@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0428: (2015-12-01 )
MDFAVRYKITIEYNGSSFSGWQKQQHSANSIQETIENAIFNFSGEKVTLHCGGRTDAGVHALGQVAHFDMERKFELYKIRNAINYHLKSIPIVVLNAETVDNTFHSRFSAKKRYYEYRIINRYAPAALEAGYAWQVFNPLDVNIMREAAKYLLGKHNLLSFRSKDCQATNPIRTIDDIDIVQNGSHIYIKISAISFLHNQVRIIVGTLVEFGKSRTNPQKMLNILNQCKRNAAGVTAPPFGLYLAKIDY
Atome Classification :
(20 SA)
-------------------------------------------------------------------.......-----.---.10-.......--..20.-------------...-....--30........-40-..------.-.---....50........--60...-------------.....70--.----..---..---...80........90.....-------...100------------...-.....---.-110--....--...120.--...-.----...130-.......140------------------------------------.......150.---.--....-.-160.-......------170.------.....----.180.----....----------..190-..-.-------------------....---.200.......210----------------........220.....---------------..230.......240.......---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------MD
F
A
V
R
Y
-----
K
---
I
T
--
I
E
YNGSS--FS
G
W
Q
-------------
K
QQ-HS
A
N
--
S
I
Q
E
T
I
E
N
A
I
-FN-FS------G-
E
---
K
V
T
L
H
CGGRT
D
A
G
V
--
H
A
L
G
Q
-------------
V
A
H
F
D
M
E
--
R
----
K
F
---
E
L
---
Y
K
I
R
N
A
I
N
Y
H
LKSI
P
I
V
V
L
N-------AETV--------------
D
N
T
-
F
H
S
R
F
---
S
-
A
K
K
--
R
Y
Y
E
--
Y
R
I
I
N-R--YA
P
-
A
----
A
LEAG
Y
-
A
W
Q
VFNPL
D
V
------------------------------------
N
I
M
R
E
A
A
K
Y
L
L---G--K
H
N
L
-
L
-
S
F
RS-KDCQAT------NPIR------TIDD
I
----
D
I
VQN----G
S
H
I
----------
Y
I
K
I
--
S
A
-
I
-------------------
S
F
L
H
---
N
Q
V
R
I
I
V
G
T
L
V
E
F-----------------GKSRT
N
P
Q
K
M
L
N
I
L
N
Q
---------------
C
K
RNAAGVTAPPF
G
L
Y
L
A
KIDY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
99.00
39%
-111
- C4 -
2NQP
-
TRUA_ECOLI
A:
[10-252]
-------------------------------------------------------------------------
Y
-----
K
---
I
A
L
G
I
E
Y
D
G
S
K
--
Y
Y
G
W
Q
-------------
R
Q
--
N
E
V
R
--
S
V
Q
E
K
L
E
K
A
L
-
S
Q
-
V
A
------
N
-
E
---
P
I
T
V
F
C
A
G
R
T
D
A
G
V
--
H
G
T
G
Q
-------------
V
V
H
F
E
T
T
A
L
R
----
K
D
---
A
A
---
W
T
L
--
G
V
N
A
N
L
P
G
-
D
I
A
V
R
W
-------
V
K
T
V
--------------
P
D
D
-
F
H
A
R
F
---
S
-
A
T
A
--
R
R
Y
R
--
Y
I
I
Y
N
H
R
--
L
R
P
-
A
----
V
L
S
K
G
V
-
T
-
H
F
Y
E
P
L
D
A
------------------------------------
E
R
M
H
R
A
A
Q
C
L
L
---
G
--
E
N
D
F
-
T
-
S
F
R
A
-
V
Q
C
Q
S
R
------
T
P
W
R
------
N
V
M
H
I
----
N
V
T
R
H
----
G
P
Y
V
----------
V
V
D
I
--
K
A
-
N
-------------------
A
F
V
H
---
H
M
V
R
N
I
V
G
S
L
M
E
V
-----------------
G
A
H
N
Q
P
E
S
W
I
A
E
L
L
A
A
---------------
K
D
R
T
L
A
A
A
T
A
K
A
E
G
L
Y
L
V
A
V
D
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
98.89
39%
-111
- C4 -
2NQP
1
TRUA_ECOLI
C:
[10-252]
-------------------------------------------------------------------------
Y
-----
K
---
I
A
LG
I
E
Y
D
G
S
K
--
Y
Y
G
W
Q
-------------
R
Q
--
N
E
V
R
--
S
V
Q
E
K
L
E
K
A
L
-
S
Q
-
V
A
------
N
-
E
---
P
I
T
V
F
C
A
G
R
T
D
A
G
V
--
H
G
T
G
Q
-------------
V
V
H
F
E
T
T
AL
R
----
K
D
---
A
A
---
W
T
L
--
G
V
N
A
N
L
P
G
-
D
I
A
V
R
W
-------
V
K
T
V
--------------
P
D
D
-
F
H
A
R
F
---
S
-
A
T
A
--
R
R
Y
R
--
Y
I
I
Y
N
H
R
--
L
R
P
-
A
----
V
L
S
K
G
V
-
T
-
H
F
Y
E
P
L
D
A
------------------------------------
E
R
M
H
R
A
A
Q
C
L
L
---
G
--
E
N
D
F
-
T
-
S
F
R
A
-
V
Q
C
Q
S
R
------
T
P
W
R
------
N
V
M
H
I
----
N
V
T
R
H
----
G
P
Y
V
----------
V
V
D
I
--
K
A
-
N
-------------------
A
F
V
H
---
H
M
V
R
N
I
V
G
S
L
M
E
V
-----------------
G
A
H
N
Q
P
E
S
W
I
A
E
L
L
A
A
---------------
K
D
R
T
L
A
A
A
T
A
K
A
E
G
L
Y
L
V
A
V
D
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
Fugue
98.19
36%
-110
- C4 -
1DJ0
1
TRUA_ECOLI
A:
[1-264]
--------------------------------------------------------------------
P
P
V
Y
K
I
-----
A
---
L
G
--
I
E
Y
D
G
S
K
--
Y
Y
G
W
Q
-------------
R
Q
N
-
E
V
-
R
--
S
V
Q
E
K
L
E
K
A
L
-
S
Q
-
V
A
------
N
-
E
---
P
I
T
V
F
C
A
G
R
T
D
A
G
V
--
H
G
T
G
Q
-------------
V
V
H
F
E
T
T
--
A
----
L
R
---
K
D
---
A
A
W
T
L
G
V
N
A
N
L
P
G
-
D
I
A
V
R
W
-------
V
K
T
V
--------------
P
D
D
-
F
H
A
R
F
---
S
-
A
T
A
--
R
R
Y
R
--
Y
I
I
Y
N
-
H
--
R
L
R
-
P
----
A
V
L
S
K
G
-
V
T
H
F
Y
E
P
L
D
A
------------------------------------
E
R
M
H
R
A
A
Q
C
L
L
---
G
--
E
N
D
F
-
T
-
S
F
R
A
-
V
Q
C
Q
S
R
------
T
P
W
R
------
N
V
M
H
I
----
N
V
T
R
H
----
G
P
Y
V
----------
V
V
D
I
--
K
A
-
N
-------------------
A
F
V
H
---
H
M
V
R
N
I
V
G
S
L
M
E
V
-----------------
G
A
H
N
Q
P
E
S
W
I
A
E
L
L
A
A
---------------
K
D
R
T
L
A
A
A
T
A
K
A
E
G
L
Y
L
V
A
V
D
Y
PDRYD
L
P
K
P
PMGPLFLAD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
98.07
39%
-109
- C4 -
1DJ0
1
TRUA_ECOLI
A:
[4-246]
-------------------------------------------------------------------------
Y
-----
K
---
I
A
L
G
I
E
Y
D
G
S
K
--
Y
Y
G
W
Q
-------------
R
Q
--
N
E
V
R
--
S
V
Q
E
K
L
E
K
A
L
-
S
Q
-
V
A
------
N
-
E
---
P
I
T
V
F
C
A
G
R
T
D
A
G
V
--
H
G
T
G
Q
-------------
V
V
H
F
E
T
T
A
L
R
----
K
D
---
A
A
---
W
T
L
--
G
V
N
A
N
L
P
G
-
D
I
A
V
R
W
-------
V
K
T
V
--------------
P
D
D
-
F
H
A
R
F
---
S
-
A
T
A
--
R
R
Y
R
--
Y
I
I
Y
N
H
R
--
L
R
P
-
A
----
V
L
S
K
G
V
-
T
-
H
F
Y
E
P
L
D
A
------------------------------------
E
R
M
H
R
A
A
Q
C
L
L
---
G
--
E
N
D
F
-
T
-
S
F
R
A
-
V
Q
C
Q
S
R
------
T
P
W
R
------
N
V
M
H
I
----
N
V
T
R
H
----
G
P
Y
V
----------
V
V
D
I
--
K
A
-
N
-------------------
A
F
V
H
---
H
M
V
R
N
I
V
G
S
L
M
E
V
-----------------
G
A
H
N
Q
P
E
S
W
I
A
E
L
L
A
A
---------------
K
D
R
T
L
A
A
A
T
A
K
A
E
G
L
Y
L
V
A
V
D
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
97.24
39%
-108
- C4 -
2NR0
-
TRUA_ECOLI
A:
[10-252]
-------------------------------------------------------------------------
Y
-----
K
---
I
A
L
G
I
E
Y
D
G
S
K
--
Y
Y
G
W
Q
-------------
R
Q
--
N
E
V
R
--
S
V
Q
E
K
L
E
K
A
L
-
S
Q
-
V
A
------
N
-
E
---
P
I
T
V
F
C
A
G
R
T
D
A
G
V
--
H
G
T
G
Q
-------------
V
V
H
F
E
T
T
AL
R
----
K
D
---
A
A
---
W
T
L
--
G
V
N
A
N
L
P
G
-
D
I
A
V
R
W
-------
V
K
T
V
--------------
P
D
D
-
F
H
A
R
F
---
S
-
A
T
A
--
R
R
Y
R
--
Y
I
I
Y
N
H
R
--
L
R
P
-
A
----
V
L
S
K
G
V
-
T
-
H
F
Y
E
P
L
D
A
------------------------------------
E
R
M
H
R
A
A
Q
C
L
L
---
G
--
E
N
D
F
-
T
-
S
F
R
A
-
V
Q
C
Q
S
R
------
T
P
W
R
------
N
V
M
H
I
----
N
V
T
R
H
----
G
P
Y
V
----------
V
V
D
I
--
K
A
-
N
-------------------
A
F
V
H
---
H
M
V
R
N
I
V
G
S
L
M
E
V
-----------------
G
A
H
N
Q
P
E
S
W
I
A
E
L
L
A
A
---------------
K
D
R
T
L
A
A
A
T
A
K
A
E
G
L
Y
L
V
A
V
D
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
96.89
39%
-111
- C4 -
1DJ0
1
TRUA_ECOLI
B:
[4-246]
-------------------------------------------------------------------------
Y
-----
K
---
I
A
LG
I
E
Y
D
G
S
K
--
Y
Y
G
W
Q
-------------
R
Q
--
N
E
V
R
--
S
V
Q
E
K
L
E
K
A
L
-
S
Q
-
V
A
------
N
-
E
---
P
I
T
V
F
C
A
G
R
T
D
A
G
V
--
H
G
T
G
Q
-------------
V
V
H
F
E
T
T
AL
R
----
K
D
---
A
A
---
W
T
L
--
G
V
N
A
N
L
P
G
-
D
I
A
V
R
W
-------
V
K
T
V
--------------
P
D
D
-
F
H
A
R
F
---
S
-
A
T
A
--
R
R
Y
R
--
Y
I
I
Y
N
H
R
--
L
R
P
-
A
----
V
L
S
K
G
V
-
T
-
H
F
Y
E
P
L
D
A
------------------------------------
E
R
M
H
R
A
A
Q
C
L
L
---
G
--
E
N
D
F
-
T
-
S
F
R
A
-
V
Q
C
Q
S
R
------
T
P
W
R
------
N
V
M
H
I
----
N
V
T
R
H
----
G
P
Y
V
----------
V
V
D
I
--
K
A
-
N
-------------------
A
F
V
H
---
H
M
V
R
N
I
V
G
S
L
M
E
V
-----------------
G
A
H
N
Q
P
E
S
W
I
A
E
L
L
A
A
---------------
K
D
R
T
L
A
A
A
T
A
K
A
E
G
L
Y
L
V
A
V
D
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
96.86
36%
-111
- C4 -
1DJ0
1
TRUA_ECOLI
A:
[2-246]
---------------------------------------------------------------------
P
V
Y
K
I
-----
A
---
L
G
--
I
E
Y
D
G
S
K
--
Y
Y
G
W
Q
-------------
R
Q
N
-
E
V
-
R
--
S
V
Q
E
K
L
E
K
A
L
-
S
Q
-
V
A
------
N
-
E
---
P
I
T
V
F
C
A
G
R
T
D
A
G
V
--
H
G
T
G
Q
-------------
V
V
H
F
E
T
T
--
A
----
L
R
---
K
D
---
A
A
W
T
L
G
V
N
A
N
L
P
-
G
D
I
A
V
R
W
-------
V
K
T
V
--------------
P
D
D
-
F
H
A
R
F
---
S
-
A
T
A
--
R
R
Y
R
--
Y
I
I
Y
N
-
H
--
R
L
R
-
P
----
A
V
L
S
K
G
-
V
T
H
F
Y
E
P
L
D
A
------------------------------------
E
R
M
H
R
A
A
Q
C
L
L
---
G
--
E
N
D
F
-
T
-
S
F
R
A
-
V
Q
C
Q
S
R
------
T
P
W
R
------
N
V
M
H
I
----
N
V
T
R
H
----
G
P
Y
V
----------
V
V
D
I
--
K
A
-
N
-------------------
A
F
V
H
---
H
M
V
R
N
I
V
G
S
L
M
E
V
-----------------
G
A
H
N
Q
P
E
S
W
I
A
E
L
L
A
A
---------------
K
D
R
T
L
A
A
A
T
A
K
A
E
G
L
Y
L
V
A
V
D
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
95.37
39%
-107
- C4 -
2NRE
-
TRUA_ECOLI
A:
[10-252]
-------------------------------------------------------------------------
Y
-----
K
---
I
A
L
G
I
E
Y
D
G
S
K
--
Y
Y
G
W
Q
-------------
R
Q
--
N
E
V
R
--
S
V
Q
E
K
L
E
K
A
L
-
S
Q
-
V
A
------
N
-
E
---
P
I
T
V
F
C
A
G
R
T
D
A
G
V
--
H
G
T
G
Q
-------------
V
V
H
F
E
T
T
AL
R
----
K
D
---
A
A
---
W
T
L
--
G
V
N
A
N
L
P
G
-
D
I
A
V
R
W
-------
V
K
T
V
--------------
P
D
D
-
F
H
A
R
F
---
S
-
A
T
A
--
R
R
Y
R
--
Y
I
I
Y
N
H
R
--
L
R
P
-
A
----
V
L
S
K
G
V
-
T
-
H
F
Y
E
P
L
D
A
------------------------------------
E
R
M
H
R
A
A
Q
C
L
L
---
G
--
E
N
D
F
-
T
-
S
F
R
A
-
V
-----------
T
P
W
R
------
N
V
M
H
I
----
N
V
T
R
H
----
G
P
Y
V
----------
V
V
D
I
--
K
A
-
N
-------------------
A
F
V
H
---
H
M
V
R
N
I
V
G
S
L
M
E
V
-----------------
G
A
H
N
Q
P
E
S
W
I
A
E
L
L
A
A
---------------
K
D
R
T
L
A
A
A
T
A
K
A
E
G
L
Y
L
V
A
V
D
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
HHSearch
91.11
35%
-101
- C4 -
1VS3
-
TRUA_THET8
A:
[1-246]
----------------------------------------------------------------------
M
R
R
L
-----
L
---
L
L
--
C
E
Y
D
G
T
L
--
F
A
G
L
Q
-------------
R
Q
G
R
G
L
-
R
--
T
V
Q
G
E
L
E
R
A
L
-
P
G
-
I
G
------
A
-----
L
P
K
A
V
A
A
G
R
T
D
A
G
V
--
H
A
L
A
M
-------------
P
F
H
V
D
V
E
--
S
----
A
I
---
P
V
---
E
K
V
P
E
A
L
N
R
L
L
P
-
E
D
L
K
V
V
G
-------
A
R
E
V
--------------
A
P
D
-
F
H
A
R
K
---
D
-
A
L
W
--
R
A
Y
R
--
Y
R
I
L
V
-
R
--
P
H
P
-
S
----
P
L
L
R
H
R
-
A
L
W
V
R
R
P
L
D
L
------------------------------------
E
A
M
E
E
A
L
S
L
L
L
---
G
--
R
H
N
F
-
L
-
G
F
A
K
-
E
E
T
--
R
------
P
G
E
R
------
E
L
L
E
A
----
R
L
Q
V
A
EGEA
G
L
E
V
----------
R
L
Y
F
--
R
G
-
K
-------------------
S
F
L
R
---
G
Q
V
R
G
M
V
G
T
L
L
E
V
-----------------
G
L
G
K
R
P
P
E
S
L
K
A
I
L
K
T
---------------
A
D
R
R
L
A
G
P
T
A
P
A
H
G
L
Y
F
V
E
A
A
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
89.29
34%
-94
- C4 -
1VS3
-
TRUA_THET8
A:
[3-246]
------------------------------------------------------------------------
R
L
-----
L
---
L
L
--
C
E
Y
D
G
T
L
--
F
A
G
L
Q
-------------
R
Q
G
-
R
G
L
R
--
T
V
Q
G
E
L
E
R
A
L
-
P
G
-
I
-------
G
-
A
---
L
P
K
A
V
A
A
G
R
T
D
A
G
V
--
H
A
L
A
M
-------------
P
F
H
V
D
V
E
--
S
----
A
I
---
P
V
---
E
K
V
P
E
A
L
N
R
L
L
P
E
D
-
L
K
V
V
G
-------
A
R
E
V
--------------
A
P
D
-
F
H
A
R
K
---
D
-
A
L
W
--
R
A
Y
R
--
Y
R
I
L
V
-
R
--
P
H
P
-
S
----
P
L
L
R
H
R
-
A
L
W
V
R
R
P
L
D
L
------------------------------------
E
A
M
E
E
A
L
S
L
L
L
---
G
--
R
H
N
F
-
L
-
G
F
A
K
-
E
E
T
R
P
G
------
E
R
E
L
------
L
E
A
R
L
----
Q
V
A
E
G
----
E
A
G
L
----------
E
V
R
L
Y
F
R
G
-
K
-------------------
S
F
L
R
---
G
Q
V
R
G
M
V
G
T
L
L
E
V
-----------------
G
L
G
K
R
P
P
E
S
L
K
A
I
L
K
T
---------------
A
D
R
R
L
A
G
P
T
A
P
A
H
G
L
Y
F
V
E
A
A
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
80.77
24%
-99
- C4 -
4IQM
-
TRUA_HUMAN
A:
[16-268]
-----------------------------------------------------------------------------------
L
L
--
M
A
Y
S
G
K
G
--
Y
H
G
M
Q
-------------
R
N
------FK
T
I
E
D
D
L
V
S
A
L
-
V
R
-
S
G
CIP
E
N
H
G
-
E
D
MR
K
M
S
F
Q
R
C
A
R
T
D
K
G
V
--
S
A
A
G
Q
-------------
V
V
S
L
K
V
---------
W
---
L
I
---
D
D
I
L
E
K
I
N
S
H
L
P
S
-
H
I
R
I
L
G
-------
L
K
R
V
--------------
T
G
G
-
F
N
S
K
N
---
R
-
C
D
A
--
R
T
Y
C
--
Y
-
L
L
P
-
T
--
F
A
F
-
A
----
H
K
D
R
D
V
-
Q
D
E
T
Y
R
-
L
S
A
------------------------------------
E
T
L
Q
Q
V
N
R
L
L
A
C
Y
K
G
--
T
H
N
F
-
H
-
N
F
T
S
Q
K
G
P
Q
D
P
------
S
A
C
R
------
Y
I
L
E
M
Y
C
E
E
P
F
V
R
E
----
G
L
E
F
A
---------
V
I
R
V
--
K
G
-
Q
-------------------
S
F
M
M
---
H
Q
I
R
K
M
V
G
L
V
V
A
I
-----------------
V
K
G
Y
A
-
P
E
S
V
L
E
-
R
S
W
---------------
G
T
E
K
V
D
V
P
K
A
P
G
L
G
L
V
L
E
R
V
H
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
80.47
24%
-113
- C4 -
4ITS
5
TRUA_HUMAN
A:
[16-268]
-----------------------------------------------------------------------------------
L
L
--
M
A
Y
S
G
K
G
--
Y
H
G
M
Q
-------------
R
------
Q
FK
T
I
E
D
D
L
V
S
A
L
-
V
R
-
S
G
CIP
E
N
H
G
-
E
D
MR
K
M
S
F
Q
R
C
A
R
T
D
K
G
V
--
S
A
A
G
Q
-------------
V
V
S
L
K
V
---------
W
---
L
I
---
D
D
I
L
E
K
I
N
S
H
L
P
S
-
H
I
R
I
L
G
-------
L
K
R
V
--------------
T
G
G
-
F
N
--------
C
D
A
--
R
T
Y
C
--
Y
-
L
L
P
-
T
--
F
A
F
-
A
----
H
K
D
R
D
V
-
Q
D
E
T
Y
R
-
L
S
A
------------------------------------
E
T
L
Q
Q
V
N
R
L
L
A
C
Y
K
G
--
T
H
N
F
-
H
-
N
F
T
S
Q
K
G
P
Q
D
P
------
S
A
C
R
------
Y
I
L
E
M
Y
C
E
E
P
F
V
R
E
----
G
L
E
F
A
---------
V
I
R
V
--
K
G
-
Q
-------------------
S
F
M
M
---
H
Q
I
R
K
M
V
G
L
V
V
A
I
-----------------
V
K
G
Y
A
-
P
E
S
V
L
E
-
R
S
W
---------------
G
T
E
K
V
D
V
P
K
A
P
G
L
G
L
V
L
E
R
V
H
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
79.99
24%
-103
- C4 -
4NZ6
3
TRUA_HUMAN
A:
[7-259]
-----------------------------------------------------------------------------------
L
L
--
M
A
Y
S
G
K
G
--
Y
H
G
M
Q
-------------
R
------
Q
FK
T
I
E
D
D
L
V
S
A
L
-
V
R
-
S
G
CIP
E
N
H
G
-
E
D
MR
K
M
S
F
Q
R
C
A
R
T
D
K
G
V
--
S
A
A
G
Q
-------------
V
V
S
L
K
V
---------
W
---
L
I
---
D
D
I
L
E
K
I
N
S
H
L
P
S
-
H
I
R
I
L
G
-------
L
K
R
V
--------------
T
G
G
-
F
N
S
K
N
---
R
-
C
D
A
--
R
T
Y
C
--
Y
-
L
L
P
-
T
--
F
A
F
-
A
----
H
K
D
R
D
V
-
Q
D
E
T
Y
R
-
L
S
A
------------------------------------
E
T
L
Q
Q
V
N
R
L
L
A
C
Y
K
G
--
T
H
N
F
-
H
-
N
F
T
S
Q
K
G
P
Q
D
P
------
S
A
C
R
------
Y
I
L
E
M
Y
C
E
E
P
F
V
R
E
----
G
L
E
F
A
---------
V
I
R
V
--
K
G
-
Q
-------------------
S
F
M
M
---
H
Q
I
R
K
M
V
G
L
V
V
A
I
-----------------
V
K
G
Y
A
-
P
E
S
V
L
E
-
R
S
W
---------------
G
T
E
K
V
D
V
P
K
A
P
G
L
G
L
V
L
E
R
V
H
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
79.97
24%
-106
- C4 -
4NZ7
2
TRUA_HUMAN
A:
[7-259]
-----------------------------------------------------------------------------------
L
L
--
M
A
Y
S
G
K
G
--
Y
H
G
M
Q
--------------------
Q
FK
T
I
E
D
D
L
V
S
A
L
-
V
R
-
S
G
CIP
E
N
H
G
-
E
DMR
K
M
S
F
Q
R
C
A
R
T
A
K
G
V
--
S
A
A
G
Q
-------------
V
V
S
L
K
V
---------
W
---
L
I
---
D
D
I
L
E
K
I
N
S
H
L
P
S
-
H
I
R
I
L
G
-------
L
K
R
V
--------------
T
G
G
-
F
N
S
K
N
---
R
-
C
D
A
--
R
T
Y
C
--
Y
-
L
L
P
-
T
--
F
A
F
-
A
----
H
K
D
R
D
V
-
Q
D
E
T
Y
R
-
L
S
A
------------------------------------
E
T
L
Q
Q
V
N
R
L
L
A
C
Y
K
G
--
T
H
N
F
-
H
-
N
F
T
S
Q
K
G
P
Q
D
P
------
S
A
C
R
------
Y
I
L
E
M
Y
C
E
E
P
F
V
R
E
----
G
L
E
F
A
---------
V
I
R
V
--
K
G
-
Q
-------------------
S
F
M
M
---
H
Q
I
R
K
M
V
G
L
V
V
A
I
-----------------
V
K
G
Y
A
-
P
E
S
V
L
E
-
R
S
W
---------------
G
T
E
K
V
D
V
P
K
A
P
G
L
G
L
V
L
E
R
V
H
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
Fugue
54.88
15%
-56
- C2 -
1WA9
-
PER_DROME
A:
[237-571]
---------------------------------------------------------E
D
S
F
C
C
V
I
S
M
H
D
G
I
V
L
Y
TTPSI
T
---
D
V
--
L
G
Y
P
R
D
M
--
W
L
G
R
S
-------------
F
I
D
-
F
V
H
L
--
K
D
R
A
T
F
A
S
Q
I
T
T
G
-
I
A
------
K
-
S
---
T
F
C
V
M
L
R
R
Y
R
G
L
K
S
--
G
G
F
G
V
-------------
I
G
R
P
V
S
Y
--
E
----
P
F
---
R
L
G
L
T
F
R
E
A
P
E
E
A
R
S
N
G
T
N
M
L
L
V
I
C
-------
A
T
P
I
K
S
SYKVPDEILSQK
S
P
K
-
F
A
I
R
H
---
T
-
A
T
G
II
S
H
V
D
--
S
A
A
V
S
-
A
LG
Y
L
P
-
Q
----
D
L
I
G
R
S
-
I
M
D
F
Y
H
H
E
D
L
------------------------------------
S
V
M
K
E
T
Y
E
T
V
M
---
K
--
K
G
Q
------
T
A
-
G
A
S
F
C
S
------
K
P
Y
R
------
F
L
---------
I
Q
N
----
G
C
Y
V
----------
L
L
E
T
--
E
W
-
T
-------------------
S
F
V
N
PWS
R
K
L
E
F
V
V
G
H
H
R
V
F
QGPKQCNVF
E
A
A
P
T
C
K
L
K
I
S
E
E
A
Q
S
R
N
T
R
I
K
E
D
---------------
I
V
K
R
L
A
E
T
V
S
R
P
S
D
T
V
K
Q
E
V
S
R
R
C
Q
A
L
A
S
F
M
E
T
L
M
D
E
V
S
RAD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
HHSearch
47.28
18%
-78
- C4 -
2V9K
5
PUS10_HUMAN
A:
[317-469]
-------------------------------------------------------------------------------------------------------------------------
S
--
S
V
E
E
L
I
S
D
H
L
-
L
A
-
V
F
------
K
A
E
---
S
F
N
F
S
S
S
G
R
E
D
V
D
V
--
R
T
L
G
N
-------------
G
R
P
F
A
I
E
L
V
N
PHRV
H
F
T
S
Q
E
I
---
K
E
L
Q
Q
K
I
N
N
S
-
S
-
N
K
I
Q
V
R
D
-------
L
Q
L
V
--------------
T
R
E
A
I
G
H
M
K
E
G
E
E
-
E
K
T
--
K
T
Y
S
--
A
L
I
W
T
-
N
--
K
---------------------
A
I
Q
K
------------------------------------
K
D
I
E
F
L
N
D
I
K
D
---
L
--
K
I
D
Q
K
T
P
L
R
V
L
-
H
R
R
P
L
A
------
V
R
A
R
------
V
I
H
F
M
----
E
T
Q
Y
V
----
D
E
H
H
----------
F
R
L
H
--
L
K
-
T
-------------------
Q
A
G
T
---
Y
I
K
E
F
V
H
G
D
F
G
R
T
-----------------
K
P
N
I
G
S
L
M
N
V
T
A
D
I
L
E
---------------
L
D
V
E
S
V
D
V
D
W
P
P
A
L
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
Fugue
46.47
11%
-53
- C4 -
2C0H
1
MANA_MYTED
A:
[1-353]
------------------------------------------------------------------A
A
V
R
L
S
V
S
-----
G
---
T
N
--
L
N
Y
N
G
H
H
I
F
L
S
G
A
N
QAWVNYARDFGHN
Q
Y
S
-
K
G
K
S
--
T
F
E
S
T
L
S
D
M
Q
-
S
H
G
G
N
------
S
-
V
---
R
V
W
L
H
I
E
G
E
S
T
P
E
F
--
D
N
N
G
Y
-------------
V
T
G
I
D
N
T
--
L
----
I
S
---
D
M
---
R
A
Y
L
H
A
A
Q
R
H
N
I
L
I
F
F
T
L
W
N
GAVKQST
H
Y
R
L
--------------
N
G
L
-
M
V
D
T
R
---
K
-
L
Q
S
--
Y
I
D
H
A
L
K
P
M
A
N
-
A
--
L
K
N
-
E
------
K
A
L
G
-
G
W
D
I
M
N
E
P
E
G
EIKPGESSSEPCFDTRHLSGSGAGWAGHLYS
A
Q
E
I
G
R
F
V
N
W
Q
A
A
A
I
K
---
E
V
D
P
G
A
M
-
V
-
T
V
G
S
-
W
N
M
K
A
D
------
T
D
A
M
GFHNLY
S
D
H
C
L
----
V
K
A
G
G
----
K
Q
S
G
----------
T
L
S
F
--
Y
Q
-
V
H
T
Y
D
W
QNHFGNESPFKHSF
S
N
F
R
---
L
K
K
P
M
V
I
G
E
F
N
Q
E
-----------------
H
G
A
G
M
S
S
E
S
M
F
E
W
A
Y
T
K
GYS
G
A
W
T
WSRTDVS
W
N
N
Q
L
R
G
M
Q
H
L
K
S
R
T
D
H
G
Q
V
Q
F
GL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
Fugue
45.93
12%
-32
- C5 -
2A1F
-
PYRH_HAEIN
A:
[1-239]
-------------------------------------------------------------------
L
S
Q
P
I
Y
K
-----
R
---
I
L
--
L
K
L
S
G
E
A
--
L
Q
G
E
D
-------------
G
L
G
-
I
D
P
A
--
I
L
D
R
M
A
V
E
I
K
-
E
L
-
V
E
M
-----
G
-
V
---
E
V
S
V
V
L
G
G
----
G
N
--
L
F
R
G
A
-------------
K
L
A
K
A
G
M
--
N
----
R
V
---
V
G
---
D
H
M
G
M
L
A
T
V
M
N
G
L
A
M
R
D
S
L
F
-------
R
A
D
V
--------------
N
A
K
-
L
M
S
A
F
---
Q
-
L
N
G
--
I
C
D
T
--
Y
N
--
W
-
S
--
E
A
I
-
K
----
M
L
R
E
K
R
---------
V
V
------------------------------------
I
F
S
A
G
T
G
N
P
F
F
---
T
--
T
D
S
T
-
A
-
C
L
R
G
-
I
E
I
E
A
-------
D
V
V
L
------
K
A
T
K
V
----
D
G
V
Y
D
----
C
A
K
L
----------
Y
K
N
L
--
S
Y
-
A
-------------------
E
V
I
D
---
K
E
L
K
V
M
D
L
S
A
F
T
L
-----------------
A
R
D
H
G
M
P
I
R
V
F
N
M
G
K
P
----------------
G
A
L
R
Q
V
V
T
G
T
E
E
G
T
T
I
C
E
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
Fugue
45.60
16%
-34
* C5 *
3VRH
3
?
A:
[1-309]
-------------------------------------------------------------------
M
K
C
K
F
C
S
-----
R
EAY
I
K
--
I
H
Y
P
K
M
Y
--
L
C
E
E
H
-------------
F
K
E
-
Y
F
E
R
--
K
V
S
R
T
I
E
R
Y
K
-
L
L
-
T
K
------
D
-
E
---
R
I
L
V
A
V
S
G
G
K
D
S
A
V
T
A
Y
V
L
K
K
L
GYN
I
E
C
L
H
I
N
LG
I
S
G
Y
S
E
K
--
S
----
E
E
---
Y
A
---
K
K
Q
C
K
L
I
G
A
P
L
H
I
V
R
I
K
E
I
L
-------
G
Y
G
I
--------------
G
E
V
-
K
T
R
R
P
---
P
C
S
Y
C
--
G
L
T
K
--
R
Y
I
M
N
-
K
--
F
A
Y
-
D
N
GFD
A
I
A
T
G
H
N
L
D
D
E
A
S
F
L
L
N
------------------------------------
N
I
L
H
W
N
T
E
Y
L
A
---
K
--
G
G
P
I
-
L
-
P
Q
Q
G
-
K
F
I
K
K
V
------
K
P
L
Y
------
E
V
T
E
R
----
E
V
V
A
Y
----
A
L
A
V
G
L
E
Y
I
VEECP
Y
T
T
L
--
D
M
-
K
-------------------
G
V
L
N
---
E
L
E
E
K
R
P
G
T
K
F
N
F
-----------------
V
R
G
Y
L
K
K
K
K
L
F
E
-
P
K
E
---------------
C
K
I
--
C
R
M
P
S
S
G
D
I
C
A
F
C
K
F
W
G
LK
K
E
I
N
FKVSSTDEEPFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
Fugue
44.00
17%
-34
- C4 -
4PKF
4
?
A:
[8-864]
K
V
L
E
Y
KG
K
K
L
N
FTPEDPAEETIPADELHEHLQKPST
A
R
T
K
R
L
K
E
R
CRWKHASAGEFIEKS
V
T
A
G
I
E
R
M
R
Y
L
T
E
A
-----
H
---
K
A
--
S
E
---------
G
K
P
-------------
E
A
I
-
R
R
A
L
--
G
L
A
N
V
L
N
K
S
T
-
L
V
-
L
Q
------
E
-
D
---
E
F
I
V
--------
G
Y
--
H
A
E
D
P
--------------
N
M
F
P
L
Y
--
P
----
E
L
---
S
H
---
M
A
V
Q
D
Y
L
R
S
D
Y
S
P
Q
P
A
D
E
A
A
-------
A
I
N
E
--------------
Y
W
K
-
P
H
S
L
Q
---
S
-
K
C
Q
--
P
Y
F
D
--
P
A
D
L
G
-
R
--
M
Y
Q
V
S
----
S
M
E
A
P
S
-
F
A
S
G
Y
N
S
I
V
P
------------------------------------
P
Y
E
T
V
L
E
D
G
L
L
---
A
--
R
I
K
L
-
A
-
E
K
H
I
-
A
E
A
Q
A
D
M
S
TFPW
N
G
T
K
------
G
L
D
N
I
----
A
K
I
D
N
----
W
K
A
M
----------
V
I
A
C
--
K
A
V
I
-------------------
S
W
A
R
---
R
Q
G
R
L
C
K
I
V
A
E
N
F
-----------------
E
T
D
P
K
R
Q
A
E
L
L
E
I
A
D
I
---------------
C
Q
R
I
P
A
E
P
C
K
G
L
K
D
A
M
Q
A
K
F
F
T
F
L
I
C
H
AIE
R
Y
A
S
G
YAQK
E
D
T
L
L
W
P
Y
Y
K
A
S
VVDKKFQPMS
H
M
D
A
V
E
L
V
E
M
E
R
L
K
I
S
E
HGAGKS
R
A
Y
R
E
I
F
PGSN
D
L
F
I
L
T
V
G
GTNAKGEDACN
D
M
T
D
A
I
L
E
A
A
K
R
IRTAEP
S
I
V
F
RYSKKNR
E
K
T
L
R
W
V
F
E
C
I
R
D
GLGYP
S
I
K
H
D
E
I
G
T
E
Q
M
K
E
Y
A
K
F
SLNGNGAT
D
E
E
A
H
NWVNVLC
M
S
P
G
I
H
G
RRKTQKTRSE
G
G
G
S
I
F
P
A
K
L
L
E
I
S
L
N
D
GYDWSYADMQLGPKTGDLSSLKS
F
E
D
V
W
E
A
F
R
K
Q
Y
Q
Y
A
I
N
L
C
I
S
T
K
D
V
S
R
Y
F
E
Q
R
FLQM
P
F
V
S
A
I
D
D
G
C
M
E
L
GMDACALSE
Q
P
N
G
W
H
N
P
I
T
T
I
V
A
A
N
S
L
V
A
I
K
K
LVFEEKKYT
L
E
Q
L
S
Q
A
L
K
A
N
WEGF
E
E
M
R
V
D
F
K
R
APKWGNDD
D
Y
A
D
G
I
I
T
R
F
Y
E
EI
I
G
G
E
M
R
K
ITNYSG
G
P
V
M
P
TGQAVG
L
Y
M
E
V
G
S
R
TGPTPDGRFGGEAADDGGISPYMGTDKKG
P
T
A
V
L
R
S
V
S
K
VQKNQK
G
N
L
L
N
Q
R
L
S
V
P
I
M
R
SKH
G
F
E
I
W
N
S
Y
I
K
T
W
H
D
L
NID
H
V
Q
F
N
VVS
T
D
E
M
R
A
A
Q
R
EPEKHHD
L
I
V
R
V
S
GYSARFVDIP
T
Y
G
Q
N
T
I
I
A
RQE
Q
D
F
S
A
S
D
L
E
F
L
NVEI