@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu30240: (2016-07-19 )
MMQEETFYSVRMRASMNGSHEDGGKHISGGERLIPFHEMKHTVNALLEKGLSHSRGKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGVSRDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDANFEKWALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVAGKKMGYQRITAMKEYGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWEEDHDS
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.......--..10--.......-----..20.....--...30.-----.----------.----------...-------------..40...--.....50-------.----.....--...--60.-------------....---------.--------..70----.---------..-----.---...--------..---------80--------...----.....90---.........100-------.....------..-----.-110-----..------------.....---120---.........130.-------.-.-----------------------....140--.----........-150.......160----.......---.-----------------------170---------....---.....180-....-------..-----.--------.-.190--------....--------.---..200---....-----------------..-.-.210--.--------...--..-.220--------........230---------..--..----.---..240...---..--..250.......---------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMQEE
T
F
--
Y
S
V
---
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M
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A
SMN-----GSHEDGGKH--ISGG
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KG--------L----SHSRG--KPD--
F
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-------------
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K-----T---IQP--------LP---------VH--------TNE----VSC
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------------QIPEW---S-----DV
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IHTG-------K-R-----------------------M
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DLE---KQ--
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WEEDHDS---------------------------
24
Fugue
63.39
13%
34
- C8 -
1FOB
-
GANA_ASPAC
A:
[1-334]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALTYRGADISS
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---------------------------
27
Fugue
58.00
12%
14
* C8 *
1QFE
1
AROD_SALTI
A:
[1-252]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
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-----------------------------
21
Fugue
55.48
19%
-19
* C7 *
3PYW
1
SLAP1_BACAN
A:
[3-180]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
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K
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G
T
---------------------------
22
Fugue
55.10
17%
26
- C2 -
4M5D
14
UTP22_YEAST
A:
[81-1237]
T
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A
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------------------------------
19
Fugue
54.25
14%
35
- C8 -
1TV8
5
MOAA_STAA8
A:
[3-329]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E
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R
Q---------
28
Fugue
50.49
19%
13
- C3 -
5AYC
3
?
A:
[1-386]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIH
E
K
Y
T
E
M
R
N
E
Q
E
A
L
L
--
S
R
K
---
N
T
K
T
S
F
Y
-----
N
G
I
Y
D
R
Y
E
H
--
P
V
L
T
R
E
-----
H
----------
I
----------
P
L
H
WRYDLNKETNPFF
Q
E
R
L
G
I
N
--
A
V
F
N
A
G
--------
A
----
I
K
L
-
N
--
D
R
Y
--
C
L
V
-------------
A
R
V
E
---------
G
NDR
K
S
F
F
A
V
A
E
-----
S
---------
D
K
GTEG
F
R
---
F
R
Q
--------
Y
P
---------
V
C
LPALTDDE
T
N
V
YD
M
R
L
T
Q
H
E
D
----
G
W
I
Y
G
V
F
C
V
E
K
S
AGTADLS
E
A
V
A
S
------
A
G
-----
I
-
A
R
T
KDLT
N
W
E
------------
R
L
P
D
L
---
V
TLRSP
Q
Q
R
N
V
T
L
L
P
E
F
V
D
G
K
Y
A
F
Y
T
R
-
P
-----------------------
M
D
G
F
I
----
E
TGSG
G
G
I
G
F
G
L
A
D
D
I
T
H
A
V
I
D
E
E
R
M
-----
T
S
I
R
R
Y
H
---
T
-----------------------
I
TES
K
N
G
A
G
A
T
P
I
K
T
E
RGW
L
N
I
A
H
G
---
V
R
N
T
-------
A
A
G
L
R
Y
V
I
--------
Y
-
C
F
V
T
--------
D
L
S
E
--------
P
---
W
K
V
I
----
A
E
P
G
-----------------
G
Y
-
L
-
I
A
P
F
--
K
--------
D
E
R
--
V
G
-
D
V
S
N
V
V
F
T
N
G
A
I
V
D
D
N
G
D
V
Y
I
Y
Y
---------
A
S
--
S
D
----
T
---
R
L
H
V
A
V
S
S
---
I
D
--
K
L
L
D
Y
A
F
N
T
P
A
D
ALR
T
A
E
C
V
K
Q
R
C
D
L
I
K
R
N
I
E
L
L-----
20
Fugue
46.55
18%
34
* C5 *
4V12
2
?
A:
[7-343]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTSTLESRVG
H
Y
Y
Q
M
E
D
T
--
Y
L
V
G
R
E
K
V
R
E
F
A
R
-----
A
V
Q
D
Y
H
P
A
H
WN
L
A
T
A
A
D
-----
L
GHPGLIAPLT
F
----------
T
S
A
-------------
P
A
M
A
C
N
Q
--
R
M
F
E
S
V
--------
V
VGYD
M
Y
L
Q
T
--
E
E
V
--
F
E
Q
HRPIVEG
D
E
L
S
I
D
I
E
L
T
---------
S
--------
V
R
R
I
AGRD
L
---------
I
T
-----
V
---
T
N
T
--------
F
T
D
TAGEVV
H
T
L
H
--------
T
T
V
----
V
G
I
T
A
E
DVDP
A
I
R
P
A
V
Q
G
V
M
M
--------
H
G
I
N
M
------
L
G
-----
V
-
E
E
T
-----
N
A
P
Y
E
K
T
V
R
P
EGEL
R
I
A
Q
G
---
G
-----
A
T
R
T
P
T
S
L
N
F
D
D
L
-------
K
-
V
-----------------------
G
E
E
L
P
----
V
----
H
T
A
R
L
S
R
G
-
D
L
--
V
N
Y
A
G
V
A
G
-----
D
A
N
P
L
H
W
---
D
-----------------------
E
-----------
N
I
A
K
---
L
A
G
Q
P
D
---
V
I
A
H
-------
G
M
-----
L
--------
T
-
M
G
L
G
A
G
F
V
S
S
--
W
S
G
D
--------
P
---
G
A
I
T
----
R
Y
A
V
-----------------
R
L
-
S
-
Q
P
A
------------
V
V
P
--
A
E
-
G
T
E
---------
I
E
Y
S
G
R
I
K
S
L
D
---------
P
E
--
T
R
----
T
---
G
V
V
I
V
A
A
K
S
GG
R
K
--
I
F
G
L
A
T
A
T
I
R
F
S
---------------------------
26
Fugue
43.82
19%
20
- C5 -
2WZP
-
?
R:
[1-375]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
E
A
N
V
Y
DN
F
N
P
---
N
Y
Y
N
I
S
D
-----
F
S
M
P
N
G
K
K
E
------
K
R
-----
G
----------
L
----------
P
I
P
-------------
K
A
R
C
Q
V
I
NY
E
L
W
E
T
G
YLYTSSAT
L
----
T
V
S
V
E
--
V
G
D
--
I
V
Q
-------------
I
L
F
P
---------
E
--------
V
V
P
-----
I
EEALGKKKK
L
N
-----
L
---
D
M
V
--------
Y
L
---------
V
T
--------
D
V
D
----
E
S
N
K
A
T
----
L
K
N
Y
F
W
A
M
I
E
S
--------
L
D
V
P
N
------
A
I
-----
T
-
K
T
T
-----
N
F
------------
A
I
I
D
Y
LID
P
-----
N
K
N
N
L
M
S
Y
G
Y
F
F
N
-------
S
-
S
-----------------------
I
F
A
G
K
ATIN
R
----
K
A
E
T
S
S
A
H
-
D
V
A
K
R
I
F
S
K
V
Q
F
-----
Q
P
T
T
T
I
Q
---
H
APSETDPRNLLFINFASRNWNRK
R
-----------
I
T
T
R
---
V
D
I
K
Q
S
---
V
T
M
D
-------
T
E
-----
T
IVERSAYN
F
-
A
V
V
F
VKNKATDD
Y
T
D
P
--------
P
---
K
M
Y
I
AKNN
G
D
V
I
DYSTYHGDGTDLPDVRT
A
K
-
T
-
L
F
Y
D
--
R
DDHGNPPE
L
S
T
--
I
K
V
E
I
S
---------
P
S
T
I
V
T
R
L
I
F
N
---------
Q
N
--
E
L
----
L
---
P
L
Y
V
N
D
L
---------
V
D
I
W
Y
E
G
K
L
Y
S
GYIADRVKTEFNDRLIFVESGDKPNVI
14
HHSearch
41.87
33%
-86
- C4 -
2OYY
2
?
A:
[6-29]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
--------
T
L
V
----
T
A
T
P
Q
E
----
G
F
D
L
A
V
K
L
S
R
---------
I
A
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
39.88
24%
15
- C4 -
4ITR
3
IBPA_HISS2
A:
[138-222]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
K
E
Q
L
K
--
T
A
I
E
D
F
--------
L
----
Q
N
S
Q
G
--
K
P
L
--
T
V
Q
-------------
M
-
I
E
---------
N
--------
L
N
H
-----
G
---------
L
R
---------------------------------------------------
P
D
E
----
G
E
--
G
R
L
L
Y
K
K
--------
E
N
L
T
K
---------------
E
N
A
-----
V
F
------------
S
S
P
E
A
---
A
-----
K
I
Q
L
A
E
T
V
D
F
------------------------------------
I
N
R
A
K
----
N
----
E
G
I
E
P
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
39.79
21%
0
- C- -
3J7A
-
?
U:
[3-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
M
Y
G
K
G
K
-----
G
----------
I
S
S
S
T
L
-----
P
----------
Y
KRKQPSWLKQ
K
P
S
-------------
E
I
E
D
A
I
I
--
K
L
A
K
K
G
--------
Q
----
T
-------
P
S
--
Q
I
G
-------------
A
T
L
R
---------
D
--------
N
Y
-----------------------
G
---
I
P
Q
-------------------
V
K
--------
S
V
T
----
G
-----------
N
K
I
L
R
I
L
R
A
--------
Q
G
I
A
T
------
T
I
-----
P
-
E
D
L
-----
Y
F
------------
L
I
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
37.17
9%
-23
- C8 -
5BVL
-
?
A:
[1-184]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
D
E
A
W
--
K
C
V
---
E
Q
L
R
R
E
G
-----
T
-----------------------------------------------------------------------------------------------------
Q
-------------
I
A
Y
R
---------
S
--------
D
D
W
-----
R
---------
D
L
-----
K
---
E
A
W
--------
A
D
---------
I
L
--------
I
V
D
----
A
T
-
D
K
D
----
E
A
W
K
Q
V
E
Q
L
R
R
--------
E
G
A
T
Q
------
I
A
-----
Y
-
R
S
D
-----
D
W
------------
R
D
L
K
E
---
A
-----
W
K
K
G
A
------
D
I
-------
L
-
I
-----------------------
V
D
A
T
D
----
K
----
D
E
A
W
K
Q
V
E
-
Q
L
R
R
E
G
A
T
Q
I
A
Y
-----
R
S
D
----------------------------------------------------------------------
D
W
-----
R
--------
D
-
L
K
E
A
--------
W
K
K
G
--------
A
---
D
I
L
I
----
V
D
A
T
-----------------
D
K
-
D
-
E
A
W
K
--
Q
--------
V
E
Q
--
L
R
-
R
E
G
---------
A
T
---
Q
I
A
Y
R
S
---------
D
D
--
W
R
----
D
---
L
K
E
A
W
K
K
G
----------
A
D
I
L
I
C
D
A
T
---------------------------
23
Fugue
35.74
12%
-26
- C7 -
3BBY
5
YFCF_ECOLI
A:
[4-212]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
A
I
T
--
L
W
S
D
A
H
--------
F
----
F
S
P
Y
V
--
L
S
A
--
W
V
A
-------------
L
Q
E
K
---------
G
--------
L
S
F
-----
H
---------
I
K
-----
T
---
I
D
R
--------
V
P
---------
L
L
--------
Q
I
D
----
D
F
E
L
S
E
----
S
S
A
I
A
E
Y
L
E
D
R
--------
F
--
A
P
------
P
T
-----
W
-
E
R
I
-----
Y
P
------------
L
D
L
E
N
---
R
-----
A
R
A
R
Q
I
Q
A
W
L
R
S
D
-------
L
M
P
-----------------------
I
R
E
E
------------------------------
R
-----
P
T
D
V
V
F
A
---
G
-----------------------
A
-----------
K
K
A
P
---
L
T
A
E
G
K
---
A
S
A
E
-------
K
L
-----
F
--------
A
M
A
E
H
L
--------
L
V
L
G
--------
Q
---
P
N
L
F
----
G
E
W
C
-----------------
I
A
-
D
-
T
D
L
A
--
L
M
-------
I
N
R
--
L
V
-
L
H
G
------------------
D
E
---------
V
P
--
E
R
----
L
---
V
D
Y
A
T
F
Q
W
---
Q
R
--
A
S
V
Q
R
F
I
A
L
S
A
K
---------------------------
2
PsiBlast_PDB
34.02
25%
90
- C4 -
3GDE
-
DNLI_ARCFU
A:
[149-251]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
T
P
L
E
----
A
R
Y
L
T
R
L
I
L
N
E
MRLGVG--
E
G
I
M
R
------
D
A
-----
I
-
A
R
A
-----
F
R
------------
A
D
P
E
----------
T
V
E
R
A
Y
M
I
T
N
D
L
G
-------
R
-
V
-----------------------
A
V
V
A
K
----
K
----
E
G
----------
E
E
G
L
R
K
M
K
I
-----
E
I
H
I
P
V
R
M
M
L
A
-----------------------
Q
-----------
V
A
E
S
---
L
E
S
A
V
R
---
E
M
R
T
-------
A
A
-----
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
33.64
24%
25
- C4 -
3N3U
1
A:
[132-216]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
K
E
Q
L
K
--
T
A
I
E
D
F
--------
L
----
Q
N
S
Q
G
--
K
P
L
--
T
V
Q
-------------
M
-
I
E
---------
N
--------
L
N
H
-----
G
---------
L
R
---------------------------------------------------
P
D
E
----
G
E
--
G
R
L
L
Y
K
K
----------------------------
E
N
A
-----
V
F
------------
S
S
P
E
A
---
A
-----
K
I
Q
L
A
E
T
V
D
F
------------------------------------
I
N
R
A
K
----
N
----
E
G
I
E
P
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
31.50
9%
-124
- C4 -
4RCK
-
?
A:
[187-218]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
--
L
T
-
K
I
A
---------
T
M
T
G
G
Q
Y
F
R
A
R
---------
N
A
--
D
E
----
L
---
A
E
I
Y
Q
T
I
D
---
A
L
-----------------------------------------
3
PsiBlast_PDB
31.15
34%
-10
- C4 -
2AZQ
1
?
A:
[20-54]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--------
L
----
D
H
A
E
G
--
K
P
R
--
F
K
Q
-------------
I
I
L
R
---------
V
--------
L
Q
D
-----
T
---------
A
R
-----
L
---
I
E
D
--------
L
E
---------
I
T
--------
E
D
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
27.78
8%
-93
- C4 -
2BMM
2
?
A:
[5-43]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
-----
V
----------
G
----------
G
E
E
-------------
T
F
T
R
L
A
R
--
R
F
Y
E
G
V
--------
A
----
A
D
P
V
L
--
R
P
M
--
Y
P
E
-------------
E
D
L
G
---------
P
--------
A
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
27.15
12%
-98
- C4 -
3ZFI
-
?
A:
[44-102]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-----
D
--------
F
-
F
R
F
Y
--------
R
S
A
D
--------
K
Q
E
K
E
K
A
R
----
I
Y
L
L
-----------------
G
V
-
L
-
D
A
T
E
-----------------------------------
G
K
S
W
C
Q
Y
---------
S
Q
--
L
Q
T
V
T
L
Q
---
E
F
V
F
E
F
F
N
---
K
L
--
P
A
A
------------------------------------
12
HHSearch
26.50
14%
30
- C4 -
4XJY
2
?
A:
[34-116]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
L
C
--------
V
V
G
P
--------
T
---
E
Y
A
-----
D
G
L
L
-----------------
R
G
M
V
Q
A
N
G
R
R
V
H
--------
A
E
R
R
A
V
D
-
N
P
D
---------
L
G
T
L
C
N
V
I
Y
L
G
---------
V
V
D
E
R
E
----
R
---
Q
Q
V
F
R
S
L
A
---
G
H
--
P
V
L
S
I
S
E
R
-------------------------------