@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0001: (2015-11-27 )
MKEESELARIKSSKAVVSKTIKEGKQGRKIPIWLMRQAGRSLPEYRRAVKDTSSFMEICYNTDLVVELTLQPVARFSMDAAIIFSDILIVADVLGCDVDFIRGVGPTIKPVKNFKELRNPQKIETKTLPILNAIRKVRDKLPEEKSLIGFAGGPWTVASYIIEGRSSKTFSKVLNLHPSSLEQIIEQITEVTISYLVKQIEFGADVIQLFDSNAGVLSGELFEECVIKPTKKIVSAIKGKFPDFPIIGFPKSAGSLYKDYCEKTGVSAVSIDYNVPIEWAKENLKIPLQGNLNPSLLAYNKMEAIKETKRIIDCFRDLPFIFNLGHGVLPNTPIENIAALVDLVKSQ
Atome Classification :
(25 SA)
.........10........20........30........40.....--...50........60........70.....-...80........90........100.....----.-.110---.---......--.120-..-....--..130.......140....-----...150.......160.------......170-..---.---...---...180.......190.......200.......210.......220.......230......----.240--..-.-----......250.......260.......270.......280..--.....290.......300...-.-...310.----..-....----320.......330.......340.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MK
E
E
S
E
L
A
R
I
KS
S
K
A
V
V
S
K
T
I
K
EGKQGRK
I
P
I
W
L
M
R
Q
AGRS
L
P
E
Y
R
--
R
A
VK
D
T
S
S
F
M
E
I
CYNT
D
L
V
V
E
L
TLQ
P
V
A
R
F-SM
D
A
A
I
I
F
S
D
I
L
I
V
A
D
V
LGC
D
V
D
F
IRGVGPT----
I
-
K
P
V
----
K
---
N
F
K
ELR--NPQ--KI-ETK
T
--
L
P
I
L
N
A
I
R
K
V
R
D
KLPEEK
S
-----
L
I
GFAG
G
P
W
T
V
A
S
Y
I
IE------GRSS
K
T
F
---
S
K
---
V
---
L
NL---
H
P
S
S
L
E
Q
I
I
E
Q
I
T
E
V
T
I
S
Y
L
V
K
Q
I
EF
G
A
D
V
I
Q
L
FDSNAGVL
S
G
E
L
F
E
E
C
VIK
P
T
K
K
I
V
S
A
I
K----GK----FP-D-----FPIIGFPK
S
A
G
S
L
Y
K
D
Y
C
E
KTG
V
S
A
V
S
I
D
YNVP
I
E
W
A
KEN
L
--
K
I
P
LQGNL
N
P
S
L
L
A
Y
N
K
M
E
A
I
-
K
-
E
T
K
R
I
I
D
----
C
F
-RD
L
P
----
F
I
F
NLGHGVLPNT
P
I
E
N
I
A
A
L
V
D
L
VKSQ
10
PsiBlast_PDB
97.67
36%
-122
- C1 -
4EXQ
-
DCUP_BURTA
A:
[27-358]
------------------------------
P
I
W
L
M
R
Q
A
G
R
Y
L
P
E
Y
N
--
A
T
R
A
R
A
G
S
F
L
G
L
A
K
H
P
D
Y
A
T
E
V
T
L
Q
P
L
E
R
F
-
P
L
D
A
A
I
L
F
S
D
I
L
T
I
P
D
A
M
G
L
G
L
D
F
----
G
P
K
----
F
A
H
P
V
----
R
T
E
A
D
V
A
K
L
A
--
V
P
D
---
I
-
G
A
T
L
--
G
Y
V
T
D
A
V
R
E
I
R
R
A
L
T
D
G
E
G
RQR
V
P
L
I
G
F
S
G
S
P
W
T
L
A
C
Y
M
V
E
------
G
G
G
S
D
D
F
---
R
T
---
V
---
K
S
M
A
Y
A
R
P
D
L
M
H
R
I
L
D
V
N
A
Q
A
V
A
A
Y
L
N
A
Q
I
E
A
G
A
Q
A
V
M
I
F
D
T
W
G
G
A
L
A
D
G
A
Y
Q
R
F
S
L
D
Y
I
R
R
V
V
A
Q
L
K
----
R
E
----
H
D
-
G
A
R
---
V
P
A
I
A
F
T
K
G
-
G
G
L
W
L
E
D
L
A
A
T
G
V
D
A
V
G
L
D
W
T
V
N
L
G
R
A
R
E
R
V
AG
R
V
A
L
Q
G
N
L
D
P
T
I
L
-
F
A
P
P
E
A
I
-
R
A
E
A
R
A
V
L
D
----
S
Y
-
G
N
H
P
G
---
H
V
F
N
L
G
H
G
I
S
Q
F
T
P
P
E
H
V
A
E
L
V
D
E
V
H
R
H
22
PsiBlast_CBE
96.46
35%
-109
- C1 -
4WSH
7
DCUP_PSEAE
A:
[30-355]
------------------------------
P
V
W
M
M
R
Q
A
G
R
Y
L
P
E
Y
R
--
A
T
R
A
K
A
G
D
F
M
S
L
C
M
N
P
E
L
A
C
E
V
T
L
Q
P
L
D
R
Y
P
Q
L
D
A
A
I
L
F
S
D
I
L
T
I
P
D
A
M
G
Q
G
L
Y
F
E
T
G
E
G
P
R
----
F
-
R
K
V
V
S
S
L
A
---
D
I
E
A
L
P
--
V
P
D
--
P
--
E
Q
D
L
--
G
Y
V
M
D
A
V
R
T
I
R
R
E
L
N
G
R
V
P
-----
L
I
G
F
S
G
S
P
W
T
L
A
T
Y
M
V
E
------
G
G
S
S
K
D
F
---
R
K
S
K
A
M
---
L
Y
D
---
N
P
K
A
M
H
A
L
L
D
K
L
A
Q
S
V
T
S
Y
L
N
G
Q
I
H
A
G
A
Q
A
V
Q
I
F
D
S
W
G
G
S
L
S
A
A
A
Y
Q
E
F
S
L
A
Y
M
R
K
I
V
D
G
L
I
----
R
E
----
H
D
-
G
R
R
---
V
P
V
I
L
F
T
K
-
G
G
G
L
W
L
E
S
M
A
E
V
G
A
E
A
L
G
L
D
W
T
C
D
I
G
S
A
R
A
R
V
GE
R
V
A
L
Q
G
N
M
D
P
S
V
L
Y
A
N
P
A
A
I
R
-
A
-
E
V
A
R
I
L
A
----
A
Y
G
K
G
T
G
----
H
V
F
N
L
G
H
G
I
T
P
E
V
D
P
A
H
A
G
A
F
F
E
A
V
H
E
L
2
PsiBlast_PDB
95.88
34%
-104
- C1 -
3GW0
-
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
R
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
9
PsiBlast_PDB
95.74
34%
-104
- C1 -
3GW3
-
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GN
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
15
PsiBlast_PDB
95.71
34%
-104
- C1 -
1R3R
-
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
N
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
13
PsiBlast_PDB
95.64
34%
-105
- C1 -
1R3V
2
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
E
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
8
PsiBlast_PDB
95.60
34%
-105
- C1 -
3GVR
-
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
25
PsiBlast_CBE
95.42
36%
-128
- C1 -
2EJA
1
DCUP_AQUAE
A:
[18-334]
----------------------------
R
F
P
V
W
L
M
R
Q
A
G
R
Y
M
P
E
Y
R
--
K
I
R
N
R
V
K
N
F
L
E
L
C
K
N
V
D
L
A
T
E
I
S
L
L
P
L
K
I
L
-
G
V
D
A
I
I
I
F
S
D
I
L
V
P
L
E
P
L
G
V
K
V
E
F
V
E
G
E
G
P
K
----
L
-
S
W
S
----
G
---
K
V
S
D
L
K
KY
D
P
S
--
Q
--
N
A
Y
V
--
Y
E
I
I
K
R
V
K
E
A
Q
D
E
V
P
---------
V
I
G
F
A
G
A
P
F
T
L
L
S
Y
L
I
E
------
G
G
A
S
K
D
F
---
K
S
---
T
K
L
F
M
W
E
---
N
P
K
E
Y
K
R
L
M
D
I
L
T
E
T
V
L
A
Y
L
K
E
Q
I
K
A
G
A
D
V
V
Q
I
F
D
S
W
V
N
N
L
S
L
E
D
Y
G
E
Y
V
Y
P
Y
V
N
Y
L
I
S
E
L
K
-----
D
----
F
S
-
D
-----
T
P
V
I
Y
F
F
R
G
S
S
S
-
F
I
D
L
A
V
D
Y
R
A
D
A
L
S
V
D
W
S
V
D
I
P
E
L
F
K
I
Y
--
D
K
G
F
Q
G
N
L
E
P
A
V
L
-
Y
A
S
E
E
V
I
-
E
-
E
--
K
T
L
G
----
L
L
-
R
R
I
P
VKTR
Y
V
F
N
L
G
H
G
L
A
P
D
M
E
L
E
K
V
K
Y
L
V
D
L
V
K
S
F
1
PsiBlast_PDB
95.41
34%
-105
- C1 -
1JPH
-
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
T
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
17
PsiBlast_PDB
95.15
34%
-105
- C1 -
1R3T
1
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
G
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
21
PsiBlast_CBE
95.14
35%
-107
- C1 -
4WSH
3
DCUP_PSEAE
B:
[30-355]
------------------------------
P
V
W
M
M
R
Q
A
G
R
Y
L
P
E
Y
R
--
A
T
R
A
K
A
G
D
F
M
S
L
C
M
N
P
E
L
A
C
E
V
T
L
Q
P
L
D
R
Y
P
Q
L
D
A
A
I
L
F
S
D
I
L
T
I
P
D
A
M
G
Q
G
L
Y
------
P
R
----
F
-
R
K
V
V
S
S
L
A
---
D
I
E
A
L
P
--
V
P
D
--
P
--
E
Q
D
L
--
G
Y
V
M
D
A
V
R
T
I
R
R
E
L
N
G
R
V
P
-----
L
I
G
F
S
G
S
P
W
T
L
A
T
Y
M
V
E
------
G
G
S
S
K
D
F
---
R
K
S
K
A
M
---
L
Y
D
---
N
P
K
A
M
H
A
L
L
D
K
L
A
Q
S
V
T
S
Y
L
N
G
Q
I
H
A
G
A
Q
A
V
Q
I
F
D
S
W
G
G
S
L
S
A
A
A
Y
Q
E
F
S
L
A
Y
M
R
K
I
V
D
G
L
I
----
R
E
----
H
D
-
G
R
R
---
V
P
V
I
L
F
T
K
-
G
G
G
L
W
L
E
S
M
A
E
V
G
A
E
A
L
G
L
D
W
T
C
D
I
G
S
A
R
A
R
V
GE
R
V
A
L
Q
G
N
M
D
P
S
V
L
Y
A
N
P
A
A
I
R
-
A
-
E
V
A
R
I
L
A
----
A
Y
G
K
G
T
G
----
H
V
F
N
L
G
H
G
I
T
P
E
V
D
P
A
H
A
G
A
F
F
E
A
V
H
E
L
5
PsiBlast_PDB
95.13
34%
-105
- C1 -
1R3Q
2
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
6
PsiBlast_PDB
95.08
34%
-104
- C1 -
1R3Y
1
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
7
PsiBlast_PDB
95.06
34%
-105
- C1 -
3GVQ
-
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
20
PsiBlast_PDB
94.96
34%
-105
- C1 -
1JPK
-
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
D
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
16
PsiBlast_PDB
94.92
34%
-105
- C1 -
1R3S
1
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
G
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
19
PsiBlast_PDB
94.82
34%
-108
- C1 -
2Q6Z
-
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
R
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
11
PsiBlast_PDB
94.62
34%
-111
- C1 -
3GVV
-
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
Y
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
4
PsiBlast_PDB
94.49
34%
-104
- C1 -
1URO
1
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
3
PsiBlast_PDB
94.49
34%
-103
- C1 -
1JPI
-
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
L
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
18
PsiBlast_PDB
94.32
34%
-105
- C1 -
2Q71
1
DCUP_HUMAN
A:
[15-350]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
R
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
14
PsiBlast_PDB
94.25
34%
-105
- C1 -
1R3W
1
DCUP_HUMAN
A:
[25-360]
-----------------------
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
E
T
R
A
A
Q
D
---
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
D
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
FPEP
L
-
R
E
E
----
Q
---
D
L
E
R
L
R
--
D
P
E
--
V
V
-
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
F
M
V
E
------
G
G
G
S
S
T
M
---
A
Q
---
A
K
R
W
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
----
L
R
-
E
A
G
L
A
P
V
P
M
I
I
F
A
K
D
-
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
-
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
28
HHSearch
93.20
33%
-100
- C1 -
1R3S
1
DCUP_HUMAN
A:
[11-360]
--------
F
P
E
L
K
N
D
T
F
L
R
A
A
-
W
G
E
E
T
D
Y
T
P
V
W
C
M
R
Q
A
G
R
Y
L
P
E
F
R
--
E
-
T
R
A
A
Q
D
F
F
S
T
C
R
S
P
E
A
C
C
E
L
T
L
Q
P
L
R
R
F
-
P
L
D
A
A
I
I
F
S
G
I
L
V
V
P
Q
A
L
G
M
E
V
T
M
V
P
G
K
G
P
S
----
F
P
E
P
L
----
R
---
E
E
Q
D
L
E
--
R
L
R
DP
E
V
V
A
S
E
L
--
G
Y
V
F
Q
A
I
T
L
T
R
Q
R
L
A
G
R
V
P
-----
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
GGGSST
M
---
A
Q
A
---
K
R
---
W
---
L
Y
Q
---
R
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
V
P
Y
L
V
G
Q
V
V
A
G
A
Q
A
L
Q
L
F
E
S
H
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
Y
I
R
D
V
A
K
Q
V
K
----
A
R
L
R
E
A
G
L
A
P
-----
V
P
M
I
I
F
A
K
D
G
H
F
A
L
E
E
L
A
Q
A
-
G
Y
E
V
V
G
L
D
W
T
V
A
P
K
K
A
R
E
C
V
GK
T
V
T
L
Q
G
N
L
D
P
C
A
L
Y
A
-
S
E
E
E
I
G
Q
-
L
V
K
Q
M
L
D
----
D
F
-
G
P
H
R
----
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
23
PsiBlast_CBE
91.35
35%
-110
- C1 -
4ZR8
5
?
B:
[30-340]
------------------------------
P
I
W
M
M
R
Q
A
G
R
Y
L
P
E
Y
R
--
E
T
R
S
K
A
G
D
F
L
S
L
C
K
N
T
E
F
A
C
E
V
T
L
Q
P
L
R
R
Y
-
D
L
D
A
A
I
L
F
S
D
I
L
T
I
P
D
A
L
G
L
G
L
Y
F
E
T
G
E
G
P
K
----
F
H
K
T
V
----
R
---
T
E
Q
D
V
A
--
N
L
P
--
K
L
-
N
A
K
A
DL
D
Y
V
M
N
A
V
S
T
I
R
S
A
L
G
G
Q
V
P
-----
L
I
G
F
S
G
S
P
W
T
L
A
T
Y
M
V
E
------
G
G
S
S
K
E
F
R
F
T
K
Q
---
M
---
M
Y
A
---
Q
P
E
V
L
H
A
L
L
D
H
L
A
D
S
V
I
D
Y
L
N
A
Q
I
D
A
G
A
Q
A
I
Q
I
F
D
S
W
G
G
A
L
A
H
R
E
Y
V
E
F
S
L
N
Y
M
K
K
I
I
A
G
L
Q
REKD
G
R
-------
R
-----
I
P
V
I
V
F
T
K
G
G
G
Q
W
L
E
P
M
I
-
T
T
G
A
D
A
L
G
L
D
W
T
T
P
L
N
T
A
R
T
T
V
AG
R
V
A
L
Q
G
N
L
D
P
A
V
L
Y
G
S
A
A
S
I
E
-
K
-
A
V
K
A
M
L
D
D
A
Y
A
N
G
-
E
K
T
G
----
Y
V
A
N
L
G
H
G
I
T
Q
W
V
D
P
A
Q
P
K
I
F
V
D
T
V
H
E
Y
24
PsiBlast_CBE
91.12
35%
-110
- C1 -
4ZR8
6
?
A:
[30-340]
------------------------------
P
I
W
M
M
R
Q
A
G
R
Y
L
P
E
Y
R
--
E
T
R
S
K
A
G
--
L
S
L
C
K
N
T
E
F
A
C
E
V
T
L
Q
P
L
R
R
Y
-
D
L
D
A
A
I
L
F
S
D
I
L
T
I
P
D
A
L
G
L
G
L
Y
F
E
T
G
E
G
P
K
----
F
H
K
T
V
----
R
---
T
E
Q
D
V
A
--
N
L
P
--
K
L
-
N
A
K
A
DL
D
Y
V
M
N
A
V
S
T
I
R
S
A
L
G
G
Q
V
P
-----
L
I
G
F
S
G
S
P
W
T
L
A
T
Y
M
V
E
------
G
G
S
S
K
E
F
R
F
T
K
Q
---
M
---
M
Y
A
---
Q
P
E
V
L
H
A
L
L
D
H
L
A
D
S
V
I
D
Y
L
N
A
Q
I
D
A
G
A
Q
A
I
Q
I
F
D
S
W
G
G
A
L
A
H
R
E
Y
V
E
F
S
L
N
Y
M
K
K
I
I
A
G
L
Q
REKD
G
R
-------
R
-----
I
P
V
I
V
F
T
K
G
G
G
Q
W
L
E
P
M
I
-
T
T
G
A
D
A
L
G
L
D
W
T
T
P
L
N
T
A
R
T
T
V
AG
R
V
A
L
Q
G
N
L
D
P
A
V
L
Y
G
S
A
A
S
I
E
-
K
-
A
V
K
A
M
L
D
D
A
Y
A
N
G
-
E
K
T
G
----
Y
V
A
N
L
G
H
G
I
T
Q
W
V
D
P
A
Q
P
K
I
F
V
D
T
V
H
E
Y