@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu28160: (2016-07-14 )
MIDTAMARLNEGTIVIYALSVLFYFIDFLQHNRKAGKMAFWLLSIVWTLQTVYLAYFMWVTGRFPVLNVTEALYFYAWVLVTLSLVLTKLLRVDFIVFFTNVIGFSMIAIHTFSPTEQQSAAFSGQLVSELLVIHITMAILSYGAFSLSFVFSVLYMFQYHLLKKKKWGKWLLRIEDLSKLDYMAYVLNVIGVPMLLLSLILGVIWAYVSLETLYWFDAKVLGSFVVLLLYSYYLYIRLIKELQGKVAALWNTACFLVLMINYFLLGSLSQFHWFS
Atome Classification :
(20 SA)
-----------------------.........10----..-----------------------.......20.-----...------...----.30....-------------...---------.-40........50........60--.......-------..70....-....80---.------------........90----..-.---.....-----------.100----.....--...110--------.------------..--..-------..----------120..----.....130.....--..140-------...---------------...----.--.----------.150..--------......160..--.....170...----....180.......------190.....--..--200---.....----..210---.-..-----..----------.----.--..220.......230.---......240.......-250..--.....260-----.--.......270-......-------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------MI
D
T
A
M
A
RLN-----EG-----------------------
T
I
V
I
Y
A
L
S
V
L
-----
F
Y
F
------
I
D
F
----
L
QHNRKA-------------
G
K
M
---------
A
-
F
W
L
L
S
I
V
W
T
L
Q
T
V
Y
L
A
Y
F
M
W
V---TGRFP
V
L
-------
N
V
T
E
A
L
Y
F
-
Y
A
W
V
L
----
V
------------
T
L
S
L
V
L
T
K
L
-----
L
R
-
V
---
D
F
I
V
F
-----------
F
T
N
-----VIG
F
S
--
M
I
A
I
H
T--------F------------SP--
T
E
-------
Q
Q
----------
S
A
AF
S
----
G
Q
L
V
S
E
L
L
V
I
H
I
T
--
M
A
I
---------
L
S
Y
---------------
G
A
F
----
S
--
L
----------
S
F
V
-
F
S
--------
V
L
Y
M
F
Q
Y
H
L
L
K
--
K
KKW
G
K
W
L
L
R
I
----
E
D
L
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K
L
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Y
M
A
Y
V
L
N
------VI
G
V
P
M
L
L
--
L
S
--
L
I
L
---
G
V
I
W
A
----
Y
V
S
-----
L
-
E
T
-----
L
Y
----------
W
----
F
--
D
A
K
V
L
G
S
F
V
V
L
L
L
Y
S
Y
---
Y
L
Y
I
R
L
I
K
E
L
Q
G
K
V
A
A
-
L
W
N
T
A
--
C
F
L
V
L
M
-
I
-----
N
--
Y
F
L
L
GS
L
S
---
Q
FHWFS-------------------------------------------------------------------------------------
24
Fugue
66.84
22%
-114
- C3 -
4QT9
2
?
A:
[19-432]
--------------LS
D
D
A
L
M
D
T
V
Q
R
R
T
F
L
Y
F
W
-----
E
G
AEPNSGLAPERYHVDGVYPQNDA
N
V
V
T
S
G
G
S
G
F
G
I
M
A
I
L
A
G
------
I
D
R
----
G
Y
V
T
R
E
E
-------------
G
L
A
---------
R
M
E
R
I
V
S
F
L
E
K
A
D
R
F
H
G
A
Y
P
H
W
W
YGD
T
G
K
V
K
P
F
GQKDNGG
D
L
V
E
T
A
F
L
M
Q
G
L
L
A
----
V
H
Q
Y
Y
A
NGN
D
K
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K
A
I
A
Q
R
I
D
R
L
-----
W
R
E
V
---
D
W
D
W
Y
RKGGQNVLYWH
W
S
P
-----
T
Y
G
W
E
M-
D
F
P
I
H
G
--------
Y
NEC
M
I
M
Y
I
L
A
A
A
S
P
--
T
H
GVP
A
A
V
Y
H
D
----------
G
W
A
Q
N
----
G
A
I
V
S
P
H
K
V
E
G
I
E
--
L
H
L
RYQGTEAGP
L
F
W
---------------
A
Q
Y
----
S
--
F
LGLDPVGLKD
E
Y
C
-
P
S
Y
F
H
E
M
R
N
L
T
L
V
N
R
A
Y
C
I
R
N
--
P
K
H
Y
K
G
F
G
P
D
C
W
G
L
T
A
S
Y
S
V
D
G
Y
A
A
H
S
P
N
EQDDKG
V
I
S
-
P
T
A
A
--
L
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--
S
I
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---
Y
T
P
E
Y
----
S
L
Q
-----
V
M
R
H
-----
L
Y
----------
N
M
---
G
--
D
-
K
V
F
G
P
F
G
F
Y
D
A
F
S
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TDN
W
Y
P
Q
R
Y
L
A
I
D
Q
G
P
I
A
V
M
I
E
N
Y
R
TG
L
L
W
K
L
F
M
S
-----
H
--
P
D
V
Q
A
G
L
T
---
K
L
G
F
N
T
N------------------------------------------------------------------------------------
21
Fugue
66.00
14%
-107
* C3 *
3TUR
6
LDT2_MYCTO
A:
[29-286]
-----------------------
H
L
T
M
P
Y
V
M
P
G
-----
D
G
-----------------------
E
V
V
G
V
G
E
P
V
A
-----
I
R
F
------
D
E
N
----
I
A
D
R
G
A
A
-------------
E
K
A
----------------
I
K
I
T
T
N
P
P
V
E
G
A
F
Y
W
L
---
N
N
R
--
E
V
-------
R
W
R
P
E
H
F
W
-
K
P
G
T
A
----
V
------------
D
V
A
V
N
T
Y
G
V
DLGEG
M
F
-
G
---
E
D
N
V
Q
-----------
T
H
F
-----
T
I
G
D
E
--
V
I
A
T
A
D
---------------------
D
N
--
T
K
-------
I
L
----------
T
V
R
V
N
----
G
E
V
V
K
S
M
P
T
---
S
--
M
G
K
---------
D
S
T
---------------
P
T
A
----
N
--
G
----------
I
Y
I
-----------
V
G
S
R
Y
K
H
I
I
M
D
--
S
S
T
Y
G
------------
V
P
V
N
S
P
N
G
Y
R
T
D
------
V
D
W
A
T
Q
I
S
--
Y
S
GV
F
V
H
---
S
A
P
W
S
----
V
G
A
-----
Q
-
G
H
-------------------------
T
N
T
S
H
G
C
L
N
V
S
P
S
N
A
Q
---
W
F
Y
D
H
V
K
R
---
G
D
I
V
E
-
V
V
N
T
V
--
G
G
T
L
P
G
-
I
-----
D
--
G
L
G
D
W
N
I
P
---
W
D
Q
W
R
A
GNAK---------------------------------------------------------------------------------
23
Fugue
63.42
18%
-82
* C4 *
4V12
2
?
A:
[7-343]
-----------------------
D
T
S
T
L
E
S
R
V
G
H
Y
Y
Q
M
E
D
-----------------------
T
Y
L
V
-
G
R
E
K
V
-----
R
E
F
------
A
R
A
----
V
Q
D
Y
H
P
A
HWN
L
A
T
A
A
D
L
GHP
G
L
I
---------
A
-
P
L
T
F
T
S
A
P
A
M
A
C
N
Q
R
M
F
E
S
V
V
---
V
G
Y
D
M
Y
L
-------
Q
T
E
E
V
F
E
Q
-
H
R
P
I
V
EG
D
E
L
------------
S
I
D
I
E
L
T
S
V
-----
R
R
-
I
AGR
D
L
I
T
V
-----------
T
N
T
-----
F
T
D
T
A
--
G
E
V
V
H
T
--------
L
------------
H
T
--
T
V
-------
V
G
I
T
AEDVDPA
I
R
P
A
V
Q
----
G
V
M
M
H
G
I
N
M
L
G
V
E
--
E
T
N
---------
A
P
Y
E
K
T
V
R
P
EGELRIAQG
G
A
T
RTPT
S
--
L
----------
N
F
D
D
L
K
--------
V
G
E
E
L
P
V
H
T
A
R
L
S
R
G
D
L
V
N
Y
A
G
V
A
----
G
D
A
N
P
L
H
W
D
E
N
I
A
K
------
L
A
G
Q
P
D
V
I
AH
G
M
--
L
T
M
---
G
L
G
A
G
----
F
V
S
-----
S
-
W
S
GDPGA
I
T
----------
R
----
Y
--
A
V
R
L
S
Q
P
A
V
V
P
A
E
G
T
E
---
I
E
Y
S
G
R
I
K
S
L
D
P
E
T
-----
R
T
G
--
V
V
I
V
A
A
-
K
-----
S
GG
R
K
I
F
G
L
A
T
---
A
T
I
R
F
S
-------------------------------------------------------------------------------------
19
Fugue
61.16
16%
-110
- C2 -
2W18
5
A:
[24-356]
-----------------------
N
L
Q
L
V
S
E
L
K
N
-----
P
S
-----------------------
G
S
C
S
V
D
V
S
A
M
-----
F
W
E
------
K
E
P
----
C
I
I
T
A
C
E
-------------
D
V
V
---------
S
-
L
W
K
A
L
D
A
W
Q
W
E
K
L
Y
T
W
H
F
-------
A
E
V
P
V
L
-------
Q
I
V
P
V
P
D
V
-
Y
N
L
V
C
----
V
------------
A
L
G
N
L
E
I
R
E
-----
I
R
-
A
L
F
C
E
K
Q
V
L
-----------
L
K
S
GNIK
A
V
L
G
L
T
KR
R
L
V
S
S
S
--------
G
------------
T
L
--
S
D
-------
Q
Q
----------
V
E
V
M
T
F
A
ED
G
G
G
K
E
N
Q
F
L
M
P
P
E
--
E
T
I
---------
L
T
F
---------------
A
E
V
----
Q
GM
Q
----------
E
A
L
-
L
G
--------
T
T
I
M
N
N
I
V
I
W
N
--
L
K
T
-
G
Q
L
L
K
K
M
----
H
-
I
D
D
A
S
V
C
H
K
A
Y
S
------
E
M
G
L
L
F
I
V
--
L
S
--
P
V
F
---
Q
L
I
V
I
NPKT
T
L
S
-----
V
-
G
V
-----
M
L
Y
C
L
P
P
G
Q
A
G
R
F
----
L
--
E
G
D
V
K
D
H
C
A
A
A
I
L
T
S
G
---
T
I
A
I
W
D
L
--
L
L
G
Q
C
T
A
-
L
L
P
P
V
--
Q
H
W
S
F
V
-
K
W
S
GTD
S
--
H
L
L
A
G
Q
K
D
G
N
I
F
V
Y
H
Y
S
-------------------------------------------------------------------------------------
25
Fugue
58.89
12%
-52
- C4 -
4XB6
3
PHNJ_ECOLI
D:
[2-278]
---------------------AN
L
S
G
Y
N
F
A
Y
L
D
-----
E
Q
-----------------------
T
K
R
M
I
R
R
A
I
L
-----
K
A
V
A
I
PGY
Q
V
P
F
G
G
R
E
M
P
M
P
Y
G
W
-------------
G
T
G
---------
G
-
I
Q
L
T
A
S
V
I
G
E
S
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V
L
K
V
I
D
Q
G
A
---
D
D
T
T
N
A
V
-------
S
I
R
N
F
F
K
R
-
V
T
G
V
N
----
T
------------
T
E
R
T
D
D
A
T
V
-----
I
Q
-
T
---
R
H
R
I
P
-----------
E
T
P
-----
L
T
E
D
Q
--
I
I
I
F
Q
V
PIPEPLRF
I
------------
E
P
--
R
E
-------
T
E
----------
T
R
T
M
H
----
A
L
E
E
Y
G
V
M
Q
V
K
L
Y
--
E
D
I
---------
A
R
F
---------------
G
H
I
----
A
--
T
----------
T
Y
A
-
Y
P
--------
V
K
V
N
G
R
Y
V
M
D
P
--
S
P
------
I
P
K
----
F
D
N
P
K
M
D
M
M
P
-
A
L
Q
------
L
F
G
A
G
R
-----
E
--
K
R
I
---
Y
A
V
P
P
----
F
T
R
-----
V
-
E
S
-----
L
D
----------
F
DD
H
P
F
--
T
V
Q
Q
W
D
E
P
C
A
I
C
G
S
T
H
---
S
Y
L
D
E
V
V
L
D
D
A
G
N
------------
R
M
F
V
C
-
S
-----
D
--
T
D
Y
C
R
Q
Q
S
---
E
A
-----------------------------------------------------------------------------------------
18
Fugue
50.00
14%
-133
- C5 -
5AYN
10
?
A:
[7-426]
LR
I
E
T
Q
L
L
L
G
R
L
L
T
R
S
G
D
Q
A
W
D
F
V
V
P
F
A
L
L
V
I
F
-----
P
G
-----------------------
K
L
Q
V
A
A
F
Y
Y
L
-----
I
V
K
------
I
G
T
----
F
L
L
T
P
S
S
-------------
G
K
W
I
D
T
H
P
R
I
Q
V
V
-
K
W
G
V
W
L
Q
F
F
A
I
L
A
G
M
V
F
F
G
M
L
---
D
G
L
V
R
A
G
-------
G
R
E
S
W
L
L
S
-
V
L
F
I
A
----
L
------------
A
L
S
G
V
M
A
S
L
-----
G
S
-
Q
---
I
T
D
I
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-----------
V
G
N
-----
D
L
A
P
S
--
L
V
A
P
E
K
--------
L
------------
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H
F
N
S
W
-------
L
R
----------
R
I
D
L
A
----
T
E
V
G
A
P
I
L
A
G
A
L
F
PL
A
G
L
---------
F
L
I
---------------
G
L
W
----
N
--
L
----------
V
S
F
-
V
P
--------
E
Y
F
L
L
R
N
V
I
Q
R
--
S
G
L
K
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K
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E
A
----
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N
L
R
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S
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P
I
F
W
L
------
I
L
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Y
A
L
L
W
--
L
S
--
V
L
S
PHG
V
L
L
A
A
----
Y
L
K
DEMRL
P
-
E
T
-----
E
I
----------
G
----
L
--
F
R
G
L
G
A
V
F
G
L
I
S
T
V
S
F
---
P
Y
L
V
R
R
L
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L
I
S
S
S
R
W
H
-
L
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G
--
V
T
L
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A
-
V
-----
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--
A
F
A
M
G
S
T
A
---
S
V
Y
V
F
L
G
C
I
L
L
S
R
V
G
L
Y
G
F
S
N
G
E
F
E
L
R
Q
R
L
IPEGR
R
G
E
L
N
S
L
S
S
L
T
T
T
S
A
T
L
I
L
F
S
A
G
S
L
L
PQTED
F
K
Y
L
V
Y
V
S
L
A
A
V
L
L
A
N
V
V
F
I
K
W
S
SR
6
PsiBlast_PDB
39.81
31%
-112
- C6 -
1OMJ
-
?
A:
[403-453]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
K
L
-----
G
G
-
L
---
N
F
V
D
A
-----------
F
T
G
-----
H
A
G
D
A
--
I
V
S
Y
H
Q
--------
A
------------
S
N
--
A
G
-------
S
L
----------
Q
V
D
F
S
----
G
Q
G
V
A
D
F
L
V
T
T
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
39.48
31%
-100
- C6 -
1O0T
-
?
A:
[403-453]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
K
L
-----
G
G
-
L
---
N
F
V
D
A
-----------
F
T
G
-----
H
A
G
D
A
--
I
V
S
Y
H
Q
--------
A
------------
S
N
--
A
G
-------
S
L
----------
Q
V
D
F
S
----
G
Q
G
V
A
D
F
L
V
T
T
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
39.10
31%
-104
* C6 *
1H71
-
?
P:
[403-453]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
K
L
-----
G
G
-
L
---
N
F
V
D
A
-----------
F
T
G
-----
H
A
G
D
A
--
I
V
S
Y
H
Q
--------
A
------------
S
N
--
A
G
-------
S
L
----------
Q
V
D
F
S
----
G
Q
G
V
A
D
F
L
V
T
T
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
39.02
31%
-108
- C6 -
1O0Q
-
?
A:
[403-453]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
K
L
-----
G
G
-
L
---
N
F
V
D
A
-----------
F
T
G
-----
H
A
G
D
A
--
I
V
S
Y
H
Q
--------
A
------------
S
N
--
A
G
-------
S
L
----------
Q
V
D
F
S
----
G
Q
G
V
A
D
F
L
V
T
T
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
38.79
31%
-106
- C6 -
1G9K
-
?
A:
[403-453]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
K
L
-----
G
G
-
L
---
N
F
V
D
A
-----------
F
T
G
-----
H
A
G
D
A
--
I
V
S
Y
H
Q
--------
A
------------
S
N
--
A
G
-------
S
L
----------
Q
V
D
F
S
----
G
Q
G
V
A
D
F
L
V
T
T
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
38.72
31%
-100
- C6 -
1OM7
-
?
A:
[403-453]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
K
L
-----
G
G
-
L
---
N
F
V
D
A
-----------
F
T
G
-----
H
A
G
D
A
--
I
V
S
Y
H
Q
--------
A
------------
S
N
--
A
G
-------
S
L
----------
Q
V
D
F
S
----
G
Q
G
V
A
D
F
L
V
T
T
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
38.66
31%
-108
- C6 -
1OM6
-
?
A:
[403-453]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
K
L
-----
G
G
-
L
---
N
F
V
D
A
-----------
F
T
G
-----
H
A
G
D
A
--
I
V
S
Y
H
Q
--------
A
------------
S
N
--
A
G
-------
S
L
----------
Q
V
D
F
S
----
G
Q
G
V
A
D
F
L
V
T
T
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
30.37
31%
-266
- C5 -
2L5B
-
A:
[8-26]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
----------
W
P
---
W
L
C
A
A
A
Q
V
A
A
L
A
A
W
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
28.04
50%
-
- C1 -
1C4E
-
GUR_GYMSY
A:
[28-33]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
----
W
--
D
H
K
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
26.00
25%
-308
- C5 -
2MFR
-
A:
[18-45]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
I
--
I
G
P
---------
L
I
----------------
F
V
F
----
L
--
F
----------
S
V
V
-
I
G
--------
S
I
Y
L
F
L
R
K
R
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
24.08
13%
-23
- C5 -
2F3Y
-
B:
[2-17]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Y
A
T
---
F
L
I
Q
E
Y
F
R
K
F
K
K
----------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
22.18
11%
-19
- C5 -
2BE6
-
CAC1C_HUMAN
D:
[11-28]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Y
A
T
---
F
L
I
Q
E
Y
F
R
K
F
K
K
R
K
--------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
20.93
13%
-264
- C5 -
5DJQ
-
?
N:
[11-29]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
T
---------------
V
G
L
----
M
--
V
----------
A
F
L
-
A
G
--------
F
G
Y
F
I
W
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
20.49
19%
34
- C5 -
3QBG
1
BACH_NATPH
A:
[30-60]
------------------------
N
D
P
L
L
A
S
S
L
-----
Y
I
-----------------------
N
I
A
L
A
G
L
S
I
L
-----
L
F
V
------
F
M
T
----
R
G
L
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------