L
G
D
-
Q
V
-----
E
V
R
--------
W
V
DGPD
R
D
K
L
L
A
A
----
V
P
E
A
D
A
L
L
V
R
S
---
A
T
T
-
V
D
A
--
E
V
L
A
A
-
A
P
K
L
K
I
V
A
R
A
G
V
G
L
D
N
V
D
V
D
A
A
T
A
R
G
V
L
V
V
N
A
P
T
S
N
I
H
S
A
A
E
H
A
L
A
L
L
L
A
A
S
R
Q
I
P
A
A
D
A
S
L
R
E
H
----------
T
W
K
R
S
S
F
S
G
T
E
I
F
G
K
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
A
F
G
A
Y
V
V
A
Y
D
P
Y
V
S
P
A
R
A
A
--
Q
L
G
I
E
--
L
L
S
L
D
D
L
L
A
R
A
D
F
I
S
V
H
L
P
K
T
P
E
T
A
G
L
I
D
K
E
A
L
A
K
T
K
P
G
V
I
I
V
N
A
A
R
G
G
L
V
D
E
A
A
L
A
D
A
I
T
G
G
H
V
R
-----
A
A
G
L
D
------------
V
F
ATEPCT
D
-----------
S
-----
P
-------
L
F
E
L
A
-
Q
V
V
V
T
P
---
H
L
G
A
S
T
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
R
L
A
L
A
G
E
F
V
P
D
A
V
N
V
G
G
G
VVNEEV
A
P
W
L
D
L
V
R
K
L
G
V
L
A
G
V
L
SDELPV
S
L
S
V
Q
V
R
G
ELAAEEV
E
V
L
R
L
S
A
L
R
G
L
F
SAVIEDAVTFVN
A
P
A
L
A
A
E
RG
V
T
A
E
I
C
K
A
SESPNHR
S
V
V
D
V
R
A
V
G
ADG
S
V
V
T
V
S
G
T
L
Y
G
PQLSQKIV
Q
I
N
G
R
H
F
D
L
R
A
-
Q
G
I
N
L
I
I
H
Y
V
D
R
P
G
A
L
-------
G
K
I
G
T
L
L
-
G
T
A
G
V
N
I
Q
A
A
Q
L
S
E
D
A
E
G
P
G
A
T
I
L
L
R
L
D
Q
D
--
V
P
---
D
D
V
R
T
A
----
I
A
A
A
V
--------
D
A
Y
K
L
E
V
V
D
L
-------------------------------------------------------------------------------------------------------------
43
HHSearch
89.78
28%
-84
- C2 -
3K5P
4
?
A:
[15-416]
------------
R
I
N
V
L
L
L
E
G
I
S
Q
T
A
V
E
Y
F
K
S
S
G
Y
-----
T
N
V
--------
T
H
L
P
K
A
L
D
K
A
--
D
L
I
K
A
I
S
S
A
H
I
I
G
I
R
S
---
R
T
Q
-
L
T
E
--
E
I
F
A
A
-
A
N
R
L
I
A
V
G
C
F
S
V
G
T
N
Q
V
E
L
K
A
A
R
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
I
I
M
L
M
R
R
I
F
P
R
S
V
S
A
H
A
G
----------
G
W
E
K
T
A
I
G
S
R
E
V
R
G
K
T
L
G
I
V
G
Y
G
N
I
G
S
Q
V
G
N
L
A
E
S
L
G
M
T
V
R
Y
Y
D
T
S
D
K
L
Q
Y
-----
G
N
V
K
-
P
A
A
S
L
D
E
L
L
K
T
S
D
V
V
S
L
H
V
P
-----
S
K
L
I
T
E
A
K
L
R
K
M
K
K
G
A
F
L
I
N
N
A
R
G
S
D
V
D
L
E
A
L
A
K
V
L
Q
E
G
H
L
A
-----
G
A
A
I
D
------------
V
F
------
P
VEPASNG
E
R
F
S
T
-----
P
-------
L
Q
G
L
E
-
N
V
I
L
T
P
---
H
I
G
G
S
T
E
E
A
Q
E
R
I
G
T
E
V
T
R
K
L
V
E
Y
S
D
V
G
S
T
V
G
A
V
N
F
P
Q
V
---------------------------------------------------------------------------------------------------------------------------
Q
L
P
P
------
R
P
T
G
T
R
F
M
H
V
H
E
N
R
P
G
I
L
-------
N
S
L
M
N
V
F
-
S
H
H
H
I
N
I
A
S
Q
F
L
--
Q
T
D
G
E
V
G
Y
L
V
M
E
A
D
G
V
G
E
A
S
---
D
A
V
L
Q
E
----
I
R
E
I
P
--------
G
T
I
R
A
R
L
L
Y
--------------------------------------------------------------------------------------------------------------
42
HHSearch
89.22
29%
-91
- C2 -
1SC6
1
SERA_ECOLI
A:
[4-404]
------------
K
I
K
F
L
L
V
E
G
V
H
Q
K
A
L
E
S
L
R
A
A
G
Y
-----
T
N
I
E
F
H
K
G
A
L
D
D
E
----------
Q
L
K
E
S
I
R
D
A
H
F
I
G
L
R
S
---
R
-
T
H
L
T
E
--
D
V
I
N
A
-
A
E
K
L
V
A
I
G
A
F
A
I
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
L
L
L
L
L
R
G
V
P
E
A
N
A
K
A
H
R
G
----------
V
G
N
-----
S
F
E
A
R
G
K
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
I
E
N
K
L
P
L
-----
G
N
A
T
-
Q
V
Q
H
L
S
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
A
D
A
L
A
S
K
H
L
A
-----
G
A
A
I
D
------------
V
--------DPFT-------
S
-----
P
-------
L
A
E
F
D
-
N
V
L
L
T
P
---
H
I
G
G
S
T
Q
E
A
Q
E
N
I
G
L
E
V
A
G
K
L
I
K
Y
S
D
N
G
S
T
L
S
A
V
N
F
P
E
V
---------------------------------------------------------------------------------------------------------------------------
S
L
P
L
------
H
-
G
G
R
R
L
M
H
I
H
E
N
R
P
G
V
L
-------
T
A
L
N
K
I
F
-
A
E
Q
G
V
N
I
A
A
Q
Y
L
--
Q
T
S
A
Q
M
G
Y
V
V
I
D
I
E
A
D
E
D
V
A
---
E
K
A
L
Q
A
----
M
K
A
I
P
--------
G
T
I
R
A
R
L
L
Y
--------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
85.83
28%
-89
- C2 -
3K5P
4
?
A:
[83-415]
------------------------------------------------------------------------------------------------------
A
V
G
C
F
S
V
G
T
N
Q
V
E
L
K
A
A
R
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
I
I
M
L
M
R
R
I
-----
F
P
R
S
V
S
A
H
A
G
G
W
E
K
T
A
I
G
S
R
-----
E
V
R
G
K
T
L
G
I
V
G
Y
G
N
I
G
S
Q
V
G
N
L
A
E
S
L
G
M
T
V
R
Y
Y
D
T
S
D
K
L
Q
Y
G
-----
N
V
K
-
P
A
A
S
L
D
E
L
L
K
T
S
D
V
V
S
L
H
V
P
-----
S
K
L
I
T
E
A
K
L
R
K
M
K
K
G
A
F
L
I
N
N
A
R
G
S
D
V
D
L
E
A
L
A
K
V
L
Q
E
G
H
L
A
-----
G
A
A
I
D
VFPVEPASNG
E
R
F
S
------
T
-----------
P
-------------
L
Q
G
L
E
-
N
V
I
L
T
P
---
H
I
G
G
S
T
E
E
A
Q
E
R
I
G
T
E
V
T
R
K
L
V
E
Y
S
D
V
G
S
T
V
G
A
V
N
F
P
Q
V
---------------------------------------------------------------------------------------------------------------------------
Q
L
P
P
------
R
P
T
G
T
R
F
M
H
V
H
E
N
R
P
G
I
L
-------
N
S
L
M
N
V
F
-
S
H
H
H
I
N
I
A
S
Q
F
L
--
Q
T
D
G
E
V
G
Y
L
V
M
E
A
D
G
V
--
G
E
A
S
-
D
A
V
L
Q
E
----
I
R
E
I
P
--------
G
T
I
R
A
R
L
L
---------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
83.29
29%
-94
- C2 -
1YBA
6
SERA_ECOLI
A:
[85-409]
-------------------------------------------------------------------------------------------------------------
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
L
L
L
L
L
R
G
V
P
E
A
N
A
-----
K
A
H
R
G
V
W
N
K
L
A
A
G
S
-----
F
E
A
R
G
K
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
----
I
E
N
K
L
P
L
G
N
A
T
Q
--
V
Q
H
L
S
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
C
D
A
L
A
S
K
H
L
A
G
A
A
I
D
V
F
P
T
E
------------
P
A
------
T
-----------
N
-----
S
D
P
F
T
S
P-
L
C
E
F
D
-
N
V
L
L
T
P
---
H
I
G
G
S
T
Q
E
A
Q
E
N
I
G
L
E
V
A
G
K
L
I
K
Y
S
D
N
G
S
T
L
S
A
V
N
F
P
E
V
---------------------------------------------------------------------------------------------------------------------------
S
L
P
L
------
H
-
G
G
R
R
L
M
H
I
H
E
N
R
P
G
V
L
-------
T
A
L
N
K
I
F
-
A
E
Q
G
V
N
I
A
A
Q
Y
L
--
Q
T
S
A
Q
M
G
Y
V
V
I
D
I
E
A
D
--
E
D
V
-
A
E
K
A
L
Q
A
----
M
K
A
I
P
--------
G
T
I
R
A
R
L
L
---------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
82.70
29%
-93
- C2 -
2P9C
2
SERA_ECOLI
A:
[74-409]
--------------------------------------------------------------------------------------------------
E
K
L
V
A
I
G
A
F
A
I
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
L
L
L
L
L
R
G
V
P
E
A
N
A
-----
K
A
H
R
G
V
W
N
K
L
A
A
G
S
-----
F
E
A
R
G
K
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
----
I
E
N
K
L
P
L
G
N
A
T
Q
--
V
Q
H
L
S
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
A
D
A
L
A
S
K
H
L
A
G
A
A
I
D
V
F
P
T
E
------------
P
A
------
T
-----------
N
-----
S
D
P
F
T
S
P-
L
A
E
F
D
-
N
V
L
L
T
P
---
H
I
G
G
S
T
Q
E
A
Q
E
N
I
G
L
E
V
A
G
K
L
I
K
Y
S
D
N
G
S
T
L
S
A
V
N
F
P
E
V
---------------------------------------------------------------------------------------------------------------------------
S
L
P
L
------
H
-
V
G
R
R
L
M
H
I
H
E
N
R
P
G
V
L
-------
T
A
L
N
K
I
F
-
A
E
Q
G
V
N
I
A
A
Q
Y
L
--
Q
T
S
A
Q
M
G
Y
V
V
I
D
I
E
A
D
--
E
D
V
-
A
E
K
A
L
Q
A
----
M
K
A
I
P
--------
G
T
I
R
A
R
L
L
---------------------------------------------------------------------------------------------------------------
63
Fugue
82.53
27%
-75
- C2 -
1YGY
1
SERA_MYCTU
A:
[3-529]
S
L
P
V
V
L
I
ADKLA
P
S
T
V
A
A
L
G
D
Q
V
E
V
R
W
V
D
G
P
D
R
D
K
-----
L
L
A
--------
A
-----------
V
----
P
-
E
A
D
A
L
L
V
R
S
ATT
V
-
D
-
A
E
V
--
L
A
A
---
A
P
K
L
K
I
V
A
R
A
G
V
G
L
D
N
V
D
V
D
A
A
T
A
R
G
V
L
V
V
N
A
P
T
S
N
I
H
S
A
A
E
H
A
L
A
L
L
L
A
A
S
R
----------
Q
I
P
A
A
D
A
S
L
R
E
H
T
W
K
R
S
S
F
S
G
T
E
I
F
G
K
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
A
F
G
A
Y
V
V
A
Y
D
P
Y
V
S
P
A
R
A
A
Q
L
G
I
E
L
L
----
S
L
D
D
L
L
A
R
A
D
F
I
S
V
H
L
P
K
T
P
E
T
A
G
L
I
D
K
E
A
L
A
K
T
K
P
G
V
I
I
V
N
A
A
R
G
G
L
V
D
E
A
A
L
A
D
A
I
T
G
G
H
V
R
-----
A
A
G
L
D
------------
V
F
------
A
-----------
T
-----
E
PCTDSP-
L
F
E
L
A
-
Q
V
V
V
T
P
---
H
L
G
A
S
T
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
R
L
A
L
A
G
E
F
V
P
D
A
V
N
V
G
G
G
---------------------------------------------------------------------------------------------------------------------------
V
V
N
E
------
E
-
V
A
P
W
L
D
L
V
R
K
L
G
V
L
A
G
V
L
SDELP
V
S
L
S
V
Q
V
R
G
E
L
A
A
E
E
V
E
V
L
R
--
L
S
A
L
R
G
L
F
S
A
V
I
E
D
A
V
--
T
F
V
N
A
P
A
L
A
A
E
RG
V
T
A
E
I
C
K
A
SESPNHR
S
V
V
D
V
R
A
V
G
A
D
G
S
V
V
T
V
S
G
T
L
Y
G
PQLSQKIVQING
R
H
F
D
L
R
AQ
G
I
N
L
I
I
H
Y
V
DRPG
A
L
G
K
I
G
T
L
L
G
T
A
GVNIQ
A
A
Q
L
S
E
D
AEGP
G
A
T
I
L
L
R
L
D
Q
D
V
P
D
D
V
R
T
A
I
A
A
A
VDAY
K
L
E
V
V
D
LS
59
HHSearch
82.20
32%
-98
- C2 -
1WWK
1
?
A:
[4-307]
-------------
M
K
V
L
V
A
A
P
L
H
E
K
A
I
Q
V
L
K
D
A
G
L
-----
E
V
I
--------
Y
E
E
YPD
E
D
----
R
L
V
E
L
V
K
D
V
E
A
I
I
V
R
S
---
K
P
K
-
V
T
R
--
R
V
I
E
S
-
A
P
K
L
K
V
I
A
R
A
G
V
G
L
D
N
I
D
V
E
A
A
K
E
K
G
I
E
V
V
N
A
P
A
A
S
S
R
S
V
A
E
L
A
V
G
L
M
F
S
V
A
R
K
I
A
F
A
D
R
K
M
R
E
G
----------
V
W
A
K
K
E
A
M
G
I
E
L
E
G
K
T
I
G
I
I
G
F
G
R
I
G
Y
Q
V
A
K
I
A
N
A
L
G
M
N
I
L
L
Y
D
P
Y
P
N
E
E
R
A
K
--
E
V
N
G
K
--
F
V
D
L
E
T
L
L
K
E
S
D
V
V
T
I
H
V
P
L
V
E
S
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
T
S
R
G
P
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
-----
G
A
G
L
D
------------
V
F
------
E
EEPLPKD----
H
-----
P
-------
L
T
K
F
D
-
N
V
V
L
T
P
---
H
I
G
A
S
T
V
E
A
Q
E
R
A
G
V
E
V
A
E
K
V
V
K
I
L
K
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
81.57
29%
-89
- C2 -
1PSD
2
SERA_ECOLI
A:
[84-408]
-------------------------------------------------------------------------------------------------------------
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
L
L
L
L
L
R
G
V
P
E
A
N
A
-----
K
A
H
R
G
V
W
N
K
L
A
A
G
S
-----
F
E
A
R
G
K
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
----
I
E
N
K
L
P
L
G
N
A
T
Q
--
V
Q
H
L
S
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
C
D
A
L
A
S
K
H
L
A
G
A
A
I
D
V
F
P
T
E
------------
P
A
------
T
-----------
N
-----
S
D
P
F
T
S
P-
L
C
E
F
D
-
N
V
L
L
T
P
---
H
I
G
G
S
T
Q
E
A
Q
E
N
I
G
L
E
V
A
G
K
L
I
K
Y
S
D
N
G
S
T
L
S
A
V
N
F
P
E
V
---------------------------------------------------------------------------------------------------------------------------
S
L
P
L
------
H
-
G
G
R
R
L
M
H
I
H
E
N
R
P
G
V
L
-------
T
A
L
N
K
I
F
-
A
E
Q
G
V
N
I
A
A
Q
Y
L
--
Q
T
S
A
Q
M
G
Y
V
V
I
D
I
E
A
D
--
E
D
V
-
A
E
K
A
L
Q
A
----
M
K
A
I
P
--------
G
T
I
R
A
R
L
L
---------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
81.49
28%
-96
- C2 -
1SC6
1
SERA_ECOLI
A:
[68-403]
--------------------------------------------------------------------------------------------------
E
K
L
V
A
I
G
A
F
A
I
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
L
L
L
L
L
R
G
V
P
E
A
N
A
K
-----
A
H
R
G
V
G
N
-----
S
-----
F
E
A
R
G
K
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
----
I
E
N
K
L
P
L
G
N
A
T
Q
--
V
Q
H
L
S
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
A
D
A
L
A
S
K
H
L
A
G
A
A
I
D
V
-------------------------------------------DPFTSP-
L
A
E
F
D
-
N
V
L
L
T
P
---
H
I
G
G
S
T
Q
E
A
Q
E
N
I
G
L
E
V
A
G
K
L
I
K
Y
S
D
N
G
S
T
L
S
A
V
N
F
P
E
V
---------------------------------------------------------------------------------------------------------------------------
S
L
P
L
------
H
-
G
G
R
R
L
M
H
I
H
E
N
R
P
G
V
L
-------
T
A
L
N
K
I
F
-
A
E
Q
G
V
N
I
A
A
Q
Y
L
--
Q
T
S
A
Q
M
G
Y
V
V
I
D
I
E
A
D
--
E
D
V
-
A
E
K
A
L
Q
A
----
M
K
A
I
P
--------
G
T
I
R
A
R
L
L
---------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
81.37
29%
-90
- C2 -
2P9E
5
SERA_ECOLI
A:
[74-409]
--------------------------------------------------------------------------------------------------
E
K
L
V
A
I
G
A
F
A
I
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
L
L
L
L
L
R
G
V
P
E
A
N
A
-----
K
A
H
R
G
V
W
N
K
L
A
A
G
S
-----
F
E
A
R
G
K
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
----
I
E
N
K
L
P
L
G
N
A
T
Q
--
V
Q
H
L
S
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
A
D
A
L
A
S
K
H
L
A
G
A
A
I
D
V
F
P
T
E
------------
P
A
------
T
-----------
N
-----
S
D
P
F
T
S
P-
L
A
E
F
D
-
N
V
L
L
T
P
---
H
I
G
G
S
T
Q
E
A
Q
E
N
I
G
L
E
V
A
G
K
L
I
K
Y
S
D
N
G
S
T
L
S
A
V
N
F
P
E
V
---------------------------------------------------------------------------------------------------------------------------
S
L
P
L
------
H
-
V
G
R
R
L
M
H
I
H
E
N
R
P
G
V
L
-------
T
A
L
N
K
I
F
-
A
E
Q
G
V
N
I
A
A
Q
Y
L
--
Q
T
S
A
Q
M
G
Y
V
V
I
D
I
E
A
D
--
E
D
V
-
A
E
K
A
L
Q
A
----
M
K
A
I
P
--------
G
T
I
R
A
R
L
L
---------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
80.90
29%
-90
- C2 -
2PA3
2
SERA_ECOLI
A:
[74-409]
--------------------------------------------------------------------------------------------------
E
K
L
V
A
I
G
A
F
A
I
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
L
L
L
L
L
R
G
V
P
E
A
N
A
-----
K
A
H
R
G
V
W
N
K
L
A
A
G
S
-----
F
E
A
R
G
K
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
----
I
E
N
K
L
P
L
G
N
A
T
Q
--
V
Q
H
L
S
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
A
D
A
L
A
S
K
H
L
A
G
A
A
I
D
V
F
P
T
E
------------
P
A
------
T
-----------
N
-----
S
D
P
F
T
S
P-
L
A
E
F
D
-
N
V
L
L
T
P
---
H
I
G
G
S
T
Q
E
A
Q
E
N
I
G
L
E
V
A
G
K
L
I
K
Y
S
D
N
G
S
T
L
S
A
V
N
F
P
E
V
---------------------------------------------------------------------------------------------------------------------------
S
L
P
L
------
H
-
V
G
R
R
L
M
H
I
H
E
N
R
P
G
V
L
-------
T
A
L
N
K
I
F
-
A
E
Q
G
V
N
I
A
A
Q
Y
L
--
Q
T
S
A
Q
M
G
Y
V
V
I
D
I
E
A
D
--
E
D
V
-
A
E
K
A
L
Q
A
----
M
K
A
I
P
--------
G
T
I
R
A
R
L
L
---------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
80.81
29%
-90
- C2 -
2P9G
2
SERA_ECOLI
A:
[74-409]
--------------------------------------------------------------------------------------------------
E
K
L
V
A
I
G
A
F
A
I
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
L
L
L
L
L
R
G
V
P
E
A
N
A
-----
K
A
H
R
G
V
W
N
K
L
A
A
G
S
-----
F
E
A
R
G
K
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
----
I
E
N
K
L
P
L
G
N
A
T
Q
--
V
Q
H
L
S
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
A
D
A
L
A
S
K
H
L
A
G
A
A
I
D
V
F
P
T
E
------------
P
A
------
T
-----------
N
-----
S
D
P
F
T
S
P-
L
A
E
F
D
-
N
V
L
L
T
P
---
H
I
G
G
S
T
Q
E
A
Q
E
N
I
G
L
E
V
A
G
K
L
I
K
Y
S
D
N
G
S
T
L
S
A
V
N
F
P
E
V
---------------------------------------------------------------------------------------------------------------------------
S
L
P
L
------
H
-
V
V
R
R
L
M
H
I
H
E
N
R
P
G
V
L
-------
T
A
L
N
K
I
F
-
A
E
Q
G
V
N
I
A
A
Q
Y
L
--
Q
T
S
A
Q
M
G
Y
V
V
I
D
I
E
A
D
--
E
D
V
-
A
E
K
A
L
Q
A
----
M
K
A
I
P
--------
G
T
I
R
A
R
L
L
---------------------------------------------------------------------------------------------------------------
45
HHSearch
80.18
33%
-95
- C2 -
2G76
3
SERA_HUMAN
A:
[26-327]
------------
L
R
K
V
L
I
S
D
S
L
D
P
C
C
R
K
I
L
Q
D
G
G
L
-----
Q
V
V
--------
E
K
Q
NLS
K
E
E
L
I
A
E
----
L
Q
D
C
E
G
L
I
V
R
S
---
A
T
K
-
V
T
A
--
D
V
I
N
A
-
A
E
K
L
Q
V
V
G
R
A
G
T
G
V
D
N
V
D
L
E
A
A
T
R
K
G
I
L
V
M
N
T
P
N
G
N
S
L
S
A
A
E
L
T
C
G
M
I
M
C
L
A
R
Q
I
P
Q
A
T
A
S
M
K
D
G
----------
K
W
E
R
K
K
F
M
G
T
E
L
N
G
K
T
L
G
I
L
G
L
G
R
I
G
R
E
V
A
T
R
M
Q
S
F
G
M
K
T
I
G
Y
D
P
I
I
S
P
E
V
S
A
--
S
F
G
V
Q
--
Q
L
P
L
E
E
I
W
P
L
C
D
F
I
T
V
H
T
P
L
L
P
S
T
T
G
L
L
N
D
N
T
F
A
Q
C
K
K
G
V
R
V
V
N
C
A
R
G
G
I
V
D
E
G
A
L
L
R
A
L
Q
S
G
Q
C
A
-----
G
A
A
L
D
------------
V
F
------
T
EEPPRD-----
R
-----
A
-------
L
V
D
H
E
-
N
V
I
S
C
P
---
H
L
G
A
S
T
K
E
A
Q
S
R
C
G
E
E
I
A
V
Q
F
V
D
M
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
79.01
29%
-101
- C2 -
4NFY
1
?
A:
[23-297]
---------------------
L
E
K
A
G
H
E
V
V
M
I
E
K
Y
KK
K
E
D
V
I
E
--------
R
-----------
I
----
K
-
D
A
D
G
V
I
V
R
S
---
D
-
K
-
I
D
E
E
I
I
K
A
---
G
E
K
V
K
I
I
V
R
A
G
A
G
Y
D
N
I
D
I
E
A
C
N
Q
G
K
I
V
V
M
N
T
P
G
Q
N
R
N
G
V
A
E
L
C
I
G
M
M
I
F
G
F
R
K
-----------------------
G
F
K
E
G
K
G
R
E
L
K
D
K
T
L
G
I
C
G
C
G
Y
V
G
K
R
V
K
E
I
A
E
G
I
G
M
K
I
K
V
Y
D
P
F
I
T
T
E
N
Q
V
K
----------
K
I
E
E
L
F
E
E
C
Q
V
I
S
L
H
L
P
L
T
K
E
T
K
G
K
I
G
Y
E
L
I
K
K
L
P
Y
G
G
M
I
C
N
T
A
R
K
E
I
I
D
E
E
G
L
I
R
I
M
R
E
R
E
D
L
-----
I
Y
I
T
D
------------
V
A
PT----
S
-----------
K
-----
V
-------
F
N
N
E
F
-
K
G
R
F
F
A
T
PI
K
I
G
A
E
T
E
E
S
N
I
N
A
G
M
A
A
A
S
Q
I
C
D
F
F
T
N
G
T
V
K
F
Q
V
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
78.90
36%
-103
- C2 -
1WWK
1
?
A:
[67-306]
----------------------------------------------------------------------------------------------------
L
K
V
I
A
R
A
G
V
G
L
D
N
I
D
V
E
A
A
K
E
K
G
I
E
V
V
N
A
P
A
A
S
S
R
S
V
A
E
L
A
V
G
L
M
F
S
V
A
R
K
I
A
F
---------
A
D
R
K
M
R
E
G
V
W
A
K
K
E
A
M
-
G
I
E
L
E
G
K
T
I
G
I
I
G
F
G
R
I
G
Y
Q
V
A
K
I
A
N
A
L
G
M
N
I
L
L
Y
D
P
Y
P
N
E
E
R
A
----
K
E
V
N
G
K
F
V
D
L
E
T
L
L
K
E
S
D
V
V
T
I
H
V
P
L
V
E
S
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
T
S
R
G
P
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
-----
G
A
G
L
D
------------
V
F
------
E
-----------
E
-----
E
PLPKDHP
L
T
K
F
D
-
N
V
V
L
T
P
---
H
I
G
A
S
T
V
E
A
Q
E
R
A
G
V
E
V
A
E
K
V
V
K
I
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.71
33%
-97
- C2 -
3DDN
1
SERA_MYCTU
A:
[44-313]
-----------------------------------------------------------------------
A
D
A
L
L
V
R
S
---
A
-
T
-
T
V
D
--
A
E
V
L
A
A
A
P
K
L
K
I
V
A
R
A
G
V
G
L
D
N
V
D
V
D
A
A
T
A
R
G
V
L
V
V
N
A
P
T
S
N
I
H
S
A
A
E
H
A
L
A
L
L
L
A
A
S
R
----------
Q
I
P
A
A
D
A
S
L
R
E
H
T
W
K
R
S
S
F
S
G
T
E
I
F
G
K
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
A
F
G
A
Y
V
V
A
Y
D
P
Y
V
S
P
A
R
A
A
Q
L
G
I
E
L
----
L
S
L
D
D
L
L
A
R
A
D
F
I
S
V
H
L
P
K
T
P
E
T
A
G
L
I
D
K
E
A
L
A
K
T
K
P
G
V
I
I
V
N
A
A
R
G
G
L
V
D
E
A
A
L
A
D
A
I
T
G
G
H
V
R
-----
A
A
G
L
D
V-----------
F
A
------
T
-----------
E
PCTDS
P
-------
L
F
E
L
A
-
Q
V
V
V
T
P
---
H
L
G
A
S
T
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
R
L
A
L
A
G
E
F
V
P
D
A
V
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
78.54
36%
-102
- C2 -
1WWK
1
?
B:
[67-305]
----------------------------------------------------------------------------------------------------
L
K
V
I
A
R
A
G
V
G
L
D
N
I
D
V
E
A
A
K
E
K
G
I
E
V
V
N
A
P
A
A
S
S
R
S
V
A
E
L
A
V
G
L
M
F
S
V
A
R
K
I
A
F
---------
A
D
R
K
M
R
E
G
V
W
A
K
K
E
A
M
-
G
I
E
L
E
G
K
T
I
G
I
I
G
F
G
R
I
G
Y
Q
V
A
K
I
A
N
A
L
G
M
N
I
L
L
Y
D
P
Y
P
N
E
E
R
A
----
K
E
V
N
G
K
F
V
D
L
E
T
L
L
K
E
S
D
V
V
T
I
H
V
P
L
V
E
S
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
T
S
R
G
P
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
-----
G
A
G
L
D
------------
V
F
------
E
-----------
E
-----
E
PLPKDHP
L
T
K
F
D
-
N
V
V
L
T
P
---
H
I
G
A
S
T
V
E
A
Q
E
R
A
G
V
E
V
A
E
K
V
V
K
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
78.44
33%
-98
- C2 -
1YGY
-
SERA_MYCTU
A:
[45-314]
-----------------------------------------------------------------------
A
D
A
L
L
V
R
S
---
A
-
T
-
T
V
D
--
A
E
V
L
A
A
A
P
K
L
K
I
V
A
R
A
G
V
G
L
D
N
V
D
V
D
A
A
T
A
R
G
V
L
V
V
N
A
P
T
S
N
I
H
S
A
A
E
H
A
L
A
L
L
L
A
A
S
R
----------
Q
I
P
A
A
D
A
S
L
R
E
H
T
W
K
R
S
S
F
S
G
T
E
I
F
G
K
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
A
F
G
A
Y
V
V
A
Y
D
P
Y
V
S
P
A
R
A
A
Q
L
G
I
E
L
----
L
S
L
D
D
L
L
A
R
A
D
F
I
S
V
H
L
P
K
T
P
E
T
A
G
L
I
D
K
E
A
L
A
K
T
K
P
G
V
I
I
V
N
A
A
R
G
G
L
V
D
E
A
A
L
A
D
A
I
T
G
G
H
V
R
-----
A
A
G
L
D
V-----------
F
A
------
T
-----------
E
PCTDS
P
-------
L
F
E
L
A
-
Q
V
V
V
T
P
---
H
L
G
A
S
T
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
R
L
A
L
A
G
E
F
V
P
D
A
V
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
78.19
29%
-98
- C2 -
4NJM
1
?
A:
[25-299]
---------------------
L
E
K
A
G
H
E
V
V
M
I
E
K
Y
KK
K
E
D
V
I
E
--------
R
-----------
I
----
K
-
D
A
D
G
V
I
V
R
S
---
D
-
K
-
I
D
E
E
I
I
K
A
---
G
E
K
V
K
I
I
V
R
A
G
A
G
Y
D
N
I
D
I
E
A
C
N
Q
G
K
I
V
V
M
N
T
P
G
Q
N
R
N
G
V
A
E
L
C
I
G
M
M
I
F
G
F
R
K
-----------------------
G
F
K
E
G
K
G
R
E
L
K
D
K
T
L
G
I
C
G
C
G
Y
V
G
K
R
V
K
E
I
A
E
G
I
G
M
K
I
K
V
Y
D
P
F
I
T
T
E
N
Q
V
K
----------
K
I
E
E
L
F
E
E
C
Q
V
I
S
L
H
L
P
L
T
K
E
T
K
G
K
I
G
Y
E
L
I
K
K
L
P
Y
G
G
M
I
C
N
T
A
R
K
E
I
I
D
E
E
G
L
I
R
I
M
R
E
R
E
D
L
-----
I
Y
I
T
D
------------
V
A
P-----
T
-----------
S
-----
K
-------
V
F
N
N
E
F
K
G
R
F
F
A
T
PI
K
I
G
A
E
T
E
E
S
N
I
N
A
G
M
A
A
A
S
Q
I
C
D
F
F
T
N
G
T
V
K
F
Q
V
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
76.88
33%
-89
- C2 -
3DDN
1
SERA_MYCTU
B:
[44-315]
-----------------------------------------------------------------------
A
D
A
L
L
V
R
S
---
A
-
T
-
T
V
D
--
A
E
V
L
A
A
A
P
K
L
K
I
V
A
R
A
G
V
G
L
D
N
V
D
V
D
A
A
T
A
R
G
V
L
V
V
N
A
P
T
S
N
I
H
S
A
A
E
H
A
L
A
L
L
L
A
A
S
R
----------
Q
I
P
A
A
D
A
S
L
R
E
H
T
W
K
R
S
S
F
S
G
T
E
I
F
G
K
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
A
F
G
A
Y
V
V
A
Y
D
P
Y
V
S
P
A
R
A
A
Q
L
G
I
E
L
----
L
S
L
D
D
L
L
A
R
A
D
F
I
S
V
H
L
P
K
T
P
E
T
A
G
L
I
D
K
E
A
L
A
K
T
K
P
G
V
I
I
V
N
A
A
R
G
G
L
V
D
E
A
A
L
A
D
A
I
T
G
G
H
V
R
-----
A
A
G
L
D
V-----------
F
A
------
T
-----------
E
PCTDS
P
-------
L
F
E
L
A
-
Q
V
V
V
T
P
---
H
L
G
A
S
T
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
R
L
A
L
A
G
E
F
V
P
D
A
V
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
76.67
35%
-99
- C2 -
2G76
3
SERA_HUMAN
B:
[66-317]
--------------------------------------------------------------------
Q
-
D
C
E
G
L
I
V
R
S
---
A
-
T
-
K
V
T
--
A
D
V
I
N
A
A
E
K
L
Q
V
V
G
R
A
G
T
G
V
D
N
V
D
L
E
A
A
T
R
K
G
I
L
V
M
N
T
P
N
G
N
S
L
S
A
A
E
L
T
C
G
M
I
M
C
L
A
R
Q
I
P
Q
A
T
A
S
M
K
D
G
K
W
E
----------
R
K
K
F
M
G
T
E
L
N
G
K
T
L
G
I
L
G
L
G
R
I
G
R
E
V
A
T
R
M
Q
S
F
G
M
K
T
I
G
Y
D
P
I
I
S
P
E
V
S
A
S
F
G
V
Q
----
Q
L
P
L
E
E
I
W
P
L
C
D
F
I
T
V
H
T
P
L
L
P
S
T
T
G
L
L
N
D
N
T
F
A
Q
C
K
K
G
V
R
V
V
N
C
A
R
G
G
I
V
D
E
G
A
L
L
R
A
L
Q
S
G
Q
C
A
-----
G
A
A
L
D
------------
V
F
------
T
-----------
E
-----
E
PPRDRA-
L
V
D
H
E
-
N
V
I
S
C
P
---
H
L
G
A
S
T
K
E
A
Q
S
R
C
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
75.05
35%
-96
- C2 -
2G76
3
SERA_HUMAN
A:
[66-317]
--------------------------------------------------------------------
Q
-
D
C
E
G
L
I
V
R
S
---
A
-
T
-
K
V
T
--
A
D
V
I
N
A
A
E
K
L
Q
V
V
G
R
A
G
T
G
V
D
N
V
D
L
E
A
A
T
R
K
G
I
L
V
M
N
T
P
N
G
N
S
L
S
A
A
E
L
T
C
G
M
I
M
C
L
A
R
Q
I
P
Q
A
T
A
S
M
K
D
G
K
W
E
----------
R
K
K
F
M
G
T
E
L
N
G
K
T
L
G
I
L
G
L
G
R
I
G
R
E
V
A
T
R
M
Q
S
F
G
M
K
T
I
G
Y
D
P
I
I
S
P
E
V
S
A
S
F
G
V
Q
----
Q
L
P
L
E
E
I
W
P
L
C
D
F
I
T
V
H
T
P
L
L
P
S
T
T
G
L
L
N
D
N
T
F
A
Q
C
K
K
G
V
R
V
V
N
C
A
R
G
G
I
V
D
E
G
A
L
L
R
A
L
Q
S
G
Q
C
A
-----
G
A
A
L
D
------------
V
F
------
T
-----------
E
-----
E
PPRDRA-
L
V
D
H
E
-
N
V
I
S
C
P
---
H
L
G
A
S
T
K
E
A
Q
S
R
C
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------